GREMLIN Database
YDBH - Uncharacterized protein YdbH
UniProt: P52645 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13180
Length: 879 (854)
Sequences: 197 (153)
Seq/√Len: 5.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
461_S496_V4.8870.97
852_D855_Q4.8270.97
669_N694_D4.7880.97
127_I422_L3.7220.87
811_L838_E3.6850.87
702_M707_M3.4710.83
141_Q214_L3.4450.83
400_R420_D3.3980.82
794_Y833_L3.3430.80
464_T494_V3.2860.79
698_G738_G3.2400.78
352_S583_V3.2060.77
718_N741_S3.0500.74
785_A788_A3.0190.73
717_L720_L3.0130.73
212_A702_M2.9750.72
254_I325_N2.9430.71
99_L102_L2.9210.70
661_V832_N2.9130.70
76_N90_G2.8590.68
52_I55_K2.8330.68
594_G698_G2.7940.67
330_L692_S2.7760.66
698_G820_G2.6680.63
334_G386_P2.6530.62
835_Y839_E2.6320.62
315_N591_L2.6200.61
725_L729_V2.5920.60
741_S763_S2.5720.60
169_K755_V2.5060.58
14_L508_L2.4730.57
596_L838_E2.4690.56
143_K841_I2.4670.56
38_L758_G2.4530.56
182_A392_V2.4470.56
17_L581_P2.4440.56
717_L859_E2.4310.55
62_L755_V2.4060.54
15_I283_V2.3800.54
34_A680_W2.3350.52
829_G856_A2.3320.52
726_V804_I2.3210.52
610_F706_R2.2700.50
776_D793_R2.2690.50
253_Q397_V2.2650.50
590_N693_V2.2280.48
493_I532_V2.2220.48
631_N662_I2.2200.48
662_I755_V2.2090.48
180_V700_V2.2060.48
594_G810_G2.1950.47
792_L847_S2.1930.47
587_W641_F2.1870.47
360_L390_V2.1720.47
34_A189_V2.1640.46
594_G745_P2.1570.46
698_G758_G2.1540.46
698_G742_G2.1530.46
734_F740_F2.1370.45
289_G790_N2.1340.45
670_I832_N2.1300.45
68_D238_V2.1230.45
453_A741_S2.1160.45
321_L341_L2.0890.44
742_G820_G2.0810.44
716_R760_L2.0790.44
191_L742_G2.0770.44
766_M797_I2.0490.43
307_A375_I2.0300.42
698_G745_P1.9920.41
9_L343_L1.9810.40
398_D620_G1.9770.40
738_G834_N1.9680.40
99_L581_P1.9630.40
420_D423_A1.9560.40
421_G614_G1.9530.40
792_L834_N1.9420.39
395_R425_D1.9410.39
362_F704_Q1.9400.39
325_N701_L1.9380.39
491_K862_A1.9360.39
16_I144_L1.9250.39
758_G810_G1.9170.38
62_L700_V1.9120.38
530_F639_F1.8930.38
629_Q814_M1.8900.38
425_D695_V1.8740.37
21_T255_T1.8730.37
744_L758_G1.8620.37
180_V212_A1.8570.37
792_L820_G1.8480.36
335_E370_S1.8470.36
74_I127_I1.8470.36
299_L312_A1.8450.36
213_T241_R1.8440.36
575_S652_G1.8300.36
437_Y504_F1.8190.35
580_Q628_N1.8140.35
9_L814_M1.8140.35
662_I667_A1.8120.35
525_P576_L1.8060.35
575_S596_L1.8040.35
259_L550_E1.8010.35
623_A633_V1.7810.34
44_I148_L1.7780.34
277_G334_G1.7770.34
806_L837_H1.7690.34
133_I804_I1.7610.34
364_P420_D1.7570.34
121_M707_M1.7520.33
229_W386_P1.7440.33
351_L585_P1.7380.33
568_N838_E1.7270.33
161_K700_V1.7260.33
92_V191_L1.7200.32
509_S823_R1.7180.32
312_A636_V1.7150.32
77_A110_A1.7150.32
738_G792_L1.7040.32
620_G804_I1.6950.32
630_V690_D1.6950.32
556_V639_F1.6930.32
806_L851_G1.6920.32
740_F755_V1.6820.31
621_G797_I1.6780.31
248_L530_F1.6750.31
738_G742_G1.6620.31
386_P421_G1.6610.31
225_A623_A1.6590.31
648_L742_G1.6590.31
795_M835_Y1.6570.31
157_Y332_L1.6540.31
465_L795_M1.6490.30
234_G277_G1.6490.30
739_A774_T1.6480.30
12_L165_Q1.6480.30
808_N857_W1.6420.30
164_F267_S1.6390.30
23_L600_V1.6360.30
323_M751_E1.6290.30
567_G576_L1.6270.30
198_P504_F1.6250.30
463_I626_P1.6150.29
696_L848_L1.6150.29
711_D829_G1.6120.29
810_G840_N1.6060.29
237_I568_N1.6020.29
140_W774_T1.6000.29
596_L663_N1.5860.29
322_S326_S1.5850.29
193_G833_L1.5840.29
334_G632_G1.5810.29
616_G764_G1.5790.28
71_L189_V1.5780.28
269_P784_T1.5730.28
789_I804_I1.5580.28
66_V838_E1.5570.28
234_G386_P1.5520.28
273_F283_V1.5470.28
739_A819_T1.5450.28
287_Q836_H1.5440.28
90_G130_D1.5400.27
161_K253_Q1.5390.27
79_L805_N1.5380.27
198_P575_S1.5370.27
155_L323_M1.5360.27
698_G792_L1.5320.27
670_I693_V1.5290.27
242_D717_L1.5270.27
464_T856_A1.5230.27
34_A630_V1.5190.27
72_A301_V1.5140.27
317_G368_L1.5120.27
782_N848_L1.5080.27
74_I695_V1.5050.27
352_S392_V1.5040.26
94_L97_A1.4990.26
573_K804_I1.4990.26
56_G544_G1.4960.26
366_A550_E1.4940.26
77_A755_V1.4910.26
79_L360_L1.4910.26
61_D650_T1.4810.26
369_R413_G1.4800.26
396_G421_G1.4780.26
9_L18_V1.4760.26
368_L389_G1.4700.26
65_L279_L1.4680.26
417_L668_K1.4590.25
483_E697_G1.4570.25
597_Y636_V1.4540.25
722_S740_F1.4480.25
355_L861_N1.4470.25
618_L770_L1.4460.25
589_M755_V1.4450.25
574_Q835_Y1.4410.25
52_I802_T1.4370.25
114_T255_T1.4370.25
251_P399_G1.4360.25
850_F854_L1.4350.25
259_L461_S1.4330.25
351_L659_A1.4260.25
134_F760_L1.4240.24
647_H677_R1.4200.24
335_E493_I1.4150.24
536_D855_Q1.4150.24
395_R494_V1.4120.24
740_F797_I1.4120.24
656_L771_D1.4090.24
134_F257_Q1.4000.24
227_L669_N1.4000.24
628_N721_S1.3980.24
16_I244_G1.3920.24
809_L857_W1.3880.24
334_G421_G1.3870.24
47_D804_I1.3840.24
430_A778_V1.3830.23
430_A841_I1.3790.23
64_Y77_A1.3780.23
757_D779_V1.3780.23
219_E233_S1.3770.23
264_G277_G1.3700.23
115_L475_L1.3700.23
270_Y345_A1.3690.23
427_L760_L1.3610.23
768_L841_I1.3600.23
23_L148_L1.3570.23
452_V465_L1.3570.23
426_F458_W1.3560.23
594_G820_G1.3560.23
352_S755_V1.3520.23
210_A352_S1.3480.23
531_S755_V1.3440.23
795_M816_A1.3430.23
199_L809_L1.3390.22
258_Q325_N1.3350.22
368_L441_G1.3350.22
364_P400_R1.3340.22
726_V830_T1.3340.22
755_V810_G1.3340.22
420_D602_F1.3300.22
426_F602_F1.3280.22
565_L839_E1.3270.22
92_V434_Q1.3250.22
626_P747_W1.3240.22
635_F654_V1.3220.22
768_L837_H1.3200.22
259_L496_V1.3200.22
661_V670_I1.3190.22
129_I254_I1.3120.22
62_L480_M1.3110.22
64_Y743_A1.3110.22
600_V729_V1.3070.22
392_V491_K1.3060.22
162_V323_M1.3060.22
259_L665_V1.3030.22
806_L835_Y1.3020.22
87_L780_K1.3010.22
201_P697_G1.2930.21
849_R852_D1.2870.21
717_L757_D1.2860.21
236_L254_I1.2830.21
760_L802_T1.2830.21
225_A232_N1.2710.21
334_G567_G1.2710.21
194_E279_L1.2700.21
399_G708_P1.2690.21
74_I741_S1.2680.21
127_I652_G1.2640.21
355_L405_L1.2640.21
97_A169_K1.2620.21
316_F661_V1.2560.21
264_G386_P1.2540.21
758_G848_L1.2530.21
134_F463_I1.2520.21
188_P775_A1.2520.21
746_L805_N1.2500.20
698_G810_G1.2460.20
76_N755_V1.2360.20
657_R673_D1.2360.20
99_L812_L1.2350.20
594_G844_L1.2350.20
52_I155_L1.2340.20
664_L726_V1.2340.20
664_L830_T1.2340.20
461_S760_L1.2320.20
330_L661_V1.2300.20
505_S583_V1.2280.20
191_L768_L1.2270.20
11_L14_L1.2260.20
76_N79_L1.2260.20
175_V550_E1.2250.20
822_S825_D1.2250.20
641_F822_S1.2190.20
400_R748_L1.2170.20
52_I804_I1.2130.20
479_T721_S1.2120.20
744_L833_L1.2100.20
435_W788_A1.2090.20
369_R615_H1.2080.20
426_F433_W1.2060.20
716_R800_S1.2060.20
554_V677_R1.2040.20
397_V790_N1.2030.19
162_V634_D1.2020.19
340_D527_T1.2020.19
478_G569_A1.2010.19
556_V715_L1.1990.19
695_V700_V1.1980.19
386_P454_G1.1910.19
169_K213_T1.1890.19
713_A806_L1.1890.19
79_L855_Q1.1890.19
565_L776_D1.1880.19
56_G683_E1.1880.19
202_D551_I1.1880.19
127_I340_D1.1860.19
303_T492_P1.1850.19
268_W277_G1.1820.19
62_L473_D1.1810.19
453_A648_L1.1800.19
766_M820_G1.1800.19
697_G760_L1.1790.19
49_S218_Q1.1770.19
534_G845_W1.1650.19
835_Y842_F1.1620.19
180_V643_D1.1590.19
202_D755_V1.1590.19
201_P542_F1.1580.19
792_L800_S1.1580.19
234_G384_R1.1580.19
696_L840_N1.1570.19
41_G81_H1.1560.19
88_N476_Q1.1560.19
157_Y295_V1.1520.18
790_N802_T1.1510.18
249_D380_I1.1500.18
397_V841_I1.1470.18
588_K633_V1.1460.18
440_K500_Q1.1450.18
177_E254_I1.1440.18
187_P443_F1.1410.18
160_E212_A1.1410.18
104_Q165_Q1.1390.18
155_L665_V1.1380.18
721_S818_I1.1370.18
839_E844_L1.1370.18
658_I670_I1.1370.18
401_L534_G1.1360.18
600_V722_S1.1360.18
535_R778_V1.1340.18
80_S351_L1.1330.18
618_L730_N1.1330.18
38_L833_L1.1330.18
100_A206_V1.1330.18
779_V804_I1.1270.18
766_M845_W1.1250.18
121_M661_V1.1230.18
114_T752_K1.1230.18
575_S861_N1.1220.18
755_V806_L1.1150.18
568_N836_H1.1140.18
396_G609_G1.1140.18
733_Q842_F1.1140.18
692_S755_V1.1110.18
228_D233_S1.1110.18
76_N736_M1.1100.18
385_W744_L1.1090.18
238_V280_G1.1070.18
64_Y67_G1.1060.18
399_G602_F1.1050.18
534_G835_Y1.1050.18
251_P546_L1.1050.18
62_L262_S1.1000.17
269_P746_L1.0990.17
17_L720_L1.0920.17
195_F800_S1.0880.17
446_M722_S1.0860.17
722_S828_S1.0860.17
568_N823_R1.0850.17
766_M816_A1.0850.17
594_G738_G1.0850.17
77_A432_R1.0840.17
141_Q507_A1.0840.17
464_T500_Q1.0840.17
382_E853_N1.0810.17
361_T736_M1.0800.17
42_T67_G1.0800.17
470_T759_W1.0780.17
565_L844_L1.0780.17
783_M832_N1.0780.17
330_L362_F1.0780.17
208_G674_L1.0770.17
469_S669_N1.0760.17
554_V722_S1.0760.17
185_N695_V1.0750.17
23_L337_K1.0750.17
838_E841_I1.0740.17
366_A620_G1.0730.17
307_A427_L1.0720.17
93_E491_K1.0710.17
386_P534_G1.0700.17
386_P567_G1.0690.17
697_G788_A1.0690.17
78_S648_L1.0660.17
580_Q614_G1.0620.17
369_R559_R1.0600.17
94_L316_F1.0580.17
648_L740_F1.0580.17
197_M250_L1.0580.17
229_W387_L1.0580.17
433_W456_G1.0570.17
23_L822_S1.0570.17
352_S449_T1.0560.17
88_N128_N1.0530.17
268_W426_F1.0520.17
814_M839_E1.0520.17
216_L755_V1.0490.16
156_R256_R1.0480.16
73_H163_K1.0470.16
257_Q295_V1.0470.16
42_T64_Y1.0400.16
293_A760_L1.0400.16
132_L391_K1.0360.16
396_G454_G1.0340.16
312_A633_V1.0310.16
411_E722_S1.0310.16
367_L438_W1.0300.16
175_V750_N1.0290.16
441_G528_L1.0290.16
608_Q776_D1.0290.16
100_A129_I1.0260.16
688_L758_G1.0260.16
690_D741_S1.0260.16
576_L732_K1.0250.16
367_L603_S1.0230.16
722_S822_S1.0220.16
543_K557_N1.0210.16
24_M829_G1.0210.16
561_D632_G1.0210.16
397_V741_S1.0200.16
158_Q164_F1.0200.16
86_L452_V1.0200.16
134_F288_A1.0200.16
405_L755_V1.0150.16
506_G859_E1.0140.16
806_L839_E1.0100.16
447_N641_F1.0070.16
86_L257_Q1.0070.16
646_W847_S1.0060.16
195_F804_I1.0050.16
353_G388_A1.0040.16
68_D683_E1.0030.16
100_A760_L1.0030.16
455_K467_D1.0030.16
59_I608_Q1.0020.16
59_I734_F1.0000.16
104_Q175_V0.9980.16
164_F211_T0.9970.16
189_V490_D0.9950.16
480_M521_S0.9940.15
802_T818_I0.9880.15
225_A480_M0.9840.15
10_A13_L0.9830.15
662_I720_L0.9830.15
596_L734_F0.9820.15
685_P708_P0.9810.15
643_D841_I0.9800.15
141_Q596_L0.9780.15
626_P731_P0.9770.15
23_L628_N0.9770.15
70_Q194_E0.9770.15
476_Q511_D0.9770.15
790_N825_D0.9750.15
534_G685_P0.9750.15
268_W602_F0.9740.15
201_P628_N0.9730.15
263_D508_L0.9710.15
352_S503_S0.9680.15
693_V801_S0.9660.15
164_F280_G0.9660.15
495_W540_F0.9650.15
557_N861_N0.9650.15
9_L21_T0.9650.15
214_L349_A0.9640.15
334_G399_G0.9620.15
190_K692_S0.9610.15
47_D95_D0.9610.15
750_N832_N0.9600.15
505_S529_K0.9600.15
129_I642_A0.9570.15
151_D163_K0.9570.15
441_G445_P0.9570.15
269_P427_L0.9570.15
306_Q342_I0.9560.15
288_A781_D0.9550.15
433_W571_W0.9530.15
533_D701_L0.9530.15
381_D408_H0.9520.15
803_K814_M0.9520.15
130_D299_L0.9510.15
458_W534_G0.9510.15
221_S755_V0.9490.15
59_I590_N0.9480.15
117_Q294_L0.9460.15
696_L758_G0.9430.15
141_Q324_D0.9430.15
268_W399_G0.9430.15
100_A164_F0.9410.15
81_H660_E0.9410.15
26_L755_V0.9390.15
407_A723_S0.9380.15
688_L738_G0.9370.15
59_I87_L0.9360.15
316_F362_F0.9350.15
433_W845_W0.9310.14
614_G708_P0.9310.14
741_S757_D0.9300.14
261_V724_E0.9300.14
633_V822_S0.9300.14
170_G822_S0.9290.14
344_Y371_K0.9290.14
322_S351_L0.9260.14
812_L831_V0.9260.14
44_I201_P0.9250.14
142_G686_L0.9250.14
444_T542_F0.9250.14
35_G44_I0.9240.14
382_E422_L0.9240.14
830_T856_A0.9240.14
439_G552_G0.9230.14
94_L185_N0.9230.14
155_L490_D0.9220.14
88_N719_N0.9200.14
232_N790_N0.9200.14
99_L736_M0.9190.14
306_Q475_L0.9190.14
367_L613_G0.9180.14
609_G708_P0.9170.14
684_E778_V0.9170.14
59_I93_E0.9150.14
21_T591_L0.9140.14
216_L490_D0.9140.14
376_D858_L0.9140.14
115_L351_L0.9130.14
571_W713_A0.9130.14
8_V527_T0.9110.14
171_Q178_L0.9110.14
802_T806_L0.9110.14
105_T681_T0.9090.14
282_K802_T0.9070.14
600_V822_S0.9070.14
539_Y773_D0.9060.14
131_K145_S0.9000.14
178_L466_T0.9000.14
705_L797_I0.8990.14
741_S761_A0.8980.14
10_A42_T0.8980.14
335_E631_N0.8970.14
664_L856_A0.8970.14
446_M843_T0.8960.14
522_V789_I0.8950.14
265_R507_A0.8930.14
412_L628_N0.8910.14
183_F316_F0.8910.14
420_D748_L0.8880.14
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173_L230_Q0.5530.09
664_L698_G0.5530.09
16_I120_A0.5520.09
215_N447_N0.5520.09
375_I829_G0.5520.09
806_L842_F0.5520.09
454_G571_W0.5520.09
264_G421_G0.5510.09
632_G659_A0.5510.09
11_L200_V0.5500.09
22_L299_L0.5500.09
197_M825_D0.5500.09
249_D260_T0.5490.09
626_P633_V0.5480.09
165_Q176_S0.5470.09
296_S583_V0.5470.09
95_D238_V0.5470.09
229_W433_W0.5470.09
707_M815_Q0.5470.09
264_G552_G0.5460.09
648_L795_M0.5460.09
713_A837_H0.5460.09
757_D760_L0.5450.09
308_G705_L0.5450.09
22_L301_V0.5450.09
525_P775_A0.5450.09
552_G845_W0.5420.09
630_V666_T0.5410.09
574_Q609_G0.5410.09
770_L822_S0.5400.09
169_K440_K0.5390.09
189_V680_W0.5380.09
363_E493_I0.5380.09
15_I20_L0.5370.09
602_F839_E0.5370.09
220_P765_P0.5360.09
87_L102_L0.5360.09
231_E687_L0.5360.09
34_A620_G0.5360.09
348_P658_I0.5350.09
97_A256_R0.5350.09
532_V719_N0.5350.09
260_T684_E0.5350.09
456_G766_M0.5350.09
519_G817_N0.5350.09
734_F818_I0.5340.09
155_L576_L0.5340.09
255_T315_N0.5340.09
421_G709_Q0.5330.09
176_S299_L0.5330.09
831_V840_N0.5330.09
18_V572_P0.5330.09
23_L729_V0.5330.09
667_A722_S0.5330.09
251_P602_F0.5320.09
839_E842_F0.5320.09
650_T724_E0.5310.09
96_S751_E0.5310.09
708_P746_L0.5310.09
348_P613_G0.5300.09
129_I581_P0.5290.09
71_L733_Q0.5290.09
525_P779_V0.5280.09
754_I775_A0.5280.09
333_T346_R0.5280.09
504_F856_A0.5280.09
42_T621_G0.5270.09
248_L549_G0.5270.09
67_G600_V0.5270.09
107_Q780_K0.5270.09
325_N476_Q0.5270.09
213_T243_N0.5270.09
44_I385_W0.5260.09
98_C534_G0.5260.09
138_Q214_L0.5250.09
582_L845_W0.5240.09
665_V755_V0.5240.09
164_F197_M0.5230.09
46_L741_S0.5230.09
729_V739_A0.5230.09
52_I412_L0.5220.09
534_G766_M0.5220.09
622_S783_M0.5220.09
108_S176_S0.5210.09
184_E249_D0.5210.09
98_C268_W0.5200.09
511_D606_P0.5200.09
264_G396_G0.5200.09
446_M790_N0.5200.09
133_I700_V0.5190.09
380_I411_E0.5190.09
206_V493_I0.5190.09
373_R622_S0.5190.09
643_D677_R0.5180.09
11_L722_S0.5180.09
6_K611_R0.5180.09
626_P639_F0.5180.09
475_L621_G0.5170.09
387_L571_W0.5170.09
626_P822_S0.5170.09
597_Y617_V0.5170.09
421_G708_P0.5160.09
59_I154_Q0.5160.09
153_Q604_A0.5160.09
338_Q726_V0.5160.09
66_V254_I0.5160.09
94_L133_I0.5150.09
403_A614_G0.5150.09
547_H702_M0.5150.09
19_P756_K0.5130.09
133_I483_E0.5130.09
456_G845_W0.5130.09
616_G667_A0.5130.09
251_P487_L0.5120.09
396_G574_Q0.5120.09
651_R821_T0.5120.09
275_L387_L0.5110.09
523_L847_S0.5110.09
229_W454_G0.5100.09
557_N720_L0.5100.09
650_T760_L0.5090.09
88_N228_D0.5080.09
119_Q317_G0.5080.09
217_P249_D0.5080.09
255_T349_A0.5070.09
61_D94_L0.5070.09
239_L836_H0.5070.09
570_W639_F0.5070.09
243_N254_I0.5060.09
106_E147_A0.5040.09
64_Y741_S0.5040.09
785_A827_K0.5040.09
24_M749_N0.5030.09
107_Q127_I0.5030.09
770_L814_M0.5020.09
345_A370_S0.5010.09
366_A402_Q0.5000.09
628_N664_L0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4jtmA 2 0.0751 14.5 0.987 Contact Map
4pj0U 1 0.1069 8.4 0.988 Contact Map
4hs5A 1 0.1058 7.6 0.988 Contact Map
4ftgE 1 0.0182 7.6 0.988 Contact Map
1wubA 1 0.1843 7.3 0.988 Contact Map
4g3oA 1 0.0603 6.9 0.989 Contact Map
1y0gA 2 0.1843 6.8 0.989 Contact Map
3j2wE 1 0.0319 6.6 0.989 Contact Map
1vsy5 1 0.0933 6.1 0.989 Contact Map
4e9jA 2 0.1889 5.7 0.989 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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