MLC - ECOLI - GREMLIN Contacts

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MLC - Protein mlc

UniProt:	P50456	Sequences: MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAPASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALRDLSSKLVVEESQELALKDDLPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTENGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQVVIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILELAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFNPQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKDAMYNGSLLIRLLQG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13156
Length:	406 (368)
Sequences:	7220 (5299)
Seq/√Len:	276.2

ECOLI - MLC NAGC YPHH MAK NAGK NANK ALSK
BACSU - XYLR GLK SCRK
HALSA - Q9HMA7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
103_D	107_K	3.744	1.00
111_E	381_Q	3.393	1.00
193_Q	236_H	3.272	1.00
177_P	180_E	3.270	1.00
148_S	391_K	2.968	1.00
61_Q	81_E	2.898	1.00
217_Q	341_G	2.875	1.00
158_D	161_N	2.809	1.00
102_R	388_A	2.777	1.00
216_I	329_M	2.644	1.00
257_C	264_C	2.563	1.00
88_L	132_I	2.550	1.00
149_I	186_T	2.548	1.00
259_C	264_C	2.540	1.00
239_S	334_N	2.441	1.00
277_L	317_G	2.434	1.00
248_T	328_I	2.404	1.00
100_A	384_M	2.394	1.00
179_G	183_E	2.365	1.00
25_I	31_V	2.340	1.00
61_Q	79_V	2.330	1.00
126_D	185_H	2.315	1.00
129_I	185_H	2.314	1.00
265_L	325_I	2.254	1.00
99_L	131_H	2.206	1.00
337_K	374_E	2.146	1.00
212_A	337_K	2.133	1.00
319_G	323_G	2.115	1.00
209_S	215_V	2.060	1.00
112_E	134_Q	2.059	1.00
320_A	358_S	2.057	1.00
326_L	338_I	2.018	1.00
89_S	384_M	2.008	1.00
316_T	354_V	1.995	1.00
99_L	135_F	1.994	1.00
25_I	60_V	1.991	1.00
112_E	138_R	1.961	1.00
180_E	184_Q	1.954	1.00
256_R	262_H	1.937	1.00
151_I	182_L	1.922	1.00
230_T	235_L	1.914	1.00
68_A	71_R	1.902	1.00
21_V	36_L	1.850	1.00
218_V	326_L	1.825	1.00
133_D	185_H	1.811	1.00
356_S	360_R	1.807	1.00
193_Q	198_A	1.793	1.00
323_G	358_S	1.785	1.00
206_F	389_L	1.772	1.00
213_R	336_Q	1.750	1.00
18_A	57_A	1.749	1.00
55_L	62_E	1.747	1.00
319_G	355_I	1.742	1.00
200_T	229_I	1.739	1.00
181_A	184_Q	1.730	1.00
152_T	198_A	1.718	1.00
214_D	336_Q	1.703	1.00
63_L	79_V	1.693	1.00
18_A	53_E	1.687	1.00
193_Q	197_S	1.682	1.00
51_V	60_V	1.669	1.00
247_H	257_C	1.669	1.00
149_I	188_V	1.668	1.00
257_C	260_G	1.656	1.00
238_G	336_Q	1.653	1.00
324_R	328_I	1.641	1.00
88_L	146_L	1.624	1.00
200_T	227_G	1.624	1.00
352_F	356_S	1.608	1.00
86_H	109_V	1.603	1.00
110_V	138_R	1.598	1.00
199_W	217_Q	1.597	1.00
247_H	259_C	1.596	1.00
359_I	373_V	1.576	1.00
249_Q	328_I	1.569	1.00
296_T	299_S	1.552	1.00
194_H	244_E	1.545	1.00
146_L	188_V	1.536	1.00
213_R	231_D	1.530	1.00
357_D	361_Q	1.521	1.00
215_V	229_I	1.521	1.00
110_V	135_F	1.514	1.00
62_E	76_V	1.502	1.00
28_L	39_L	1.492	1.00
302_Q	306_R	1.485	1.00
304_A	315_I	1.485	1.00
90_L	128_I	1.474	1.00
349_D	353_P	1.470	1.00
337_K	372_S	1.469	1.00
224_V	269_A	1.468	1.00
87_Y	392_D	1.458	1.00
247_H	264_C	1.449	1.00
129_I	186_T	1.434	1.00
176_M	181_A	1.421	1.00
305_L	350_I	1.412	1.00
36_L	47_I	1.407	1.00
319_G	354_V	1.401	1.00
278_A	314_I	1.398	1.00
277_L	280_L	1.393	1.00
101_L	135_F	1.388	1.00
51_V	78_L	1.376	1.00
90_L	132_I	1.376	1.00
142_K	145_R	1.373	1.00
35_D	38_R	1.371	1.00
85_W	147_T	1.353	1.00
303_A	308_D	1.351	1.00
212_A	336_Q	1.348	1.00
200_T	215_V	1.345	1.00
358_S	362_Q	1.339	1.00
96_E	113_S	1.336	1.00
354_V	357_D	1.316	1.00
90_L	99_L	1.314	1.00
274_I	318_V	1.298	1.00
83_E	103_D	1.291	1.00
55_L	78_L	1.286	1.00
205_L	393_A	1.275	1.00
133_D	186_T	1.274	1.00
100_A	108_L	1.269	1.00
260_G	264_C	1.267	1.00
24_L	31_V	1.260	1.00
299_S	302_Q	1.244	1.00
255_K	276_E	1.244	1.00
358_S	361_Q	1.242	1.00
122_L	181_A	1.242	1.00
329_M	332_L	1.241	1.00
348_A	352_F	1.240	1.00
298_D	302_Q	1.239	1.00
198_A	387_A	1.233	1.00
24_L	39_L	1.233	1.00
152_T	383_T	1.223	1.00
98_F	113_S	1.213	1.00
255_K	267_T	1.211	1.00
202_A	378_F	1.193	1.00
182_L	190_V	1.192	1.00
156_I	167_M	1.188	1.00
112_E	131_H	1.180	1.00
134_Q	138_R	1.178	1.00
330_V	359_I	1.176	1.00
203_E	207_G	1.176	1.00
354_V	358_S	1.175	1.00
352_F	375_S	1.170	1.00
215_V	339_L	1.169	1.00
133_D	143_L	1.169	1.00
33_R	78_L	1.165	1.00
255_K	268_I	1.153	1.00
89_S	387_A	1.137	1.00
131_H	134_Q	1.130	1.00
18_A	50_I	1.127	1.00
114_Q	131_H	1.124	1.00
125_L	181_A	1.119	1.00
281_R	313_D	1.113	1.00
177_P	181_A	1.109	1.00
237_A	243_V	1.106	1.00
194_H	223_N	1.105	1.00
330_V	338_I	1.101	1.00
126_D	130_S	1.081	1.00
35_D	39_L	1.080	1.00
277_L	281_R	1.080	1.00
114_Q	134_Q	1.079	1.00
62_E	78_L	1.076	1.00
277_L	314_I	1.073	1.00
204_A	215_V	1.062	1.00
255_K	277_L	1.062	1.00
66_K	75_A	1.062	1.00
216_I	226_A	1.059	1.00
278_A	311_A	1.059	1.00
23_R	27_Q	1.053	1.00
30_P	79_V	1.053	1.00
231_D	235_L	1.050	1.00
197_S	234_L	1.046	1.00
214_D	231_D	1.045	1.00
20_A	40_A	1.044	1.00
237_A	242_L	1.044	1.00
21_V	47_I	1.041	1.00
31_V	39_L	1.038	1.00
247_H	260_G	1.038	1.00
216_I	228_V	1.037	1.00
102_R	108_L	1.028	1.00
120_D	123_P	1.025	1.00
133_D	137_I	1.019	1.00
89_S	150_A	1.018	1.00
22_Y	80_V	1.016	1.00
163_I	175_E	1.016	1.00
183_E	187_G	1.013	1.00
281_R	314_I	1.012	1.00
87_Y	391_K	1.009	1.00
316_T	357_D	1.009	1.00
252_P	324_R	1.008	1.00
141_K	145_R	1.008	1.00
124_L	173_V	1.008	1.00
64_E	77_G	0.997	1.00
278_A	282_L	0.995	1.00
223_N	244_E	0.991	1.00
181_A	185_H	0.984	1.00
33_R	62_E	0.981	1.00
299_S	303_A	0.979	1.00
196_I	219_V	0.978	1.00
228_V	235_L	0.975	1.00
204_A	229_I	0.972	1.00
220_I	322_V	0.970	1.00
353_P	356_S	0.968	1.00
44_P	48_T	0.966	1.00
183_E	190_V	0.966	1.00
121_D	173_V	0.965	1.00
163_I	177_P	0.964	1.00
235_L	333_F	0.963	1.00
304_A	312_K	0.963	1.00
82_T	105_S	0.961	1.00
86_H	141_K	0.957	1.00
304_A	350_I	0.952	1.00
302_Q	305_L	0.948	1.00
340_I	345_S	0.946	1.00
228_V	333_F	0.942	1.00
330_V	371_I	0.942	1.00
187_G	190_V	0.941	1.00
24_L	40_A	0.936	1.00
353_P	357_D	0.936	1.00
88_L	136_F	0.933	1.00
251_D	268_I	0.930	1.00
101_L	139_H	0.930	1.00
264_C	267_T	0.928	1.00
348_A	375_S	0.917	1.00
86_H	145_R	0.916	1.00
191_Y	394_M	0.915	1.00
323_G	327_A	0.915	1.00
108_L	111_E	0.914	1.00
191_Y	391_K	0.914	1.00
150_A	198_A	0.910	1.00
58_H	81_E	0.908	1.00
324_R	362_Q	0.906	1.00
274_I	300_L	0.901	1.00
129_I	133_D	0.899	1.00
312_K	316_T	0.898	1.00
114_Q	127_R	0.896	1.00
257_C	263_G	0.895	1.00
121_D	176_M	0.893	1.00
173_V	176_M	0.889	1.00
212_A	215_V	0.887	1.00
88_L	149_I	0.887	1.00
277_L	318_V	0.884	1.00
90_L	149_I	0.882	1.00
25_I	36_L	0.882	1.00
198_A	390_V	0.881	1.00
199_W	341_G	0.879	1.00
87_Y	102_R	0.877	1.00
203_E	378_F	0.871	1.00
379_S	382_G	0.871	1.00
199_W	383_T	0.871	1.00
251_D	255_K	0.871	1.00
339_L	376_T	0.870	1.00
150_A	391_K	0.868	1.00
55_L	60_V	0.868	1.00
204_A	232_G	0.859	1.00
278_A	300_L	0.858	1.00
66_K	71_R	0.858	1.00
349_D	375_S	0.854	1.00
114_Q	130_S	0.854	1.00
30_P	77_G	0.854	1.00
34_I	75_A	0.854	1.00
193_Q	390_V	0.850	1.00
88_L	101_L	0.850	1.00
136_F	146_L	0.849	1.00
323_G	359_I	0.849	1.00
320_A	354_V	0.848	1.00
52_R	56_E	0.844	1.00
98_F	111_E	0.844	1.00
130_S	134_Q	0.844	1.00
255_K	280_L	0.841	1.00
261_N	362_Q	0.841	1.00
218_V	245_I	0.841	1.00
129_I	182_L	0.840	1.00
135_F	139_H	0.834	1.00
274_I	314_I	0.832	1.00
195_D	225_G	0.831	1.00
210_R	377_Q	0.831	1.00
282_L	295_L	0.831	1.00
378_F	382_G	0.828	1.00
249_Q	252_P	0.827	1.00
123_P	126_D	0.826	0.99
117_A	127_R	0.826	0.99
214_D	238_G	0.824	0.99
214_D	230_T	0.823	0.99
339_L	374_E	0.821	0.99
196_I	227_G	0.820	0.99
249_Q	261_N	0.820	0.99
127_R	131_H	0.819	0.99
279_Q	293_Q	0.816	0.99
205_L	389_L	0.816	0.99
59_L	84_A	0.815	0.99
225_G	244_E	0.814	0.99
257_C	267_T	0.811	0.99
179_G	192_I	0.801	0.99
42_L	47_I	0.800	0.99
276_E	280_L	0.796	0.99
223_N	266_E	0.795	0.99
305_L	349_D	0.794	0.99
132_I	149_I	0.792	0.99
61_Q	82_T	0.791	0.99
316_T	358_S	0.790	0.99
92_I	97_I	0.787	0.99
207_G	210_R	0.785	0.99
26_D	80_V	0.784	0.99
213_R	232_G	0.779	0.99
197_S	227_G	0.774	0.99
304_A	307_G	0.773	0.99
162_G	177_P	0.770	0.99
251_D	254_G	0.770	0.99
326_L	359_I	0.769	0.99
310_L	313_D	0.769	0.99
259_C	263_G	0.767	0.99
110_V	139_H	0.765	0.99
214_D	235_L	0.765	0.99
320_A	324_R	0.761	0.99
79_V	105_S	0.760	0.99
194_H	225_G	0.759	0.99
331_N	364_L	0.758	0.99
317_G	321_H	0.757	0.99
275_L	297_V	0.757	0.99
237_A	334_N	0.754	0.99
44_P	49_K	0.753	0.99
301_C	305_L	0.753	0.99
153_L	164_V	0.752	0.99
87_Y	147_T	0.751	0.99
304_A	311_A	0.748	0.99
376_T	382_G	0.748	0.99
153_L	157_I	0.745	0.99
97_I	116_L	0.745	0.99
261_N	264_C	0.745	0.99
254_G	268_I	0.744	0.99
301_C	315_I	0.744	0.99
122_L	126_D	0.744	0.99
28_L	31_V	0.742	0.99
322_V	355_I	0.742	0.99
334_N	371_I	0.741	0.99
25_I	78_L	0.740	0.99
309_L	313_D	0.738	0.99
281_R	310_L	0.738	0.99
207_G	211_G	0.737	0.99
265_L	318_V	0.733	0.99
313_D	316_T	0.732	0.99
125_L	178_L	0.732	0.99
323_G	362_Q	0.731	0.99
103_D	109_V	0.731	0.99
346_K	380_N	0.730	0.99
200_T	217_Q	0.727	0.99
228_V	243_V	0.726	0.99
34_I	38_R	0.725	0.99
260_G	263_G	0.723	0.99
100_A	111_E	0.722	0.99
352_F	355_I	0.718	0.99
275_L	300_L	0.714	0.99
203_E	376_T	0.714	0.99
351_L	354_V	0.713	0.99
167_M	170_Y	0.713	0.99
127_R	130_S	0.712	0.99
242_L	334_N	0.708	0.98
158_D	165_H	0.707	0.98
136_F	143_L	0.705	0.98
182_L	186_T	0.704	0.98
21_V	50_I	0.704	0.98
248_T	325_I	0.703	0.98
97_I	114_Q	0.701	0.98
348_A	353_P	0.701	0.98
24_L	36_L	0.699	0.98
102_R	385_A	0.697	0.98
20_A	24_L	0.695	0.98
303_A	306_R	0.692	0.98
247_H	263_G	0.690	0.98
156_I	241_S	0.689	0.98
301_C	304_A	0.682	0.98
91_R	383_T	0.681	0.98
212_A	372_S	0.681	0.98
371_I	375_S	0.677	0.98
308_D	311_A	0.674	0.98
221_D	343_P	0.673	0.98
199_W	382_G	0.672	0.98
268_I	321_H	0.671	0.98
223_N	246_G	0.671	0.98
125_L	176_M	0.669	0.98
220_I	344_L	0.668	0.98
81_E	84_A	0.667	0.98
279_Q	282_L	0.666	0.98
101_L	146_L	0.666	0.98
238_G	334_N	0.664	0.98
162_G	179_G	0.663	0.98
316_T	319_G	0.661	0.98
319_G	358_S	0.660	0.98
319_G	351_L	0.660	0.98
101_L	110_V	0.659	0.98
321_H	325_I	0.659	0.98
108_L	385_A	0.659	0.98
216_I	338_I	0.659	0.98
282_L	310_L	0.655	0.97
155_G	266_E	0.655	0.97
320_A	357_D	0.649	0.97
250_V	265_L	0.648	0.97
86_H	101_L	0.647	0.97
24_L	28_L	0.646	0.97
349_D	356_S	0.644	0.97
208_A	377_Q	0.642	0.97
98_F	384_M	0.641	0.97
197_S	244_E	0.641	0.97
93_S	343_P	0.640	0.97
180_E	183_E	0.639	0.97
136_F	139_H	0.638	0.97
82_T	107_K	0.637	0.97
245_I	332_L	0.637	0.97
99_L	114_Q	0.635	0.97
249_Q	362_Q	0.635	0.97
203_E	377_Q	0.632	0.97
250_V	325_I	0.631	0.97
206_F	385_A	0.631	0.97
112_E	135_F	0.630	0.97
32_S	75_A	0.630	0.97
259_C	267_T	0.629	0.97
195_D	219_V	0.628	0.97
303_A	311_A	0.624	0.97
208_A	339_L	0.621	0.96
83_E	109_V	0.621	0.96
194_H	197_S	0.618	0.96
43_A	46_S	0.617	0.96
313_D	317_G	0.617	0.96
208_A	211_G	0.616	0.96
363_A	368_S	0.614	0.96
257_C	261_N	0.614	0.96
300_L	304_A	0.611	0.96
271_V	275_L	0.608	0.96
254_G	264_C	0.608	0.96
102_R	106_S	0.606	0.96
360_R	370_H	0.604	0.96
217_Q	339_L	0.603	0.96
63_L	77_G	0.602	0.96
131_H	135_F	0.602	0.96
251_D	324_R	0.601	0.96
295_L	299_S	0.600	0.96
341_G	376_T	0.599	0.96
254_G	257_C	0.599	0.96
250_V	321_H	0.598	0.96
91_R	194_H	0.598	0.96
249_Q	324_R	0.597	0.96
238_G	335_P	0.597	0.96
23_R	26_D	0.596	0.96
268_I	277_L	0.596	0.96
245_I	265_L	0.596	0.96
35_D	66_K	0.596	0.96
133_D	136_F	0.596	0.96
94_R	222_H	0.594	0.95
327_A	331_N	0.593	0.95
93_S	222_H	0.588	0.95
116_L	124_L	0.588	0.95
51_V	55_L	0.586	0.95
253_Y	320_A	0.585	0.95
96_E	271_V	0.582	0.95
121_D	181_A	0.581	0.95
215_V	337_K	0.581	0.95
53_E	56_E	0.580	0.95
89_S	388_A	0.579	0.95
297_V	300_L	0.579	0.95
224_V	318_V	0.579	0.95
199_W	219_V	0.578	0.95
143_L	188_V	0.577	0.95
184_Q	187_G	0.577	0.95
252_P	320_A	0.577	0.95
191_Y	390_V	0.577	0.95
33_R	44_P	0.575	0.95
297_V	301_C	0.574	0.95
272_D	276_E	0.573	0.95
130_S	133_D	0.573	0.95
59_L	104_L	0.572	0.94
248_T	329_M	0.571	0.94
357_D	360_R	0.571	0.94
97_I	124_L	0.569	0.94
301_C	347_A	0.568	0.94
250_V	268_I	0.565	0.94
327_A	358_S	0.565	0.94
40_A	47_I	0.563	0.94
53_E	57_A	0.563	0.94
154_P	169_F	0.563	0.94
261_N	267_T	0.561	0.94
91_R	152_T	0.559	0.94
374_E	377_Q	0.559	0.94
315_I	319_G	0.556	0.94
92_I	151_I	0.554	0.93
148_S	191_Y	0.554	0.93
309_L	312_K	0.553	0.93
314_I	318_V	0.552	0.93
47_I	51_V	0.552	0.93
326_L	355_I	0.550	0.93
275_L	279_Q	0.548	0.93
251_D	321_H	0.548	0.93
218_V	226_A	0.548	0.93
248_T	265_L	0.547	0.93
378_F	385_A	0.546	0.93
254_G	262_H	0.546	0.93
140_Q	143_L	0.546	0.93
349_D	352_F	0.545	0.93
82_T	103_D	0.544	0.93
129_I	181_A	0.544	0.93
91_R	98_F	0.544	0.93
269_A	321_H	0.543	0.93
159_T	236_H	0.543	0.93
292_G	295_L	0.541	0.93
216_I	335_P	0.540	0.93
92_I	128_I	0.539	0.93
166_R	174_K	0.538	0.92
360_R	368_S	0.537	0.92
348_A	354_V	0.537	0.92
263_G	267_T	0.536	0.92
340_I	375_S	0.534	0.92
267_T	276_E	0.534	0.92
97_I	128_I	0.533	0.92
201_M	390_V	0.533	0.92
326_L	340_I	0.533	0.92
249_Q	254_G	0.533	0.92
201_M	204_A	0.531	0.92
169_F	258_Y	0.530	0.92
331_N	363_A	0.528	0.92
81_E	85_W	0.528	0.92
141_K	144_E	0.527	0.92
279_Q	283_N	0.525	0.92
226_A	245_I	0.524	0.91
24_L	27_Q	0.524	0.91
22_Y	59_L	0.523	0.91
204_A	214_D	0.522	0.91
336_Q	372_S	0.522	0.91
312_K	350_I	0.519	0.91
93_S	96_E	0.518	0.91
84_A	145_R	0.517	0.91
320_A	361_Q	0.514	0.91
153_L	178_L	0.514	0.91
162_G	183_E	0.514	0.91
327_A	362_Q	0.514	0.91
111_E	384_M	0.514	0.91
381_Q	384_M	0.512	0.91
85_W	145_R	0.511	0.90
179_G	190_V	0.511	0.90
334_N	363_A	0.511	0.90
278_A	283_N	0.509	0.90
147_T	391_K	0.508	0.90
150_A	191_Y	0.508	0.90
237_A	240_S	0.506	0.90
298_D	346_K	0.505	0.90
49_K	53_E	0.505	0.90
82_T	85_W	0.503	0.90
61_Q	83_E	0.503	0.90
273_S	276_E	0.503	0.90
341_G	345_S	0.503	0.90
326_L	329_M	0.502	0.90
49_K	52_R	0.502	0.90
91_R	343_P	0.502	0.90
271_V	343_P	0.501	0.90
204_A	213_R	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1z05A	2	0.968	100	0.177	Contact Map
1z6rA	3	0.9384	100	0.178	Contact Map
2hoeA	2	0.8695	100	0.25	Contact Map
4ijaA	2	0.9064	100	0.283	Contact Map
3o8mA	1	0.9138	100	0.382	Contact Map
2ap1A	2	0.7266	100	0.4	Contact Map
1bdgA	1	0.8695	100	0.404	Contact Map
4db3A	2	0.7414	100	0.405	Contact Map
2yhwA	2	0.7438	100	0.408	Contact Map
3f9mA	1	0.8744	100	0.416	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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