GREMLIN Database
YFJZ - Putative antitoxin YfjZ
UniProt: P52141 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13212
Length: 105 (100)
Sequences: 151 (52)
Seq/√Len: 5.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
59_I73_A5.3340.98
84_T103_T3.3080.80
55_F73_A2.1630.46
29_Y36_I2.1360.45
16_L102_P2.1280.45
45_C54_H2.0950.44
61_S79_Y2.0850.44
50_V54_H2.0510.42
62_M69_N2.0020.41
5_T15_R1.9880.40
24_G40_F1.9460.39
54_H83_F1.8980.38
21_V28_H1.7740.34
9_Q12_I1.7250.32
36_I103_T1.7000.32
7_G14_P1.6430.30
57_S73_A1.5980.29
90_L99_A1.4920.26
29_Y93_C1.4720.26
54_H73_A1.4540.25
50_V56_I1.4500.25
29_Y35_S1.4440.25
51_V80_H1.3750.23
22_Q63_L1.3680.23
89_T96_V1.3340.22
28_H70_P1.3140.22
8_L95_Y1.3020.22
21_V70_P1.2920.21
55_F59_I1.2900.21
25_N29_Y1.2740.21
29_Y43_A1.2710.21
12_I75_C1.2570.21
28_H63_L1.2460.20
56_I83_F1.2450.20
34_A96_V1.2350.20
50_V83_F1.2220.20
23_E28_H1.1950.19
86_E90_L1.1440.18
36_I61_S1.1360.18
47_K55_F1.1150.18
22_Q41_S1.1080.18
29_Y69_N1.0990.17
63_L96_V1.0990.17
4_T98_I1.0690.17
15_R46_P1.0680.17
30_L38_G1.0630.17
9_Q15_R1.0530.16
63_L68_L1.0480.16
78_L102_P1.0440.16
40_F58_Q1.0070.16
56_I77_T1.0040.16
39_K65_T0.9950.15
4_T24_G0.9550.15
55_F81_N0.9530.15
80_H90_L0.9520.15
34_A49_D0.9510.15
29_Y45_C0.9460.15
16_L95_Y0.9450.15
44_E80_H0.9210.14
44_E81_N0.9150.14
26_Q103_T0.9140.14
53_P67_E0.9070.14
47_K83_F0.9050.14
27_L38_G0.8960.14
16_L57_S0.8930.14
72_H79_Y0.8930.14
15_R62_M0.8820.14
70_P83_F0.8750.13
14_P38_G0.8740.13
61_S74_Q0.8720.13
77_T84_T0.8610.13
27_L30_L0.8510.13
37_T96_V0.8500.13
10_R36_I0.8490.13
14_P30_L0.8380.13
36_I56_I0.8370.13
40_F70_P0.8230.13
46_P78_L0.8190.13
7_G38_G0.8080.12
62_M67_E0.8030.12
58_Q67_E0.8010.12
50_V58_Q0.8010.12
10_R75_C0.7990.12
55_F90_L0.7950.12
18_A34_A0.7900.12
36_I45_C0.7850.12
22_Q28_H0.7760.12
71_R77_T0.7670.12
7_G30_L0.7640.12
48_L68_L0.7620.12
78_L100_V0.7580.12
29_Y64_T0.7520.12
49_D93_C0.7500.12
36_I43_A0.7300.11
9_Q39_K0.7280.11
9_Q81_N0.7200.11
90_L98_I0.7190.11
10_R43_A0.7180.11
6_W95_Y0.7060.11
64_T76_V0.7000.11
34_A53_P0.7000.11
49_D82_G0.6980.11
24_G65_T0.6970.11
69_N79_Y0.6900.11
22_Q70_P0.6840.11
73_A87_A0.6810.11
14_P17_G0.6780.11
4_T51_V0.6780.11
38_G101_Y0.6770.11
4_T36_I0.6750.11
44_E55_F0.6720.11
75_C80_H0.6460.10
44_E56_I0.6400.10
30_L101_Y0.6350.10
95_Y102_P0.6330.10
12_I16_L0.6330.10
14_P27_L0.6300.10
7_G27_L0.6280.10
41_S99_A0.6240.10
45_C83_F0.6240.10
44_E102_P0.6230.10
36_I79_Y0.6030.10
56_I80_H0.6010.10
25_N51_V0.6010.10
26_Q96_V0.5970.10
47_K50_V0.5850.10
27_L69_N0.5840.10
44_E69_N0.5810.10
37_T100_V0.5790.10
13_T24_G0.5770.10
46_P64_T0.5770.10
21_V63_L0.5750.09
62_M72_H0.5690.09
22_Q48_L0.5670.09
80_H83_F0.5630.09
41_S49_D0.5630.09
55_F80_H0.5530.09
16_L100_V0.5520.09
9_Q13_T0.5480.09
10_R17_G0.5450.09
25_N69_N0.5350.09
78_L90_L0.5340.09
47_K56_I0.5180.09
8_L16_L0.5160.09
22_Q38_G0.5160.09
33_R92_S0.5140.09
33_R63_L0.5130.09
46_P80_H0.5100.09
17_G71_R0.5040.09
54_H59_I0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ea9A 1 0.981 100 0.048 Contact Map
2inwA 1 1 100 0.054 Contact Map
3h2tA 2 0.2762 21.1 0.952 Contact Map
4jm1A 1 0.3238 16.6 0.954 Contact Map
1dquA 4 0.9048 13.4 0.956 Contact Map
1xv2A 2 0.6381 9.8 0.958 Contact Map
3hvmA 1 0.7333 7.7 0.96 Contact Map
1rybA 1 0.581 7.4 0.96 Contact Map
3neaA 1 0.5905 6.2 0.962 Contact Map
1d3yA 2 0.6571 6.1 0.962 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0053 seconds.