ADIC - ECOLI - GREMLIN Contacts

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ADIC - Arginine/agmatine antiporter

UniProt:	P60061	Sequences: MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIYGWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNIAMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALIPIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILMTIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTTIAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12462
Length:	445 (413)
Sequences:	24681 (15895)
Seq/√Len:	782.2

ECOLI - ADIC POTE CADB FRLA PUUP PROY ANSP PLAP YIFK AROP MMUP LYSP YCAM GABP ARCD GADC CYCA PHEP YGJI YBAT YJEH YJEM TNAB
BACSU - YBXG ASPP YTNA HUTM GABP ROCC YBGF YBEC YHDG STET ARCD YDGF YVBW YCGH YFNA ROCE AAPA YECA YDAO GERAB GERBB YNDE GERKB
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97U05 Q7LXI7 Q97XM0 Q97X49 Q97ZB5 Q97WS3 Q97U33 Q97Z63 Q97WD4 Q97VA6 Q97VA8 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
137_V	331_G	4.396	1.00
313_I	325_A	4.312	1.00
374_L	378_G	3.349	1.00
50_I	236_A	3.226	1.00
316_R	325_A	3.128	1.00
222_R	226_I	2.978	1.00
366_L	395_F	2.912	1.00
11_G	218_K	2.861	1.00
219_N	222_R	2.727	1.00
74_Y	307_D	2.687	1.00
217_V	223_N	2.687	1.00
90_N	304_A	2.604	1.00
305_A	315_A	2.568	1.00
169_G	245_A	2.565	1.00
318_N	324_V	2.562	1.00
313_I	316_R	2.481	1.00
130_V	335_T	2.479	1.00
62_K	376_G	2.460	1.00
16_T	230_G	2.415	1.00
12_L	230_G	2.374	1.00
167_V	171_F	2.372	1.00
215_G	306_D	2.290	1.00
264_D	267_R	2.287	1.00
78_R	86_G	2.234	1.00
369_C	394_A	2.220	1.00
12_L	223_N	2.201	1.00
328_I	332_I	2.167	1.00
302_K	306_D	2.149	1.00
216_V	299_Q	2.133	1.00
134_W	335_T	2.115	1.00
422_A	426_L	2.098	1.00
137_V	327_L	2.097	1.00
15_V	217_V	2.088	1.00
141_I	324_V	2.084	1.00
392_T	396_L	2.082	1.00
12_L	16_T	2.080	1.00
138_L	142_V	2.073	1.00
81_F	374_L	2.062	1.00
145_K	149_R	2.048	1.00
129_C	338_Q	2.004	1.00
254_A	268_M	1.989	1.00
273_T	277_I	1.978	1.00
59_V	369_C	1.974	1.00
226_I	230_G	1.969	1.00
156_V	160_I	1.939	1.00
308_G	312_P	1.935	1.00
78_R	83_P	1.913	1.00
314_F	329_I	1.912	1.00
130_V	338_Q	1.911	1.00
11_G	14_P	1.899	1.00
416_T	420_I	1.894	1.00
94_W	330_V	1.893	1.00
81_F	370_A	1.856	1.00
251_P	254_A	1.853	1.00
51_I	55_G	1.840	1.00
389_A	393_I	1.830	1.00
264_D	268_M	1.807	1.00
6_D	317_V	1.800	1.00
14_P	152_A	1.751	1.00
219_N	223_N	1.749	1.00
370_A	395_F	1.748	1.00
134_W	331_G	1.737	1.00
35_L	42_A	1.729	1.00
414_F	418_M	1.729	1.00
318_N	322_T	1.706	1.00
105_V	290_L	1.689	1.00
140_N	291_G	1.683	1.00
396_L	400_W	1.678	1.00
77_A	89_T	1.676	1.00
101_N	334_M	1.662	1.00
52_G	397_Y	1.650	1.00
229_I	233_L	1.650	1.00
45_G	196_T	1.649	1.00
133_L	334_M	1.634	1.00
16_T	234_I	1.634	1.00
374_L	377_H	1.620	1.00
160_I	164_G	1.619	1.00
141_I	328_I	1.615	1.00
320_A	324_V	1.602	1.00
112_L	128_T	1.581	1.00
89_T	367_Y	1.578	1.00
10_V	14_P	1.569	1.00
82_G	85_L	1.543	1.00
124_V	127_I	1.536	1.00
19_V	231_G	1.529	1.00
233_L	237_V	1.522	1.00
105_V	133_L	1.488	1.00
142_V	320_A	1.472	1.00
410_V	413_S	1.468	1.00
267_R	275_G	1.458	1.00
258_S	261_P	1.458	1.00
400_W	404_G	1.456	1.00
49_T	200_T	1.452	1.00
137_V	328_I	1.448	1.00
302_K	317_V	1.442	1.00
213_A	295_L	1.441	1.00
108_G	132_V	1.429	1.00
301_A	326_G	1.427	1.00
297_A	330_V	1.424	1.00
77_A	367_Y	1.421	1.00
325_A	329_I	1.419	1.00
161_P	281_C	1.418	1.00
276_A	280_F	1.417	1.00
7_A	321_G	1.406	1.00
258_S	264_D	1.406	1.00
170_W	245_A	1.402	1.00
57_S	232_V	1.393	1.00
91_V	420_I	1.387	1.00
55_G	393_I	1.387	1.00
312_P	315_A	1.383	1.00
14_P	148_T	1.383	1.00
370_A	374_L	1.378	1.00
57_S	228_T	1.378	1.00
133_L	331_G	1.377	1.00
219_N	226_I	1.373	1.00
312_P	316_R	1.368	1.00
159_L	163_V	1.359	1.00
380_F	384_R	1.359	1.00
316_R	324_V	1.359	1.00
70_P	215_G	1.356	1.00
415_V	419_V	1.354	1.00
425_A	429_N	1.343	1.00
130_V	134_W	1.341	1.00
123_L	127_I	1.338	1.00
67_D	79_R	1.336	1.00
173_F	248_G	1.334	1.00
108_G	283_A	1.334	1.00
81_F	85_L	1.327	1.00
220_P	225_P	1.304	1.00
385_P	388_L	1.303	1.00
223_N	226_I	1.302	1.00
166_A	241_L	1.302	1.00
423_M	427_N	1.302	1.00
298_G	327_L	1.295	1.00
267_R	272_D	1.291	1.00
237_V	241_L	1.290	1.00
43_I	244_T	1.290	1.00
56_L	369_C	1.286	1.00
270_L	274_A	1.280	1.00
51_I	393_I	1.273	1.00
387_Y	391_T	1.271	1.00
30_L	107_I	1.269	1.00
389_A	392_T	1.266	1.00
189_T	192_A	1.266	1.00
388_L	392_T	1.262	1.00
379_H	382_K	1.260	1.00
6_D	302_K	1.252	1.00
75_A	79_R	1.252	1.00
58_M	229_I	1.251	1.00
420_I	423_M	1.247	1.00
10_V	15_V	1.246	1.00
136_F	290_L	1.246	1.00
80_C	371_A	1.242	1.00
406_G	409_E	1.240	1.00
104_M	289_S	1.235	1.00
10_V	148_T	1.234	1.00
12_L	226_I	1.229	1.00
412_W	415_V	1.228	1.00
169_G	249_M	1.213	1.00
421_T	425_A	1.211	1.00
418_M	422_A	1.207	1.00
94_W	301_A	1.207	1.00
386_A	390_V	1.204	1.00
23_I	235_A	1.202	1.00
423_M	426_L	1.199	1.00
84_F	427_N	1.197	1.00
13_I	17_L	1.194	1.00
426_L	429_N	1.189	1.00
413_S	417_L	1.186	1.00
411_M	415_V	1.179	1.00
165_I	169_G	1.179	1.00
301_A	310_F	1.173	1.00
377_H	380_F	1.162	1.00
62_K	65_F	1.161	1.00
15_V	227_A	1.159	1.00
69_S	75_A	1.158	1.00
410_V	414_F	1.156	1.00
126_T	130_V	1.148	1.00
218_K	223_N	1.146	1.00
411_M	414_F	1.137	1.00
60_Y	73_S	1.129	1.00
306_D	315_A	1.124	1.00
325_A	328_I	1.122	1.00
398_C	401_A	1.121	1.00
394_A	398_C	1.120	1.00
366_L	399_I	1.117	1.00
139_L	150_V	1.117	1.00
77_A	85_L	1.099	1.00
36_A	42_A	1.098	1.00
18_M	213_A	1.097	1.00
79_R	379_H	1.096	1.00
64_S	76_Y	1.093	1.00
174_R	177_T	1.091	1.00
399_I	403_V	1.086	1.00
380_F	383_A	1.084	1.00
9_K	218_K	1.084	1.00
127_I	131_V	1.083	1.00
19_V	210_A	1.077	1.00
137_V	141_I	1.069	1.00
164_G	168_F	1.069	1.00
109_V	128_T	1.062	1.00
20_S	234_I	1.059	1.00
332_I	336_I	1.056	1.00
87_Y	91_V	1.055	1.00
251_P	268_M	1.054	1.00
415_V	418_M	1.054	1.00
149_R	153_V	1.053	1.00
150_V	154_A	1.042	1.00
131_V	135_I	1.040	1.00
66_L	382_K	1.035	1.00
410_V	415_V	1.033	1.00
151_Q	291_G	1.032	1.00
317_V	321_G	1.031	1.00
47_L	240_V	1.024	1.00
260_S	264_D	1.023	1.00
69_S	79_R	1.014	1.00
59_V	391_T	1.014	1.00
66_L	384_R	1.014	1.00
419_V	423_M	1.011	1.00
373_L	392_T	1.004	1.00
74_Y	303_A	1.003	1.00
20_S	235_A	1.000	1.00
163_V	167_V	0.996	1.00
190_F	193_I	0.992	1.00
379_H	384_R	0.992	1.00
395_F	399_I	0.992	1.00
194_Q	400_W	0.989	1.00
134_W	138_L	0.987	1.00
144_P	295_L	0.978	1.00
413_S	416_T	0.977	1.00
403_V	407_A	0.976	1.00
415_V	422_A	0.974	1.00
135_I	287_L	0.973	1.00
175_G	178_Y	0.960	1.00
214_A	224_V	0.960	1.00
381_G	384_R	0.950	1.00
272_D	276_A	0.949	1.00
394_A	397_Y	0.942	1.00
413_S	422_A	0.939	1.00
166_A	245_A	0.931	1.00
84_F	88_Q	0.928	1.00
165_I	266_A	0.927	1.00
369_C	395_F	0.926	1.00
249_M	265_A	0.924	1.00
141_I	318_N	0.924	1.00
112_L	116_F	0.923	1.00
174_R	178_Y	0.922	1.00
400_W	403_V	0.917	1.00
141_I	322_T	0.916	1.00
171_F	175_G	0.915	1.00
154_A	288_G	0.908	1.00
386_A	389_A	0.908	1.00
205_I	361_T	0.904	1.00
366_L	370_A	0.901	1.00
43_I	247_M	0.900	1.00
136_F	291_G	0.899	1.00
244_T	248_G	0.898	1.00
391_T	398_C	0.896	1.00
402_V	405_S	0.895	1.00
294_T	331_G	0.892	1.00
180_A	183_N	0.892	1.00
318_N	321_G	0.890	1.00
103_A	354_S	0.890	1.00
423_M	429_N	0.890	1.00
17_L	152_A	0.889	1.00
391_T	395_F	0.889	1.00
411_M	416_T	0.888	1.00
109_V	129_C	0.886	1.00
128_T	131_V	0.886	1.00
9_K	145_K	0.885	1.00
372_L	391_T	0.884	1.00
208_E	212_V	0.884	1.00
405_S	408_K	0.881	1.00
420_I	424_Y	0.881	1.00
71_G	74_Y	0.880	1.00
416_T	423_M	0.880	1.00
190_F	194_Q	0.879	1.00
376_G	380_F	0.878	1.00
71_G	75_A	0.874	1.00
85_L	367_Y	0.869	1.00
91_V	310_F	0.869	1.00
314_F	325_A	0.867	1.00
414_F	417_L	0.865	1.00
195_S	199_V	0.864	1.00
103_A	202_W	0.857	1.00
159_L	238_C	0.856	1.00
78_R	307_D	0.855	1.00
50_I	204_F	0.853	1.00
14_P	149_R	0.852	1.00
236_A	240_V	0.851	1.00
230_G	234_I	0.851	1.00
44_Y	193_I	0.844	1.00
158_A	285_G	0.842	1.00
331_G	335_T	0.835	1.00
209_S	296_L	0.835	1.00
324_V	328_I	0.835	1.00
55_G	390_V	0.827	1.00
166_A	170_W	0.825	1.00
366_L	398_C	0.824	1.00
359_I	413_S	0.822	1.00
13_I	152_A	0.822	1.00
410_V	417_L	0.819	1.00
424_Y	428_Y	0.819	1.00
24_M	27_G	0.813	1.00
410_V	423_M	0.810	1.00
6_D	216_V	0.808	1.00
410_V	424_Y	0.805	1.00
12_L	227_A	0.804	1.00
310_F	314_F	0.804	1.00
138_L	141_I	0.801	1.00
108_G	286_C	0.797	1.00
44_Y	48_V	0.796	1.00
413_S	418_M	0.795	1.00
77_A	371_A	0.795	1.00
54_L	58_M	0.795	1.00
356_V	360_F	0.794	1.00
123_L	126_T	0.793	1.00
149_R	152_A	0.792	1.00
108_G	287_L	0.790	1.00
415_V	420_I	0.784	1.00
372_L	376_G	0.781	1.00
173_F	245_A	0.777	1.00
225_P	228_T	0.775	1.00
66_L	380_F	0.773	1.00
373_L	377_H	0.773	1.00
54_L	229_I	0.773	1.00
405_S	409_E	0.770	1.00
106_V	353_V	0.769	1.00
6_D	299_Q	0.769	1.00
112_L	283_A	0.767	1.00
55_G	59_V	0.762	1.00
136_F	294_T	0.761	1.00
271_G	274_A	0.758	1.00
178_Y	248_G	0.756	1.00
417_L	421_T	0.756	1.00
63_M	372_L	0.755	1.00
130_V	339_L	0.755	1.00
81_F	371_A	0.754	1.00
171_F	174_R	0.751	1.00
100_G	357_S	0.749	1.00
424_Y	427_N	0.748	1.00
9_K	144_P	0.747	1.00
179_M	183_N	0.744	1.00
371_A	375_L	0.742	1.00
319_K	324_V	0.742	1.00
395_F	398_C	0.742	1.00
133_L	338_Q	0.742	1.00
170_W	241_L	0.742	1.00
47_L	51_I	0.741	1.00
377_H	388_L	0.740	1.00
142_V	146_M	0.738	1.00
425_A	428_Y	0.737	1.00
412_W	416_T	0.736	1.00
219_N	225_P	0.734	1.00
140_N	327_L	0.731	1.00
126_T	338_Q	0.729	1.00
183_N	186_G	0.728	1.00
56_L	398_C	0.727	1.00
421_T	424_Y	0.724	1.00
332_I	335_T	0.724	1.00
60_Y	368_T	0.718	1.00
410_V	429_N	0.717	1.00
391_T	394_A	0.716	1.00
16_T	227_A	0.713	1.00
166_A	242_S	0.711	1.00
305_A	314_F	0.709	1.00
313_I	329_I	0.707	1.00
386_A	391_T	0.707	1.00
100_G	103_A	0.706	1.00
180_A	184_V	0.706	1.00
53_A	207_V	0.705	1.00
413_S	420_I	0.705	1.00
314_F	326_G	0.704	1.00
298_G	326_G	0.704	1.00
74_Y	78_R	0.703	1.00
415_V	426_L	0.702	1.00
38_T	195_S	0.702	1.00
410_V	425_A	0.701	1.00
13_I	149_R	0.698	1.00
63_M	76_Y	0.695	1.00
413_S	427_N	0.693	1.00
416_T	419_V	0.692	1.00
403_V	406_G	0.692	1.00
84_F	421_T	0.692	1.00
98_W	333_L	0.691	1.00
44_Y	47_L	0.691	1.00
113_S	117_P	0.690	1.00
24_M	158_A	0.690	1.00
422_A	425_A	0.689	1.00
109_V	125_L	0.689	1.00
301_A	329_I	0.689	1.00
140_N	295_L	0.687	1.00
273_T	276_A	0.687	1.00
294_T	298_G	0.686	1.00
148_T	152_A	0.686	1.00
16_T	19_V	0.684	1.00
93_Y	97_C	0.683	1.00
410_V	427_N	0.683	1.00
205_I	365_Y	0.683	1.00
102_I	337_F	0.682	1.00
373_L	388_L	0.681	1.00
241_L	245_A	0.680	1.00
396_L	399_I	0.678	1.00
23_I	231_G	0.675	1.00
141_I	320_A	0.675	1.00
401_A	404_G	0.674	1.00
42_A	243_T	0.673	1.00
412_W	424_Y	0.671	1.00
299_Q	302_K	0.669	1.00
418_M	421_T	0.667	1.00
401_A	405_S	0.663	1.00
64_S	224_V	0.662	1.00
109_V	112_L	0.659	1.00
416_T	424_Y	0.657	1.00
171_F	176_E	0.657	1.00
82_G	428_Y	0.657	1.00
414_F	423_M	0.655	1.00
413_S	423_M	0.655	1.00
242_S	262_F	0.655	1.00
141_I	327_L	0.650	1.00
22_N	293_W	0.649	1.00
22_N	292_G	0.648	1.00
100_G	104_M	0.648	1.00
80_C	374_L	0.647	1.00
419_V	427_N	0.647	1.00
261_P	266_A	0.647	1.00
410_V	420_I	0.646	1.00
146_M	149_R	0.645	1.00
96_A	361_T	0.644	1.00
168_F	172_W	0.643	1.00
9_K	13_I	0.642	1.00
392_T	395_F	0.638	1.00
179_M	182_W	0.638	1.00
157_L	281_C	0.638	1.00
419_V	422_A	0.637	1.00
180_A	185_S	0.637	1.00
113_S	125_L	0.636	1.00
215_G	302_K	0.636	1.00
24_M	238_C	0.635	1.00
424_Y	429_N	0.634	1.00
99_I	356_V	0.633	1.00
423_M	428_Y	0.633	1.00
104_M	290_L	0.633	1.00
41_I	247_M	0.632	1.00
242_S	246_I	0.629	1.00
234_I	238_C	0.627	1.00
34_N	37_S	0.627	1.00
266_A	271_G	0.627	1.00
70_P	302_K	0.627	1.00
92_L	364_P	0.625	1.00
205_I	208_E	0.624	1.00
136_F	287_L	0.624	1.00
230_G	233_L	0.624	1.00
35_L	39_G	0.623	1.00
211_S	228_T	0.622	1.00
64_S	211_S	0.621	1.00
13_I	16_T	0.621	1.00
192_A	195_S	0.621	1.00
46_W	203_S	0.619	1.00
349_E	352_L	0.618	1.00
115_F	280_F	0.618	1.00
412_W	423_M	0.617	1.00
61_A	65_F	0.615	1.00
74_Y	90_N	0.615	1.00
43_I	240_V	0.613	1.00
411_M	423_M	0.612	1.00
28_V	242_S	0.611	1.00
32_P	243_T	0.609	1.00
112_L	132_V	0.609	1.00
260_S	263_G	0.609	1.00
414_F	421_T	0.608	1.00
20_S	155_T	0.607	1.00
21_G	155_T	0.607	1.00
114_Y	117_P	0.607	1.00
49_T	204_F	0.606	1.00
170_W	174_R	0.606	1.00
134_W	137_V	0.605	1.00
144_P	213_A	0.603	1.00
387_Y	390_V	0.602	1.00
6_D	9_K	0.602	1.00
102_I	353_V	0.600	1.00
422_A	427_N	0.599	1.00
411_M	424_Y	0.597	1.00
323_P	326_G	0.597	1.00
57_S	61_A	0.597	1.00
62_K	66_L	0.594	1.00
143_G	146_M	0.592	1.00
80_C	375_L	0.592	1.00
58_M	390_V	0.592	1.00
336_I	339_L	0.592	1.00
63_M	80_C	0.591	1.00
133_L	335_T	0.591	1.00
73_S	208_E	0.591	1.00
34_N	351_G	0.590	1.00
57_S	207_V	0.590	1.00
410_V	416_T	0.589	1.00
351_G	354_S	0.588	1.00
234_I	237_V	0.587	1.00
420_I	428_Y	0.586	1.00
224_V	228_T	0.586	1.00
280_F	284_A	0.585	1.00
74_Y	86_G	0.585	1.00
114_Y	279_S	0.584	1.00
132_V	290_L	0.584	1.00
377_H	381_G	0.584	1.00
216_V	323_P	0.584	1.00
317_V	320_A	0.583	1.00
313_I	317_V	0.582	1.00
375_L	379_H	0.577	1.00
105_V	109_V	0.577	1.00
360_F	364_P	0.577	1.00
48_V	197_L	0.577	1.00
212_V	296_L	0.577	1.00
297_A	301_A	0.576	1.00
111_Y	282_A	0.576	1.00
28_V	31_L	0.576	1.00
420_I	425_A	0.575	1.00
59_V	394_A	0.574	1.00
146_M	150_V	0.574	1.00
137_V	294_T	0.574	1.00
266_A	274_A	0.572	1.00
43_I	47_L	0.572	1.00
168_F	271_G	0.571	1.00
19_V	23_I	0.571	1.00
203_S	239_Y	0.570	1.00
104_M	286_C	0.570	1.00
46_W	243_T	0.569	1.00
148_T	291_G	0.569	1.00
97_C	293_W	0.567	1.00
49_T	201_L	0.566	1.00
181_A	186_G	0.566	1.00
181_A	184_V	0.565	1.00
391_T	405_S	0.565	1.00
34_N	38_T	0.561	1.00
35_L	200_T	0.560	1.00
147_I	295_L	0.560	1.00
359_I	402_V	0.559	1.00
73_S	212_V	0.558	1.00
92_L	363_V	0.557	1.00
29_F	162_I	0.554	1.00
217_V	224_V	0.554	1.00
168_F	270_L	0.553	1.00
415_V	424_Y	0.553	1.00
6_D	70_P	0.552	1.00
72_G	211_S	0.549	1.00
413_S	428_Y	0.549	1.00
111_Y	263_G	0.549	1.00
373_L	391_T	0.548	1.00
55_G	394_A	0.548	1.00
393_I	397_Y	0.548	1.00
388_L	391_T	0.545	1.00
45_G	193_I	0.545	1.00
414_F	420_I	0.544	1.00
266_A	270_L	0.543	1.00
22_N	209_S	0.543	1.00
115_F	279_S	0.542	1.00
285_G	288_G	0.542	1.00
152_A	156_V	0.539	1.00
182_W	185_S	0.538	1.00
350_F	354_S	0.538	1.00
173_F	249_M	0.537	1.00
220_P	223_N	0.537	1.00
416_T	421_T	0.533	1.00
28_V	162_I	0.532	1.00
104_M	107_I	0.532	1.00
245_A	248_G	0.532	1.00
15_V	213_A	0.531	1.00
398_C	402_V	0.531	1.00
208_E	365_Y	0.530	1.00
250_I	254_A	0.529	1.00
299_Q	323_P	0.529	1.00
126_T	129_C	0.528	1.00
8_H	218_K	0.527	1.00
98_W	330_V	0.526	1.00
329_I	333_L	0.525	1.00
411_M	418_M	0.525	1.00
181_A	185_S	0.525	1.00
107_I	111_Y	0.524	1.00
234_I	241_L	0.524	1.00
411_M	427_N	0.522	1.00
361_T	364_P	0.521	1.00
28_V	32_P	0.520	1.00
261_P	265_A	0.520	1.00
24_M	29_F	0.518	1.00
89_T	364_P	0.518	1.00
217_V	227_A	0.517	1.00
173_F	177_T	0.517	1.00
160_I	163_V	0.517	1.00
10_V	144_P	0.517	1.00
96_A	360_F	0.517	1.00
56_L	208_E	0.517	1.00
77_A	86_G	0.516	1.00
35_L	196_T	0.515	1.00
66_L	375_L	0.515	1.00
277_I	281_C	0.515	1.00
20_S	23_I	0.514	1.00
385_P	389_A	0.514	1.00
397_Y	400_W	0.513	1.00
155_T	158_A	0.512	1.00
193_I	197_L	0.511	1.00
324_V	327_L	0.511	1.00
250_I	264_D	0.510	1.00
30_L	33_A	0.509	1.00
131_V	134_W	0.508	1.00
26_S	104_M	0.507	1.00
144_P	148_T	0.507	1.00
410_V	422_A	0.506	1.00
205_I	357_S	0.506	1.00
266_A	269_A	0.506	1.00
54_L	232_V	0.506	1.00
134_W	328_I	0.506	1.00
102_I	105_V	0.505	1.00
82_G	86_G	0.505	1.00
210_A	224_V	0.504	1.00
397_Y	401_A	0.504	1.00
414_F	429_N	0.502	1.00
222_R	225_P	0.501	1.00
290_L	293_W	0.501	1.00
263_G	267_R	0.500	1.00
161_P	277_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9506	100	0.218	Contact Map
3giaA	1	0.9528	100	0.33	Contact Map
4djkA	2	0.9056	100	0.361	Contact Map
2jlnA	1	0.8966	99.1	0.849	Contact Map
3dh4A	3	0.9393	98.9	0.855	Contact Map
2xq2A	2	0.9416	98.9	0.857	Contact Map
2a65A	2	0.9281	97.7	0.899	Contact Map
4xp4A	1	0.9483	97.6	0.901	Contact Map
4wgvA	2	0.8157	97.6	0.902	Contact Map
4us3A	1	0.8809	97.1	0.909	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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