GREMLIN Database
YFJY - UPF0758 protein YfjY
UniProt: P52140 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13211
Length: 160 (152)
Sequences: 4052 (2964)
Seq/√Len: 240.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
152_Y157_H2.8001.00
94_V133_L2.6841.00
67_N71_Q2.6161.00
76_E96_R2.6101.00
107_L140_V2.5121.00
123_K154_F2.4441.00
58_R80_A2.1581.00
49_L108_A2.1461.00
74_A100_F2.0481.00
130_V140_V1.9931.00
120_Q124_T1.9651.00
107_L129_L1.9471.00
83_I103_A1.9371.00
40_T44_A1.8621.00
39_F72_L1.8491.00
68_Q84_S1.7541.00
62_M77_T1.7481.00
65_Y96_R1.7411.00
77_T80_A1.7281.00
127_Q131_Q1.6991.00
123_K159_L1.6791.00
126_T143_H1.6771.00
60_E80_A1.6671.00
60_E77_T1.6331.00
45_A106_I1.6081.00
56_L60_E1.5891.00
43_Q47_D1.5871.00
116_T150_Q1.5741.00
95_K101_N1.5621.00
42_T156_E1.5551.00
79_F86_T1.5471.00
64_L72_L1.5371.00
62_M75_H1.5181.00
24_A28_L1.4841.00
96_R99_Y1.4781.00
131_Q134_Q1.4631.00
93_V129_L1.4591.00
65_Y100_F1.4521.00
53_M56_L1.4011.00
116_T152_Y1.3971.00
61_F88_V1.3941.00
88_V125_I1.3591.00
144_L151_I1.3561.00
70_N104_A1.3491.00
120_Q123_K1.3481.00
94_V136_V1.3391.00
13_L18_Q1.3391.00
69_Q115_D1.3371.00
130_V134_Q1.3371.00
57_E95_K1.3311.00
97_A138_I1.3301.00
52_K75_H1.3141.00
8_P15_L1.3131.00
97_A105_V1.3021.00
96_R100_F1.2871.00
95_K99_Y1.2851.00
46_R151_I1.2761.00
152_Y159_L1.2371.00
61_F140_V1.2271.00
49_L64_L1.2171.00
46_R50_K1.2081.00
65_Y97_A1.1741.00
132_A135_L1.1691.00
53_M62_M1.1291.00
39_F45_A1.1141.00
117_T157_H1.1051.00
154_F159_L1.1001.00
66_L104_A1.0991.00
132_A136_V1.0961.00
61_F86_T1.0891.00
58_R79_F1.0851.00
26_T29_D1.0641.00
64_L75_H1.0631.00
92_E95_K1.0601.00
70_N141_P1.0551.00
105_V133_L1.0551.00
26_T30_R1.0541.00
133_L136_V1.0531.00
56_L77_T1.0491.00
82_S92_E1.0341.00
50_K54_A1.0211.00
48_W75_H1.0111.00
54_A148_G1.0051.00
133_L140_V1.0041.00
82_S89_H1.0021.00
65_Y76_E0.9991.00
145_I152_Y0.9931.00
62_M108_A0.9861.00
63_M107_L0.9831.00
8_P18_Q0.9821.00
131_Q135_L0.9791.00
41_S44_A0.9771.00
83_I91_R0.9761.00
82_S87_E0.9741.00
39_F48_W0.9631.00
13_L17_A0.9491.00
46_R156_E0.9461.00
65_Y102_A0.9461.00
28_L31_H0.9441.00
16_T19_R0.9441.00
43_Q156_E0.9371.00
104_A141_P0.9301.00
17_A23_R0.9251.00
116_T147_G0.9171.00
25_L28_L0.9131.00
127_Q130_V0.9121.00
39_F44_A0.9071.00
20_T24_A0.9051.00
63_M78_L0.8951.00
38_A71_Q0.8750.99
105_V140_V0.8720.99
45_A144_L0.8600.99
25_L31_H0.8570.99
45_A108_A0.8550.99
24_A27_L0.8550.99
50_K148_G0.8540.99
61_F107_L0.8490.99
47_D50_K0.8480.99
58_R92_E0.8450.99
14_P17_A0.8420.99
15_L19_R0.8400.99
118_P152_Y0.8350.99
46_R144_L0.8340.99
76_E100_F0.8330.99
17_A20_T0.8280.99
65_Y78_L0.8240.99
68_Q103_A0.8210.99
74_A96_R0.8170.99
65_Y74_A0.8090.99
18_Q22_K0.8090.99
56_L80_A0.7930.99
52_K77_T0.7920.99
154_F157_H0.7900.99
116_T145_I0.7880.99
61_F125_I0.7870.99
73_I102_A0.7760.99
128_R137_D0.7730.99
54_A147_G0.7680.99
79_F87_E0.7620.98
37_V44_A0.7570.98
121_A124_T0.7560.98
118_P145_I0.7500.98
134_Q139_R0.7500.98
104_A139_R0.7490.98
151_I156_E0.7400.98
128_R131_Q0.7380.98
89_H92_E0.7350.98
123_K127_Q0.7300.98
91_R103_A0.7260.98
24_A31_H0.7210.98
66_L106_I0.7200.98
84_S103_A0.7170.98
58_R76_E0.7140.98
23_R26_T0.7070.98
25_L29_D0.7040.97
49_L75_H0.7020.97
10_T13_L0.6990.97
22_K25_L0.6980.97
93_V107_L0.6880.97
145_I159_L0.6840.97
146_V151_I0.6680.97
50_K149_R0.6630.96
142_D153_S0.6610.96
51_L54_A0.6580.96
88_V93_V0.6540.96
32_L51_L0.6540.96
86_T125_I0.6510.96
78_L93_V0.6510.96
19_R23_R0.6480.96
37_V72_L0.6450.96
16_T20_T0.6440.96
18_Q21_V0.6440.96
124_T127_Q0.6400.96
20_T23_R0.6270.95
53_M146_V0.6250.95
42_T46_R0.6230.95
66_L70_N0.6200.95
133_L138_I0.6200.95
38_A72_L0.6150.94
12_V17_A0.6140.94
8_P22_K0.6120.94
129_L140_V0.6050.94
29_D33_R0.5960.94
147_G150_Q0.5950.93
124_T128_R0.5890.93
52_K62_M0.5880.93
44_A47_D0.5860.93
13_L25_L0.5800.93
57_E101_N0.5790.93
23_R27_L0.5780.92
90_P129_L0.5780.92
39_F64_L0.5780.92
20_T27_L0.5750.92
65_Y105_V0.5750.92
23_R28_L0.5730.92
134_Q137_D0.5700.92
128_R132_A0.5630.91
83_I101_N0.5610.91
94_V140_V0.5600.91
98_L102_A0.5560.91
108_A144_L0.5510.91
33_R52_K0.5510.91
53_M108_A0.5410.90
50_K146_V0.5400.90
90_P94_V0.5390.90
42_T45_A0.5370.89
79_F125_I0.5350.89
73_I100_F0.5350.89
150_Q157_H0.5270.89
17_A30_R0.5250.88
98_L138_I0.5240.88
57_E99_Y0.5240.88
37_V71_Q0.5240.88
39_F70_N0.5220.88
98_L132_A0.5220.88
16_T23_R0.5200.88
20_T29_D0.5200.88
124_T131_Q0.5160.88
123_K152_Y0.5160.88
115_D118_P0.5160.88
36_G71_Q0.5130.87
44_A72_L0.5110.87
95_K98_L0.5110.87
17_A27_L0.5110.87
8_P11_P0.5050.86
68_Q83_I0.5040.86
70_N103_A0.5010.86
17_A21_V0.5000.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2qlcA 1 0.7875 100 0.213 Contact Map
1oi0A 1 0.625 86.2 0.903 Contact Map
2kcqA 1 0.7063 85.1 0.904 Contact Map
2kksA 1 0.7125 84.4 0.905 Contact Map
1dgsA 1 0.2875 82.5 0.907 Contact Map
2owoA 1 0.2875 73.1 0.915 Contact Map
3wu2U 1 0.4375 68.6 0.917 Contact Map
2znrA 1 0.8187 66.8 0.919 Contact Map
2a1jB 2 0.35 65.6 0.919 Contact Map
1kftA 1 0.1688 65.3 0.919 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0067 seconds.