GREMLIN Database
AAEB - p-hydroxybenzoic acid efflux pump subunit AaeB
UniProt: P46481 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12822
Length: 655 (620)
Sequences: 988 (756)
Seq/√Len: 30.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
330_I333_T4.5791.00
330_I337_I4.1901.00
104_G358_F4.0281.00
333_T337_I3.9231.00
104_G362_T3.8331.00
26_F432_S3.8141.00
108_W351_R3.5721.00
71_I154_V3.3371.00
319_L330_I3.3131.00
327_N330_I3.2731.00
319_L322_R3.2611.00
327_N334_E3.2311.00
250_T257_L3.2111.00
334_E337_I3.2071.00
100_C366_I3.1791.00
18_A22_V3.1771.00
330_I334_E3.1231.00
291_L295_I3.0511.00
327_N337_I3.0251.00
102_W106_C2.9261.00
251_Q255_T2.8231.00
96_I369_T2.8081.00
592_R596_D2.7871.00
308_Y312_A2.7811.00
250_T256_Y2.7721.00
442_V446_F2.6571.00
312_A316_R2.6521.00
419_L482_F2.5781.00
326_S330_I2.5781.00
250_T253_C2.5450.99
23_L159_C2.5290.99
250_T255_T2.5260.99
316_R319_L2.5150.99
123_L126_Y2.4880.99
88_M98_V2.4800.99
119_Y123_L2.4540.99
27_V155_I2.3830.99
326_S333_T2.3500.99
316_R327_N2.3430.99
568_I574_R2.3060.99
251_Q257_L2.3020.99
310_W319_L2.2850.99
619_E622_Q2.2790.99
326_S334_E2.2760.99
436_L440_L2.2740.99
317_Y320_L2.2710.99
522_A545_Q2.2620.99
614_L619_E2.2490.99
315_T322_R2.2440.99
319_L327_N2.2160.99
154_V158_V2.1950.98
276_T294_V2.1820.98
522_A541_A2.1660.98
587_F591_M2.1570.98
614_L618_L2.1440.98
316_R330_I2.1220.98
618_L622_Q2.1050.98
319_L324_V2.1030.98
429_T439_S2.0940.98
131_I146_A2.0920.98
327_N333_T2.0770.98
308_Y316_R2.0730.98
253_C256_Y2.0730.98
129_L388_A2.0630.98
614_L621_Y2.0440.98
432_S437_C2.0240.97
284_V287_Q2.0190.97
312_A326_S2.0020.97
418_G482_F1.9950.97
316_R321_K1.9860.97
326_S337_I1.9660.97
21_I44_A1.9250.96
130_I389_V1.9210.96
147_V151_S1.9210.96
295_I299_G1.9200.96
133_I369_T1.9200.96
315_T333_T1.9190.96
13_F451_V1.9140.96
16_K60_S1.9060.96
542_L545_Q1.8800.96
350_E514_V1.8780.96
412_L490_I1.8630.96
614_L622_Q1.8540.96
541_A545_Q1.8460.95
541_A544_Q1.8460.95
307_I310_W1.8340.95
312_A315_T1.8300.95
253_C257_L1.8180.95
460_G526_A1.8170.95
102_W124_A1.8100.95
599_I603_S1.7950.95
72_I75_F1.7890.95
614_L617_E1.7800.94
312_A333_T1.7710.94
162_M166_L1.7670.94
22_V437_C1.7650.94
78_C150_C1.7630.94
14_A44_A1.7620.94
93_L370_L1.7480.94
316_R326_S1.7420.94
312_A319_L1.7370.94
309_S316_R1.7350.94
595_A599_I1.7320.94
615_L622_Q1.7270.93
19_T167_F1.7150.93
271_R275_D1.7150.93
540_P544_Q1.7060.93
368_G387_I1.6960.93
306_T309_S1.6930.93
392_S395_M1.6890.93
321_K327_N1.6880.93
320_L326_S1.6870.93
329_K333_T1.6860.93
453_K456_L1.6840.93
78_C82_L1.6740.92
316_R337_I1.6690.92
635_T638_V1.6570.92
309_S312_A1.6510.92
324_V330_I1.6360.91
321_K337_I1.6310.91
284_V288_L1.6270.91
44_A448_G1.6240.91
370_L374_W1.6140.91
615_L619_E1.6130.91
415_L486_A1.6090.91
315_T319_L1.6080.91
316_R323_G1.6000.91
312_A330_I1.5820.90
321_K324_V1.5810.90
436_L454_R1.5620.89
316_R334_E1.5580.89
320_L323_G1.5520.89
618_L621_Y1.5460.89
331_N334_E1.5460.89
309_S321_K1.5350.89
306_T310_W1.5340.89
417_L461_A1.5340.89
321_K330_I1.5330.88
291_L294_V1.5320.88
338_L342_P1.5290.88
45_I451_V1.5280.88
292_R296_A1.5260.88
599_I606_K1.5130.88
308_Y319_L1.5080.88
350_E545_Q1.4940.87
538_H544_Q1.4760.87
276_T280_T1.4690.86
70_R119_Y1.4570.86
312_A321_K1.4570.86
80_A98_V1.4490.85
334_E338_L1.4320.85
385_V392_S1.4270.85
613_Q617_E1.4250.84
180_L241_I1.4230.84
108_W358_F1.4190.84
377_W380_G1.4170.84
252_S255_T1.4150.84
372_W380_G1.4100.84
27_V159_C1.4090.84
326_S329_K1.3990.83
124_A375_T1.3980.83
321_K326_S1.3930.83
574_R580_V1.3910.83
102_W126_Y1.3900.83
45_I389_V1.3890.83
38_W152_E1.3870.83
596_D599_I1.3830.83
319_L337_I1.3820.83
420_L424_V1.3740.82
308_Y330_I1.3690.82
78_C146_A1.3660.82
321_K333_T1.3620.82
351_R358_F1.3580.81
107_T392_S1.3470.81
250_T254_E1.3380.80
313_A317_Y1.3260.80
287_Q292_R1.3250.80
535_K539_L1.3250.80
311_V315_T1.3230.80
72_I120_A1.3170.79
292_R295_I1.3150.79
309_S330_I1.3140.79
95_M157_I1.3130.79
42_T153_I1.3050.79
287_Q363_L1.3010.79
596_D602_R1.2980.78
106_C128_A1.2880.78
121_W226_M1.2850.78
314_A317_Y1.2710.77
111_S357_N1.2600.76
227_E244_L1.2570.76
535_K538_H1.2570.76
619_E623_E1.2530.76
60_S152_E1.2530.76
82_L146_A1.2520.76
99_C128_A1.2510.76
20_A43_A1.2440.75
70_R126_Y1.2390.75
538_H542_L1.2370.75
431_Q434_L1.2370.75
16_K606_K1.2320.75
252_S256_Y1.2290.74
249_I252_S1.2240.74
284_V292_R1.2220.74
135_I145_F1.2210.74
311_V314_A1.2210.74
249_I257_L1.2160.74
125_G393_L1.2140.74
16_K169_P1.2080.73
539_L543_Y1.2070.73
632_P636_E1.2060.73
571_Q574_R1.2050.73
84_I98_V1.2010.73
324_V327_N1.1970.72
65_Y223_N1.1970.72
538_H545_Q1.1940.72
119_Y126_Y1.1920.72
602_R606_K1.1910.72
278_V281_A1.1880.72
611_F620_I1.1810.71
122_G410_G1.1800.71
70_R74_T1.1780.71
266_I281_A1.1770.71
617_E621_Y1.1770.71
45_I426_I1.1710.71
313_A330_I1.1690.71
121_W152_E1.1640.70
152_E226_M1.1570.70
625_L628_W1.1520.69
74_T119_Y1.1520.69
412_L416_P1.1470.69
324_V333_T1.1470.69
24_A39_A1.1440.69
372_W377_W1.1420.69
168_S173_K1.1380.69
634_V637_P1.1370.68
535_K545_Q1.1370.68
617_E625_L1.1350.68
148_E151_S1.1340.68
120_A131_I1.1260.68
597_H618_L1.1210.67
106_C126_Y1.1150.67
101_I355_M1.1140.67
184_L210_L1.1130.67
16_K167_F1.1070.66
155_I304_P1.1050.66
313_A316_R1.1050.66
299_G302_E1.1040.66
15_V167_F1.1030.66
109_I451_V1.1020.66
380_G400_P1.0960.66
164_D172_I1.0950.65
106_C354_A1.0940.65
341_E344_V1.0940.65
70_R123_L1.0930.65
321_K334_E1.0890.65
394_A496_A1.0890.65
620_I624_K1.0890.65
578_I581_N1.0870.65
106_C124_A1.0870.65
221_R226_M1.0860.65
364_S367_L1.0860.65
319_L323_G1.0840.65
534_R537_N1.0840.65
312_A322_R1.0810.64
368_G495_L1.0790.64
598_V602_R1.0760.64
123_L393_L1.0720.64
598_V605_D1.0680.64
100_C365_C1.0670.63
339_Q343_E1.0660.63
28_G537_N1.0650.63
35_T38_W1.0620.63
377_W484_D1.0590.63
254_E257_L1.0580.63
313_A331_N1.0530.62
14_A38_W1.0510.62
598_V606_K1.0500.62
328_T333_T1.0500.62
24_A156_G1.0500.62
43_A492_G1.0490.62
622_Q625_L1.0460.62
371_F502_L1.0410.61
398_P552_K1.0380.61
549_L567_I1.0360.61
12_R16_K1.0320.61
80_A102_W1.0290.61
317_Y330_I1.0250.60
539_L545_Q1.0240.60
31_F459_M1.0220.60
251_Q256_Y1.0220.60
350_E394_A1.0200.60
317_Y324_V1.0180.60
273_F280_T1.0160.60
615_L618_L1.0150.60
38_W92_P1.0150.60
324_V328_T1.0150.60
301_R304_P1.0070.59
62_A448_G1.0070.59
96_I111_S1.0060.59
410_G447_L1.0040.59
322_R326_S1.0020.59
244_L247_T0.9970.58
615_L621_Y0.9960.58
69_L117_N0.9960.58
283_D290_R0.9940.58
345_K349_A0.9930.58
454_R457_G0.9920.58
155_I282_Q0.9900.58
315_T320_L0.9890.57
345_K350_E0.9870.57
123_L132_V0.9850.57
116_E360_R0.9850.57
126_Y393_L0.9850.57
312_A334_E0.9820.57
286_K597_H0.9820.57
590_Q612_G0.9790.57
611_F615_L0.9790.57
44_A57_E0.9770.57
540_P548_L0.9740.56
44_A152_E0.9740.56
287_Q290_R0.9740.56
544_Q548_L0.9730.56
269_T582_E0.9720.56
309_S314_A0.9680.56
299_G303_T0.9670.56
337_I340_G0.9640.56
37_R223_N0.9630.55
14_A18_A0.9630.55
267_T281_A0.9620.55
122_G393_L0.9610.55
587_F595_A0.9580.55
12_R15_V0.9580.55
251_Q254_E0.9580.55
283_D288_L0.9570.55
81_G130_I0.9530.55
368_G383_A0.9510.55
317_Y333_T0.9470.54
107_T111_S0.9450.54
57_E376_G0.9450.54
399_N505_D0.9410.54
597_H601_A0.9410.54
127_T153_I0.9390.54
47_A160_A0.9360.53
380_G484_D0.9350.53
612_G617_E0.9330.53
19_T441_A0.9310.53
267_T280_T0.9310.53
610_Y619_E0.9310.53
406_D409_Y0.9220.52
616_E620_I0.9210.52
32_Q164_D0.9210.52
16_K121_W0.9190.52
40_V226_M0.9190.52
78_C131_I0.9180.52
315_T321_K0.9160.52
535_K540_P0.9150.52
116_E427_P0.9130.51
615_L631_P0.9100.51
329_K337_I0.9100.51
540_P545_Q0.9040.51
65_Y126_Y0.9040.51
86_I90_R0.9020.51
626_R633_Q0.9010.51
42_T122_G0.9010.51
518_Q545_Q0.9000.50
109_I121_W0.9000.50
17_L164_D0.9000.50
21_I40_V0.8990.50
634_V638_V0.8980.50
287_Q295_I0.8970.50
285_H303_T0.8970.50
320_L327_N0.8970.50
423_L482_F0.8960.50
138_E141_L0.8940.50
308_Y320_L0.8890.50
144_Q348_S0.8870.49
408_I494_V0.8870.49
45_I123_L0.8870.49
437_C444_G0.8860.49
271_R279_E0.8840.49
111_S360_R0.8840.49
323_G330_I0.8820.49
417_L420_L0.8810.49
523_A527_M0.8790.49
45_I436_L0.8770.49
314_A327_N0.8730.48
35_T152_E0.8730.48
308_Y326_S0.8720.48
316_R322_R0.8710.48
421_Y425_I0.8700.48
309_S320_L0.8680.48
627_I635_T0.8670.48
632_P635_T0.8650.48
152_E169_P0.8640.48
13_F25_L0.8620.47
609_R619_E0.8620.47
187_Q195_I0.8620.47
309_S319_L0.8610.47
631_P635_T0.8610.47
319_L326_S0.8600.47
324_V337_I0.8590.47
607_R619_E0.8590.47
617_E622_Q0.8580.47
164_D538_H0.8550.47
369_T384_M0.8530.47
74_T149_R0.8520.47
112_L351_R0.8480.46
318_Q330_I0.8470.46
295_I302_E0.8460.46
101_I417_L0.8460.46
290_R294_V0.8450.46
555_G568_I0.8450.46
438_I627_I0.8450.46
482_F486_A0.8450.46
69_L144_Q0.8410.46
591_M595_A0.8410.46
63_I466_I0.8400.46
330_I336_E0.8380.45
69_L153_I0.8380.45
618_L623_E0.8360.45
20_A106_C0.8300.45
92_P136_Q0.8300.45
420_L616_E0.8290.45
316_R324_V0.8270.45
86_I151_S0.8230.44
382_G467_N0.8230.44
333_T340_G0.8220.44
146_A487_L0.8210.44
42_T139_P0.8200.44
312_A324_V0.8160.44
605_D617_E0.8130.44
57_E69_L0.8120.43
382_G385_V0.8100.43
359_W608_R0.8100.43
363_L416_P0.8060.43
598_V603_S0.8060.43
468_I486_A0.8060.43
106_C360_R0.8050.43
88_M526_A0.8050.43
310_W326_S0.8030.43
612_G615_L0.8020.43
319_L334_E0.8020.43
395_M407_F0.8000.43
360_R473_N0.8000.43
79_I582_E0.7990.42
42_T439_S0.7990.42
537_N540_P0.7990.42
593_R604_D0.7980.42
228_S231_W0.7960.42
574_R581_N0.7910.42
231_W238_L0.7910.42
78_C145_F0.7900.42
491_V613_Q0.7900.42
354_A358_F0.7890.42
308_Y315_T0.7890.42
268_D558_P0.7890.42
540_P546_L0.7880.42
66_R143_P0.7850.41
28_G75_F0.7830.41
630_A635_T0.7820.41
320_L330_I0.7820.41
132_V390_V0.7820.41
321_K342_P0.7810.41
618_L624_K0.7780.41
391_T496_A0.7760.41
126_Y153_I0.7750.41
17_L62_A0.7740.40
81_G498_T0.7740.40
625_L629_Q0.7700.40
538_H541_A0.7700.40
611_F618_L0.7670.40
591_M594_T0.7650.40
391_T468_I0.7650.40
272_E293_R0.7640.40
317_Y328_T0.7640.40
574_R578_I0.7630.40
152_E241_I0.7610.39
631_P638_V0.7600.39
27_V32_Q0.7600.39
312_A320_L0.7600.39
289_K293_R0.7600.39
114_R163_A0.7590.39
360_R500_I0.7580.39
193_L587_F0.7570.39
610_Y622_Q0.7560.39
603_S606_K0.7560.39
333_T336_E0.7560.39
306_T317_Y0.7540.39
26_F30_H0.7490.39
87_A90_R0.7480.39
404_A493_C0.7470.38
143_P147_V0.7470.38
464_S472_D0.7440.38
16_K526_A0.7440.38
83_V597_H0.7430.38
268_D289_K0.7420.38
323_G327_N0.7420.38
311_V321_K0.7420.38
625_L631_P0.7420.38
306_T342_P0.7420.38
602_R605_D0.7410.38
389_V407_F0.7410.38
33_L58_P0.7400.38
285_H289_K0.7390.38
617_E631_P0.7370.38
358_F435_L0.7360.38
348_S545_Q0.7350.38
79_I83_V0.7350.38
577_P599_I0.7350.38
272_E276_T0.7350.38
104_G444_G0.7350.38
592_R632_P0.7340.37
445_F577_P0.7340.37
83_V264_E0.7330.37
210_L393_L0.7320.37
24_A29_F0.7310.37
399_N407_F0.7300.37
310_W330_I0.7290.37
601_A605_D0.7280.37
42_T70_R0.7280.37
383_A492_G0.7270.37
545_Q548_L0.7260.37
37_R92_P0.7260.37
535_K541_A0.7250.37
265_L269_T0.7230.37
451_V457_G0.7220.37
62_A572_R0.7200.36
523_A540_P0.7190.36
163_A390_V0.7190.36
79_I329_K0.7190.36
398_P460_G0.7190.36
32_Q347_E0.7180.36
494_V497_F0.7170.36
143_P432_S0.7160.36
584_L593_R0.7150.36
367_L495_L0.7150.36
123_L153_I0.7150.36
593_R632_P0.7140.36
611_F619_E0.7130.36
315_T330_I0.7120.36
407_F460_G0.7120.36
130_I449_I0.7100.36
537_N541_A0.7090.36
112_L499_V0.7090.36
604_D608_R0.7090.36
69_L116_E0.7070.35
537_N545_Q0.7060.35
142_T385_V0.7060.35
99_C483_L0.7050.35
84_I586_A0.7040.35
274_F278_V0.7040.35
268_D291_L0.7010.35
309_S334_E0.7010.35
205_K209_D0.7000.35
313_A337_I0.7000.35
290_R491_V0.6990.35
368_G371_F0.6990.35
319_L333_T0.6990.35
24_A176_V0.6980.35
81_G132_V0.6960.35
611_F627_I0.6950.35
240_A244_L0.6950.35
293_R298_T0.6940.35
610_Y615_L0.6940.35
609_R613_Q0.6940.35
158_V258_I0.6930.34
224_L421_Y0.6910.34
141_L294_V0.6910.34
136_Q380_G0.6900.34
459_M492_G0.6880.34
39_A75_F0.6880.34
589_R594_T0.6880.34
487_L498_T0.6870.34
292_R302_E0.6860.34
269_T272_E0.6850.34
297_W341_E0.6850.34
38_W389_V0.6830.34
227_E473_N0.6810.34
135_I201_E0.6810.34
65_Y69_L0.6810.34
616_E627_I0.6800.34
316_R320_L0.6790.33
83_V93_L0.6770.33
91_A492_G0.6770.33
94_L358_F0.6750.33
88_M384_M0.6740.33
623_E631_P0.6740.33
57_E106_C0.6730.33
290_R363_L0.6730.33
467_N489_Q0.6720.33
535_K543_Y0.6720.33
94_L431_Q0.6710.33
28_G45_I0.6690.33
503_V528_T0.6690.33
187_Q190_L0.6690.33
313_A335_E0.6680.33
88_M143_P0.6680.33
386_M389_V0.6670.33
99_C356_V0.6670.33
598_V601_A0.6670.33
316_R333_T0.6660.33
309_S324_V0.6650.32
538_H574_R0.6650.32
119_Y132_V0.6650.32
25_L438_I0.6640.32
314_A330_I0.6640.32
57_E172_I0.6630.32
18_A437_C0.6630.32
330_I342_P0.6620.32
310_W315_T0.6620.32
14_A17_L0.6610.32
39_A417_L0.6610.32
217_L411_T0.6590.32
400_P496_A0.6580.32
322_R330_I0.6570.32
608_R619_E0.6550.32
111_S506_K0.6550.32
113_V116_E0.6540.32
62_A538_H0.6540.32
483_L516_L0.6510.31
317_Y331_N0.6480.31
16_K168_S0.6470.31
268_D517_N0.6470.31
497_F501_L0.6470.31
23_L163_A0.6450.31
449_I456_L0.6440.31
310_W313_A0.6440.31
313_A327_N0.6440.31
65_Y123_L0.6440.31
328_T341_E0.6430.31
249_I420_L0.6420.31
350_E518_Q0.6420.31
34_E425_I0.6420.31
296_A300_E0.6420.31
633_Q636_E0.6420.31
10_H449_I0.6410.31
319_L325_I0.6400.31
348_S544_Q0.6390.31
360_R505_D0.6390.31
269_T630_A0.6390.31
153_I421_Y0.6390.31
74_T123_L0.6380.31
151_S360_R0.6370.31
42_T458_S0.6370.31
403_V464_S0.6360.30
315_T324_V0.6360.30
259_Q262_R0.6350.30
88_M114_R0.6330.30
371_F375_T0.6320.30
144_Q148_E0.6320.30
464_S467_N0.6310.30
283_D294_V0.6310.30
130_I444_G0.6310.30
610_Y621_Y0.6300.30
364_S407_F0.6260.30
600_S607_R0.6260.30
612_G627_I0.6260.30
382_G489_Q0.6260.30
540_P543_Y0.6250.30
311_V328_T0.6240.30
441_A445_F0.6230.30
297_W301_R0.6230.30
259_Q263_P0.6220.30
288_L291_L0.6220.30
440_L444_G0.6210.29
90_R360_R0.6210.29
23_L162_M0.6210.29
294_V297_W0.6200.29
119_Y125_G0.6190.29
19_T296_A0.6180.29
536_E540_P0.6180.29
613_Q622_Q0.6180.29
394_A492_G0.6180.29
391_T500_I0.6170.29
296_A303_T0.6150.29
437_C502_L0.6150.29
162_M478_H0.6150.29
393_L463_A0.6120.29
611_F629_Q0.6120.29
74_T127_T0.6110.29
152_E373_L0.6110.29
100_C443_L0.6090.29
541_A548_L0.6080.29
336_E494_V0.6070.29
317_Y321_K0.6070.29
258_I324_V0.6050.28
92_P373_L0.6050.28
613_Q616_E0.6040.28
538_H543_Y0.6030.28
141_L362_T0.6030.28
164_D226_M0.6030.28
360_R375_T0.6030.28
499_V503_V0.6010.28
232_A238_L0.6010.28
292_R325_I0.6000.28
412_L616_E0.6000.28
32_Q463_A0.6000.28
80_A106_C0.6000.28
330_I343_E0.5980.28
592_R599_I0.5970.28
118_S123_L0.5970.28
534_R540_P0.5970.28
25_L29_F0.5960.28
289_K296_A0.5960.28
308_Y311_V0.5960.28
596_D600_S0.5960.28
17_L43_A0.5950.28
355_M359_W0.5950.28
593_R613_Q0.5940.28
104_G402_M0.5940.28
630_A637_P0.5930.28
297_W612_G0.5930.28
285_H288_L0.5930.28
275_D608_R0.5920.28
604_D624_K0.5920.28
319_L336_E0.5890.27
134_T426_I0.5880.27
102_W125_G0.5880.27
100_C104_G0.5880.27
43_A47_A0.5860.27
44_A421_Y0.5860.27
626_R632_P0.5860.27
207_W227_E0.5860.27
489_Q550_M0.5850.27
327_N331_N0.5850.27
101_I135_I0.5850.27
83_V259_Q0.5840.27
420_L428_N0.5840.27
25_L436_L0.5830.27
107_T402_M0.5830.27
263_P608_R0.5830.27
81_G131_I0.5820.27
114_R217_L0.5820.27
70_R427_P0.5820.27
283_D623_E0.5810.27
314_A321_K0.5810.27
218_Q246_L0.5800.27
14_A445_F0.5800.27
395_M505_D0.5790.27
605_D609_R0.5780.27
587_F599_I0.5780.27
46_V133_I0.5770.27
121_W453_K0.5760.27
125_G129_L0.5750.26
122_G504_R0.5750.26
292_R299_G0.5740.26
118_S467_N0.5730.26
38_W449_I0.5730.26
168_S389_V0.5730.26
199_D278_V0.5730.26
282_Q293_R0.5720.26
398_P551_N0.5710.26
110_S376_G0.5710.26
366_I375_T0.5710.26
593_R600_S0.5700.26
32_Q151_S0.5700.26
327_N343_E0.5680.26
297_W304_P0.5680.26
181_E270_F0.5680.26
361_T587_F0.5670.26
157_I427_P0.5660.26
129_L497_F0.5650.26
318_Q322_R0.5640.26
110_S153_I0.5640.26
360_R384_M0.5640.26
106_C129_L0.5640.26
426_I493_C0.5630.26
594_T603_S0.5630.26
324_V334_E0.5630.26
593_R597_H0.5630.26
106_C377_W0.5630.26
32_Q167_F0.5620.26
86_I89_I0.5610.26
152_E160_A0.5610.26
189_Q490_I0.5600.26
335_E587_F0.5590.25
240_A347_E0.5590.25
62_A224_L0.5590.25
273_F276_T0.5580.25
286_K289_K0.5570.25
364_S389_V0.5560.25
627_I636_E0.5560.25
313_A323_G0.5560.25
531_V581_N0.5560.25
325_I342_P0.5560.25
425_I573_L0.5550.25
241_I244_L0.5550.25
306_T314_A0.5540.25
310_W327_N0.5540.25
39_A80_A0.5540.25
185_V341_E0.5540.25
597_H614_L0.5540.25
286_K292_R0.5540.25
393_L496_A0.5540.25
360_R410_G0.5530.25
451_V462_L0.5530.25
311_V337_I0.5530.25
309_S313_A0.5520.25
196_K597_H0.5500.25
288_L302_E0.5500.25
421_Y512_G0.5500.25
462_L465_T0.5490.25
265_L341_E0.5490.25
45_I70_R0.5490.25
131_I142_T0.5490.25
248_L515_L0.5470.25
570_H614_L0.5470.25
307_I316_R0.5470.25
157_I394_A0.5470.25
322_R327_N0.5460.25
153_I441_A0.5460.25
596_D603_S0.5460.25
199_D623_E0.5450.25
464_S489_Q0.5450.25
383_A491_V0.5450.25
42_T134_T0.5450.25
267_T276_T0.5440.25
437_C440_L0.5440.25
199_D275_D0.5440.25
271_R297_W0.5440.25
111_S151_S0.5430.25
246_L485_S0.5420.24
258_I487_L0.5420.24
591_M600_S0.5410.24
584_L625_L0.5400.24
86_I116_E0.5390.24
276_T596_D0.5390.24
35_T62_A0.5390.24
122_G392_S0.5390.24
533_R546_L0.5380.24
573_L607_R0.5380.24
47_A69_L0.5380.24
113_V117_N0.5370.24
592_R620_I0.5370.24
17_L579_P0.5370.24
16_K113_V0.5360.24
549_L571_Q0.5360.24
362_T444_G0.5360.24
425_I587_F0.5360.24
93_L483_L0.5350.24
43_A65_Y0.5350.24
127_T377_W0.5350.24
264_E268_D0.5350.24
57_E220_M0.5350.24
341_E530_N0.5340.24
67_G371_F0.5340.24
153_I161_I0.5340.24
44_A226_M0.5340.24
605_D608_R0.5330.24
104_G435_L0.5320.24
340_G612_G0.5320.24
630_A636_E0.5310.24
347_E403_V0.5310.24
569_A572_R0.5300.24
328_T331_N0.5300.24
107_T391_T0.5300.24
447_L502_L0.5300.24
494_V502_L0.5300.24
90_R116_E0.5300.24
85_I447_L0.5300.24
92_P96_I0.5290.24
318_Q323_G0.5290.24
441_A459_M0.5280.24
42_T74_T0.5270.24
86_I113_V0.5270.24
275_D481_Q0.5270.24
160_A372_W0.5270.24
295_I304_P0.5260.24
157_I426_I0.5250.23
405_I409_Y0.5250.23
299_G309_S0.5250.23
627_I633_Q0.5240.23
35_T221_R0.5240.23
276_T293_R0.5230.23
536_E541_A0.5230.23
45_I126_Y0.5230.23
105_F415_L0.5230.23
269_T276_T0.5220.23
293_R613_Q0.5220.23
627_I630_A0.5220.23
516_L556_D0.5220.23
320_L324_V0.5210.23
425_I480_S0.5210.23
613_Q625_L0.5210.23
85_I307_I0.5210.23
16_K226_M0.5200.23
335_E339_Q0.5190.23
291_L496_A0.5190.23
33_L396_R0.5190.23
62_A207_W0.5180.23
590_Q633_Q0.5160.23
312_A327_N0.5150.23
438_I636_E0.5150.23
623_E629_Q0.5140.23
399_N500_I0.5130.23
181_E362_T0.5130.23
60_S226_M0.5130.23
306_T330_I0.5120.23
92_P377_W0.5120.23
28_G36_P0.5110.23
67_G161_I0.5110.23
79_I173_K0.5100.23
106_C499_V0.5100.23
119_Y156_G0.5100.23
314_A326_S0.5090.23
309_S326_S0.5080.23
620_I631_P0.5080.23
265_L281_A0.5080.23
157_I564_L0.5070.22
25_L546_L0.5070.22
102_W159_C0.5070.22
111_S358_F0.5050.22
448_G466_I0.5050.22
622_Q631_P0.5050.22
42_T377_W0.5050.22
277_P623_E0.5050.22
461_A479_F0.5050.22
127_T515_L0.5040.22
293_R300_E0.5030.22
612_G616_E0.5030.22
618_L628_W0.5020.22
329_K341_E0.5020.22
593_R596_D0.5020.22
534_R542_L0.5010.22
543_Y552_K0.5010.22
210_L495_L0.5010.22
169_P372_W0.5000.22
42_T127_T0.5000.22
601_A612_G0.5000.22
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2zz9A 3 0.2412 26 0.979 Contact Map
4k0jA 3 0.2412 17 0.981 Contact Map
3iyzA 3 0.2397 15.4 0.981 Contact Map
3d9sA 3 0.313 14.8 0.981 Contact Map
2zy9A 2 0.2366 14.6 0.981 Contact Map
3effK 4 0.1969 14.1 0.981 Contact Map
3pjsK 4 0.2015 13.2 0.982 Contact Map
4oj2X 3 0.2916 11.8 0.982 Contact Map
3cn5A 3 0.2427 11.3 0.982 Contact Map
3vouA 4 0.2015 11.1 0.982 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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