CLPB - ECOLI - GREMLIN Contacts

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CLPB - Chaperone protein ClpB

UniProt:	P63284	Sequences: MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRGDNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQELHHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDEALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAVQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10157
Length:	857 (846)
Sequences:	3836 (1821)
Seq/√Len:	62.6

ECOLI - CLPB CLPA
BACSU - CLPC CLPE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
170_E	174_Q	6.853	1.00
776_Q	800_L	5.305	1.00
167_D	236_R	5.150	1.00
796_S	847_E	5.125	1.00
419_I	448_L	4.684	1.00
772_A	801_K	4.624	1.00
165_T	238_L	4.403	1.00
508_E	512_Q	4.401	1.00
490_R	502_Q	4.080	1.00
412_L	455_Y	4.074	1.00
243_G	298_M	3.851	1.00
26_N	68_L	3.773	1.00
716_M	757_I	3.618	1.00
567_H	574_N	3.613	1.00
768_E	805_E	3.554	1.00
423_K	452_E	3.550	1.00
832_Q	837_E	3.520	1.00
565_E	568_H	3.511	1.00
426_Q	445_N	3.463	1.00
798_E	847_E	3.460	1.00
561_R	564_Q	3.439	1.00
496_A	500_E	3.351	1.00
166_I	171_R	3.258	1.00
346_T	374_A	3.253	1.00
780_K	783_Y	3.106	1.00
479_L	506_I	3.072	1.00
159_Q	162_K	2.921	1.00
497_R	500_E	2.893	1.00
264_N	268_K	2.848	1.00
230_E	233_K	2.833	1.00
267_A	307_E	2.822	1.00
471_G	512_Q	2.809	1.00
486_I	506_I	2.767	1.00
482_A	506_I	2.741	1.00
446_E	450_D	2.725	1.00
343_V	374_A	2.682	1.00
36_S	65_N	2.672	1.00
90_V	114_A	2.593	1.00
602_L	757_I	2.590	1.00
500_E	505_K	2.572	1.00
505_K	508_E	2.515	1.00
50_L	55_I	2.495	1.00
488_Q	492_V	2.407	1.00
427_Q	430_M	2.392	1.00
475_I	513_L	2.392	1.00
353_L	356_R	2.365	1.00
27_Q	74_V	2.329	1.00
478_E	505_K	2.309	1.00
693_V	714_V	2.271	1.00
162_K	170_E	2.257	1.00
463_K	467_A	2.255	1.00
567_H	577_V	2.241	1.00
479_L	513_L	2.238	1.00
582_N	831_Q	2.236	1.00
602_L	679_V	2.231	1.00
720_L	745_V	2.191	1.00
408_K	416_D	2.187	1.00
796_S	845_R	2.184	1.00
482_A	501_L	2.158	1.00
510_E	514_E	2.152	1.00
690_L	693_V	2.131	1.00
485_A	497_R	2.126	1.00
321_Q	658_E	2.108	1.00
63_D	128_A	2.090	1.00
481_Q	485_A	2.080	1.00
791_Y	844_I	2.075	1.00
339_A	669_R	2.069	1.00
132_T	135_N	2.059	1.00
514_E	518_Q	2.058	1.00
426_Q	441_L	2.048	1.00
434_D	437_S	2.032	1.00
782_L	821_I	2.016	1.00
402_R	406_D	2.014	1.00
343_V	378_H	2.014	1.00
337_F	669_R	2.014	1.00
794_H	845_R	2.013	1.00
644_S	647_V	2.002	1.00
483_K	510_E	2.000	1.00
459_E	463_K	1.999	1.00
52_S	142_Q	1.991	1.00
577_V	614_L	1.990	1.00
393_L	540_L	1.979	1.00
563_E	585_R	1.978	1.00
425_E	440_R	1.973	1.00
250_K	254_E	1.964	1.00
167_D	170_E	1.958	1.00
477_A	481_Q	1.936	1.00
587_S	592_A	1.925	1.00
600_S	694_L	1.925	1.00
482_A	505_K	1.924	1.00
234_G	272_N	1.924	1.00
563_E	578_D	1.913	1.00
745_V	754_I	1.908	1.00
640_K	685_D	1.892	1.00
203_V	280_L	1.887	1.00
416_D	459_E	1.876	1.00
641_H	650_P	1.871	1.00
138_Q	142_Q	1.858	1.00
439_K	443_M	1.843	1.00
85_Q	89_R	1.843	1.00
173_E	236_R	1.842	1.00
839_V	842_K	1.840	1.00
562_M	621_F	1.840	1.00
342_S	345_D	1.836	1.00
372_A	533_D	1.833	1.00
453_R	456_S	1.823	1.00
34_L	87_L	1.822	1.00
10_F	111_F	1.822	1.00
569_R	613_E	1.819	1.00
394_I	536_I	1.812	1.00
742_L	812_Y	1.806	1.00
453_R	457_E	1.803	1.00
430_M	445_N	1.784	1.00
641_H	644_S	1.783	1.00
422_L	444_L	1.783	1.00
724_L	744_V	1.778	1.00
474_T	478_E	1.775	1.00
478_E	512_Q	1.772	1.00
280_L	323_I	1.768	1.00
242_M	245_L	1.767	1.00
838_L	844_I	1.766	1.00
343_V	375_T	1.754	0.99
794_H	843_V	1.743	0.99
223_I	237_V	1.737	0.99
767_G	770_H	1.733	0.99
825_I	846_L	1.731	0.99
39_L	64_I	1.727	0.99
104_N	150_N	1.708	0.99
511_K	515_A	1.703	0.99
792_E	843_V	1.699	0.99
496_A	499_S	1.696	0.99
226_G	233_K	1.694	0.99
151_D	157_Q	1.682	0.99
97_L	133_T	1.680	0.99
482_A	509_L	1.679	0.99
511_K	514_E	1.678	0.99
24_H	69_N	1.672	0.99
40_N	61_R	1.669	0.99
575_E	738_K	1.665	0.99
359_L	362_H	1.662	0.99
475_I	509_L	1.662	0.99
514_E	517_T	1.658	0.99
779_L	795_I	1.654	0.99
83_P	87_L	1.646	0.99
90_V	115_A	1.634	0.99
474_T	477_A	1.628	0.99
190_T	336_V	1.627	0.99
284_V	329_L	1.622	0.99
67_A	125_I	1.617	0.99
30_E	84_S	1.617	0.99
829_L	844_I	1.616	0.99
553_E	561_R	1.607	0.99
418_R	447_E	1.607	0.99
647_V	689_I	1.596	0.99
482_A	486_I	1.592	0.99
411_E	454_Q	1.589	0.99
638_M	642_S	1.588	0.99
408_K	459_E	1.586	0.99
720_L	744_V	1.579	0.99
775_A	804_S	1.575	0.99
55_I	60_L	1.574	0.99
449_S	453_R	1.573	0.99
41_Q	44_G	1.573	0.99
177_L	221_Q	1.572	0.99
569_R	620_N	1.570	0.99
123_A	127_K	1.563	0.99
370_I	394_I	1.551	0.99
133_T	137_T	1.549	0.99
264_N	267_A	1.548	0.99
102_G	148_S	1.545	0.99
742_L	762_V	1.544	0.99
666_V	709_F	1.537	0.99
698_R	706_T	1.533	0.99
802_L	848_V	1.531	0.99
222_R	417_R	1.529	0.99
9_K	12_L	1.528	0.99
693_V	699_L	1.526	0.99
628_A	669_R	1.524	0.99
65_N	69_N	1.517	0.98
569_R	626_D	1.512	0.98
36_S	64_I	1.507	0.98
776_Q	797_D	1.506	0.98
478_E	481_Q	1.500	0.98
48_P	159_Q	1.499	0.98
160_A	261_G	1.499	0.98
63_D	66_Q	1.494	0.98
742_L	745_V	1.490	0.98
789_R	840_P	1.488	0.98
638_M	688_N	1.487	0.98
516_A	520_E	1.480	0.98
97_L	100_K	1.478	0.98
280_L	312_G	1.473	0.98
482_A	485_A	1.471	0.98
807_G	817_L	1.464	0.98
13_A	38_L	1.460	0.98
171_R	176_K	1.458	0.98
107_S	149_V	1.457	0.98
720_L	748_N	1.454	0.98
723_D	744_V	1.449	0.98
541_A	548_V	1.446	0.98
31_P	87_L	1.442	0.98
499_S	502_Q	1.432	0.98
734_Y	737_M	1.428	0.98
778_Q	781_R	1.426	0.98
637_F	661_Y	1.425	0.98
515_A	519_L	1.422	0.98
153_G	156_D	1.421	0.98
124_D	128_A	1.420	0.98
231_G	406_D	1.418	0.98
450_D	454_Q	1.417	0.98
508_E	511_K	1.414	0.98
144_R	149_V	1.414	0.98
26_N	71_L	1.413	0.98
561_R	565_E	1.413	0.98
364_Q	530_K	1.408	0.98
467_A	471_G	1.399	0.97
736_H	740_L	1.398	0.97
24_H	73_Q	1.397	0.97
36_S	61_R	1.396	0.97
803_L	820_A	1.394	0.97
782_L	826_E	1.384	0.97
733_D	736_H	1.383	0.97
415_L	451_K	1.381	0.97
97_L	114_A	1.377	0.97
32_L	67_A	1.377	0.97
630_V	666_V	1.372	0.97
435_E	439_K	1.372	0.97
321_Q	657_E	1.371	0.97
516_A	519_L	1.367	0.97
569_R	617_A	1.363	0.97
848_V	851_D	1.361	0.97
582_N	827_N	1.361	0.97
470_S	474_T	1.360	0.97
131_A	136_I	1.358	0.97
723_D	727_E	1.358	0.97
36_S	40_N	1.355	0.97
615_C	715_I	1.354	0.97
602_L	745_V	1.350	0.97
802_L	806_N	1.349	0.97
806_N	820_A	1.342	0.97
432_E	437_S	1.340	0.97
100_K	137_T	1.335	0.97
744_V	747_H	1.335	0.97
632_I	646_L	1.333	0.97
820_A	824_Q	1.332	0.96
725_I	737_M	1.332	0.96
471_G	516_A	1.331	0.96
437_S	440_R	1.329	0.96
207_E	316_L	1.328	0.96
242_M	283_M	1.327	0.96
795_I	799_A	1.321	0.96
177_L	180_V	1.318	0.96
50_L	60_L	1.318	0.96
168_L	239_A	1.317	0.96
571_I	777_I	1.316	0.96
801_K	805_E	1.311	0.96
528_R	532_T	1.308	0.96
638_M	685_D	1.301	0.96
594_P	785_R	1.294	0.96
67_A	121_T	1.290	0.96
13_A	41_Q	1.289	0.96
227_E	417_R	1.289	0.96
20_L	24_H	1.286	0.96
479_L	509_L	1.279	0.96
630_V	672_S	1.279	0.96
469_L	527_L	1.278	0.96
96_K	99_Q	1.275	0.95
423_K	448_L	1.275	0.95
775_A	800_L	1.275	0.95
245_L	262_V	1.273	0.95
107_S	154_A	1.272	0.95
18_Q	29_I	1.266	0.95
452_E	456_S	1.263	0.95
242_M	246_V	1.259	0.95
773_S	776_Q	1.258	0.95
6_L	10_F	1.255	0.95
791_Y	838_L	1.255	0.95
764_H	770_H	1.254	0.95
283_M	296_G	1.253	0.95
565_E	617_A	1.251	0.95
798_E	801_K	1.249	0.95
348_A	421_Q	1.248	0.95
24_H	68_L	1.242	0.95
57_A	61_R	1.242	0.95
739_E	743_G	1.242	0.95
637_F	645_R	1.241	0.95
795_I	800_L	1.238	0.95
93_L	96_K	1.235	0.95
575_E	764_H	1.233	0.95
20_L	37_A	1.231	0.95
738_K	762_V	1.229	0.94
167_D	238_L	1.229	0.94
56_N	59_Q	1.224	0.94
494_D	497_R	1.224	0.94
499_S	503_Y	1.223	0.94
439_K	790_G	1.222	0.94
480_E	484_I	1.220	0.94
419_I	451_K	1.218	0.94
790_G	840_P	1.216	0.94
592_A	598_I	1.216	0.94
44_G	47_S	1.214	0.94
484_I	488_Q	1.209	0.94
166_I	239_A	1.209	0.94
31_P	90_V	1.208	0.94
455_Y	459_E	1.204	0.94
557_E	561_R	1.203	0.94
564_Q	567_H	1.199	0.94
585_R	834_L	1.198	0.94
617_A	620_N	1.197	0.94
117_E	133_T	1.195	0.94
738_K	742_L	1.193	0.94
362_H	473_Q	1.190	0.93
372_A	375_T	1.190	0.93
498_M	502_Q	1.190	0.93
768_E	801_K	1.190	0.93
416_D	455_Y	1.187	0.93
124_D	127_K	1.185	0.93
350_L	373_A	1.183	0.93
735_A	739_E	1.179	0.93
566_L	617_A	1.175	0.93
14_L	91_L	1.170	0.93
193_V	336_V	1.160	0.93
23_G	96_K	1.154	0.92
772_A	797_D	1.153	0.92
563_E	581_S	1.152	0.92
366_T	532_T	1.151	0.92
728_R	737_M	1.147	0.92
423_K	426_Q	1.144	0.92
145_G	149_V	1.142	0.92
560_L	834_L	1.140	0.92
779_L	783_Y	1.139	0.92
775_A	821_I	1.137	0.92
565_E	621_F	1.137	0.92
49_L	143_M	1.135	0.92
560_L	831_Q	1.134	0.92
784_K	787_E	1.132	0.92
438_K	441_L	1.132	0.92
160_A	265_D	1.132	0.92
419_I	455_Y	1.131	0.92
199_K	392_D	1.130	0.92
242_M	266_L	1.129	0.92
826_E	830_A	1.128	0.92
263_L	302_A	1.128	0.92
486_I	502_Q	1.126	0.91
450_D	453_R	1.126	0.91
67_A	70_R	1.124	0.91
121_T	124_D	1.122	0.91
134_A	138_Q	1.119	0.91
185_E	414_R	1.118	0.91
787_E	792_E	1.117	0.91
745_V	760_V	1.116	0.91
442_D	445_N	1.115	0.91
266_L	273_V	1.113	0.91
585_R	827_N	1.110	0.91
93_L	117_E	1.109	0.91
135_N	138_Q	1.106	0.91
32_L	71_L	1.099	0.90
495_L	504_G	1.098	0.90
221_Q	225_N	1.098	0.90
137_T	140_I	1.098	0.90
448_L	452_E	1.096	0.90
442_D	446_E	1.095	0.90
13_A	34_L	1.091	0.90
603_F	715_I	1.089	0.90
53_A	131_A	1.088	0.90
464_A	467_A	1.088	0.90
562_M	581_S	1.083	0.90
45_S	107_S	1.081	0.90
429_L	432_E	1.081	0.90
381_I	540_L	1.080	0.90
578_D	582_N	1.077	0.90
461_E	465_E	1.074	0.89
222_R	227_E	1.073	0.89
779_L	825_I	1.071	0.89
36_S	68_L	1.063	0.89
8_N	152_Q	1.059	0.89
821_I	825_I	1.056	0.89
98_A	106_I	1.055	0.89
18_Q	81_V	1.053	0.88
806_N	824_Q	1.052	0.88
118_S	123_A	1.052	0.88
208_P	385_Q	1.051	0.88
35_M	122_L	1.051	0.88
192_Q	400_S	1.049	0.88
831_Q	835_S	1.048	0.88
796_S	799_A	1.048	0.88
105_F	152_Q	1.048	0.88
6_L	91_L	1.046	0.88
604_L	718_S	1.045	0.88
469_L	476_K	1.043	0.88
197_R	591_L	1.041	0.88
290_D	321_Q	1.040	0.88
783_Y	793_I	1.039	0.88
785_R	826_E	1.039	0.88
29_I	83_P	1.038	0.88
798_E	848_V	1.034	0.88
559_L	585_R	1.030	0.87
832_Q	835_S	1.030	0.87
126_L	129_A	1.030	0.87
426_Q	444_L	1.029	0.87
776_Q	783_Y	1.025	0.87
377_S	389_K	1.025	0.87
368_P	533_D	1.020	0.87
509_L	517_T	1.015	0.87
486_I	501_L	1.013	0.86
517_T	521_G	1.011	0.86
227_E	413_D	1.010	0.86
568_H	780_K	1.009	0.86
30_E	86_D	1.008	0.86
510_E	517_T	1.008	0.86
594_P	788_E	1.008	0.86
734_Y	764_H	1.005	0.86
603_F	763_F	1.004	0.86
676_L	693_V	1.003	0.86
16_D	37_A	1.001	0.86
63_D	129_A	0.999	0.86
468_S	472_T	0.997	0.86
471_G	475_I	0.995	0.85
772_A	800_L	0.995	0.85
807_G	820_A	0.994	0.85
8_N	153_G	0.993	0.85
38_L	108_S	0.993	0.85
269_Q	273_V	0.990	0.85
685_D	688_N	0.990	0.85
501_L	505_K	0.983	0.85
7_T	107_S	0.983	0.85
101_R	110_L	0.983	0.85
60_L	125_I	0.983	0.85
457_E	461_E	0.982	0.85
205_I	335_K	0.981	0.85
485_A	488_Q	0.981	0.85
438_K	442_D	0.980	0.85
97_L	137_T	0.979	0.84
366_T	530_K	0.978	0.84
740_L	744_V	0.978	0.84
679_V	716_M	0.976	0.84
120_G	123_A	0.976	0.84
221_Q	224_I	0.975	0.84
540_L	548_V	0.972	0.84
249_A	262_V	0.972	0.84
246_V	298_M	0.972	0.84
27_Q	77_T	0.971	0.84
585_R	831_Q	0.971	0.84
795_I	846_L	0.969	0.84
405_I	469_L	0.967	0.84
204_L	338_V	0.966	0.84
12_L	16_D	0.966	0.84
140_I	147_E	0.965	0.84
46_V	136_I	0.964	0.84
94_C	111_F	0.956	0.83
643_V	686_V	0.956	0.83
242_M	282_T	0.956	0.83
418_R	421_Q	0.953	0.83
252_R	290_D	0.953	0.83
736_H	739_E	0.953	0.83
46_V	112_V	0.953	0.83
778_Q	818_K	0.951	0.83
528_R	535_E	0.951	0.83
32_L	86_D	0.951	0.83
6_L	111_F	0.951	0.83
771_I	804_S	0.950	0.83
513_L	517_T	0.950	0.83
424_L	427_Q	0.949	0.83
410_E	415_L	0.949	0.83
162_K	165_T	0.948	0.83
317_D	321_Q	0.947	0.82
289_A	293_M	0.947	0.82
679_V	757_I	0.943	0.82
316_L	703_Q	0.943	0.82
797_D	801_K	0.943	0.82
595_N	627_E	0.942	0.82
454_Q	457_E	0.939	0.82
802_L	820_A	0.939	0.82
779_L	821_I	0.938	0.82
170_E	173_E	0.936	0.82
461_E	524_M	0.932	0.81
479_L	482_A	0.931	0.81
130_G	136_I	0.931	0.81
39_L	60_L	0.931	0.81
116_L	136_I	0.928	0.81
20_L	23_G	0.928	0.81
16_D	19_S	0.928	0.81
6_L	95_D	0.927	0.81
177_L	570_V	0.926	0.81
28_F	82_Q	0.926	0.81
320_R	649_A	0.924	0.81
500_E	504_G	0.924	0.81
776_Q	795_I	0.923	0.81
412_L	526_L	0.922	0.81
458_L	526_L	0.920	0.81
288_K	321_Q	0.919	0.81
101_R	137_T	0.918	0.80
106_I	111_F	0.916	0.80
28_F	84_S	0.912	0.80
66_Q	70_R	0.911	0.80
130_G	133_T	0.907	0.80
497_R	505_K	0.905	0.80
169_T	238_L	0.904	0.79
515_A	518_Q	0.901	0.79
639_E	650_P	0.901	0.79
645_R	700_T	0.899	0.79
772_A	776_Q	0.898	0.79
415_L	455_Y	0.898	0.79
67_A	124_D	0.895	0.79
475_I	512_Q	0.892	0.79
61_R	65_N	0.892	0.79
139_A	142_Q	0.891	0.78
280_L	311_V	0.890	0.78
490_R	493_G	0.888	0.78
236_R	272_N	0.886	0.78
419_I	452_E	0.886	0.78
679_V	745_V	0.886	0.78
423_K	427_Q	0.886	0.78
509_L	512_Q	0.884	0.78
104_N	148_S	0.881	0.78
8_N	12_L	0.880	0.78
580_V	603_F	0.878	0.77
35_M	112_V	0.875	0.77
443_M	446_E	0.875	0.77
566_L	570_V	0.872	0.77
632_I	644_S	0.871	0.77
400_S	404_Q	0.869	0.77
498_M	507_P	0.869	0.77
443_M	676_L	0.869	0.77
437_S	441_L	0.867	0.77
643_V	689_I	0.866	0.76
132_T	136_I	0.866	0.76
657_E	676_L	0.862	0.76
355_E	483_K	0.862	0.76
666_V	712_T	0.861	0.76
91_L	106_I	0.861	0.76
471_G	474_T	0.860	0.76
495_L	502_Q	0.859	0.76
136_I	140_I	0.856	0.76
495_L	499_S	0.856	0.76
135_N	139_A	0.855	0.76
483_K	506_I	0.855	0.76
197_R	357_Y	0.850	0.75
143_M	149_V	0.848	0.75
350_L	390_A	0.848	0.75
203_V	323_I	0.847	0.75
476_K	517_T	0.847	0.75
189_R	192_Q	0.845	0.75
838_L	842_K	0.845	0.75
240_L	262_V	0.844	0.75
336_V	684_P	0.843	0.74
650_P	657_E	0.843	0.74
416_D	420_I	0.842	0.74
38_L	44_G	0.841	0.74
378_H	385_Q	0.839	0.74
783_Y	787_E	0.837	0.74
172_A	197_R	0.836	0.74
772_A	804_S	0.834	0.74
8_N	11_Q	0.834	0.74
10_F	108_S	0.834	0.74
26_N	33_H	0.834	0.74
208_P	327_A	0.833	0.74
32_L	121_T	0.829	0.73
10_F	106_I	0.828	0.73
377_S	386_L	0.828	0.73
143_M	147_E	0.827	0.73
249_A	322_Y	0.826	0.73
169_T	172_A	0.826	0.73
289_A	322_Y	0.825	0.73
293_M	298_M	0.825	0.73
450_D	483_K	0.824	0.73
640_K	647_V	0.824	0.73
506_I	513_L	0.821	0.73
55_I	131_A	0.821	0.73
832_Q	838_L	0.821	0.73
354_K	431_K	0.819	0.72
532_T	535_E	0.815	0.72
51_T	57_A	0.813	0.72
593_D	596_R	0.813	0.72
277_I	310_C	0.812	0.72
178_D	197_R	0.812	0.72
440_R	447_E	0.812	0.72
169_T	224_I	0.811	0.72
420_I	423_K	0.811	0.72
242_M	298_M	0.811	0.72
354_K	370_I	0.809	0.71
629_M	673_V	0.809	0.71
192_Q	834_L	0.809	0.71
309_H	535_E	0.808	0.71
347_I	370_I	0.806	0.71
541_A	550_R	0.803	0.71
263_L	298_M	0.802	0.71
783_Y	795_I	0.802	0.71
95_D	99_Q	0.801	0.71
729_F	765_P	0.801	0.71
724_L	740_L	0.801	0.71
230_E	406_D	0.801	0.71
460_E	464_A	0.800	0.71
803_L	807_G	0.799	0.70
84_S	87_L	0.799	0.70
188_R	413_D	0.797	0.70
125_I	129_A	0.796	0.70
721_G	741_V	0.795	0.70
141_E	146_G	0.794	0.70
172_A	177_L	0.794	0.70
126_L	130_G	0.793	0.70
743_G	747_H	0.793	0.70
538_E	549_S	0.792	0.70
320_R	703_Q	0.791	0.70
95_D	98_A	0.791	0.70
753_F	757_I	0.791	0.70
426_Q	448_L	0.789	0.70
691_L	752_E	0.788	0.69
737_M	764_H	0.787	0.69
530_K	535_E	0.786	0.69
410_E	414_R	0.785	0.69
151_D	257_E	0.785	0.69
746_S	812_Y	0.784	0.69
30_E	71_L	0.784	0.69
419_I	423_K	0.783	0.69
11_Q	152_Q	0.783	0.69
827_N	831_Q	0.782	0.69
245_L	275_L	0.782	0.69
216_V	261_G	0.782	0.69
378_H	674_I	0.781	0.69
767_G	808_Y	0.781	0.69
327_A	382_A	0.781	0.69
400_S	539_V	0.780	0.69
780_K	784_K	0.779	0.69
197_R	699_L	0.779	0.69
432_E	440_R	0.779	0.69
728_R	740_L	0.778	0.68
189_R	396_E	0.775	0.68
414_R	418_R	0.775	0.68
35_M	64_I	0.775	0.68
93_L	97_L	0.775	0.68
10_F	34_L	0.774	0.68
62_T	66_Q	0.772	0.68
237_V	269_Q	0.772	0.68
27_Q	82_Q	0.772	0.68
493_G	496_A	0.770	0.68
799_A	848_V	0.770	0.68
118_S	127_K	0.769	0.68
496_A	505_K	0.768	0.67
97_L	101_R	0.768	0.67
639_E	644_S	0.768	0.67
483_K	487_E	0.765	0.67
10_F	25_D	0.765	0.67
604_L	745_V	0.765	0.67
486_I	499_S	0.765	0.67
559_L	588_R	0.764	0.67
103_D	144_R	0.763	0.67
21_A	26_N	0.763	0.67
116_L	669_R	0.762	0.67
46_V	116_L	0.762	0.67
378_H	627_E	0.762	0.67
122_L	126_L	0.761	0.67
11_Q	15_A	0.761	0.67
741_V	745_V	0.759	0.67
415_L	454_Q	0.759	0.67
642_S	760_V	0.758	0.66
50_L	57_A	0.758	0.66
97_L	140_I	0.757	0.66
559_L	834_L	0.756	0.66
647_V	812_Y	0.755	0.66
398_A	699_L	0.754	0.66
147_E	150_N	0.753	0.66
95_D	106_I	0.752	0.66
5_R	99_Q	0.752	0.66
563_E	803_L	0.750	0.66
125_I	128_A	0.750	0.66
406_D	413_D	0.749	0.65
709_F	712_T	0.748	0.65
562_M	827_N	0.747	0.65
493_G	503_Y	0.746	0.65
709_F	714_V	0.744	0.65
640_K	688_N	0.744	0.65
144_R	147_E	0.743	0.65
246_V	252_R	0.743	0.65
32_L	36_S	0.743	0.65
465_E	472_T	0.742	0.65
5_R	95_D	0.740	0.65
302_A	551_M	0.740	0.65
493_G	499_S	0.740	0.65
490_R	495_L	0.739	0.64
310_C	401_I	0.739	0.64
456_S	459_E	0.737	0.64
725_I	733_D	0.737	0.64
484_I	487_E	0.735	0.64
451_K	455_Y	0.735	0.64
180_V	398_A	0.734	0.64
403_M	585_R	0.732	0.64
199_K	357_Y	0.732	0.64
517_T	577_V	0.731	0.64
140_I	143_M	0.729	0.63
614_L	763_F	0.727	0.63
435_E	657_E	0.727	0.63
456_S	460_E	0.727	0.63
59_Q	63_D	0.726	0.63
580_V	614_L	0.724	0.63
479_L	486_I	0.724	0.63
14_L	17_A	0.723	0.63
192_Q	399_S	0.723	0.63
25_D	106_I	0.722	0.63
92_N	96_K	0.722	0.63
193_V	399_S	0.722	0.63
66_Q	446_E	0.722	0.63
584_I	713_V	0.722	0.63
32_L	64_I	0.721	0.63
647_V	685_D	0.719	0.62
630_V	674_I	0.719	0.62
490_R	504_G	0.719	0.62
485_A	500_E	0.718	0.62
24_H	65_N	0.717	0.62
193_V	669_R	0.717	0.62
67_A	71_L	0.717	0.62
567_H	764_H	0.716	0.62
69_N	73_Q	0.716	0.62
413_D	417_R	0.716	0.62
674_I	693_V	0.715	0.62
342_S	378_H	0.714	0.62
274_I	833_I	0.712	0.62
165_T	302_A	0.711	0.61
402_R	588_R	0.711	0.61
167_D	557_E	0.711	0.61
768_E	808_Y	0.711	0.61
197_R	778_Q	0.711	0.61
147_E	154_A	0.711	0.61
400_S	542_R	0.708	0.61
486_I	498_M	0.708	0.61
267_A	591_L	0.708	0.61
768_E	804_S	0.707	0.61
245_L	827_N	0.707	0.61
645_R	702_G	0.706	0.61
532_T	630_V	0.705	0.61
737_M	741_V	0.705	0.61
679_V	720_L	0.705	0.61
134_A	140_I	0.705	0.61
479_L	483_K	0.704	0.61
824_Q	828_P	0.704	0.61
699_L	709_F	0.703	0.61
216_V	298_M	0.703	0.61
283_M	302_A	0.702	0.60
475_I	478_E	0.700	0.60
22_L	92_N	0.699	0.60
820_A	828_P	0.699	0.60
776_Q	780_K	0.699	0.60
631_R	691_L	0.699	0.60
68_L	71_L	0.698	0.60
676_L	716_M	0.698	0.60
490_R	499_S	0.698	0.60
735_A	738_K	0.697	0.60
48_P	193_V	0.697	0.60
802_L	824_Q	0.696	0.60
113_L	140_I	0.696	0.60
689_I	702_G	0.696	0.60
483_K	540_L	0.695	0.60
112_V	136_I	0.694	0.60
34_L	90_V	0.693	0.59
378_H	693_V	0.691	0.59
171_R	174_Q	0.689	0.59
465_E	526_L	0.689	0.59
77_T	81_V	0.689	0.59
436_A	440_R	0.688	0.59
799_A	846_L	0.687	0.59
175_G	484_I	0.686	0.59
193_V	280_L	0.685	0.59
487_E	490_R	0.684	0.58
225_N	487_E	0.684	0.58
177_L	777_I	0.684	0.58
406_D	466_K	0.683	0.58
89_R	119_R	0.683	0.58
197_R	398_A	0.683	0.58
475_I	479_L	0.682	0.58
39_L	126_L	0.682	0.58
467_A	470_S	0.681	0.58
49_L	112_V	0.681	0.58
302_A	591_L	0.681	0.58
796_S	848_V	0.680	0.58
757_I	760_V	0.680	0.58
462_W	466_K	0.679	0.58
96_K	100_K	0.679	0.58
517_T	520_E	0.679	0.58
555_E	558_K	0.679	0.58
215_I	714_V	0.679	0.58
47_S	51_T	0.678	0.58
323_I	630_V	0.677	0.58
159_Q	265_D	0.677	0.58
6_L	400_S	0.676	0.58
184_D	222_R	0.676	0.58
149_V	155_E	0.675	0.57
463_K	466_K	0.675	0.57
143_M	146_G	0.675	0.57
775_A	807_G	0.674	0.57
586_R	826_E	0.673	0.57
632_I	674_I	0.673	0.57
625_S	826_E	0.673	0.57
140_I	154_A	0.672	0.57
441_L	445_N	0.672	0.57
526_L	720_L	0.672	0.57
606_P	749_F	0.672	0.57
592_A	826_E	0.670	0.57
734_Y	762_V	0.670	0.57
684_P	830_A	0.670	0.57
504_G	508_E	0.670	0.57
783_Y	792_E	0.669	0.57
133_T	140_I	0.669	0.57
130_G	135_N	0.668	0.57
472_T	476_K	0.667	0.57
187_I	218_G	0.667	0.57
129_A	136_I	0.667	0.57
426_Q	430_M	0.666	0.56
696_D	716_M	0.666	0.56
137_T	141_E	0.666	0.56
29_I	81_V	0.665	0.56
373_A	390_A	0.665	0.56
394_I	539_V	0.665	0.56
216_V	337_F	0.665	0.56
246_V	793_I	0.663	0.56
66_Q	69_N	0.663	0.56
141_E	148_S	0.663	0.56
215_I	338_V	0.662	0.56
462_W	465_E	0.661	0.56
249_A	252_R	0.661	0.56
741_V	812_Y	0.659	0.56
74_V	78_G	0.658	0.56
91_L	111_F	0.658	0.56
200_N	650_P	0.658	0.56
649_A	702_G	0.657	0.55
424_L	428_A	0.657	0.55
381_I	634_M	0.657	0.55
740_L	743_G	0.657	0.55
567_H	571_I	0.657	0.55
602_L	716_M	0.657	0.55
351_R	425_E	0.656	0.55
216_V	221_Q	0.656	0.55
468_S	471_G	0.655	0.55
541_A	551_M	0.655	0.55
434_D	440_R	0.655	0.55
534_A	540_L	0.653	0.55
119_R	123_A	0.653	0.55
59_Q	62_T	0.652	0.55
555_E	588_R	0.651	0.55
399_S	539_V	0.651	0.55
357_Y	392_D	0.650	0.55
693_V	709_F	0.650	0.55
693_V	712_T	0.649	0.55
311_V	674_I	0.648	0.54
728_R	733_D	0.648	0.54
238_L	771_I	0.647	0.54
727_E	736_H	0.646	0.54
632_I	689_I	0.645	0.54
172_A	226_G	0.645	0.54
259_L	299_L	0.645	0.54
739_E	746_S	0.644	0.54
28_F	81_V	0.643	0.54
578_D	581_S	0.643	0.54
113_L	133_T	0.642	0.54
208_P	330_E	0.641	0.54
498_M	830_A	0.640	0.53
803_L	824_Q	0.639	0.53
593_D	753_F	0.638	0.53
343_V	346_T	0.638	0.53
689_I	699_L	0.638	0.53
37_A	41_Q	0.638	0.53
240_L	245_L	0.637	0.53
371_V	440_R	0.637	0.53
565_E	620_N	0.636	0.53
38_L	111_F	0.636	0.53
381_I	389_K	0.636	0.53
640_K	645_R	0.636	0.53
192_Q	401_I	0.635	0.53
684_P	693_V	0.635	0.53
51_T	56_N	0.635	0.53
360_H	403_M	0.634	0.53
14_L	87_L	0.634	0.53
146_G	154_A	0.634	0.53
780_K	795_I	0.634	0.53
63_D	674_I	0.633	0.53
19_S	22_L	0.633	0.53
357_Y	628_A	0.633	0.53
563_E	567_H	0.632	0.53
793_I	846_L	0.632	0.53
422_L	447_E	0.631	0.52
9_K	154_A	0.630	0.52
95_D	642_S	0.630	0.52
759_E	822_Q	0.630	0.52
165_T	169_T	0.629	0.52
632_I	645_R	0.629	0.52
290_D	309_H	0.628	0.52
726_Q	811_V	0.628	0.52
654_V	702_G	0.628	0.52
7_T	103_D	0.628	0.52
791_Y	839_V	0.628	0.52
249_A	259_L	0.628	0.52
585_R	803_L	0.627	0.52
470_S	473_Q	0.627	0.52
408_K	412_L	0.627	0.52
111_F	115_A	0.627	0.52
259_L	295_A	0.626	0.52
568_H	620_N	0.626	0.52
190_T	338_V	0.626	0.52
505_K	509_L	0.626	0.52
56_N	481_Q	0.626	0.52
266_L	275_L	0.624	0.52
373_A	394_I	0.623	0.52
708_D	712_T	0.623	0.52
255_F	295_A	0.623	0.52
97_L	113_L	0.622	0.51
246_V	293_M	0.621	0.51
239_A	536_I	0.619	0.51
427_Q	445_N	0.619	0.51
145_G	148_S	0.618	0.51
249_A	266_L	0.618	0.51
574_N	770_H	0.618	0.51
413_D	637_F	0.618	0.51
323_I	362_H	0.617	0.51
699_L	828_P	0.617	0.51
429_L	533_D	0.617	0.51
688_N	700_T	0.616	0.51
733_D	737_M	0.616	0.51
647_V	674_I	0.616	0.51
579_A	759_E	0.616	0.51
158_R	162_K	0.616	0.51
251_Y	399_S	0.613	0.50
405_I	527_L	0.612	0.50
40_N	65_N	0.612	0.50
645_R	688_N	0.611	0.50
144_R	148_S	0.611	0.50
642_S	702_G	0.609	0.50
50_L	131_A	0.609	0.50
435_E	438_K	0.609	0.50
418_R	476_K	0.609	0.50
340_E	708_D	0.608	0.50
173_E	225_N	0.608	0.50
784_K	788_E	0.608	0.50
744_V	748_N	0.608	0.50
405_I	476_K	0.607	0.50
251_Y	289_A	0.607	0.50
228_V	761_V	0.606	0.50
809_D	816_P	0.606	0.50
539_V	830_A	0.606	0.50
35_M	125_I	0.606	0.50
659_G	749_F	0.606	0.50
453_R	467_A	0.605	0.49
298_M	310_C	0.604	0.49
536_I	811_V	0.604	0.49
465_E	469_L	0.603	0.49
255_F	287_G	0.603	0.49
641_H	720_L	0.603	0.49
165_T	261_G	0.603	0.49
359_L	469_L	0.603	0.49
102_G	110_L	0.602	0.49
47_S	57_A	0.602	0.49
335_K	543_W	0.602	0.49
155_E	158_R	0.601	0.49
226_G	234_G	0.601	0.49
98_A	101_R	0.601	0.49
43_G	48_P	0.600	0.49
579_A	591_L	0.598	0.49
23_G	92_N	0.598	0.49
700_T	706_T	0.597	0.49
92_N	95_D	0.596	0.48
370_I	374_A	0.595	0.48
643_V	666_V	0.595	0.48
828_P	832_Q	0.595	0.48
266_L	269_Q	0.593	0.48
140_I	149_V	0.593	0.48
57_A	60_L	0.593	0.48
138_Q	141_E	0.593	0.48
584_I	747_H	0.592	0.48
696_D	706_T	0.592	0.48
122_L	125_I	0.592	0.48
173_E	519_L	0.591	0.48
35_M	115_A	0.591	0.48
353_L	480_E	0.591	0.48
288_K	317_D	0.591	0.48
60_L	129_A	0.590	0.48
41_Q	47_S	0.590	0.48
489_A	494_D	0.590	0.48
367_D	371_V	0.589	0.48
25_D	73_Q	0.589	0.48
317_D	320_R	0.588	0.48
606_P	718_S	0.588	0.48
447_E	450_D	0.587	0.47
288_K	296_G	0.587	0.47
521_G	525_R	0.587	0.47
197_R	426_Q	0.586	0.47
506_I	628_A	0.586	0.47
777_I	817_L	0.586	0.47
474_T	512_Q	0.586	0.47
46_V	53_A	0.586	0.47
358_E	431_K	0.585	0.47
803_L	843_V	0.585	0.47
199_K	645_R	0.585	0.47
400_S	538_E	0.584	0.47
725_I	762_V	0.584	0.47
429_L	440_R	0.584	0.47
512_Q	515_A	0.583	0.47
197_R	491_R	0.582	0.47
471_G	511_K	0.582	0.47
732_L	736_H	0.582	0.47
598_I	761_V	0.582	0.47
783_Y	794_H	0.582	0.47
58_G	61_R	0.582	0.47
284_V	312_G	0.581	0.47
525_R	532_T	0.580	0.47
279_E	318_E	0.580	0.47
222_R	413_D	0.579	0.47
439_K	784_K	0.578	0.46
587_S	598_I	0.577	0.46
259_L	262_V	0.576	0.46
283_M	577_V	0.575	0.46
641_H	748_N	0.574	0.46
640_K	689_I	0.574	0.46
714_V	725_I	0.574	0.46
22_L	80_D	0.574	0.46
246_V	323_I	0.574	0.46
53_A	136_I	0.574	0.46
485_A	505_K	0.574	0.46
647_V	699_L	0.574	0.46
693_V	748_N	0.574	0.46
695_D	753_F	0.573	0.46
349_I	374_A	0.573	0.46
7_T	105_F	0.572	0.46
567_H	581_S	0.571	0.46
439_K	788_E	0.570	0.45
585_R	621_F	0.570	0.45
582_N	585_R	0.569	0.45
90_V	122_L	0.569	0.45
595_N	781_R	0.569	0.45
566_L	581_S	0.569	0.45
157_Q	244_A	0.569	0.45
90_V	111_F	0.567	0.45
647_V	700_T	0.567	0.45
316_L	337_F	0.567	0.45
34_L	111_F	0.567	0.45
684_P	750_R	0.567	0.45
246_V	254_E	0.566	0.45
317_D	327_A	0.566	0.45
447_E	451_K	0.566	0.45
737_M	762_V	0.566	0.45
509_L	513_L	0.566	0.45
649_A	658_E	0.566	0.45
339_A	342_S	0.566	0.45
208_P	632_I	0.566	0.45
45_S	108_S	0.565	0.45
676_L	710_R	0.565	0.45
165_T	266_L	0.564	0.45
245_L	298_M	0.564	0.45
667_R	705_R	0.563	0.45
28_F	71_L	0.563	0.45
676_L	689_I	0.563	0.45
268_K	511_K	0.563	0.45
672_S	771_I	0.563	0.45
15_A	551_M	0.563	0.45
418_R	451_K	0.562	0.45
429_L	437_S	0.562	0.45
94_C	114_A	0.561	0.44
48_P	51_T	0.561	0.44
385_Q	389_K	0.561	0.44
761_V	823_Q	0.561	0.44
729_F	732_L	0.561	0.44
642_S	754_I	0.561	0.44
378_H	536_I	0.560	0.44
816_P	819_R	0.559	0.44
251_Y	257_E	0.559	0.44
476_K	535_E	0.559	0.44
123_A	133_T	0.559	0.44
58_G	62_T	0.559	0.44
216_V	338_V	0.558	0.44
342_S	436_A	0.558	0.44
638_M	826_E	0.557	0.44
621_F	777_I	0.557	0.44
392_D	645_R	0.557	0.44
157_Q	257_E	0.557	0.44
431_K	500_E	0.557	0.44
131_A	147_E	0.557	0.44
562_M	715_I	0.556	0.44
496_A	504_G	0.555	0.44
433_S	437_S	0.555	0.44
466_K	470_S	0.555	0.44
631_R	816_P	0.554	0.44
285_G	297_N	0.554	0.44
340_E	378_H	0.554	0.44
199_K	688_N	0.553	0.44
347_I	375_T	0.553	0.44
640_K	700_T	0.553	0.44
259_L	285_G	0.552	0.43
123_A	126_L	0.552	0.43
439_K	796_S	0.552	0.43
676_L	808_Y	0.552	0.43
45_S	48_P	0.552	0.43
112_V	131_A	0.551	0.43
796_S	825_I	0.551	0.43
446_E	457_E	0.551	0.43
410_E	538_E	0.550	0.43
493_G	501_L	0.550	0.43
621_F	628_A	0.550	0.43
499_S	562_M	0.550	0.43
509_L	518_Q	0.550	0.43
58_G	454_Q	0.549	0.43
445_N	449_S	0.549	0.43
140_I	716_M	0.549	0.43
630_V	640_K	0.549	0.43
129_A	132_T	0.549	0.43
375_T	788_E	0.548	0.43
56_N	657_E	0.548	0.43
532_T	625_S	0.548	0.43
810_P	816_P	0.548	0.43
633_D	816_P	0.547	0.43
56_N	674_I	0.547	0.43
791_Y	846_L	0.547	0.43
121_T	125_I	0.547	0.43
222_R	539_V	0.547	0.43
802_L	805_E	0.546	0.43
280_L	335_K	0.545	0.43
244_A	793_I	0.545	0.43
508_E	513_L	0.545	0.43
781_R	784_K	0.545	0.43
197_R	356_R	0.544	0.43
165_T	283_M	0.544	0.43
25_D	761_V	0.544	0.43
217_E	305_R	0.544	0.43
486_I	503_Y	0.543	0.42
106_I	674_I	0.543	0.42
207_E	411_E	0.542	0.42
274_I	552_M	0.542	0.42
570_V	718_S	0.542	0.42
498_M	503_Y	0.542	0.42
468_S	782_L	0.541	0.42
791_Y	842_K	0.541	0.42
797_D	800_L	0.541	0.42
616_K	696_D	0.541	0.42
82_Q	85_Q	0.541	0.42
177_L	283_M	0.541	0.42
415_L	419_I	0.541	0.42
721_G	738_K	0.540	0.42
64_I	67_A	0.539	0.42
734_Y	738_K	0.539	0.42
29_I	87_L	0.538	0.42
158_R	265_D	0.538	0.42
241_D	244_A	0.538	0.42
92_N	99_Q	0.537	0.42
88_V	92_N	0.537	0.42
401_I	535_E	0.536	0.42
689_I	753_F	0.536	0.42
366_T	533_D	0.536	0.42
803_L	821_I	0.536	0.42
45_S	158_R	0.535	0.42
208_P	391_I	0.535	0.42
588_R	713_V	0.535	0.42
386_L	390_A	0.535	0.42
453_R	460_E	0.535	0.42
722_S	725_I	0.534	0.41
473_Q	476_K	0.534	0.41
472_T	516_A	0.534	0.41
425_E	428_A	0.533	0.41
156_D	246_V	0.533	0.41
794_H	797_D	0.533	0.41
353_L	703_Q	0.533	0.41
35_M	564_Q	0.533	0.41
15_A	18_Q	0.533	0.41
443_M	447_E	0.533	0.41
818_K	827_N	0.533	0.41
283_M	292_A	0.533	0.41
163_K	249_A	0.532	0.41
465_E	476_K	0.531	0.41
172_A	777_I	0.531	0.41
103_D	110_L	0.530	0.41
472_T	519_L	0.530	0.41
227_E	668_R	0.529	0.41
642_S	685_D	0.528	0.41
347_I	584_I	0.528	0.41
650_P	653_Y	0.528	0.41
74_V	77_T	0.528	0.41
553_E	557_E	0.527	0.41
674_I	713_V	0.526	0.41
479_L	507_P	0.526	0.41
586_R	827_N	0.526	0.41
598_I	623_F	0.525	0.40
199_K	700_T	0.525	0.40
429_L	448_L	0.525	0.40
13_A	44_G	0.525	0.40
23_G	65_N	0.524	0.40
799_A	847_E	0.524	0.40
638_M	689_I	0.524	0.40
663_T	707_V	0.524	0.40
163_K	236_R	0.524	0.40
770_H	773_S	0.524	0.40
145_G	159_Q	0.523	0.40
666_V	672_S	0.523	0.40
539_V	620_N	0.523	0.40
491_R	503_Y	0.523	0.40
107_S	145_G	0.522	0.40
754_I	760_V	0.522	0.40
6_L	14_L	0.522	0.40
275_L	308_L	0.521	0.40
489_A	501_L	0.521	0.40
511_K	837_E	0.521	0.40
638_M	643_V	0.521	0.40
349_I	647_V	0.521	0.40
146_G	266_L	0.520	0.40
534_A	777_I	0.520	0.40
273_V	845_R	0.520	0.40
461_E	526_L	0.520	0.40
412_L	459_E	0.518	0.40
585_R	628_A	0.518	0.40
103_D	109_E	0.518	0.40
454_Q	767_G	0.517	0.40
68_L	149_V	0.517	0.40
583_A	598_I	0.516	0.39
656_Y	702_G	0.515	0.39
10_F	14_L	0.515	0.39
19_S	23_G	0.514	0.39
45_S	676_L	0.514	0.39
585_R	820_A	0.514	0.39
494_D	504_G	0.514	0.39
788_E	830_A	0.514	0.39
287_G	318_E	0.513	0.39
552_M	829_L	0.513	0.39
118_S	128_A	0.513	0.39
62_T	735_A	0.513	0.39
536_I	851_D	0.512	0.39
16_D	40_N	0.512	0.39
90_V	118_S	0.512	0.39
738_K	741_V	0.512	0.39
550_R	555_E	0.512	0.39
791_Y	840_P	0.512	0.39
429_L	441_L	0.512	0.39
582_N	823_Q	0.511	0.39
86_D	128_A	0.511	0.39
298_M	834_L	0.511	0.39
440_R	444_L	0.511	0.39
629_M	674_I	0.511	0.39
502_Q	506_I	0.511	0.39
243_G	354_K	0.510	0.39
691_L	700_T	0.510	0.39
613_E	617_A	0.510	0.39
461_E	525_R	0.510	0.39
287_G	297_N	0.510	0.39
591_L	826_E	0.509	0.39
729_F	737_M	0.509	0.39
154_A	158_R	0.509	0.39
609_V	638_M	0.509	0.39
481_Q	484_I	0.509	0.39
243_G	275_L	0.509	0.39
400_S	403_M	0.509	0.39
786_L	795_I	0.509	0.39
237_V	604_L	0.508	0.39
587_S	596_R	0.508	0.39
316_L	705_R	0.508	0.39
553_E	830_A	0.507	0.38
347_I	847_E	0.507	0.38
399_S	589_A	0.506	0.38
582_N	629_M	0.506	0.38
126_L	131_A	0.505	0.38
52_S	133_T	0.504	0.38
560_L	835_S	0.504	0.38
195_Q	231_G	0.504	0.38
109_E	140_I	0.504	0.38
769_Q	772_A	0.503	0.38
593_D	818_K	0.503	0.38
392_D	688_N	0.503	0.38
808_Y	816_P	0.503	0.38
91_L	779_L	0.502	0.38
137_T	147_E	0.502	0.38
192_Q	778_Q	0.501	0.38
35_M	613_E	0.501	0.38
208_P	623_F	0.501	0.38
167_D	708_D	0.500	0.38
606_P	720_L	0.500	0.38
225_N	442_D	0.500	0.38
512_Q	516_A	0.500	0.38

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1qvrA	3	0.9335	100	0.438	Contact Map
4d2uA	3	0.9195	100	0.439	Contact Map
1r6bX	1	0.8075	100	0.484	Contact Map
3pxiA	3	0.8308	100	0.506	Contact Map
4ciuA	1	0.7655	100	0.572	Contact Map
3pxgA	3	0.5146	100	0.735	Contact Map
3vkgA	2	0.7993	100	0.771	Contact Map
4hseA	1	0.4306	100	0.775	Contact Map
4lj9A	1	0.3851	100	0.824	Contact Map
4akgA	2	0.7993	100	0.831	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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