GSPE - ECOLI - GREMLIN Contacts

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GSPE - Putative type II secretion system protein E

UniProt:	P45759	Sequences: MRIHSPYPASWALAQRIGYLYSEGEIIYLADTPFERLLDIQRQVGQCQTMTSLSQADFEARLEAVFHQNTGESQQIAQDIDQSVDLLSLSEEMPANEDLLNEDSAAPVIRLINAILSEAIKETASDIHIETYEKTMSIRFRIDGVLRTILQPNKKLAALLISRIKVMARLDIAEKRIPQDGRISLRIGRRNIDVRVSTLPSIYGERAVLRLLDKNSLQLSLNNLGMTAADKQDLENLIQLPHGIILVTGPTGSGKSTTLYAILSALNTPGRNILTVEDPVEYELEGIGQTQVNTRVDMSFARGLRAILRQDPDVVMVGEIRDTETAQIAVQASLTGHLVLSTLHTNSASGAVTRLRDMGVESFLLSSSLAGIIAQRLVRRLCPQCRQFTPVSPQQAQMFKYHQLAVTTIGTPVGCPHCHQSGYQGRMAIHEMMVVTPELRAAIHENVDEQALERLVRQQHKALIKNGLQKVISGDTSWDEVMRVASATLESEA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12891
Length:	493 (468)
Sequences:	4266 (2920)
Seq/√Len:	135.0

ECOLI - GSPE HOFB
BACSU - COMGA
HALSA - Q9HQY3 Q9HR79
SULSO - Q97VE6 Q97WB7 Q7LXX6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
436_T	458_Q	4.946	1.00
381_L	412_P	4.901	1.00
234_L	262_I	4.161	1.00
237_L	371_G	4.032	1.00
387_Q	413_V	4.018	1.00
206_R	272_N	3.853	1.00
386_R	410_G	3.710	1.00
442_A	455_L	3.659	1.00
161_I	207_A	3.595	1.00
347_S	350_G	3.354	1.00
384_Q	417_H	3.347	1.00
388_F	408_T	3.304	1.00
271_R	314_V	3.256	1.00
235_E	265_A	3.122	1.00
387_Q	411_T	2.966	1.00
53_L	58_F	2.838	1.00
467_G	481_V	2.787	1.00
389_T	411_T	2.782	1.00
381_L	477_S	2.770	1.00
246_L	341_S	2.752	1.00
9_A	13_L	2.749	1.00
274_L	307_I	2.705	1.00
381_L	386_R	2.657	1.00
442_A	447_V	2.634	1.00
456_V	465_K	2.609	1.00
276_V	303_G	2.607	1.00
380_R	427_M	2.565	1.00
190_R	213_D	2.498	1.00
389_T	409_I	2.473	1.00
202_I	280_V	2.447	1.00
194_V	209_L	2.410	1.00
248_T	343_L	2.400	1.00
238_I	262_I	2.388	1.00
199_L	290_T	2.382	1.00
320_I	329_A	2.347	1.00
231_K	235_E	2.332	1.00
435_V	443_I	2.311	1.00
392_S	395_Q	2.249	1.00
427_M	475_D	2.222	1.00
112_I	160_L	2.218	1.00
466_N	470_K	2.215	1.00
373_I	432_M	2.210	1.00
136_M	157_A	2.204	1.00
177_I	296_V	2.184	1.00
26_I	49_T	2.146	1.00
438_E	458_Q	2.143	1.00
22_S	46_Q	2.088	1.00
206_R	288_G	2.088	1.00
236_N	434_V	2.083	1.00
123_T	424_Q	2.057	1.00
54_S	57_D	2.053	1.00
412_P	477_S	2.016	1.00
170_L	198_T	2.001	1.00
347_S	453_E	1.997	1.00
461_K	469_Q	1.990	1.00
168_A	196_V	1.948	1.00
197_S	310_Q	1.939	1.00
439_L	452_L	1.939	1.00
352_V	369_L	1.920	1.00
145_V	379_R	1.919	1.00
30_A	53_L	1.914	1.00
12_A	66_F	1.909	1.00
148_T	151_Q	1.906	1.00
349_S	433_M	1.876	1.00
391_V	409_I	1.847	1.00
230_D	430_H	1.825	1.00
40_I	48_Q	1.821	1.00
212_L	282_Y	1.819	1.00
441_A	445_E	1.809	1.00
11_W	15_Q	1.796	1.00
229_A	461_K	1.786	1.00
145_V	483_R	1.780	1.00
468_L	472_I	1.770	1.00
194_V	211_L	1.763	1.00
137_S	148_T	1.749	1.00
135_T	151_Q	1.732	1.00
230_D	432_M	1.713	1.00
469_Q	473_S	1.702	1.00
415_C	418_C	1.696	1.00
436_T	455_L	1.693	1.00
382_C	385_C	1.690	1.00
266_L	314_V	1.683	1.00
356_R	365_L	1.674	1.00
228_A	232_Q	1.667	1.00
448_D	451_A	1.665	1.00
240_L	370_A	1.663	1.00
427_M	470_K	1.639	1.00
384_Q	424_Q	1.635	1.00
201_S	288_G	1.629	1.00
385_C	418_C	1.626	1.00
226_M	430_H	1.625	1.00
230_D	466_N	1.623	1.00
198_T	207_A	1.616	1.00
227_T	230_D	1.615	1.00
464_I	485_A	1.599	1.00
164_I	196_V	1.587	1.00
382_C	418_C	1.586	1.00
245_I	338_L	1.582	1.00
385_C	415_C	1.571	1.00
299_S	302_R	1.555	1.00
20_L	51_T	1.553	1.00
28_Y	51_T	1.552	1.00
383_P	386_R	1.542	1.00
447_V	451_A	1.541	1.00
389_T	395_Q	1.535	1.00
293_N	296_V	1.531	1.00
276_V	307_I	1.514	1.00
455_L	458_Q	1.496	1.00
29_L	40_I	1.494	1.00
140_F	149_I	1.493	1.00
433_M	460_H	1.491	1.00
454_R	457_R	1.481	1.00
124_A	142_I	1.480	1.00
290_T	307_I	1.479	1.00
7_Y	12_A	1.472	1.00
409_I	471_V	1.467	1.00
129_I	136_M	1.466	1.00
130_E	139_R	1.465	1.00
462_A	465_K	1.463	1.00
382_C	415_C	1.462	1.00
327_Q	331_Q	1.461	1.00
388_F	410_G	1.448	1.00
21_Y	28_Y	1.448	1.00
266_L	340_L	1.435	1.00
470_K	475_D	1.432	1.00
230_D	233_D	1.427	1.00
34_F	38_L	1.427	1.00
471_V	481_V	1.414	1.00
12_A	62_L	1.408	1.00
438_E	457_R	1.400	1.00
18_G	58_F	1.384	1.00
148_T	269_P	1.378	1.00
112_I	164_I	1.372	1.00
246_L	320_I	1.372	1.00
16_R	59_E	1.366	1.00
25_E	46_Q	1.357	1.00
16_R	55_Q	1.355	1.00
381_L	413_V	1.353	1.00
320_I	341_S	1.353	1.00
267_N	273_I	1.342	1.00
206_R	274_L	1.330	1.00
145_V	270_G	1.328	1.00
445_E	451_A	1.311	1.00
237_L	432_M	1.309	1.00
245_I	371_G	1.306	1.00
27_I	44_V	1.297	1.00
326_A	360_V	1.294	1.00
232_Q	236_N	1.293	1.00
423_Y	476_T	1.292	1.00
13_L	63_E	1.291	1.00
37_L	50_M	1.289	1.00
250_P	376_R	1.286	1.00
437_P	440_R	1.283	1.00
381_L	410_G	1.283	1.00
220_S	223_N	1.277	1.00
411_T	479_D	1.271	1.00
393_P	397_Q	1.269	1.00
248_T	345_T	1.268	1.00
18_G	61_R	1.256	1.00
239_Q	265_A	1.250	1.00
20_L	30_A	1.236	1.00
303_G	307_I	1.232	1.00
372_I	433_M	1.227	1.00
229_A	233_D	1.224	1.00
330_V	360_V	1.222	1.00
251_T	312_P	1.221	1.00
226_M	258_T	1.220	1.00
233_D	434_V	1.213	1.00
349_S	452_L	1.208	1.00
378_V	476_T	1.188	0.99
222_N	231_K	1.188	0.99
244_I	339_V	1.187	0.99
334_L	364_L	1.184	0.99
118_E	122_E	1.175	0.99
331_Q	357_D	1.174	0.99
222_N	235_E	1.173	0.99
183_I	194_V	1.170	0.99
185_L	194_V	1.163	0.99
251_T	337_H	1.162	0.99
267_N	286_G	1.141	0.99
374_A	463_L	1.137	0.99
167_M	183_I	1.134	0.99
142_I	147_R	1.132	0.99
429_I	467_G	1.126	0.99
226_M	234_L	1.117	0.99
351_A	372_I	1.116	0.99
115_I	138_I	1.110	0.99
180_D	197_S	1.109	0.99
259_L	316_M	1.106	0.99
55_Q	59_E	1.095	0.99
331_Q	334_L	1.093	0.99
391_V	396_A	1.093	0.99
41_Q	47_C	1.092	0.99
456_V	460_H	1.091	0.99
356_R	362_S	1.085	0.99
120_I	192_I	1.084	0.99
28_Y	49_T	1.078	0.99
226_M	428_A	1.070	0.99
423_Y	477_S	1.068	0.99
407_T	472_I	1.067	0.99
476_T	480_E	1.066	0.99
236_N	240_L	1.065	0.99
7_Y	40_I	1.053	0.99
451_A	454_R	1.053	0.99
26_I	47_C	1.051	0.99
230_D	373_I	1.049	0.99
60_A	64_A	1.045	0.99
323_T	327_Q	1.043	0.99
379_R	480_E	1.038	0.99
414_G	418_C	1.034	0.99
165_K	205_E	1.033	0.99
30_A	51_T	1.031	0.99
15_Q	36_R	1.028	0.99
192_I	211_L	1.028	0.99
385_C	414_G	1.028	0.99
227_T	469_Q	1.026	0.98
20_L	28_Y	1.022	0.98
25_E	47_C	1.020	0.98
27_I	30_A	1.017	0.98
227_T	473_S	1.013	0.98
399_F	468_L	1.000	0.98
62_L	66_F	0.999	0.98
349_S	460_H	0.999	0.98
234_L	432_M	0.995	0.98
315_V	332_A	0.989	0.98
472_I	475_D	0.987	0.98
307_I	315_V	0.982	0.98
469_Q	472_I	0.980	0.98
197_S	208_V	0.978	0.98
119_A	140_F	0.975	0.98
36_R	40_I	0.974	0.98
301_A	324_E	0.969	0.98
186_R	191_N	0.965	0.98
115_I	127_I	0.964	0.98
272_N	288_G	0.964	0.98
237_L	370_A	0.962	0.98
17_I	36_R	0.957	0.98
248_T	351_A	0.955	0.98
78_Q	81_D	0.955	0.98
17_I	29_L	0.953	0.98
390_P	408_T	0.945	0.97
365_L	369_L	0.944	0.97
280_V	291_Q	0.939	0.97
276_V	292_V	0.938	0.97
305_R	324_E	0.936	0.97
349_S	453_E	0.934	0.97
154_K	157_A	0.928	0.97
471_V	478_W	0.928	0.97
132_Y	137_S	0.925	0.97
369_L	372_I	0.925	0.97
192_I	213_D	0.924	0.97
109_I	163_R	0.922	0.97
123_T	142_I	0.917	0.97
208_V	310_Q	0.917	0.97
276_V	290_T	0.916	0.97
391_V	395_Q	0.916	0.97
33_P	36_R	0.914	0.97
237_L	245_I	0.912	0.97
44_V	47_C	0.911	0.97
242_H	347_S	0.910	0.97
477_S	480_E	0.909	0.97
238_I	340_L	0.905	0.97
30_A	58_F	0.904	0.97
141_R	311_D	0.903	0.97
268_T	271_R	0.902	0.97
120_I	211_L	0.899	0.97
227_T	470_K	0.898	0.97
58_F	62_L	0.895	0.96
326_A	355_L	0.893	0.96
191_N	214_K	0.892	0.96
274_L	288_G	0.889	0.96
206_R	310_Q	0.888	0.96
170_L	207_A	0.887	0.96
468_L	471_V	0.886	0.96
143_D	379_R	0.885	0.96
17_I	40_I	0.878	0.96
439_L	455_L	0.877	0.96
356_R	446_N	0.875	0.96
177_I	298_M	0.874	0.96
441_A	454_R	0.864	0.96
304_L	328_I	0.864	0.96
115_I	129_I	0.863	0.96
24_G	46_Q	0.862	0.96
247_V	258_T	0.855	0.95
27_I	46_Q	0.854	0.95
116_L	194_V	0.853	0.95
22_S	25_E	0.852	0.95
380_R	475_D	0.851	0.95
395_Q	398_M	0.850	0.95
362_S	446_N	0.848	0.95
320_I	326_A	0.847	0.95
202_I	283_E	0.846	0.95
366_S	444_H	0.846	0.95
297_D	302_R	0.845	0.95
396_A	407_T	0.844	0.95
107_P	110_R	0.841	0.95
266_L	273_I	0.840	0.95
429_I	484_V	0.839	0.95
122_E	147_R	0.834	0.95
294_T	298_M	0.834	0.95
327_Q	361_E	0.834	0.95
8_P	11_W	0.833	0.95
429_I	485_A	0.831	0.95
41_Q	48_Q	0.830	0.95
40_I	44_V	0.825	0.94
256_S	260_Y	0.825	0.94
23_E	26_I	0.824	0.94
31_D	52_S	0.824	0.94
267_N	270_G	0.823	0.94
299_S	324_E	0.823	0.94
122_E	419_H	0.823	0.94
247_V	373_I	0.820	0.94
196_V	209_L	0.820	0.94
371_G	432_M	0.820	0.94
319_E	344_H	0.818	0.94
172_I	176_R	0.817	0.94
442_A	451_A	0.815	0.94
290_T	303_G	0.815	0.94
396_A	400_K	0.813	0.94
197_S	306_A	0.812	0.94
61_R	64_A	0.812	0.94
343_L	351_A	0.812	0.94
15_Q	39_D	0.808	0.94
403_Q	406_V	0.806	0.94
456_V	459_Q	0.806	0.94
39_D	42_R	0.801	0.93
435_V	439_L	0.801	0.93
135_T	285_E	0.797	0.93
221_L	231_K	0.797	0.93
396_A	401_Y	0.795	0.93
480_E	483_R	0.794	0.93
163_R	167_M	0.794	0.93
171_D	295_R	0.788	0.93
120_I	187_I	0.786	0.93
227_T	466_N	0.780	0.93
221_L	235_E	0.779	0.93
376_R	463_L	0.772	0.92
382_C	414_G	0.770	0.92
7_Y	19_Y	0.768	0.92
468_L	478_W	0.767	0.92
470_K	473_S	0.766	0.92
230_D	461_K	0.762	0.92
130_E	175_K	0.759	0.92
274_L	290_T	0.757	0.91
447_V	452_L	0.756	0.91
61_R	66_F	0.754	0.91
37_L	41_Q	0.752	0.91
259_L	340_L	0.751	0.91
242_H	370_A	0.749	0.91
309_R	319_E	0.749	0.91
476_T	481_V	0.747	0.91
349_S	449_E	0.746	0.91
309_R	344_H	0.744	0.91
456_V	462_A	0.744	0.91
304_L	307_I	0.744	0.91
352_V	443_I	0.742	0.91
126_D	344_H	0.742	0.91
24_G	49_T	0.741	0.91
193_D	214_K	0.738	0.90
378_V	429_I	0.736	0.90
466_N	469_Q	0.735	0.90
453_E	456_V	0.733	0.90
170_L	197_S	0.729	0.90
19_Y	22_S	0.727	0.90
125_S	208_V	0.724	0.90
409_I	412_P	0.724	0.90
260_Y	284_L	0.724	0.90
244_I	329_A	0.719	0.89
242_H	346_N	0.718	0.89
199_L	310_Q	0.717	0.89
112_I	167_M	0.717	0.89
23_E	28_Y	0.715	0.89
22_S	27_I	0.712	0.89
190_R	215_N	0.711	0.89
281_E	344_H	0.711	0.89
68_Q	72_E	0.710	0.89
238_I	245_I	0.708	0.88
330_V	364_L	0.706	0.88
272_N	310_Q	0.704	0.88
435_V	440_R	0.702	0.88
220_S	265_A	0.700	0.88
117_S	121_K	0.697	0.88
11_W	43_Q	0.695	0.88
255_K	344_H	0.692	0.87
213_D	217_L	0.691	0.87
342_T	345_T	0.691	0.87
128_H	311_D	0.690	0.87
168_A	183_I	0.690	0.87
25_E	28_Y	0.688	0.87
388_F	391_V	0.688	0.87
323_T	359_G	0.688	0.87
221_L	261_A	0.686	0.87
438_E	455_L	0.684	0.87
16_R	58_F	0.683	0.87
111_L	115_I	0.683	0.87
461_K	465_K	0.682	0.87
305_R	322_D	0.680	0.86
18_G	65_V	0.677	0.86
345_T	348_A	0.677	0.86
11_W	17_I	0.677	0.86
408_T	411_T	0.677	0.86
478_W	482_M	0.677	0.86
467_G	476_T	0.672	0.86
166_V	172_I	0.671	0.86
248_T	374_A	0.671	0.86
264_S	267_N	0.671	0.86
184_S	191_N	0.670	0.86
321_R	344_H	0.670	0.86
318_G	344_H	0.670	0.86
258_T	373_I	0.670	0.86
109_I	113_N	0.668	0.85
199_L	306_A	0.668	0.85
234_L	373_I	0.667	0.85
467_G	470_K	0.667	0.85
360_V	365_L	0.667	0.85
217_L	220_S	0.667	0.85
406_V	409_I	0.667	0.85
57_D	60_A	0.667	0.85
381_L	388_F	0.665	0.85
229_A	469_Q	0.663	0.85
378_V	427_M	0.663	0.85
245_I	370_A	0.662	0.85
126_D	309_R	0.662	0.85
357_D	444_H	0.660	0.85
183_I	196_V	0.660	0.85
182_R	193_D	0.659	0.85
124_A	140_F	0.659	0.85
113_N	163_R	0.658	0.85
395_Q	479_D	0.657	0.84
32_T	55_Q	0.656	0.84
438_E	442_A	0.656	0.84
437_P	454_R	0.655	0.84
88_S	92_E	0.653	0.84
298_M	303_G	0.652	0.84
26_I	46_Q	0.650	0.84
36_R	58_F	0.648	0.84
139_R	288_G	0.648	0.84
381_L	387_Q	0.648	0.84
468_L	481_V	0.647	0.84
12_A	19_Y	0.647	0.84
348_A	433_M	0.647	0.84
255_K	319_E	0.647	0.84
309_R	321_R	0.646	0.83
142_I	149_I	0.646	0.83
126_D	319_E	0.646	0.83
17_I	46_Q	0.646	0.83
164_I	209_L	0.645	0.83
256_S	284_L	0.642	0.83
19_Y	44_V	0.642	0.83
111_L	160_L	0.641	0.83
199_L	307_I	0.641	0.83
416_P	420_Q	0.640	0.83
317_V	328_I	0.639	0.83
308_L	332_A	0.639	0.83
15_Q	33_P	0.639	0.83
237_L	434_V	0.637	0.83
464_I	467_G	0.637	0.83
300_F	325_T	0.637	0.83
112_I	163_R	0.636	0.83
134_K	285_E	0.635	0.82
126_D	255_K	0.634	0.82
307_I	317_V	0.633	0.82
353_T	449_E	0.633	0.82
95_A	99_L	0.632	0.82
251_T	313_D	0.631	0.82
59_E	63_E	0.629	0.82
386_R	408_T	0.629	0.82
433_M	439_L	0.627	0.82
433_M	452_L	0.627	0.82
88_S	93_M	0.626	0.82
302_R	306_A	0.626	0.82
245_I	373_I	0.624	0.81
58_F	61_R	0.623	0.81
9_A	66_F	0.623	0.81
345_T	374_A	0.623	0.81
12_A	17_I	0.619	0.81
294_T	299_S	0.619	0.81
394_Q	398_M	0.619	0.81
164_I	207_A	0.618	0.81
322_D	325_T	0.618	0.81
431_E	460_H	0.616	0.80
229_A	232_Q	0.616	0.80
129_I	138_I	0.614	0.80
122_E	140_F	0.613	0.80
135_T	148_T	0.612	0.80
251_T	309_R	0.611	0.80
281_E	319_E	0.611	0.80
224_L	430_H	0.611	0.80
19_Y	29_L	0.610	0.80
89_L	93_M	0.610	0.80
251_T	319_E	0.610	0.80
121_K	188_G	0.609	0.80
234_L	238_I	0.609	0.80
9_A	12_A	0.608	0.80
141_R	313_D	0.608	0.80
136_M	161_I	0.606	0.79
234_L	245_I	0.606	0.79
7_Y	17_I	0.605	0.79
33_P	52_S	0.605	0.79
46_Q	50_M	0.604	0.79
39_D	43_Q	0.604	0.79
438_E	441_A	0.603	0.79
394_Q	397_Q	0.603	0.79
44_V	48_Q	0.603	0.79
396_A	406_V	0.602	0.79
116_L	127_I	0.601	0.79
251_T	321_R	0.598	0.79
389_T	392_S	0.598	0.79
434_V	460_H	0.597	0.78
131_T	161_I	0.596	0.78
267_N	271_R	0.596	0.78
132_Y	135_T	0.596	0.78
156_L	160_L	0.595	0.78
18_G	30_A	0.595	0.78
379_R	423_Y	0.594	0.78
69_N	72_E	0.594	0.78
14_A	39_D	0.594	0.78
177_I	302_R	0.592	0.78
133_E	203_Y	0.591	0.78
35_E	38_L	0.590	0.78
137_S	151_Q	0.590	0.78
157_A	161_I	0.589	0.77
214_K	282_Y	0.588	0.77
210_R	344_H	0.588	0.77
174_E	296_V	0.586	0.77
384_Q	416_P	0.586	0.77
347_S	431_E	0.585	0.77
429_I	470_K	0.585	0.77
228_A	231_K	0.584	0.77
441_A	450_Q	0.582	0.77
91_E	94_P	0.582	0.77
143_D	380_R	0.582	0.77
366_S	443_I	0.580	0.76
235_E	239_Q	0.580	0.76
126_D	279_P	0.579	0.76
237_L	373_I	0.578	0.76
251_T	335_T	0.578	0.76
290_T	298_M	0.577	0.76
247_V	259_L	0.577	0.76
100_L	103_D	0.576	0.76
296_V	302_R	0.576	0.76
347_S	463_L	0.576	0.76
257_T	282_Y	0.576	0.76
391_V	401_Y	0.576	0.76
208_V	311_D	0.575	0.76
256_S	282_Y	0.574	0.76
273_I	287_I	0.574	0.76
279_P	319_E	0.573	0.76
337_H	354_R	0.573	0.76
11_W	14_A	0.572	0.75
482_M	485_A	0.572	0.75
404_L	407_T	0.572	0.75
88_S	91_E	0.571	0.75
33_P	39_D	0.571	0.75
251_T	344_H	0.570	0.75
7_Y	11_W	0.569	0.75
166_V	170_L	0.569	0.75
241_P	346_N	0.568	0.75
129_I	157_A	0.568	0.75
130_E	288_G	0.567	0.75
203_Y	283_E	0.567	0.75
330_V	334_L	0.567	0.75
171_D	177_I	0.566	0.75
7_Y	10_S	0.566	0.75
449_E	453_E	0.566	0.75
176_R	296_V	0.566	0.75
51_T	57_D	0.566	0.75
278_D	291_Q	0.566	0.75
345_T	351_A	0.565	0.75
383_P	417_H	0.563	0.74
63_E	72_E	0.563	0.74
126_D	281_E	0.562	0.74
177_I	297_D	0.562	0.74
170_L	196_V	0.561	0.74
304_L	317_V	0.560	0.74
266_L	271_R	0.560	0.74
171_D	176_R	0.559	0.74
212_L	251_T	0.558	0.74
276_V	328_I	0.557	0.73
37_L	48_Q	0.557	0.73
335_T	344_H	0.557	0.73
279_P	344_H	0.556	0.73
452_L	455_L	0.556	0.73
29_L	50_M	0.555	0.73
418_C	422_G	0.555	0.73
236_N	417_H	0.555	0.73
136_M	160_L	0.555	0.73
213_D	260_Y	0.554	0.73
362_S	443_I	0.554	0.73
165_K	179_Q	0.553	0.73
33_P	37_L	0.552	0.73
450_Q	454_R	0.551	0.73
101_N	104_S	0.551	0.73
113_N	167_M	0.551	0.73
30_A	50_M	0.549	0.72
244_I	371_G	0.549	0.72
378_V	467_G	0.548	0.72
12_A	65_V	0.547	0.72
165_K	181_G	0.547	0.72
304_L	308_L	0.547	0.72
252_G	322_D	0.546	0.72
130_E	272_N	0.545	0.72
298_M	306_A	0.544	0.72
126_D	251_T	0.543	0.72
126_D	321_R	0.543	0.72
396_A	399_F	0.543	0.72
16_R	53_L	0.543	0.72
315_V	337_H	0.541	0.71
165_K	168_A	0.541	0.71
196_V	207_A	0.540	0.71
122_E	142_I	0.540	0.71
18_G	54_S	0.540	0.71
56_A	59_E	0.539	0.71
126_D	210_R	0.539	0.71
210_R	309_R	0.539	0.71
312_P	337_H	0.539	0.71
249_G	318_G	0.538	0.71
388_F	407_T	0.538	0.71
409_I	472_I	0.536	0.71
349_S	353_T	0.536	0.71
20_L	58_F	0.535	0.71
185_L	211_L	0.535	0.71
143_D	424_Q	0.535	0.71
184_S	194_V	0.534	0.70
227_T	461_K	0.533	0.70
110_R	295_R	0.533	0.70
90_S	93_M	0.533	0.70
137_S	269_P	0.532	0.70
43_Q	46_Q	0.532	0.70
392_S	398_M	0.532	0.70
23_E	49_T	0.532	0.70
319_E	335_T	0.531	0.70
128_H	195_R	0.531	0.70
233_D	236_N	0.530	0.70
249_G	336_G	0.530	0.70
170_L	181_G	0.529	0.70
118_E	140_F	0.529	0.70
210_R	319_E	0.529	0.70
275_T	282_Y	0.529	0.70
210_R	321_R	0.528	0.70
162_S	172_I	0.528	0.70
118_E	150_L	0.526	0.69
53_L	57_D	0.525	0.69
90_S	94_P	0.525	0.69
166_V	272_N	0.525	0.69
195_R	344_H	0.524	0.69
256_S	361_E	0.524	0.69
10_S	14_A	0.523	0.69
102_E	105_A	0.523	0.69
255_K	309_R	0.523	0.69
318_G	336_G	0.523	0.69
68_Q	71_G	0.523	0.69
125_S	426_R	0.522	0.69
30_A	61_R	0.521	0.69
213_D	282_Y	0.520	0.68
180_D	346_N	0.520	0.68
463_L	467_G	0.520	0.68
252_G	318_G	0.518	0.68
116_L	185_L	0.518	0.68
56_A	60_A	0.518	0.68
358_M	430_H	0.518	0.68
284_L	287_I	0.517	0.68
24_G	29_L	0.517	0.68
143_D	426_R	0.516	0.68
263_L	287_I	0.516	0.68
38_L	41_Q	0.515	0.68
222_N	228_A	0.515	0.68
178_P	325_T	0.515	0.68
281_E	321_R	0.515	0.68
59_E	62_L	0.514	0.67
99_L	102_E	0.514	0.67
126_D	195_R	0.514	0.67
244_I	330_V	0.513	0.67
415_C	422_G	0.512	0.67
54_S	61_R	0.511	0.67
93_M	97_E	0.510	0.67
118_E	121_K	0.510	0.67
328_I	368_S	0.510	0.67
335_T	346_N	0.509	0.67
264_S	284_L	0.509	0.67
300_F	318_G	0.508	0.67
40_I	54_S	0.508	0.67
89_L	94_P	0.507	0.66
23_E	46_Q	0.507	0.66
20_L	49_T	0.506	0.66
405_A	408_T	0.506	0.66
213_D	216_S	0.506	0.66
225_G	230_D	0.505	0.66
309_R	335_T	0.504	0.66
384_Q	478_W	0.504	0.66
350_G	353_T	0.504	0.66
334_L	368_S	0.504	0.66
40_I	43_Q	0.503	0.66
225_G	428_A	0.503	0.66
461_K	466_N	0.503	0.66
131_T	310_Q	0.502	0.66
443_I	452_L	0.502	0.66
132_Y	286_G	0.502	0.66
147_R	419_H	0.502	0.66
396_A	409_I	0.501	0.66
467_G	471_V	0.501	0.66
433_M	462_A	0.500	0.65

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4phtA	1	0.8884	100	0.266	Contact Map
4ksrA	3	0.7404	100	0.353	Contact Map
1p9rA	1	0.7667	100	0.377	Contact Map
2ewvA	3	0.6592	100	0.563	Contact Map
3jvvA	3	0.6511	100	0.574	Contact Map
2oap1	3	0.8945	100	0.633	Contact Map
4ihqA	3	0.9229	100	0.675	Contact Map
2eyuA	1	0.4645	100	0.687	Contact Map
4bloA	4	0.5274	100	0.714	Contact Map
2gzaA	3	0.5761	100	0.777	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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