AMIC - ECOLI - GREMLIN Contacts

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AMIC - N-acetylmuramoyl-L-alanine amidase AmiC

UniProt:	P63883	Sequences: MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPASSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSARVGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLEDYNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQIARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSGSSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLKFGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQQEVAESILAGIKAYFADGATLARRG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13086
Length:	417 (368)
Sequences:	1519 (1084)
Seq/√Len:	56.5

ECOLI - AMIC AMIB AMIA
BACSU - YRVJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
339_V	370_I	5.380	1.00
223_R	227_E	4.228	1.00
210_R	213_D	4.148	1.00
227_E	234_V	3.999	1.00
218_I	374_T	3.554	1.00
262_V	403_I	3.445	1.00
226_I	232_M	3.437	1.00
194_P	219_A	3.418	1.00
221_R	393_Q	3.376	1.00
225_L	397_E	3.038	1.00
229_E	404_K	2.975	1.00
209_T	383_E	2.964	1.00
226_I	234_V	2.910	1.00
194_P	237_T	2.648	1.00
372_V	399_I	2.633	1.00
221_R	392_Q	2.608	1.00
74_D	112_R	2.515	1.00
209_T	387_K	2.504	1.00
102_R	114_V	2.496	1.00
223_R	236_M	2.404	1.00
71_V	117_L	2.392	1.00
40_R	53_E	2.305	1.00
219_A	264_I	2.296	1.00
189_V	233_K	2.269	1.00
281_A	336_G	2.187	1.00
217_Q	392_Q	2.173	1.00
102_R	116_E	2.152	1.00
232_M	404_K	2.148	1.00
107_D	110_T	2.118	1.00
205_G	383_E	2.102	1.00
49_R	141_D	2.082	1.00
260_L	403_I	2.076	1.00
65_L	70_R	2.056	1.00
358_G	363_K	2.051	1.00
63_F	72_V	2.046	1.00
204_V	210_R	2.044	1.00
268_A	378_S	2.029	1.00
191_M	237_T	1.998	1.00
279_V	340_L	1.989	1.00
219_A	236_M	1.954	1.00
217_Q	221_R	1.946	1.00
226_I	400_L	1.935	1.00
296_A	300_N	1.930	1.00
277_S	347_N	1.878	1.00
248_V	251_A	1.878	1.00
70_R	114_V	1.866	1.00
51_T	137_R	1.866	1.00
66_S	69_E	1.846	0.99
254_Q	366_D	1.839	0.99
218_I	395_V	1.835	0.99
137_R	141_D	1.784	0.99
65_L	114_V	1.782	0.99
275_S	385_K	1.768	0.99
288_T	296_A	1.765	0.99
225_L	393_Q	1.760	0.99
128_L	137_R	1.754	0.99
49_R	137_R	1.746	0.99
65_L	68_P	1.743	0.99
223_R	234_V	1.742	0.99
315_Y	319_T	1.738	0.99
74_D	102_R	1.715	0.99
130_P	136_E	1.707	0.99
65_L	74_D	1.694	0.99
267_D	278_S	1.684	0.99
192_L	219_A	1.682	0.99
229_E	400_L	1.673	0.99
104_G	114_V	1.664	0.99
50_V	115_F	1.660	0.99
40_R	49_R	1.640	0.99
192_L	234_V	1.632	0.99
221_R	389_A	1.616	0.99
102_R	112_R	1.607	0.99
225_L	228_K	1.596	0.98
335_F	370_I	1.586	0.98
191_M	252_K	1.576	0.98
126_F	141_D	1.566	0.98
70_R	74_D	1.561	0.98
245_P	248_V	1.561	0.98
70_R	112_R	1.552	0.98
72_V	114_V	1.535	0.98
40_R	137_R	1.523	0.98
191_M	234_V	1.520	0.98
281_A	333_L	1.518	0.98
52_V	113_M	1.513	0.98
40_R	141_D	1.495	0.98
275_S	381_E	1.494	0.98
53_E	137_R	1.483	0.97
51_T	139_V	1.481	0.97
73_V	140_M	1.459	0.97
106_F	110_T	1.456	0.97
269_F	274_P	1.452	0.97
224_S	228_K	1.448	0.97
189_V	235_Y	1.445	0.97
68_P	114_V	1.425	0.97
74_D	114_V	1.424	0.97
221_R	224_S	1.411	0.97
49_R	139_V	1.408	0.97
264_I	374_T	1.408	0.97
333_L	336_G	1.401	0.96
289_S	355_E	1.398	0.96
190_I	260_L	1.397	0.96
391_F	395_V	1.395	0.96
40_R	139_V	1.393	0.96
291_A	325_Q	1.381	0.96
382_E	391_F	1.380	0.96
235_Y	252_K	1.366	0.96
40_R	51_T	1.365	0.96
53_E	139_V	1.364	0.96
70_R	102_R	1.361	0.96
65_L	112_R	1.357	0.96
280_F	292_A	1.323	0.95
342_K	405_A	1.283	0.94
340_L	349_L	1.283	0.94
186_R	259_D	1.279	0.94
246_L	360_A	1.279	0.94
54_S	58_L	1.279	0.94
207_Y	383_E	1.259	0.94
250_V	364_A	1.256	0.94
30_L	33_V	1.251	0.93
74_D	104_G	1.242	0.93
53_E	141_D	1.241	0.93
296_A	299_Q	1.238	0.93
292_A	296_A	1.236	0.93
44_A	199_E	1.233	0.93
333_L	356_Q	1.226	0.93
383_E	387_K	1.225	0.93
42_W	199_E	1.215	0.92
271_S	274_P	1.215	0.92
205_G	214_V	1.208	0.92
130_P	141_D	1.203	0.92
42_W	45_S	1.200	0.92
63_F	114_V	1.189	0.92
192_L	223_R	1.188	0.91
68_P	74_D	1.184	0.91
126_F	139_V	1.181	0.91
278_S	391_F	1.180	0.91
187_P	233_K	1.177	0.91
300_N	359_F	1.176	0.91
344_G	349_L	1.172	0.91
260_L	335_F	1.171	0.91
187_P	230_G	1.166	0.91
49_R	126_F	1.165	0.91
40_R	130_P	1.159	0.90
26_S	33_V	1.155	0.90
65_L	102_R	1.151	0.90
68_P	102_R	1.150	0.90
40_R	128_L	1.148	0.90
286_G	289_S	1.143	0.90
329_I	356_Q	1.138	0.90
188_I	407_F	1.129	0.89
75_I	78_V	1.129	0.89
96_P	118_K	1.125	0.89
363_K	367_I	1.120	0.89
343_L	395_V	1.114	0.89
191_M	258_A	1.100	0.88
254_Q	364_A	1.096	0.88
73_V	115_F	1.095	0.88
225_L	400_L	1.092	0.88
28_V	32_A	1.089	0.87
65_L	104_G	1.088	0.87
292_A	300_N	1.087	0.87
220_R	239_N	1.085	0.87
342_K	345_K	1.073	0.87
381_E	385_K	1.073	0.87
215_V	236_M	1.072	0.87
49_R	128_L	1.071	0.87
104_G	112_R	1.067	0.86
385_K	391_F	1.066	0.86
117_L	121_V	1.054	0.86
192_L	222_L	1.049	0.85
267_D	277_S	1.046	0.85
52_V	75_I	1.039	0.85
194_P	215_V	1.038	0.85
191_M	194_P	1.038	0.85
269_F	272_R	1.028	0.84
70_R	104_G	1.023	0.84
70_R	116_E	1.020	0.84
128_L	141_D	1.020	0.84
243_F	246_L	1.019	0.84
124_Q	264_I	1.017	0.84
281_A	288_T	1.015	0.83
225_L	229_E	1.013	0.83
51_T	141_D	1.012	0.83
281_A	356_Q	1.009	0.83
347_N	375_A	1.005	0.83
296_A	359_F	1.004	0.83
247_Q	360_A	1.004	0.83
281_A	354_V	1.002	0.83
379_N	383_E	0.993	0.82
115_F	142_L	0.989	0.82
274_P	350_H	0.988	0.82
63_F	74_D	0.983	0.81
71_V	121_V	0.981	0.81
319_T	323_M	0.977	0.81
29_S	33_V	0.976	0.81
385_K	388_T	0.972	0.81
40_R	126_F	0.966	0.80
63_F	70_R	0.964	0.80
42_W	141_D	0.960	0.80
62_Q	125_L	0.959	0.80
235_Y	256_Q	0.958	0.80
126_F	137_R	0.958	0.80
206_K	383_E	0.957	0.80
261_F	359_F	0.956	0.80
254_Q	365_P	0.954	0.79
288_T	300_N	0.953	0.79
63_F	112_R	0.952	0.79
27_Q	32_A	0.949	0.79
215_V	266_A	0.949	0.79
27_Q	30_L	0.949	0.79
247_Q	290_T	0.947	0.79
74_D	116_E	0.946	0.79
44_A	47_Y	0.938	0.78
170_V	173_A	0.934	0.78
323_M	366_D	0.932	0.78
350_H	377_I	0.930	0.78
203_A	377_I	0.927	0.77
246_L	359_F	0.925	0.77
80_L	98_I	0.918	0.77
325_Q	328_T	0.917	0.77
53_E	126_F	0.912	0.76
248_V	252_K	0.907	0.76
250_V	360_A	0.903	0.76
48_T	141_D	0.899	0.75
190_I	232_M	0.898	0.75
338_A	402_G	0.887	0.74
42_W	134_F	0.882	0.74
128_L	139_V	0.879	0.74
31_A	55_N	0.877	0.73
205_G	382_E	0.873	0.73
288_T	356_Q	0.868	0.73
232_M	375_A	0.867	0.73
222_L	399_I	0.866	0.73
130_P	135_K	0.864	0.72
224_S	393_Q	0.863	0.72
40_R	48_T	0.862	0.72
331_D	406_Y	0.859	0.72
42_W	126_F	0.852	0.71
91_I	101_A	0.851	0.71
123_P	143_Y	0.850	0.71
342_K	401_A	0.848	0.71
77_D	109_Q	0.847	0.71
220_R	240_E	0.841	0.70
284_T	326_S	0.840	0.70
104_G	116_E	0.836	0.70
213_D	387_K	0.835	0.70
71_V	398_S	0.833	0.70
393_Q	397_E	0.833	0.70
100_S	116_E	0.832	0.69
23_L	26_S	0.830	0.69
350_H	355_E	0.829	0.69
277_S	375_A	0.829	0.69
28_V	31_A	0.827	0.69
97_F	121_V	0.823	0.69
292_A	299_Q	0.822	0.69
134_F	199_E	0.821	0.68
223_R	239_N	0.818	0.68
38_A	53_E	0.817	0.68
112_R	116_E	0.814	0.68
207_Y	380_V	0.814	0.68
250_V	367_I	0.813	0.68
232_M	407_F	0.812	0.68
175_S	183_G	0.810	0.67
192_L	226_I	0.808	0.67
281_A	329_I	0.807	0.67
19_A	26_S	0.802	0.67
269_F	350_H	0.801	0.67
26_S	30_L	0.796	0.66
314_R	318_H	0.794	0.66
148_Q	177_P	0.789	0.65
220_R	223_R	0.789	0.65
253_A	367_I	0.788	0.65
294_Y	367_I	0.783	0.65
25_V	29_S	0.778	0.64
179_P	182_A	0.778	0.64
296_A	303_D	0.776	0.64
375_A	391_F	0.761	0.63
218_I	392_Q	0.760	0.62
242_I	245_P	0.759	0.62
330_A	375_A	0.757	0.62
358_G	365_P	0.757	0.62
254_Q	278_S	0.755	0.62
39_V	50_V	0.755	0.62
355_E	375_A	0.753	0.62
339_V	399_I	0.752	0.62
354_V	359_F	0.751	0.61
261_F	300_N	0.751	0.61
267_D	350_H	0.749	0.61
213_D	217_Q	0.746	0.61
146_N	149_D	0.746	0.61
300_N	303_D	0.740	0.60
390_T	394_E	0.740	0.60
327_L	331_D	0.737	0.60
336_G	356_Q	0.737	0.60
201_S	210_R	0.736	0.60
218_I	391_F	0.733	0.60
254_Q	367_I	0.733	0.60
325_Q	375_A	0.732	0.60
47_Y	141_D	0.729	0.59
347_N	391_F	0.729	0.59
222_L	400_L	0.729	0.59
53_E	130_P	0.728	0.59
303_D	307_G	0.726	0.59
290_T	294_Y	0.726	0.59
204_V	383_E	0.725	0.59
113_M	237_T	0.725	0.59
374_T	399_I	0.724	0.59
103_V	113_M	0.724	0.59
27_Q	31_A	0.723	0.59
72_V	112_R	0.723	0.59
334_K	410_G	0.718	0.58
251_A	255_K	0.718	0.58
62_Q	71_V	0.717	0.58
189_V	389_A	0.717	0.58
73_V	93_A	0.711	0.57
50_V	73_V	0.711	0.57
232_M	402_G	0.710	0.57
47_Y	143_Y	0.709	0.57
262_V	372_V	0.704	0.57
23_L	341_N	0.703	0.56
130_P	134_F	0.703	0.56
248_V	255_K	0.700	0.56
29_S	32_A	0.700	0.56
355_E	377_I	0.699	0.56
335_F	407_F	0.698	0.56
277_S	343_L	0.697	0.56
290_T	293_K	0.696	0.56
53_E	135_K	0.694	0.55
385_K	394_E	0.694	0.55
218_I	396_A	0.694	0.55
325_Q	365_P	0.690	0.55
69_E	120_N	0.690	0.55
268_A	272_R	0.689	0.55
344_G	348_K	0.687	0.55
65_L	72_V	0.686	0.55
218_I	264_I	0.686	0.55
24_S	190_I	0.685	0.54
296_A	378_S	0.683	0.54
311_S	314_R	0.682	0.54
250_V	365_P	0.679	0.54
130_P	137_R	0.677	0.54
22_L	26_S	0.675	0.53
289_S	296_A	0.674	0.53
23_L	33_V	0.673	0.53
332_S	354_V	0.673	0.53
252_K	256_Q	0.673	0.53
43_P	47_Y	0.672	0.53
63_F	102_R	0.672	0.53
175_S	190_I	0.670	0.53
68_P	112_R	0.669	0.53
254_Q	267_D	0.666	0.52
342_K	402_G	0.665	0.52
42_W	137_R	0.663	0.52
346_I	398_S	0.662	0.52
49_R	53_E	0.658	0.52
28_V	33_V	0.658	0.52
190_I	222_L	0.657	0.51
218_I	222_L	0.654	0.51
224_S	227_E	0.652	0.51
25_V	28_V	0.651	0.51
20_M	28_V	0.650	0.51
295_L	359_F	0.648	0.50
127_A	262_V	0.648	0.50
179_P	185_D	0.647	0.50
328_T	365_P	0.646	0.50
176_G	180_G	0.646	0.50
381_E	388_T	0.645	0.50
19_A	29_S	0.644	0.50
194_P	223_R	0.642	0.50
324_V	328_T	0.641	0.50
288_T	292_A	0.640	0.50
340_L	344_G	0.639	0.49
331_D	402_G	0.639	0.49
43_P	144_P	0.638	0.49
296_A	354_V	0.637	0.49
61_K	65_L	0.636	0.49
227_E	399_I	0.631	0.49
262_V	370_I	0.631	0.49
75_I	138_L	0.630	0.49
251_A	310_K	0.630	0.49
336_G	349_L	0.629	0.48
27_Q	33_V	0.629	0.48
36_V	52_V	0.624	0.48
221_R	225_L	0.624	0.48
239_N	375_A	0.624	0.48
267_D	364_A	0.623	0.48
206_K	272_R	0.623	0.48
399_I	403_I	0.619	0.47
42_W	49_R	0.617	0.47
300_N	332_S	0.614	0.47
205_G	377_I	0.611	0.46
293_K	297_Q	0.611	0.46
21_W	37_V	0.611	0.46
309_S	324_V	0.609	0.46
205_G	380_V	0.609	0.46
61_K	76_E	0.608	0.46
172_P	183_G	0.608	0.46
340_L	351_K	0.608	0.46
250_V	290_T	0.607	0.46
375_A	400_L	0.606	0.46
317_D	324_V	0.606	0.46
175_S	182_A	0.606	0.46
236_M	264_I	0.605	0.46
267_D	366_D	0.603	0.46
30_L	34_S	0.601	0.45
36_V	78_V	0.601	0.45
272_R	391_F	0.599	0.45
105_Q	110_T	0.599	0.45
300_N	354_V	0.596	0.45
277_S	391_F	0.596	0.45
63_F	68_P	0.594	0.45
184_R	189_V	0.593	0.45
24_S	27_Q	0.591	0.44
67_N	147_A	0.589	0.44
123_P	126_F	0.589	0.44
250_V	358_G	0.589	0.44
62_Q	122_K	0.587	0.44
321_F	325_Q	0.585	0.44
42_W	128_L	0.584	0.44
209_T	214_V	0.582	0.43
42_W	47_Y	0.581	0.43
131_V	134_F	0.581	0.43
140_M	401_A	0.581	0.43
67_N	251_A	0.579	0.43
72_V	102_R	0.578	0.43
300_N	305_I	0.576	0.43
140_M	409_D	0.576	0.43
280_F	355_E	0.576	0.43
71_V	75_I	0.574	0.42
329_I	406_Y	0.573	0.42
31_A	34_S	0.573	0.42
250_V	261_F	0.570	0.42
342_K	398_S	0.570	0.42
279_V	351_K	0.570	0.42
335_F	398_S	0.569	0.42
60_Y	317_D	0.569	0.42
173_A	182_A	0.568	0.42
278_S	364_A	0.568	0.42
229_E	232_M	0.568	0.42
277_S	349_L	0.568	0.42
122_K	145_A	0.567	0.42
236_M	330_A	0.566	0.42
128_L	136_E	0.564	0.41
377_I	383_E	0.563	0.41
319_T	364_A	0.563	0.41
232_M	400_L	0.563	0.41
377_I	380_V	0.561	0.41
335_F	339_V	0.561	0.41
188_I	406_Y	0.559	0.41
22_L	29_S	0.556	0.41
400_L	404_K	0.556	0.41
324_V	327_L	0.556	0.41
374_T	386_L	0.556	0.41
397_E	401_A	0.555	0.40
280_F	300_N	0.554	0.40
174_Q	177_P	0.553	0.40
323_M	327_L	0.553	0.40
243_F	303_D	0.551	0.40
358_G	367_I	0.550	0.40
389_A	392_Q	0.550	0.40
301_A	305_I	0.550	0.40
237_T	244_I	0.549	0.40
312_G	326_S	0.549	0.40
32_A	55_N	0.545	0.39
247_Q	311_S	0.545	0.39
57_Q	75_I	0.544	0.39
99_K	118_K	0.544	0.39
170_V	179_P	0.544	0.39
282_L	321_F	0.543	0.39
269_F	294_Y	0.542	0.39
25_V	30_L	0.542	0.39
355_E	376_F	0.542	0.39
77_D	341_N	0.542	0.39
219_A	222_L	0.541	0.39
176_G	179_P	0.541	0.39
106_F	114_V	0.540	0.39
77_D	108_P	0.540	0.39
68_P	104_G	0.539	0.39
179_P	190_I	0.539	0.39
239_N	341_N	0.538	0.39
289_S	293_K	0.538	0.39
329_I	354_V	0.537	0.39
169_Q	175_S	0.535	0.38
22_L	27_Q	0.534	0.38
283_S	321_F	0.533	0.38
73_V	221_R	0.532	0.38
304_L	321_F	0.532	0.38
40_R	143_Y	0.532	0.38
268_A	377_I	0.532	0.38
113_M	136_E	0.531	0.38
64_A	69_E	0.530	0.38
230_G	234_V	0.530	0.38
174_Q	181_K	0.530	0.38
103_V	111_V	0.530	0.38
80_L	111_V	0.529	0.38
126_F	130_P	0.529	0.38
175_S	178_Q	0.529	0.38
280_F	359_F	0.529	0.38
205_G	209_T	0.528	0.38
20_M	26_S	0.528	0.38
68_P	369_S	0.528	0.38
178_Q	390_T	0.527	0.38
280_F	356_Q	0.527	0.38
45_S	199_E	0.527	0.38
121_V	142_L	0.525	0.37
292_A	357_A	0.524	0.37
210_R	393_Q	0.524	0.37
320_M	336_G	0.523	0.37
143_Y	252_K	0.523	0.37
60_Y	335_F	0.523	0.37
317_D	366_D	0.520	0.37
49_R	130_P	0.519	0.37
261_F	354_V	0.519	0.37
281_A	355_E	0.519	0.37
212_K	300_N	0.519	0.37
172_P	405_A	0.519	0.37
41_V	91_I	0.518	0.37
140_M	251_A	0.518	0.37
299_Q	359_F	0.517	0.37
100_S	104_G	0.517	0.37
180_G	183_G	0.516	0.36
46_S	51_T	0.515	0.36
398_S	405_A	0.515	0.36
26_S	35_Q	0.514	0.36
220_R	236_M	0.514	0.36
333_L	358_G	0.514	0.36
56_R	394_E	0.513	0.36
261_F	361_V	0.513	0.36
98_I	117_L	0.513	0.36
326_S	354_V	0.512	0.36
254_Q	328_T	0.511	0.36
68_P	116_E	0.511	0.36
187_P	247_Q	0.509	0.36
244_I	318_H	0.509	0.36
191_M	235_Y	0.508	0.36
206_K	380_V	0.508	0.36
69_E	121_V	0.508	0.36
289_S	359_F	0.507	0.36
268_A	350_H	0.507	0.36
278_S	350_H	0.507	0.36
321_F	366_D	0.506	0.35
174_Q	179_P	0.505	0.35
283_S	288_T	0.505	0.35
193_D	249_R	0.505	0.35
286_G	327_L	0.505	0.35
214_V	326_S	0.504	0.35
228_K	389_A	0.502	0.35
110_T	150_M	0.502	0.35
305_I	309_S	0.502	0.35
212_K	241_D	0.501	0.35
94_D	215_V	0.500	0.35
378_S	383_E	0.500	0.35

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4binA	1	0.8345	100	0.227	Contact Map
3ne8A	2	0.5396	100	0.438	Contact Map
4rn7A	1	0.4388	100	0.519	Contact Map
1jwqA	1	0.4245	100	0.522	Contact Map
4lq6A	1	0.4412	100	0.527	Contact Map
1xovA	1	0.4365	100	0.533	Contact Map
3czxA	2	0.4197	100	0.55	Contact Map
3qayA	1	0.4101	100	0.566	Contact Map
4av2A	3	0.4604	99.1	0.894	Contact Map
4aqzA	1	0.3213	97.7	0.931	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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