GREMLIN Database
DCLZ - Lysine decarboxylase, constitutive
UniProt: P52095 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13219
Length: 713 (670)
Sequences: 652 (284)
Seq/√Len: 11.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
633_E643_R6.2671.00
626_R631_E6.1821.00
451_F459_V5.8971.00
454_W459_V5.6111.00
456_P459_V5.4651.00
451_F454_W5.1871.00
559_S564_L5.1641.00
232_A257_V5.1561.00
468_A471_E4.9651.00
451_F456_P4.7891.00
149_T181_S4.6951.00
171_F178_A4.4211.00
563_N588_D4.2951.00
375_A408_S4.2710.99
80_Y120_Y4.1680.99
133_T410_E4.0650.99
205_A210_A3.7000.98
149_T183_S3.6960.98
348_G361_E3.6930.98
297_W300_H3.5810.98
446_S449_W3.5110.98
213_S379_H3.5100.98
517_F555_E3.3450.97
67_C79_L3.2580.96
220_T362_T3.2450.96
432_A537_F3.2020.96
565_R568_N3.1190.95
615_E664_M3.0690.95
563_N585_R3.0490.95
455_Q459_V3.0140.95
448_G451_F2.8820.93
448_G456_P2.7600.91
449_W456_P2.7590.91
449_W459_V2.7560.91
296_Q300_H2.6350.89
252_L327_I2.6310.89
585_R588_D2.6160.89
187_L389_F2.5880.88
451_F455_Q2.5810.88
448_G459_V2.5800.88
580_F592_G2.5590.88
226_I397_T2.5530.88
449_W454_W2.5310.87
491_V537_F2.5190.87
453_I459_V2.4920.86
627_Q656_V2.4760.86
636_A639_Q2.4610.86
296_Q299_V2.4440.85
227_V360_F2.4020.84
181_S527_K2.2770.81
446_S451_F2.2680.80
203_Y206_R2.2570.80
203_Y207_T2.2550.80
148_C395_M2.2540.80
53_C121_T2.2280.79
360_F389_F2.1590.77
454_W457_P2.1500.77
200_A215_I2.1460.76
149_T182_I2.1290.76
157_A416_L2.1270.76
214_Y386_E2.1220.76
509_I560_Y2.1110.75
67_C389_F2.0920.75
250_H396_H2.0740.74
453_I456_P2.0710.74
450_F459_V2.0680.74
451_F457_P2.0510.73
448_G454_W2.0510.73
466_P482_D2.0450.73
196_P232_A2.0290.72
234_S625_Q2.0070.71
167_F408_S2.0030.71
632_V646_A1.9960.71
197_H406_V1.9850.70
452_D459_V1.9780.70
204_I215_I1.9690.70
452_D456_P1.9380.69
153_M181_S1.9340.68
435_F537_F1.9290.68
226_I550_L1.9290.68
531_Y594_H1.9220.68
521_R555_E1.9200.68
217_T405_I1.8980.67
566_I580_F1.8920.67
215_I409_V1.8730.66
103_F117_M1.8730.66
192_D692_D1.8610.65
227_V257_V1.8370.64
117_M285_I1.7990.63
223_S656_V1.7250.59
178_A628_I1.7180.59
187_L197_H1.7150.59
376_S652_Y1.7110.58
225_K250_H1.6970.58
207_T417_R1.6910.58
175_T372_L1.6810.57
465_W475_G1.6700.57
450_F456_P1.6320.55
196_P509_I1.6250.54
165_C169_D1.6220.54
249_A660_M1.6110.54
349_M375_A1.6020.53
601_D604_G1.6010.53
133_T137_F1.5800.52
220_T225_K1.5750.52
371_A377_L1.5730.52
446_S456_P1.5590.51
175_T404_P1.5590.51
206_R417_R1.5580.51
398_T692_D1.5440.51
638_E677_L1.5430.50
139_Y149_T1.5380.50
149_T306_S1.5380.50
314_N482_D1.5370.50
412_A535_F1.5320.50
170_F178_A1.5310.50
283_D470_G1.5220.49
604_G608_R1.5140.49
187_L415_M1.5130.49
110_A114_A1.5120.49
454_W458_Q1.5080.49
183_S526_E1.5060.49
439_V553_L1.5060.49
574_Y578_P1.5040.49
499_D505_S1.5030.49
445_E561_D1.5020.48
203_Y417_R1.4970.48
567_K583_N1.4910.48
398_T526_E1.4820.48
238_L252_L1.4690.47
170_F174_N1.4690.47
173_G177_K1.4660.47
346_K462_A1.4640.47
469_P481_A1.4640.47
54_G80_Y1.4630.47
373_S401_P1.4630.47
130_P336_Y1.4620.47
267_N476_F1.4570.46
147_F274_G1.4560.46
148_C180_V1.4550.46
148_C181_S1.4510.46
287_E291_A1.4500.46
191_L218_N1.4500.46
446_S459_V1.4430.46
149_T153_M1.4400.46
218_N374_Q1.4300.45
247_S651_P1.4240.45
222_T360_F1.4010.44
198_L202_E1.4000.44
591_Q595_K1.3970.43
171_F388_A1.3960.43
275_I303_I1.3950.43
225_K396_H1.3920.43
115_I143_R1.3910.43
40_V48_H1.3820.43
223_S553_L1.3720.42
282_R286_E1.3690.42
517_F521_R1.3630.42
153_M183_S1.3500.41
204_I213_S1.3490.41
435_F491_V1.3370.41
447_D451_F1.3340.41
408_S674_D1.3210.40
143_R233_P1.3140.40
151_G376_S1.3110.39
393_F572_D1.3070.39
435_F540_G1.2990.39
376_S651_P1.2940.39
363_Q519_D1.2820.38
596_L600_H1.2820.38
274_G331_S1.2780.38
468_A481_A1.2750.38
157_A370_A1.2700.38
206_R521_R1.2620.37
449_W455_Q1.2610.37
149_T527_K1.2580.37
68_S98_M1.2520.37
148_C153_M1.2500.37
74_N157_A1.2440.36
331_S334_V1.2440.36
157_A491_V1.2430.36
212_Q386_E1.2400.36
410_E502_G1.2390.36
136_L407_A1.2370.36
674_D677_L1.2350.36
447_D454_W1.2330.36
218_N222_T1.2290.36
340_H425_I1.2230.36
241_D307_T1.2200.35
517_F559_S1.2110.35
233_P629_K1.2080.35
267_N497_G1.1980.34
306_S694_H1.1950.34
513_L590_A1.1930.34
53_C56_I1.1930.34
664_M668_E1.1920.34
305_N377_L1.1850.34
40_V43_L1.1840.34
577_D637_L1.1830.34
431_R546_A1.1830.34
171_F360_F1.1820.34
171_F206_R1.1820.34
305_N371_A1.1770.34
450_F454_W1.1740.33
641_V667_K1.1710.33
439_V501_Q1.1670.33
372_L402_S1.1650.33
240_I249_A1.1630.33
492_T532_N1.1600.33
323_D357_K1.1570.33
103_F127_N1.1550.33
316_D345_G1.1530.33
151_G652_Y1.1510.32
57_F81_A1.1510.32
225_K249_A1.1500.32
666_T674_D1.1500.32
373_S545_K1.1340.32
171_F363_Q1.1320.32
206_R617_I1.1270.31
447_D452_D1.1260.31
448_G453_I1.1260.31
180_V379_H1.1250.31
191_L399_T1.1240.31
184_V527_K1.1190.31
317_W320_Q1.1140.31
618_M626_R1.1140.31
189_S305_N1.0960.30
187_L384_Y1.0950.30
181_S185_T1.0930.30
161_S391_E1.0910.30
79_L223_S1.0900.30
368_M489_V1.0890.30
326_S358_V1.0890.30
163_V210_A1.0830.30
315_T327_I1.0830.30
448_G452_D1.0760.29
204_I256_D1.0750.29
451_F458_Q1.0750.29
156_T389_F1.0750.29
456_P460_D1.0750.29
617_I664_M1.0710.29
377_L409_V1.0660.29
81_A294_Q1.0650.29
55_V642_G1.0610.29
226_I238_L1.0580.29
157_A432_A1.0580.29
160_K560_Y1.0560.29
316_D320_Q1.0500.28
500_E505_S1.0490.28
220_T253_M1.0440.28
281_T321_T1.0420.28
181_S534_L1.0410.28
201_E231_A1.0410.28
250_H395_M1.0410.28
149_T184_V1.0380.28
226_I378_I1.0370.28
240_I292_T1.0370.28
411_T594_H1.0360.28
544_T553_L1.0360.28
234_S621_H1.0330.28
506_E586_I1.0320.28
599_K685_H1.0300.28
149_T311_L1.0280.27
444_E561_D1.0270.27
285_I289_V1.0260.27
115_I148_C1.0240.27
148_C312_L1.0220.27
139_Y220_T1.0200.27
667_K674_D1.0160.27
299_V538_S1.0150.27
279_E288_K1.0140.27
429_V489_V1.0130.27
216_V397_T1.0120.27
371_A412_A1.0100.27
341_P531_Y1.0070.27
71_N98_M1.0070.27
427_R430_E1.0070.27
378_I589_L1.0050.27
80_Y646_A1.0050.27
69_D77_L1.0000.26
137_F517_F0.9990.26
392_A651_P0.9990.26
181_S184_V0.9950.26
149_T189_S0.9940.26
141_K468_A0.9940.26
132_F303_I0.9890.26
331_S346_K0.9890.26
192_D304_T0.9880.26
221_S396_H0.9870.26
471_E506_E0.9860.26
666_T672_V0.9790.26
139_Y393_F0.9790.26
64_L83_I0.9770.26
205_A689_F0.9770.26
139_Y191_L0.9770.26
252_L606_M0.9760.26
269_L544_T0.9760.26
384_Y559_S0.9750.25
401_P421_G0.9750.25
221_S250_H0.9740.25
221_S401_P0.9730.25
247_S652_Y0.9650.25
290_A562_L0.9620.25
209_G331_S0.9610.25
175_T509_I0.9610.25
175_T359_I0.9600.25
57_F66_L0.9600.25
276_P660_M0.9590.25
624_W628_I0.9580.25
176_L427_R0.9570.25
551_R554_T0.9570.25
409_V529_G0.9570.25
180_V483_H0.9520.25
191_L216_V0.9490.25
38_N363_Q0.9480.25
261_W394_M0.9480.25
231_A360_F0.9470.24
207_T223_S0.9440.24
170_F384_Y0.9440.24
545_K614_P0.9440.24
252_L315_T0.9430.24
250_H275_I0.9420.24
84_N95_D0.9410.24
139_Y280_F0.9390.24
254_M285_I0.9370.24
288_K291_A0.9370.24
331_S337_T0.9350.24
528_T660_M0.9350.24
476_F497_G0.9320.24
240_I492_T0.9310.24
449_W457_P0.9290.24
227_V238_L0.9280.24
277_R354_V0.9260.24
426_N644_V0.9250.24
262_L280_F0.9250.24
40_V461_E0.9230.24
499_D586_I0.9220.24
64_L98_M0.9170.23
224_N652_Y0.9160.23
182_I262_L0.9150.23
575_A701_D0.9120.23
175_T402_S0.9120.23
60_D360_F0.9120.23
473_W476_F0.9110.23
449_W453_I0.9100.23
590_A594_H0.9100.23
190_L688_G0.9070.23
109_Q548_G0.9060.23
534_L661_P0.9060.23
506_E575_A0.9030.23
461_E472_Q0.9030.23
148_C183_S0.9020.23
523_I644_V0.9020.23
285_I318_I0.9010.23
150_P490_K0.9010.23
71_N94_Q0.9000.23
301_A610_F0.8990.23
46_I97_R0.8990.23
65_D644_V0.8990.23
543_K547_M0.8980.23
689_F692_D0.8980.23
278_R320_Q0.8980.23
497_G581_Y0.8970.23
327_I525_V0.8970.23
133_T682_V0.8950.23
331_S485_F0.8940.23
243_N371_A0.8930.23
536_L545_K0.8930.23
200_A409_V0.8920.23
528_T560_Y0.8920.23
272_L376_S0.8910.23
341_P487_D0.8900.23
447_D456_P0.8900.23
132_F200_A0.8890.22
250_H657_P0.8880.22
260_V659_L0.8880.22
170_F651_P0.8880.22
276_P486_L0.8870.22
584_M592_G0.8870.22
183_S483_H0.8860.22
101_W128_I0.8860.22
224_N651_P0.8850.22
167_F171_F0.8840.22
122_D701_D0.8830.22
181_S377_L0.8810.22
149_T694_H0.8770.22
392_A628_I0.8770.22
492_T594_H0.8720.22
151_G272_L0.8700.22
189_S371_A0.8700.22
237_T289_V0.8660.22
132_F220_T0.8660.22
499_D640_L0.8600.22
588_D674_D0.8590.21
52_I644_V0.8570.21
394_M573_L0.8540.21
506_E598_R0.8530.21
213_S405_I0.8520.21
92_S95_D0.8520.21
202_E260_V0.8490.21
183_S527_K0.8480.21
363_Q379_H0.8480.21
470_G477_N0.8460.21
101_W215_I0.8440.21
84_N174_N0.8440.21
196_P693_I0.8420.21
532_N678_M0.8410.21
298_P673_L0.8410.21
34_I320_Q0.8400.21
83_I701_D0.8400.21
206_R420_P0.8390.21
171_F673_L0.8390.21
285_I293_T0.8380.21
336_Y455_Q0.8370.21
221_S395_M0.8350.21
49_N482_D0.8340.21
253_M393_F0.8330.21
223_S413_A0.8330.21
268_A659_L0.8320.21
247_S392_A0.8320.21
372_L379_H0.8320.21
540_G560_Y0.8320.21
288_K389_F0.8310.21
446_S454_W0.8310.21
186_E285_I0.8300.21
409_V691_T0.8300.21
213_S645_S0.8290.21
394_M403_Y0.8260.20
218_N391_E0.8240.20
455_Q509_I0.8230.20
181_S305_N0.8220.20
421_G487_D0.8220.20
278_R284_S0.8210.20
379_H394_M0.8200.20
45_F67_C0.8200.20
447_D459_V0.8190.20
151_G623_A0.8180.20
190_L511_A0.8180.20
237_T276_P0.8160.20
311_L603_P0.8150.20
240_I244_C0.8150.20
335_P377_L0.8130.20
551_R558_R0.8130.20
574_Y577_D0.8120.20
223_S471_E0.8110.20
285_I660_M0.8090.20
264_P369_L0.8090.20
482_D506_E0.8080.20
208_F604_G0.8070.20
57_F405_I0.8070.20
225_K657_P0.8020.20
200_A223_S0.8020.20
294_Q622_Q0.8020.20
216_V329_F0.8020.20
517_F672_V0.8020.20
365_T377_L0.8010.20
514_V533_L0.8010.20
302_V559_S0.7960.20
221_S373_S0.7950.19
393_F433_L0.7950.19
258_V656_V0.7940.19
244_C304_T0.7920.19
180_V228_G0.7920.19
435_F486_L0.7900.19
55_V77_L0.7890.19
257_V678_M0.7880.19
512_A673_L0.7860.19
114_A438_E0.7860.19
327_I359_I0.7840.19
176_L525_V0.7840.19
452_D457_P0.7840.19
140_V394_M0.7830.19
115_I180_V0.7830.19
354_V380_I0.7830.19
700_E703_V0.7830.19
182_I660_M0.7800.19
617_I644_V0.7800.19
52_I481_A0.7800.19
161_S218_N0.7790.19
271_I552_G0.7780.19
489_V657_P0.7760.19
372_L519_D0.7750.19
89_M103_F0.7750.19
522_G559_S0.7750.19
659_L676_L0.7750.19
523_I674_D0.7740.19
217_T491_V0.7740.19
571_P581_Y0.7730.19
432_A543_K0.7720.19
531_Y535_F0.7710.19
225_K398_T0.7710.19
109_Q112_D0.7690.19
176_L526_E0.7690.19
304_T657_P0.7680.19
135_A369_L0.7680.19
267_N473_W0.7680.19
209_G511_A0.7670.19
306_S391_E0.7660.19
555_E558_R0.7630.19
94_Q126_D0.7600.18
52_I66_L0.7600.18
401_P410_E0.7600.18
322_L486_L0.7590.18
398_T527_K0.7590.18
505_S622_Q0.7580.18
198_L482_D0.7570.18
122_D503_N0.7570.18
202_E565_R0.7570.18
439_V554_T0.7570.18
203_Y410_E0.7560.18
218_N329_F0.7540.18
516_K529_G0.7540.18
340_H648_M0.7540.18
33_I65_D0.7520.18
207_T413_A0.7520.18
224_N376_S0.7520.18
699_D703_V0.7510.18
213_S335_P0.7510.18
33_I493_I0.7510.18
65_D439_V0.7490.18
32_Q36_P0.7460.18
131_P421_G0.7460.18
267_N370_A0.7450.18
79_L627_Q0.7450.18
72_Q562_L0.7450.18
146_T646_A0.7430.18
82_F562_L0.7430.18
248_L302_V0.7430.18
262_L570_L0.7420.18
287_E290_A0.7410.18
340_H361_E0.7410.18
84_N562_L0.7390.18
496_P508_G0.7380.18
200_A527_K0.7380.18
615_E674_D0.7360.18
262_L275_I0.7360.18
133_T215_I0.7350.18
40_V288_K0.7350.18
117_M637_L0.7340.18
446_S450_F0.7340.18
209_G338_H0.7330.18
134_K638_E0.7320.18
176_L340_H0.7320.18
222_T398_T0.7320.18
42_L45_F0.7320.18
112_D154_G0.7320.18
208_F369_L0.7320.18
304_T337_T0.7320.18
389_F640_L0.7300.18
225_K238_L0.7300.18
356_G361_E0.7300.18
429_V485_F0.7270.18
126_D639_Q0.7270.18
190_L526_E0.7260.17
311_L532_N0.7250.17
271_I486_L0.7250.17
55_V674_D0.7240.17
408_S452_D0.7240.17
192_D398_T0.7240.17
427_R506_E0.7230.17
135_A375_A0.7210.17
148_C525_V0.7180.17
604_G622_Q0.7170.17
279_E343_Y0.7170.17
83_I91_V0.7160.17
564_L576_E0.7150.17
63_S565_R0.7140.17
346_K484_M0.7120.17
115_I198_L0.7120.17
58_D61_E0.7110.17
314_N392_A0.7110.17
580_F668_E0.7100.17
52_I444_E0.7100.17
482_D701_D0.7090.17
218_N398_T0.7080.17
269_L321_T0.7080.17
231_A610_F0.7080.17
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119_Q554_T0.7070.17
81_A95_D0.7060.17
494_L500_E0.7060.17
222_T627_Q0.7060.17
77_L181_S0.7060.17
194_T398_T0.7050.17
558_R601_D0.7050.17
379_H573_L0.7050.17
80_Y303_I0.7040.17
59_W63_S0.7030.17
36_P211_E0.7030.17
277_R482_D0.7030.17
190_L410_E0.7030.17
431_R537_F0.7020.17
232_A678_M0.7010.17
167_F311_L0.7010.17
82_F114_A0.7000.17
224_N247_S0.7000.17
213_S410_E0.7000.17
34_I286_E0.6990.17
139_Y153_M0.6990.17
147_F331_S0.6990.17
187_L344_Q0.6980.17
182_I305_N0.6970.17
311_L484_M0.6970.17
31_F118_R0.6950.17
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455_Q458_Q0.6920.17
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465_W474_H0.6920.17
262_L399_T0.6920.17
221_S424_L0.6910.17
56_I103_F0.6910.17
143_R383_E0.6910.17
435_F546_A0.6900.17
198_L553_L0.6900.17
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289_V622_Q0.6880.16
144_K372_L0.6880.16
163_V411_T0.6880.16
392_A679_L0.6870.16
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398_T495_T0.6860.16
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447_D450_F0.6750.16
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395_M624_W0.6730.16
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421_G424_L0.6410.15
292_T616_M0.6410.15
391_E398_T0.6410.15
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358_V425_I0.6400.15
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465_W476_F0.6380.15
121_T211_E0.6370.15
135_A613_L0.6370.15
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302_V692_D0.6350.15
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430_E434_H0.6300.15
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190_L374_Q0.6290.15
396_H659_L0.6290.15
148_C192_D0.6280.15
82_F411_T0.6270.15
196_P290_A0.6270.15
630_G643_R0.6260.15
70_I385_D0.6260.15
428_S692_D0.6250.15
631_E644_V0.6240.15
372_L437_K0.6230.15
302_V336_Y0.6230.15
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274_G484_M0.6210.15
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331_S361_E0.6200.15
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371_A538_S0.6110.15
387_E697_K0.6110.15
45_F48_H0.6110.15
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104_E125_L0.6100.14
524_V649_I0.6100.14
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51_R118_R0.5910.14
612_T615_E0.5910.14
418_G422_K0.5910.14
78_P581_Y0.5900.14
255_N621_H0.5900.14
499_D503_N0.5900.14
154_G415_M0.5900.14
342_I485_F0.5890.14
305_N336_Y0.5890.14
48_H322_L0.5890.14
283_D287_E0.5880.14
65_D664_M0.5870.14
392_A681_S0.5860.14
209_G343_Y0.5850.14
291_A641_V0.5850.14
196_P255_N0.5850.14
534_L688_G0.5840.14
298_P521_R0.5840.14
214_Y461_E0.5820.14
371_A425_I0.5820.14
187_L196_P0.5820.14
150_P473_W0.5810.14
363_Q403_Y0.5800.14
491_V546_A0.5790.14
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254_M389_F0.5780.14
377_L434_H0.5780.14
506_E637_L0.5770.14
374_Q527_K0.5770.14
657_P678_M0.5770.14
191_L329_F0.5770.14
114_A285_I0.5770.14
306_S331_S0.5770.14
335_P521_R0.5760.14
111_E433_L0.5760.14
200_A526_E0.5750.14
132_F215_I0.5750.14
218_N225_K0.5740.14
95_D393_F0.5740.14
365_T416_L0.5730.14
99_A223_S0.5730.14
56_I85_T0.5730.14
461_E532_N0.5730.14
92_S636_A0.5730.14
275_I313_Y0.5730.14
148_C694_H0.5720.14
223_S462_A0.5710.14
199_E417_R0.5710.14
498_M593_I0.5710.14
306_S334_V0.5700.14
167_F517_F0.5700.14
249_A657_P0.5690.14
289_V517_F0.5690.14
92_S101_W0.5680.14
508_G581_Y0.5650.13
67_C95_D0.5650.13
482_D601_D0.5620.13
101_W527_K0.5620.13
288_K572_D0.5620.13
103_F125_L0.5600.13
306_S395_M0.5600.13
595_K598_R0.5590.13
165_C596_L0.5590.13
223_S586_I0.5590.13
70_I438_E0.5580.13
334_V337_T0.5580.13
311_L486_L0.5580.13
89_M470_G0.5580.13
450_F455_Q0.5580.13
304_T412_A0.5570.13
190_L313_Y0.5570.13
425_I648_M0.5570.13
186_E499_D0.5560.13
520_E701_D0.5560.13
198_L644_V0.5560.13
154_G373_S0.5540.13
90_D98_M0.5540.13
381_K629_K0.5540.13
497_G508_G0.5540.13
146_T208_F0.5540.13
142_E160_K0.5530.13
305_N334_V0.5520.13
338_H381_K0.5520.13
566_I574_Y0.5520.13
377_L455_Q0.5520.13
375_A392_A0.5520.13
253_M600_H0.5520.13
427_R438_E0.5520.13
371_A530_P0.5520.13
148_C406_V0.5510.13
229_M254_M0.5510.13
90_D95_D0.5490.13
378_I389_F0.5490.13
240_I594_H0.5480.13
133_T213_S0.5480.13
223_S382_G0.5480.13
162_P496_P0.5470.13
296_Q700_E0.5470.13
584_M590_A0.5470.13
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171_F498_M0.5460.13
450_F561_D0.5460.13
225_K280_F0.5460.13
595_K604_G0.5450.13
69_D97_R0.5450.13
101_W548_G0.5450.13
297_W325_P0.5450.13
67_C360_F0.5440.13
312_L417_R0.5440.13
152_H623_A0.5430.13
125_L280_F0.5420.13
389_F493_I0.5420.13
275_I399_T0.5420.13
598_R674_D0.5410.13
252_L689_F0.5410.13
506_E685_H0.5400.13
97_R141_K0.5400.13
314_N462_A0.5400.13
220_T326_S0.5400.13
74_N509_I0.5390.13
656_V659_L0.5380.13
244_C425_I0.5380.13
91_V137_F0.5370.13
379_H382_G0.5360.13
482_D512_A0.5360.13
181_S189_S0.5340.13
274_G479_A0.5340.13
331_S410_E0.5330.13
235_G258_V0.5330.13
201_E249_A0.5330.13
311_L372_L0.5320.13
187_L680_C0.5310.13
597_I600_H0.5310.13
43_L199_E0.5300.13
318_I532_N0.5300.13
452_D455_Q0.5300.13
368_M425_I0.5300.13
176_L274_G0.5300.13
97_R354_V0.5280.13
69_D72_Q0.5270.13
146_T596_L0.5270.13
285_I531_Y0.5270.13
225_K397_T0.5270.13
553_L659_L0.5270.13
309_D333_W0.5260.13
141_K637_L0.5250.13
401_P614_P0.5250.13
401_P545_K0.5250.13
181_S526_E0.5250.13
306_S527_K0.5250.13
235_G602_L0.5240.13
410_E421_G0.5240.13
431_R491_V0.5240.13
107_L389_F0.5230.13
191_L225_K0.5230.13
300_H527_K0.5230.13
57_F680_C0.5220.13
565_R595_K0.5220.13
44_K67_C0.5220.13
440_Q541_I0.5220.13
527_K532_N0.5210.13
178_A247_S0.5210.13
113_I555_E0.5200.12
38_N408_S0.5200.12
117_M693_I0.5200.12
184_V526_E0.5200.12
322_L464_C0.5200.12
38_N558_R0.5190.12
537_F541_I0.5180.12
42_L644_V0.5180.12
94_Q97_R0.5160.12
198_L201_E0.5160.12
216_V421_G0.5150.12
656_V680_C0.5150.12
154_G312_L0.5150.12
32_Q37_Q0.5140.12
177_K541_I0.5130.12
369_L540_G0.5130.12
181_S660_M0.5130.12
97_R601_D0.5120.12
160_K624_W0.5120.12
365_T396_H0.5120.12
82_F700_E0.5110.12
468_A472_Q0.5110.12
180_V183_S0.5100.12
377_L682_V0.5100.12
199_E248_L0.5090.12
464_C494_L0.5090.12
94_Q119_Q0.5090.12
390_N675_F0.5080.12
303_I515_A0.5080.12
209_G656_V0.5070.12
117_M453_I0.5070.12
152_H536_L0.5070.12
315_T356_G0.5070.12
191_L220_T0.5070.12
216_V386_E0.5070.12
223_S234_S0.5060.12
413_A610_F0.5060.12
154_G395_M0.5050.12
409_V594_H0.5050.12
131_P275_I0.5040.12
227_V363_Q0.5040.12
42_L140_V0.5030.12
365_T561_D0.5030.12
189_S377_L0.5020.12
384_Y505_S0.5010.12
134_K180_V0.5000.12
589_L689_F0.5000.12
84_N111_E0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2vycA 5 0.9958 100 0.511 Contact Map
3n75A 4 0.9972 100 0.531 Contact Map
1c4kA 2 0.9607 100 0.547 Contact Map
2x3lA 2 0.5849 100 0.738 Contact Map
4q6rA 2 0.5638 100 0.883 Contact Map
3mc6A 2 0.5414 100 0.894 Contact Map
4w8iA 2 0.4853 99.9 0.92 Contact Map
3bc8A 3 0.575 99.8 0.933 Contact Map
3hl2A 3 0.5708 99.8 0.936 Contact Map
1js3A 2 0.5624 99.7 0.937 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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