GREMLIN Database
EUTS - Ethanolamine utilization protein EutS
UniProt: P63746 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14192
Length: 111 (108)
Sequences: 274 (164)
Seq/√Len: 15.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
46_L51_T4.0821.00
16_V97_L4.0791.00
21_L90_L4.0491.00
82_S85_A3.2410.99
87_E110_K3.1080.99
10_F47_T2.9430.98
30_A33_I2.6750.96
41_I80_Y2.6300.96
6_I10_F2.4910.94
92_Q95_S1.8770.80
96_G100_L1.8570.80
51_T103_Y1.7870.77
60_L78_V1.7040.73
35_V68_G1.6750.72
67_I88_E1.5860.68
33_I76_A1.5450.66
92_Q108_M1.5210.64
18_L47_T1.4850.62
91_S107_E1.4690.61
32_K35_V1.4270.59
28_E66_H1.4260.59
29_L70_L1.4020.58
51_T58_L1.3770.56
4_E101_L1.3760.56
87_E91_S1.3590.55
56_G106_C1.3550.55
77_L93_T1.3530.55
14_K97_L1.3050.52
70_L103_Y1.2990.52
16_V49_G1.2630.50
21_L63_A1.2590.50
97_L105_L1.2490.49
8_Q32_K1.2180.47
49_G76_A1.1930.46
12_P15_Q1.1850.45
58_L96_G1.1770.45
64_D85_A1.1740.45
65_V79_I1.1670.44
74_S94_V1.1470.43
95_S108_M1.1160.41
39_G106_C1.1110.41
18_L101_L1.1010.41
15_Q45_T1.0960.40
60_L108_M1.0940.40
95_S99_R1.0830.40
7_I23_A1.0770.39
67_I87_E1.0520.38
69_F73_F1.0380.37
19_A103_Y1.0310.37
26_G104_T1.0270.37
9_E25_P0.9940.35
10_F49_G0.9920.35
69_F90_L0.9560.33
44_M77_L0.9480.32
49_G88_E0.9470.32
76_A106_C0.9430.32
37_D107_E0.9370.32
21_L99_R0.9350.32
17_T54_I0.9280.31
44_M93_T0.9260.31
24_H49_G0.9250.31
30_A93_T0.9210.31
41_I89_A0.9140.31
35_V80_Y0.9060.30
33_I49_G0.9010.30
36_P58_L0.8970.30
83_V87_E0.8940.30
92_Q107_E0.8880.29
14_K103_Y0.8880.29
9_E54_I0.8760.29
36_P62_A0.8690.29
62_A82_S0.8670.29
46_L74_S0.8670.29
41_I70_L0.8560.28
63_A67_I0.8550.28
51_T62_A0.8440.27
94_V105_L0.8400.27
18_L77_L0.8370.27
31_K35_V0.8180.26
21_L27_E0.8120.26
12_P45_T0.8060.26
7_I15_Q0.7870.25
51_T105_L0.7790.25
93_T101_L0.7690.24
37_D44_M0.7690.24
88_E110_K0.7630.24
37_D76_A0.7620.24
30_A49_G0.7550.24
36_P41_I0.7510.23
41_I108_M0.7440.23
9_E32_K0.7410.23
66_H96_G0.7380.23
41_I68_G0.7370.23
92_Q96_G0.7370.23
33_I80_Y0.7210.22
6_I56_G0.7200.22
63_A70_L0.7170.22
45_T79_I0.7120.22
100_L107_E0.7100.22
26_G30_A0.7060.22
56_G82_S0.7020.21
74_S88_E0.6950.21
64_D99_R0.6930.21
16_V96_G0.6830.21
84_G105_L0.6800.21
72_R75_G0.6760.20
82_S90_L0.6750.20
95_S98_G0.6670.20
65_V91_S0.6660.20
18_L60_L0.6640.20
55_A90_L0.6630.20
44_M63_A0.6580.20
26_G84_G0.6540.20
66_H108_M0.6530.20
91_S95_S0.6520.20
28_E46_L0.6520.20
17_T25_P0.6430.19
80_Y106_C0.6380.19
86_V101_L0.6380.19
16_V51_T0.6350.19
77_L90_L0.6230.19
9_E109_T0.6080.18
26_G32_K0.6060.18
67_I78_V0.6000.18
35_V74_S0.5990.18
33_I36_P0.5940.18
23_A70_L0.5940.18
45_T53_M0.5940.18
69_F72_R0.5900.17
68_G89_A0.5870.17
18_L76_A0.5840.17
32_K88_E0.5820.17
25_P54_I0.5780.17
39_G105_L0.5760.17
52_A103_Y0.5750.17
44_M82_S0.5730.17
8_Q54_I0.5700.17
31_K38_A0.5680.17
62_A66_H0.5670.17
67_I85_A0.5650.17
10_F53_M0.5650.17
4_E93_T0.5640.17
19_A94_V0.5590.16
35_V96_G0.5590.16
95_S107_E0.5570.16
27_E31_K0.5560.16
99_R110_K0.5510.16
12_P20_H0.5440.16
91_S110_K0.5410.16
98_G107_E0.5340.16
64_D80_Y0.5300.16
35_V46_L0.5260.15
38_A70_L0.5250.15
16_V28_E0.5220.15
46_L70_L0.5210.15
8_Q25_P0.5180.15
25_P109_T0.5150.15
64_D79_I0.5150.15
56_G77_L0.5130.15
85_A100_L0.5120.15
47_T105_L0.5040.15
26_G67_I0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3i96A 5 1 100 0.428 Contact Map
4axiA 5 1 100 0.435 Contact Map
3cgiA 6 1 100 0.454 Contact Map
4fayA 3 0.9459 99.9 0.526 Contact Map
3io0A 3 0.964 99.9 0.55 Contact Map
3gfhA 3 0.9459 99.8 0.625 Contact Map
4tlhA 3 0.9279 99.8 0.627 Contact Map
3u27C 4 0.955 99.8 0.638 Contact Map
4oloA 3 0.7658 99.7 0.69 Contact Map
3nwgA 5 0.991 99.6 0.692 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0058 seconds.