RL5 - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

RL5 - 50S ribosomal protein L5

UniProt:	P62399	Sequences: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10868
Length:	179 (176)
Sequences:	2683 (1138)
Seq/√Len:	85.8

ECOLI - RL5
BACSU - RL5
HALSA - RL5
SULSO - RL5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
3_K	101_E	4.661	1.00
6_D	10_D	4.101	1.00
36_L	61_S	3.489	1.00
129_S	155_T	3.166	1.00
19_E	168_A	3.098	1.00
7_Y	11_E	3.038	1.00
13_V	28_V	2.406	1.00
34_I	100_F	2.341	1.00
117_L	175_F	2.323	1.00
35_T	157_T	2.310	1.00
108_V	111_I	2.302	1.00
22_Y	165_E	2.242	1.00
15_K	18_T	2.170	1.00
31_V	156_I	2.170	1.00
168_A	172_A	2.159	1.00
132_V	137_I	2.137	1.00
68_T	88_K	2.121	1.00
58_A	64_K	2.106	1.00
98_E	102_R	1.983	1.00
103_L	130_M	1.957	1.00
100_F	156_I	1.921	1.00
38_M	53_A	1.889	1.00
124_G	163_D	1.882	1.00
11_E	15_K	1.873	1.00
7_Y	12_V	1.872	1.00
5_H	9_K	1.858	1.00
119_A	167_R	1.796	1.00
142_D	145_K	1.795	1.00
9_K	13_V	1.791	1.00
168_A	171_A	1.788	1.00
100_F	104_I	1.773	1.00
97_W	173_F	1.757	1.00
167_R	171_A	1.724	1.00
58_A	65_P	1.699	1.00
69_K	84_P	1.677	1.00
22_Y	162_S	1.674	1.00
17_M	28_V	1.671	1.00
20_F	168_A	1.641	1.00
101_E	105_T	1.640	1.00
57_L	87_C	1.623	1.00
15_K	172_A	1.618	1.00
38_M	57_L	1.603	1.00
12_V	173_F	1.587	1.00
70_A	73_S	1.570	1.00
27_Q	161_K	1.537	1.00
40_V	53_A	1.530	1.00
123_D	127_N	1.469	0.99
79_I	85_I	1.458	0.99
162_S	165_E	1.457	0.99
54_A	67_I	1.414	0.99
68_T	86_G	1.411	0.99
36_L	152_L	1.399	0.99
19_E	172_A	1.389	0.99
67_I	84_P	1.387	0.99
34_I	104_I	1.376	0.99
164_E	167_R	1.353	0.99
44_I	85_I	1.351	0.99
70_A	82_G	1.334	0.99
50_L	87_C	1.332	0.99
108_V	117_L	1.327	0.99
88_K	153_D	1.285	0.98
32_E	159_T	1.247	0.98
73_S	81_Q	1.228	0.98
17_M	25_V	1.213	0.98
14_K	18_T	1.170	0.97
5_H	94_E	1.167	0.97
54_A	58_A	1.165	0.97
34_I	173_F	1.155	0.97
52_N	56_D	1.154	0.97
135_Q	150_R	1.136	0.97
121_S	153_D	1.101	0.96
19_E	164_E	1.097	0.96
117_L	130_M	1.096	0.96
56_D	150_R	1.089	0.96
51_D	55_A	1.071	0.95
147_D	150_R	1.069	0.95
46_D	49_L	1.060	0.95
55_A	58_A	1.050	0.95
36_L	57_L	1.049	0.95
32_E	35_T	1.049	0.95
14_K	17_M	1.035	0.94
44_I	50_L	1.031	0.94
38_M	87_C	0.997	0.93
91_L	99_F	0.988	0.93
15_K	19_E	0.977	0.92
134_E	149_V	0.969	0.92
3_K	105_T	0.966	0.92
38_M	150_R	0.956	0.91
18_T	21_N	0.956	0.91
104_I	173_F	0.953	0.91
55_A	59_A	0.947	0.91
37_N	153_D	0.944	0.91
22_Y	27_Q	0.942	0.91
52_N	147_D	0.934	0.90
20_F	165_E	0.932	0.90
42_E	148_R	0.931	0.90
136_I	143_Y	0.929	0.90
40_V	50_L	0.917	0.90
19_E	171_A	0.916	0.90
136_I	149_V	0.915	0.90
44_I	79_I	0.910	0.89
158_T	166_G	0.902	0.89
119_A	178_R	0.902	0.89
13_V	17_M	0.901	0.89
54_A	87_C	0.894	0.88
31_V	34_I	0.893	0.88
9_K	14_K	0.889	0.88
31_V	100_F	0.888	0.88
52_N	143_Y	0.887	0.88
121_S	130_M	0.876	0.87
103_L	108_V	0.876	0.87
73_S	82_G	0.872	0.87
107_A	132_V	0.857	0.86
7_Y	173_F	0.856	0.86
132_V	153_D	0.842	0.85
100_F	173_F	0.840	0.85
143_Y	150_R	0.838	0.85
10_D	18_T	0.836	0.85
125_R	163_D	0.833	0.85
57_L	89_V	0.824	0.84
7_Y	174_D	0.823	0.84
42_E	150_R	0.820	0.84
44_I	83_Y	0.816	0.83
33_K	90_T	0.802	0.82
40_V	49_L	0.798	0.82
131_G	151_G	0.791	0.81
13_V	25_V	0.787	0.81
7_Y	15_K	0.786	0.81
33_K	92_R	0.779	0.80
98_E	101_E	0.775	0.80
74_V	129_S	0.761	0.79
47_K	84_P	0.752	0.78
66_L	88_K	0.750	0.78
31_V	96_M	0.746	0.77
58_A	61_S	0.744	0.77
118_S	121_S	0.741	0.77
54_A	65_P	0.738	0.77
121_S	128_Y	0.737	0.77
160_A	165_E	0.735	0.76
143_Y	147_D	0.734	0.76
107_A	137_I	0.727	0.76
5_H	93_G	0.724	0.75
6_D	9_K	0.723	0.75
53_A	87_C	0.720	0.75
49_L	150_R	0.715	0.74
25_V	28_V	0.711	0.74
36_L	103_L	0.710	0.74
160_A	166_G	0.710	0.74
129_S	153_D	0.707	0.74
99_F	138_F	0.698	0.73
44_I	129_S	0.693	0.72
34_I	156_I	0.690	0.72
70_A	79_I	0.683	0.71
46_D	50_L	0.683	0.71
10_D	14_K	0.682	0.71
38_M	56_D	0.680	0.71
39_G	86_G	0.678	0.70
19_E	22_Y	0.675	0.70
17_M	24_S	0.672	0.70
94_E	98_E	0.671	0.70
4_L	7_Y	0.660	0.68
5_H	17_M	0.651	0.67
3_K	98_E	0.648	0.67
145_K	148_R	0.646	0.67
79_I	83_Y	0.645	0.67
24_S	132_V	0.642	0.66
161_K	165_E	0.640	0.66
135_Q	156_I	0.638	0.66
122_F	127_N	0.638	0.66
56_D	147_D	0.637	0.66
156_I	173_F	0.635	0.65
68_T	74_V	0.634	0.65
23_N	27_Q	0.632	0.65
27_Q	160_A	0.631	0.65
17_M	20_F	0.630	0.65
40_V	58_A	0.627	0.64
47_K	178_R	0.626	0.64
13_V	172_A	0.626	0.64
53_A	57_L	0.626	0.64
12_V	20_F	0.623	0.64
41_G	80_R	0.617	0.63
93_G	117_L	0.615	0.63
120_K	164_E	0.612	0.63
124_G	158_T	0.606	0.62
134_E	144_D	0.605	0.62
132_V	154_I	0.605	0.62
4_L	104_I	0.604	0.62
33_K	157_T	0.602	0.61
42_E	46_D	0.597	0.61
76_G	79_I	0.596	0.61
35_T	88_K	0.594	0.60
9_K	17_M	0.593	0.60
117_L	128_Y	0.591	0.60
34_I	99_F	0.591	0.60
65_P	88_K	0.589	0.60
94_E	97_W	0.586	0.59
61_S	65_P	0.580	0.59
9_K	30_R	0.580	0.59
34_I	96_M	0.579	0.58
32_E	157_T	0.578	0.58
20_F	24_S	0.576	0.58
130_M	139_P	0.576	0.58
20_F	172_A	0.576	0.58
59_A	145_K	0.575	0.58
115_R	178_R	0.573	0.58
45_A	132_V	0.573	0.58
40_V	68_T	0.571	0.57
10_D	21_N	0.571	0.57
7_Y	10_D	0.570	0.57
46_D	175_F	0.570	0.57
9_K	12_V	0.568	0.57
45_A	76_G	0.568	0.57
150_R	153_D	0.567	0.57
5_H	8_Y	0.565	0.57
61_S	135_Q	0.564	0.56
26_M	38_M	0.552	0.55
44_I	47_K	0.550	0.55
36_L	99_F	0.549	0.54
45_A	178_R	0.549	0.54
106_I	132_V	0.547	0.54
45_A	175_F	0.546	0.54
156_I	175_F	0.545	0.54
158_T	169_L	0.544	0.54
16_L	172_A	0.544	0.54
63_Q	95_R	0.541	0.53
39_G	77_F	0.538	0.53
56_D	135_Q	0.538	0.53
17_M	21_N	0.537	0.53
108_V	130_M	0.537	0.53
29_P	158_T	0.535	0.53
80_R	144_D	0.535	0.53
102_R	173_F	0.535	0.53
57_L	61_S	0.535	0.53
16_L	19_E	0.532	0.52
102_R	140_E	0.531	0.52
103_L	117_L	0.530	0.52
121_S	157_T	0.528	0.52
9_K	15_K	0.528	0.52
122_F	170_L	0.528	0.52
11_E	164_E	0.527	0.51
46_D	147_D	0.525	0.51
143_Y	148_R	0.524	0.51
31_V	173_F	0.523	0.51
104_I	175_F	0.518	0.50
39_G	85_I	0.517	0.50
164_E	171_A	0.515	0.50
47_K	50_L	0.513	0.50
63_Q	92_R	0.512	0.49
29_P	140_E	0.511	0.49
38_M	129_S	0.510	0.49
14_K	132_V	0.508	0.49
63_Q	77_F	0.508	0.49
35_T	38_M	0.507	0.49
132_V	152_L	0.506	0.49
56_D	146_V	0.505	0.49
105_T	174_D	0.505	0.49
129_S	137_I	0.505	0.49
125_R	146_V	0.503	0.48
164_E	168_A	0.503	0.48
38_M	153_D	0.503	0.48
52_N	55_A	0.502	0.48
95_R	98_E	0.501	0.48
133_R	143_Y	0.500	0.48
73_S	83_Y	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1iq4A	1	1	100	0.014	Contact Map
3bboH	1	0.9777	100	0.014	Contact Map
4rb6G	1	1	100	0.021	Contact Map
4tp9F	1	0.9888	100	0.027	Contact Map
1vw4E	1	1	100	0.09	Contact Map
3j21E	1	0.9162	100	0.261	Contact Map
1vq8D	1	0.6648	100	0.268	Contact Map
3zf7L	1	0.8212	100	0.276	Contact Map
4ujqM	1	0.8212	100	0.283	Contact Map
1vx7G	1	0.6145	100	0.284	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0073 seconds.