AMO - ECOLI - GREMLIN Contacts

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AMO - Primary amine oxidase

UniProt:	P46883	Sequences: MGSPSLYSARKTTLALAVALSFAWQAPVFAHGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVPVVMKDNKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLPPDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVLLDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKENRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTLGALKKDK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13140
Length:	757 (615)
Sequences:	1283 (779)
Seq/√Len:	31.4

ECOLI - AMO
SULSO - Q97XM1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
622_N	706_N	6.279	1.00
393_G	680_P	6.006	1.00
601_G	705_D	5.909	1.00
166_V	388_Y	5.586	1.00
353_I	459_V	5.017	1.00
439_L	459_V	4.828	1.00
619_S	632_S	4.424	1.00
487_V	504_F	4.115	1.00
375_V	504_F	4.009	1.00
672_R	707_T	4.007	1.00
609_K	666_K	3.924	1.00
353_I	439_L	3.766	1.00
572_S	599_N	3.733	1.00
348_I	353_I	3.698	1.00
360_F	487_V	3.655	1.00
445_D	449_V	3.607	1.00
671_T	712_W	3.602	1.00
167_W	388_Y	3.568	1.00
194_E	684_Y	3.555	1.00
579_V	596_N	3.417	1.00
354_H	359_D	3.394	1.00
387_M	564_L	3.303	1.00
570_N	707_T	3.297	1.00
353_I	360_F	3.163	1.00
348_I	439_L	3.098	1.00
602_N	704_L	3.016	1.00
572_S	706_N	2.937	1.00
385_K	565_D	2.820	1.00
163_K	708_D	2.808	1.00
179_P	198_D	2.792	1.00
352_M	359_D	2.674	1.00
137_A	182_A	2.663	1.00
459_V	485_L	2.658	1.00
621_P	705_D	2.631	1.00
573_L	709_A	2.586	1.00
620_N	631_V	2.584	1.00
332_A	356_R	2.568	1.00
441_E	456_A	2.511	1.00
723_A	742_N	2.460	0.99
184_V	197_V	2.420	0.99
575_A	608_Q	2.414	0.99
600_I	704_L	2.392	0.99
572_S	619_S	2.378	0.99
601_G	605_D	2.343	0.99
372_I	504_F	2.329	0.99
520_E	551_G	2.326	0.99
348_I	437_V	2.297	0.99
221_D	271_R	2.283	0.99
135_K	450_P	2.270	0.99
167_W	569_E	2.248	0.99
159_L	181_K	2.240	0.99
704_L	709_A	2.238	0.99
138_V	156_I	2.225	0.99
387_M	390_G	2.222	0.99
349_T	354_H	2.218	0.99
138_V	142_K	2.216	0.99
432_A	458_A	2.201	0.99
141_V	184_V	2.166	0.99
621_P	706_N	2.153	0.98
624_E	630_P	2.151	0.98
162_D	675_P	2.142	0.98
635_I	711_V	2.131	0.98
488_R	501_D	2.130	0.98
181_K	205_L	2.117	0.98
237_A	240_K	2.096	0.98
672_R	702_E	2.087	0.98
372_I	375_V	2.065	0.98
360_F	504_F	2.043	0.98
356_R	377_Y	2.042	0.98
129_L	182_A	2.034	0.98
167_W	565_D	2.028	0.98
574_V	599_N	2.019	0.98
578_P	720_V	1.998	0.97
572_S	705_D	1.957	0.97
600_I	606_A	1.956	0.97
573_L	670_V	1.953	0.97
559_N	680_P	1.953	0.97
348_I	459_V	1.933	0.97
126_L	166_V	1.920	0.97
386_V	566_V	1.876	0.96
232_S	305_I	1.867	0.96
136_Q	202_N	1.865	0.96
602_N	701_N	1.864	0.96
604_Q	701_N	1.843	0.96
482_R	505_H	1.830	0.96
425_P	453_I	1.829	0.96
603_E	702_E	1.824	0.96
565_D	569_E	1.820	0.96
131_A	442_T	1.812	0.95
270_A	299_D	1.811	0.95
181_K	196_V	1.797	0.95
467_E	752_A	1.783	0.95
357_N	378_N	1.783	0.95
674_H	702_E	1.772	0.95
442_T	452_E	1.761	0.95
607_A	666_K	1.756	0.95
542_G	550_V	1.744	0.94
623_K	631_V	1.743	0.94
372_I	487_V	1.742	0.94
520_E	545_I	1.730	0.94
674_H	677_E	1.719	0.94
125_P	166_V	1.698	0.93
182_A	199_L	1.683	0.93
618_L	709_A	1.674	0.93
390_G	562_L	1.661	0.93
626_R	745_D	1.660	0.93
234_E	237_A	1.658	0.93
284_G	322_P	1.652	0.93
183_D	684_Y	1.651	0.93
484_E	505_H	1.645	0.92
335_P	342_E	1.643	0.92
198_D	201_N	1.640	0.92
635_I	668_L	1.638	0.92
575_A	598_Y	1.635	0.92
560_F	736_T	1.613	0.92
270_A	304_K	1.612	0.92
336_M	339_I	1.609	0.91
375_V	387_M	1.608	0.91
227_N	231_N	1.607	0.91
127_N	350_G	1.605	0.91
179_P	200_Q	1.604	0.91
560_F	715_T	1.591	0.91
356_R	506_E	1.570	0.90
453_I	456_A	1.553	0.90
464_A	733_W	1.547	0.90
357_N	377_Y	1.545	0.90
384_R	567_D	1.542	0.90
583_N	652_A	1.538	0.90
163_K	388_Y	1.536	0.89
235_F	277_S	1.509	0.89
128_A	351_D	1.509	0.89
505_H	511_G	1.504	0.88
352_M	361_H	1.492	0.88
273_L	300_L	1.491	0.88
462_R	484_E	1.490	0.88
191_H	209_P	1.489	0.88
559_N	714_T	1.488	0.88
574_V	619_S	1.478	0.88
562_L	713_M	1.471	0.87
607_A	698_S	1.466	0.87
194_E	683_K	1.465	0.87
466_P	479_S	1.465	0.87
408_F	497_D	1.438	0.86
165_A	179_P	1.438	0.86
163_K	565_D	1.433	0.86
618_L	711_V	1.424	0.86
484_E	503_I	1.424	0.86
193_I	207_W	1.423	0.85
361_H	373_S	1.422	0.85
129_L	133_E	1.411	0.85
581_K	594_Q	1.411	0.85
137_A	184_V	1.410	0.85
392_L	512_I	1.410	0.85
635_I	713_M	1.393	0.84
347_T	354_H	1.389	0.84
677_E	700_D	1.382	0.84
618_L	632_S	1.381	0.84
356_R	751_G	1.380	0.84
620_N	706_N	1.373	0.83
365_N	371_M	1.369	0.83
440_N	452_E	1.357	0.83
359_D	376_T	1.356	0.83
336_M	345_N	1.353	0.82
135_K	449_V	1.353	0.82
274_K	278_Y	1.344	0.82
340_E	346_Y	1.337	0.82
638_Y	713_M	1.334	0.81
400_G	553_T	1.334	0.81
388_Y	673_Y	1.331	0.81
225_V	300_L	1.329	0.81
635_I	738_L	1.324	0.81
195_A	207_W	1.321	0.81
603_E	677_E	1.315	0.81
576_M	595_V	1.311	0.80
228_I	302_Q	1.310	0.80
466_P	490_I	1.307	0.80
523_K	552_T	1.294	0.79
468_Y	478_V	1.293	0.79
255_L	411_Y	1.290	0.79
330_A	751_G	1.288	0.79
677_E	710_V	1.288	0.79
703_S	707_T	1.284	0.79
506_E	752_A	1.281	0.79
570_N	622_N	1.265	0.78
159_L	196_V	1.259	0.78
256_T	417_Y	1.251	0.77
336_M	506_E	1.245	0.77
387_M	562_L	1.238	0.76
162_D	165_A	1.218	0.75
333_V	356_R	1.217	0.75
141_V	153_F	1.213	0.75
233_E	236_A	1.212	0.75
677_E	692_T	1.205	0.74
426_I	432_A	1.202	0.74
512_I	736_T	1.201	0.74
713_M	736_T	1.200	0.74
277_S	291_I	1.197	0.74
329_V	754_K	1.196	0.74
346_Y	437_V	1.193	0.74
672_R	704_L	1.192	0.74
427_A	454_P	1.188	0.73
490_I	497_D	1.186	0.73
409_K	521_A	1.185	0.73
632_S	709_A	1.183	0.73
349_T	352_M	1.178	0.73
196_V	510_I	1.169	0.72
717_T	720_V	1.169	0.72
601_G	706_N	1.164	0.72
272_L	306_V	1.157	0.71
233_E	237_A	1.156	0.71
443_I	451_M	1.156	0.71
141_V	195_A	1.152	0.71
545_I	549_I	1.145	0.70
562_L	738_L	1.144	0.70
674_H	700_D	1.139	0.70
297_V	309_E	1.137	0.70
396_I	661_L	1.135	0.70
167_W	385_K	1.134	0.70
261_D	264_D	1.126	0.69
388_Y	565_D	1.122	0.69
587_G	590_T	1.115	0.68
182_A	197_V	1.106	0.68
319_T	626_R	1.103	0.67
252_T	275_V	1.101	0.67
433_P	436_A	1.099	0.67
182_A	742_N	1.098	0.67
436_A	460_F	1.098	0.67
604_Q	607_A	1.098	0.67
523_K	550_V	1.098	0.67
543_T	551_G	1.097	0.67
220_D	446_Y	1.095	0.67
334_K	342_E	1.090	0.67
460_F	488_R	1.089	0.66
347_T	427_A	1.088	0.66
165_A	181_K	1.087	0.66
451_M	632_S	1.085	0.66
240_K	245_T	1.085	0.66
360_F	672_R	1.080	0.66
649_A	664_M	1.079	0.66
164_E	168_A	1.078	0.66
572_S	621_P	1.076	0.66
239_V	250_V	1.075	0.65
433_P	460_F	1.075	0.65
196_V	205_L	1.071	0.65
237_A	241_K	1.070	0.65
593_M	718_T	1.069	0.65
441_E	457_I	1.067	0.65
168_A	172_E	1.055	0.64
602_N	605_D	1.049	0.64
605_D	701_N	1.048	0.63
582_P	594_Q	1.047	0.63
463_Y	481_E	1.044	0.63
516_A	717_T	1.044	0.63
411_Y	497_D	1.044	0.63
391_S	561_R	1.039	0.63
442_T	450_P	1.039	0.63
583_N	654_D	1.035	0.62
577_D	618_L	1.032	0.62
439_L	485_L	1.031	0.62
568_G	571_N	1.027	0.62
604_Q	698_S	1.022	0.61
609_K	612_P	1.018	0.61
603_E	701_N	1.016	0.61
340_E	344_K	1.012	0.61
440_N	456_A	1.007	0.60
224_S	303_K	1.005	0.60
613_G	704_L	0.999	0.60
140_I	182_A	0.998	0.60
666_K	699_K	0.995	0.59
599_N	705_D	0.994	0.59
438_L	458_A	0.993	0.59
412_L	663_F	0.991	0.59
206_S	566_V	0.987	0.59
333_V	345_N	0.984	0.59
183_D	194_E	0.982	0.58
129_L	158_L	0.980	0.58
332_A	357_N	0.979	0.58
253_T	287_W	0.979	0.58
237_A	601_G	0.977	0.58
468_Y	747_T	0.973	0.58
375_V	390_G	0.972	0.58
719_H	725_E	0.972	0.58
298_V	305_I	0.970	0.57
205_L	268_Q	0.967	0.57
428_R	436_A	0.966	0.57
632_S	742_N	0.963	0.57
459_V	464_A	0.960	0.57
197_V	705_D	0.959	0.57
225_V	273_L	0.958	0.56
517_T	653_P	0.957	0.56
553_T	594_Q	0.956	0.56
229_I	298_V	0.956	0.56
430_K	434_S	0.953	0.56
159_L	353_I	0.945	0.55
672_R	703_S	0.944	0.55
386_V	751_G	0.944	0.55
730_P	743_F	0.941	0.55
718_T	732_E	0.940	0.55
606_A	709_A	0.938	0.55
141_V	156_I	0.934	0.55
126_L	336_M	0.932	0.54
163_K	167_W	0.925	0.54
245_T	493_V	0.922	0.54
193_I	209_P	0.921	0.53
572_S	620_N	0.920	0.53
305_I	618_L	0.917	0.53
139_E	143_A	0.917	0.53
165_A	177_D	0.915	0.53
522_V	726_W	0.913	0.53
601_G	621_P	0.909	0.52
511_G	737_L	0.908	0.52
261_D	690_H	0.903	0.52
252_T	277_S	0.900	0.52
423_T	489_W	0.898	0.52
226_Q	362_L	0.898	0.52
338_I	545_I	0.897	0.52
450_P	750_L	0.896	0.51
322_P	326_R	0.894	0.51
123_P	130_T	0.894	0.51
169_F	177_D	0.890	0.51
289_H	316_V	0.890	0.51
581_K	592_T	0.889	0.51
662_S	691_D	0.889	0.51
688_S	692_T	0.887	0.51
608_Q	611_D	0.887	0.51
575_A	616_R	0.886	0.51
464_A	484_E	0.885	0.51
414_S	419_M	0.884	0.50
187_L	301_E	0.883	0.50
620_N	632_S	0.881	0.50
549_I	726_W	0.879	0.50
197_V	585_A	0.876	0.50
321_R	325_G	0.875	0.50
537_D	581_K	0.875	0.50
165_A	178_Q	0.873	0.50
407_Y	589_R	0.872	0.49
577_D	598_Y	0.872	0.49
460_F	501_D	0.868	0.49
576_M	617_L	0.868	0.49
236_A	247_A	0.868	0.49
363_S	371_M	0.868	0.49
353_I	362_L	0.867	0.49
658_Y	665_D	0.867	0.49
578_P	593_M	0.866	0.49
452_E	699_K	0.865	0.49
323_F	493_V	0.863	0.49
455_R	568_G	0.862	0.49
232_S	235_F	0.862	0.49
696_Q	699_K	0.859	0.48
653_P	658_Y	0.856	0.48
717_T	732_E	0.854	0.48
604_Q	673_Y	0.854	0.48
467_E	506_E	0.854	0.48
432_A	438_L	0.853	0.48
566_V	668_L	0.852	0.48
163_K	571_N	0.850	0.48
171_L	178_Q	0.848	0.48
271_R	371_M	0.847	0.47
305_I	701_N	0.846	0.47
579_V	594_Q	0.845	0.47
358_W	712_W	0.844	0.47
140_I	199_L	0.844	0.47
553_T	721_A	0.844	0.47
411_Y	634_Q	0.842	0.47
255_L	474_G	0.841	0.47
253_T	474_G	0.841	0.47
425_P	456_A	0.839	0.47
401_D	729_M	0.837	0.47
499_I	515_G	0.836	0.47
662_S	695_G	0.836	0.47
122_R	596_N	0.835	0.46
516_A	520_E	0.835	0.46
384_R	660_R	0.832	0.46
185_I	215_G	0.832	0.46
455_R	752_A	0.829	0.46
562_L	711_V	0.828	0.46
600_I	605_D	0.824	0.46
691_D	695_G	0.823	0.46
449_V	699_K	0.823	0.46
443_I	453_I	0.820	0.45
196_V	676_G	0.820	0.45
140_I	197_V	0.819	0.45
242_R	310_E	0.819	0.45
284_G	488_R	0.818	0.45
231_N	236_A	0.816	0.45
205_L	372_I	0.814	0.45
525_V	539_T	0.814	0.45
500_F	668_L	0.814	0.45
329_V	332_A	0.813	0.45
242_R	291_I	0.811	0.45
140_I	198_D	0.808	0.44
692_T	696_Q	0.808	0.44
227_N	240_K	0.808	0.44
236_A	240_K	0.807	0.44
154_T	218_L	0.807	0.44
593_M	657_I	0.807	0.44
163_K	709_A	0.806	0.44
364_M	423_T	0.804	0.44
566_V	709_A	0.804	0.44
459_V	504_F	0.803	0.44
620_N	623_K	0.803	0.44
388_Y	569_E	0.802	0.44
488_R	499_I	0.801	0.44
520_E	549_I	0.801	0.44
565_D	708_D	0.801	0.44
501_D	513_D	0.798	0.44
306_V	540_R	0.798	0.44
462_R	488_R	0.797	0.43
468_Y	480_T	0.797	0.43
567_D	631_V	0.796	0.43
486_V	588_P	0.795	0.43
165_A	168_A	0.794	0.43
358_W	671_T	0.794	0.43
132_D	135_K	0.792	0.43
130_T	133_E	0.789	0.43
606_A	701_N	0.789	0.43
331_P	349_T	0.786	0.43
321_R	324_D	0.785	0.42
241_K	493_V	0.784	0.42
424_S	471_Q	0.784	0.42
272_L	297_V	0.784	0.42
428_R	455_R	0.784	0.42
182_A	452_E	0.784	0.42
336_M	685_P	0.783	0.42
238_A	241_K	0.781	0.42
334_K	345_N	0.779	0.42
157_S	365_N	0.778	0.42
238_A	242_R	0.777	0.42
694_L	698_S	0.777	0.42
163_K	677_E	0.777	0.42
344_K	435_N	0.777	0.42
339_I	504_F	0.777	0.42
321_R	549_I	0.774	0.42
630_P	653_P	0.773	0.42
637_P	713_M	0.771	0.41
747_T	752_A	0.771	0.41
272_L	487_V	0.770	0.41
662_S	665_D	0.768	0.41
648_G	718_T	0.768	0.41
728_I	747_T	0.767	0.41
126_L	374_T	0.767	0.41
375_V	386_V	0.766	0.41
169_F	489_W	0.763	0.41
159_L	183_D	0.763	0.41
124_H	127_N	0.762	0.41
500_F	637_P	0.761	0.41
582_P	590_T	0.759	0.40
170_A	173_N	0.758	0.40
396_I	472_E	0.758	0.40
219_L	491_S	0.758	0.40
374_T	675_P	0.758	0.40
436_A	469_K	0.757	0.40
566_V	622_N	0.757	0.40
229_I	236_A	0.755	0.40
384_R	631_V	0.755	0.40
224_S	227_N	0.754	0.40
396_I	410_A	0.754	0.40
220_D	224_S	0.753	0.40
144_S	204_L	0.752	0.40
229_I	275_V	0.752	0.40
357_N	751_G	0.751	0.40
422_L	493_V	0.748	0.40
434_S	460_F	0.747	0.39
241_K	310_E	0.746	0.39
621_P	632_S	0.746	0.39
545_I	579_V	0.745	0.39
434_S	438_L	0.745	0.39
199_L	207_W	0.743	0.39
166_V	374_T	0.742	0.39
436_A	488_R	0.742	0.39
573_L	711_V	0.742	0.39
433_P	488_R	0.742	0.39
128_A	363_S	0.739	0.39
424_S	469_K	0.738	0.39
132_D	400_G	0.738	0.39
464_A	482_R	0.737	0.39
210_I	213_A	0.736	0.39
199_L	205_L	0.736	0.39
233_E	305_I	0.736	0.39
490_I	499_I	0.735	0.39
226_Q	474_G	0.729	0.38
166_V	306_V	0.729	0.38
345_N	483_R	0.729	0.38
232_S	650_Q	0.726	0.38
559_N	712_W	0.726	0.38
323_F	559_N	0.726	0.38
431_D	469_K	0.724	0.38
575_A	600_I	0.724	0.38
124_H	361_H	0.724	0.38
141_V	684_Y	0.724	0.38
157_S	366_S	0.722	0.38
489_W	500_F	0.722	0.38
231_N	304_K	0.721	0.37
559_N	734_V	0.717	0.37
390_G	510_I	0.716	0.37
169_F	371_M	0.716	0.37
392_L	560_F	0.715	0.37
651_F	718_T	0.715	0.37
469_K	555_Q	0.714	0.37
543_T	553_T	0.713	0.37
169_F	351_D	0.712	0.37
570_N	601_G	0.711	0.37
390_G	502_W	0.710	0.37
601_G	709_A	0.707	0.36
353_I	601_G	0.705	0.36
430_K	460_F	0.705	0.36
197_V	452_E	0.703	0.36
171_L	347_T	0.702	0.36
605_D	608_Q	0.702	0.36
570_N	621_P	0.701	0.36
336_M	504_F	0.699	0.36
651_F	664_M	0.697	0.36
605_D	704_L	0.696	0.36
194_E	673_Y	0.695	0.36
672_R	698_S	0.694	0.35
455_R	472_E	0.694	0.35
195_A	204_L	0.694	0.35
139_E	699_K	0.692	0.35
670_V	704_L	0.691	0.35
342_E	357_N	0.690	0.35
254_P	438_L	0.690	0.35
571_N	709_A	0.690	0.35
482_R	506_E	0.689	0.35
169_F	172_E	0.688	0.35
363_S	618_L	0.687	0.35
663_F	681_E	0.686	0.35
404_I	407_Y	0.685	0.35
599_N	619_S	0.684	0.35
346_Y	573_L	0.684	0.35
156_I	598_Y	0.683	0.35
426_I	458_A	0.683	0.35
424_S	428_R	0.683	0.35
348_I	505_H	0.681	0.34
494_G	593_M	0.681	0.34
185_I	194_E	0.681	0.34
225_V	252_T	0.681	0.34
423_T	456_A	0.676	0.34
401_D	552_T	0.674	0.34
258_G	448_G	0.674	0.34
336_M	356_R	0.674	0.34
581_K	652_A	0.673	0.34
430_K	436_A	0.671	0.34
314_V	321_R	0.670	0.34
722_R	730_P	0.670	0.34
228_I	304_K	0.670	0.34
502_W	713_M	0.669	0.34
141_V	263_K	0.668	0.34
411_Y	494_G	0.668	0.34
156_I	444_A	0.666	0.33
291_I	520_E	0.664	0.33
578_P	585_A	0.664	0.33
688_S	691_D	0.664	0.33
738_L	744_F	0.664	0.33
457_I	487_V	0.663	0.33
541_Y	720_V	0.663	0.33
577_D	670_V	0.662	0.33
323_F	422_L	0.661	0.33
244_I	250_V	0.661	0.33
122_R	171_L	0.661	0.33
294_L	596_N	0.660	0.33
571_N	708_D	0.659	0.33
617_L	632_S	0.658	0.33
328_R	331_P	0.658	0.33
166_V	373_S	0.658	0.33
679_F	743_F	0.658	0.33
214_H	723_A	0.657	0.33
743_F	747_T	0.657	0.33
712_W	740_P	0.656	0.33
298_V	459_V	0.656	0.33
389_E	434_S	0.655	0.33
222_F	254_P	0.655	0.33
570_N	704_L	0.654	0.33
304_K	349_T	0.653	0.32
233_E	347_T	0.652	0.32
158_L	180_R	0.652	0.32
169_F	734_V	0.652	0.32
411_Y	516_A	0.652	0.32
507_N	749_T	0.651	0.32
136_Q	139_E	0.650	0.32
144_S	375_V	0.649	0.32
202_N	570_N	0.648	0.32
628_G	679_F	0.648	0.32
240_K	244_I	0.646	0.32
566_V	711_V	0.645	0.32
406_W	521_A	0.643	0.32
397_V	553_T	0.642	0.32
439_L	504_F	0.642	0.32
340_E	343_G	0.641	0.32
726_W	729_M	0.640	0.32
146_D	149_P	0.639	0.31
206_S	439_L	0.639	0.31
322_P	325_G	0.639	0.31
140_I	205_L	0.639	0.31
351_D	407_Y	0.638	0.31
495_N	498_Y	0.638	0.31
175_P	203_K	0.638	0.31
234_E	308_I	0.638	0.31
209_P	212_D	0.636	0.31
740_P	751_G	0.636	0.31
345_N	430_K	0.635	0.31
182_A	482_R	0.635	0.31
712_W	738_L	0.633	0.31
546_D	681_E	0.633	0.31
138_V	445_D	0.633	0.31
692_T	695_G	0.633	0.31
354_H	632_S	0.631	0.31
719_H	727_P	0.631	0.31
298_V	541_Y	0.630	0.31
334_K	338_I	0.629	0.31
557_I	649_A	0.629	0.31
573_L	635_I	0.629	0.31
306_V	627_M	0.628	0.31
629_N	632_S	0.628	0.31
332_A	377_Y	0.627	0.31
332_A	752_A	0.627	0.31
455_R	571_N	0.626	0.31
499_I	517_T	0.626	0.31
417_Y	422_L	0.625	0.31
136_Q	140_I	0.625	0.31
156_I	639_A	0.625	0.31
653_P	698_S	0.624	0.30
289_H	680_P	0.624	0.30
565_D	677_E	0.623	0.30
234_E	307_K	0.623	0.30
170_A	178_Q	0.621	0.30
226_Q	473_M	0.621	0.30
566_V	659_H	0.621	0.30
351_D	612_P	0.620	0.30
217_V	300_L	0.619	0.30
459_V	666_K	0.619	0.30
428_R	469_K	0.619	0.30
601_G	632_S	0.619	0.30
287_W	323_F	0.618	0.30
142_K	668_L	0.618	0.30
190_K	206_S	0.618	0.30
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574_V	597_Q	0.617	0.30
577_D	596_N	0.617	0.30
146_D	677_E	0.616	0.30
147_F	151_T	0.615	0.30
743_F	748_P	0.615	0.30
497_D	734_V	0.614	0.30
360_F	599_N	0.613	0.30
258_G	660_R	0.613	0.30
417_Y	494_G	0.612	0.30
666_K	669_W	0.612	0.30
125_P	448_G	0.612	0.30
684_Y	749_T	0.612	0.30
285_N	336_M	0.611	0.30
413_D	461_E	0.611	0.30
555_Q	718_T	0.611	0.30
362_L	679_F	0.611	0.30
418_G	438_L	0.610	0.29
228_I	308_I	0.610	0.29
170_A	586_G	0.610	0.29
510_I	560_F	0.610	0.29
209_P	696_Q	0.610	0.29
450_P	684_Y	0.609	0.29
467_E	709_A	0.609	0.29
232_S	711_V	0.609	0.29
171_L	174_K	0.609	0.29
425_P	440_N	0.608	0.29
598_Y	605_D	0.608	0.29
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557_I	714_T	0.606	0.29
436_A	515_G	0.606	0.29
375_V	564_L	0.606	0.29
430_K	463_Y	0.606	0.29
374_T	388_Y	0.606	0.29
127_N	362_L	0.605	0.29
142_K	353_I	0.605	0.29
192_I	680_P	0.603	0.29
577_D	614_T	0.602	0.29
626_R	704_L	0.602	0.29
578_P	718_T	0.600	0.29
494_G	628_G	0.598	0.29
217_V	273_L	0.598	0.29
291_I	631_V	0.598	0.29
331_P	466_P	0.596	0.29
438_L	460_F	0.595	0.28
178_Q	570_N	0.595	0.28
502_W	562_L	0.593	0.28
134_I	350_G	0.593	0.28
178_Q	720_V	0.592	0.28
661_L	721_A	0.592	0.28
622_N	707_T	0.591	0.28
716_G	719_H	0.591	0.28
416_D	685_P	0.591	0.28
641_G	718_T	0.590	0.28
630_P	750_L	0.590	0.28
125_P	158_L	0.590	0.28
362_L	439_L	0.590	0.28
525_V	544_L	0.590	0.28
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169_F	178_Q	0.589	0.28
153_F	158_L	0.588	0.28
433_P	501_D	0.587	0.28
387_M	566_V	0.587	0.28
468_Y	728_I	0.587	0.28
557_I	713_M	0.587	0.28
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616_R	668_L	0.581	0.28
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390_G	755_K	0.581	0.28
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148_K	184_V	0.580	0.27
460_F	463_Y	0.580	0.27
158_L	365_N	0.580	0.27
500_F	558_Y	0.580	0.27
527_A	548_N	0.579	0.27
360_F	482_R	0.578	0.27
590_T	655_E	0.578	0.27
388_Y	628_G	0.578	0.27
346_Y	372_I	0.577	0.27
676_G	702_E	0.577	0.27
451_M	750_L	0.577	0.27
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607_A	704_L	0.577	0.27
508_G	600_I	0.576	0.27
547_H	559_N	0.576	0.27
130_T	709_A	0.575	0.27
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447_T	504_F	0.573	0.27
595_V	672_R	0.573	0.27
253_T	418_G	0.573	0.27
377_Y	400_G	0.572	0.27
602_N	622_N	0.571	0.27
507_N	616_R	0.571	0.27
162_D	673_Y	0.570	0.27
192_I	215_G	0.570	0.27
294_L	411_Y	0.570	0.27
491_S	500_F	0.570	0.27
620_N	704_L	0.570	0.27
419_M	560_F	0.569	0.27
360_F	386_V	0.569	0.27
196_V	206_S	0.569	0.27
450_P	594_Q	0.568	0.27
196_V	493_V	0.568	0.27
175_P	504_F	0.567	0.27
126_L	367_R	0.567	0.27
156_I	572_S	0.567	0.27
287_W	514_A	0.565	0.27
166_V	673_Y	0.565	0.27
166_V	171_L	0.565	0.27
354_H	378_N	0.564	0.26
162_D	199_L	0.564	0.26
393_G	559_N	0.563	0.26
200_Q	280_D	0.563	0.26
198_D	205_L	0.562	0.26
610_F	713_M	0.562	0.26
520_E	542_G	0.561	0.26
487_V	623_K	0.561	0.26
516_A	662_S	0.560	0.26
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127_N	361_H	0.559	0.26
364_M	560_F	0.558	0.26
459_V	623_K	0.558	0.26
549_I	688_S	0.558	0.26
627_M	745_D	0.557	0.26
541_Y	553_T	0.556	0.26
620_N	624_E	0.556	0.26
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483_R	555_Q	0.556	0.26
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125_P	367_R	0.555	0.26
302_Q	307_K	0.554	0.26
624_E	631_V	0.554	0.26
338_I	499_I	0.554	0.26
356_R	561_R	0.553	0.26
476_P	494_G	0.553	0.26
220_D	750_L	0.552	0.26
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476_P	631_V	0.551	0.26
486_V	514_A	0.551	0.26
338_I	506_E	0.551	0.26
522_V	543_T	0.551	0.26
603_E	700_D	0.551	0.26
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460_F	614_T	0.549	0.26
542_G	718_T	0.549	0.26
673_Y	678_R	0.549	0.26
159_L	676_G	0.548	0.25
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140_I	703_S	0.547	0.25
287_W	687_R	0.547	0.25
724_E	727_P	0.547	0.25
203_K	227_N	0.546	0.25
395_M	469_K	0.546	0.25
417_Y	521_A	0.545	0.25
144_S	179_P	0.545	0.25
316_V	459_V	0.544	0.25
570_N	706_N	0.544	0.25
577_D	630_P	0.544	0.25
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545_I	604_Q	0.542	0.25
297_V	336_M	0.542	0.25
347_T	711_V	0.542	0.25
411_Y	474_G	0.542	0.25
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566_V	599_N	0.541	0.25
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141_V	621_P	0.539	0.25
564_L	736_T	0.539	0.25
150_N	374_T	0.538	0.25
504_F	627_M	0.538	0.25
343_G	551_G	0.538	0.25
308_I	353_I	0.538	0.25
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587_G	655_E	0.535	0.25
300_L	494_G	0.535	0.25
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665_D	668_L	0.534	0.25
708_D	725_E	0.534	0.25
279_L	318_M	0.534	0.25
360_F	459_V	0.533	0.25
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571_N	620_N	0.532	0.24
389_E	460_F	0.532	0.24
441_E	450_P	0.530	0.24
630_P	728_I	0.530	0.24
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392_L	626_R	0.530	0.24
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511_G	733_W	0.529	0.24
191_H	233_E	0.529	0.24
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323_F	634_Q	0.527	0.24
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635_I	698_S	0.524	0.24
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681_E	723_A	0.508	0.23
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358_W	751_G	0.505	0.23
251_I	516_A	0.504	0.23
260_F	291_I	0.504	0.23
153_F	156_I	0.504	0.23
600_I	623_K	0.504	0.23
463_Y	483_R	0.503	0.23
346_Y	436_A	0.503	0.23
394_G	546_D	0.503	0.23
485_L	705_D	0.502	0.23
483_R	669_W	0.502	0.23
223_A	227_N	0.501	0.23
559_N	671_T	0.501	0.23
321_R	596_N	0.501	0.23
164_E	203_K	0.500	0.23
372_I	723_A	0.500	0.23
362_L	504_F	0.500	0.23

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1spuA	2	0.9511	100	0.178	Contact Map
3sxxA	5	0.8217	100	0.243	Contact Map
1ksiA	2	0.8177	100	0.249	Contact Map
3wa2X	2	0.8018	100	0.249	Contact Map
3loyA	2	0.8032	100	0.263	Contact Map
1tu5A	2	0.7503	100	0.287	Contact Map
3hi7A	2	0.8032	100	0.295	Contact Map
3pgbA	2	0.819	100	0.304	Contact Map
1w7cA	2	0.8164	100	0.305	Contact Map
2wtpA	2	0.1149	19.3	0.989	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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