GREMLIN Database
HRSA - Heat-responsive suppressor HrsA
UniProt: P54745 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13235
Length: 658 (610)
Sequences: 948 (552)
Seq/√Len: 22.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
187_V242_C5.9811.00
532_S540_F5.4331.00
528_T634_S5.1041.00
520_S627_A4.7911.00
489_F495_V4.5281.00
379_A383_A4.4241.00
274_E278_Q4.3301.00
534_M552_W4.3101.00
390_A407_G4.2201.00
213_L278_Q4.2101.00
227_I230_R4.1631.00
241_A280_A4.0961.00
414_L444_G4.0351.00
213_L274_E3.9221.00
29_R162_D3.8271.00
210_G217_V3.7501.00
215_V277_I3.6651.00
367_V404_A3.6381.00
533_T548_G3.6311.00
234_D238_S3.6241.00
188_C219_V3.5561.00
257_N289_T3.5151.00
272_H275_A3.4331.00
40_S43_E3.3751.00
233_A237_N3.2991.00
209_A212_K3.2631.00
111_G118_V3.2571.00
365_L392_L3.1841.00
331_A355_R3.1091.00
91_A129_N3.0461.00
50_Q61_T2.9600.99
278_Q282_T2.9390.99
46_H65_L2.9340.99
580_L637_I2.9070.99
212_K274_E2.8130.99
595_G610_H2.8110.99
185_T238_S2.7460.99
385_A442_T2.7320.99
485_F579_V2.7250.99
53_A58_I2.7150.99
625_G629_V2.5880.99
67_E90_T2.5760.98
268_E272_H2.5520.98
68_V123_L2.5040.98
309_A377_S2.4830.98
501_A504_L2.4800.98
49_T65_L2.4190.98
260_P283_L2.4110.98
422_L436_L2.3800.97
316_F384_L2.3370.97
218_Y235_Q2.3280.97
422_L440_L2.3230.97
529_V638_L2.3210.97
460_I463_S2.2820.97
119_D156_Q2.2300.96
622_G625_G2.2270.96
185_T240_T2.2150.96
279_Q284_K2.2000.96
588_I592_M2.1680.96
520_S585_T2.1490.95
62_E66_E2.1390.95
485_F583_M2.1300.95
241_A262_L2.1230.95
160_T163_E2.0940.95
257_N290_R2.0920.95
574_V638_L2.0830.94
373_Y376_Y2.0660.94
159_T163_E2.0620.94
38_F44_A2.0150.93
204_E207_E1.9440.92
375_A411_A1.9290.92
186_I215_V1.9280.92
488_S582_S1.9110.91
538_R644_H1.9020.91
489_F579_V1.8800.91
539_L639_L1.8750.91
540_F639_L1.8680.90
209_A274_E1.8560.90
415_M441_G1.8490.90
369_V388_F1.8430.90
118_V121_V1.7770.88
532_S639_L1.7590.87
542_E545_I1.7570.87
209_A213_L1.7560.87
535_L552_W1.7460.87
355_R359_G1.7310.87
465_T469_N1.7150.86
546_E549_K1.6950.85
70_R74_L1.6840.85
153_A157_S1.6800.85
60_S63_Q1.6790.85
279_Q282_T1.6670.84
152_R156_Q1.6600.84
592_M622_G1.6520.84
542_E546_E1.6520.84
594_I622_G1.6520.84
500_Y515_Y1.6500.84
632_A635_T1.6490.84
100_V164_L1.6420.83
320_L388_F1.6370.83
440_L444_G1.6280.83
220_E255_R1.6200.83
463_S467_W1.6180.82
485_F521_V1.6120.82
140_T144_T1.6080.82
149_D153_A1.6060.82
375_A387_G1.6020.82
148_D171_K1.5980.82
636_A640_M1.5950.82
302_V305_E1.5910.81
45_I109_W1.5860.81
213_L277_I1.5850.81
402_L406_V1.5660.80
323_A442_T1.5630.80
387_G411_A1.5610.80
462_N466_A1.5540.80
184_P240_T1.5490.80
183_A216_N1.5480.80
154_R170_D1.5440.79
70_R73_S1.5250.78
33_C47_A1.5230.78
35_N102_T1.5100.78
529_V551_T1.5020.77
463_S466_A1.4960.77
512_Y597_S1.4880.77
352_W356_K1.4870.77
50_Q54_A1.4870.77
570_D573_R1.4820.76
576_G641_W1.4600.75
575_I579_V1.4590.75
207_E211_R1.4450.75
626_A629_V1.4330.74
488_S525_S1.4290.74
264_V276_L1.4280.74
36_A47_A1.4280.74
335_S345_N1.4250.74
246_A263_S1.4150.73
45_I65_L1.4080.73
622_G629_V1.4080.73
187_V235_Q1.3980.72
535_L631_A1.3940.72
28_H57_K1.3920.72
166_S170_D1.3890.72
307_K311_L1.3850.71
103_L119_D1.3720.71
44_A103_L1.3690.70
459_W463_S1.3610.70
36_A101_A1.3610.70
136_M147_A1.3480.69
584_V633_I1.3320.68
334_L354_Y1.3290.68
360_G393_A1.3240.68
624_F628_L1.3210.68
539_L644_H1.3160.67
631_A635_T1.3130.67
191_A248_V1.3070.67
536_A639_L1.3040.67
42_E69_Y1.3020.66
188_C246_A1.3010.66
277_I281_L1.2950.66
357_L446_G1.2940.66
629_V633_I1.2940.66
221_K229_G1.2940.66
241_A273_A1.2920.66
483_L514_P1.2900.66
254_E290_R1.2860.65
371_A407_G1.2840.65
38_F47_A1.2810.65
266_V269_P1.2810.65
390_A445_A1.2780.65
488_S560_T1.2660.64
505_G508_A1.2600.64
224_A433_T1.2600.64
82_G119_D1.2530.63
530_T534_M1.2350.62
269_P275_A1.2340.62
580_L629_V1.2310.62
46_H49_T1.2300.62
34_L102_T1.2280.62
588_I626_A1.2270.62
141_A176_P1.2260.62
136_M143_T1.2250.62
237_N240_T1.2240.62
43_E46_H1.2220.61
206_L217_V1.2170.61
140_T225_N1.2100.61
528_T578_F1.2070.60
273_A277_I1.2030.60
535_L635_T1.2020.60
269_P272_H1.1990.60
415_M418_V1.1990.60
379_A416_R1.1980.60
336_Q339_G1.1980.60
79_L136_M1.1970.60
260_P287_D1.1960.60
363_G392_L1.1950.60
484_G623_W1.1860.59
481_A587_A1.1850.59
504_L515_Y1.1780.59
456_P460_I1.1780.59
52_L64_F1.1770.58
69_Y73_S1.1760.58
63_Q66_E1.1760.58
31_A55_L1.1750.58
49_T68_V1.1720.58
578_F634_S1.1660.58
377_S428_F1.1630.58
328_L362_L1.1600.57
388_F392_L1.1570.57
336_Q347_E1.1520.57
147_A167_A1.1520.57
78_A111_G1.1480.57
404_A475_N1.1450.56
584_V629_V1.1390.56
51_R54_A1.1350.56
481_A484_G1.1320.55
373_Y458_A1.1300.55
519_A558_G1.1200.55
418_V422_L1.1170.54
67_E88_G1.1140.54
300_K304_T1.1120.54
241_A277_I1.1100.54
35_N104_S1.1100.54
557_A604_F1.1070.54
28_H95_E1.1050.54
112_V117_A1.1050.54
264_V268_E1.1010.53
39_T43_E1.1000.53
522_K558_G1.0990.53
312_S376_Y1.0970.53
66_E73_S1.0950.53
531_A631_A1.0940.53
336_Q341_Q1.0900.53
500_Y507_M1.0890.52
36_A103_L1.0860.52
215_V281_L1.0840.52
89_K132_G1.0830.52
53_A61_T1.0830.52
208_K543_F1.0810.52
52_L68_V1.0800.52
78_A112_V1.0730.51
353_M451_F1.0720.51
342_D347_E1.0710.51
137_Q228_E1.0670.51
399_S403_G1.0640.51
136_M146_L1.0630.51
513_G590_G1.0620.51
59_S94_K1.0610.51
43_E186_I1.0570.50
487_C519_A1.0540.50
224_A381_K1.0540.50
149_D152_R1.0480.50
162_D166_S1.0450.49
393_A454_G1.0450.49
188_C217_V1.0420.49
609_L623_W1.0400.49
335_S351_L1.0350.49
556_L624_F1.0350.49
439_V443_L1.0350.49
487_C558_G1.0310.49
96_A127_P1.0310.49
67_E70_R1.0290.48
305_E309_A1.0260.48
541_K544_E1.0250.48
588_I629_V1.0250.48
483_L634_S1.0170.48
224_A434_F1.0160.47
97_A101_A1.0160.47
280_A284_K1.0140.47
577_S637_I1.0120.47
527_F631_A1.0120.47
39_T160_T1.0100.47
185_T216_N1.0070.47
163_E167_A1.0030.47
42_E50_Q1.0010.46
123_L131_A1.0010.46
606_L620_A0.9980.46
186_I281_L0.9970.46
375_A383_A0.9950.46
577_S641_W0.9880.46
137_Q140_T0.9870.46
38_F103_L0.9850.45
373_Y384_L0.9840.45
406_V410_I0.9840.45
361_L389_A0.9800.45
587_A591_A0.9780.45
275_A279_Q0.9770.45
234_D237_N0.9760.45
606_L609_L0.9750.45
591_A626_A0.9740.45
302_V413_Y0.9710.44
487_C522_K0.9670.44
330_V333_L0.9620.44
500_Y523_M0.9610.44
530_T552_W0.9610.44
637_I641_W0.9600.44
587_A590_G0.9600.44
404_A511_V0.9600.44
208_K211_R0.9570.43
504_L511_V0.9570.43
303_K330_V0.9550.43
405_V505_G0.9550.43
334_L350_W0.9550.43
393_A450_L0.9550.43
70_R111_G0.9530.43
443_L447_S0.9510.43
81_E115_P0.9500.43
341_Q347_E0.9480.43
424_L432_L0.9470.43
353_M357_L0.9440.43
461_N498_A0.9430.43
33_C51_R0.9420.42
185_T217_V0.9410.42
150_E154_R0.9370.42
30_D55_L0.9350.42
189_V253_S0.9330.42
85_V143_T0.9320.42
184_P281_L0.9310.42
339_G342_D0.9300.42
503_C518_F0.9270.41
209_A278_Q0.9260.41
519_A522_K0.9240.41
589_V594_I0.9230.41
32_L66_E0.9210.41
149_D208_K0.9210.41
196_I430_G0.9150.41
189_V222_Q0.9140.41
63_Q91_A0.9120.40
337_I341_Q0.9060.40
371_A375_A0.9010.40
248_V433_T0.8980.40
37_R43_E0.8930.39
424_L436_L0.8890.39
322_V547_T0.8860.39
467_W470_G0.8850.39
32_L203_A0.8840.39
516_A523_M0.8830.39
187_V231_L0.8830.39
88_G132_G0.8810.38
186_I210_G0.8780.38
318_V432_L0.8780.38
65_L109_W0.8770.38
203_A207_E0.8770.38
167_A171_K0.8740.38
47_A103_L0.8740.38
132_G138_L0.8720.38
322_V549_K0.8710.38
103_L121_V0.8640.37
523_M558_G0.8640.37
429_N432_L0.8640.37
314_I321_I0.8600.37
244_F284_K0.8600.37
58_I61_T0.8580.37
162_D637_I0.8570.37
373_Y419_K0.8560.37
507_M515_Y0.8540.37
504_L508_A0.8540.37
181_S297_Q0.8530.37
339_G343_L0.8530.37
150_E153_A0.8530.37
491_L560_T0.8520.37
49_T69_Y0.8520.37
480_G484_G0.8500.36
39_T157_S0.8500.36
476_A513_G0.8490.36
335_S342_D0.8490.36
209_A273_A0.8490.36
513_G589_V0.8480.36
183_A238_S0.8470.36
109_W271_R0.8450.36
30_D178_A0.8440.36
485_F489_F0.8430.36
232_T235_Q0.8400.36
464_L482_I0.8380.36
477_L591_A0.8370.36
181_S261_A0.8320.35
328_L359_G0.8300.35
448_L452_V0.8280.35
414_L417_W0.8260.35
38_F101_A0.8250.35
42_E46_H0.8220.35
191_A246_A0.8200.35
48_L99_A0.8200.35
384_L387_G0.8190.35
484_G520_S0.8180.34
78_A143_T0.8180.34
471_L475_N0.8160.34
145_R171_K0.8150.34
78_A102_T0.8140.34
500_Y589_V0.8140.34
126_I130_E0.8100.34
208_K212_K0.8090.34
133_T143_T0.8080.34
481_A583_M0.8050.34
63_Q92_A0.8050.34
58_I92_A0.8050.34
36_A48_L0.8000.33
340_L347_E0.8000.33
189_V371_A0.7990.33
337_I347_E0.7990.33
42_E110_E0.7960.33
531_A534_M0.7950.33
570_D642_R0.7930.33
483_L518_F0.7900.33
46_H50_Q0.7890.33
52_L97_A0.7890.33
185_T235_Q0.7820.32
121_V222_Q0.7810.32
503_C509_N0.7790.32
487_C523_M0.7780.32
333_L603_I0.7770.32
254_E257_N0.7760.32
339_G347_E0.7760.32
123_L222_Q0.7760.32
335_S344_F0.7740.32
477_L624_F0.7730.32
525_S582_S0.7730.32
85_V102_T0.7720.32
85_V147_A0.7720.32
141_A414_L0.7720.32
131_A134_T0.7710.32
311_L501_A0.7710.32
287_D579_V0.7700.32
92_A274_E0.7700.32
531_A635_T0.7700.32
444_G448_L0.7700.32
104_S157_S0.7690.31
524_V585_T0.7680.31
360_G450_L0.7670.31
457_V498_A0.7660.31
186_I217_V0.7650.31
456_P459_W0.7620.31
162_D234_D0.7610.31
241_A284_K0.7580.31
516_A522_K0.7570.31
585_T589_V0.7570.31
461_N551_T0.7570.31
268_E279_Q0.7560.31
338_F347_E0.7560.31
187_V511_V0.7560.31
217_V277_I0.7550.31
640_M644_H0.7510.30
588_I622_G0.7500.30
512_Y595_G0.7500.30
43_E47_A0.7500.30
129_N132_G0.7490.30
186_I274_E0.7480.30
42_E73_S0.7470.30
521_V585_T0.7470.30
365_L388_F0.7470.30
34_L161_P0.7460.30
410_I414_L0.7460.30
342_D345_N0.7450.30
110_E118_V0.7440.30
65_L69_Y0.7430.30
81_E152_R0.7430.30
491_L585_T0.7430.30
348_N386_P0.7420.30
172_G176_P0.7420.30
473_G476_A0.7420.30
460_I485_F0.7410.30
336_Q342_D0.7410.30
57_K95_E0.7390.30
485_F582_S0.7380.30
222_Q253_S0.7380.30
67_E143_T0.7370.30
536_A539_L0.7320.29
596_L623_W0.7310.29
46_H68_V0.7310.29
88_G222_Q0.7300.29
527_F556_L0.7300.29
596_L609_L0.7300.29
68_V121_V0.7290.29
33_C54_A0.7280.29
62_E541_K0.7280.29
153_A175_Q0.7270.29
481_A633_I0.7270.29
123_L140_T0.7270.29
366_M404_A0.7260.29
301_S305_E0.7240.29
48_L123_L0.7220.29
452_V456_P0.7210.29
335_S347_E0.7190.29
579_V582_S0.7170.29
434_F439_V0.7170.29
332_V598_T0.7160.28
335_S404_A0.7160.28
46_H69_Y0.7150.28
507_M510_G0.7150.28
314_I504_L0.7150.28
543_F546_E0.7140.28
161_P164_L0.7140.28
439_V518_F0.7120.28
334_L339_G0.7110.28
81_E143_T0.7100.28
205_Y209_A0.7090.28
241_A283_L0.7090.28
28_H460_I0.7060.28
101_A131_A0.7050.28
46_H237_N0.7040.28
456_P566_M0.7040.28
64_F68_V0.7030.28
422_L433_T0.7020.28
373_Y468_L0.7010.28
170_D177_S0.7010.28
372_A388_F0.7010.28
310_L409_L0.7000.28
187_V218_Y0.7000.28
66_E234_D0.7000.28
173_G177_S0.6990.28
414_L445_A0.6980.27
460_I553_L0.6970.27
312_S316_F0.6970.27
273_A281_L0.6940.27
309_A378_L0.6940.27
432_L437_Y0.6930.27
101_A107_L0.6930.27
302_V306_L0.6930.27
523_M599_P0.6930.27
332_V558_G0.6920.27
218_Y242_C0.6920.27
344_F347_E0.6920.27
515_Y518_F0.6920.27
343_L347_E0.6910.27
66_E70_R0.6910.27
126_I131_A0.6900.27
470_G474_S0.6900.27
62_E632_A0.6890.27
151_I168_L0.6880.27
244_F253_S0.6860.27
68_V109_W0.6860.27
222_Q244_F0.6850.27
89_K138_L0.6850.27
365_L389_A0.6840.27
418_V424_L0.6830.27
98_F127_P0.6830.27
224_A399_S0.6810.27
531_A535_L0.6800.26
321_I598_T0.6800.26
30_D257_N0.6800.26
26_L140_T0.6800.26
210_G488_S0.6750.26
430_G530_T0.6740.26
457_V460_I0.6730.26
231_L236_L0.6720.26
448_L457_V0.6720.26
500_Y504_L0.6710.26
378_L413_Y0.6690.26
57_K97_A0.6680.26
107_L121_V0.6680.26
186_I280_A0.6670.26
298_P301_S0.6650.26
188_C215_V0.6650.26
336_Q348_N0.6640.26
557_A598_T0.6620.26
588_I591_A0.6620.26
78_A118_V0.6620.26
501_A515_Y0.6610.25
472_S591_A0.6600.25
477_L481_A0.6590.25
466_A470_G0.6590.25
78_A85_V0.6590.25
58_I94_K0.6590.25
216_N238_S0.6580.25
501_A554_L0.6570.25
489_F521_V0.6550.25
189_V252_E0.6550.25
26_L193_P0.6540.25
471_L477_L0.6520.25
506_A528_T0.6520.25
209_A503_C0.6500.25
159_T295_D0.6500.25
516_A519_A0.6470.25
332_V522_K0.6470.25
123_L129_N0.6460.25
522_K586_G0.6460.25
279_Q322_V0.6450.25
317_A321_I0.6450.25
352_W355_R0.6440.25
507_M511_V0.6440.25
461_N529_V0.6440.25
177_S181_S0.6420.25
272_H279_Q0.6420.25
395_N418_V0.6410.24
519_A523_M0.6410.24
366_M369_V0.6410.24
173_G176_P0.6400.24
551_T638_L0.6390.24
253_S288_E0.6380.24
362_L510_G0.6380.24
130_E477_L0.6370.24
150_E156_Q0.6360.24
460_I467_W0.6360.24
418_V441_G0.6360.24
340_L584_V0.6350.24
306_L495_V0.6350.24
341_Q388_F0.6330.24
158_A330_V0.6330.24
470_G473_G0.6320.24
41_R110_E0.6320.24
366_M384_L0.6320.24
352_W507_M0.6310.24
182_N294_Q0.6300.24
52_L98_F0.6290.24
533_T635_T0.6290.24
387_G391_G0.6290.24
506_A634_S0.6280.24
337_I343_L0.6280.24
544_E560_T0.6280.24
213_L273_A0.6280.24
595_G626_A0.6270.24
137_Q225_N0.6270.24
26_L218_Y0.6270.24
96_A134_T0.6260.24
123_L627_A0.6260.24
542_E584_V0.6260.24
32_L165_L0.6260.24
54_A163_E0.6260.24
469_N473_G0.6250.24
40_S50_Q0.6250.24
544_E548_G0.6240.24
294_Q297_Q0.6240.24
62_E298_P0.6230.24
254_E288_E0.6230.24
521_V579_V0.6230.24
149_D167_A0.6230.24
233_A294_Q0.6230.24
268_E273_A0.6220.24
64_F246_A0.6200.23
210_G219_V0.6200.23
23_L27_T0.6190.23
414_L518_F0.6190.23
205_Y208_K0.6190.23
29_R157_S0.6170.23
182_N238_S0.6160.23
306_L572_L0.6150.23
505_G511_V0.6150.23
119_D153_A0.6140.23
107_L292_V0.6130.23
579_V625_G0.6130.23
186_I277_I0.6130.23
340_L343_L0.6130.23
540_F566_M0.6100.23
385_A506_A0.6100.23
47_A101_A0.6080.23
449_M532_S0.6080.23
519_A604_F0.6070.23
105_E157_S0.6060.23
179_S213_L0.6050.23
230_R252_E0.6040.23
247_E380_D0.6040.23
393_A554_L0.6040.23
365_L518_F0.6040.23
371_A390_A0.6030.23
273_A280_A0.6030.23
39_T181_S0.6030.23
365_L385_A0.6020.23
161_P173_G0.6020.23
609_L620_A0.6020.23
351_L596_L0.6020.23
321_I332_V0.6010.22
330_V640_M0.6010.22
377_S639_L0.6000.22
307_K362_L0.6000.22
207_E273_A0.6000.22
334_L342_D0.6000.22
26_L246_A0.6000.22
49_T58_I0.6000.22
68_V207_E0.5990.22
216_N242_C0.5980.22
389_A605_S0.5980.22
512_Y596_L0.5980.22
322_V336_Q0.5970.22
206_L544_E0.5960.22
81_E149_D0.5950.22
303_K308_Q0.5950.22
535_L639_L0.5930.22
92_A209_A0.5930.22
237_N466_A0.5920.22
577_S634_S0.5920.22
189_V246_A0.5920.22
467_W482_I0.5920.22
79_L405_V0.5920.22
167_A172_G0.5910.22
376_Y495_V0.5910.22
384_L454_G0.5900.22
150_E212_K0.5890.22
417_W489_F0.5880.22
523_M604_F0.5870.22
350_W354_Y0.5860.22
333_L461_N0.5860.22
90_T143_T0.5860.22
336_Q340_L0.5850.22
398_G590_G0.5850.22
204_E399_S0.5850.22
448_L476_A0.5840.22
48_L85_V0.5840.22
366_M589_V0.5830.22
151_I167_A0.5820.22
317_A320_L0.5820.22
372_A626_A0.5820.22
578_F582_S0.5810.22
182_N580_L0.5810.22
516_A558_G0.5810.22
52_L78_A0.5810.22
149_D212_K0.5810.22
97_A103_L0.5800.21
523_M586_G0.5800.21
144_T280_A0.5790.21
577_S583_M0.5790.21
428_F557_A0.5780.21
263_S300_K0.5780.21
205_Y628_L0.5780.21
334_L347_E0.5770.21
215_V460_I0.5770.21
500_Y522_K0.5770.21
58_I137_Q0.5770.21
30_D37_R0.5770.21
31_A101_A0.5770.21
31_A52_L0.5760.21
171_K174_T0.5760.21
207_E210_G0.5760.21
448_L484_G0.5750.21
203_A609_L0.5750.21
383_A451_F0.5720.21
469_N479_L0.5720.21
138_L171_K0.5720.21
30_D621_I0.5720.21
511_V514_P0.5720.21
430_G557_A0.5710.21
99_A140_T0.5710.21
119_D152_R0.5710.21
262_L278_Q0.5700.21
365_L514_P0.5690.21
222_Q248_V0.5680.21
381_K433_T0.5680.21
212_K290_R0.5680.21
140_T434_F0.5670.21
398_G458_A0.5670.21
484_G521_V0.5660.21
326_T536_A0.5650.21
399_S454_G0.5640.21
314_I568_I0.5630.21
205_Y271_R0.5630.21
280_A540_F0.5620.21
337_I340_L0.5620.21
392_L396_M0.5620.21
207_E217_V0.5610.21
410_I495_V0.5600.21
59_S95_E0.5600.21
453_V553_L0.5600.21
482_I542_E0.5590.21
595_G611_D0.5590.21
298_P636_A0.5590.21
611_D622_G0.5580.20
336_Q388_F0.5580.20
301_S304_T0.5570.20
249_A308_Q0.5560.20
469_N511_V0.5560.20
213_L281_L0.5550.20
471_L482_I0.5540.20
53_A62_E0.5540.20
536_A643_R0.5540.20
112_V121_V0.5520.20
623_W627_A0.5520.20
353_M447_S0.5520.20
189_V244_F0.5510.20
185_T234_D0.5500.20
64_F133_T0.5500.20
63_Q67_E0.5500.20
340_L404_A0.5490.20
434_F506_A0.5480.20
317_A362_L0.5470.20
154_R157_S0.5470.20
386_P442_T0.5460.20
166_S169_D0.5460.20
70_R167_A0.5460.20
346_E359_G0.5450.20
402_L491_L0.5450.20
369_V596_L0.5440.20
230_R458_A0.5440.20
396_M579_V0.5430.20
452_V455_E0.5420.20
338_F351_L0.5420.20
98_F138_L0.5420.20
210_G277_I0.5420.20
586_G598_T0.5410.20
246_A264_V0.5410.20
233_A636_A0.5410.20
56_G206_L0.5410.20
425_S428_F0.5390.20
95_E448_L0.5390.20
233_A295_D0.5390.20
593_N635_T0.5390.20
102_T164_L0.5390.20
123_L133_T0.5390.20
405_V439_V0.5390.20
505_G509_N0.5390.20
330_V354_Y0.5380.20
139_L158_A0.5380.20
194_A332_V0.5370.20
328_L355_R0.5370.20
214_G629_V0.5360.20
52_L101_A0.5360.20
393_A411_A0.5350.19
357_L447_S0.5350.19
457_V463_S0.5350.19
309_A491_L0.5340.19
580_L591_A0.5330.19
137_Q252_E0.5320.19
337_I365_L0.5320.19
95_E295_D0.5320.19
46_H61_T0.5310.19
506_A569_E0.5310.19
96_A129_N0.5310.19
321_I324_G0.5310.19
372_A444_G0.5310.19
558_G600_G0.5310.19
187_V476_A0.5300.19
102_T156_Q0.5300.19
246_A276_L0.5300.19
100_V138_L0.5290.19
408_G412_G0.5280.19
63_Q90_T0.5280.19
50_Q295_D0.5280.19
334_L337_I0.5280.19
465_T472_S0.5270.19
37_R104_S0.5270.19
506_A511_V0.5260.19
173_G178_A0.5260.19
78_A456_P0.5260.19
37_R105_E0.5260.19
210_G550_S0.5260.19
222_Q252_E0.5250.19
295_D443_L0.5250.19
311_L390_A0.5240.19
341_Q404_A0.5230.19
161_P211_R0.5230.19
405_V485_F0.5220.19
235_Q238_S0.5220.19
351_L623_W0.5220.19
171_K175_Q0.5210.19
433_T439_V0.5210.19
154_R440_L0.5210.19
295_D299_V0.5190.19
69_Y191_A0.5190.19
296_T531_A0.5190.19
59_S63_Q0.5180.19
309_A413_Y0.5170.19
233_A626_A0.5160.19
112_V115_P0.5160.19
594_I611_D0.5160.19
45_I279_Q0.5160.19
62_E182_N0.5160.19
210_G560_T0.5150.19
426_S636_A0.5150.19
63_Q471_L0.5150.19
145_R151_I0.5150.19
332_V430_G0.5150.19
268_E373_Y0.5140.19
262_L284_K0.5140.19
30_D39_T0.5130.19
365_L405_V0.5130.19
280_A480_G0.5130.19
262_L414_L0.5130.19
446_G449_M0.5130.19
316_F382_P0.5120.19
149_D169_D0.5120.19
398_G456_P0.5120.19
29_R161_P0.5120.19
174_T535_L0.5120.19
472_S597_S0.5110.18
367_V514_P0.5110.18
314_I351_L0.5110.18
193_P381_K0.5090.18
287_D431_F0.5090.18
253_S263_S0.5090.18
354_Y537_P0.5090.18
464_L467_W0.5090.18
43_E150_E0.5090.18
250_I266_V0.5080.18
39_T233_A0.5080.18
29_R70_R0.5070.18
117_A310_L0.5070.18
298_P582_S0.5070.18
96_A156_Q0.5070.18
418_V436_L0.5060.18
210_G213_L0.5060.18
327_V626_A0.5060.18
578_F637_I0.5060.18
540_F544_E0.5060.18
589_V597_S0.5060.18
166_S633_I0.5060.18
583_M587_A0.5060.18
293_Q297_Q0.5060.18
519_A525_S0.5050.18
76_P387_G0.5050.18
359_G489_F0.5050.18
250_I253_S0.5050.18
365_L577_S0.5040.18
80_G399_S0.5040.18
226_G394_A0.5040.18
31_A97_A0.5040.18
42_E478_L0.5030.18
581_G630_G0.5030.18
211_R217_V0.5030.18
60_S535_L0.5020.18
350_W443_L0.5020.18
474_S478_L0.5010.18
265_P271_R0.5010.18
240_T470_G0.5010.18
213_L282_T0.5010.18
529_V604_F0.5000.18
167_A610_H0.5000.18
182_N237_N0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2r48A 1 0.1596 100 0.847 Contact Map
3qnqA 2 0.5517 100 0.86 Contact Map
1a6jA 4 0.2356 100 0.865 Contact Map
2a0jA 1 0.2219 100 0.865 Contact Map
3urrA 2 0.231 100 0.867 Contact Map
1a3aA 2 0.2173 100 0.871 Contact Map
2oq3A 1 0.2188 100 0.872 Contact Map
3oxpA 2 0.2204 100 0.876 Contact Map
3bjvA 2 0.2295 100 0.876 Contact Map
2r4qA 1 0.155 100 0.877 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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