EMRY - ECOLI - GREMLIN Contacts

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EMRY - Probable multidrug resistance protein EmrY

UniProt:	P52600	Sequences: MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSLSTNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWESTSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNKIDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSSSQIMDKYYGSLSGVLNEINNEITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTAKGVG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13283
Length:	512 (418)
Sequences:	41590 (29721)
Seq/√Len:	1453.7

ECOLI - EMRY EMRB MDTD HSRA YEBQ NANT UHPC RHMT UHPT GALP ARAE DGOT XYLE PROP YAAU GARP YDJE MDFA KGTP SHIA YHJE EXUT YDJK YJJL BCR GLPT NEPI MDTM ENTS MHPT YGCS YIHN GUDP NARU YQCE FUCP MDTG YJHB YNFM NARK YDFJ EMRD YIHP FSR YAJR SETC YHJX YGAY YDHC YDHP AMPG SETA YDIN SOTB SETB MDTH YDIM TSGA MDTL YBJJ ARAJ YIHO UIDB YDEE XAPB YJIJ NUPG LPLT YHHS CYNX MELB YAGG YEAN YEGT YICJ YFCJ LACY YCAD HCAT
BACSU - YHCA BMR3 YFIU YUSP LMRB YUBD YCNB MMR TCRB YVKA YWOD YYBO CSBC GLPT YFNC YYAJ YNCC YWFA GUDP YFIG ARAE YWTG YDGK YBFB YVMA EXUT IOLT IOLF YDEG BMR2 YFHI NAIP YDDS YITG YYBF YFIS YCXA YTBD YXLH YKUC BMR1 YFMO YXAM NASA YDER CSBX YVQJ GUTA YJBB YFKL YQJV YYCB YFMI YBCL YCEJ PBUE YUXJ YHJO YOAB YWOG YFKF YJMB NARK BBEX GLCP YQGE YWBF YNAJ YTTB
HALSA - O54630 Q9HSM8 Q9HS33 Q9HSK3 Q9HRX5 Q9HPD6 Q9HMQ8 Q9HN67 Q9HMR5
SULSO - Q97VC8 Q97YH0 Q97U91 Q97Y15 Q97WR9 Q97X47 Q97VB9 Q97YY8 Q97U43 Q97WR1 Q97U99 Q97YL8 Q97UD8 Q97VV2 Q97U80 Q97VU3 Q7LX71 Q97Y43 Q7LX65 Q97V89 Q97VB7 Q97UY7 Q97U98 Q97UR4 Q97VT2 Q97WS7 Q980K3 Q97Y11 Q97XW7 Q97U76 Q97X63 Q97WT1 Q97ZC9 Q97X92 Q97YG2 Q97X02 Q97Z36 Q97VD1 Q97Z07 Q97VQ5 Q97Z05 Q97UJ4 Q97WP8 Q97YI4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
104_T	108_V	5.272	1.00
94_S	182_G	4.095	1.00
101_S	176_L	3.735	1.00
92_F	119_M	3.622	1.00
99_M	112_F	3.602	1.00
354_W	371_P	3.216	1.00
216_G	249_L	3.214	1.00
107_D	111_F	3.161	1.00
394_L	402_A	2.821	1.00
105_N	108_V	2.738	1.00
212_L	255_W	2.671	1.00
65_A	114_V	2.624	1.00
82_E	133_R	2.610	1.00
50_A	106_L	2.521	1.00
306_N	309_W	2.509	1.00
16_L	139_K	2.474	1.00
61_S	114_V	2.463	1.00
87_L	190_L	2.453	1.00
208_P	255_W	2.429	1.00
282_T	413_S	2.366	1.00
267_S	398_K	2.328	1.00
100_C	112_F	2.316	1.00
324_I	377_F	2.305	1.00
320_M	373_F	2.304	1.00
223_M	242_T	2.294	1.00
51_S	54_E	2.170	1.00
96_S	115_V	2.162	1.00
187_T	191_T	2.139	1.00
215_L	248_S	2.136	1.00
169_F	173_W	2.103	1.00
69_A	118_L	2.095	1.00
139_K	142_F	2.059	1.00
286_L	417_G	2.058	1.00
24_S	150_T	2.026	1.00
54_E	106_L	2.007	1.00
395_P	398_K	2.005	1.00
96_S	119_M	1.990	1.00
220_L	245_S	1.981	1.00
96_S	112_F	1.956	1.00
265_D	398_K	1.945	1.00
89_S	122_P	1.926	1.00
73_T	122_P	1.925	1.00
250_I	254_I	1.889	1.00
98_L	102_L	1.873	1.00
43_T	46_G	1.867	1.00
135_Y	143_A	1.857	1.00
108_V	112_F	1.849	1.00
290_G	421_T	1.845	1.00
87_L	186_L	1.844	1.00
83_L	87_L	1.840	1.00
98_L	179_V	1.840	1.00
103_S	108_V	1.822	1.00
106_L	110_I	1.816	1.00
239_I	243_V	1.802	1.00
136_P	139_K	1.789	1.00
366_T	370_L	1.776	1.00
165_I	173_W	1.775	1.00
40_A	166_C	1.767	1.00
300_Q	310_A	1.762	1.00
305_Y	313_A	1.758	1.00
20_T	135_Y	1.748	1.00
330_R	334_K	1.719	1.00
351_C	375_Q	1.710	1.00
167_D	308_I	1.677	1.00
100_C	109_L	1.669	1.00
58_V	109_L	1.656	1.00
227_G	232_W	1.652	1.00
50_A	54_E	1.635	1.00
61_S	110_I	1.628	1.00
347_M	378_A	1.619	1.00
189_C	193_L	1.605	1.00
219_G	241_L	1.583	1.00
289_S	414_G	1.582	1.00
305_Y	309_W	1.580	1.00
170_S	173_W	1.579	1.00
28_F	154_A	1.567	1.00
91_T	186_L	1.567	1.00
40_A	174_I	1.558	1.00
78_Q	400_A	1.557	1.00
103_S	112_F	1.554	1.00
45_S	55_G	1.547	1.00
298_L	303_M	1.535	1.00
17_W	21_I	1.534	1.00
77_A	126_L	1.530	1.00
226_K	230_L	1.512	1.00
206_N	209_G	1.510	1.00
19_V	134_N	1.510	1.00
26_A	86_F	1.508	1.00
309_W	312_L	1.504	1.00
68_I	214_V	1.489	1.00
255_W	259_S	1.489	1.00
173_W	180_P	1.459	1.00
351_C	378_A	1.440	1.00
219_G	248_S	1.437	1.00
137_P	140_R	1.427	1.00
364_D	367_G	1.427	1.00
240_I	244_V	1.417	1.00
216_G	245_S	1.414	1.00
164_Y	168_N	1.414	1.00
88_L	92_F	1.411	1.00
344_S	381_C	1.410	1.00
25_L	185_V	1.402	1.00
254_I	258_T	1.400	1.00
99_M	108_V	1.398	1.00
339_L	342_T	1.397	1.00
76_L	85_L	1.382	1.00
87_L	189_C	1.377	1.00
36_I	174_I	1.377	1.00
188_L	192_L	1.375	1.00
351_C	371_P	1.371	1.00
94_S	179_V	1.370	1.00
222_I	226_K	1.368	1.00
167_D	306_N	1.360	1.00
275_T	279_V	1.351	1.00
212_L	248_S	1.338	1.00
365_F	369_I	1.336	1.00
216_G	248_S	1.335	1.00
107_D	110_I	1.328	1.00
278_I	409_F	1.328	1.00
272_R	276_I	1.312	1.00
69_A	121_G	1.310	1.00
236_S	240_I	1.310	1.00
349_A	353_Y	1.309	1.00
262_P	265_D	1.306	1.00
141_T	333_N	1.295	1.00
76_L	80_I	1.291	1.00
309_W	313_A	1.287	1.00
219_G	244_V	1.276	1.00
330_R	333_N	1.276	1.00
366_T	369_I	1.276	1.00
18_C	192_L	1.273	1.00
77_A	82_E	1.271	1.00
94_S	186_L	1.269	1.00
97_S	178_N	1.262	1.00
428_R	432_H	1.260	1.00
207_L	211_T	1.257	1.00
81_G	84_R	1.256	1.00
75_R	79_R	1.249	1.00
22_A	185_V	1.242	1.00
223_M	245_S	1.238	1.00
95_L	99_M	1.237	1.00
370_L	373_F	1.237	1.00
428_R	431_L	1.237	1.00
329_G	333_N	1.233	1.00
84_R	88_L	1.224	1.00
317_I	376_G	1.219	1.00
62_F	120_A	1.217	1.00
284_A	382_F	1.215	1.00
22_A	188_L	1.208	1.00
204_K	261_N	1.207	1.00
104_T	107_D	1.193	1.00
132_L	140_R	1.189	1.00
22_A	192_L	1.187	1.00
274_F	278_I	1.183	1.00
299_L	368_I	1.181	1.00
259_S	262_P	1.178	1.00
92_F	96_S	1.175	1.00
65_A	117_G	1.166	1.00
244_V	248_S	1.161	1.00
346_L	350_V	1.160	1.00
226_K	229_D	1.153	1.00
33_D	36_I	1.151	1.00
43_T	47_F	1.149	1.00
164_Y	308_I	1.146	1.00
277_G	390_S	1.143	1.00
253_V	257_S	1.142	1.00
84_R	195_G	1.137	1.00
245_S	249_L	1.136	1.00
100_C	175_F	1.135	1.00
215_L	219_G	1.133	1.00
264_L	267_S	1.132	1.00
87_L	91_T	1.131	1.00
269_F	275_T	1.130	1.00
57_W	61_S	1.128	1.00
31_M	151_V	1.125	1.00
353_Y	356_S	1.122	1.00
94_S	183_I	1.121	1.00
257_S	267_S	1.120	1.00
348_Y	378_A	1.117	1.00
186_L	190_L	1.115	1.00
223_M	238_I	1.107	1.00
327_L	330_R	1.107	1.00
179_V	183_I	1.095	1.00
16_L	135_Y	1.086	1.00
254_I	257_S	1.083	1.00
331_Y	335_I	1.071	1.00
183_I	187_T	1.071	1.00
212_L	251_S	1.068	1.00
26_A	90_V	1.067	1.00
267_S	270_K	1.065	1.00
353_Y	357_V	1.056	1.00
161_L	164_Y	1.055	1.00
271_S	275_T	1.051	1.00
132_L	399_F	1.049	1.00
354_W	357_V	1.046	1.00
165_I	177_I	1.044	1.00
367_G	371_P	1.043	1.00
328_I	381_C	1.041	1.00
209_G	255_W	1.038	1.00
224_L	227_G	1.038	1.00
102_L	176_L	1.031	1.00
390_S	406_S	1.026	1.00
111_F	115_V	1.021	1.00
108_V	111_F	1.019	1.00
65_A	69_A	1.018	1.00
339_L	343_F	1.010	1.00
24_S	146_L	1.009	1.00
41_I	55_G	1.008	1.00
99_M	102_L	1.003	1.00
252_L	256_E	1.003	1.00
34_S	63_G	1.002	1.00
180_P	184_I	1.002	1.00
86_F	130_L	0.999	1.00
351_C	374_F	0.998	1.00
83_L	190_L	0.998	1.00
370_L	374_F	0.996	1.00
367_G	370_L	0.995	1.00
47_F	171_W	0.991	1.00
230_L	237_T	0.989	1.00
168_N	308_I	0.986	1.00
320_M	324_I	0.983	1.00
253_V	266_L	0.981	1.00
281_I	406_S	0.976	1.00
263_I	267_S	0.975	1.00
326_P	330_R	0.974	1.00
86_F	189_C	0.974	1.00
131_L	147_W	0.971	1.00
295_M	372_Q	0.969	1.00
14_G	18_C	0.966	1.00
210_L	214_V	0.963	1.00
313_A	369_I	0.959	1.00
223_M	241_L	0.958	1.00
138_E	142_F	0.956	1.00
88_L	91_T	0.952	1.00
59_I	293_V	0.952	1.00
282_T	409_F	0.947	1.00
343_F	346_L	0.947	1.00
72_V	210_L	0.947	1.00
228_R	231_D	0.945	1.00
191_T	194_K	0.943	1.00
67_A	415_S	0.940	1.00
323_L	326_P	0.939	1.00
265_D	401_N	0.939	1.00
104_T	172_G	0.937	1.00
165_I	169_F	0.937	1.00
226_K	231_D	0.937	1.00
172_G	176_L	0.936	1.00
346_L	349_A	0.935	1.00
417_G	420_L	0.934	1.00
278_I	405_M	0.929	1.00
230_L	235_S	0.928	1.00
344_S	378_A	0.927	1.00
237_T	240_I	0.924	1.00
173_W	176_L	0.922	1.00
90_V	185_V	0.921	1.00
338_R	342_T	0.918	1.00
211_T	215_L	0.918	1.00
359_F	364_D	0.918	1.00
84_R	87_L	0.917	1.00
50_A	55_G	0.915	1.00
37_S	58_V	0.910	1.00
97_S	116_Q	0.910	1.00
127_S	147_W	0.909	1.00
299_L	313_A	0.909	1.00
64_V	415_S	0.905	1.00
36_I	162_G	0.903	1.00
261_N	264_L	0.902	1.00
274_F	402_A	0.901	1.00
111_F	114_V	0.900	1.00
237_T	241_L	0.897	1.00
54_E	107_D	0.896	1.00
82_E	195_G	0.895	1.00
61_S	65_A	0.895	1.00
251_S	254_I	0.890	1.00
14_G	17_W	0.889	1.00
29_M	182_G	0.885	1.00
336_D	339_L	0.883	1.00
424_L	428_R	0.880	1.00
47_F	172_G	0.879	1.00
343_F	347_M	0.877	1.00
78_Q	401_N	0.872	1.00
142_F	330_R	0.871	1.00
271_S	398_K	0.870	1.00
180_P	183_I	0.868	1.00
205_M	210_L	0.867	1.00
300_Q	307_A	0.866	1.00
273_N	393_G	0.864	1.00
340_L	343_F	0.862	1.00
363_I	367_G	0.860	1.00
312_L	316_P	0.857	1.00
249_L	253_V	0.856	1.00
271_S	393_G	0.856	1.00
316_P	320_M	0.850	1.00
209_G	259_S	0.848	1.00
324_I	327_L	0.846	1.00
102_L	112_F	0.846	1.00
324_I	328_I	0.845	1.00
352_Y	375_Q	0.844	1.00
197_E	200_T	0.842	1.00
342_T	346_L	0.842	1.00
23_L	127_S	0.842	1.00
163_G	307_A	0.841	1.00
227_G	230_L	0.841	1.00
271_S	395_P	0.839	1.00
74_G	78_Q	0.838	1.00
429_E	433_H	0.837	1.00
274_F	390_S	0.837	1.00
133_R	399_F	0.836	1.00
44_I	109_L	0.835	1.00
195_G	198_T	0.832	1.00
313_A	365_F	0.830	1.00
80_I	85_L	0.828	1.00
299_L	305_Y	0.827	1.00
272_R	275_T	0.824	1.00
246_V	250_I	0.824	1.00
344_S	382_F	0.823	1.00
354_W	367_G	0.822	1.00
317_I	375_Q	0.820	1.00
90_V	186_L	0.820	1.00
345_F	382_F	0.820	1.00
255_W	258_T	0.819	1.00
101_S	172_G	0.818	1.00
45_S	52_T	0.817	1.00
324_I	380_A	0.816	1.00
332_G	385_P	0.813	1.00
89_S	119_M	0.812	1.00
331_Y	340_L	0.811	1.00
142_F	333_N	0.811	1.00
83_L	195_G	0.805	1.00
58_V	106_L	0.804	1.00
18_C	21_I	0.804	1.00
94_S	98_L	0.804	1.00
240_I	243_V	0.803	1.00
198_T	201_S	0.801	1.00
320_M	377_F	0.799	1.00
98_L	176_L	0.799	1.00
149_M	153_I	0.795	1.00
15_T	18_C	0.794	1.00
82_E	129_S	0.794	1.00
140_R	392_S	0.793	1.00
33_D	178_N	0.790	1.00
299_L	303_M	0.789	1.00
230_L	233_F	0.786	1.00
216_G	219_G	0.784	1.00
66_N	411_T	0.783	1.00
27_T	151_V	0.782	1.00
420_L	423_T	0.780	1.00
91_T	95_L	0.779	1.00
423_T	427_R	0.778	1.00
257_S	266_L	0.776	1.00
78_Q	82_E	0.776	1.00
158_G	162_G	0.771	1.00
242_T	246_V	0.769	1.00
40_A	44_I	0.768	1.00
313_A	316_P	0.766	1.00
387_T	406_S	0.765	1.00
73_T	89_S	0.765	1.00
85_L	122_P	0.765	1.00
166_C	174_I	0.761	1.00
187_T	190_L	0.757	1.00
208_P	211_T	0.756	1.00
15_T	194_K	0.756	1.00
359_F	363_I	0.754	1.00
360_M	363_I	0.753	1.00
208_P	212_L	0.753	1.00
319_I	323_L	0.748	1.00
26_A	123_L	0.745	1.00
238_I	241_L	0.745	1.00
17_W	135_Y	0.744	1.00
22_A	189_C	0.742	1.00
188_L	191_T	0.742	1.00
214_V	218_G	0.742	1.00
93_F	182_G	0.736	1.00
388_T	392_S	0.735	1.00
141_T	329_G	0.734	1.00
32_L	178_N	0.732	1.00
247_I	251_S	0.729	1.00
104_T	112_F	0.728	1.00
200_T	203_V	0.728	1.00
80_I	84_R	0.728	1.00
41_I	59_I	0.727	1.00
176_L	180_P	0.727	1.00
17_W	143_A	0.724	1.00
250_I	253_V	0.724	1.00
280_S	345_F	0.724	1.00
60_T	225_D	0.723	1.00
141_T	145_A	0.723	1.00
219_G	245_S	0.723	1.00
69_A	72_V	0.723	1.00
156_I	318_G	0.719	1.00
30_Q	123_L	0.714	1.00
223_M	227_G	0.713	1.00
32_L	36_I	0.710	1.00
352_Y	356_S	0.710	1.00
43_T	166_C	0.709	1.00
176_L	179_V	0.707	1.00
361_P	364_D	0.707	1.00
369_I	373_F	0.706	1.00
381_C	385_P	0.705	1.00
203_V	261_N	0.705	1.00
131_L	143_A	0.705	1.00
44_I	47_F	0.702	1.00
28_F	157_C	0.700	1.00
324_I	381_C	0.700	1.00
222_I	241_L	0.699	1.00
264_L	405_M	0.696	1.00
20_T	143_A	0.696	1.00
132_L	144_L	0.696	1.00
345_F	349_A	0.695	1.00
270_K	275_T	0.693	1.00
227_G	233_F	0.692	1.00
305_Y	365_F	0.691	1.00
359_F	362_T	0.690	1.00
308_I	312_L	0.688	1.00
228_R	232_W	0.687	1.00
130_L	193_L	0.684	1.00
294_L	422_M	0.684	1.00
278_I	406_S	0.681	1.00
331_Y	334_K	0.680	1.00
96_S	99_M	0.678	1.00
26_A	185_V	0.677	1.00
226_K	233_F	0.677	1.00
151_V	155_P	0.676	1.00
350_V	354_W	0.675	1.00
68_I	218_G	0.673	1.00
196_R	199_E	0.672	1.00
144_L	388_T	0.672	1.00
297_Q	301_E	0.671	1.00
69_A	73_T	0.670	1.00
343_F	381_C	0.670	1.00
100_C	103_S	0.668	1.00
96_S	116_Q	0.668	1.00
190_L	194_K	0.668	1.00
112_F	115_V	0.668	1.00
97_S	179_V	0.666	1.00
152_I	321_P	0.665	1.00
422_M	426_G	0.664	1.00
332_G	336_D	0.664	1.00
236_S	239_I	0.662	1.00
423_T	426_G	0.662	1.00
273_N	277_G	0.661	1.00
129_S	400_A	0.661	1.00
243_V	247_I	0.654	1.00
251_S	255_W	0.653	1.00
391_F	399_F	0.653	1.00
204_K	208_P	0.651	1.00
215_L	218_G	0.649	1.00
413_S	417_G	0.648	1.00
316_P	369_I	0.647	1.00
85_L	88_L	0.647	1.00
167_D	307_A	0.646	1.00
145_A	149_M	0.645	1.00
335_I	339_L	0.642	1.00
298_L	302_T	0.641	1.00
19_V	22_A	0.641	1.00
46_G	49_G	0.639	1.00
342_T	345_F	0.639	1.00
235_S	239_I	0.638	1.00
153_I	157_C	0.637	1.00
221_Q	415_S	0.636	1.00
93_F	119_M	0.636	1.00
219_G	223_M	0.635	1.00
407_N	410_R	0.635	1.00
262_P	266_L	0.634	1.00
100_C	116_Q	0.634	1.00
181_M	184_I	0.634	1.00
335_I	340_L	0.633	1.00
163_G	311_G	0.631	1.00
195_G	199_E	0.630	1.00
48_L	106_L	0.628	1.00
266_L	270_K	0.628	1.00
33_D	113_R	0.628	1.00
33_D	93_F	0.627	1.00
216_G	253_V	0.623	1.00
342_T	349_A	0.623	1.00
128_Q	147_W	0.623	1.00
273_N	276_I	0.621	1.00
317_I	372_Q	0.620	1.00
130_L	134_N	0.620	1.00
144_L	148_S	0.619	1.00
248_S	251_S	0.617	1.00
233_F	237_T	0.617	1.00
217_V	408_F	0.616	1.00
74_G	404_S	0.615	1.00
391_F	403_S	0.614	1.00
65_A	118_L	0.614	1.00
142_F	146_L	0.612	1.00
157_C	160_I	0.612	1.00
288_Y	379_V	0.612	1.00
178_N	182_G	0.612	1.00
350_V	353_Y	0.612	1.00
233_F	236_S	0.609	1.00
327_L	331_Y	0.609	1.00
70_I	407_N	0.609	1.00
293_V	418_T	0.609	1.00
44_I	48_L	0.608	1.00
233_F	239_I	0.607	1.00
165_I	174_I	0.606	1.00
275_T	278_I	0.602	1.00
67_A	412_L	0.601	1.00
347_M	377_F	0.600	1.00
99_M	115_V	0.600	1.00
31_M	154_A	0.599	1.00
55_G	58_V	0.599	1.00
347_M	374_F	0.599	1.00
71_P	213_L	0.596	1.00
132_L	391_F	0.596	1.00
44_I	55_G	0.596	1.00
77_A	129_S	0.594	1.00
246_V	249_L	0.594	1.00
217_V	412_L	0.593	1.00
42_P	46_G	0.590	1.00
32_L	158_G	0.590	1.00
160_I	315_A	0.590	1.00
154_A	158_G	0.590	1.00
355_R	359_F	0.589	1.00
103_S	109_L	0.588	1.00
280_S	386_L	0.587	1.00
230_L	238_I	0.587	1.00
138_E	141_T	0.586	1.00
226_K	238_I	0.585	1.00
205_M	209_G	0.583	1.00
223_M	226_K	0.583	1.00
37_S	44_I	0.581	1.00
312_L	315_A	0.580	1.00
209_G	256_E	0.580	1.00
204_K	207_L	0.576	1.00
135_Y	139_K	0.575	1.00
23_L	130_L	0.574	1.00
215_L	244_V	0.573	1.00
274_F	394_L	0.573	1.00
348_Y	351_C	0.573	1.00
227_G	231_D	0.572	1.00
412_L	416_V	0.572	1.00
235_S	240_I	0.571	1.00
207_L	210_L	0.570	1.00
242_T	245_S	0.570	1.00
128_Q	144_L	0.569	1.00
213_L	217_V	0.569	1.00
360_M	364_D	0.567	1.00
396_D	399_F	0.566	1.00
336_D	340_L	0.560	1.00
38_N	59_I	0.560	1.00
142_F	145_A	0.559	1.00
63_G	415_S	0.558	1.00
162_G	166_C	0.557	1.00
173_W	177_I	0.556	1.00
210_L	263_I	0.556	1.00
327_L	377_F	0.555	1.00
351_C	354_W	0.555	1.00
289_S	292_I	0.553	1.00
83_L	194_K	0.551	1.00
82_E	196_R	0.551	1.00
295_M	299_L	0.551	1.00
82_E	130_L	0.550	1.00
62_F	66_N	0.550	1.00
67_A	411_T	0.549	1.00
74_G	126_L	0.549	1.00
48_L	171_W	0.549	1.00
227_G	238_I	0.548	1.00
419_S	423_T	0.548	1.00
28_F	150_T	0.548	1.00
45_S	50_A	0.547	1.00
282_T	416_V	0.546	1.00
279_V	283_C	0.544	1.00
68_I	210_L	0.543	1.00
30_Q	120_A	0.543	1.00
377_F	381_C	0.542	1.00
405_M	409_F	0.541	1.00
281_I	386_L	0.541	1.00
281_I	410_R	0.539	1.00
262_P	267_S	0.539	1.00
187_T	192_L	0.539	1.00
23_L	134_N	0.537	1.00
45_S	51_S	0.536	1.00
134_N	194_K	0.536	1.00
244_V	251_S	0.533	1.00
166_C	307_A	0.533	1.00
306_N	310_A	0.533	1.00
398_K	401_N	0.533	1.00
208_P	259_S	0.531	1.00
332_G	388_T	0.530	1.00
21_I	25_L	0.529	1.00
74_G	400_A	0.527	1.00
291_A	352_Y	0.526	1.00
354_W	370_L	0.525	1.00
273_N	389_I	0.523	1.00
29_M	181_M	0.523	1.00
235_S	238_I	0.523	1.00
17_W	139_K	0.522	1.00
90_V	182_G	0.522	1.00
245_S	248_S	0.521	1.00
92_F	115_V	0.521	1.00
261_N	265_D	0.521	1.00
359_F	371_P	0.521	1.00
101_S	179_V	0.520	1.00
206_N	255_W	0.519	1.00
213_L	263_I	0.519	1.00
328_I	331_Y	0.517	1.00
373_F	377_F	0.516	1.00
128_Q	403_S	0.515	1.00
225_D	228_R	0.514	1.00
357_V	367_G	0.513	1.00
390_S	393_G	0.513	1.00
17_W	142_F	0.512	1.00
284_A	288_Y	0.512	1.00
133_R	196_R	0.511	1.00
164_Y	312_L	0.510	1.00
245_S	250_I	0.510	1.00
199_E	202_P	0.510	1.00
285_Y	410_R	0.509	1.00
66_N	120_A	0.509	1.00
222_I	230_L	0.508	1.00
152_I	325_S	0.508	1.00
138_E	333_N	0.508	1.00
75_R	261_N	0.507	1.00
96_S	103_S	0.506	1.00
102_L	108_V	0.505	1.00
15_T	192_L	0.505	1.00
229_D	232_W	0.504	1.00
216_G	220_L	0.504	1.00
341_V	385_P	0.504	1.00
63_G	414_G	0.504	1.00
348_Y	352_Y	0.504	1.00
232_W	235_S	0.503	1.00
252_L	264_L	0.501	1.00
96_S	100_C	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1pw4A	1	0.8027	100	0.4	Contact Map
4j05A	3	0.7207	100	0.418	Contact Map
4pypA	1	0.8125	100	0.439	Contact Map
3wdoA	1	0.7695	100	0.44	Contact Map
2gfpA	2	0.7305	100	0.448	Contact Map
3o7qA	1	0.75	100	0.449	Contact Map
4gc0A	1	0.8359	100	0.468	Contact Map
4zw9A	1	0.8516	100	0.471	Contact Map
4ldsA	2	0.8008	100	0.472	Contact Map
4xnjA	1	0.8496	100	0.476	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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