GREMLIN Database
YFHL - Uncharacterized ferredoxin-like protein YfhL
UniProt: P52102 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13215
Length: 86 (74)
Sequences: 677 (458)
Seq/√Len: 53.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_I34_N2.7501.00
44_H52_K2.7271.00
51_Q60_I2.3821.00
71_E75_D2.1251.00
46_E52_K2.0551.00
37_K41_C2.0051.00
20_P55_P1.8760.99
66_H70_E1.8260.99
40_E48_P1.7650.99
71_E74_W1.7290.99
25_S36_D1.7060.99
52_K60_I1.7000.99
21_N39_T1.5430.98
66_H73_L1.5230.97
37_K48_P1.5080.97
56_I76_K1.4250.96
68_E71_E1.3820.95
68_E72_Q1.3760.95
18_E22_E1.3750.95
13_D16_E1.3670.95
42_V46_E1.2880.93
10_I13_D1.2850.93
37_K40_E1.2500.92
43_G46_E1.2450.92
25_S77_F1.2160.91
26_M34_N1.1790.90
5_I8_K1.1680.89
27_G30_I1.1590.89
21_N37_K1.1170.87
44_H47_T1.1140.87
17_P53_V1.0990.86
26_M30_I1.0940.86
20_P37_K1.0700.85
11_N21_N1.0410.83
6_T24_I1.0370.83
15_C54_C1.0280.82
19_C50_C1.0280.82
15_C50_C1.0280.82
19_C54_C1.0280.82
15_C19_C1.0280.82
50_C54_C1.0280.82
6_T26_M1.0110.81
21_N40_E0.9880.80
66_H69_T0.9660.78
10_I59_T0.9470.77
4_L14_M0.9290.75
7_K29_H0.9070.74
23_A63_D0.9040.73
10_I55_P0.9020.73
61_V70_E0.8900.72
63_D76_K0.8860.72
37_K55_P0.8830.72
17_P48_P0.8620.70
72_Q77_F0.8560.69
13_D26_M0.8540.69
38_C50_C0.8340.67
15_C38_C0.8340.67
19_C38_C0.8340.67
38_C54_C0.8340.67
34_N52_K0.8240.66
35_S41_C0.8240.66
40_E62_K0.8200.66
44_H49_T0.8200.66
67_V71_E0.8180.66
21_N56_I0.7900.63
52_K68_E0.7770.62
9_C19_C0.7700.61
9_C54_C0.7700.61
9_C15_C0.7700.61
9_C50_C0.7700.61
74_W77_F0.7630.60
49_T55_P0.7620.60
41_C55_P0.7500.59
7_K43_G0.7410.58
62_K67_V0.7360.58
71_E76_K0.7300.57
37_K51_Q0.7180.56
30_I70_E0.7140.55
14_M35_S0.7080.55
36_D47_T0.7030.54
12_C19_C0.7020.54
12_C50_C0.7020.54
12_C15_C0.7020.54
12_C54_C0.7020.54
18_E71_E0.6920.53
47_T58_N0.6900.53
64_P72_Q0.6880.53
20_P49_T0.6860.52
58_N61_V0.6730.51
72_Q75_D0.6680.50
8_K21_N0.6590.49
27_G43_G0.6560.49
20_P40_E0.6530.49
66_H74_W0.6450.48
73_L77_F0.6240.46
25_S58_N0.6190.45
6_T34_N0.6080.44
36_D40_E0.6070.44
13_D22_E0.6000.43
11_N20_P0.5900.42
59_T69_T0.5800.41
9_C38_C0.5750.41
4_L43_G0.5750.41
16_E31_Y0.5670.40
8_K28_D0.5580.39
3_L69_T0.5550.39
14_M23_A0.5330.36
5_I43_G0.5090.34
11_N31_Y0.5060.34
52_K58_N0.5000.33
12_C38_C0.5000.33
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2zvsA 1 0.9419 99.6 0.34 Contact Map
2fgoA 1 0.9419 99.5 0.346 Contact Map
1rgvA 1 0.9302 99.5 0.359 Contact Map
3eunA 1 0.9419 99.5 0.36 Contact Map
1ti6B 2 0.9651 99.4 0.398 Contact Map
5c4iB 1 0.7326 99.4 0.4 Contact Map
4omfG 2 0.7442 99.3 0.416 Contact Map
2c42A 2 0.9186 99.3 0.416 Contact Map
1kqfB 3 0.9535 99.3 0.422 Contact Map
1h0hB 1 0.9535 99.3 0.425 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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