GREMLIN Database
FLIJ - Flagellar FliJ protein
UniProt: P52613 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG20267
Length: 147 (140)
Sequences: 588 (434)
Seq/√Len: 36.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
46_Q77_E4.1021.00
29_R98_L3.6221.00
28_M97_A3.5981.00
18_V108_L3.0881.00
36_E91_T2.9071.00
109_Q112_Q2.8831.00
116_E120_T2.5401.00
32_C91_T2.3451.00
20_D23_R2.2520.99
18_V105_K2.2390.99
15_E19_E2.1390.99
57_M60_G2.0930.99
10_L114_L2.0420.99
36_E40_K1.9980.98
138_A141_A1.8710.98
125_A129_L1.8060.97
10_L111_W1.7190.96
132_K136_E1.7030.96
32_C94_V1.6190.94
63_S66_W1.6010.94
43_I84_R1.5860.94
112_Q116_E1.5720.94
42_L79_A1.5610.93
40_K44_D1.5510.93
88_N92_Q1.5300.93
106_Q110_A1.5280.93
119_S122_A1.5010.92
34_Q38_Q1.4530.91
127_N130_D1.4470.90
12_D16_K1.4440.90
124_L128_R1.3920.89
51_N122_A1.3850.88
105_K109_Q1.3690.88
4_H122_A1.3500.87
45_Y76_L1.3460.87
32_C87_L1.3390.87
86_Q89_Q1.3390.87
76_L117_R1.3280.86
7_L77_E1.3160.86
29_R82_Q1.3050.85
85_Q88_N1.3040.85
126_E129_L1.2930.85
11_K115_Q1.2890.84
45_Y80_I1.2760.84
21_A25_L1.2460.82
82_Q139_Q1.2070.80
110_A139_Q1.2020.80
35_A108_L1.2010.80
76_L110_A1.1870.79
10_L60_G1.1840.79
10_L105_K1.1740.78
75_T118_Q1.1640.78
123_L127_N1.1600.77
139_Q143_M1.1570.77
7_L11_K1.1470.77
130_D134_M1.1470.77
7_L114_L1.1440.76
54_N117_R1.1330.76
16_K32_C1.1300.76
70_Q101_W1.1260.75
53_L137_F1.1140.74
116_E132_K1.1010.74
6_A122_A1.0920.73
73_I91_T1.0890.73
60_G117_R1.0820.72
47_N73_I1.0810.72
17_E104_K1.0800.72
98_L129_L1.0670.71
132_K137_F1.0670.71
61_I66_W1.0670.71
5_G118_Q1.0570.70
50_R66_W1.0440.69
10_L19_E1.0150.67
14_A104_K1.0110.67
69_Y83_H1.0030.66
98_L102_R0.9980.66
53_L73_I0.9970.66
38_Q71_Q0.9850.65
136_E141_A0.9770.64
70_Q102_R0.9670.63
89_Q96_I0.9650.63
18_V75_T0.9600.63
21_A38_Q0.9600.63
29_R94_V0.9460.62
88_N91_T0.9450.62
16_K20_D0.9370.61
39_L80_I0.9320.61
14_A41_M0.9210.60
101_W105_K0.9160.59
39_L87_L0.9110.59
76_L80_I0.9100.59
23_R27_E0.8990.58
72_F135_D0.8920.57
105_K138_A0.8910.57
34_Q138_A0.8770.56
75_T128_R0.8670.55
129_L133_K0.8650.55
28_M32_C0.8590.54
49_Y101_W0.8570.54
33_Q130_D0.8560.54
46_Q69_Y0.8500.54
6_A118_Q0.8350.52
56_D67_I0.8320.52
14_A25_L0.8280.52
21_A103_E0.8270.52
120_T124_L0.8240.51
9_T41_M0.8230.51
38_Q141_A0.8120.50
52_N73_I0.7990.49
123_L129_L0.7890.48
60_G69_Y0.7880.48
49_Y69_Y0.7850.48
54_N57_M0.7830.48
55_S59_A0.7810.48
128_R136_E0.7810.48
107_R111_W0.7800.47
128_R138_A0.7790.47
55_S62_T0.7740.47
31_G84_R0.7560.45
83_H98_L0.7490.45
44_D73_I0.7390.44
5_G11_K0.7390.44
24_L100_S0.7390.44
41_M75_T0.7310.43
31_G63_S0.7220.42
76_L107_R0.7160.42
59_A120_T0.7150.42
62_T81_T0.7140.42
15_E138_A0.7120.42
93_K97_A0.7070.41
9_T118_Q0.7010.41
126_E130_D0.7000.41
137_F140_R0.6970.40
12_D15_E0.6950.40
69_Y77_E0.6940.40
20_D39_L0.6900.40
79_A82_Q0.6840.39
32_C128_R0.6820.39
10_L89_Q0.6820.39
104_K107_R0.6790.39
46_Q49_Y0.6780.39
95_D98_L0.6760.38
9_T138_A0.6760.38
4_H106_Q0.6720.38
75_T121_A0.6700.38
18_V22_A0.6600.37
121_A136_E0.6520.37
49_Y53_L0.6510.36
66_W108_L0.6410.36
138_A143_M0.6370.35
70_Q97_A0.6360.35
46_Q130_D0.6330.35
6_A9_T0.6320.35
38_Q45_Y0.6290.35
66_W69_Y0.6270.35
36_E80_I0.6270.35
16_K58_S0.6270.35
62_T85_Q0.6260.34
101_W110_A0.6180.34
71_Q75_T0.6100.33
27_E30_R0.6090.33
18_V118_Q0.6070.33
88_N95_D0.6060.33
93_K96_I0.6060.33
36_E58_S0.6030.33
17_E48_E0.5930.32
15_E126_E0.5890.32
95_D103_E0.5870.31
5_G10_L0.5840.31
33_Q74_Q0.5790.31
83_H90_W0.5780.31
84_R87_L0.5740.30
62_T133_K0.5740.30
49_Y114_L0.5740.30
12_D103_E0.5660.30
35_A87_L0.5640.30
28_M31_G0.5640.30
25_L63_S0.5590.29
20_D55_S0.5480.29
66_W107_R0.5470.28
18_V38_Q0.5430.28
94_V137_F0.5430.28
126_E137_F0.5410.28
53_L133_K0.5390.28
21_A93_K0.5380.28
75_T79_A0.5370.28
41_M68_N0.5360.28
118_Q137_F0.5350.28
13_L118_Q0.5350.28
10_L53_L0.5340.28
121_A125_A0.5300.27
21_A104_K0.5300.27
27_E34_Q0.5260.27
9_T22_A0.5200.27
139_Q142_A0.5200.27
75_T82_Q0.5190.27
15_E18_V0.5160.26
25_L140_R0.5140.26
10_L113_T0.5140.26
7_L10_L0.5130.26
46_Q67_I0.5130.26
33_Q36_E0.5130.26
65_R70_Q0.5110.26
71_Q91_T0.5100.26
21_A97_A0.5090.26
42_L80_I0.5080.26
64_N78_K0.5050.26
42_L131_Q0.5030.25
12_D115_Q0.5010.25
83_H87_L0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ajwA 2 0.9116 100 0.273 Contact Map
3k29A 1 0.9796 99.9 0.4 Contact Map
4mh6A 1 0.9388 93 0.85 Contact Map
4q4gX 1 0 15.6 0.924 Contact Map
2b5uA 1 0.9252 9 0.932 Contact Map
4cgkA 3 1 7 0.935 Contact Map
4dndA 1 0.5578 6.2 0.937 Contact Map
4j2cA 1 0.5918 3.9 0.942 Contact Map
3vjfA 2 0.6735 3.5 0.944 Contact Map
3mq9A 4 0.6122 3.4 0.944 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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