AER - ECOLI - GREMLIN Contacts

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AER - Aerotaxis receptor

UniProt:	P50466	Sequences: MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRARGVMTLMFILLAAMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVAHQALKVATGERNSVEHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQVSAMVKHRASRLEDAVTVLH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12955
Length:	506 (400)
Sequences:	6829 (5914)
Seq/√Len:	295.7

ECOLI - AER MCP3 MCP1 MCP2 MCP4
BACSU - MCPC TLPB TLPA MCPB MCPA YVAQ YOAH TLPC HEMAT
HALSA - Q9HQX8 HTR4 HTR2 Q9HRA1 Q9HR88 COST Q9HP10 Q9HRN6 Q9HPW6 HMAT HTR9 Q9HS86 HTR7 Q9HPA2 Q9HPQ5 Q9HQT5 HTR1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
235_R	240_G	4.957	1.00
327_A	330_G	4.254	1.00
221_K	226_E	3.478	1.00
247_G	250_G	2.859	1.00
343_D	417_K	2.543	1.00
215_V	243_L	2.521	1.00
462_S	465_R	2.515	1.00
220_L	241_L	2.496	1.00
206_W	210_R	2.451	1.00
237_D	240_G	2.409	1.00
230_V	254_R	2.293	1.00
347_S	417_K	2.208	1.00
221_K	229_S	2.145	1.00
205_E	209_V	2.142	1.00
219_A	249_L	2.106	1.00
346_D	349_Q	2.101	1.00
395_H	398_S	2.074	1.00
298_T	302_M	2.031	1.00
308_Q	311_A	2.024	1.00
216_A	245_A	1.999	1.00
332_E	336_T	1.982	1.00
184_A	188_V	1.979	1.00
432_M	435_I	1.970	1.00
340_T	421_G	1.961	1.00
219_A	246_V	1.943	1.00
133_L	136_G	1.912	1.00
350_R	353_T	1.900	1.00
461_S	465_R	1.899	1.00
219_A	245_A	1.872	1.00
352_G	415_A	1.865	1.00
408_R	412_D	1.852	1.00
419_Q	423_Q	1.849	1.00
441_N	444_Q	1.836	1.00
400_S	404_A	1.836	1.00
357_L	403_A	1.823	1.00
181_W	185_A	1.816	1.00
315_A	318_K	1.800	1.00
140_K	144_K	1.794	1.00
341_M	421_G	1.789	1.00
222_V	249_L	1.784	1.00
220_L	248_Q	1.754	1.00
479_E	482_E	1.732	1.00
325_N	329_Q	1.711	1.00
483_E	486_Q	1.706	1.00
347_S	413_A	1.705	1.00
187_V	191_I	1.697	1.00
350_R	406_D	1.696	1.00
188_V	192_L	1.691	1.00
230_V	251_L	1.685	1.00
230_V	247_G	1.671	1.00
348_T	418_V	1.665	1.00
427_A	430_R	1.664	1.00
111_Y	115_R	1.658	1.00
373_A	394_R	1.653	1.00
259_D	497_R	1.645	1.00
215_V	242_T	1.636	1.00
183_V	187_V	1.629	1.00
316_A	320_S	1.624	1.00
220_L	224_T	1.618	1.00
469_E	472_L	1.611	1.00
345_A	422_S	1.601	1.00
426_H	430_R	1.599	1.00
216_A	241_L	1.589	1.00
342_D	346_D	1.576	1.00
402_N	406_D	1.558	1.00
356_S	360_D	1.552	1.00
230_V	250_G	1.545	1.00
290_D	293_Q	1.543	1.00
241_L	244_R	1.539	1.00
354_I	410_L	1.530	1.00
435_I	446_I	1.525	1.00
391_G	394_R	1.518	1.00
430_R	434_D	1.512	1.00
353_T	356_S	1.510	1.00
493_H	497_R	1.505	1.00
398_S	402_N	1.503	1.00
313_A	316_A	1.493	1.00
490_M	493_H	1.489	1.00
412_D	416_D	1.487	1.00
331_G	338_I	1.483	1.00
201_S	205_E	1.483	1.00
479_E	483_E	1.480	1.00
294_Q	297_A	1.478	1.00
222_V	250_G	1.470	1.00
316_A	327_A	1.469	1.00
220_L	245_A	1.447	1.00
451_H	454_L	1.418	1.00
121_E	125_A	1.416	1.00
121_E	129_L	1.416	1.00
279_D	283_E	1.407	1.00
373_A	391_G	1.404	1.00
163_W	166_R	1.404	1.00
316_A	330_G	1.401	1.00
290_D	294_Q	1.397	1.00
259_D	501_A	1.379	1.00
132_A	137_R	1.377	1.00
440_K	444_Q	1.370	1.00
185_A	188_V	1.366	1.00
217_H	220_L	1.360	1.00
219_A	242_T	1.356	1.00
316_A	446_I	1.355	1.00
482_E	486_Q	1.353	1.00
215_V	246_V	1.351	1.00
322_T	325_N	1.342	1.00
442_V	446_I	1.342	1.00
269_N	273_T	1.337	1.00
110_G	116_T	1.334	1.00
301_Q	304_A	1.331	1.00
454_L	458_D	1.330	1.00
433_E	437_A	1.330	1.00
133_L	137_R	1.329	1.00
132_A	135_A	1.319	1.00
211_P	238_E	1.318	1.00
402_N	405_N	1.305	1.00
120_D	123_I	1.305	1.00
299_M	302_M	1.304	1.00
458_D	462_S	1.304	1.00
343_D	346_D	1.303	1.00
428_A	432_M	1.302	1.00
273_T	276_K	1.302	1.00
340_T	420_S	1.301	1.00
497_R	500_D	1.300	1.00
215_V	219_A	1.300	1.00
233_L	244_R	1.299	1.00
254_R	258_N	1.298	1.00
320_S	330_G	1.292	1.00
409_K	413_A	1.291	1.00
276_K	280_E	1.290	1.00
246_V	250_G	1.286	1.00
126_V	130_Y	1.284	1.00
260_V	502_V	1.283	1.00
346_D	350_R	1.283	1.00
359_N	408_R	1.277	1.00
300_N	304_A	1.273	1.00
123_I	126_V	1.272	1.00
259_D	262_S	1.267	1.00
468_D	472_L	1.261	1.00
430_R	433_E	1.259	1.00
127_E	130_Y	1.258	1.00
317_D	320_S	1.246	1.00
233_L	243_L	1.245	1.00
321_I	325_N	1.243	1.00
332_E	335_T	1.240	1.00
280_E	283_E	1.239	1.00
314_S	318_K	1.236	1.00
344_I	414_S	1.236	1.00
132_A	136_G	1.232	1.00
226_E	229_S	1.231	1.00
146_L	150_K	1.230	1.00
339_K	343_D	1.222	1.00
162_R	166_R	1.222	1.00
337_V	425_V	1.218	1.00
233_L	247_G	1.209	1.00
347_S	350_R	1.207	1.00
318_K	321_I	1.206	1.00
349_Q	419_Q	1.206	1.00
309_N	453_T	1.203	1.00
405_N	409_K	1.197	1.00
125_A	129_L	1.195	1.00
184_A	187_V	1.194	1.00
213_E	216_A	1.193	1.00
323_A	330_G	1.192	1.00
339_K	342_D	1.189	1.00
151_G	155_K	1.185	1.00
318_K	322_T	1.178	1.00
115_R	118_A	1.177	1.00
342_D	345_A	1.175	1.00
246_V	249_L	1.169	1.00
197_V	201_S	1.164	1.00
437_A	441_N	1.161	1.00
269_N	272_E	1.156	1.00
360_D	363_F	1.154	1.00
340_T	424_Q	1.152	1.00
333_A	336_T	1.148	1.00
161_L	164_R	1.148	1.00
247_G	251_L	1.140	1.00
251_L	255_W	1.140	1.00
122_E	126_V	1.139	1.00
172_M	176_L	1.138	1.00
134_N	138_T	1.137	1.00
382_Q	393_V	1.132	1.00
462_S	466_A	1.129	1.00
199_L	203_C	1.128	1.00
179_M	183_V	1.128	1.00
333_A	338_I	1.127	1.00
283_E	287_Q	1.122	1.00
180_L	184_A	1.120	1.00
344_I	421_G	1.117	1.00
168_V	171_L	1.116	1.00
119_T	123_I	1.115	1.00
209_V	213_E	1.114	1.00
324_S	328_V	1.114	1.00
191_I	195_L	1.112	1.00
221_K	249_L	1.111	1.00
463_L	467_V	1.109	1.00
348_T	414_S	1.104	1.00
341_M	422_S	1.097	1.00
252_M	504_V	1.095	1.00
262_S	266_S	1.088	1.00
208_I	211_P	1.087	1.00
211_P	240_G	1.084	1.00
278_T	481_V	1.084	1.00
243_L	247_G	1.079	1.00
216_A	220_L	1.076	1.00
250_G	254_R	1.076	1.00
405_N	408_R	1.075	1.00
218_Q	246_V	1.070	1.00
307_K	311_A	1.064	1.00
284_H	473_I	1.060	1.00
255_W	259_D	1.060	1.00
231_E	247_G	1.059	1.00
413_A	417_K	1.056	1.00
434_D	437_A	1.053	1.00
501_A	504_V	1.052	1.00
118_A	130_Y	1.050	1.00
211_P	235_R	1.048	1.00
133_L	138_T	1.047	1.00
180_L	183_V	1.046	1.00
283_E	286_Q	1.046	1.00
214_N	217_H	1.040	1.00
166_R	170_T	1.038	1.00
218_Q	231_E	1.036	1.00
227_R	253_C	1.031	1.00
326_A	434_D	1.031	1.00
343_D	347_S	1.022	1.00
444_Q	447_A	1.021	1.00
341_M	425_V	1.021	1.00
144_K	148_V	1.021	1.00
336_T	339_K	1.020	1.00
271_S	488_S	1.019	1.00
476_K	479_E	1.009	1.00
326_A	330_G	1.006	1.00
496_S	500_D	1.002	1.00
345_A	419_Q	1.001	1.00
334_M	338_I	0.997	1.00
418_V	421_G	0.993	1.00
265_S	269_N	0.992	1.00
163_W	171_L	0.987	1.00
475_Q	479_E	0.986	1.00
335_T	339_K	0.986	1.00
169_M	173_F	0.985	1.00
161_L	165_A	0.985	1.00
239_L	243_L	0.983	1.00
222_V	246_V	0.979	1.00
202_A	206_W	0.977	1.00
216_A	242_T	0.977	1.00
304_A	308_Q	0.977	1.00
144_K	147_V	0.974	1.00
214_N	218_Q	0.972	1.00
316_A	324_S	0.969	1.00
272_E	492_K	0.965	1.00
479_E	486_Q	0.961	1.00
148_V	151_G	0.960	1.00
146_L	155_K	0.959	1.00
150_K	155_K	0.958	1.00
132_A	138_T	0.954	1.00
302_M	306_V	0.952	1.00
473_I	477_N	0.951	1.00
287_Q	290_D	0.949	1.00
135_A	138_T	0.947	1.00
299_M	305_S	0.945	1.00
248_Q	251_L	0.944	1.00
498_L	505_L	0.942	1.00
437_A	440_K	0.940	1.00
455_E	458_D	0.937	1.00
214_N	232_H	0.935	1.00
146_L	151_G	0.935	1.00
298_T	301_Q	0.933	1.00
456_Q	463_L	0.930	1.00
252_M	255_W	0.924	1.00
486_Q	490_M	0.923	1.00
345_A	349_Q	0.923	1.00
118_A	123_I	0.922	1.00
314_S	454_L	0.921	1.00
369_A	394_R	0.919	1.00
406_D	409_K	0.917	1.00
363_F	374_V	0.916	1.00
115_R	121_E	0.916	1.00
291_N	469_E	0.912	1.00
453_T	456_Q	0.912	1.00
324_S	327_A	0.911	1.00
472_L	476_K	0.910	1.00
272_E	276_K	0.908	1.00
292_V	295_T	0.907	1.00
444_Q	448_Q	0.907	1.00
233_L	237_D	0.906	1.00
112_M	115_R	0.905	1.00
260_V	498_L	0.902	1.00
447_A	451_H	0.900	1.00
162_R	165_A	0.899	1.00
320_S	327_A	0.898	1.00
134_N	137_R	0.897	1.00
288_T	302_M	0.896	1.00
499_E	503_T	0.893	1.00
432_M	446_I	0.893	1.00
297_A	301_Q	0.891	1.00
327_A	436_V	0.891	1.00
122_E	125_A	0.891	1.00
118_A	126_V	0.890	1.00
173_F	177_A	0.885	1.00
248_Q	252_M	0.881	1.00
458_D	461_S	0.880	1.00
193_C	197_V	0.876	1.00
329_Q	427_A	0.874	1.00
135_A	140_K	0.871	1.00
461_S	464_T	0.870	1.00
493_H	496_S	0.865	1.00
106_G	110_G	0.861	1.00
401_A	405_N	0.861	1.00
219_A	222_V	0.857	1.00
143_H	147_V	0.857	1.00
421_G	425_V	0.854	1.00
310_S	313_A	0.854	1.00
400_S	410_L	0.854	1.00
150_K	154_G	0.853	1.00
297_A	300_N	0.851	1.00
421_G	424_Q	0.849	1.00
170_T	174_I	0.847	1.00
300_N	464_T	0.842	1.00
262_S	265_S	0.839	1.00
356_S	359_N	0.839	1.00
198_L	202_A	0.837	1.00
435_I	442_V	0.836	1.00
302_M	309_N	0.835	1.00
226_E	506_H	0.831	1.00
391_G	395_H	0.826	1.00
311_A	315_A	0.825	1.00
146_L	149_R	0.822	1.00
171_L	175_L	0.818	1.00
350_R	413_A	0.817	1.00
489_A	493_H	0.817	1.00
212_I	242_T	0.816	1.00
455_E	459_G	0.815	1.00
118_A	121_E	0.814	1.00
123_I	127_E	0.812	1.00
276_K	279_D	0.812	1.00
175_L	179_M	0.811	1.00
213_E	217_H	0.811	1.00
235_R	238_E	0.809	1.00
432_M	456_Q	0.806	1.00
399_R	402_N	0.805	1.00
353_T	357_L	0.804	1.00
111_Y	116_T	0.803	1.00
451_H	455_E	0.802	1.00
145_G	149_R	0.802	1.00
426_H	429_G	0.801	1.00
225_G	249_L	0.800	1.00
359_N	404_A	0.795	0.99
354_I	403_A	0.795	0.99
119_T	122_E	0.793	0.99
268_R	492_K	0.793	0.99
177_A	181_W	0.791	0.99
108_I	115_R	0.788	0.99
354_I	411_I	0.785	0.99
261_S	265_S	0.785	0.99
431_T	435_I	0.783	0.99
216_A	239_L	0.783	0.99
211_P	239_L	0.783	0.99
217_H	221_K	0.777	0.99
397_A	400_S	0.777	0.99
274_L	488_S	0.774	0.99
163_W	182_F	0.772	0.99
343_D	420_S	0.772	0.99
242_T	249_L	0.771	0.99
329_Q	434_D	0.769	0.99
159_L	164_R	0.764	0.99
231_E	243_L	0.764	0.99
225_G	256_L	0.763	0.99
354_I	357_L	0.761	0.99
224_T	248_Q	0.760	0.99
441_N	445_L	0.760	0.99
165_A	171_L	0.759	0.99
273_T	483_E	0.758	0.99
299_M	306_V	0.757	0.99
311_A	314_S	0.757	0.99
338_I	429_G	0.757	0.99
163_W	170_T	0.756	0.99
400_S	411_I	0.752	0.99
366_N	394_R	0.752	0.99
218_Q	229_S	0.749	0.99
249_L	253_C	0.748	0.99
359_N	363_F	0.748	0.99
330_G	435_I	0.748	0.99
195_L	199_L	0.745	0.99
280_E	284_H	0.744	0.99
414_S	418_V	0.743	0.99
331_G	335_T	0.742	0.99
284_H	288_T	0.742	0.99
209_V	239_L	0.738	0.99
312_T	316_A	0.736	0.99
399_R	406_D	0.735	0.99
500_D	504_V	0.734	0.99
225_G	242_T	0.731	0.99
348_T	354_I	0.730	0.99
333_A	424_Q	0.729	0.99
307_K	461_S	0.727	0.99
354_I	404_A	0.727	0.99
113_S	116_T	0.725	0.99
203_C	206_W	0.722	0.99
126_V	129_L	0.721	0.99
320_S	323_A	0.721	0.99
373_A	399_R	0.720	0.99
448_Q	451_H	0.719	0.99
288_T	291_N	0.715	0.99
152_W	155_K	0.715	0.99
143_H	146_L	0.715	0.99
265_S	499_E	0.713	0.99
359_N	401_A	0.711	0.99
124_A	128_P	0.710	0.99
264_V	268_R	0.708	0.99
221_K	224_T	0.706	0.99
416_D	420_S	0.706	0.99
432_M	445_L	0.705	0.99
268_R	499_E	0.704	0.99
286_Q	290_D	0.704	0.99
363_F	367_I	0.703	0.99
145_G	151_G	0.700	0.99
287_Q	291_N	0.699	0.99
350_R	410_L	0.698	0.99
238_E	241_L	0.691	0.99
456_Q	459_G	0.691	0.99
486_Q	489_A	0.688	0.99
369_A	373_A	0.687	0.98
125_A	130_Y	0.687	0.98
292_V	470_L	0.687	0.98
121_E	128_P	0.686	0.98
117_R	120_D	0.682	0.98
222_V	227_R	0.681	0.98
145_G	150_K	0.680	0.98
124_A	127_E	0.680	0.98
309_N	316_A	0.677	0.98
481_V	484_S	0.675	0.98
110_G	115_R	0.675	0.98
149_R	153_L	0.672	0.98
411_I	415_A	0.672	0.98
165_A	168_V	0.671	0.98
291_N	294_Q	0.669	0.98
319_L	323_A	0.668	0.98
293_Q	471_N	0.667	0.98
316_A	323_A	0.666	0.98
115_R	130_Y	0.664	0.98
209_V	216_A	0.662	0.98
367_I	374_V	0.661	0.98
166_R	169_M	0.660	0.98
394_R	398_S	0.660	0.98
484_S	487_V	0.660	0.98
222_V	253_C	0.659	0.98
325_N	328_V	0.659	0.98
229_S	250_G	0.659	0.98
120_D	124_A	0.658	0.98
329_Q	332_E	0.655	0.98
121_E	124_A	0.655	0.98
210_R	214_N	0.654	0.98
331_G	337_V	0.648	0.98
323_A	327_A	0.646	0.98
146_L	153_L	0.646	0.98
277_G	480_L	0.645	0.98
304_A	307_K	0.645	0.98
147_V	151_G	0.643	0.98
477_N	481_V	0.641	0.98
118_A	125_A	0.639	0.98
261_S	499_E	0.639	0.98
264_V	499_E	0.639	0.98
359_N	405_N	0.636	0.98
333_A	337_V	0.636	0.98
472_L	475_Q	0.635	0.97
496_S	499_E	0.635	0.97
263_Q	266_S	0.634	0.97
181_W	184_A	0.633	0.97
443_T	446_I	0.632	0.97
442_V	456_Q	0.632	0.97
106_G	116_T	0.631	0.97
176_L	179_M	0.630	0.97
302_M	313_A	0.629	0.97
298_T	309_N	0.629	0.97
199_L	202_A	0.624	0.97
344_I	418_V	0.618	0.97
500_D	503_T	0.617	0.97
459_G	463_L	0.616	0.97
218_Q	221_K	0.616	0.97
357_L	397_A	0.612	0.97
118_A	128_P	0.612	0.97
420_S	423_Q	0.611	0.97
294_Q	462_S	0.610	0.97
258_N	262_S	0.608	0.97
460_L	464_T	0.608	0.97
355_T	408_R	0.605	0.97
464_T	468_D	0.602	0.97
132_A	140_K	0.600	0.96
173_F	176_L	0.597	0.96
412_D	415_A	0.595	0.96
171_L	174_I	0.595	0.96
369_A	393_V	0.594	0.96
268_R	272_E	0.594	0.96
134_N	140_K	0.594	0.96
459_G	462_S	0.594	0.96
326_A	329_Q	0.591	0.96
291_N	298_T	0.590	0.96
302_M	460_L	0.590	0.96
351_I	414_S	0.589	0.96
113_S	130_Y	0.587	0.96
298_T	459_G	0.585	0.96
313_A	327_A	0.584	0.96
140_K	143_H	0.583	0.96
266_S	490_M	0.582	0.96
467_V	471_N	0.582	0.96
113_S	118_A	0.582	0.96
203_C	207_Q	0.580	0.96
409_K	412_D	0.580	0.96
148_V	152_W	0.579	0.96
327_A	429_G	0.579	0.96
151_G	154_G	0.579	0.96
428_A	431_T	0.578	0.96
303_A	460_L	0.577	0.96
281_L	285_T	0.575	0.96
282_N	478_A	0.575	0.96
141_R	144_K	0.575	0.96
331_G	436_V	0.574	0.95
185_A	189_T	0.574	0.95
267_V	491_V	0.572	0.95
211_P	242_T	0.570	0.95
310_S	450_S	0.569	0.95
189_T	193_C	0.569	0.95
111_Y	114_I	0.569	0.95
140_K	145_G	0.568	0.95
192_L	196_V	0.567	0.95
341_M	345_A	0.567	0.95
344_I	354_I	0.566	0.95
157_P	164_R	0.565	0.95
446_I	450_S	0.565	0.95
457_A	460_L	0.565	0.95
271_S	495_A	0.562	0.95
131_K	135_A	0.562	0.95
288_T	456_Q	0.561	0.95
281_L	481_V	0.561	0.95
192_L	199_L	0.561	0.95
141_R	145_G	0.561	0.95
474_T	478_A	0.560	0.95
469_E	473_I	0.560	0.95
355_T	359_N	0.559	0.95
138_T	142_I	0.559	0.95
244_R	247_G	0.559	0.95
435_I	439_V	0.556	0.95
159_L	163_W	0.554	0.95
164_R	168_V	0.553	0.95
415_A	419_Q	0.553	0.95
218_Q	243_L	0.551	0.94
159_L	162_R	0.550	0.94
491_V	495_A	0.550	0.94
237_D	243_L	0.549	0.94
260_V	264_V	0.546	0.94
291_N	466_A	0.544	0.94
357_L	411_I	0.544	0.94
186_P	190_Y	0.541	0.94
320_S	326_A	0.539	0.94
152_W	156_L	0.538	0.94
305_S	308_Q	0.537	0.94
136_G	139_S	0.537	0.94
141_R	147_V	0.537	0.94
148_V	155_K	0.537	0.94
110_G	165_A	0.536	0.94
439_V	446_I	0.535	0.93
176_L	180_L	0.534	0.93
466_A	469_E	0.532	0.93
260_V	263_Q	0.529	0.93
428_A	435_I	0.526	0.93
316_A	445_L	0.526	0.93
108_I	111_Y	0.525	0.93
235_R	243_L	0.525	0.93
353_T	406_D	0.524	0.93
111_Y	118_A	0.523	0.93
121_E	130_Y	0.522	0.93
303_A	464_T	0.519	0.92
159_L	166_R	0.519	0.92
118_A	122_E	0.519	0.92
418_V	422_S	0.518	0.92
113_S	117_R	0.517	0.92
449_I	456_Q	0.517	0.92
236_S	240_G	0.515	0.92
459_G	467_V	0.513	0.92
227_R	249_L	0.513	0.92
269_N	276_K	0.512	0.92
444_Q	451_H	0.512	0.92
232_H	247_G	0.512	0.92
316_A	319_L	0.512	0.92
148_V	153_L	0.509	0.92
298_T	463_L	0.509	0.92
303_A	306_V	0.508	0.92
429_G	432_M	0.507	0.92
243_L	246_V	0.506	0.92
243_L	249_L	0.505	0.91
436_V	440_K	0.504	0.91
373_A	384_K	0.503	0.91
293_Q	297_A	0.503	0.91
223_A	245_A	0.502	0.91
136_G	140_K	0.502	0.91
322_T	326_A	0.501	0.91
145_G	152_W	0.500	0.91
358_I	400_S	0.500	0.91
298_T	316_A	0.500	0.91

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.5949	100	0.389	Contact Map
1qu7A	2	0.4407	100	0.516	Contact Map
2ch7A	2	0.5494	100	0.556	Contact Map
3g67A	2	0.4209	100	0.611	Contact Map
4i3mA	2	0.2905	99.9	0.754	Contact Map
3volA	2	0.247	99.7	0.835	Contact Map
4cq4A	4	0.17	99.5	0.849	Contact Map
2gj3A	7	0.2352	99.5	0.855	Contact Map
3lyxA	2	0.2352	99.5	0.857	Contact Map
2f95B	2	0.1047	99.5	0.857	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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