GADC - ECOLI - GREMLIN Contacts

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GADC - Probable glutamate/gamma-aminobutyrate antiporter

UniProt:	P63235	Sequences: MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVFFLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIGFIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGFFAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVFVAFILSYMGVEASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFTVLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNKNGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVLVLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLVVSFLVVLALPFILYAVHDRKGKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMNDKKH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12456
Length:	511 (426)
Sequences:	24628 (16173)
Seq/√Len:	783.6

ECOLI - GADC YGJI YCAM ANSP AROP YJEM GABP LYSP YIFK MMUP PUUP PROY PHEP POTE ADIC CYCA PLAP FRLA YBAT ARCD CADB YJEH
BACSU - ASPP ROCC YBEC YBGF YTNA HUTM GABP YBXG AAPA YDGF ROCE STET YHDG YVBW ARCD YCGH YFNA YECA YDAO GERBB GERAB YNDE
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97WS3 Q97X49 Q97XM0 Q97Z63 Q97U05 Q7LXI7 Q97VA8 Q97ZB5 Q97VA6 Q97WD4 Q97U33 Q97VR4 Q97Y76 Q97U39 Q97YX9 Q97YN3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
142_A	346_L	4.356	1.00
328_A	340_T	4.288	1.00
391_V	395_K	3.464	1.00
50_G	246_I	3.166	1.00
331_K	340_T	3.145	1.00
232_R	236_L	2.962	1.00
14_T	228_S	2.911	1.00
76_F	322_K	2.867	1.00
383_F	420_L	2.747	1.00
227_M	233_D	2.730	1.00
92_I	319_T	2.681	1.00
229_N	232_R	2.678	1.00
320_A	330_A	2.617	1.00
333_N	339_V	2.539	1.00
19_F	240_L	2.495	1.00
63_E	393_V	2.492	1.00
175_A	255_S	2.486	1.00
135_L	350_S	2.479	1.00
225_N	321_Q	2.476	1.00
15_L	240_L	2.412	1.00
328_A	331_K	2.411	1.00
288_W	292_V	2.358	1.00
30_Y	33_P	2.331	1.00
15_L	233_D	2.195	1.00
80_S	88_G	2.191	1.00
343_I	347_V	2.185	1.00
317_Y	321_Q	2.161	1.00
226_E	314_R	2.161	1.00
15_L	19_F	2.157	1.00
142_A	342_V	2.123	1.00
143_L	147_G	2.116	1.00
150_K	154_R	2.089	1.00
18_F	227_M	2.088	1.00
173_A	177_I	2.077	1.00
139_W	350_S	2.054	1.00
146_F	339_V	1.992	1.00
83_L	391_V	1.982	1.00
96_Y	345_Q	1.962	1.00
277_V	280_S	1.959	1.00
14_T	17_G	1.956	1.00
323_N	327_A	1.950	1.00
80_S	85_P	1.928	1.00
417_I	421_L	1.920	1.00
135_L	353_L	1.919	1.00
134_A	353_L	1.902	1.00
458_A	462_I	1.898	1.00
60_C	386_F	1.894	1.00
236_L	240_L	1.878	1.00
51_I	55_I	1.864	1.00
161_F	165_L	1.850	1.00
329_F	344_S	1.849	1.00
261_P	264_E	1.848	1.00
333_N	337_V	1.841	1.00
34_T	38_S	1.831	1.00
9_K	332_M	1.812	1.00
239_L	243_V	1.810	1.00
459_L	463_L	1.803	1.00
452_S	456_V	1.789	1.00
83_L	387_I	1.768	1.00
29_V	32_Y	1.763	1.00
17_G	157_K	1.759	1.00
22_T	241_L	1.742	1.00
29_V	33_P	1.738	1.00
79_V	91_A	1.736	1.00
91_A	384_M	1.721	1.00
264_E	281_H	1.714	1.00
412_K	416_A	1.702	1.00
454_L	458_A	1.690	1.00
145_Q	306_A	1.689	1.00
84_G	87_W	1.689	1.00
386_F	419_G	1.683	1.00
413_L	417_I	1.681	1.00
421_L	425_M	1.677	1.00
229_N	233_D	1.658	1.00
139_W	346_L	1.649	1.00
129_T	132_I	1.646	1.00
448_L	452_S	1.627	1.00
19_F	244_A	1.626	1.00
146_F	343_I	1.625	1.00
107_L	305_I	1.618	1.00
138_L	349_T	1.608	1.00
13_L	17_G	1.602	1.00
45_F	206_V	1.600	1.00
452_S	455_V	1.592	1.00
277_V	281_H	1.591	1.00
103_F	349_T	1.576	1.00
193_T	196_P	1.574	1.00
243_V	247_C	1.571	1.00
457_L	460_P	1.568	1.00
335_N	339_V	1.558	1.00
114_L	133_A	1.549	1.00
431_F	434_P	1.542	1.00
34_T	42_L	1.539	1.00
229_N	236_L	1.532	1.00
166_L	296_L	1.519	1.00
391_V	394_L	1.507	1.00
450_V	454_L	1.497	1.00
187_I	191_S	1.495	1.00
453_F	457_L	1.456	1.00
223_H	310_V	1.450	1.00
316_M	341_L	1.444	1.00
165_L	170_I	1.442	1.00
445_Y	452_S	1.437	1.00
49_G	210_F	1.424	1.00
340_T	344_S	1.418	1.00
327_A	331_K	1.413	1.00
147_G	335_N	1.408	1.00
456_V	460_P	1.402	1.00
107_L	138_L	1.400	1.00
138_L	346_L	1.400	1.00
387_I	391_V	1.398	1.00
313_S	342_V	1.387	1.00
17_G	153_A	1.387	1.00
83_L	87_W	1.381	1.00
317_Y	332_M	1.369	1.00
194_F	197_D	1.363	1.00
444_M	447_E	1.362	1.00
291_R	295_A	1.359	1.00
312_P	345_Q	1.359	1.00
72_E	225_N	1.350	1.00
128_I	132_I	1.348	1.00
58_G	242_M	1.343	1.00
142_A	343_I	1.342	1.00
423_S	426_A	1.337	1.00
280_S	290_V	1.336	1.00
414_V	418_V	1.331	1.00
110_V	137_I	1.327	1.00
195_F	198_F	1.323	1.00
10_A	336_G	1.318	1.00
327_A	330_A	1.318	1.00
57_V	386_F	1.312	1.00
187_I	190_D	1.311	1.00
110_V	298_L	1.310	1.00
135_L	139_W	1.303	1.00
79_V	384_M	1.303	1.00
82_T	388_G	1.302	1.00
230_P	235_P	1.293	1.00
316_M	325_L	1.277	1.00
15_L	236_L	1.274	1.00
86_R	461_F	1.266	1.00
13_L	153_A	1.265	1.00
164_I	169_F	1.259	1.00
247_C	251_V	1.259	1.00
331_K	339_V	1.259	1.00
68_D	81_N	1.258	1.00
431_F	435_D	1.254	1.00
460_P	464_Y	1.252	1.00
177_I	182_G	1.235	1.00
43_V	254_L	1.231	1.00
387_I	420_L	1.225	1.00
59_L	239_L	1.217	1.00
106_M	304_E	1.217	1.00
13_L	18_F	1.214	1.00
9_K	317_Y	1.213	1.00
58_G	238_M	1.200	1.00
396_H	399_L	1.196	1.00
71_E	77_A	1.196	1.00
426_A	430_S	1.194	1.00
141_L	305_I	1.193	1.00
41_S	195_F	1.189	1.00
26_V	245_A	1.183	1.00
52_L	422_T	1.180	1.00
77_A	81_N	1.178	1.00
22_T	220_S	1.178	1.00
126_D	129_T	1.172	1.00
414_V	417_I	1.168	1.00
233_D	236_L	1.161	1.00
67_V	401_R	1.158	1.00
425_M	429_V	1.153	1.00
131_T	135_L	1.153	1.00
144_T	155_I	1.151	1.00
194_F	198_F	1.150	1.00
193_T	197_D	1.149	1.00
16_L	20_A	1.148	1.00
286_I	289_T	1.147	1.00
445_Y	448_L	1.147	1.00
457_L	461_F	1.143	1.00
18_F	237_A	1.141	1.00
428_I	432_L	1.137	1.00
419_G	423_S	1.135	1.00
79_V	87_W	1.125	1.00
204_L	425_M	1.125	1.00
71_E	81_N	1.121	1.00
262_G	265_I	1.121	1.00
407_G	413_L	1.118	1.00
170_I	174_L	1.117	1.00
340_T	343_I	1.113	1.00
176_A	180_H	1.113	1.00
61_A	75_V	1.110	1.00
23_A	244_A	1.103	1.00
424_I	428_I	1.101	1.00
156_A	306_A	1.092	1.00
280_S	287_E	1.090	1.00
171_L	175_A	1.083	1.00
12_Q	228_S	1.081	1.00
142_A	146_F	1.079	1.00
65_A	78_W	1.078	1.00
89_F	93_S	1.076	1.00
155_I	159_G	1.074	1.00
455_V	459_L	1.074	1.00
176_A	255_S	1.073	1.00
443_D	447_E	1.066	1.00
169_F	173_A	1.062	1.00
81_N	396_H	1.054	1.00
397_P	401_R	1.053	1.00
456_V	462_I	1.053	1.00
132_I	136_I	1.051	1.00
180_H	184_P	1.048	1.00
179_L	258_M	1.047	1.00
413_L	430_S	1.047	1.00
273_Q	277_V	1.046	1.00
451_V	455_V	1.042	1.00
321_Q	330_A	1.037	1.00
76_F	318_V	1.036	1.00
136_I	140_A	1.034	1.00
96_Y	316_M	1.034	1.00
114_L	118_L	1.031	1.00
67_V	399_L	1.031	1.00
419_G	422_T	1.030	1.00
228_S	233_D	1.029	1.00
456_V	463_L	1.029	1.00
111_L	133_A	1.022	1.00
55_I	418_V	1.022	1.00
416_A	420_L	1.019	1.00
403_F	406_P	1.018	1.00
146_F	337_V	1.017	1.00
458_A	461_F	1.015	1.00
423_S	427_F	1.014	1.00
261_P	281_H	1.011	1.00
446_V	450_V	1.008	1.00
172_I	251_V	1.008	1.00
445_Y	456_V	1.003	1.00
50_G	214_Y	1.002	1.00
332_M	336_G	0.997	1.00
447_E	451_V	0.996	1.00
41_S	203_T	0.996	1.00
398_D	401_R	0.996	1.00
182_G	185_V	0.995	1.00
21_I	223_H	0.994	1.00
427_F	430_S	0.994	1.00
420_L	424_I	0.994	1.00
459_L	462_I	0.991	1.00
347_V	351_I	0.989	1.00
149_T	310_V	0.985	1.00
114_L	298_L	0.984	1.00
215_M	378_Y	0.970	1.00
154_R	158_V	0.967	1.00
181_S	184_P	0.967	1.00
146_F	333_N	0.963	1.00
139_W	143_L	0.962	1.00
416_A	430_S	0.956	1.00
180_H	183_A	0.952	1.00
27_M	163_G	0.952	1.00
159_G	303_A	0.950	1.00
38_S	41_S	0.949	1.00
403_F	407_G	0.949	1.00
427_F	431_F	0.943	1.00
47_L	250_S	0.942	1.00
422_T	426_A	0.939	1.00
426_A	429_V	0.934	1.00
218_E	222_T	0.930	1.00
111_L	134_A	0.930	1.00
397_P	400_K	0.929	1.00
35_F	42_L	0.928	1.00
105_P	212_L	0.927	1.00
164_I	248_L	0.926	1.00
175_A	259_V	0.923	1.00
63_E	66_T	0.917	1.00
461_F	465_A	0.911	1.00
224_V	234_Y	0.907	1.00
12_Q	150_K	0.900	1.00
383_F	387_I	0.899	1.00
47_L	51_I	0.898	1.00
456_V	459_L	0.898	1.00
333_N	336_G	0.894	1.00
163_G	300_G	0.892	1.00
20_A	157_K	0.890	1.00
84_G	462_I	0.884	1.00
51_I	414_V	0.882	1.00
66_T	402_T	0.874	1.00
449_L	452_S	0.873	1.00
43_V	257_A	0.872	1.00
177_I	181_S	0.871	1.00
394_L	397_P	0.871	1.00
339_V	343_I	0.868	1.00
16_L	157_K	0.863	1.00
454_L	457_L	0.862	1.00
179_L	183_A	0.861	1.00
141_L	306_A	0.860	1.00
285_E	289_T	0.854	1.00
399_L	402_T	0.854	1.00
309_I	346_L	0.854	1.00
17_G	154_R	0.854	1.00
274_T	279_M	0.854	1.00
417_I	420_L	0.853	1.00
79_V	388_G	0.851	1.00
416_A	423_S	0.849	1.00
193_T	198_F	0.843	1.00
445_Y	454_L	0.841	1.00
329_F	340_T	0.839	1.00
425_M	428_I	0.835	1.00
358_N	367_F	0.834	1.00
105_P	371_L	0.833	1.00
9_K	226_E	0.833	1.00
111_L	130_K	0.828	1.00
240_L	244_A	0.828	1.00
42_L	253_G	0.827	1.00
23_A	245_A	0.826	1.00
80_S	322_K	0.825	1.00
346_L	350_S	0.824	1.00
9_K	314_R	0.824	1.00
140_A	302_L	0.823	1.00
179_L	184_P	0.821	1.00
420_L	423_S	0.821	1.00
279_M	282_V	0.819	1.00
426_A	431_F	0.814	1.00
60_C	416_A	0.812	1.00
287_E	291_R	0.811	1.00
195_F	199_S	0.810	1.00
325_L	329_F	0.806	1.00
444_M	448_L	0.805	1.00
442_T	445_Y	0.805	1.00
44_F	47_L	0.804	1.00
182_G	186_A	0.802	1.00
449_L	453_F	0.802	1.00
171_L	279_M	0.800	1.00
456_V	461_F	0.800	1.00
415_V	419_G	0.798	1.00
172_I	255_S	0.797	1.00
430_S	434_P	0.796	1.00
73_G	76_F	0.795	1.00
87_W	384_M	0.793	1.00
215_M	382_Y	0.793	1.00
460_P	463_L	0.792	1.00
54_F	59_L	0.789	1.00
430_S	433_P	0.788	1.00
86_R	90_A	0.785	1.00
235_P	238_M	0.784	1.00
93_S	325_L	0.782	1.00
110_V	302_L	0.781	1.00
143_L	146_F	0.779	1.00
428_I	431_F	0.777	1.00
416_A	419_G	0.776	1.00
34_T	39_G	0.774	1.00
413_L	416_A	0.773	1.00
254_L	258_M	0.771	1.00
115_S	130_K	0.770	1.00
133_A	136_I	0.769	1.00
422_T	425_M	0.768	1.00
28_A	249_S	0.768	1.00
55_I	415_V	0.767	1.00
110_V	301_V	0.767	1.00
219_A	311_G	0.765	1.00
448_L	451_V	0.764	1.00
373_L	377_I	0.763	1.00
42_L	45_F	0.761	1.00
246_I	250_S	0.759	1.00
383_F	423_S	0.759	1.00
416_A	426_A	0.754	1.00
195_F	203_T	0.753	1.00
35_F	38_S	0.752	1.00
64_M	78_W	0.751	1.00
268_S	277_V	0.748	1.00
138_L	353_L	0.747	1.00
73_G	77_A	0.746	1.00
396_H	401_R	0.744	1.00
450_V	457_L	0.743	1.00
179_L	182_G	0.743	1.00
172_I	176_A	0.743	1.00
183_A	186_A	0.742	1.00
259_V	278_L	0.738	1.00
131_T	353_L	0.738	1.00
459_L	464_Y	0.737	1.00
146_F	335_N	0.737	1.00
447_E	450_V	0.737	1.00
15_L	237_A	0.736	1.00
95_G	99_I	0.735	1.00
328_A	344_S	0.734	1.00
462_I	465_A	0.731	1.00
54_F	239_L	0.730	1.00
141_L	309_I	0.729	1.00
44_F	203_T	0.726	1.00
347_V	350_S	0.725	1.00
443_D	446_V	0.724	1.00
43_V	47_L	0.724	1.00
154_R	157_K	0.723	1.00
64_M	389_Y	0.723	1.00
19_F	237_A	0.722	1.00
44_F	48_L	0.721	1.00
108_Y	370_A	0.720	1.00
404_N	407_G	0.719	1.00
67_V	402_T	0.719	1.00
114_L	137_I	0.717	1.00
43_V	46_L	0.717	1.00
229_N	235_P	0.715	1.00
147_G	151_Y	0.715	1.00
205_V	209_A	0.713	1.00
76_F	80_S	0.711	1.00
46_L	49_G	0.704	1.00
456_V	464_Y	0.703	1.00
240_L	243_V	0.702	1.00
102_G	374_T	0.699	1.00
316_M	344_S	0.696	1.00
192_K	197_D	0.696	1.00
25_M	307_S	0.695	1.00
338_P	341_L	0.693	1.00
82_T	391_V	0.692	1.00
448_L	453_F	0.691	1.00
186_A	193_T	0.689	1.00
450_V	461_F	0.689	1.00
61_A	385_L	0.684	1.00
448_L	454_L	0.683	1.00
100_A	348_I	0.680	1.00
199_S	203_T	0.679	1.00
451_V	454_L	0.678	1.00
98_Q	378_Y	0.677	1.00
446_V	452_S	0.676	1.00
145_Q	310_V	0.676	1.00
175_A	179_L	0.675	1.00
40_F	257_A	0.674	1.00
177_I	180_H	0.674	1.00
145_Q	342_V	0.673	1.00
275_F	279_M	0.673	1.00
175_A	180_H	0.673	1.00
390_I	416_A	0.672	1.00
423_S	430_S	0.671	1.00
187_I	192_K	0.669	1.00
25_M	28_A	0.669	1.00
309_I	313_S	0.667	1.00
72_E	317_Y	0.666	1.00
181_S	185_V	0.666	1.00
393_V	397_P	0.666	1.00
288_W	291_R	0.665	1.00
442_T	448_L	0.664	1.00
55_I	60_C	0.664	1.00
16_L	154_R	0.663	1.00
386_F	420_L	0.661	1.00
446_V	456_V	0.660	1.00
67_V	70_W	0.660	1.00
390_I	417_I	0.659	1.00
221_A	238_M	0.653	1.00
432_L	435_D	0.650	1.00
390_I	394_L	0.650	1.00
178_Y	181_S	0.649	1.00
12_Q	149_T	0.648	1.00
192_K	195_F	0.648	1.00
453_F	456_V	0.647	1.00
127_P	130_K	0.647	1.00
376_V	427_F	0.645	1.00
101_I	373_L	0.644	1.00
448_L	455_V	0.641	1.00
162_A	166_L	0.641	1.00
416_A	427_F	0.640	1.00
282_V	285_E	0.639	1.00
58_G	217_V	0.639	1.00
137_I	305_I	0.638	1.00
28_A	163_G	0.638	1.00
314_R	317_Y	0.638	1.00
460_P	465_A	0.635	1.00
153_A	157_K	0.634	1.00
422_T	428_I	0.634	1.00
244_A	247_C	0.634	1.00
23_A	160_F	0.633	1.00
135_L	354_I	0.633	1.00
402_T	406_P	0.633	1.00
329_F	341_L	0.633	1.00
12_Q	16_L	0.632	1.00
225_N	317_Y	0.631	1.00
419_G	426_A	0.628	1.00
334_K	339_V	0.627	1.00
83_L	388_G	0.626	1.00
443_D	448_L	0.623	1.00
453_F	460_P	0.621	1.00
388_G	392_L	0.619	1.00
34_T	40_F	0.619	1.00
251_V	255_S	0.619	1.00
234_Y	238_M	0.619	1.00
94_F	381_A	0.617	1.00
84_G	88_G	0.616	1.00
313_S	341_L	0.615	1.00
179_L	255_S	0.614	1.00
76_F	88_G	0.614	1.00
273_Q	276_T	0.613	1.00
266_N	269_A	0.612	1.00
202_G	205_V	0.612	1.00
389_Y	393_V	0.611	1.00
461_F	464_Y	0.611	1.00
131_T	134_A	0.610	1.00
82_T	392_L	0.610	1.00
99_I	308_W	0.609	1.00
27_M	248_L	0.609	1.00
423_S	435_D	0.608	1.00
449_L	454_L	0.607	1.00
24_S	160_F	0.606	1.00
149_T	223_H	0.605	1.00
19_F	22_T	0.603	1.00
16_L	19_F	0.603	1.00
25_M	219_A	0.603	1.00
146_F	342_V	0.603	1.00
102_G	105_P	0.603	1.00
153_A	306_A	0.602	1.00
444_M	450_V	0.601	1.00
227_M	234_Y	0.601	1.00
113_A	297_L	0.601	1.00
65_A	221_A	0.599	1.00
67_V	397_P	0.599	1.00
442_T	446_V	0.599	1.00
448_L	459_L	0.596	1.00
76_F	92_I	0.596	1.00
192_K	196_P	0.595	1.00
116_Y	294_S	0.595	1.00
178_Y	184_P	0.594	1.00
162_A	296_L	0.593	1.00
445_Y	458_A	0.592	1.00
75_V	218_E	0.587	1.00
320_A	329_F	0.586	1.00
141_L	302_L	0.586	1.00
332_M	335_N	0.586	1.00
215_M	218_E	0.585	1.00
46_L	213_S	0.584	1.00
174_L	286_I	0.583	1.00
104_I	370_A	0.583	1.00
276_T	280_S	0.583	1.00
295_A	299_L	0.582	1.00
443_D	456_V	0.582	1.00
244_A	248_L	0.581	1.00
446_V	455_V	0.580	1.00
455_V	458_A	0.579	1.00
65_A	234_Y	0.578	1.00
269_A	274_T	0.578	1.00
43_V	250_S	0.576	1.00
64_M	82_T	0.576	1.00
176_A	251_V	0.576	1.00
383_F	424_I	0.574	1.00
151_Y	154_R	0.574	1.00
184_P	257_A	0.573	1.00
178_Y	183_A	0.573	1.00
100_A	345_Q	0.573	1.00
256_I	275_F	0.573	1.00
139_W	142_A	0.568	1.00
53_W	217_V	0.568	1.00
430_S	435_D	0.567	1.00
35_F	39_G	0.566	1.00
447_E	454_L	0.561	1.00
106_M	301_V	0.560	1.00
117_I	294_S	0.560	1.00
213_S	249_S	0.559	1.00
48_L	207_F	0.558	1.00
172_I	252_G	0.558	1.00
148_G	151_Y	0.556	1.00
138_L	350_S	0.556	1.00
450_V	453_F	0.555	1.00
119_K	126_D	0.554	1.00
215_M	374_T	0.554	1.00
448_L	460_P	0.553	1.00
75_V	222_T	0.553	1.00
252_G	256_I	0.552	1.00
255_S	258_M	0.552	1.00
407_G	412_K	0.551	1.00
252_G	275_F	0.548	1.00
74_G	221_A	0.548	1.00
279_M	286_I	0.546	1.00
151_Y	155_I	0.546	1.00
222_T	311_G	0.545	1.00
344_S	348_I	0.544	1.00
106_M	305_I	0.542	1.00
18_F	233_D	0.542	1.00
36_A	39_G	0.542	1.00
445_Y	453_F	0.541	1.00
174_L	178_Y	0.540	1.00
104_I	352_A	0.539	1.00
137_I	302_L	0.539	1.00
351_I	354_I	0.539	1.00
25_M	308_W	0.537	1.00
23_A	27_M	0.536	1.00
428_I	433_P	0.536	1.00
139_W	343_I	0.536	1.00
292_V	296_L	0.535	1.00
419_G	430_S	0.534	1.00
111_L	114_L	0.534	1.00
40_F	43_V	0.532	1.00
218_E	382_Y	0.531	1.00
312_P	316_M	0.531	1.00
415_V	422_T	0.531	1.00
231_G	236_L	0.530	1.00
445_Y	450_V	0.530	1.00
117_I	298_L	0.530	1.00
160_F	163_G	0.530	1.00
413_L	433_P	0.529	1.00
421_L	424_I	0.529	1.00
142_A	309_I	0.528	1.00
26_V	241_L	0.528	1.00
49_G	52_L	0.527	1.00
415_V	423_S	0.526	1.00
314_R	338_P	0.526	1.00
300_G	303_A	0.525	1.00
407_G	415_V	0.525	1.00
446_V	461_F	0.525	1.00
416_A	431_F	0.525	1.00
104_I	349_T	0.525	1.00
156_A	303_A	0.522	1.00
34_T	37_T	0.522	1.00
24_S	27_M	0.522	1.00
152_T	310_V	0.521	1.00
454_L	461_F	0.521	1.00
24_S	28_A	0.520	1.00
377_I	381_A	0.520	1.00
113_A	276_T	0.519	1.00
57_V	218_E	0.519	1.00
46_L	253_G	0.519	1.00
63_E	406_P	0.517	1.00
368_L	371_L	0.517	1.00
447_E	456_V	0.516	1.00
62_A	66_T	0.515	1.00
49_G	211_I	0.514	1.00
444_M	455_V	0.514	1.00
93_S	452_S	0.514	1.00
157_K	161_F	0.514	1.00
157_K	160_F	0.513	1.00
57_V	423_S	0.513	1.00
426_A	434_P	0.511	1.00
57_V	419_G	0.510	1.00
230_P	233_D	0.510	1.00
394_L	413_L	0.510	1.00
226_E	338_P	0.509	1.00
444_M	458_A	0.509	1.00
58_G	62_A	0.507	1.00
249_S	253_G	0.507	1.00
102_G	106_M	0.506	1.00
19_F	241_L	0.504	1.00
106_M	109_F	0.504	1.00
192_K	198_F	0.503	1.00
42_L	46_L	0.502	1.00
389_Y	416_A	0.501	1.00
416_A	433_P	0.501	1.00
412_K	427_F	0.501	1.00
419_G	427_F	0.500	1.00
22_T	26_V	0.500	1.00
446_V	451_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4djkA	2	0.8728	100	0.323	Contact Map
3l1lA	2	0.8219	100	0.383	Contact Map
3giaA	1	0.8376	100	0.425	Contact Map
2jlnA	1	0.82	99.1	0.862	Contact Map
4xp4A	1	0.8885	98.4	0.893	Contact Map
3dh4A	3	0.8474	98.3	0.895	Contact Map
2xq2A	2	0.8474	98.3	0.896	Contact Map
2a65A	2	0.863	98.1	0.9	Contact Map
4us3A	1	0.7613	98.1	0.901	Contact Map
4wgvA	2	0.7143	97.6	0.911	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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