GREMLIN Database
YFJP - Uncharacterized protein YfjP
UniProt: P52131 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13202
Length: 287 (227)
Sequences: 7660 (5641)
Seq/√Len: 374.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
191_P209_R3.2691.00
55_A203_L3.0611.00
119_L151_V2.9801.00
209_R212_K2.8641.00
180_C183_H2.8061.00
55_A200_Q2.6851.00
193_C209_R2.3741.00
243_F247_V2.3531.00
124_A152_I2.3011.00
41_I53_C2.2921.00
130_A134_H2.1681.00
40_G115_L2.1491.00
202_G205_V2.1081.00
44_K132_D2.1001.00
209_R213_C2.0841.00
119_L210_M2.0811.00
101_D104_Y2.0461.00
181_L185_L2.0261.00
153_S197_V1.9711.00
122_I150_F1.9601.00
213_C217_E1.9211.00
237_E240_R1.8561.00
151_V195_V1.8271.00
233_T237_E1.7731.00
52_L121_L1.7681.00
154_Q157_K1.7421.00
173_Q176_S1.7411.00
76_R87_T1.7271.00
103_E106_A1.7051.00
259_L262_A1.6921.00
51_S197_V1.6911.00
56_L203_L1.6741.00
241_D245_E1.6591.00
78_R85_F1.6521.00
149_L209_R1.6431.00
121_L153_S1.6341.00
133_E137_R1.6291.00
41_I119_L1.6281.00
84_H211_I1.6161.00
80_Q85_F1.5961.00
155_S194_A1.5731.00
181_L184_E1.5661.00
128_A132_D1.5471.00
208_E212_K1.5251.00
152_I194_A1.4731.00
123_K153_S1.4661.00
250_I254_V1.4651.00
38_V87_T1.4651.00
228_H232_T1.4561.00
265_R269_Q1.4411.00
39_I86_M1.4091.00
136_Y140_I1.3991.00
151_V206_M1.3951.00
119_L206_M1.3931.00
236_R240_R1.3871.00
251_L255_S1.3601.00
249_A252_D1.3571.00
244_G248_G1.3501.00
206_M210_M1.3491.00
239_A243_F1.3361.00
250_I253_T1.3201.00
234_V238_Q1.3161.00
235_A238_Q1.3151.00
78_R87_T1.3131.00
241_D244_G1.2861.00
137_R140_I1.2821.00
260_I263_P1.2771.00
51_S64_V1.2771.00
264_V267_I1.2661.00
125_D157_K1.2631.00
149_L193_C1.2631.00
52_L56_L1.2621.00
109_R138_Q1.2551.00
247_V251_L1.2551.00
247_V250_I1.2501.00
152_I192_V1.2501.00
204_R208_E1.2451.00
252_D255_S1.2401.00
44_K131_T1.2361.00
103_E107_L1.2301.00
232_T235_A1.2231.00
130_A133_E1.2021.00
262_A266_T1.1991.00
44_K129_L1.1881.00
251_L257_F1.1861.00
199_L202_G1.1861.00
182_L186_F1.1851.00
56_L207_A1.1771.00
244_G247_V1.1761.00
123_K126_D1.1681.00
219_S223_V1.1651.00
260_I264_V1.1591.00
234_V239_A1.1591.00
266_T269_Q1.1381.00
259_L263_P1.1311.00
120_W136_Y1.1231.00
261_P265_R1.1221.00
235_A239_A1.1221.00
247_V254_V1.1191.00
176_S179_I1.1181.00
128_A133_E1.1181.00
230_F234_V1.1131.00
239_A244_G1.1111.00
129_L132_D1.1091.00
180_C184_E1.1061.00
134_H138_Q1.1051.00
249_A253_T1.0991.00
253_T257_F1.0971.00
243_F246_T1.0931.00
240_R244_G1.0921.00
51_S195_V1.0911.00
74_P77_F1.0861.00
232_T236_R1.0831.00
205_V208_E1.0751.00
246_T250_I1.0741.00
222_V225_L1.0731.00
243_F255_S1.0711.00
174_N177_R1.0691.00
56_L79_L1.0671.00
105_A108_Y1.0671.00
232_T239_A1.0601.00
230_F236_R1.0591.00
233_T236_R1.0571.00
131_T134_H1.0471.00
84_H215_P1.0421.00
207_A211_I1.0401.00
133_E178_K1.0301.00
263_P267_I1.0281.00
183_H186_F1.0261.00
241_D247_V1.0221.00
123_K154_Q1.0161.00
258_P262_A1.0161.00
177_R180_C1.0051.00
52_L195_V1.0001.00
53_C88_I0.9931.00
253_T256_T0.9901.00
117_L149_L0.9891.00
156_D196_S0.9891.00
242_D245_E0.9861.00
264_V268_I0.9831.00
238_Q241_D0.9811.00
224_A227_Q0.9771.00
230_F237_E0.9771.00
207_A210_M0.9721.00
229_P233_T0.9711.00
236_R239_A0.9671.00
242_D246_T0.9661.00
252_D256_T0.9601.00
242_D247_V0.9501.00
224_A228_H0.9441.00
106_A110_E0.9391.00
173_Q177_R0.9311.00
261_P264_V0.9201.00
259_L264_V0.9161.00
155_S201_W0.9121.00
203_L207_A0.9071.00
155_S158_A0.9031.00
238_Q242_D0.8991.00
99_V102_T0.8951.00
249_A254_V0.8931.00
260_I267_I0.8911.00
107_L111_Q0.8911.00
248_G252_D0.8851.00
260_I268_I0.8851.00
81_I211_I0.8841.00
247_V252_D0.8811.00
244_G253_T0.8791.00
240_R243_F0.8781.00
231_R234_V0.8751.00
191_P213_C0.8691.00
150_F189_V0.8571.00
256_T259_L0.8501.00
176_S182_L0.8491.00
262_A269_Q0.8481.00
196_S199_L0.8451.00
117_L213_C0.8391.00
108_Y112_L0.8391.00
212_K216_R0.8381.00
159_E194_A0.8201.00
52_L206_M0.8121.00
231_R235_A0.8121.00
39_I117_L0.8111.00
250_I255_S0.8051.00
174_N178_K0.8051.00
139_V148_M0.8021.00
261_P268_I0.8001.00
178_K181_L0.7971.00
52_L203_L0.7911.00
232_T243_F0.7871.00
79_L207_A0.7821.00
72_R77_F0.7781.00
178_K182_L0.7761.00
135_F138_Q0.7741.00
175_I179_I0.7661.00
200_Q203_L0.7661.00
117_L210_M0.7651.00
89_V111_Q0.7641.00
239_A242_D0.7621.00
55_A197_V0.7621.00
231_R242_D0.7601.00
235_A240_R0.7561.00
193_C202_G0.7541.00
228_H231_R0.7541.00
239_A257_F0.7531.00
100_R104_Y0.7511.00
258_P263_P0.7441.00
230_F233_T0.7401.00
231_R236_R0.7391.00
133_E185_L0.7381.00
195_V198_R0.7331.00
263_P269_Q0.7311.00
124_A158_A0.7281.00
100_R103_E0.7281.00
91_L108_Y0.7261.00
179_I183_H0.7261.00
244_G250_I0.7261.00
261_P267_I0.7251.00
107_L110_E0.7181.00
150_F190_H0.7161.00
61_V77_F0.7151.00
119_L149_L0.7141.00
179_I182_L0.7141.00
40_G91_L0.7121.00
62_S65_S0.7101.00
83_E211_I0.7091.00
38_V116_D0.7091.00
244_G251_L0.7060.99
263_P266_T0.7040.99
89_V114_R0.7000.99
262_A265_R0.7000.99
231_R238_Q0.6980.99
53_C62_S0.6980.99
57_F61_V0.6930.99
82_G211_I0.6910.99
234_V240_R0.6880.99
205_V209_R0.6860.99
97_S101_D0.6860.99
259_L266_T0.6850.99
44_K47_A0.6830.99
176_S194_A0.6790.99
246_T249_A0.6750.99
258_P267_I0.6730.99
230_F239_A0.6720.99
124_A155_S0.6710.99
211_I215_P0.6700.99
151_V193_C0.6690.99
228_H236_R0.6670.99
40_G118_I0.6640.99
99_V104_Y0.6590.99
265_R268_I0.6590.99
237_E241_D0.6590.99
179_I186_F0.6580.99
183_H192_V0.6500.99
236_R243_F0.6490.99
70_C75_L0.6490.99
243_F251_L0.6480.99
45_T68_A0.6460.99
240_R247_V0.6440.99
90_D93_G0.6410.99
136_Y139_V0.6380.99
254_V259_L0.6360.99
236_R244_G0.6360.99
110_E114_R0.6360.99
237_E250_I0.6340.99
226_L230_F0.6330.99
50_S54_N0.6250.99
241_D250_I0.6240.99
255_S259_L0.6220.99
80_Q83_E0.6190.99
239_A246_T0.6130.99
191_P194_A0.6080.98
134_H137_R0.6060.98
62_S77_F0.6060.98
201_W205_V0.6050.98
149_L213_C0.6030.98
53_C77_F0.6020.98
249_A257_F0.6020.98
247_V256_T0.6010.98
233_T246_T0.5990.98
259_L265_R0.5990.98
135_F139_V0.5980.98
229_P232_T0.5970.98
125_D152_I0.5970.98
150_F192_V0.5940.98
233_T239_A0.5940.98
255_S265_R0.5930.98
37_P214_L0.5900.98
149_L210_M0.5890.98
50_S62_S0.5880.98
63_P70_C0.5870.98
81_I207_A0.5860.98
177_R181_L0.5850.98
186_F189_V0.5770.98
55_A195_V0.5760.98
120_W150_F0.5760.98
145_R153_S0.5690.98
126_D129_L0.5660.98
243_F257_F0.5610.97
204_R207_A0.5600.97
123_K157_K0.5580.97
234_V237_E0.5580.97
264_V269_Q0.5570.97
182_L185_L0.5550.97
120_W148_M0.5550.97
60_E63_P0.5500.97
53_C57_F0.5480.97
257_F260_I0.5480.97
261_P266_T0.5480.97
104_Y107_L0.5460.97
249_A256_T0.5450.97
249_A255_S0.5450.97
63_P75_L0.5450.97
213_C216_R0.5420.97
71_T76_R0.5390.97
94_V97_S0.5360.97
75_L79_L0.5340.97
81_I84_H0.5340.97
63_P69_A0.5320.97
76_R79_L0.5320.97
176_S180_C0.5290.96
248_G251_L0.5280.96
255_S258_P0.5270.96
244_G249_A0.5270.96
257_F262_A0.5250.96
137_R143_A0.5250.96
256_T262_A0.5250.96
244_G256_T0.5230.96
258_P268_I0.5200.96
151_V194_A0.5180.96
51_S198_R0.5160.96
47_A123_K0.5140.96
75_L78_R0.5140.96
233_T243_F0.5090.96
247_V253_T0.5080.95
225_L229_P0.5080.95
250_I256_T0.5030.95
57_F77_F0.5020.95
250_I257_F0.5020.95
236_R257_F0.5000.95
112_L118_I0.5000.95
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ievA 1 0.8432 100 0.461 Contact Map
2j69A 1 0.9721 100 0.462 Contact Map
1xzpA 4 0.9233 100 0.474 Contact Map
3gehA 2 0.8571 100 0.476 Contact Map
1egaA 2 0.8397 100 0.481 Contact Map
3geeA 2 0.7979 100 0.482 Contact Map
1wf3A 1 0.8397 100 0.484 Contact Map
4aurA 1 0.9826 100 0.484 Contact Map
1mkyA 1 0.8746 100 0.489 Contact Map
4dcuA 1 0.9129 100 0.493 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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