GREMLIN Database
YFJI - Uncharacterized protein YfjI
UniProt: P52124 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13195
Length: 469 (418)
Sequences: 875 (760)
Seq/√Len: 37.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
73_G341_S7.0841.00
155_K211_E5.1031.00
52_V364_I4.5191.00
308_F369_V4.1251.00
160_D212_R4.0471.00
62_V352_A3.9941.00
44_L178_G3.6361.00
203_W346_N3.5381.00
32_G378_W3.5191.00
36_A379_Y3.4171.00
184_A229_L3.3901.00
112_F148_P3.2111.00
227_L256_C3.1381.00
92_E221_R3.0791.00
71_E337_K2.9671.00
248_K338_D2.8361.00
382_E385_R2.7721.00
196_L250_I2.7431.00
37_S80_D2.5991.00
97_K101_D2.5661.00
399_E437_K2.5481.00
309_S363_D2.5331.00
43_S226_T2.5271.00
105_W148_P2.5111.00
421_K439_N2.4911.00
67_M256_C2.4541.00
190_G193_L2.4361.00
60_G345_E2.3191.00
369_V373_V2.2730.99
422_N426_Q2.2670.99
420_K423_I2.2630.99
164_A212_R2.2610.99
33_L70_A2.2580.99
315_H370_K2.2410.99
266_G324_E2.2300.99
105_W151_P2.1830.99
358_S371_A2.1720.99
423_I426_Q2.1520.99
165_A213_K2.1490.99
104_A108_D2.1490.99
42_I357_F2.1320.99
38_A83_L2.1130.99
203_W345_E2.1100.99
185_G197_P2.0920.99
347_M376_V1.9600.98
12_F20_I1.9540.98
109_E147_N1.9530.98
106_R147_N1.9400.98
424_I438_A1.9340.98
7_F35_A1.9300.98
366_V370_K1.9140.98
322_Q377_A1.8820.98
168_A213_K1.8720.98
400_A441_L1.8560.98
161_A166_I1.8350.97
158_F169_H1.8290.97
286_R289_E1.8210.97
308_F348_A1.8180.97
40_G66_L1.8010.97
158_F177_V1.8010.97
311_E366_V1.8010.97
358_S368_A1.7880.97
315_H373_V1.7790.97
109_E113_N1.7670.97
23_V38_A1.7480.97
355_H368_A1.7440.97
234_N249_G1.7300.96
29_A34_I1.7250.96
93_D288_M1.7030.96
343_M380_I1.6840.96
105_W109_E1.6830.96
343_M376_V1.6740.96
403_L441_L1.6610.95
63_S349_R1.6610.95
32_G382_E1.6240.95
181_S201_K1.6030.94
408_K411_C1.6020.94
77_S206_S1.5960.94
169_H177_V1.5860.94
41_V83_L1.5830.94
315_H366_V1.5680.94
8_P11_A1.5670.94
54_R348_A1.5570.93
182_D206_S1.5450.93
333_L340_A1.5440.93
421_K438_A1.5290.93
155_K209_T1.5240.93
315_H369_V1.5210.93
280_L284_H1.5160.93
378_W382_E1.5070.92
257_L346_N1.5050.92
74_E263_S1.5040.92
319_F373_V1.4990.92
28_Q324_E1.4920.92
75_R320_Y1.4900.92
7_F379_Y1.4880.92
265_Q268_R1.4860.92
83_L283_F1.4840.92
27_T75_R1.4730.91
435_R439_N1.4720.91
354_L375_I1.4690.91
39_L354_L1.4680.91
94_L156_F1.4630.91
163_P195_E1.4610.91
400_A445_L1.4460.91
42_I353_L1.4380.90
268_R324_E1.4360.90
67_M184_A1.4050.89
326_E332_L1.4020.89
422_N425_L1.3970.89
162_T212_R1.3900.89
50_I356_Y1.3890.89
263_S266_G1.3870.89
267_N328_R1.3690.88
75_R78_T1.3680.88
257_L261_P1.3660.88
232_Q312_A1.3510.87
72_S254_A1.3270.86
306_L352_A1.3000.85
61_P349_R1.2990.85
347_M369_V1.2900.85
105_W150_A1.2790.84
160_D210_V1.2760.84
98_Y151_P1.2740.84
102_L106_R1.2670.84
40_G228_S1.2600.83
200_N250_I1.2570.83
85_K89_Q1.2440.83
70_A230_M1.2310.82
351_A372_A1.2300.82
429_P433_R1.2220.81
200_N342_K1.2170.81
208_F306_L1.1970.80
263_S268_R1.1880.80
22_E276_S1.1830.79
98_Y102_L1.1810.79
284_H288_M1.1780.79
159_N201_K1.1540.78
421_K425_L1.1540.78
351_A369_V1.1390.77
261_P385_R1.1280.76
91_E155_K1.1190.75
319_F347_M1.0980.74
404_Y407_I1.0950.74
198_F208_F1.0930.74
280_L286_R1.0890.73
41_V87_L1.0890.73
10_D418_C1.0860.73
290_I293_E1.0850.73
306_L355_H1.0840.73
290_I438_A1.0790.73
325_S370_K1.0750.72
45_A226_T1.0730.72
10_D374_E1.0710.72
375_I379_Y1.0660.72
419_I442_I1.0650.72
202_M223_A1.0600.71
428_G433_R1.0590.71
70_A74_E1.0520.71
65_F364_I1.0500.70
408_K412_T1.0490.70
345_E349_R1.0480.70
196_L200_N1.0410.70
96_E99_T1.0370.70
43_S353_L1.0350.69
55_L58_L1.0330.69
236_F386_L1.0280.69
205_G342_K1.0250.69
29_A79_V1.0220.68
47_Q63_S1.0220.68
164_A195_E1.0220.68
60_G349_R1.0180.68
113_N117_K1.0160.68
37_S83_L1.0160.68
441_L445_L1.0150.68
35_A375_I1.0110.68
319_F377_A1.0070.67
75_R266_G1.0070.67
90_L291_V1.0060.67
160_D364_I1.0060.67
203_W338_D1.0050.67
364_I420_K1.0050.67
232_Q342_K0.9990.67
78_T342_K0.9950.66
314_R318_E0.9940.66
203_W210_V0.9910.66
183_E342_K0.9900.66
7_F354_L0.9800.65
446_I451_I0.9770.65
71_E334_Y0.9750.65
350_L354_L0.9740.65
93_D97_K0.9690.64
307_R350_L0.9660.64
272_N364_I0.9650.64
400_A444_I0.9630.64
65_F250_I0.9620.64
8_P349_R0.9590.63
76_K251_G0.9590.63
32_G261_P0.9570.63
100_H103_T0.9570.63
148_P151_P0.9500.63
76_K255_R0.9420.62
41_V45_A0.9410.62
343_M346_N0.9410.62
173_H204_D0.9370.62
30_P268_R0.9350.61
257_L379_Y0.9310.61
112_F147_N0.9260.61
187_I227_L0.9250.61
77_S182_D0.9200.60
342_K345_E0.9170.60
80_D228_S0.9150.60
161_A165_A0.9120.59
75_R324_E0.9120.59
50_I62_V0.9110.59
8_P257_L0.9090.59
202_M225_I0.9090.59
20_I386_L0.9050.59
58_L200_N0.9040.59
437_K441_L0.9040.59
52_V62_V0.9020.59
74_E264_T0.9010.59
168_A215_E0.9000.58
63_S224_R0.8990.58
212_R216_P0.8990.58
167_K198_F0.8970.58
16_I357_F0.8960.58
292_N424_I0.8950.58
181_S186_I0.8950.58
316_W348_A0.8910.58
90_L156_F0.8910.58
167_K220_I0.8870.57
147_N152_V0.8870.57
350_L375_I0.8850.57
382_E419_I0.8820.57
281_P405_C0.8770.56
65_F199_I0.8760.56
425_L428_G0.8740.56
89_Q288_M0.8740.56
34_I63_S0.8730.56
106_R315_H0.8700.56
86_P283_F0.8700.56
176_S184_A0.8620.55
19_A283_F0.8620.55
90_L292_N0.8590.55
425_L438_A0.8560.55
366_V369_V0.8550.55
194_N239_Y0.8520.54
424_I435_R0.8520.54
259_C379_Y0.8520.54
372_A376_V0.8500.54
206_S223_A0.8480.54
184_A231_V0.8440.54
30_P324_E0.8420.53
52_V352_A0.8400.53
20_I31_Q0.8400.53
182_D188_F0.8390.53
72_S341_S0.8390.53
164_A186_I0.8380.53
74_E324_E0.8380.53
17_R21_Y0.8360.53
404_Y450_K0.8350.53
164_A191_Y0.8310.52
434_N437_K0.8310.52
266_G340_A0.8290.52
158_F166_I0.8280.52
283_F286_R0.8260.52
183_E251_G0.8230.52
116_K148_P0.8220.52
189_N192_T0.8210.52
395_L399_E0.8200.51
327_M341_S0.8200.51
346_N379_Y0.8190.51
279_H283_F0.8190.51
311_E370_K0.8180.51
170_L233_P0.8170.51
43_S340_A0.8170.51
90_L94_L0.8160.51
184_A198_F0.8150.51
444_I448_Q0.8140.51
298_I318_E0.8130.51
38_A354_L0.8100.51
344_A364_I0.8090.50
379_Y382_E0.8040.50
180_M228_S0.8040.50
28_Q43_S0.8040.50
72_S204_D0.8030.50
446_I453_I0.8010.50
343_M386_L0.8010.50
441_L444_I0.7980.49
254_A382_E0.7980.49
16_I42_I0.7970.49
261_P378_W0.7970.49
200_N232_Q0.7930.49
150_A227_L0.7910.49
47_Q78_T0.7900.49
266_G341_S0.7890.49
324_E341_S0.7880.49
432_F441_L0.7880.49
186_I197_P0.7850.48
47_Q352_A0.7810.48
73_G375_I0.7810.48
108_D367_T0.7810.48
310_A363_D0.7800.48
114_I118_A0.7800.48
159_N305_C0.7790.48
161_A186_I0.7780.48
251_G255_R0.7760.48
100_H104_A0.7760.48
36_A250_I0.7740.47
43_S63_S0.7710.47
259_C332_L0.7700.47
108_D271_S0.7700.47
164_A232_Q0.7690.47
86_P342_K0.7680.47
28_Q268_R0.7670.47
48_N175_R0.7660.47
85_K289_E0.7630.46
406_W427_F0.7610.46
261_P266_G0.7610.46
72_S291_V0.7600.46
169_H211_E0.7600.46
225_I247_A0.7560.46
75_R341_S0.7540.46
111_I451_I0.7540.46
143_L203_W0.7540.46
424_I428_G0.7510.45
336_F387_F0.7510.45
310_A314_R0.7480.45
344_A348_A0.7480.45
163_P198_F0.7480.45
350_L376_V0.7470.45
159_N179_I0.7460.45
27_T79_V0.7450.45
425_L435_R0.7450.45
99_T108_D0.7440.45
92_E96_E0.7420.45
165_A212_R0.7400.44
424_I437_K0.7400.44
86_P364_I0.7400.44
354_L372_A0.7400.44
293_E307_R0.7390.44
185_G200_N0.7380.44
200_N379_Y0.7380.44
54_R60_G0.7370.44
58_L316_W0.7340.44
190_G261_P0.7340.44
108_D446_I0.7340.44
315_H318_E0.7330.44
164_A303_R0.7320.44
89_Q92_E0.7320.44
105_W149_K0.7310.44
29_A32_G0.7310.44
25_Q272_N0.7310.44
182_D252_F0.7300.44
424_I445_L0.7290.43
188_F207_I0.7240.43
347_M367_T0.7230.43
49_R175_R0.7220.43
156_F184_A0.7200.43
283_F291_V0.7200.43
187_I199_I0.7190.43
94_L151_P0.7180.42
287_L312_A0.7180.42
94_L98_Y0.7170.42
203_W236_F0.7150.42
277_N404_Y0.7140.42
204_D336_F0.7140.42
409_D421_K0.7120.42
159_N353_L0.7120.42
166_I317_I0.7110.42
109_E112_F0.7110.42
193_L224_R0.7100.42
31_Q91_E0.7100.42
231_V342_K0.7090.42
226_T273_P0.7080.42
330_I340_A0.7070.42
27_T185_G0.7060.41
59_R305_C0.7040.41
342_K352_A0.7030.41
102_L151_P0.7020.41
47_Q176_S0.7010.41
52_V85_K0.7010.41
186_I229_L0.7000.41
197_P201_K0.6980.41
404_Y408_K0.6980.41
254_A338_D0.6970.41
76_K183_E0.6970.41
35_A378_W0.6960.41
419_I453_I0.6950.41
420_K435_R0.6920.40
75_R80_D0.6920.40
17_R358_S0.6920.40
364_I418_C0.6920.40
220_I281_P0.6920.40
47_Q230_M0.6900.40
257_L349_R0.6900.40
99_T102_L0.6890.40
32_G37_S0.6880.40
174_W177_V0.6880.40
104_A287_L0.6860.40
311_E372_A0.6840.40
95_F451_I0.6820.39
20_I311_E0.6820.39
117_K452_F0.6810.39
342_K383_Y0.6760.39
77_S316_W0.6760.39
185_G254_A0.6760.39
30_P33_L0.6750.39
186_I195_E0.6750.39
189_N403_L0.6740.39
43_S274_I0.6730.39
39_L375_I0.6720.39
227_L325_S0.6710.38
181_S185_G0.6700.38
250_I378_W0.6700.38
407_I410_Y0.6660.38
52_V367_T0.6660.38
184_A199_I0.6660.38
106_R109_E0.6650.38
314_R322_Q0.6630.38
51_D59_R0.6630.38
348_A352_A0.6620.38
71_E74_E0.6620.38
107_N400_A0.6620.38
316_W344_A0.6610.38
186_I201_K0.6610.38
174_W352_A0.6590.37
309_S369_V0.6580.37
180_M240_I0.6570.37
58_L342_K0.6570.37
165_A211_E0.6570.37
226_T429_P0.6550.37
181_S229_L0.6540.37
370_K409_D0.6520.37
14_K17_R0.6510.37
110_A208_F0.6490.37
51_D224_R0.6490.37
176_S229_L0.6490.37
232_Q364_I0.6480.37
82_L106_R0.6470.36
6_P188_F0.6470.36
347_M351_A0.6460.36
419_I451_I0.6460.36
14_K18_N0.6450.36
218_K311_E0.6450.36
16_I66_L0.6440.36
355_H363_D0.6430.36
324_E327_M0.6430.36
85_K309_S0.6420.36
229_L319_F0.6400.36
13_P16_I0.6390.36
437_K443_R0.6390.36
394_S441_L0.6380.36
57_N447_S0.6380.36
424_I432_F0.6350.36
334_Y423_I0.6330.35
70_A105_W0.6320.35
41_V66_L0.6310.35
74_E342_K0.6290.35
43_S103_T0.6260.35
187_I229_L0.6260.35
331_G340_A0.6260.35
84_M178_G0.6250.35
215_E382_E0.6240.35
254_A342_K0.6220.34
43_S62_V0.6210.34
53_C307_R0.6210.34
91_E219_L0.6190.34
168_A365_S0.6170.34
74_E266_G0.6160.34
83_L236_F0.6160.34
36_A375_I0.6160.34
312_A369_V0.6160.34
394_S404_Y0.6110.34
366_V455_S0.6080.33
22_E279_H0.6060.33
101_D113_N0.6060.33
318_E384_I0.6050.33
419_I424_I0.6040.33
114_I451_I0.6030.33
157_L278_E0.6030.33
274_I313_E0.6030.33
314_R457_G0.6020.33
312_A368_A0.6010.33
71_E238_G0.6000.33
161_A211_E0.6000.33
210_V220_I0.5990.33
226_T387_F0.5990.33
77_S232_Q0.5990.33
53_C305_C0.5980.33
197_P202_M0.5930.32
249_G335_D0.5900.32
53_C59_R0.5890.32
113_N315_H0.5880.32
305_C437_K0.5880.32
72_S200_N0.5870.32
230_M357_F0.5870.32
76_K232_Q0.5860.32
306_L406_W0.5850.32
406_W428_G0.5840.32
82_L426_Q0.5840.32
403_L429_P0.5830.31
36_A66_L0.5830.31
398_S401_D0.5820.31
147_N309_S0.5820.31
102_L150_A0.5810.31
6_P412_T0.5810.31
375_I399_E0.5810.31
118_A157_L0.5810.31
167_K208_F0.5810.31
54_R58_L0.5800.31
157_L394_S0.5800.31
33_L230_M0.5790.31
106_R443_R0.5790.31
20_I23_V0.5780.31
442_I446_I0.5770.31
87_L190_G0.5760.31
16_I77_S0.5760.31
452_F455_S0.5750.31
55_L313_E0.5740.31
442_I451_I0.5720.31
166_I225_I0.5710.31
45_A54_R0.5710.31
439_N443_R0.5710.31
321_N382_E0.5700.30
408_K419_I0.5700.30
181_S184_A0.5690.30
333_L338_D0.5680.30
275_F279_H0.5680.30
331_G338_D0.5680.30
79_V188_F0.5670.30
27_T432_F0.5660.30
36_A228_S0.5650.30
87_L308_F0.5640.30
79_V319_F0.5640.30
34_I308_F0.5630.30
197_P250_I0.5630.30
214_N220_I0.5630.30
339_Y382_E0.5620.30
403_L432_F0.5620.30
33_L229_L0.5610.30
65_F200_N0.5600.30
77_S245_D0.5600.30
226_T346_N0.5590.30
167_K187_I0.5580.30
198_F202_M0.5580.30
311_E314_R0.5580.30
29_A75_R0.5570.29
226_T353_L0.5570.29
238_G247_A0.5570.29
104_A309_S0.5560.29
109_E148_P0.5550.29
228_S257_L0.5550.29
84_M231_V0.5550.29
316_W320_Y0.5540.29
152_V172_G0.5540.29
344_A354_L0.5530.29
77_S205_G0.5530.29
195_E199_I0.5530.29
18_N450_K0.5520.29
270_I317_I0.5510.29
426_Q432_F0.5510.29
12_F194_N0.5500.29
66_L228_S0.5500.29
158_F447_S0.5490.29
240_I402_E0.5480.29
91_E156_F0.5470.29
182_D208_F0.5460.29
33_L47_Q0.5450.29
177_V325_S0.5450.29
429_P432_F0.5440.29
420_K439_N0.5420.28
253_F339_Y0.5420.28
75_R84_M0.5410.28
69_L424_I0.5410.28
68_T204_D0.5400.28
183_E255_R0.5380.28
66_L350_L0.5370.28
52_V348_A0.5370.28
231_V312_A0.5350.28
29_A197_P0.5350.28
236_F379_Y0.5350.28
203_W342_K0.5340.28
158_F161_A0.5300.28
20_I443_R0.5290.27
256_C340_A0.5280.27
78_T316_W0.5280.27
170_L225_I0.5280.27
184_A196_L0.5270.27
36_A259_C0.5270.27
252_F256_C0.5260.27
111_I353_L0.5260.27
55_L220_I0.5250.27
57_N168_A0.5250.27
160_D164_A0.5250.27
39_L106_R0.5240.27
195_E354_L0.5220.27
53_C56_N0.5220.27
61_P403_L0.5210.27
367_T371_A0.5200.27
262_A385_R0.5190.27
34_I77_S0.5180.27
163_P179_I0.5180.27
170_L227_L0.5160.27
173_H215_E0.5160.27
18_N374_E0.5160.27
59_R102_L0.5140.26
88_Y228_S0.5130.26
19_A280_L0.5120.26
63_S68_T0.5110.26
93_D96_E0.5100.26
428_G432_F0.5090.26
287_L291_V0.5090.26
406_W410_Y0.5090.26
55_L75_R0.5080.26
60_G200_N0.5070.26
43_S355_H0.5060.26
50_I350_L0.5050.26
75_R340_A0.5040.26
17_R214_N0.5040.26
109_E306_L0.5030.26
322_Q325_S0.5020.26
24_E38_A0.5020.26
68_T228_S0.5010.26
339_Y383_Y0.5000.25
292_N423_I0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4fdgB 1 0.6674 99.1 0.871 Contact Map
3ja84 1 0.6482 99.1 0.873 Contact Map
3ja87 1 0.6695 99 0.873 Contact Map
3ja85 1 0.6738 98.9 0.882 Contact Map
3ja86 1 0.6503 98.6 0.894 Contact Map
4r7yA 3 0.6525 98.2 0.905 Contact Map
3ja82 1 0.693 98.1 0.907 Contact Map
1w5sA 1 0.7719 97.4 0.92 Contact Map
2qbyA 1 0.7313 96.7 0.928 Contact Map
3pfiA 3 0.6183 96.7 0.928 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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