YGCE - ECOLI - GREMLIN Contacts

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YGCE - Uncharacterized sugar kinase YgcE

UniProt:	P55138	Sequences: MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDNMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13033
Length:	492 (437)
Sequences:	12496 (8542)
Seq/√Len:	408.6

ECOLI - YGCE LSRK LYXK ARAB XYLB FUCK RHAB GLPK
BACSU - GNTK XYLB ARAB YOAC GLPK RHAB
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
159_E	171_R	4.209	1.00
22_D	26_N	3.494	1.00
18_V	60_A	3.395	1.00
151_D	154_S	2.926	1.00
358_K	362_D	2.913	1.00
398_P	441_I	2.861	1.00
33_G	59_F	2.799	1.00
358_K	454_N	2.719	1.00
389_Q	393_D	2.707	1.00
333_M	345_I	2.690	1.00
307_V	344_W	2.689	1.00
150_V	177_V	2.689	1.00
374_H	400_R	2.672	1.00
33_G	63_D	2.661	1.00
39_H	99_P	2.647	1.00
424_P	428_T	2.647	1.00
425_D	428_T	2.622	1.00
31_G	63_D	2.602	1.00
179_M	182_T	2.575	1.00
136_E	176_D	2.569	1.00
385_D	438_D	2.478	1.00
54_W	132_R	2.464	1.00
20_M	64_L	2.416	1.00
92_A	120_A	2.406	1.00
51_D	132_R	2.388	1.00
151_D	158_S	2.357	1.00
164_M	171_R	2.339	1.00
156_A	171_R	2.278	1.00
121_Y	137_F	2.240	1.00
358_K	451_D	2.211	1.00
207_T	212_V	2.178	1.00
19_V	409_S	2.175	1.00
159_E	165_D	2.151	1.00
9_I	57_L	2.150	1.00
4_K	76_V	2.124	1.00
130_T	206_T	2.123	1.00
15_S	32_K	2.062	1.00
188_T	191_A	2.044	1.00
312_N	344_W	2.024	1.00
114_H	118_D	2.015	1.00
443_I	446_N	2.012	1.00
273_T	349_I	2.008	1.00
42_D	45_T	1.978	1.00
63_D	67_Q	1.966	1.00
6_I	417_A	1.936	1.00
403_A	435_R	1.920	1.00
316_T	333_M	1.901	1.00
396_N	447_A	1.898	1.00
341_D	344_W	1.898	1.00
306_C	343_A	1.898	1.00
7_I	61_G	1.897	1.00
36_Q	52_D	1.892	1.00
51_D	95_T	1.869	1.00
377_I	388_M	1.864	1.00
315_M	457_I	1.858	1.00
296_P	299_L	1.851	1.00
7_I	18_V	1.851	1.00
11_G	16_T	1.850	1.00
189_P	199_A	1.833	1.00
134_T	203_V	1.830	1.00
454_N	459_K	1.807	1.00
5_Y	28_V	1.806	1.00
299_L	302_K	1.783	1.00
277_L	349_I	1.769	1.00
204_V	419_G	1.767	1.00
400_R	439_I	1.758	1.00
233_I	269_K	1.753	1.00
178_Q	182_T	1.745	1.00
221_D	431_D	1.699	1.00
94_G	131_H	1.693	1.00
91_K	95_T	1.689	1.00
398_P	439_I	1.682	1.00
393_D	446_N	1.663	1.00
303_K	343_A	1.663	1.00
138_K	178_Q	1.662	1.00
183_V	186_H	1.646	1.00
5_Y	20_M	1.644	1.00
303_K	306_C	1.640	1.00
224_T	374_H	1.638	1.00
113_E	117_P	1.627	1.00
393_D	443_I	1.626	1.00
4_K	74_D	1.614	1.00
447_A	451_D	1.604	1.00
295_S	299_L	1.596	1.00
183_V	204_V	1.596	1.00
111_P	114_H	1.594	1.00
88_A	125_F	1.583	1.00
89_L	173_M	1.560	1.00
275_S	279_D	1.560	1.00
153_K	242_L	1.554	1.00
355_L	453_M	1.532	1.00
110_R	114_H	1.524	1.00
330_R	337_D	1.511	1.00
362_D	459_K	1.504	1.00
460_D	464_H	1.502	1.00
316_T	320_W	1.495	1.00
403_A	437_K	1.495	1.00
6_I	422_L	1.481	1.00
31_G	64_L	1.467	1.00
23_L	422_L	1.458	1.00
31_G	60_A	1.456	1.00
170_P	173_M	1.444	1.00
302_K	306_C	1.442	1.00
54_W	58_C	1.438	1.00
49_P	52_D	1.438	1.00
198_P	201_L	1.435	1.00
445_S	448_K	1.433	1.00
130_T	184_L	1.428	1.00
417_A	423_Y	1.419	1.00
64_L	68_F	1.414	1.00
386_L	390_I	1.395	1.00
65_M	72_K	1.388	1.00
385_D	401_R	1.386	1.00
301_N	305_S	1.382	1.00
77_G	416_T	1.382	1.00
304_A	386_L	1.381	1.00
303_K	342_Y	1.376	1.00
300_L	346_Y	1.371	1.00
20_M	68_F	1.367	1.00
128_Y	132_R	1.367	1.00
9_I	61_G	1.367	1.00
29_C	64_L	1.362	1.00
29_C	67_Q	1.358	1.00
134_T	185_G	1.358	1.00
347_R	351_E	1.358	1.00
39_H	52_D	1.355	1.00
229_L	391_F	1.351	1.00
51_D	55_A	1.341	1.00
385_D	440_F	1.335	1.00
354_A	390_I	1.330	1.00
92_A	121_Y	1.327	1.00
225_A	372_A	1.320	1.00
90_L	123_T	1.316	1.00
186_H	200_G	1.315	1.00
71_N	74_D	1.300	1.00
84_R	208_S	1.299	1.00
314_L	340_M	1.294	1.00
109_T	113_E	1.288	1.00
223_E	373_K	1.287	1.00
240_K	257_P	1.285	1.00
354_A	394_V	1.284	1.00
374_H	398_P	1.282	1.00
227_I	391_F	1.281	1.00
178_Q	184_L	1.280	1.00
354_A	391_F	1.278	1.00
16_T	57_L	1.271	1.00
141_I	155_W	1.266	1.00
336_F	340_M	1.263	1.00
21_Y	27_V	1.257	1.00
401_R	440_F	1.251	1.00
299_L	303_K	1.226	1.00
86_C	100_L	1.226	1.00
388_M	440_F	1.220	1.00
266_G	356_T	1.217	1.00
448_K	452_A	1.217	1.00
396_N	451_D	1.217	1.00
29_C	68_F	1.216	1.00
222_D	240_K	1.215	1.00
207_T	415_N	1.211	1.00
302_K	305_S	1.206	1.00
164_M	174_L	1.206	1.00
183_V	202_P	1.199	1.00
414_I	433_M	1.198	1.00
301_N	385_D	1.194	1.00
316_T	349_I	1.192	1.00
136_E	178_Q	1.188	1.00
16_T	56_S	1.183	1.00
390_I	394_V	1.182	1.00
359_N	459_K	1.182	1.00
118_D	166_K	1.181	1.00
446_N	449_R	1.177	1.00
130_T	138_K	1.176	1.00
221_D	224_T	1.171	1.00
59_F	63_D	1.170	1.00
358_K	395_F	1.170	1.00
9_I	18_V	1.168	1.00
55_A	59_F	1.165	1.00
57_L	129_L	1.165	1.00
47_E	99_P	1.165	1.00
383_N	405_N	1.162	1.00
160_D	165_D	1.155	1.00
94_G	137_F	1.136	1.00
183_V	419_G	1.128	1.00
334_I	461_L	1.117	1.00
123_T	137_F	1.111	1.00
457_I	460_D	1.110	1.00
362_D	366_N	1.108	1.00
5_Y	74_D	1.107	1.00
268_R	273_T	1.101	1.00
113_E	116_N	1.100	1.00
21_Y	413_A	1.098	1.00
110_R	113_E	1.096	1.00
49_P	99_P	1.093	1.00
36_Q	39_H	1.092	1.00
80_L	130_T	1.091	1.00
298_D	301_N	1.091	1.00
53_L	125_F	1.090	1.00
281_L	345_I	1.090	1.00
65_M	68_F	1.082	1.00
301_N	384_S	1.081	1.00
4_K	23_L	1.079	1.00
20_M	70_G	1.074	1.00
164_M	169_I	1.073	1.00
141_I	177_V	1.072	1.00
77_G	420_L	1.070	1.00
141_I	150_V	1.068	1.00
221_D	427_A	1.064	1.00
225_A	237_M	1.064	1.00
50_D	88_A	1.061	1.00
268_R	271_M	1.061	1.00
63_D	66_S	1.057	1.00
31_G	67_Q	1.055	1.00
6_I	420_L	1.055	1.00
376_I	400_R	1.052	1.00
240_K	259_T	1.050	1.00
138_K	184_L	1.041	1.00
131_H	137_F	1.034	1.00
353_V	381_G	1.031	1.00
224_T	376_I	1.030	1.00
114_H	117_P	1.029	1.00
78_I	201_L	1.029	1.00
57_L	61_G	1.028	1.00
361_Y	395_F	1.024	1.00
307_V	311_C	1.020	1.00
423_Y	429_A	1.016	1.00
70_G	74_D	1.009	1.00
273_T	316_T	1.008	1.00
443_I	447_A	1.002	1.00
46_A	104_Q	1.000	1.00
331_G	336_F	0.998	1.00
226_V	378_T	0.994	1.00
355_L	394_V	0.992	1.00
414_I	429_A	0.992	1.00
5_Y	70_G	0.990	1.00
323_N	326_E	0.988	1.00
89_L	122_V	0.987	1.00
77_G	204_V	0.985	1.00
221_D	373_K	0.985	1.00
362_D	454_N	0.982	1.00
366_N	397_L	0.981	1.00
340_M	344_W	0.980	1.00
326_E	329_K	0.977	1.00
150_V	154_S	0.976	1.00
381_G	387_F	0.976	1.00
35_L	56_S	0.976	1.00
436_V	439_I	0.975	1.00
305_S	386_L	0.973	1.00
303_K	346_Y	0.972	1.00
418_V	429_A	0.969	1.00
85_C	146_G	0.965	1.00
6_I	77_G	0.965	1.00
81_G	408_A	0.961	1.00
444_E	447_A	0.960	1.00
316_T	348_S	0.960	1.00
62_H	66_S	0.959	1.00
7_I	20_M	0.957	1.00
37_P	48_H	0.957	1.00
18_V	64_L	0.952	1.00
155_W	179_M	0.951	1.00
358_K	394_V	0.949	1.00
21_Y	410_L	0.937	1.00
396_N	449_R	0.937	1.00
186_H	202_P	0.930	1.00
52_D	55_A	0.928	1.00
204_V	420_L	0.928	1.00
374_H	439_I	0.923	1.00
417_A	422_L	0.920	1.00
135_G	188_T	0.918	1.00
22_D	28_V	0.918	1.00
139_D	144_Y	0.911	1.00
297_E	300_L	0.910	1.00
235_L	361_Y	0.910	1.00
95_T	132_R	0.905	1.00
304_A	307_V	0.898	1.00
347_R	386_L	0.896	1.00
157_W	174_L	0.895	1.00
233_I	357_L	0.894	1.00
127_G	139_D	0.893	1.00
375_V	395_F	0.891	1.00
33_G	60_A	0.890	1.00
97_A	120_A	0.890	1.00
336_F	345_I	0.889	1.00
395_F	398_P	0.887	1.00
79_G	204_V	0.887	1.00
20_M	75_I	0.886	1.00
11_G	129_L	0.882	1.00
76_V	420_L	0.875	1.00
58_C	62_H	0.875	1.00
138_K	176_D	0.873	1.00
80_L	129_L	0.872	1.00
65_M	75_I	0.870	1.00
30_E	406_G	0.868	1.00
7_I	75_I	0.868	1.00
124_S	147_Q	0.867	1.00
87_R	122_V	0.863	1.00
156_A	176_D	0.862	1.00
282_G	342_Y	0.854	1.00
153_K	244_K	0.852	1.00
141_I	179_M	0.846	1.00
76_V	422_L	0.845	1.00
355_L	454_N	0.844	1.00
444_E	449_R	0.844	1.00
144_Y	157_W	0.843	1.00
41_P	45_T	0.842	1.00
333_M	349_I	0.842	1.00
89_L	97_A	0.841	1.00
90_L	94_G	0.836	1.00
418_V	426_Y	0.836	1.00
186_H	199_A	0.834	1.00
307_V	312_N	0.834	1.00
298_D	302_K	0.833	1.00
350_L	390_I	0.829	1.00
310_G	313_G	0.828	1.00
234_A	265_Y	0.827	1.00
277_L	346_Y	0.826	1.00
213_E	378_T	0.823	1.00
158_S	163_V	0.822	1.00
73_E	198_P	0.821	1.00
276_W	279_D	0.821	1.00
189_P	200_G	0.818	1.00
156_A	159_E	0.816	1.00
52_D	56_S	0.815	1.00
304_A	347_R	0.814	1.00
80_L	133_L	0.813	1.00
225_A	375_V	0.813	1.00
84_R	143_N	0.813	1.00
382_S	405_N	0.811	1.00
318_L	321_L	0.810	1.00
444_E	448_K	0.809	1.00
187_I	201_L	0.809	1.00
400_R	436_V	0.809	1.00
91_K	97_A	0.800	1.00
142_A	207_T	0.799	1.00
75_I	201_L	0.799	1.00
237_M	364_M	0.796	1.00
153_K	241_A	0.794	1.00
47_E	107_R	0.793	1.00
178_Q	205_C	0.793	1.00
210_K	234_A	0.792	1.00
33_G	56_S	0.791	1.00
329_K	332_I	0.791	1.00
428_T	432_N	0.791	1.00
34_L	275_S	0.789	1.00
58_C	191_A	0.785	1.00
217_A	378_T	0.783	1.00
40_T	46_A	0.782	1.00
27_V	30_E	0.781	1.00
84_R	263_E	0.780	1.00
72_K	75_I	0.777	1.00
101_I	107_R	0.777	1.00
269_K	353_V	0.775	1.00
354_A	387_F	0.775	1.00
213_E	408_A	0.774	1.00
460_D	463_K	0.773	1.00
313_G	453_M	0.770	1.00
103_W	232_Y	0.768	1.00
139_D	175_F	0.765	1.00
8_G	79_G	0.765	1.00
307_V	310_G	0.764	1.00
452_A	457_I	0.761	1.00
11_G	57_L	0.761	1.00
88_A	100_L	0.758	1.00
377_I	391_F	0.757	1.00
242_L	251_P	0.757	1.00
150_V	155_W	0.757	1.00
305_S	385_D	0.754	1.00
238_N	259_T	0.754	1.00
126_S	206_T	0.751	1.00
139_D	177_V	0.751	1.00
377_I	401_R	0.749	1.00
61_G	65_M	0.749	1.00
91_K	120_A	0.748	1.00
448_K	453_M	0.747	1.00
350_L	384_S	0.747	1.00
113_E	328_Y	0.747	1.00
278_R	297_E	0.745	1.00
90_L	137_F	0.743	1.00
187_I	198_P	0.743	1.00
423_Y	432_N	0.742	1.00
227_I	357_L	0.742	1.00
382_S	388_M	0.742	1.00
227_I	233_I	0.740	1.00
13_S	102_S	0.738	1.00
217_A	226_V	0.738	1.00
315_M	334_I	0.736	1.00
325_W	329_K	0.736	1.00
19_V	27_V	0.734	1.00
94_G	120_A	0.734	1.00
307_V	343_A	0.732	1.00
34_L	278_R	0.730	1.00
275_S	297_E	0.727	1.00
284_S	300_L	0.727	1.00
358_K	459_K	0.723	1.00
359_N	454_N	0.723	1.00
255_S	258_Q	0.714	1.00
277_L	345_I	0.714	1.00
389_Q	443_I	0.714	1.00
21_Y	404_I	0.713	1.00
77_G	202_P	0.713	1.00
151_D	156_A	0.713	1.00
377_I	399_A	0.711	1.00
363_N	367_E	0.710	1.00
50_D	99_P	0.708	1.00
197_F	200_G	0.706	1.00
308_P	311_C	0.706	1.00
16_T	35_L	0.706	1.00
90_L	121_Y	0.705	1.00
35_L	48_H	0.703	1.00
218_G	434_V	0.702	1.00
316_T	352_S	0.701	1.00
141_I	256_I	0.697	1.00
82_S	143_N	0.696	1.00
57_L	60_A	0.695	1.00
301_N	304_A	0.695	1.00
245_D	249_Y	0.695	1.00
51_D	96_P	0.692	1.00
266_G	269_K	0.692	1.00
459_K	463_K	0.690	1.00
441_I	444_E	0.689	1.00
351_E	390_I	0.688	1.00
65_M	70_G	0.688	1.00
6_I	76_V	0.686	1.00
197_F	201_L	0.686	1.00
313_G	351_E	0.685	1.00
375_V	399_A	0.684	1.00
304_A	346_Y	0.684	1.00
128_Y	131_H	0.684	1.00
78_I	187_I	0.683	1.00
373_K	397_L	0.681	1.00
209_D	231_T	0.681	1.00
115_T	167_F	0.681	1.00
305_S	389_Q	0.681	1.00
155_W	258_Q	0.681	1.00
446_N	451_D	0.680	1.00
165_D	170_P	0.680	1.00
274_V	301_N	0.679	1.00
219_L	224_T	0.677	1.00
239_G	243_P	0.674	0.99
55_A	58_C	0.674	0.99
375_V	397_L	0.673	0.99
418_V	425_D	0.672	0.99
163_V	167_F	0.669	0.99
121_Y	173_M	0.668	0.99
317_V	332_I	0.668	0.99
11_G	56_S	0.667	0.99
160_D	166_K	0.667	0.99
165_D	171_R	0.666	0.99
130_T	134_T	0.665	0.99
51_D	128_Y	0.664	0.99
47_E	98_A	0.663	0.99
90_L	128_Y	0.661	0.99
89_L	98_A	0.660	0.99
180_P	206_T	0.660	0.99
187_I	197_F	0.657	0.99
312_N	340_M	0.657	0.99
417_A	421_G	0.657	0.99
313_G	347_R	0.657	0.99
265_Y	269_K	0.656	0.99
184_L	205_C	0.655	0.99
126_S	143_N	0.655	0.99
389_Q	440_F	0.654	0.99
449_R	453_M	0.654	0.99
374_H	397_L	0.654	0.99
398_P	442_P	0.653	0.99
23_L	76_V	0.653	0.99
51_D	99_P	0.652	0.99
401_R	437_K	0.651	0.99
21_Y	409_S	0.651	0.99
448_K	451_D	0.649	0.99
58_C	132_R	0.648	0.99
227_I	375_V	0.646	0.99
199_A	202_P	0.646	0.99
83_I	103_W	0.645	0.99
186_H	189_P	0.645	0.99
433_M	436_V	0.643	0.99
453_M	457_I	0.642	0.99
191_A	200_G	0.640	0.99
311_C	347_R	0.639	0.99
121_Y	131_H	0.637	0.99
323_N	327_P	0.637	0.99
61_G	64_L	0.637	0.99
427_A	431_D	0.636	0.99
372_A	397_L	0.635	0.99
247_V	367_E	0.634	0.99
264_G	360_N	0.634	0.99
414_I	418_V	0.633	0.99
183_V	420_L	0.631	0.99
208_S	211_P	0.628	0.99
94_G	121_Y	0.627	0.99
224_T	373_K	0.626	0.99
388_M	401_R	0.623	0.99
59_F	62_H	0.622	0.99
233_I	391_F	0.622	0.99
312_N	339_S	0.622	0.99
142_A	180_P	0.621	0.99
82_S	125_F	0.618	0.99
301_N	386_L	0.617	0.99
149_P	174_L	0.617	0.99
90_L	131_H	0.614	0.99
120_A	172_H	0.613	0.99
165_D	168_N	0.612	0.99
310_G	344_W	0.612	0.99
396_N	444_E	0.612	0.99
127_G	137_F	0.609	0.99
30_E	67_Q	0.607	0.99
58_C	61_G	0.605	0.99
214_A	236_M	0.605	0.99
347_R	390_I	0.604	0.99
78_I	203_V	0.602	0.99
69_A	72_K	0.601	0.99
54_W	191_A	0.601	0.99
27_V	404_I	0.600	0.99
277_L	281_L	0.599	0.99
90_L	120_A	0.599	0.99
188_T	200_G	0.598	0.99
180_P	207_T	0.597	0.99
311_C	315_M	0.596	0.99
141_I	255_S	0.596	0.99
423_Y	433_M	0.595	0.99
385_D	389_Q	0.595	0.99
382_S	401_R	0.592	0.99
24_E	432_N	0.591	0.99
229_L	377_I	0.591	0.99
235_L	360_N	0.590	0.99
75_I	197_F	0.589	0.99
50_D	100_L	0.588	0.99
297_E	301_N	0.588	0.99
389_Q	392_A	0.587	0.99
119_V	163_V	0.587	0.99
23_L	417_A	0.586	0.99
86_C	102_S	0.584	0.99
123_T	131_H	0.584	0.99
51_D	54_W	0.581	0.98
216_G	407_C	0.580	0.98
351_E	355_L	0.580	0.98
210_K	228_S	0.580	0.98
317_V	462_T	0.577	0.98
318_L	352_S	0.576	0.98
88_A	96_P	0.575	0.98
124_S	143_N	0.575	0.98
307_V	347_R	0.575	0.98
384_S	387_F	0.574	0.98
6_I	23_L	0.574	0.98
274_V	300_L	0.573	0.98
181_G	419_G	0.573	0.98
32_K	406_G	0.571	0.98
418_V	423_Y	0.571	0.98
191_A	197_F	0.570	0.98
415_N	426_Y	0.569	0.98
84_R	146_G	0.569	0.98
263_E	267_I	0.567	0.98
236_M	261_L	0.567	0.98
310_G	347_R	0.566	0.98
96_P	99_P	0.566	0.98
49_P	55_A	0.566	0.98
320_W	333_M	0.565	0.98
239_G	262_Y	0.565	0.98
45_T	101_I	0.564	0.98
418_V	421_G	0.564	0.98
410_L	414_I	0.563	0.98
248_A	264_G	0.562	0.98
304_A	350_L	0.561	0.98
41_P	44_D	0.560	0.98
353_V	387_F	0.560	0.98
142_A	255_S	0.558	0.98
14_Q	17_K	0.558	0.98
86_C	125_F	0.557	0.98
26_N	403_A	0.556	0.98
227_I	235_L	0.556	0.98
308_P	312_N	0.556	0.98
85_C	232_Y	0.556	0.98
321_L	338_S	0.555	0.98
451_D	454_N	0.555	0.98
85_C	103_W	0.554	0.98
48_H	102_S	0.553	0.98
202_P	420_L	0.552	0.98
187_I	196_H	0.550	0.98
228_S	378_T	0.550	0.98
215_L	414_I	0.548	0.98
301_N	350_L	0.548	0.98
136_E	186_H	0.547	0.98
231_T	380_G	0.547	0.98
5_Y	73_E	0.545	0.98
226_V	236_M	0.544	0.98
357_L	391_F	0.544	0.98
153_K	156_A	0.542	0.98
261_L	265_Y	0.541	0.98
147_Q	157_W	0.540	0.98
176_D	182_T	0.540	0.98
83_I	208_S	0.539	0.98
13_S	103_W	0.537	0.97
135_G	190_Q	0.536	0.97
252_I	261_L	0.535	0.97
237_M	372_A	0.535	0.97
228_S	234_A	0.534	0.97
163_V	166_K	0.534	0.97
313_G	457_I	0.533	0.97
146_G	208_S	0.533	0.97
330_R	333_M	0.531	0.97
355_L	358_K	0.531	0.97
46_A	102_S	0.530	0.97
81_G	412_A	0.530	0.97
6_I	423_Y	0.530	0.97
315_M	319_D	0.529	0.97
130_T	205_C	0.529	0.97
85_C	208_S	0.529	0.97
48_H	83_I	0.528	0.97
242_L	260_L	0.528	0.97
275_S	278_R	0.527	0.97
53_L	100_L	0.527	0.97
19_V	410_L	0.526	0.97
169_I	174_L	0.525	0.97
142_A	211_P	0.525	0.97
148_W	167_F	0.524	0.97
215_L	426_Y	0.524	0.97
111_P	115_T	0.524	0.97
392_A	399_A	0.523	0.97
8_G	409_S	0.520	0.97
311_C	344_W	0.519	0.97
283_E	342_Y	0.519	0.97
209_D	380_G	0.519	0.97
228_S	408_A	0.519	0.97
271_M	275_S	0.518	0.97
356_T	359_N	0.518	0.97
266_G	360_N	0.517	0.97
280_M	341_D	0.517	0.97
259_T	426_Y	0.516	0.97
224_T	431_D	0.516	0.97
229_L	381_G	0.515	0.97
129_L	133_L	0.515	0.97
277_L	282_G	0.515	0.97
322_T	326_E	0.515	0.97
265_Y	322_T	0.514	0.97
227_I	377_I	0.514	0.97
5_Y	68_F	0.513	0.97
56_S	59_F	0.512	0.97
68_F	72_K	0.512	0.97
261_L	269_K	0.512	0.97
235_L	357_L	0.512	0.97
315_M	355_L	0.509	0.97
316_T	319_D	0.509	0.97
50_D	125_F	0.508	0.96
181_G	418_V	0.508	0.96
4_K	422_L	0.507	0.96
303_K	307_V	0.507	0.96
115_T	119_V	0.507	0.96
83_I	100_L	0.505	0.96
409_S	412_A	0.505	0.96
313_G	316_T	0.504	0.96
60_A	64_L	0.503	0.96
155_W	255_S	0.503	0.96
260_L	263_E	0.503	0.96
300_L	384_S	0.502	0.96
47_E	101_I	0.502	0.96
317_V	461_L	0.501	0.96
130_T	203_V	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ll3A	2	0.9187	100	0.181	Contact Map
3qdkA	2	0.9593	100	0.2	Contact Map
3ifrA	2	0.9146	100	0.202	Contact Map
3hz6A	1	0.9024	100	0.203	Contact Map
2itmA	2	0.8943	100	0.205	Contact Map
3wxlA	2	0.9167	100	0.222	Contact Map
3ezwA	3	0.9146	100	0.224	Contact Map
3l0qA	2	0.9411	100	0.225	Contact Map
3h3nX	3	0.9146	100	0.227	Contact Map
3g25A	3	0.9106	100	0.23	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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