GREMLIN Database
YCCM - Putative electron transport protein YccM
UniProt: P52636 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13234
Length: 357 (309)
Sequences: 1790 (1134)
Seq/√Len: 64.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
144_C147_P5.6061.00
147_P150_L5.3851.00
152_I156_G5.3491.00
135_L165_F4.6701.00
151_D154_L4.6541.00
146_L150_L4.5841.00
144_C148_R4.1211.00
121_W296_F4.1121.00
151_D156_G3.9641.00
139_L161_L3.7431.00
222_W226_L3.5191.00
140_F158_K3.3381.00
159_Y212_L3.3361.00
237_S241_P3.2571.00
146_L149_W3.1891.00
330_A334_G3.1521.00
315_M319_V2.8311.00
139_L157_V2.6851.00
297_S301_P2.6071.00
240_S300_K2.5601.00
75_W78_I2.5461.00
34_A38_L2.5401.00
209_T213_I2.3931.00
153_P157_V2.3901.00
196_F201_G2.3781.00
134_D138_K2.3661.00
38_L42_M2.3371.00
186_S190_D2.3051.00
179_Y184_P2.2291.00
151_D155_R2.1891.00
237_S243_K2.1681.00
157_V161_L2.0981.00
145_V150_L2.0721.00
148_R152_I2.0301.00
180_F183_S2.0081.00
247_N295_T1.9291.00
322_I326_V1.8701.00
19_K22_W1.8541.00
162_L166_I1.8201.00
169_A211_L1.8141.00
33_K37_L1.7901.00
47_A50_F1.7701.00
144_C149_W1.7601.00
19_K26_R1.7571.00
28_A31_W1.7471.00
118_F122_L1.7411.00
22_W26_R1.7070.99
202_T205_L1.6740.99
109_V318_L1.6700.99
209_T218_I1.6490.99
163_S208_V1.6390.99
144_C150_L1.6380.99
120_S279_T1.5980.99
147_P151_D1.5730.99
153_P156_G1.5680.99
145_V148_R1.5470.99
48_I52_Y1.5390.99
202_T206_I1.5360.99
70_G73_E1.5250.99
180_F187_V1.5020.99
24_D29_T1.4980.98
198_R202_T1.4870.98
190_D194_L1.4760.98
102_L328_G1.4600.98
316_T320_L1.4370.98
136_G141_G1.4340.98
252_I290_V1.3900.98
47_A52_Y1.3860.97
44_I47_A1.3770.97
291_A296_F1.3720.97
258_A268_D1.3520.97
179_Y183_S1.3480.97
30_T33_K1.3450.97
21_P133_G1.3400.97
205_L209_T1.3250.97
336_W339_P1.3230.97
41_A45_Y1.2930.96
152_I155_R1.2830.96
179_Y187_V1.2590.96
157_V160_L1.2580.96
150_L154_L1.2550.95
183_S186_S1.2540.95
113_L314_L1.2490.95
260_N287_S1.2480.95
167_Y205_L1.2420.95
230_G237_S1.2270.95
256_K287_S1.2230.95
27_N30_T1.2160.95
221_A225_Y1.2080.94
291_A295_T1.2040.94
31_W35_T1.1950.94
194_L201_G1.1940.94
204_T208_V1.1920.94
209_T325_A1.1830.94
19_K23_N1.1820.94
95_S331_M1.1780.94
22_W29_T1.1740.94
181_M187_V1.1730.94
163_S217_F1.1720.93
49_T52_Y1.1700.93
196_F200_M1.1680.93
112_L316_T1.1450.93
22_W28_A1.1350.92
154_L157_V1.1350.92
50_F185_Y1.1270.92
159_Y162_L1.1270.92
135_L138_K1.1200.92
329_Y333_A1.1040.91
326_V330_A1.0760.90
195_D198_R1.0730.90
306_K334_G1.0720.90
159_Y217_F1.0680.90
218_I221_A1.0630.90
170_L208_V1.0590.89
147_P154_L1.0590.89
44_I168_I1.0560.89
139_L154_L1.0530.89
252_I256_K1.0520.89
318_L322_I1.0500.89
128_L169_A1.0450.89
106_A110_I1.0410.89
255_G259_K1.0410.89
146_L151_D1.0390.89
267_V273_V1.0380.89
210_V214_A1.0380.89
22_W46_I1.0350.88
23_N137_N1.0240.88
149_W153_P1.0210.88
22_W25_W1.0210.88
319_V336_W1.0190.88
26_R47_A1.0180.88
46_I72_I1.0160.87
20_L155_R1.0070.87
244_I296_F1.0020.87
28_A47_A0.9930.86
77_P80_G0.9880.86
20_L26_R0.9870.86
18_G21_P0.9860.86
179_Y185_Y0.9840.86
114_L117_A0.9810.86
316_T319_V0.9730.85
24_D290_V0.9730.85
113_L307_A0.9710.85
105_V113_L0.9660.85
191_V194_L0.9650.85
340_V343_E0.9640.85
129_S215_S0.9630.84
29_T35_T0.9520.84
20_L23_N0.9490.84
319_V323_M0.9480.84
197_F200_M0.9450.83
190_D195_D0.9440.83
325_A329_Y0.9430.83
312_G315_M0.9430.83
322_I329_Y0.9360.83
244_I280_G0.9320.82
32_R35_T0.9300.82
23_N26_R0.9250.82
164_F329_Y0.9240.82
244_I294_L0.9130.81
159_Y163_S0.9120.81
333_A336_W0.9040.80
193_M196_F0.8920.80
258_A267_V0.8890.79
224_R277_E0.8870.79
103_L106_A0.8870.79
35_T38_L0.8860.79
297_S302_A0.8860.79
189_M192_K0.8840.79
36_Q40_L0.8800.79
29_T46_I0.8760.78
121_W215_S0.8720.78
244_I282_M0.8700.78
137_N142_R0.8690.78
180_F185_Y0.8670.78
52_Y68_R0.8650.77
33_K39_L0.8650.77
82_M87_S0.8650.77
23_N35_T0.8590.77
306_K309_A0.8580.77
206_I210_V0.8570.77
323_M326_V0.8550.77
32_R36_Q0.8490.76
26_R29_T0.8470.76
221_A313_W0.8470.76
36_Q39_L0.8450.76
29_T32_R0.8440.76
291_A297_S0.8420.76
245_R302_A0.8410.75
240_S308_F0.8370.75
39_L42_M0.8360.75
210_V213_I0.8320.75
42_M46_I0.8280.74
140_F155_R0.8270.74
190_D193_M0.8250.74
135_L161_L0.8220.74
328_G332_Y0.8160.73
47_A126_G0.8130.73
35_T46_I0.8120.73
42_M45_Y0.8060.72
330_A337_Q0.7990.72
21_P24_D0.7980.72
32_R124_P0.7930.71
35_T47_A0.7920.71
32_R41_A0.7920.71
102_L325_A0.7870.71
158_K277_E0.7840.70
189_M193_M0.7820.70
246_R273_V0.7770.70
26_R52_Y0.7760.69
27_N35_T0.7750.69
254_C257_C0.7740.69
94_P98_A0.7720.69
178_H181_M0.7710.69
251_C257_C0.7710.69
138_K142_R0.7700.69
323_M327_I0.7700.69
307_A310_L0.7680.69
238_L246_R0.7680.69
107_F206_I0.7670.69
80_G89_V0.7650.68
107_F282_M0.7650.68
244_I285_V0.7640.68
282_M285_V0.7640.68
300_K305_K0.7640.68
322_I333_A0.7630.68
39_L43_N0.7610.68
239_L300_K0.7540.67
136_G162_L0.7490.67
265_I277_E0.7450.66
180_F191_V0.7410.66
168_I207_S0.7400.66
111_S115_K0.7400.66
94_P97_H0.7380.66
166_I170_L0.7360.65
19_K28_A0.7340.65
336_W343_E0.7280.64
213_I217_F0.7250.64
320_L327_I0.7240.64
131_L165_F0.7240.64
224_R263_S0.7230.64
177_I259_K0.7230.64
118_F235_V0.7220.64
330_A333_A0.7220.64
24_D27_N0.7220.64
93_L96_V0.7180.63
97_H101_M0.7150.63
327_I337_Q0.7150.63
277_E280_G0.7150.63
234_G276_V0.7130.63
292_S298_L0.7130.63
324_F327_I0.7120.63
102_L324_F0.7110.63
245_R297_S0.7100.63
246_R266_P0.7080.62
26_R48_I0.7080.62
250_S292_S0.7040.62
43_N50_F0.7010.62
298_L305_K0.7010.62
335_V338_S0.7000.61
309_A312_G0.6990.61
21_P29_T0.6980.61
37_L301_P0.6980.61
146_L152_I0.6950.61
35_T39_L0.6920.61
156_G160_L0.6870.60
108_I232_L0.6860.60
130_E224_R0.6860.60
43_N46_I0.6850.60
22_W259_K0.6830.60
33_K36_Q0.6830.60
251_C254_C0.6830.60
72_I83_N0.6820.59
121_W214_A0.6820.59
198_R201_G0.6800.59
155_R277_E0.6780.59
76_L79_A0.6760.59
128_L211_L0.6760.59
31_W34_A0.6760.59
344_L349_I0.6750.59
234_G240_S0.6730.58
162_L231_A0.6720.58
28_A35_T0.6710.58
230_G276_V0.6700.58
19_K52_Y0.6700.58
319_V326_V0.6690.58
285_V294_L0.6680.58
136_G140_F0.6660.58
35_T121_W0.6650.58
18_G22_W0.6610.57
231_A273_V0.6560.56
262_P283_T0.6550.56
100_A210_V0.6530.56
133_G263_S0.6510.56
93_L118_F0.6500.56
80_G235_V0.6490.56
44_I207_S0.6470.55
182_L200_M0.6470.55
148_R156_G0.6450.55
132_I166_I0.6410.55
98_A328_G0.6410.55
263_S283_T0.6410.55
109_V324_F0.6390.55
327_I330_A0.6360.54
306_K323_M0.6350.54
119_C123_C0.6340.54
278_C284_C0.6340.54
123_C284_C0.6340.54
123_C278_C0.6340.54
119_C278_C0.6340.54
119_C284_C0.6340.54
51_W72_I0.6330.54
263_S321_G0.6320.54
147_P156_G0.6320.54
163_S333_A0.6310.54
162_L216_L0.6300.54
29_T130_E0.6290.53
120_S264_R0.6280.53
38_L45_Y0.6270.53
313_W317_L0.6270.53
147_P152_I0.6270.53
91_G113_L0.6200.52
196_F204_T0.6200.52
29_T36_Q0.6190.52
22_W256_K0.6190.52
118_F222_W0.6190.52
70_G74_G0.6170.52
20_L28_A0.6160.52
316_T333_A0.6160.52
341_P345_Y0.6110.51
101_M108_I0.6080.51
38_L163_S0.6060.51
28_A52_Y0.6060.51
149_W152_I0.6040.50
23_N29_T0.6040.50
177_I187_V0.6030.50
39_L128_L0.6030.50
19_K24_D0.6030.50
119_C227_C0.6000.50
227_C278_C0.6000.50
227_C284_C0.6000.50
123_C227_C0.6000.50
22_W47_A0.6000.50
225_Y277_E0.6000.50
23_N142_R0.5950.49
214_A217_F0.5940.49
266_P273_V0.5920.49
31_W48_I0.5920.49
342_E348_L0.5910.49
35_T52_Y0.5910.49
27_N31_W0.5900.49
164_F248_A0.5890.49
315_M337_Q0.5880.49
47_A51_W0.5870.49
345_Y348_L0.5850.48
252_I289_P0.5830.48
112_L235_V0.5830.48
236_V243_K0.5820.48
298_L301_P0.5810.48
257_C288_C0.5810.48
179_Y182_L0.5800.48
40_L128_L0.5780.47
344_L348_L0.5770.47
164_F168_I0.5750.47
300_K306_K0.5750.47
210_V230_G0.5740.47
93_L102_L0.5730.47
157_V322_I0.5720.47
235_V266_P0.5710.47
253_D268_D0.5690.46
102_L321_G0.5680.46
154_L166_I0.5680.46
43_N48_I0.5650.46
217_F225_Y0.5640.46
84_L225_Y0.5630.46
167_Y208_V0.5630.46
265_I269_K0.5630.46
104_L108_I0.5630.46
229_Y233_M0.5620.46
131_L294_L0.5600.45
110_I117_A0.5590.45
190_D200_M0.5590.45
144_C152_I0.5580.45
21_P26_R0.5580.45
331_M340_V0.5570.45
124_P158_K0.5560.45
34_A37_L0.5550.45
343_E349_I0.5550.45
179_Y188_V0.5540.45
28_A48_I0.5530.45
320_L334_G0.5520.44
123_C261_C0.5510.44
119_C261_C0.5510.44
261_C284_C0.5510.44
261_C278_C0.5510.44
339_P349_I0.5510.44
178_H204_T0.5510.44
258_A273_V0.5480.44
19_K35_T0.5480.44
33_K40_L0.5470.44
295_T301_P0.5450.44
35_T40_L0.5450.44
197_F201_G0.5440.44
203_A207_S0.5440.44
223_C284_C0.5430.43
223_C278_C0.5430.43
123_C223_C0.5430.43
119_C223_C0.5430.43
138_K320_L0.5420.43
308_F314_L0.5420.43
277_E282_M0.5410.43
69_P73_E0.5400.43
299_Q303_A0.5390.43
120_S125_V0.5340.42
50_F68_R0.5330.42
337_Q349_I0.5320.42
136_G216_L0.5320.42
23_N161_L0.5320.42
252_I268_D0.5320.42
26_R35_T0.5310.42
320_L341_P0.5300.42
341_P348_L0.5290.42
263_S279_T0.5280.42
241_P276_V0.5280.42
111_S116_K0.5270.42
344_L347_R0.5270.42
154_L158_K0.5260.41
40_L48_I0.5260.41
115_K267_V0.5250.41
307_A315_M0.5240.41
304_N307_A0.5220.41
29_T52_Y0.5210.41
235_V298_L0.5210.41
250_S287_S0.5190.41
29_T47_A0.5180.41
339_P343_E0.5170.40
171_L188_V0.5170.40
252_I279_T0.5160.40
227_C261_C0.5160.40
108_I236_V0.5150.40
247_N302_A0.5140.40
154_L259_K0.5140.40
130_E348_L0.5140.40
22_W48_I0.5130.40
305_K323_M0.5130.40
295_T299_Q0.5130.40
309_A323_M0.5120.40
18_G24_D0.5120.40
182_L190_D0.5120.40
338_S341_P0.5100.40
318_L336_W0.5100.40
334_G342_E0.5090.40
223_C227_C0.5080.39
28_A44_I0.5070.39
26_R43_N0.5060.39
33_K44_I0.5060.39
104_L107_F0.5060.39
137_N143_Q0.5050.39
325_A339_P0.5040.39
160_L333_A0.5020.39
313_W316_T0.5020.39
244_I273_V0.5010.39
318_L325_A0.5000.39
250_S268_D0.5000.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4p6vA 1 0.6415 99 0.859 Contact Map
1iqzA 1 0.1905 99 0.862 Contact Map
4z3xE 2 0.3754 98.9 0.866 Contact Map
1hfeL 2 0.3838 98.9 0.867 Contact Map
1jb0C 1 0.1961 98.9 0.867 Contact Map
1dwlA 1 0.1513 98.8 0.869 Contact Map
3gyxB 1 0.3193 98.8 0.869 Contact Map
1jnrB 1 0.2829 98.8 0.871 Contact Map
4id8A 1 0.1597 98.8 0.872 Contact Map
3i9v9 1 0.3417 98.8 0.872 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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