FRLA - ECOLI - GREMLIN Contacts

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FRLA - Putative fructoselysine transporter FrlA

UniProt:	P45539	Sequences: MGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12908
Length:	445 (418)
Sequences:	24647 (16064)
Seq/√Len:	785.7

ECOLI - FRLA AROP PROY ADIC POTE PUUP ANSP GABP LYSP YIFK PLAP MMUP YCAM PHEP YBAT YJEM YGJI CYCA ARCD GADC CADB YJEH TNAB MTR
BACSU - YBXG YTNA YHDG YFNA GABP YVBW ASPP STET ROCC YDGF YBEC HUTM YBGF AAPA ARCD ROCE YCGH YECA YDAO GERAB YNDE GERBB GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97XM0 Q97U05 Q7LXI7 Q97X49 Q97WS3 Q97VA6 Q97ZB5 Q97Z63 Q97WD4 Q97U33 Q97VA8 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
139_M	338_G	4.366	1.00
319_C	332_V	4.314	1.00
366_T	398_I	3.174	1.00
53_G	240_L	3.168	1.00
322_H	332_V	3.056	1.00
226_K	230_R	2.932	1.00
324_H	327_Y	2.929	1.00
374_W	377_K	2.907	1.00
11_G	222_K	2.823	1.00
221_I	227_T	2.749	1.00
77_Y	313_D	2.709	1.00
223_N	226_K	2.705	1.00
93_G	310_M	2.619	1.00
311_A	321_G	2.608	1.00
324_H	331_D	2.568	1.00
171_G	249_V	2.547	1.00
319_C	322_H	2.492	1.00
16_L	234_G	2.450	1.00
132_A	342_I	2.448	1.00
169_G	173_F	2.392	1.00
255_P	258_K	2.388	1.00
279_T	283_F	2.336	1.00
12_F	234_G	2.318	1.00
219_G	312_K	2.296	1.00
65_E	376_R	2.275	1.00
220_E	305_R	2.249	1.00
268_D	271_T	2.206	1.00
369_F	397_A	2.201	1.00
81_K	89_A	2.179	1.00
308_Y	312_K	2.142	1.00
335_I	339_A	2.117	1.00
380_D	383_P	2.108	1.00
140_L	144_R	2.103	1.00
15_V	221_I	2.100	1.00
136_I	342_I	2.091	1.00
423_V	427_G	2.076	1.00
143_L	331_D	2.073	1.00
12_F	227_T	2.072	1.00
147_E	151_A	2.067	1.00
139_M	334_I	2.060	1.00
395_T	399_A	2.059	1.00
12_F	16_L	2.055	1.00
379_D	383_P	2.025	1.00
132_A	345_I	1.976	1.00
131_A	345_I	1.973	1.00
81_K	86_R	1.965	1.00
230_R	234_G	1.960	1.00
158_I	162_I	1.933	1.00
84_G	374_W	1.931	1.00
320_F	336_L	1.920	1.00
97_F	337_Q	1.912	1.00
258_K	272_W	1.900	1.00
62_V	369_F	1.900	1.00
11_G	14_A	1.889	1.00
314_N	318_K	1.887	1.00
176_K	180_F	1.884	1.00
35_V	45_T	1.884	1.00
429_P	433_F	1.875	1.00
54_L	58_P	1.829	1.00
136_I	338_G	1.780	1.00
16_L	238_L	1.770	1.00
84_G	370_G	1.749	1.00
223_N	227_T	1.723	1.00
80_L	92_S	1.711	1.00
14_A	154_T	1.710	1.00
85_S	88_L	1.695	1.00
233_I	237_L	1.691	1.00
392_L	396_L	1.676	1.00
399_A	403_I	1.676	1.00
142_H	297_S	1.676	1.00
370_G	398_I	1.670	1.00
190_A	193_S	1.668	1.00
421_V	425_A	1.662	1.00
19_A	235_S	1.634	1.00
268_D	272_W	1.623	1.00
413_P	416_G	1.616	1.00
327_Y	331_D	1.614	1.00
92_S	367_L	1.609	1.00
262_S	268_D	1.607	1.00
143_L	335_I	1.596	1.00
135_I	341_G	1.593	1.00
109_A	296_L	1.588	1.00
48_A	200_G	1.587	1.00
379_D	382_K	1.581	1.00
324_H	329_T	1.581	1.00
126_L	129_F	1.567	1.00
94_W	427_G	1.555	1.00
105_L	341_G	1.552	1.00
162_I	166_I	1.548	1.00
7_Q	328_N	1.546	1.00
10_L	14_A	1.543	1.00
116_L	130_I	1.540	1.00
262_S	265_P	1.520	1.00
308_Y	323_V	1.510	1.00
55_I	400_S	1.500	1.00
54_L	396_L	1.498	1.00
84_G	88_L	1.487	1.00
179_N	182_A	1.482	1.00
144_R	327_Y	1.476	1.00
307_E	333_S	1.444	1.00
163_P	287_T	1.437	1.00
303_Q	337_Q	1.434	1.00
60_M	236_C	1.434	1.00
58_P	396_L	1.433	1.00
176_K	179_N	1.422	1.00
414_I	417_L	1.420	1.00
112_I	289_M	1.418	1.00
52_G	204_T	1.417	1.00
237_L	241_V	1.415	1.00
370_G	374_W	1.414	1.00
217_M	301_M	1.400	1.00
80_L	367_L	1.399	1.00
271_T	281_G	1.389	1.00
224_P	229_P	1.387	1.00
139_M	335_I	1.382	1.00
125_L	129_F	1.380	1.00
318_K	321_G	1.378	1.00
332_V	336_L	1.373	1.00
389_A	393_M	1.373	1.00
318_K	322_H	1.363	1.00
322_H	331_D	1.363	1.00
177_A	180_F	1.363	1.00
135_I	338_G	1.359	1.00
172_I	249_V	1.359	1.00
304_P	334_I	1.349	1.00
282_I	286_I	1.341	1.00
73_N	219_G	1.339	1.00
422_I	426_T	1.338	1.00
87_P	434_W	1.333	1.00
112_I	134_L	1.324	1.00
223_N	230_R	1.323	1.00
132_A	136_I	1.320	1.00
70_Y	82_N	1.319	1.00
414_I	418_I	1.317	1.00
109_A	135_I	1.312	1.00
227_T	230_R	1.311	1.00
59_Q	369_F	1.308	1.00
60_M	232_L	1.307	1.00
138_F	296_L	1.304	1.00
14_A	150_A	1.299	1.00
161_I	165_T	1.296	1.00
83_A	371_S	1.287	1.00
168_I	245_L	1.271	1.00
12_F	230_R	1.264	1.00
171_G	253_L	1.263	1.00
46_V	248_L	1.255	1.00
427_G	430_A	1.253	1.00
123_D	126_L	1.248	1.00
23_T	239_V	1.247	1.00
366_T	402_L	1.245	1.00
62_V	394_T	1.239	1.00
10_L	15_V	1.234	1.00
390_F	394_T	1.231	1.00
61_C	233_I	1.229	1.00
241_V	245_L	1.227	1.00
78_V	82_N	1.221	1.00
428_L	432_A	1.220	1.00
391_G	395_T	1.216	1.00
97_F	307_E	1.210	1.00
413_P	417_L	1.210	1.00
373_I	395_T	1.204	1.00
222_K	227_T	1.196	1.00
178_E	181_A	1.190	1.00
175_F	179_N	1.187	1.00
30_V	111_A	1.185	1.00
167_V	171_G	1.182	1.00
128_K	132_A	1.175	1.00
15_V	231_A	1.171	1.00
10_L	150_A	1.170	1.00
175_F	178_E	1.165	1.00
108_M	295_S	1.164	1.00
63_Y	76_D	1.162	1.00
415_P	418_I	1.156	1.00
307_E	316_F	1.153	1.00
402_L	406_A	1.152	1.00
264_T	268_D	1.152	1.00
417_L	420_A	1.147	1.00
392_L	395_T	1.146	1.00
13_W	17_A	1.146	1.00
378_R	381_Y	1.137	1.00
72_E	78_V	1.130	1.00
9_K	222_K	1.125	1.00
425_A	429_P	1.125	1.00
36_A	45_T	1.117	1.00
332_V	335_I	1.115	1.00
141_L	152_F	1.104	1.00
430_A	434_W	1.100	1.00
312_K	321_G	1.091	1.00
430_A	433_F	1.081	1.00
152_F	156_I	1.080	1.00
174_W	180_F	1.080	1.00
90_F	94_W	1.068	1.00
67_S	79_Y	1.064	1.00
19_A	214_I	1.063	1.00
418_I	422_I	1.061	1.00
174_W	177_A	1.059	1.00
133_G	137_A	1.048	1.00
175_F	252_G	1.047	1.00
403_I	407_S	1.045	1.00
151_A	155_L	1.044	1.00
20_V	238_L	1.042	1.00
198_L	403_I	1.042	1.00
80_L	88_L	1.041	1.00
82_N	378_R	1.041	1.00
139_M	143_L	1.037	1.00
372_I	394_T	1.034	1.00
420_A	424_I	1.033	1.00
323_V	328_N	1.032	1.00
153_Q	297_S	1.024	1.00
72_E	82_N	1.016	1.00
166_I	170_L	1.015	1.00
423_V	430_A	1.015	1.00
18_I	217_M	1.014	1.00
183_P	186_T	1.011	1.00
129_F	133_G	1.011	1.00
65_E	68_T	1.009	1.00
190_A	197_L	1.007	1.00
339_A	343_F	1.005	1.00
415_P	419_C	0.999	1.00
418_I	421_V	0.995	1.00
116_L	289_M	0.985	1.00
77_Y	309_A	0.985	1.00
113_V	130_I	0.978	1.00
69_A	381_Y	0.975	1.00
50_V	244_T	0.973	1.00
398_I	402_L	0.971	1.00
20_V	239_V	0.970	1.00
218_T	228_M	0.969	1.00
414_I	427_G	0.965	1.00
136_I	140_L	0.965	1.00
143_L	329_T	0.963	1.00
175_F	180_F	0.959	1.00
416_G	420_A	0.950	1.00
414_I	421_V	0.950	1.00
366_T	401_S	0.950	1.00
417_L	421_V	0.947	1.00
156_I	294_G	0.946	1.00
276_L	280_A	0.945	1.00
271_T	278_S	0.943	1.00
168_I	249_V	0.938	1.00
137_A	293_L	0.937	1.00
146_V	301_M	0.934	1.00
248_L	252_G	0.930	1.00
416_G	421_V	0.929	1.00
69_A	383_P	0.926	1.00
265_P	268_D	0.924	1.00
209_T	361_M	0.923	1.00
116_L	120_T	0.922	1.00
165_T	169_G	0.920	1.00
17_A	154_T	0.919	1.00
193_S	196_A	0.918	1.00
373_I	394_T	0.918	1.00
143_L	324_H	0.912	1.00
234_G	238_L	0.911	1.00
266_I	269_A	0.911	1.00
74_G	77_Y	0.903	1.00
300_V	338_G	0.899	1.00
81_K	313_D	0.899	1.00
419_C	422_I	0.898	1.00
278_S	282_I	0.897	1.00
178_E	182_A	0.893	1.00
377_K	380_D	0.892	1.00
24_V	27_G	0.891	1.00
432_A	435_A	0.891	1.00
331_D	335_I	0.889	1.00
240_L	244_T	0.888	1.00
386_R	389_A	0.888	1.00
46_V	251_S	0.886	1.00
212_A	216_Y	0.884	1.00
58_P	393_M	0.884	1.00
68_T	384_L	0.884	1.00
107_I	206_W	0.881	1.00
277_G	280_A	0.880	1.00
138_F	297_S	0.880	1.00
427_G	431_Y	0.880	1.00
366_T	370_G	0.878	1.00
168_I	172_I	0.877	1.00
9_K	147_E	0.876	1.00
69_A	384_L	0.876	1.00
161_I	242_L	0.874	1.00
94_W	316_F	0.873	1.00
85_S	435_A	0.870	1.00
320_F	332_V	0.870	1.00
138_F	300_V	0.866	1.00
14_A	151_A	0.864	1.00
74_G	78_V	0.861	1.00
265_P	270_L	0.859	1.00
369_F	398_I	0.853	1.00
187_A	191_T	0.846	1.00
415_P	427_G	0.844	1.00
112_I	292_I	0.838	1.00
130_I	133_G	0.834	1.00
13_W	154_T	0.830	1.00
416_G	423_V	0.827	1.00
107_I	354_L	0.826	1.00
151_A	154_T	0.825	1.00
35_V	39_A	0.824	1.00
185_T	188_I	0.820	1.00
359_L	420_A	0.819	1.00
213_S	302_Y	0.816	1.00
88_L	367_L	0.811	1.00
124_P	127_G	0.809	1.00
39_A	42_P	0.808	1.00
275_A	278_S	0.808	1.00
53_G	208_Y	0.807	1.00
24_V	29_F	0.806	1.00
401_S	404_L	0.804	1.00
112_I	293_L	0.803	1.00
194_F	197_L	0.802	1.00
316_F	320_F	0.802	1.00
338_G	342_I	0.802	1.00
160_K	291_V	0.791	1.00
135_I	345_I	0.788	1.00
415_P	421_V	0.788	1.00
57_I	61_C	0.788	1.00
420_A	423_V	0.788	1.00
87_P	91_L	0.786	1.00
113_V	131_A	0.786	1.00
80_L	371_S	0.782	1.00
173_F	177_A	0.781	1.00
172_I	245_L	0.781	1.00
339_A	342_I	0.779	1.00
12_F	231_A	0.778	1.00
183_P	187_A	0.775	1.00
431_Y	435_A	0.775	1.00
167_V	270_L	0.772	1.00
66_L	372_I	0.771	1.00
428_L	431_Y	0.770	1.00
50_V	54_L	0.768	1.00
416_G	419_C	0.767	1.00
173_F	176_K	0.766	1.00
385_W	388_P	0.764	1.00
419_C	423_V	0.764	1.00
414_I	423_V	0.758	1.00
57_I	233_I	0.756	1.00
28_I	246_L	0.754	1.00
424_I	428_L	0.753	1.00
356_Y	360_V	0.751	1.00
188_I	191_T	0.746	1.00
13_W	151_A	0.745	1.00
16_L	231_A	0.741	1.00
255_P	272_W	0.740	1.00
360_V	364_K	0.739	1.00
209_T	365_N	0.738	1.00
113_V	127_G	0.735	1.00
87_P	428_L	0.735	1.00
77_Y	81_K	0.734	1.00
324_H	328_N	0.733	1.00
110_L	353_L	0.732	1.00
330_P	333_S	0.731	1.00
223_N	229_P	0.730	1.00
378_R	383_P	0.729	1.00
405_V	408_T	0.729	1.00
47_L	197_L	0.726	1.00
9_K	146_V	0.725	1.00
45_T	247_A	0.724	1.00
229_P	232_L	0.724	1.00
199_A	203_A	0.724	1.00
253_L	269_A	0.723	1.00
58_P	62_V	0.722	1.00
113_V	116_L	0.721	1.00
24_V	160_K	0.720	1.00
140_L	143_L	0.716	1.00
177_A	181_A	0.716	1.00
42_P	190_A	0.716	1.00
128_K	345_I	0.715	1.00
83_A	374_W	0.715	1.00
416_G	427_G	0.714	1.00
144_R	148_G	0.714	1.00
66_L	79_Y	0.712	1.00
422_I	425_A	0.711	1.00
104_S	107_I	0.710	1.00
372_I	376_R	0.708	1.00
128_K	131_A	0.708	1.00
414_I	420_A	0.707	1.00
421_V	424_I	0.705	1.00
58_P	397_A	0.705	1.00
174_W	178_E	0.703	1.00
117_G	121_P	0.702	1.00
225_G	384_L	0.701	1.00
279_T	282_I	0.701	1.00
311_A	320_F	0.698	1.00
305_R	308_Y	0.698	1.00
264_T	267_S	0.696	1.00
320_F	333_S	0.696	1.00
118_F	121_P	0.694	1.00
397_A	401_S	0.693	1.00
132_A	346_F	0.692	1.00
172_I	176_K	0.692	1.00
21_G	157_T	0.690	1.00
300_V	304_P	0.689	1.00
238_L	242_L	0.686	1.00
95_A	364_K	0.686	1.00
245_L	249_V	0.686	1.00
415_P	420_A	0.686	1.00
41_T	251_S	0.684	1.00
117_G	127_G	0.680	1.00
104_S	108_M	0.679	1.00
371_S	375_C	0.678	1.00
326_K	331_D	0.678	1.00
59_Q	401_S	0.677	1.00
426_T	429_P	0.677	1.00
23_T	235_S	0.677	1.00
142_H	334_I	0.677	1.00
143_L	327_Y	0.676	1.00
429_P	432_A	0.676	1.00
307_E	336_L	0.676	1.00
150_A	154_T	0.675	1.00
47_L	51_I	0.673	1.00
170_L	277_G	0.673	1.00
84_G	371_S	0.670	1.00
177_A	182_A	0.670	1.00
142_H	301_M	0.670	1.00
73_N	308_Y	0.667	1.00
63_Y	368_T	0.665	1.00
394_T	398_I	0.664	1.00
219_G	308_Y	0.664	1.00
418_I	423_V	0.662	1.00
99_A	361_M	0.662	1.00
194_F	198_L	0.659	1.00
397_A	400_S	0.658	1.00
304_P	333_S	0.658	1.00
47_L	50_V	0.658	1.00
168_I	246_L	0.656	1.00
83_A	375_C	0.655	1.00
77_Y	93_G	0.655	1.00
373_I	391_G	0.654	1.00
390_F	393_M	0.653	1.00
196_A	199_A	0.653	1.00
266_I	270_L	0.651	1.00
265_P	269_A	0.650	1.00
9_K	13_W	0.648	1.00
104_S	357_F	0.648	1.00
413_P	421_V	0.648	1.00
431_Y	434_W	0.648	1.00
96_S	100_N	0.647	1.00
398_I	401_S	0.646	1.00
426_T	430_A	0.646	1.00
102_A	340_L	0.643	1.00
42_P	45_T	0.643	1.00
136_I	139_M	0.640	1.00
319_C	336_L	0.639	1.00
109_A	113_V	0.639	1.00
143_L	334_I	0.639	1.00
417_L	431_Y	0.638	1.00
106_S	353_L	0.637	1.00
403_I	406_A	0.637	1.00
138_F	293_L	0.637	1.00
32_V	247_A	0.636	1.00
413_P	418_I	0.636	1.00
401_S	405_V	0.634	1.00
220_E	323_V	0.634	1.00
423_V	428_L	0.634	1.00
391_G	394_T	0.632	1.00
56_V	211_M	0.632	1.00
388_P	392_L	0.630	1.00
19_A	23_T	0.629	1.00
84_G	87_P	0.629	1.00
42_P	197_L	0.628	1.00
421_V	430_A	0.625	1.00
283_F	287_T	0.624	1.00
246_L	250_I	0.623	1.00
46_V	50_V	0.622	1.00
106_S	344_F	0.621	1.00
62_V	397_A	0.619	1.00
234_G	237_L	0.619	1.00
220_E	330_P	0.618	1.00
228_M	232_L	0.618	1.00
148_G	151_A	0.617	1.00
421_V	428_L	0.617	1.00
49_F	207_S	0.616	1.00
413_P	420_A	0.612	1.00
216_Y	302_Y	0.612	1.00
65_E	388_P	0.610	1.00
415_P	423_V	0.610	1.00
359_L	405_V	0.610	1.00
390_F	395_T	0.610	1.00
174_W	179_N	0.609	1.00
115_N	288_A	0.609	1.00
67_S	228_M	0.609	1.00
266_I	271_T	0.608	1.00
22_T	299_C	0.608	1.00
60_M	211_M	0.608	1.00
134_L	296_L	0.608	1.00
22_T	298_S	0.607	1.00
159_A	287_T	0.603	1.00
64_A	68_T	0.602	1.00
400_S	404_L	0.601	1.00
31_S	354_L	0.600	1.00
404_L	408_T	0.600	1.00
186_T	191_T	0.598	1.00
422_I	427_G	0.597	1.00
66_L	83_A	0.597	1.00
399_A	402_L	0.597	1.00
189_G	193_S	0.593	1.00
430_A	435_A	0.593	1.00
417_L	422_I	0.592	1.00
116_L	134_L	0.592	1.00
215_C	232_L	0.591	1.00
25_G	29_F	0.590	1.00
184_T	188_I	0.589	1.00
135_I	342_I	0.588	1.00
108_M	296_L	0.588	1.00
51_I	201_I	0.587	1.00
87_P	432_A	0.587	1.00
389_A	392_L	0.585	1.00
146_V	217_M	0.584	1.00
198_L	407_S	0.582	1.00
414_I	430_A	0.582	1.00
148_G	152_F	0.581	1.00
267_S	270_L	0.581	1.00
291_V	294_G	0.579	1.00
108_M	111_A	0.579	1.00
95_A	363_F	0.578	1.00
305_R	323_V	0.577	1.00
112_I	116_L	0.576	1.00
100_N	299_C	0.575	1.00
76_D	212_A	0.575	1.00
209_T	212_A	0.574	1.00
85_S	89_A	0.573	1.00
425_A	428_L	0.572	1.00
413_P	423_V	0.571	1.00
413_P	430_A	0.571	1.00
13_W	16_L	0.570	1.00
413_P	419_C	0.569	1.00
77_Y	89_A	0.567	1.00
46_V	244_T	0.565	1.00
249_V	252_G	0.565	1.00
221_I	228_M	0.565	1.00
224_P	227_T	0.565	1.00
111_A	115_N	0.565	1.00
267_S	271_T	0.564	1.00
119_L	286_I	0.564	1.00
255_P	259_L	0.564	1.00
67_S	215_C	0.563	1.00
139_M	300_V	0.563	1.00
303_Q	307_E	0.563	1.00
145_S	148_G	0.563	1.00
125_L	130_I	0.562	1.00
422_I	433_F	0.561	1.00
76_D	216_Y	0.560	1.00
150_A	297_S	0.560	1.00
198_L	202_S	0.560	1.00
187_A	190_A	0.560	1.00
118_F	285_A	0.559	1.00
256_F	259_L	0.558	1.00
180_F	251_S	0.556	1.00
149_G	301_M	0.555	1.00
61_C	393_M	0.553	1.00
20_V	157_T	0.552	1.00
336_L	340_L	0.550	1.00
246_L	266_I	0.549	1.00
106_S	109_A	0.548	1.00
15_V	217_M	0.548	1.00
238_L	241_V	0.545	1.00
350_L	354_L	0.541	1.00
60_M	64_A	0.541	1.00
319_C	323_V	0.541	1.00
154_T	158_I	0.541	1.00
286_I	290_I	0.540	1.00
343_F	346_F	0.539	1.00
35_V	204_T	0.539	1.00
16_L	19_A	0.539	1.00
361_M	364_K	0.539	1.00
305_R	330_P	0.538	1.00
127_G	131_A	0.537	1.00
415_P	430_A	0.535	1.00
180_F	252_G	0.534	1.00
109_A	112_I	0.533	1.00
417_L	430_A	0.533	1.00
417_L	427_G	0.533	1.00
52_G	208_Y	0.533	1.00
103_P	356_Y	0.532	1.00
11_G	147_E	0.532	1.00
389_A	394_T	0.532	1.00
375_C	378_R	0.532	1.00
162_I	165_T	0.530	1.00
323_V	327_Y	0.529	1.00
423_V	431_Y	0.528	1.00
62_V	387_T	0.528	1.00
225_G	230_R	0.527	1.00
133_G	136_I	0.527	1.00
422_I	429_P	0.527	1.00
159_A	163_P	0.524	1.00
52_G	205_S	0.523	1.00
120_T	124_P	0.522	1.00
157_T	160_K	0.520	1.00
185_T	189_G	0.519	1.00
238_L	245_L	0.519	1.00
108_M	292_I	0.519	1.00
362_C	401_S	0.519	1.00
226_K	229_P	0.517	1.00
420_A	430_A	0.516	1.00
176_K	181_A	0.515	1.00
72_E	219_G	0.515	1.00
61_C	388_P	0.514	1.00
423_V	429_P	0.514	1.00
80_L	89_A	0.514	1.00
331_D	334_I	0.514	1.00
209_T	357_F	0.514	1.00
119_L	285_A	0.513	1.00
186_T	189_G	0.513	1.00
65_E	69_A	0.513	1.00
376_R	379_D	0.513	1.00
115_N	267_S	0.511	1.00
189_G	192_G	0.510	1.00
22_T	213_S	0.510	1.00
25_G	243_Y	0.510	1.00
416_G	430_A	0.509	1.00
114_S	127_G	0.509	1.00
415_P	432_A	0.508	1.00
351_T	354_L	0.507	1.00
49_F	247_A	0.507	1.00
420_A	425_A	0.506	1.00
296_L	299_C	0.506	1.00
381_Y	384_L	0.506	1.00
349_D	352_S	0.505	1.00
394_T	408_T	0.504	1.00
34_E	37_K	0.504	1.00
394_T	401_S	0.504	1.00
153_Q	160_K	0.504	1.00
257_D	261_N	0.503	1.00
106_S	341_G	0.503	1.00
257_D	260_A	0.502	1.00
34_E	351_T	0.502	1.00
92_S	364_K	0.501	1.00
95_A	99_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9258	100	0.261	Contact Map
3giaA	1	0.9528	100	0.321	Contact Map
4djkA	2	0.9079	100	0.346	Contact Map
3dh4A	3	0.9326	98.7	0.863	Contact Map
2jlnA	1	0.9056	98.6	0.867	Contact Map
2xq2A	2	0.9326	98.6	0.868	Contact Map
4wgvA	2	0.8225	97.9	0.891	Contact Map
2a65A	2	0.9461	97.7	0.897	Contact Map
4xp4A	1	0.9528	97	0.908	Contact Map
4us3A	1	0.8764	96.5	0.914	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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