GREMLIN Database
YHES - Uncharacterized ABC transporter ATP-binding protein YheS
UniProt: P63389 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12903
Length: 637 (518)
Sequences: 4985 (3545)
Seq/√Len: 155.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
577_Q605_Q4.7911.00
210_D232_S4.1821.00
317_K330_S4.0321.00
563_E619_A3.9971.00
260_Q264_D3.7261.00
315_M318_V3.4551.00
391_D429_R3.3791.00
570_E612_G3.2091.00
491_R513_E2.9981.00
263_I280_I2.9971.00
608_S612_G2.8831.00
598_E601_A2.8761.00
215_K226_E2.8471.00
316_E368_E2.8151.00
610_K614_E2.7971.00
389_R392_E2.7441.00
320_A365_V2.6741.00
392_E400_R2.6261.00
318_V364_P2.5551.00
578_L609_A2.5041.00
225_F241_R2.4401.00
326_I329_D2.4261.00
570_E616_C2.4221.00
320_A357_L2.4141.00
233_S237_Q2.3551.00
267_R280_I2.2881.00
145_R149_D2.2691.00
577_Q580_Q2.2351.00
574_L616_C2.2131.00
355_I483_V2.2091.00
582_E606_Q2.1981.00
566_R570_E2.1931.00
321_G365_V2.1861.00
567_L616_C2.1521.00
561_R565_A2.1511.00
213_V216_I2.1431.00
581_A602_C2.1251.00
193_K211_P2.1221.00
584_K598_E2.1181.00
339_S496_D2.1151.00
604_Q608_S2.0921.00
601_A605_Q2.0911.00
121_D124_S2.0661.00
584_K587_D2.0641.00
580_Q584_K2.0561.00
335_L341_I2.0531.00
582_E610_K2.0441.00
249_Y253_Q2.0321.00
571_M613_L2.0021.00
116_K120_I2.0011.00
128_R167_R1.9811.00
233_S236_V1.9561.00
342_G490_L1.9511.00
578_L606_Q1.9351.00
236_V240_T1.9291.00
227_Y241_R1.9291.00
572_E575_N1.8951.00
617_E621_L1.8781.00
605_Q608_S1.8721.00
142_Q145_R1.8591.00
573_K577_Q1.8571.00
269_K272_K1.8541.00
280_I284_E1.8531.00
357_L364_P1.8411.00
117_L122_A1.8171.00
319_S366_S1.8101.00
574_L609_A1.8041.00
255_R258_H1.8031.00
237_Q240_T1.8031.00
581_A609_A1.7931.00
562_K565_A1.7851.00
278_S281_K1.7621.00
277_Q280_I1.7581.00
317_K332_K1.7471.00
315_M333_L1.7341.00
428_T439_L1.7321.00
600_T604_Q1.7101.00
341_I498_Y1.6991.00
189_E211_P1.6971.00
254_E257_A1.6931.00
597_A601_A1.6571.00
577_Q609_A1.6551.00
146_P149_D1.6541.00
239_A243_A1.6401.00
614_E618_M1.6361.00
277_Q281_K1.6331.00
357_L369_I1.6291.00
240_T244_Q1.6211.00
266_F269_K1.6121.00
240_T243_A1.6031.00
564_I623_A1.5961.00
244_Q248_M1.5921.00
572_E576_A1.5861.00
576_A580_Q1.5791.00
606_Q610_K1.5781.00
612_G616_C1.5591.00
569_K572_E1.5581.00
578_L610_K1.5531.00
172_L202_I1.5491.00
618_M621_L1.5451.00
315_M358_L1.5351.00
570_E573_K1.5271.00
323_G326_I1.5171.00
496_D507_P1.5101.00
359_A453_L1.5041.00
263_I283_L1.5001.00
109_A112_T1.4981.00
256_V288_L1.4981.00
356_K361_E1.4961.00
321_G326_I1.4911.00
551_A554_R1.4861.00
511_D514_D1.4841.00
218_H234_F1.4831.00
147_V158_L1.4811.00
562_K566_R1.4731.00
609_A612_G1.4681.00
259_L282_M1.4641.00
605_Q609_A1.4591.00
394_P439_L1.4351.00
328_L331_I1.4291.00
575_N613_L1.4211.00
267_R270_A1.4201.00
261_S264_D1.4171.00
557_T561_R1.4161.00
558_Q562_K1.4091.00
607_A611_S1.4071.00
237_Q241_R1.3991.00
574_L578_L1.3941.00
357_L365_V1.3931.00
578_L582_E1.3921.00
571_M575_N1.3881.00
260_Q288_L1.3731.00
615_E619_A1.3711.00
342_G494_T1.3621.00
217_I224_M1.3521.00
550_E554_R1.3521.00
311_P370_G1.3481.00
548_R551_A1.3451.00
619_A623_A1.3411.00
588_S591_Y1.3381.00
612_G615_E1.3321.00
230_N233_S1.3261.00
618_M622_E1.3171.00
449_P476_F1.3151.00
393_S396_Q1.3111.00
329_D504_K1.2991.00
587_D590_L1.2961.00
112_T116_K1.2941.00
314_K370_G1.2911.00
482_V494_T1.2901.00
584_K602_C1.2891.00
281_K284_E1.2851.00
621_L625_E1.2821.00
405_E409_K1.2801.00
611_S614_E1.2771.00
392_E397_H1.2761.00
619_A622_E1.2721.00
333_L498_Y1.2641.00
397_H443_L1.2631.00
579_A582_E1.2621.00
578_L613_L1.2591.00
598_E602_C1.2581.00
582_E586_G1.2581.00
397_H428_T1.2551.00
577_Q584_K1.2551.00
615_E618_M1.2551.00
473_L480_L1.2501.00
276_A280_I1.2451.00
378_G449_P1.2441.00
557_T560_L1.2441.00
218_H238_R1.2421.00
567_L623_A1.2401.00
266_F272_K1.2391.00
275_Q283_L1.2331.00
396_Q399_A1.2301.00
426_E430_R1.2261.00
579_A583_E1.2241.00
229_G237_Q1.2171.00
574_L613_L1.2151.00
585_L590_L1.2141.00
318_V369_I1.2111.00
318_V357_L1.2111.00
549_R553_L1.2051.00
246_Q250_E1.2011.00
108_H112_T1.1981.00
570_E574_L1.1971.00
556_Q560_L1.1961.00
217_I226_E1.1951.00
604_Q607_A1.1921.00
115_G118_D1.1891.00
560_L623_A1.1891.00
390_A429_R1.1881.00
115_G119_A1.1861.00
201_L213_V1.1781.00
501_H506_E1.1761.00
277_Q285_R1.1701.00
252_Q289_I1.1681.00
564_I624_Q1.1631.00
547_K550_E1.1631.00
555_A558_Q1.1621.00
320_A362_L1.1611.00
516_Q519_L1.1601.00
229_G233_S1.1551.00
155_R383_H1.1541.00
406_L409_K1.1531.00
253_Q256_V1.1441.00
170_L198_T1.1421.00
274_K280_I1.1421.00
603_L607_A1.1411.00
563_E567_L1.1411.00
451_L481_V1.1411.00
394_P428_T1.1381.00
150_F158_L1.1381.00
547_K551_A1.1371.00
601_A604_Q1.1331.00
315_M369_I1.1301.00
609_A613_L1.1301.00
276_A279_R1.1291.00
126_R130_A1.1291.00
560_L564_I1.1221.00
580_Q583_E1.1201.00
107_G110_I1.1191.00
372_A375_I1.1131.00
279_R283_L1.1131.00
249_Y252_Q1.1121.00
473_L493_T1.1060.99
276_A283_L1.1060.99
268_A272_K1.1040.99
275_Q281_K1.1010.99
341_I481_V1.0870.99
219_I224_M1.0850.99
510_G514_D1.0810.99
552_E556_Q1.0800.99
331_I498_Y1.0760.99
585_L603_L1.0750.99
414_L417_F1.0750.99
548_R552_E1.0730.99
139_S142_Q1.0690.99
172_L200_I1.0660.99
190_K193_K1.0650.99
607_A610_K1.0630.99
614_E621_L1.0600.99
567_L571_M1.0590.99
262_Y275_Q1.0570.99
589_E592_D1.0530.99
568_E572_E1.0510.99
392_E396_Q1.0500.99
275_Q278_S1.0470.99
614_E617_E1.0470.99
356_K362_L1.0460.99
376_K447_Q1.0440.99
274_K278_S1.0440.99
292_A296_N1.0440.99
559_P562_K1.0420.99
559_P563_E1.0390.99
124_S128_R1.0380.99
328_L357_L1.0370.99
352_S356_K1.0350.99
109_A113_I1.0300.99
316_E332_K1.0290.99
183_D346_R1.0270.99
371_L375_I1.0250.99
273_A277_Q1.0250.99
274_K277_Q1.0240.99
423_K426_E1.0240.99
106_D109_A1.0210.99
278_S283_L1.0200.99
111_A115_G1.0170.99
554_R558_Q1.0150.99
275_Q287_E1.0150.99
276_A287_E1.0140.99
482_V490_L1.0140.99
565_A569_K1.0130.99
602_C605_Q1.0110.99
167_R196_Q1.0100.99
518_W522_V1.0080.99
408_Q412_D1.0070.99
542_A545_D1.0010.99
286_M289_I0.9990.99
276_A285_R0.9970.99
192_L199_L0.9960.99
514_D517_Q0.9940.99
546_Q550_E0.9930.99
577_Q581_A0.9900.99
546_Q549_R0.9870.99
252_Q286_M0.9870.99
276_A281_K0.9860.99
581_A606_Q0.9820.99
608_S611_S0.9810.99
244_Q247_A0.9770.99
277_Q283_L0.9700.99
293_H296_N0.9700.99
402_A407_E0.9660.99
256_V283_L0.9650.99
524_K528_Q0.9650.99
346_R349_A0.9640.99
558_Q561_R0.9630.99
566_R569_K0.9620.99
281_K285_R0.9620.99
322_Y327_I0.9600.99
243_A247_A0.9580.99
560_L563_E0.9550.99
278_S285_R0.9540.98
453_L481_V0.9540.98
482_V493_T0.9470.98
283_L286_M0.9470.98
290_A296_N0.9450.98
319_S330_S0.9440.98
583_E587_D0.9440.98
519_L522_V0.9440.98
540_A544_K0.9430.98
618_M625_E0.9410.98
544_K547_K0.9410.98
550_E553_L0.9400.98
522_V525_Q0.9390.98
264_D267_R0.9370.98
242_L246_Q0.9330.98
207_D488_H0.9320.98
255_R286_M0.9300.98
523_Q526_E0.9290.98
190_K194_S0.9290.98
599_L603_L0.9280.98
116_K119_A0.9270.98
278_S286_M0.9250.98
391_D427_E0.9210.98
268_A271_T0.9200.98
548_R554_R0.9190.98
285_R289_I0.9190.98
611_S615_E0.9190.98
279_R286_M0.9190.98
546_Q551_A0.9170.98
569_K573_K0.9170.98
482_V489_L0.9150.98
319_S329_D0.9140.98
267_R271_T0.9090.98
515_Y519_L0.9060.98
585_L599_L0.9020.98
571_M617_E0.9020.98
320_A353_T0.9000.98
261_S265_R0.8970.98
525_Q528_Q0.8960.98
267_R272_K0.8930.98
567_L619_A0.8930.98
101_A105_N0.8920.98
552_E555_A0.8890.98
284_E288_L0.8830.98
490_L494_T0.8760.97
308_L375_I0.8740.97
313_L371_L0.8740.97
581_A605_Q0.8740.97
275_Q285_R0.8740.97
513_E517_Q0.8710.97
364_P369_I0.8680.97
528_Q532_A0.8660.97
568_E575_N0.8660.97
269_K273_A0.8570.97
575_N617_E0.8550.97
545_D548_R0.8520.97
321_G324_D0.8510.97
243_A246_Q0.8500.97
590_L602_C0.8490.97
280_I283_L0.8490.97
409_K412_D0.8480.97
412_D416_G0.8470.97
227_Y234_F0.8460.97
310_N336_V0.8430.97
553_L556_Q0.8430.97
322_Y362_L0.8420.97
603_L606_Q0.8410.97
270_A273_A0.8370.97
266_F273_A0.8360.97
504_K507_P0.8350.97
395_I399_A0.8350.97
549_R552_E0.8350.97
266_F270_A0.8330.96
514_D518_W0.8330.96
576_A579_A0.8330.96
314_K334_N0.8330.96
499_L515_Y0.8310.96
255_R259_L0.8290.96
279_R285_R0.8230.96
584_K605_Q0.8230.96
290_A295_D0.8220.96
210_D230_N0.8220.96
523_Q527_N0.8210.96
512_L515_Y0.8210.96
596_K600_T0.8190.96
285_R288_L0.8180.96
147_V159_N0.8180.96
564_I567_L0.8160.96
304_A477_E0.8150.96
501_H504_K0.8150.96
512_L516_Q0.8140.96
427_E430_R0.8130.96
590_L593_Q0.8110.96
600_T603_L0.8110.96
220_E225_F0.8080.96
250_E254_E0.8070.96
395_I410_L0.8050.96
398_L442_A0.8040.96
258_H261_S0.8030.96
278_S282_M0.7990.96
140_N143_L0.7980.95
168_S195_Y0.7960.95
563_E570_E0.7950.95
275_Q280_I0.7940.95
140_N144_E0.7940.95
474_I492_S0.7920.95
515_Y518_W0.7920.95
411_R424_V0.7910.95
134_H143_L0.7880.95
308_L451_L0.7850.95
278_S287_E0.7850.95
415_G420_Q0.7850.95
463_L467_Q0.7840.95
499_L519_L0.7810.95
583_E586_G0.7790.95
273_A280_I0.7790.95
275_Q282_M0.7780.95
389_R397_H0.7780.95
508_F518_W0.7770.95
519_L523_Q0.7750.95
529_T532_A0.7700.95
227_Y237_Q0.7680.94
316_E370_G0.7660.94
209_L234_F0.7640.94
415_G419_F0.7630.94
399_A410_L0.7630.94
139_S143_L0.7610.94
555_A562_K0.7580.94
454_L480_L0.7560.94
127_S131_S0.7560.94
313_L335_L0.7550.94
275_Q279_R0.7550.94
278_S289_I0.7540.94
277_Q287_E0.7540.94
471_E475_E0.7520.94
484_S489_L0.7520.94
121_D128_R0.7510.94
573_K576_A0.7500.94
540_A545_D0.7490.94
125_I129_A0.7490.94
309_P372_A0.7490.94
136_L161_A0.7470.94
527_N530_D0.7440.93
415_G421_G0.7430.93
306_E376_K0.7430.93
319_S326_I0.7420.93
218_H241_R0.7420.93
597_A600_T0.7380.93
593_Q596_K0.7380.93
309_P312_L0.7370.93
396_Q400_R0.7360.93
378_G444_I0.7350.93
585_L591_Y0.7340.93
272_K280_I0.7340.93
528_Q531_E0.7310.93
268_A273_A0.7310.93
574_L612_G0.7300.93
563_E566_R0.7280.93
531_E534_K0.7270.93
590_L599_L0.7260.93
547_K553_L0.7250.93
542_A546_Q0.7250.93
163_A171_L0.7240.93
571_M616_C0.7230.92
203_S209_L0.7220.92
360_G371_L0.7220.92
264_D269_K0.7210.92
105_N109_A0.7180.92
317_K366_S0.7170.92
575_N579_A0.7150.92
560_L568_E0.7130.92
541_Q545_D0.7120.92
357_L363_A0.7110.92
593_Q598_E0.7090.92
216_I230_N0.7090.92
110_I117_L0.7070.92
138_F150_F0.7060.92
344_L497_L0.7050.92
591_Y599_L0.7050.92
329_D366_S0.7040.91
556_Q559_P0.7040.91
108_H111_A0.7040.91
257_A261_S0.7030.91
581_A585_L0.7020.91
553_L557_T0.6990.91
518_W521_D0.6980.91
259_L262_Y0.6970.91
620_W624_Q0.6960.91
574_L577_Q0.6960.91
281_K286_M0.6960.91
262_Y279_R0.6940.91
270_A277_Q0.6930.91
339_S495_D0.6930.91
563_E623_A0.6920.91
308_L312_L0.6910.91
329_D502_D0.6900.91
577_Q612_G0.6900.91
525_Q529_T0.6900.91
276_A286_M0.6900.91
596_K599_L0.6900.91
290_A294_V0.6890.91
210_D488_H0.6890.91
335_L498_Y0.6860.90
293_H297_P0.6850.90
588_S592_D0.6850.90
613_L616_C0.6840.90
543_R551_A0.6830.90
272_K277_Q0.6780.90
358_L481_V0.6770.90
267_R273_A0.6770.90
354_L358_L0.6770.90
290_A293_H0.6750.90
110_I114_H0.6730.90
130_A140_N0.6700.89
273_A276_A0.6700.89
613_L617_E0.6690.89
522_V526_E0.6680.89
524_K527_N0.6680.89
355_I453_L0.6670.89
312_L479_A0.6670.89
277_Q284_E0.6660.89
292_A295_D0.6640.89
543_R546_Q0.6620.89
322_Y326_I0.6610.89
248_M289_I0.6600.89
278_S284_E0.6590.89
114_H118_D0.6590.89
393_S427_E0.6580.89
195_Y199_L0.6570.88
275_Q289_I0.6570.88
335_L479_A0.6560.88
568_E624_Q0.6540.88
422_D425_T0.6530.88
453_L483_V0.6530.88
263_I267_R0.6520.88
281_K287_E0.6520.88
118_D122_A0.6520.88
542_A551_A0.6520.88
510_G515_Y0.6500.88
411_R421_G0.6500.88
555_A559_P0.6490.88
247_A250_E0.6470.88
262_Y271_T0.6460.88
413_Y416_G0.6450.88
291_P294_V0.6450.88
500_V505_V0.6440.87
134_H140_N0.6440.87
405_E446_W0.6420.87
274_K281_K0.6410.87
540_A543_R0.6410.87
241_R244_Q0.6400.87
321_G357_L0.6370.87
402_A405_E0.6370.87
124_S127_S0.6350.87
413_Y419_F0.6350.87
266_F280_I0.6330.87
556_Q563_E0.6330.87
377_L451_L0.6310.86
320_A328_L0.6300.86
125_I165_I0.6290.86
130_A143_L0.6280.86
251_S255_R0.6270.86
268_A280_I0.6260.86
521_D525_Q0.6260.86
581_A584_K0.6250.86
319_S328_L0.6240.86
311_P314_K0.6240.86
276_A282_M0.6240.86
255_R282_M0.6230.86
281_K289_I0.6230.86
349_A500_V0.6220.86
539_S542_A0.6210.85
395_I425_T0.6200.85
199_L212_I0.6200.85
256_V263_I0.6200.85
405_E410_L0.6190.85
547_K554_R0.6180.85
320_A323_G0.6170.85
277_Q282_M0.6160.85
372_A450_N0.6130.85
568_E581_A0.6130.85
294_V297_P0.6130.85
361_E387_Y0.6130.85
358_L369_I0.6120.85
335_L451_L0.6120.85
530_D533_P0.6120.85
270_A274_K0.6120.85
268_A277_Q0.6120.85
556_Q564_I0.6110.85
262_Y266_F0.6110.85
276_A289_I0.6100.84
607_A614_E0.6090.84
571_M579_A0.6080.84
118_D123_W0.6070.84
131_S135_G0.6050.84
182_L186_I0.6050.84
252_Q256_V0.6050.84
413_Y446_W0.6050.84
309_P373_K0.6050.84
117_L121_D0.6040.84
338_G479_A0.6040.84
596_K603_L0.6040.84
605_Q612_G0.6030.84
179_H442_A0.6020.84
189_E487_R0.6020.84
142_Q150_F0.6020.84
539_S543_R0.6010.84
170_L200_I0.6010.84
551_A559_P0.6000.83
269_K280_I0.6000.83
393_S397_H0.5990.83
505_V508_F0.5990.83
216_I220_E0.5970.83
567_L575_N0.5970.83
266_F277_Q0.5950.83
413_Y442_A0.5950.83
265_R268_A0.5950.83
410_L419_F0.5950.83
252_Q263_I0.5930.83
555_A565_A0.5930.83
107_G111_A0.5930.83
520_S523_Q0.5920.83
263_I284_E0.5920.83
145_R150_F0.5910.83
201_L212_I0.5910.83
236_V239_A0.5910.83
504_K508_F0.5910.83
526_E530_D0.5900.82
498_Y507_P0.5900.82
276_A284_E0.5900.82
272_K278_S0.5890.82
358_L371_L0.5890.82
598_E605_Q0.5890.82
508_F514_D0.5880.82
395_I424_V0.5880.82
405_E408_Q0.5880.82
273_A281_K0.5880.82
266_F275_Q0.5870.82
113_I116_K0.5850.82
324_D327_I0.5830.82
533_P546_Q0.5830.82
247_A251_S0.5820.82
359_A377_L0.5820.82
538_N541_Q0.5800.81
503_R507_P0.5800.81
554_R559_P0.5790.81
568_E574_L0.5780.81
235_E467_Q0.5770.81
317_K320_A0.5750.81
312_L450_N0.5750.81
380_F437_A0.5750.81
600_T607_A0.5740.81
260_Q263_I0.5740.81
267_R276_A0.5740.81
390_A436_K0.5730.81
583_E605_Q0.5720.81
274_K279_R0.5700.80
529_T533_P0.5680.80
277_Q289_I0.5680.80
614_E625_E0.5680.80
545_D580_Q0.5670.80
321_G327_I0.5670.80
318_V328_L0.5660.80
275_Q286_M0.5650.80
567_L570_E0.5640.80
110_I118_D0.5640.80
516_Q520_S0.5620.79
543_R550_E0.5620.79
577_Q608_S0.5610.79
578_L581_A0.5610.79
192_L212_I0.5610.79
564_I568_E0.5600.79
331_I505_V0.5590.79
225_F234_F0.5570.79
521_D524_K0.5570.79
537_A540_A0.5570.79
371_L377_L0.5570.79
284_E287_E0.5560.79
265_R271_T0.5560.79
265_R273_A0.5560.79
570_E577_Q0.5530.78
230_N237_Q0.5520.78
272_K275_Q0.5520.78
101_A106_D0.5520.78
246_Q249_Y0.5500.78
343_L481_V0.5500.78
245_Q289_I0.5480.78
551_A557_T0.5480.78
524_K530_D0.5470.78
132_L191_W0.5470.78
256_V260_Q0.5470.78
590_L598_E0.5460.77
542_A615_E0.5460.77
387_Y440_V0.5450.77
559_P565_A0.5440.77
262_Y270_A0.5440.77
232_S236_V0.5430.77
398_L410_L0.5420.77
260_Q283_L0.5420.77
298_F302_F0.5410.77
136_L187_W0.5410.77
271_T274_K0.5400.77
554_R557_T0.5400.77
575_N578_L0.5400.77
262_Y269_K0.5390.76
237_Q244_Q0.5390.76
247_A439_L0.5380.76
303_R448_R0.5380.76
581_A590_L0.5380.76
408_Q416_G0.5380.76
309_P489_L0.5370.76
113_I117_L0.5370.76
541_Q546_Q0.5370.76
359_A379_Y0.5360.76
563_E616_C0.5360.76
272_K276_A0.5350.76
245_Q248_M0.5340.76
147_V155_R0.5340.76
533_P537_A0.5340.76
501_H519_L0.5320.76
271_T276_A0.5320.76
262_Y268_A0.5310.75
274_K283_L0.5310.75
544_K611_S0.5310.75
228_T233_S0.5310.75
207_D491_R0.5300.75
117_L123_W0.5290.75
530_D534_K0.5290.75
245_Q291_P0.5290.75
544_K550_E0.5280.75
568_E588_S0.5270.75
488_H492_S0.5260.75
560_L565_A0.5250.75
129_A165_I0.5240.74
557_T562_K0.5240.74
580_Q605_Q0.5240.74
172_L617_E0.5230.74
321_G366_S0.5230.74
267_R285_R0.5220.74
420_Q423_K0.5210.74
360_G363_A0.5210.74
531_E535_E0.5200.74
262_Y273_A0.5190.74
538_N543_R0.5190.74
280_I286_M0.5190.74
534_K546_Q0.5170.74
193_K212_I0.5170.74
429_R439_L0.5170.74
611_S618_M0.5160.73
268_A276_A0.5160.73
266_F271_T0.5160.73
265_R269_K0.5150.73
606_Q613_L0.5140.73
501_H508_F0.5140.73
534_K537_A0.5140.73
259_L279_R0.5130.73
164_L187_W0.5110.73
251_S254_E0.5100.73
258_H282_M0.5090.72
218_H227_Y0.5080.72
269_K278_S0.5080.72
536_N543_R0.5080.72
542_A548_R0.5080.72
440_V443_L0.5070.72
534_K544_K0.5070.72
291_P296_N0.5060.72
154_W380_F0.5050.72
498_Y505_V0.5050.72
139_S145_R0.5030.71
526_E529_T0.5030.71
543_R547_K0.5030.71
282_M285_R0.5020.71
206_R470_T0.5000.71
273_A278_S0.5000.71
277_Q286_M0.5000.71
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4finA 2 0.8179 100 0.422 Contact Map
2iw3A 2 0.6719 100 0.492 Contact Map
4q9hA 1 0.7708 100 0.505 Contact Map
4f4cA 1 0.73 100 0.51 Contact Map
3bk7A 1 0.7802 100 0.536 Contact Map
1yqtA 1 0.7818 100 0.541 Contact Map
3ozxA 1 0.7739 100 0.553 Contact Map
3j16B 1 0.8006 100 0.561 Contact Map
3ux8A 2 0.6546 100 0.595 Contact Map
2vf7A 2 0.7394 100 0.642 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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