YGGP - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YGGP - Uncharacterized protein YggP

UniProt:	P52048	Sequences: MKTKVAAIYGKRDVRLRVFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYHTTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVELAASKGIELVYVNTKGMSDPVQMLRALTGDAGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQLQPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEETHGIWNEQAEKYLLAQFGVDIGEAAQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12976
Length:	425 (324)
Sequences:	17740 (11268)
Seq/√Len:	626.0

ECOLI - YGGP YBDR FRMA YDJL GATD YDJJ RSPB YAHK YJJN YPHC TDH ADHP AHR QOR1 YCJQ IDND ACUI CURA
BACSU - YYCR ADHB YJMD TDH DHSO YOGA BDHA ADHA YHFP YFMJ
HALSA - Q9HP38 Q9HMB6 Q9HQS8 GLCDH Q9HR85
SULSO - ADH Q7LXK1 Q97VV5 Q97XR4 Q97YT7 Q97ZV3 Q97YM2 GLCD1 GLCD2 Q97VW0 Q97TZ4 Q97V32 Q97WA1 GLCD3 Q97W06 Q97VB8 Q97UW5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
348_A	351_E	3.224	1.00
9_Y	17_R	3.021	1.00
34_I	73_V	2.907	1.00
32_S	75_V	2.774	1.00
248_M	251_A	2.672	1.00
9_Y	15_R	2.588	1.00
89_Q	133_P	2.559	1.00
34_I	139_F	2.467	1.00
29_L	131_V	2.463	1.00
26_D	79_K	2.419	1.00
27_N	80_N	2.349	1.00
70_C	114_G	2.332	1.00
354_L	358_D	2.328	1.00
212_D	216_A	2.323	1.00
177_N	204_R	2.318	1.00
345_G	348_A	2.288	1.00
47_L	357_P	2.264	1.00
327_A	331_T	2.208	1.00
30_L	75_V	2.205	1.00
140_A	343_I	2.198	1.00
23_E	76_E	2.196	1.00
184_A	207_V	2.177	1.00
26_D	80_N	2.152	1.00
204_R	235_V	2.145	1.00
344_G	355_N	2.140	1.00
179_A	258_F	2.131	1.00
196_I	224_V	2.129	1.00
278_L	284_L	2.094	1.00
220_K	338_F	2.040	1.00
343_I	367_Y	2.036	1.00
216_A	220_K	2.016	1.00
32_S	73_V	2.007	1.00
216_A	219_Q	1.957	1.00
134_Y	142_A	1.953	1.00
99_L	102_G	1.950	1.00
102_G	105_A	1.914	1.00
7_A	17_R	1.913	1.00
212_D	238_N	1.885	1.00
283_C	310_H	1.883	1.00
83_G	123_E	1.879	1.00
137_S	330_A	1.871	1.00
342_H	355_N	1.847	1.00
179_A	208_V	1.843	1.00
344_G	352_T	1.843	1.00
30_L	120_I	1.801	1.00
217_Q	220_K	1.798	1.00
335_Q	338_F	1.795	1.00
6_A	349_V	1.792	1.00
32_S	118_Y	1.786	1.00
173_K	176_G	1.786	1.00
178_I	195_A	1.783	1.00
4_K	347_D	1.776	1.00
25_T	28_E	1.771	1.00
86_K	89_Q	1.767	1.00
4_K	18_V	1.748	1.00
77_V	87_K	1.734	1.00
259_D	279_A	1.721	1.00
192_I	223_P	1.716	1.00
215_L	219_Q	1.699	1.00
327_A	330_A	1.677	1.00
90_R	139_F	1.665	1.00
351_E	354_L	1.659	1.00
141_A	337_S	1.645	1.00
74_I	85_Y	1.644	1.00
156_H	324_E	1.639	1.00
76_E	87_K	1.634	1.00
224_V	235_V	1.623	1.00
244_D	247_Q	1.621	1.00
235_V	252_L	1.616	1.00
24_I	30_L	1.614	1.00
350_P	354_L	1.613	1.00
351_E	355_N	1.612	1.00
278_L	309_T	1.610	1.00
261_I	278_L	1.609	1.00
283_C	312_V	1.580	1.00
210_I	239_T	1.577	1.00
192_I	207_V	1.559	1.00
21_L	118_Y	1.553	1.00
78_G	81_L	1.540	1.00
156_H	198_G	1.533	1.00
206_V	258_F	1.521	1.00
215_L	236_Y	1.520	1.00
4_K	117_T	1.514	1.00
29_L	85_Y	1.513	1.00
243_S	248_M	1.506	1.00
85_Y	133_P	1.498	1.00
24_I	120_I	1.494	1.00
261_I	274_A	1.481	1.00
90_R	136_G	1.480	1.00
75_V	118_Y	1.479	1.00
73_V	139_F	1.476	1.00
70_C	93_L	1.459	1.00
247_Q	251_A	1.443	1.00
355_N	360_P	1.440	1.00
265_A	270_V	1.438	1.00
276_E	303_N	1.433	1.00
85_Y	131_V	1.431	1.00
28_E	120_I	1.430	1.00
10_G	13_D	1.424	1.00
33_V	70_C	1.413	1.00
21_L	30_L	1.411	1.00
99_L	105_A	1.388	1.00
219_Q	236_Y	1.387	1.00
248_M	252_L	1.380	1.00
209_D	215_L	1.377	1.00
28_E	122_P	1.359	1.00
9_Y	13_D	1.357	1.00
35_S	367_Y	1.355	1.00
5_V	19_F	1.353	1.00
204_R	224_V	1.350	1.00
191_A	262_F	1.323	1.00
71_A	139_F	1.315	1.00
278_L	282_G	1.310	1.00
176_G	283_C	1.310	1.00
90_R	134_Y	1.302	1.00
272_E	276_E	1.287	1.00
73_V	90_R	1.279	1.00
27_N	123_E	1.269	1.00
36_D	114_G	1.262	1.00
184_A	209_D	1.256	1.00
176_G	260_D	1.235	1.00
24_I	28_E	1.228	1.00
169_R	310_H	1.217	1.00
215_L	238_N	1.217	1.00
242_M	248_M	1.216	1.00
35_S	140_A	1.211	1.00
30_L	76_E	1.205	1.00
170_M	285_N	1.197	1.00
179_A	277_L	1.183	1.00
30_L	118_Y	1.178	1.00
85_Y	89_Q	1.173	1.00
274_A	284_L	1.170	1.00
210_I	240_K	1.158	1.00
38_V	352_T	1.157	1.00
212_D	242_M	1.150	1.00
345_G	367_Y	1.150	1.00
6_A	16_L	1.149	1.00
346_L	368_N	1.139	1.00
140_A	367_Y	1.124	1.00
19_F	65_I	1.118	1.00
135_H	330_A	1.114	1.00
33_V	119_M	1.114	1.00
246_V	250_R	1.111	1.00
177_N	206_V	1.097	1.00
181_L	270_V	1.093	1.00
31_V	72_G	1.092	1.00
249_L	258_F	1.089	1.00
148_M	190_G	1.086	1.00
19_F	112_F	1.082	1.00
246_V	276_E	1.079	1.00
268_P	272_E	1.078	1.00
199_G	202_P	1.076	1.00
207_V	218_V	1.065	1.00
145_A	329_S	1.057	1.00
213_K	216_A	1.055	1.00
31_V	91_F	1.049	1.00
210_I	215_L	1.048	1.00
183_C	207_V	1.048	1.00
208_V	239_T	1.039	1.00
181_L	208_V	1.036	1.00
154_A	287_F	1.032	1.00
170_M	260_D	1.026	1.00
192_I	205_V	1.018	1.00
27_N	122_P	1.017	1.00
75_V	87_K	1.017	1.00
32_S	117_T	1.016	1.00
156_H	321_D	1.009	1.00
207_V	223_P	1.003	1.00
193_D	335_Q	0.993	1.00
267_V	270_V	0.992	1.00
304_V	311_V	0.990	1.00
151_I	194_Y	0.990	1.00
103_Y	256_A	0.985	1.00
172_V	176_G	0.980	1.00
181_L	274_A	0.980	1.00
238_N	242_M	0.979	1.00
7_A	19_F	0.977	1.00
34_I	71_A	0.971	1.00
272_E	296_K	0.970	1.00
21_L	76_E	0.969	1.00
151_I	191_A	0.969	1.00
197_N	333_Q	0.969	1.00
206_V	252_L	0.967	1.00
35_S	365_L	0.962	1.00
349_V	366_I	0.950	1.00
7_A	65_I	0.949	1.00
152_I	325_A	0.944	1.00
344_G	366_I	0.944	1.00
175_G	203_S	0.943	1.00
176_G	259_D	0.942	1.00
77_V	86_K	0.941	1.00
258_F	261_I	0.939	1.00
33_V	368_N	0.937	1.00
103_Y	279_A	0.937	1.00
324_E	327_A	0.937	1.00
354_L	357_P	0.937	1.00
197_N	328_L	0.932	1.00
5_V	65_I	0.929	1.00
153_G	308_S	0.925	1.00
246_V	277_L	0.923	1.00
196_I	205_V	0.923	1.00
153_G	321_D	0.919	1.00
344_G	348_A	0.916	1.00
177_N	259_D	0.916	1.00
261_I	284_L	0.905	1.00
3_T	21_L	0.905	1.00
103_Y	259_D	0.902	1.00
180_L	195_A	0.902	1.00
6_A	346_L	0.901	1.00
115_N	366_I	0.901	1.00
39_C	69_E	0.901	1.00
141_A	335_Q	0.899	1.00
35_S	139_F	0.898	1.00
134_Y	139_F	0.896	1.00
304_V	313_G	0.894	1.00
328_L	333_Q	0.889	1.00
244_D	248_M	0.885	1.00
115_N	353_V	0.880	1.00
27_N	79_K	0.876	1.00
3_T	117_T	0.874	1.00
39_C	68_H	0.869	1.00
303_N	307_N	0.864	1.00
253_T	257_G	0.862	1.00
36_D	115_N	0.858	1.00
172_V	202_P	0.854	1.00
70_C	119_M	0.852	1.00
181_L	261_I	0.850	1.00
151_I	190_G	0.848	1.00
249_L	277_L	0.843	1.00
212_D	215_L	0.842	1.00
246_V	273_M	0.835	1.00
34_I	90_R	0.834	1.00
64_V	112_F	0.832	1.00
115_N	349_V	0.828	1.00
323_K	327_A	0.828	1.00
180_L	207_V	0.825	1.00
3_T	116_A	0.823	1.00
16_L	347_D	0.823	1.00
6_A	14_V	0.822	1.00
341_T	362_G	0.817	1.00
6_A	350_P	0.816	1.00
138_Y	141_A	0.813	1.00
329_S	336_P	0.808	1.00
177_N	203_S	0.806	1.00
184_A	192_I	0.803	1.00
82_T	123_E	0.801	1.00
361_G	364_K	0.801	1.00
342_H	361_G	0.798	1.00
94_Q	132_L	0.794	1.00
35_S	368_N	0.792	1.00
77_V	81_L	0.792	1.00
244_D	273_M	0.790	1.00
86_K	133_P	0.787	1.00
25_T	120_I	0.786	1.00
340_V	343_I	0.786	1.00
206_V	237_V	0.778	1.00
206_V	249_L	0.776	1.00
93_L	121_I	0.771	1.00
145_A	326_I	0.770	1.00
261_I	277_L	0.768	1.00
22_P	30_L	0.768	1.00
171_G	312_V	0.768	1.00
124_I	130_C	0.765	1.00
27_N	78_G	0.762	1.00
21_L	75_V	0.761	1.00
268_P	298_P	0.760	1.00
344_G	364_K	0.760	1.00
202_P	205_V	0.758	1.00
272_E	298_P	0.754	1.00
151_I	155_Y	0.753	1.00
91_F	131_V	0.750	1.00
38_V	115_N	0.748	1.00
121_I	131_V	0.746	1.00
83_G	86_K	0.745	1.00
237_V	245_P	0.742	1.00
152_I	156_H	0.741	1.00
186_P	363_K	0.741	1.00
219_Q	235_V	0.740	1.00
211_D	214_R	0.738	1.00
71_A	143_S	0.738	1.00
191_A	264_Y	0.736	1.00
155_Y	194_Y	0.733	1.00
190_G	339_M	0.732	1.00
46_A	357_P	0.730	1.00
138_Y	142_A	0.729	1.00
209_D	239_T	0.728	1.00
281_D	308_S	0.726	1.00
179_A	249_L	0.725	1.00
189_I	218_V	0.724	1.00
24_I	76_E	0.720	1.00
178_I	202_P	0.720	1.00
263_V	266_A	0.718	1.00
193_D	338_F	0.717	1.00
193_D	221_L	0.715	1.00
304_V	309_T	0.715	1.00
177_N	258_F	0.710	1.00
269_A	272_E	0.709	1.00
135_H	138_Y	0.707	1.00
24_I	78_G	0.705	1.00
169_R	312_V	0.702	1.00
215_L	239_T	0.702	1.00
155_Y	195_A	0.700	1.00
90_R	137_S	0.698	1.00
280_E	307_N	0.690	1.00
194_Y	325_A	0.689	1.00
237_V	248_M	0.689	1.00
247_Q	250_R	0.687	1.00
286_F	311_V	0.687	1.00
191_A	287_F	0.686	1.00
171_G	283_C	0.686	1.00
212_D	219_Q	0.684	1.00
108_S	112_F	0.683	1.00
260_D	283_C	0.678	1.00
294_N	300_N	0.676	1.00
235_V	248_M	0.674	1.00
151_I	187_M	0.669	1.00
23_E	30_L	0.669	1.00
189_I	362_G	0.664	1.00
271_V	286_F	0.664	1.00
285_N	312_V	0.658	1.00
300_N	303_N	0.658	1.00
320_D	323_K	0.652	1.00
132_L	326_I	0.651	1.00
46_A	353_V	0.651	1.00
12_R	46_A	0.649	1.00
14_V	66_T	0.647	1.00
172_V	203_S	0.647	1.00
296_K	300_N	0.645	1.00
245_P	273_M	0.643	1.00
273_M	277_L	0.642	1.00
97_M	130_C	0.642	1.00
269_A	273_M	0.642	1.00
152_I	328_L	0.641	1.00
150_C	187_M	0.640	1.00
237_V	252_L	0.639	1.00
3_T	118_Y	0.638	1.00
180_L	192_I	0.637	1.00
148_M	325_A	0.637	1.00
178_I	262_F	0.634	1.00
5_V	116_A	0.633	1.00
132_L	323_K	0.632	1.00
16_L	346_L	0.632	1.00
265_A	289_G	0.631	1.00
204_R	252_L	0.631	1.00
104_S	280_E	0.630	1.00
218_V	223_P	0.630	1.00
146_E	150_C	0.629	1.00
71_A	90_R	0.627	1.00
284_L	311_V	0.625	1.00
31_V	93_L	0.621	1.00
35_S	343_I	0.620	1.00
155_Y	198_G	0.616	1.00
100_P	124_I	0.615	1.00
220_K	335_Q	0.614	1.00
181_L	277_L	0.613	1.00
141_A	145_A	0.613	1.00
263_V	270_V	0.612	1.00
171_G	310_H	0.611	1.00
29_L	123_E	0.610	1.00
89_Q	136_G	0.609	1.00
45_A	109_Y	0.609	1.00
221_L	338_F	0.609	1.00
12_R	47_L	0.607	1.00
208_V	245_P	0.605	1.00
260_D	285_N	0.604	1.00
273_M	276_E	0.602	1.00
153_G	314_T	0.600	1.00
181_L	273_M	0.600	1.00
213_K	360_P	0.600	1.00
31_V	131_V	0.600	1.00
22_P	118_Y	0.600	1.00
285_N	314_T	0.600	1.00
263_V	289_G	0.595	1.00
258_F	277_L	0.590	1.00
319_T	323_K	0.588	1.00
342_H	351_E	0.587	1.00
174_P	199_G	0.587	1.00
196_I	333_Q	0.586	1.00
95_P	146_E	0.583	1.00
290_P	305_H	0.582	1.00
172_V	260_D	0.582	1.00
253_T	258_F	0.579	1.00
93_L	131_V	0.579	1.00
152_I	194_Y	0.579	1.00
114_G	119_M	0.579	1.00
355_N	358_D	0.577	1.00
136_G	330_A	0.576	1.00
320_D	324_E	0.576	1.00
356_L	364_K	0.576	1.00
152_I	324_E	0.576	1.00
148_M	334_L	0.576	1.00
95_P	316_G	0.576	1.00
175_G	202_P	0.575	1.00
364_K	367_Y	0.572	1.00
189_I	221_L	0.567	1.00
210_I	267_V	0.566	1.00
86_K	136_G	0.565	1.00
243_S	247_Q	0.564	1.00
132_L	322_M	0.563	1.00
16_L	349_V	0.562	1.00
85_Y	123_E	0.562	1.00
174_P	198_G	0.561	1.00
44_K	49_G	0.560	1.00
256_A	279_A	0.560	1.00
3_T	22_P	0.559	1.00
14_V	353_V	0.558	1.00
238_N	244_D	0.558	1.00
195_A	202_P	0.558	1.00
149_C	317_G	0.558	1.00
224_V	236_Y	0.558	1.00
193_D	334_L	0.557	1.00
197_N	334_L	0.555	1.00
8_I	46_A	0.554	1.00
36_D	368_N	0.554	1.00
293_K	296_K	0.553	1.00
37_S	69_E	0.553	1.00
37_S	365_L	0.552	1.00
306_Y	315_S	0.549	1.00
303_N	309_T	0.548	1.00
250_R	253_T	0.548	1.00
148_M	193_D	0.547	1.00
147_P	190_G	0.545	1.00
4_K	16_L	0.543	0.99
183_C	192_I	0.543	0.99
35_S	71_A	0.543	0.99
13_D	350_P	0.543	0.99
206_V	235_V	0.542	0.99
237_V	243_S	0.542	0.99
81_L	123_E	0.540	0.99
155_Y	191_A	0.540	0.99
150_C	287_F	0.539	0.99
297_V	301_F	0.538	0.99
82_T	85_Y	0.537	0.99
145_A	325_A	0.536	0.99
39_C	146_E	0.534	0.99
328_L	332_G	0.534	0.99
250_R	257_G	0.533	0.99
177_N	253_T	0.533	0.99
178_I	260_D	0.531	0.99
22_P	120_I	0.531	0.99
154_A	314_T	0.530	0.99
90_R	138_Y	0.527	0.99
8_I	14_V	0.526	0.99
83_G	133_P	0.526	0.99
37_S	143_S	0.525	0.99
61_N	64_V	0.525	0.99
14_V	46_A	0.523	0.99
77_V	85_Y	0.523	0.99
155_Y	262_F	0.523	0.99
155_Y	172_V	0.522	0.99
33_V	93_L	0.522	0.99
271_V	311_V	0.521	0.99
29_L	81_L	0.521	0.99
173_K	260_D	0.520	0.99
148_M	194_Y	0.520	0.99
97_M	122_P	0.518	0.99
245_P	277_L	0.518	0.99
43_W	356_L	0.518	0.99
188_G	209_D	0.517	0.99
77_V	89_Q	0.517	0.99
139_F	144_L	0.516	0.99
83_G	87_K	0.516	0.99
184_A	218_V	0.513	0.99
74_I	89_Q	0.513	0.99
65_I	116_A	0.512	0.99
250_R	307_N	0.511	0.99
249_L	253_T	0.511	0.99
41_S	68_H	0.510	0.99
92_V	322_M	0.510	0.99
152_I	321_D	0.508	0.99
274_A	278_L	0.508	0.99
8_I	66_T	0.508	0.99
251_A	254_G	0.506	0.99
270_V	274_A	0.505	0.99
181_L	265_A	0.505	0.99
92_V	134_Y	0.504	0.99
324_E	328_L	0.504	0.99
355_N	364_K	0.504	0.99
205_V	224_V	0.503	0.99
180_L	191_A	0.503	0.99
29_L	74_I	0.502	0.99
194_Y	197_N	0.501	0.99
328_L	331_T	0.501	0.99
29_L	77_V	0.501	0.99
38_V	356_L	0.500	0.99
50_S	59_L	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ej6A	1	0.7671	100	0.267	Contact Map
3ukoA	4	0.7765	100	0.271	Contact Map
3ip1A	4	0.7835	100	0.272	Contact Map
3m6iA	4	0.7741	100	0.274	Contact Map
1f8fA	4	0.7671	100	0.277	Contact Map
1p0fA	2	0.7694	100	0.28	Contact Map
1cdoA	2	0.7694	100	0.281	Contact Map
4oh1A	4	0.7788	100	0.281	Contact Map
1e3iA	2	0.7647	100	0.282	Contact Map
4ilkA	2	0.7553	100	0.283	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.012 seconds.