SYH - ECOLI - GREMLIN Contacts

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SYH - Histidine--tRNA ligase

UniProt:	P60906	Sequences: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10453
Length:	424 (407)
Sequences:	8042 (5259)
Seq/√Len:	260.7

ECOLI - SYH SYP
BACSU - SYH HISZ SYP
HALSA - SYH
SULSO - SYH SYT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
396_T	409_A	3.730	1.00
408_T	418_H	3.274	1.00
164_E	254_N	3.253	1.00
31_N	154_A	3.202	1.00
293_E	299_A	3.072	1.00
401_D	404_S	3.028	1.00
107_Y	129_G	2.959	1.00
153_R	161_V	2.909	1.00
399_V	418_H	2.880	1.00
71_E	75_G	2.735	1.00
346_A	350_R	2.691	1.00
343_A	346_A	2.655	1.00
411_A	414_S	2.652	1.00
394_N	409_A	2.643	1.00
414_S	417_A	2.629	1.00
245_E	251_Y	2.548	1.00
396_T	411_A	2.361	1.00
390_S	394_N	2.340	1.00
398_V	407_Q	2.310	1.00
384_A	402_L	2.262	1.00
71_E	77_S	2.258	1.00
348_A	360_L	2.251	1.00
28_T	154_A	2.224	1.00
389_E	393_A	2.169	1.00
32_V	154_A	2.159	1.00
330_D	359_K	2.152	1.00
30_K	40_E	2.136	1.00
333_L	348_A	2.057	1.00
27_G	31_N	2.048	1.00
11_M	46_V	2.023	1.00
33_L	128_L	2.011	1.00
194_E	197_K	2.005	1.00
29_L	151_W	1.993	1.00
23_Q	26_E	1.983	1.00
339_D	393_A	1.973	1.00
264_Y	267_T	1.961	1.00
142_A	243_L	1.945	1.00
173_A	230_D	1.940	1.00
368_N	371_K	1.934	1.00
414_S	418_H	1.919	1.00
18_E	317_Q	1.869	1.00
134_G	141_D	1.855	1.00
49_T	53_K	1.837	1.00
130_C	144_L	1.809	1.00
237_F	253_V	1.808	1.00
189_K	192_L	1.804	1.00
69_T	77_S	1.798	1.00
25_I	313_V	1.790	1.00
179_D	183_A	1.789	1.00
373_F	386_V	1.773	1.00
331_I	358_V	1.766	1.00
343_A	392_V	1.758	1.00
330_D	358_V	1.757	1.00
21_I	317_Q	1.739	1.00
35_S	150_R	1.730	1.00
193_D	196_C	1.712	1.00
189_K	197_K	1.702	1.00
23_Q	40_E	1.700	1.00
41_I	88_C	1.696	1.00
230_D	233_S	1.685	1.00
180_A	228_Y	1.659	1.00
31_N	35_S	1.650	1.00
36_Y	150_R	1.647	1.00
348_A	362_T	1.647	1.00
390_S	393_A	1.643	1.00
24_R	28_T	1.643	1.00
41_I	91_A	1.636	1.00
38_Y	104_R	1.621	1.00
232_E	235_E	1.616	1.00
134_G	139_D	1.614	1.00
148_T	271_W	1.602	1.00
34_G	106_W	1.600	1.00
242_K	246_S	1.595	1.00
383_V	399_V	1.590	1.00
350_R	412_Q	1.586	1.00
35_S	154_A	1.577	1.00
186_E	201_Y	1.565	1.00
231_E	235_E	1.561	1.00
162_T	252_T	1.555	1.00
385_V	397_A	1.549	1.00
146_M	150_R	1.537	1.00
388_G	391_E	1.531	1.00
126_H	310_E	1.527	1.00
383_V	419_L	1.521	1.00
45_I	109_G	1.518	1.00
297_G	301_P	1.513	1.00
45_I	112_F	1.513	1.00
29_L	309_L	1.506	1.00
369_F	373_F	1.502	1.00
72_D	76_D	1.501	1.00
238_A	242_K	1.493	1.00
342_S	346_A	1.482	1.00
296_G	301_P	1.466	1.00
23_Q	30_K	1.448	1.00
54_R	93_I	1.446	1.00
150_R	349_E	1.439	1.00
49_T	79_T	1.419	1.00
348_A	352_R	1.417	1.00
335_A	344_A	1.406	1.00
339_D	389_E	1.394	1.00
198_R	202_T	1.389	1.00
397_A	412_Q	1.387	1.00
332_Y	376_A	1.387	1.00
81_R	109_G	1.385	1.00
335_A	372_Q	1.384	1.00
286_G	290_G	1.381	1.00
8_I	46_V	1.380	1.00
149_A	153_R	1.373	1.00
84_G	107_Y	1.371	1.00
239_G	243_L	1.370	1.00
415_V	419_L	1.366	1.00
110_P	124_Q	1.366	1.00
399_V	410_V	1.360	1.00
383_V	401_D	1.359	1.00
350_R	353_D	1.359	1.00
173_A	233_S	1.357	1.00
337_G	389_E	1.356	1.00
49_T	77_S	1.355	1.00
146_M	247_A	1.355	1.00
209_D	213_P	1.355	1.00
84_G	129_G	1.346	1.00
223_P	238_A	1.345	1.00
222_A	225_L	1.342	1.00
162_T	274_N	1.331	1.00
130_C	147_L	1.327	1.00
170_S	230_D	1.306	1.00
8_I	11_M	1.305	1.00
132_V	140_I	1.299	1.00
23_Q	27_G	1.283	1.00
148_T	283_C	1.278	1.00
331_I	351_L	1.277	1.00
206_R	209_D	1.275	1.00
21_I	313_V	1.274	1.00
398_V	409_A	1.270	1.00
234_R	238_A	1.266	1.00
246_S	342_S	1.259	1.00
17_G	20_A	1.247	1.00
354_E	416_A	1.244	1.00
241_C	245_E	1.241	1.00
217_A	220_N	1.240	1.00
349_E	353_D	1.238	1.00
213_P	217_A	1.232	1.00
316_V	326_D	1.231	1.00
395_G	413_D	1.223	1.00
195_D	198_R	1.209	1.00
26_E	42_R	1.208	1.00
239_G	242_K	1.208	1.00
104_R	361_M	1.198	1.00
242_K	245_E	1.196	1.00
196_C	210_S	1.196	1.00
128_L	309_L	1.189	1.00
23_Q	34_G	1.183	1.00
238_A	241_C	1.181	1.00
337_G	340_T	1.181	1.00
245_E	250_A	1.179	1.00
164_E	252_T	1.176	1.00
49_T	69_T	1.176	1.00
343_A	412_Q	1.166	1.00
22_W	126_H	1.165	1.00
89_V	292_V	1.163	1.00
331_I	385_V	1.160	1.00
149_A	163_L	1.152	1.00
333_L	344_A	1.143	1.00
334_V	369_F	1.142	1.00
206_R	211_K	1.140	1.00
367_G	371_K	1.138	1.00
286_G	302_A	1.137	1.00
208_L	211_K	1.133	1.00
84_G	111_M	1.125	1.00
350_R	416_A	1.124	1.00
196_C	199_R	1.122	1.00
73_R	114_H	1.121	1.00
122_Y	310_E	1.119	1.00
9_R	116_R	1.116	1.00
257_L	260_G	1.114	1.00
264_Y	269_F	1.113	1.00
331_I	360_L	1.110	1.00
89_V	133_F	1.107	1.00
231_E	234_R	1.107	1.00
26_E	30_K	1.103	1.00
233_S	237_F	1.102	1.00
19_T	23_Q	1.100	1.00
209_D	217_A	1.099	1.00
235_E	239_G	1.095	1.00
241_C	251_Y	1.090	1.00
29_L	128_L	1.089	1.00
36_Y	147_L	1.080	1.00
373_F	377_D	1.073	1.00
264_Y	268_V	1.072	1.00
76_D	114_H	1.072	1.00
237_F	240_L	1.068	1.00
38_Y	132_V	1.067	1.00
22_W	310_E	1.065	1.00
276_L	279_Q	1.062	1.00
176_N	179_D	1.060	1.00
8_I	78_L	1.056	1.00
242_K	342_S	1.053	1.00
194_E	199_R	1.047	1.00
243_L	246_S	1.047	1.00
350_R	354_E	1.047	1.00
92_G	105_L	1.046	1.00
390_S	409_A	1.046	1.00
382_R	401_D	1.044	1.00
206_R	210_S	1.044	1.00
45_I	124_Q	1.039	1.00
40_E	106_W	1.036	1.00
241_C	253_V	1.028	1.00
186_E	189_K	1.027	1.00
125_F	306_A	1.027	1.00
399_V	415_V	1.023	1.00
215_V	219_L	1.017	1.00
336_S	369_F	1.014	1.00
30_K	108_I	1.012	1.00
216_Q	219_L	1.012	1.00
400_K	407_Q	1.010	1.00
412_Q	416_A	1.010	1.00
333_L	347_L	1.007	1.00
234_R	237_F	1.002	1.00
189_K	201_Y	1.000	1.00
397_A	410_V	1.000	1.00
53_K	77_S	0.998	1.00
189_K	200_M	0.997	1.00
410_V	415_V	0.996	1.00
261_L	264_Y	0.996	1.00
185_L	207_V	0.994	1.00
211_K	214_E	0.986	1.00
401_D	406_E	0.982	1.00
354_E	357_G	0.981	1.00
193_D	210_S	0.981	1.00
12_N	310_E	0.981	1.00
209_D	215_V	0.977	1.00
46_V	80_L	0.976	1.00
50_P	53_K	0.974	1.00
15_L	91_A	0.973	1.00
207_V	211_K	0.969	1.00
214_E	217_A	0.967	1.00
345_M	349_E	0.963	1.00
172_E	176_N	0.960	1.00
343_A	387_L	0.955	1.00
20_A	34_G	0.955	1.00
335_A	362_T	0.948	1.00
188_H	191_K	0.944	1.00
149_A	161_V	0.943	1.00
400_K	405_G	0.942	1.00
243_L	247_A	0.938	1.00
29_L	33_L	0.937	1.00
45_I	110_P	0.936	1.00
170_S	173_A	0.935	1.00
14_Y	22_W	0.934	1.00
246_S	249_I	0.926	1.00
164_E	272_V	0.923	1.00
197_K	201_Y	0.922	1.00
145_I	163_L	0.921	1.00
210_S	219_L	0.919	1.00
340_T	343_A	0.919	1.00
36_Y	104_R	0.918	1.00
377_D	400_K	0.914	1.00
43_L	87_G	0.911	1.00
334_V	384_A	0.909	1.00
382_R	403_R	0.903	1.00
212_N	215_V	0.902	1.00
24_R	359_K	0.901	1.00
8_I	48_Q	0.898	1.00
298_R	301_P	0.892	1.00
119_K	122_Y	0.892	1.00
27_G	30_K	0.892	1.00
12_N	18_E	0.892	1.00
332_Y	381_A	0.890	1.00
137_G	302_A	0.882	1.00
257_L	268_V	0.881	1.00
69_T	79_T	0.873	1.00
143_E	352_R	0.872	1.00
28_T	31_N	0.872	1.00
397_A	415_V	0.871	1.00
178_R	181_L	0.870	1.00
377_D	402_L	0.870	1.00
335_A	341_Q	0.870	1.00
245_E	249_I	0.869	1.00
70_F	78_L	0.867	1.00
204_P	209_D	0.864	1.00
151_W	307_M	0.863	1.00
296_G	300_T	0.861	1.00
210_S	215_V	0.858	1.00
133_F	292_V	0.854	1.00
196_C	201_Y	0.852	1.00
260_G	263_Y	0.852	1.00
287_R	291_L	0.851	0.99
237_F	241_C	0.850	0.99
104_R	130_C	0.850	0.99
170_S	233_S	0.848	0.99
236_H	240_L	0.846	0.99
215_V	220_N	0.846	0.99
205_L	211_K	0.845	0.99
205_L	208_L	0.845	0.99
84_G	109_G	0.844	0.99
205_L	209_D	0.844	0.99
204_P	211_K	0.843	0.99
385_V	399_V	0.841	0.99
112_F	124_Q	0.841	0.99
206_R	213_P	0.835	0.99
346_A	412_Q	0.835	0.99
28_T	155_L	0.834	0.99
88_C	129_G	0.833	0.99
36_Y	143_E	0.832	0.99
211_K	215_V	0.831	0.99
314_L	317_Q	0.831	0.99
231_E	238_A	0.830	0.99
181_L	184_F	0.830	0.99
46_V	78_L	0.829	0.99
183_A	186_E	0.828	0.99
178_R	182_V	0.828	0.99
261_L	269_F	0.826	0.99
150_R	153_R	0.826	0.99
258_V	261_L	0.824	0.99
194_E	201_Y	0.822	0.99
192_L	199_R	0.820	0.99
259_R	270_E	0.819	0.99
27_G	34_G	0.816	0.99
371_K	374_A	0.813	0.99
144_L	303_V	0.811	0.99
333_L	360_L	0.810	0.99
340_T	392_V	0.810	0.99
207_V	220_N	0.809	0.99
152_W	283_C	0.807	0.99
208_L	213_P	0.806	0.99
385_V	415_V	0.806	0.99
108_I	128_L	0.806	0.99
260_G	265_N	0.805	0.99
121_R	308_G	0.804	0.99
410_V	418_H	0.798	0.99
43_L	88_C	0.798	0.99
81_R	84_G	0.798	0.99
358_V	419_L	0.797	0.99
22_W	42_R	0.796	0.99
58_E	79_T	0.795	0.99
411_A	415_V	0.794	0.99
285_G	288_Y	0.791	0.99
216_Q	220_N	0.791	0.99
244_L	249_I	0.791	0.99
297_G	300_T	0.789	0.99
237_F	249_I	0.788	0.99
384_A	407_Q	0.786	0.99
232_E	236_H	0.785	0.99
308_G	311_R	0.783	0.99
149_A	250_A	0.783	0.99
150_R	154_A	0.782	0.99
210_S	213_P	0.782	0.99
30_K	106_W	0.782	0.99
233_S	236_H	0.780	0.99
150_R	353_D	0.777	0.99
207_V	213_P	0.776	0.99
26_E	40_E	0.776	0.99
19_T	22_W	0.776	0.99
158_S	319_V	0.774	0.99
194_E	198_R	0.774	0.99
173_A	176_N	0.774	0.99
209_D	218_L	0.774	0.99
30_K	34_G	0.773	0.99
221_D	224_A	0.773	0.99
53_K	59_V	0.772	0.99
377_D	384_A	0.772	0.99
228_Y	231_E	0.770	0.99
213_P	216_Q	0.766	0.99
361_M	381_A	0.764	0.99
387_L	397_A	0.759	0.99
226_G	229_L	0.759	0.99
20_A	39_S	0.759	0.99
26_E	309_L	0.757	0.99
204_P	207_V	0.752	0.99
259_R	262_D	0.749	0.99
7_A	94_E	0.749	0.99
32_V	151_W	0.747	0.99
258_V	262_D	0.746	0.99
182_V	186_E	0.746	0.99
207_V	218_L	0.745	0.99
263_Y	268_V	0.744	0.99
234_R	241_C	0.743	0.99
166_N	169_G	0.743	0.99
195_D	199_R	0.743	0.99
232_E	237_F	0.743	0.99
258_V	271_W	0.742	0.99
35_S	352_R	0.740	0.99
161_V	271_W	0.737	0.99
363_N	367_G	0.734	0.99
12_N	122_Y	0.731	0.98
46_V	68_Y	0.730	0.98
74_N	114_H	0.729	0.98
260_G	264_Y	0.729	0.98
264_Y	270_E	0.727	0.98
209_D	212_N	0.724	0.98
196_C	215_V	0.723	0.98
274_N	277_G	0.721	0.98
28_T	32_V	0.721	0.98
35_S	358_V	0.719	0.98
225_L	230_D	0.718	0.98
88_C	105_L	0.718	0.98
19_T	42_R	0.716	0.98
369_F	386_V	0.716	0.98
192_L	200_M	0.706	0.98
182_V	201_Y	0.702	0.98
45_I	80_L	0.699	0.98
370_K	374_A	0.698	0.98
32_V	36_Y	0.697	0.98
235_E	238_A	0.696	0.98
233_S	238_A	0.694	0.98
32_V	150_R	0.692	0.98
145_I	149_A	0.691	0.98
96_G	103_Q	0.691	0.98
228_Y	232_E	0.689	0.98
200_M	207_V	0.688	0.98
266_R	271_W	0.688	0.98
196_C	200_M	0.685	0.98
211_K	216_Q	0.685	0.98
350_R	413_D	0.684	0.98
34_G	359_K	0.683	0.98
125_F	311_R	0.683	0.98
324_K	383_V	0.682	0.98
340_T	389_E	0.678	0.98
186_E	192_L	0.676	0.97
11_M	43_L	0.675	0.97
26_E	108_I	0.671	0.97
295_L	298_R	0.670	0.97
333_L	362_T	0.669	0.97
24_R	27_G	0.669	0.97
115_E	311_R	0.667	0.97
263_Y	270_E	0.667	0.97
236_H	239_G	0.665	0.97
273_T	276_L	0.665	0.97
163_L	271_W	0.664	0.97
233_S	240_L	0.663	0.97
9_R	117_P	0.661	0.97
24_R	323_F	0.660	0.97
192_L	198_R	0.655	0.97
231_E	243_L	0.655	0.97
207_V	215_V	0.654	0.97
227_D	230_D	0.654	0.97
330_D	382_R	0.652	0.97
341_Q	345_M	0.652	0.97
347_L	350_R	0.651	0.97
192_L	201_Y	0.650	0.97
210_S	216_Q	0.649	0.97
136_Q	301_P	0.647	0.97
408_T	414_S	0.647	0.97
92_G	96_G	0.645	0.97
145_I	177_Y	0.644	0.97
152_W	312_L	0.643	0.97
240_L	243_L	0.642	0.97
212_N	216_Q	0.642	0.97
296_G	299_A	0.636	0.96
200_M	203_N	0.634	0.96
190_E	193_D	0.634	0.96
213_P	218_L	0.634	0.96
321_P	324_K	0.633	0.96
115_E	308_G	0.633	0.96
259_R	264_Y	0.630	0.96
266_R	269_F	0.630	0.96
253_V	257_L	0.626	0.96
211_K	219_L	0.625	0.96
14_Y	18_E	0.625	0.96
192_L	197_K	0.624	0.96
199_R	203_N	0.624	0.96
186_E	200_M	0.623	0.96
217_A	221_D	0.623	0.96
83_E	86_A	0.621	0.96
239_G	244_L	0.621	0.96
257_L	263_Y	0.619	0.96
261_L	265_N	0.618	0.96
209_D	214_E	0.618	0.96
290_G	293_E	0.617	0.96
145_I	282_V	0.616	0.96
289_D	294_Q	0.616	0.96
347_L	412_Q	0.616	0.96
32_V	35_S	0.614	0.96
374_A	377_D	0.614	0.96
142_A	247_A	0.611	0.95
199_R	202_T	0.611	0.95
408_T	412_Q	0.611	0.95
46_V	70_F	0.610	0.95
347_L	387_L	0.610	0.95
115_E	121_R	0.610	0.95
41_I	105_L	0.608	0.95
192_L	267_T	0.607	0.95
374_A	378_K	0.607	0.95
157_I	315_L	0.606	0.95
140_I	284_A	0.602	0.95
212_N	219_L	0.600	0.95
239_G	245_E	0.600	0.95
263_Y	266_R	0.599	0.95
92_G	300_T	0.598	0.95
236_H	266_R	0.597	0.95
146_M	149_A	0.597	0.95
258_V	264_Y	0.596	0.95
20_A	359_K	0.596	0.95
66_E	69_T	0.593	0.95
275_S	278_S	0.591	0.95
324_K	330_D	0.591	0.95
63_V	66_E	0.590	0.95
42_R	109_G	0.590	0.95
239_G	246_S	0.589	0.94
257_L	261_L	0.589	0.94
232_E	243_L	0.589	0.94
404_S	407_Q	0.589	0.94
215_V	218_L	0.588	0.94
152_W	161_V	0.588	0.94
316_V	320_N	0.587	0.94
239_G	249_I	0.586	0.94
92_G	101_Q	0.583	0.94
240_L	244_L	0.581	0.94
338_A	341_Q	0.579	0.94
191_K	218_L	0.579	0.94
354_E	417_A	0.579	0.94
113_R	125_F	0.577	0.94
257_L	271_W	0.577	0.94
333_L	385_V	0.576	0.94
38_Y	130_C	0.575	0.94
88_C	133_F	0.575	0.94
238_A	243_L	0.573	0.94
214_E	219_L	0.573	0.94
261_L	270_E	0.573	0.94
168_I	177_Y	0.572	0.94
90_R	94_E	0.569	0.93
174_R	177_Y	0.568	0.93
36_Y	352_R	0.568	0.93
262_D	276_L	0.568	0.93
184_F	188_H	0.567	0.93
19_T	40_E	0.567	0.93
93_I	295_L	0.567	0.93
331_I	415_V	0.566	0.93
210_S	214_E	0.564	0.93
352_R	360_L	0.564	0.93
121_R	125_F	0.563	0.93
273_T	277_G	0.562	0.93
36_Y	144_L	0.561	0.93
214_E	218_L	0.561	0.93
185_L	203_N	0.560	0.93
205_L	210_S	0.560	0.93
346_A	349_E	0.559	0.93
241_C	244_L	0.559	0.93
88_C	107_Y	0.558	0.93
168_I	172_E	0.558	0.93
110_P	126_H	0.558	0.93
92_G	98_L	0.557	0.93
104_R	143_E	0.556	0.93
386_V	407_Q	0.555	0.93
344_A	362_T	0.555	0.93
55_A	63_V	0.553	0.92
226_G	231_E	0.553	0.92
271_W	283_C	0.551	0.92
176_N	229_L	0.551	0.92
123_R	308_G	0.550	0.92
334_V	372_Q	0.549	0.92
258_V	263_Y	0.548	0.92
55_A	284_A	0.548	0.92
395_G	412_Q	0.545	0.92
254_N	257_L	0.545	0.92
247_A	345_M	0.544	0.92
90_R	93_I	0.544	0.92
233_S	241_C	0.543	0.92
351_L	415_V	0.543	0.92
258_V	267_T	0.543	0.92
181_L	185_L	0.539	0.91
130_C	305_F	0.538	0.91
244_L	248_G	0.537	0.91
283_C	307_M	0.537	0.91
242_K	247_A	0.536	0.91
373_F	402_L	0.535	0.91
51_L	90_R	0.535	0.91
188_H	200_M	0.534	0.91
233_S	243_L	0.534	0.91
263_Y	267_T	0.534	0.91
257_L	264_Y	0.534	0.91
292_V	300_T	0.533	0.91
255_Q	264_Y	0.531	0.91
401_D	405_G	0.531	0.91
260_G	270_E	0.529	0.91
141_D	144_L	0.527	0.91
111_M	127_Q	0.526	0.90
260_G	268_V	0.526	0.90
138_P	236_H	0.523	0.90
193_D	215_V	0.521	0.90
330_D	381_A	0.521	0.90
331_I	383_V	0.521	0.90
333_L	387_L	0.520	0.90
167_S	171_L	0.520	0.90
91_A	95_H	0.520	0.90
393_A	396_T	0.519	0.90
373_F	384_A	0.519	0.90
153_R	158_S	0.519	0.90
332_Y	335_A	0.518	0.90
51_L	295_L	0.517	0.90
264_Y	271_W	0.516	0.90
92_G	133_F	0.515	0.89
259_R	263_Y	0.515	0.89
401_D	407_Q	0.514	0.89
272_V	277_G	0.514	0.89
329_V	381_A	0.513	0.89
189_K	193_D	0.512	0.89
132_V	144_L	0.512	0.89
227_D	231_E	0.511	0.89
22_W	26_E	0.510	0.89
205_L	213_P	0.507	0.89
238_A	245_E	0.507	0.89
396_T	412_Q	0.507	0.89
206_R	215_V	0.506	0.89
290_G	299_A	0.505	0.89
256_R	260_G	0.505	0.89
234_R	243_L	0.505	0.89
397_A	416_A	0.503	0.88
255_Q	262_D	0.503	0.88
265_N	277_G	0.500	0.88

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1httA	2	0.8608	100	0.181	Contact Map
1h4vB	2	0.9458	100	0.197	Contact Map
1qe0A	2	0.908	100	0.213	Contact Map
4e51A	2	0.9646	100	0.22	Contact Map
4phcA	2	0.9693	100	0.223	Contact Map
1wu7A	2	0.9575	100	0.224	Contact Map
3netA	2	0.9458	100	0.224	Contact Map
3lc0A	2	0.9363	100	0.229	Contact Map
4g84A	2	0.9599	100	0.237	Contact Map
3od1A	2	0.8632	100	0.281	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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