GREMLIN Database
YFJJ - Uncharacterized protein YfjJ
UniProt: P52125 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13196
Length: 208 (188)
Sequences: 314 (233)
Seq/√Len: 17.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
76_D121_Y5.9441.00
34_I113_I4.1461.00
72_K140_T3.7981.00
34_I181_L3.6891.00
160_P184_R3.4180.99
68_A72_K3.4120.99
72_K144_S3.1590.99
31_N119_D2.9810.99
135_R159_Y2.8810.98
113_I185_V2.7040.97
165_Y184_R2.6770.97
15_R186_D2.5110.96
134_L137_M2.4500.95
29_H32_S2.3980.94
22_I181_L2.3200.93
133_T137_M2.2870.93
113_I181_L2.2590.92
69_L114_L2.1860.91
41_D61_A2.1770.91
143_Y153_S2.1490.90
11_V191_V2.0300.87
37_V114_L2.0180.87
102_Y108_R2.0120.87
28_E95_R2.0040.87
160_P165_Y1.9580.85
25_S95_R1.9170.84
162_N184_R1.9060.84
160_P163_G1.8290.81
22_I34_I1.7270.77
103_T193_T1.7150.77
99_V188_M1.6980.76
15_R182_M1.6650.74
183_N186_D1.6470.74
35_L114_L1.6290.73
73_L92_S1.6200.72
182_M186_D1.5200.67
77_K120_A1.4990.66
33_M116_F1.4670.65
88_D134_L1.4440.63
30_L119_D1.4170.62
73_L94_L1.3990.61
201_R207_R1.3940.60
39_L65_F1.3770.59
187_Y194_K1.3360.57
102_Y105_N1.3330.57
18_I189_T1.3280.57
29_H35_L1.3270.57
138_I159_Y1.3230.56
98_W204_G1.3010.55
66_T96_Y1.2990.55
65_F117_N1.2990.55
100_R198_D1.2890.54
89_S120_A1.2600.53
90_R120_A1.2580.52
63_S67_S1.2570.52
37_V112_L1.2400.51
32_S95_R1.2260.51
10_H186_D1.2170.50
10_H144_S1.2020.49
63_S72_K1.1960.49
177_T189_T1.1750.48
102_Y106_R1.1730.47
35_L138_I1.1640.47
18_I97_A1.1550.46
103_T106_R1.1520.46
102_Y107_K1.1480.46
15_R183_N1.1420.46
29_H93_T1.1250.45
99_V203_F1.1070.43
61_A73_L1.1060.43
71_A75_H1.1050.43
114_L138_I1.1030.43
167_L174_F1.0970.43
173_N177_T1.0890.42
12_S84_K1.0860.42
71_A116_F1.0640.41
34_I160_P1.0520.40
64_R145_A1.0500.40
187_Y190_K1.0470.40
10_H95_R1.0460.40
118_Q166_L1.0310.39
73_L77_K1.0200.38
148_I153_S1.0080.38
114_L167_L0.9980.37
109_H187_Y0.9960.37
11_V201_R0.9710.36
17_R203_F0.9660.35
101_E187_Y0.9640.35
40_H100_R0.9630.35
68_A141_A0.9520.35
11_V196_V0.9510.35
127_Y135_R0.9370.34
29_H120_A0.9370.34
61_A133_T0.9370.34
67_S70_K0.9360.34
32_S82_Q0.9330.34
64_R144_S0.9270.33
71_A141_A0.9190.33
29_H188_M0.9150.33
92_S168_N0.9110.33
74_K166_L0.9100.32
124_L127_Y0.9100.32
33_M124_L0.9070.32
29_H95_R0.8990.32
41_D155_K0.8960.32
58_D205_C0.8960.32
9_S186_D0.8920.32
135_R139_T0.8860.31
167_L181_L0.8840.31
21_V25_S0.8750.31
82_Q201_R0.8710.30
69_L138_I0.8700.30
59_S174_F0.8670.30
118_Q122_Y0.8660.30
62_I121_Y0.8660.30
69_L94_L0.8650.30
17_R20_Q0.8570.30
41_D166_L0.8530.30
148_I207_R0.8520.29
156_L201_R0.8410.29
10_H72_K0.8370.29
70_K199_G0.8360.29
143_Y182_M0.8340.29
87_P207_R0.8310.28
190_K206_S0.8300.28
162_N165_Y0.8170.28
143_Y186_D0.8130.28
14_Y196_V0.8090.27
69_L72_K0.8040.27
29_H92_S0.8020.27
182_M207_R0.8000.27
22_I159_Y0.7990.27
18_I203_F0.7950.27
43_I107_K0.7870.26
127_Y153_S0.7800.26
187_Y206_S0.7770.26
28_E93_T0.7760.26
37_V116_F0.7740.26
40_H46_E0.7730.26
185_V188_M0.7680.25
8_G22_I0.7660.25
82_Q168_N0.7650.25
119_D157_V0.7630.25
29_H136_T0.7540.25
111_H187_Y0.7520.25
165_Y169_R0.7510.25
67_S86_W0.7410.24
83_R112_L0.7370.24
61_A158_N0.7370.24
77_K89_S0.7350.24
68_A144_S0.7290.24
83_R86_W0.7270.24
101_E109_H0.7260.24
197_G200_D0.7250.24
181_L192_R0.7240.24
153_S197_G0.7210.23
97_A160_P0.7190.23
77_K110_Y0.7130.23
63_S123_H0.7100.23
23_D147_G0.7090.23
151_D168_N0.7050.23
94_L164_K0.7040.23
138_I148_I0.7020.23
14_Y65_F0.7000.23
71_A115_C0.7000.23
76_D133_T0.6970.22
131_R167_L0.6960.22
22_I202_N0.6930.22
105_N116_F0.6870.22
99_V113_I0.6860.22
76_D82_Q0.6820.22
40_H158_N0.6800.22
30_L95_R0.6790.22
36_R165_Y0.6790.22
130_N176_Q0.6720.21
58_D61_A0.6720.21
59_S189_T0.6720.21
181_L184_R0.6700.21
124_L164_K0.6670.21
37_V176_Q0.6650.21
71_A144_S0.6600.21
64_R68_A0.6570.21
11_V67_S0.6510.21
120_A163_G0.6480.20
22_I112_L0.6480.20
77_K92_S0.6480.20
26_L140_T0.6470.20
158_N168_N0.6430.20
126_D133_T0.6410.20
39_L109_H0.6400.20
20_Q67_S0.6370.20
190_K194_K0.6360.20
120_A188_M0.6330.20
158_N185_V0.6310.20
194_K206_S0.6300.20
22_I195_I0.6290.20
90_R201_R0.6280.20
22_I185_V0.6270.20
103_T192_R0.6260.20
91_H138_I0.6250.20
12_S15_R0.6230.19
8_G196_V0.6220.19
114_L205_C0.6200.19
121_Y163_G0.6200.19
92_S120_A0.6200.19
18_I185_V0.6190.19
61_A116_F0.6190.19
86_W201_R0.6150.19
64_R98_W0.6140.19
66_T94_L0.6110.19
30_L66_T0.6110.19
94_L126_D0.6080.19
25_S30_L0.6070.19
26_L35_L0.6060.19
146_L165_Y0.6050.19
7_F178_Y0.6020.19
185_V189_T0.5990.19
126_D137_M0.5990.19
143_Y150_I0.5970.19
149_P152_S0.5960.18
141_A199_G0.5950.18
21_V32_S0.5940.18
8_G114_L0.5920.18
114_L134_L0.5910.18
64_R70_K0.5900.18
34_I185_V0.5890.18
9_S15_R0.5800.18
94_L189_T0.5790.18
97_A100_R0.5780.18
165_Y181_L0.5760.18
82_Q86_W0.5750.18
71_A207_R0.5740.18
144_S184_R0.5710.18
72_K137_M0.5710.18
14_Y121_Y0.5680.17
122_Y126_D0.5680.17
139_T143_Y0.5630.17
108_R200_D0.5610.17
10_H183_N0.5610.17
59_S100_R0.5600.17
115_C180_D0.5590.17
171_R180_D0.5540.17
124_L196_V0.5520.17
109_H194_K0.5450.17
66_T74_K0.5450.17
40_H156_L0.5440.17
99_V104_K0.5390.17
198_D205_C0.5390.17
19_K33_M0.5350.16
68_A73_L0.5320.16
128_D158_N0.5310.16
12_S181_L0.5310.16
65_F141_A0.5300.16
14_Y25_S0.5290.16
27_N63_S0.5270.16
68_A76_D0.5260.16
58_D198_D0.5240.16
75_H116_F0.5240.16
99_V105_N0.5240.16
9_S32_S0.5230.16
86_W89_S0.5220.16
125_G141_A0.5210.16
104_K180_D0.5190.16
16_D84_K0.5180.16
70_K159_Y0.5170.16
133_T186_D0.5170.16
72_K198_D0.5160.16
186_D189_T0.5130.16
20_Q196_V0.5120.16
108_R198_D0.5110.16
135_R201_R0.5110.16
117_N145_A0.5110.16
67_S72_K0.5100.16
18_I134_L0.5090.16
127_Y159_Y0.5090.16
42_P190_K0.5070.15
168_N171_R0.5070.15
124_L143_Y0.5060.15
103_T207_R0.5040.15
63_S167_L0.5030.15
159_Y192_R0.5020.15
16_D19_K0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3v2cY 1 0.3798 14.8 0.964 Contact Map
2ixsA 1 0.3702 9.2 0.967 Contact Map
2pfmA 4 0.4231 8.5 0.967 Contact Map
1tueA 1 0.3413 8 0.968 Contact Map
1ug8A 1 0.3606 6.9 0.969 Contact Map
2mrnA 2 0.3221 6.4 0.969 Contact Map
3j0aA 1 0.3894 6.2 0.969 Contact Map
3kz5E 2 0.1394 5.9 0.97 Contact Map
2hzdA 1 0.3942 5.4 0.97 Contact Map
4idoA 2 0.476 4.2 0.972 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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