KEFB - ECOLI - GREMLIN Contacts

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KEFB - Glutathione-regulated potassium-efflux system protein KefB

UniProt:	P45522	Sequences: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKVGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG20110
Length:	601 (525)
Sequences:	3711 (2508)
Seq/√Len:	109.5

ECOLI - KEFB KEFC YBAL
BACSU - YJBQ
HALSA - Q9HNK1
SULSO - Q97UN8 Q980D8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
468_I	485_C	7.117	1.00
470_I	482_V	4.063	1.00
310_Y	327_A	4.026	1.00
405_V	416_G	3.849	1.00
184_G	188_L	3.730	1.00
380_L	383_Q	3.577	1.00
298_V	364_L	3.441	1.00
140_M	145_S	3.365	1.00
104_G	108_L	3.297	1.00
402_Q	466_E	3.274	1.00
103_A	120_G	3.271	1.00
310_Y	320_S	3.167	1.00
400_K	464_A	3.046	1.00
376_V	380_L	2.984	1.00
468_I	492_L	2.938	1.00
486_Q	513_T	2.797	1.00
182_K	185_M	2.718	1.00
482_V	512_V	2.708	1.00
486_Q	494_I	2.685	1.00
106_L	116_A	2.622	1.00
295_V	299_V	2.608	1.00
101_L	308_V	2.572	1.00
379_W	383_Q	2.527	1.00
483_E	510_A	2.514	1.00
467_S	530_T	2.506	1.00
376_V	379_W	2.475	1.00
485_C	492_L	2.449	1.00
462_A	468_I	2.406	1.00
195_I	199_Y	2.405	1.00
297_S	361_T	2.399	1.00
470_I	478_T	2.382	1.00
470_I	481_L	2.357	1.00
103_A	107_M	2.350	1.00
341_F	358_L	2.290	1.00
528_R	532_V	2.262	1.00
99_A	121_I	2.257	1.00
351_Q	354_Q	2.203	1.00
404_I	465_A	2.202	1.00
374_K	378_K	2.177	1.00
462_A	489_F	2.177	1.00
401_P	466_E	2.172	1.00
469_V	526_L	2.168	1.00
122_G	341_F	2.135	1.00
258_E	262_A	2.089	1.00
54_D	57_L	2.078	1.00
203_P	207_F	2.074	1.00
301_L	361_T	2.061	1.00
493_H	513_T	2.055	1.00
112_A	115_A	2.040	1.00
15_F	223_L	2.035	1.00
18_V	223_L	2.017	1.00
100_A	104_G	2.005	1.00
458_R	463_E	2.002	1.00
20_A	41_A	1.998	1.00
332_Q	369_T	1.974	1.00
521_S	525_E	1.968	1.00
103_A	113_W	1.945	1.00
469_V	530_T	1.934	1.00
405_V	415_I	1.926	1.00
103_A	117_V	1.920	1.00
337_A	362_V	1.883	1.00
300_V	304_V	1.878	1.00
333_G	337_A	1.876	1.00
202_R	254_E	1.873	1.00
310_Y	314_R	1.858	1.00
148_L	318_V	1.855	1.00
404_I	462_A	1.851	1.00
474_E	477_D	1.845	1.00
345_S	355_M	1.839	1.00
16_A	42_I	1.828	1.00
294_V	357_L	1.819	1.00
283_N	356_A	1.803	1.00
181_M	184_G	1.803	1.00
121_I	163_A	1.774	1.00
333_G	362_V	1.769	1.00
42_I	49_F	1.756	1.00
298_V	365_S	1.748	1.00
472_C	481_L	1.742	1.00
343_T	346_S	1.731	1.00
149_G	329_V	1.717	1.00
130_M	366_M	1.706	1.00
328_G	372_L	1.700	1.00
348_R	352_G	1.680	1.00
357_L	361_T	1.680	1.00
313_A	323_R	1.675	1.00
343_T	347_Q	1.675	1.00
106_L	111_F	1.674	1.00
118_V	344_A	1.660	1.00
210_A	434_S	1.653	1.00
430_E	436_V	1.651	1.00
399_D	402_Q	1.647	1.00
430_E	435_A	1.638	1.00
313_A	318_V	1.624	1.00
498_A	504_A	1.621	1.00
57_L	277_S	1.619	1.00
458_R	488_H	1.614	1.00
406_V	468_I	1.612	1.00
314_R	320_S	1.611	1.00
393_K	396_V	1.604	1.00
301_L	333_G	1.601	1.00
432_D	435_A	1.600	1.00
203_P	206_R	1.598	1.00
292_L	296_I	1.589	1.00
436_V	446_V	1.586	1.00
314_R	317_G	1.584	1.00
152_V	326_F	1.571	1.00
288_Y	291_L	1.570	1.00
493_H	533_T	1.560	1.00
299_V	303_A	1.554	1.00
102_L	106_L	1.551	1.00
92_A	96_L	1.546	1.00
97_L	101_L	1.529	1.00
196_G	200_L	1.526	1.00
506_E	509_Q	1.522	1.00
119_G	358_L	1.522	1.00
68_M	125_M	1.518	1.00
98_S	102_L	1.507	1.00
377_D	380_L	1.495	1.00
302_V	368_T	1.494	1.00
167_V	347_Q	1.485	1.00
411_F	526_L	1.482	1.00
40_I	46_G	1.477	1.00
495_L	533_T	1.470	1.00
512_V	515_F	1.469	1.00
105_L	108_L	1.459	1.00
99_A	163_A	1.458	1.00
439_M	442_Y	1.452	1.00
282_L	363_T	1.448	1.00
145_S	325_Q	1.440	1.00
135_M	146_G	1.433	1.00
482_V	494_I	1.424	1.00
500_G	503_E	1.421	1.00
30_G	133_Q	1.417	1.00
111_F	116_A	1.406	1.00
462_A	488_H	1.406	1.00
90_V	312_L	1.404	1.00
406_V	481_L	1.399	1.00
517_R	520_F	1.379	1.00
41_A	46_G	1.370	1.00
328_G	376_V	1.362	1.00
505_H	509_Q	1.355	1.00
380_L	384_F	1.348	1.00
145_S	322_E	1.346	1.00
98_S	309_L	1.343	1.00
120_G	124_A	1.334	1.00
163_A	340_L	1.314	0.99
52_D	55_E	1.304	0.99
37_L	41_A	1.304	0.99
439_M	444_Y	1.300	0.99
293_W	357_L	1.297	0.99
394_P	397_N	1.297	0.99
392_E	395_W	1.294	0.99
379_W	386_G	1.293	0.99
227_G	231_F	1.288	0.99
29_I	36_L	1.283	0.99
104_G	107_M	1.280	0.99
499_R	518_E	1.277	0.99
254_E	440_R	1.275	0.99
287_L	360_V	1.274	0.99
384_F	387_P	1.274	0.99
95_V	159_A	1.267	0.99
529_K	532_V	1.258	0.99
306_I	328_G	1.257	0.99
479_M	506_E	1.254	0.99
481_L	485_C	1.254	0.99
262_A	453_Q	1.240	0.99
409_G	412_G	1.235	0.99
454_V	488_H	1.228	0.99
90_V	316_Y	1.227	0.99
497_R	518_E	1.224	0.99
12_L	16_A	1.219	0.99
100_A	103_A	1.219	0.99
405_V	469_V	1.213	0.99
293_W	296_I	1.212	0.99
483_E	487_Q	1.212	0.99
91_G	94_Q	1.211	0.99
402_Q	425_R	1.210	0.99
25_S	28_G	1.210	0.99
479_M	510_A	1.209	0.99
199_Y	203_P	1.208	0.99
230_L	234_A	1.207	0.99
138_K	374_K	1.205	0.99
98_S	156_Q	1.202	0.99
95_V	155_F	1.201	0.99
501_R	517_R	1.194	0.99
412_G	471_T	1.194	0.99
525_E	529_K	1.189	0.99
258_E	261_T	1.183	0.99
495_L	526_L	1.182	0.99
104_G	113_W	1.178	0.99
126_S	156_Q	1.173	0.99
319_R	323_R	1.167	0.99
514_Q	529_K	1.167	0.99
381_S	385_N	1.166	0.99
180_W	183_V	1.164	0.99
160_V	340_L	1.161	0.99
250_L	259_L	1.160	0.99
298_V	302_V	1.158	0.99
408_F	416_G	1.153	0.99
451_A	481_L	1.153	0.99
479_M	483_E	1.152	0.99
495_L	530_T	1.149	0.99
489_F	492_L	1.146	0.99
81_W	84_R	1.145	0.99
418_L	527_G	1.144	0.99
88_F	92_A	1.138	0.98
11_V	230_L	1.136	0.98
202_R	253_S	1.133	0.98
347_Q	352_G	1.127	0.98
46_G	49_F	1.110	0.98
107_M	113_W	1.104	0.98
152_V	330_L	1.104	0.98
140_M	373_M	1.101	0.98
404_I	468_I	1.098	0.98
384_F	388_E	1.094	0.98
101_L	304_V	1.093	0.98
406_V	451_A	1.089	0.98
125_M	163_A	1.087	0.98
153_L	336_F	1.084	0.98
403_V	469_V	1.082	0.98
119_G	123_L	1.082	0.98
131_A	330_L	1.078	0.98
86_S	151_S	1.072	0.98
485_C	489_F	1.071	0.98
388_E	391_D	1.070	0.98
379_W	382_R	1.069	0.98
473_N	518_E	1.067	0.98
301_L	365_S	1.064	0.98
472_C	478_T	1.059	0.98
334_G	338_F	1.058	0.98
393_K	397_N	1.058	0.98
529_K	533_T	1.058	0.98
76_N	252_E	1.056	0.97
461_G	464_A	1.056	0.97
433_I	437_N	1.055	0.97
118_V	122_G	1.048	0.97
13_F	21_V	1.047	0.97
98_S	308_V	1.044	0.97
513_T	533_T	1.044	0.97
15_F	19_A	1.044	0.97
439_M	446_V	1.040	0.97
410_R	497_R	1.036	0.97
115_A	351_Q	1.030	0.97
378_K	382_R	1.030	0.97
101_L	104_G	1.030	0.97
229_A	239_M	1.029	0.97
96_L	99_A	1.027	0.97
209_A	255_Y	1.024	0.97
462_A	492_L	1.023	0.97
311_L	315_L	1.020	0.97
42_I	280_M	1.017	0.97
188_L	192_G	1.014	0.97
403_V	419_L	1.012	0.97
416_G	426_I	1.012	0.97
436_V	448_Y	1.007	0.97
475_P	478_T	1.006	0.97
477_D	480_K	1.000	0.97
87_I	106_L	0.998	0.96
96_L	100_A	0.997	0.96
290_H	353_D	0.995	0.96
364_L	368_T	0.993	0.96
73_L	248_V	0.989	0.96
435_A	438_L	0.987	0.96
290_H	293_W	0.986	0.96
493_H	514_Q	0.986	0.96
95_V	98_S	0.985	0.96
277_S	281_S	0.984	0.96
397_N	400_K	0.978	0.96
78_S	82_Q	0.978	0.96
435_A	439_M	0.977	0.96
305_K	330_L	0.975	0.96
516_S	525_E	0.973	0.96
496_A	510_A	0.970	0.96
8_L	11_V	0.970	0.96
420_M	426_I	0.969	0.96
126_S	330_L	0.967	0.96
368_T	372_L	0.956	0.95
384_F	391_D	0.953	0.95
379_W	387_P	0.947	0.95
380_L	386_G	0.946	0.95
129_A	160_V	0.946	0.95
205_F	224_L	0.942	0.95
111_F	119_G	0.941	0.95
387_P	391_D	0.940	0.95
391_D	394_P	0.939	0.95
103_A	106_L	0.936	0.95
412_G	430_E	0.934	0.95
503_E	507_L	0.933	0.95
479_M	503_E	0.933	0.95
314_R	323_R	0.932	0.95
243_T	323_R	0.928	0.95
366_M	369_T	0.927	0.95
128_T	335_E	0.922	0.95
521_S	526_L	0.918	0.94
475_P	506_E	0.917	0.94
428_V	444_Y	0.913	0.94
335_E	338_F	0.907	0.94
127_S	274_F	0.906	0.94
377_D	387_P	0.906	0.94
21_V	31_A	0.904	0.94
156_Q	335_E	0.904	0.94
504_A	515_F	0.903	0.94
526_L	530_T	0.902	0.94
83_L	86_S	0.902	0.94
35_Y	43_G	0.901	0.94
75_L	251_A	0.900	0.94
201_L	224_L	0.899	0.94
527_G	531_L	0.897	0.94
200_L	203_P	0.897	0.94
391_D	395_W	0.896	0.94
196_G	199_Y	0.895	0.94
312_L	316_Y	0.895	0.94
27_L	452_T	0.894	0.94
189_A	193_M	0.893	0.94
83_L	87_I	0.892	0.93
37_L	54_D	0.886	0.93
519_T	523_A	0.885	0.93
302_V	331_S	0.884	0.93
525_E	532_V	0.882	0.93
156_Q	336_F	0.882	0.93
229_A	232_M	0.881	0.93
396_V	399_D	0.880	0.93
408_F	444_Y	0.880	0.93
380_L	387_P	0.880	0.93
516_S	526_L	0.878	0.93
153_L	156_Q	0.878	0.93
175_D	178_F	0.874	0.93
321_S	325_Q	0.873	0.93
94_Q	98_S	0.873	0.93
102_L	304_V	0.872	0.93
228_S	249_L	0.871	0.93
208_I	220_A	0.868	0.93
191_V	195_I	0.862	0.92
92_A	155_F	0.862	0.92
426_I	445_K	0.860	0.92
105_L	304_V	0.860	0.92
375_L	378_K	0.859	0.92
208_I	217_F	0.859	0.92
512_V	517_R	0.858	0.92
403_V	530_T	0.857	0.92
494_I	512_V	0.856	0.92
84_R	524_L	0.852	0.92
51_S	56_I	0.851	0.92
499_R	517_R	0.851	0.92
193_M	249_L	0.851	0.92
11_V	226_L	0.849	0.92
149_G	278_V	0.848	0.92
108_L	171_A	0.847	0.92
106_L	354_Q	0.846	0.92
514_Q	533_T	0.846	0.92
156_Q	160_V	0.845	0.92
90_V	306_I	0.843	0.91
112_A	116_A	0.842	0.91
88_F	94_Q	0.840	0.91
35_Y	272_G	0.840	0.91
131_A	153_L	0.839	0.91
341_F	350_F	0.837	0.91
125_M	160_V	0.836	0.91
518_E	523_A	0.834	0.91
470_I	496_A	0.831	0.91
93_A	97_L	0.829	0.91
375_L	379_W	0.829	0.91
48_G	60_S	0.829	0.91
382_R	387_P	0.828	0.91
74_E	129_A	0.826	0.91
408_F	428_V	0.826	0.91
21_V	272_G	0.825	0.91
44_P	449_G	0.825	0.91
382_R	388_E	0.824	0.90
17_A	53_V	0.824	0.90
264_D	268_G	0.824	0.90
131_A	329_V	0.823	0.90
221_T	259_L	0.823	0.90
216_V	523_A	0.820	0.90
103_A	177_H	0.820	0.90
219_A	270_L	0.819	0.90
379_W	384_F	0.818	0.90
510_A	513_T	0.818	0.90
454_V	487_Q	0.817	0.90
482_V	496_A	0.817	0.90
412_G	436_V	0.815	0.90
345_S	352_G	0.815	0.90
192_G	195_I	0.813	0.90
480_K	483_E	0.813	0.90
256_R	270_L	0.811	0.90
382_R	386_G	0.811	0.90
186_K	190_F	0.809	0.90
344_A	348_R	0.809	0.90
379_W	388_E	0.808	0.90
478_T	510_A	0.806	0.89
521_S	524_L	0.805	0.89
88_F	91_G	0.802	0.89
24_A	37_L	0.802	0.89
131_A	193_M	0.801	0.89
350_F	354_Q	0.800	0.89
454_V	484_I	0.800	0.89
402_Q	465_A	0.798	0.89
438_L	442_Y	0.797	0.89
156_Q	274_F	0.797	0.89
498_A	502_V	0.797	0.89
303_A	306_I	0.796	0.89
429_L	447_Y	0.795	0.89
329_V	373_M	0.795	0.89
31_A	327_A	0.789	0.88
27_L	256_R	0.788	0.88
71_I	75_L	0.788	0.88
318_V	322_E	0.787	0.88
516_S	529_K	0.787	0.88
12_L	49_F	0.784	0.88
342_S	346_S	0.778	0.88
82_Q	85_R	0.776	0.88
394_P	474_E	0.776	0.88
411_F	471_T	0.774	0.88
88_F	249_L	0.774	0.88
468_I	481_L	0.769	0.87
33_L	367_M	0.766	0.87
66_F	80_L	0.765	0.87
334_G	339_V	0.765	0.87
87_I	94_Q	0.764	0.87
382_R	385_N	0.764	0.87
219_A	268_G	0.762	0.87
63_G	242_G	0.758	0.86
140_M	325_Q	0.757	0.86
219_A	269_L	0.756	0.86
123_L	410_R	0.755	0.86
427_T	462_A	0.755	0.86
496_A	507_L	0.755	0.86
309_L	312_L	0.755	0.86
466_E	493_H	0.754	0.86
410_R	473_N	0.754	0.86
24_A	34_G	0.752	0.86
302_V	372_L	0.751	0.86
290_H	357_L	0.750	0.86
75_L	280_M	0.750	0.86
374_K	377_D	0.749	0.86
94_Q	336_F	0.748	0.86
44_P	280_M	0.747	0.86
176_E	179_D	0.746	0.86
403_V	424_M	0.738	0.85
122_G	350_F	0.738	0.85
221_T	276_I	0.738	0.85
86_S	148_L	0.737	0.85
527_G	533_T	0.737	0.85
40_I	182_K	0.737	0.85
475_P	503_E	0.736	0.85
416_G	428_V	0.736	0.85
515_F	526_L	0.736	0.85
206_R	254_E	0.735	0.85
217_F	221_T	0.734	0.85
413_Q	442_Y	0.733	0.85
437_N	440_R	0.730	0.84
20_A	183_V	0.729	0.84
188_L	191_V	0.728	0.84
96_L	368_T	0.728	0.84
123_L	301_L	0.727	0.84
174_A	188_L	0.726	0.84
335_E	339_V	0.725	0.84
362_V	365_S	0.724	0.84
43_G	50_I	0.722	0.84
220_A	224_L	0.718	0.83
38_A	253_S	0.718	0.83
283_N	286_V	0.717	0.83
238_S	241_L	0.716	0.83
123_L	358_L	0.714	0.83
65_V	68_M	0.714	0.83
381_S	386_G	0.714	0.83
280_M	306_I	0.713	0.83
320_S	327_A	0.712	0.83
152_V	309_L	0.711	0.83
367_M	371_L	0.710	0.83
433_I	436_V	0.710	0.83
410_R	499_R	0.709	0.83
383_Q	386_G	0.707	0.82
355_M	359_L	0.706	0.82
18_V	21_V	0.706	0.82
113_W	116_A	0.704	0.82
467_S	493_H	0.704	0.82
469_V	495_L	0.704	0.82
517_R	523_A	0.703	0.82
15_F	227_G	0.702	0.82
184_G	187_V	0.702	0.82
354_Q	357_L	0.702	0.82
362_V	366_M	0.701	0.82
128_T	153_L	0.701	0.82
377_D	384_F	0.699	0.82
493_H	496_A	0.699	0.82
392_E	397_N	0.697	0.81
516_S	522_S	0.696	0.81
192_G	235_L	0.695	0.81
217_F	220_A	0.695	0.81
156_Q	330_L	0.694	0.81
130_M	373_M	0.694	0.81
20_A	38_A	0.693	0.81
403_V	467_S	0.692	0.81
126_S	308_V	0.691	0.81
106_L	119_G	0.691	0.81
523_A	530_T	0.691	0.81
285_G	289_T	0.691	0.81
454_V	489_F	0.691	0.81
215_E	219_A	0.690	0.81
8_L	131_A	0.690	0.81
404_I	492_L	0.689	0.81
95_V	124_A	0.689	0.81
345_S	350_F	0.688	0.81
133_Q	268_G	0.687	0.81
11_V	223_L	0.685	0.80
510_A	516_S	0.685	0.80
414_V	520_F	0.681	0.80
358_L	363_T	0.681	0.80
122_G	163_A	0.680	0.80
23_L	470_I	0.680	0.80
309_L	326_F	0.679	0.80
486_Q	512_V	0.679	0.80
30_G	122_G	0.678	0.80
297_S	357_L	0.678	0.80
111_F	297_S	0.676	0.79
201_L	205_F	0.675	0.79
512_V	526_L	0.674	0.79
400_K	466_E	0.674	0.79
97_L	312_L	0.674	0.79
206_R	210_A	0.673	0.79
321_S	379_W	0.672	0.79
179_D	463_E	0.671	0.79
221_T	302_V	0.671	0.79
517_R	521_S	0.668	0.79
395_W	400_K	0.668	0.79
415_I	469_V	0.668	0.79
378_K	403_V	0.667	0.79
87_I	155_F	0.665	0.78
218_T	241_L	0.663	0.78
520_F	524_L	0.662	0.78
161_I	339_V	0.662	0.78
405_V	523_A	0.661	0.78
525_E	528_R	0.660	0.78
128_T	336_F	0.659	0.78
468_I	490_P	0.658	0.78
416_G	425_R	0.657	0.77
187_V	191_V	0.656	0.77
188_L	289_T	0.654	0.77
19_A	23_L	0.653	0.77
165_A	343_T	0.652	0.77
66_F	164_L	0.651	0.77
410_R	500_G	0.651	0.77
126_S	129_A	0.650	0.77
367_M	370_P	0.647	0.76
495_L	514_Q	0.647	0.76
327_A	376_V	0.646	0.76
71_I	128_T	0.645	0.76
105_L	115_A	0.645	0.76
523_A	527_G	0.645	0.76
300_V	303_A	0.644	0.76
156_Q	308_V	0.644	0.76
14_L	223_L	0.643	0.76
361_T	369_T	0.643	0.76
501_R	504_A	0.642	0.76
75_L	281_S	0.640	0.76
429_L	460_A	0.640	0.76
455_D	528_R	0.639	0.76
43_G	46_G	0.638	0.75
118_V	167_V	0.638	0.75
296_I	300_V	0.638	0.75
306_I	331_S	0.637	0.75
129_A	272_G	0.637	0.75
381_S	509_Q	0.636	0.75
104_G	476_E	0.635	0.75
221_T	251_A	0.632	0.75
437_N	441_K	0.631	0.75
95_V	163_A	0.631	0.75
456_L	460_A	0.630	0.75
322_E	326_F	0.630	0.75
381_S	391_D	0.630	0.75
109_T	297_S	0.627	0.74
334_G	337_A	0.627	0.74
163_A	287_L	0.626	0.74
90_V	94_Q	0.624	0.74
89_G	316_Y	0.623	0.74
406_V	472_C	0.622	0.74
32_V	125_M	0.621	0.73
119_G	301_L	0.621	0.73
174_A	295_V	0.620	0.73
131_A	300_V	0.619	0.73
293_W	510_A	0.618	0.73
130_M	428_V	0.617	0.73
85_R	288_Y	0.616	0.73
106_L	297_S	0.616	0.73
106_L	120_G	0.616	0.73
72_G	279_G	0.616	0.73
98_S	101_L	0.615	0.73
411_F	497_R	0.615	0.73
174_A	179_D	0.614	0.73
486_Q	491_H	0.614	0.73
239_M	273_L	0.613	0.72
135_M	149_G	0.613	0.72
75_L	258_E	0.613	0.72
470_I	512_V	0.612	0.72
125_M	129_A	0.612	0.72
164_L	263_I	0.612	0.72
282_L	360_V	0.611	0.72
416_G	439_M	0.609	0.72
504_A	508_L	0.607	0.72
295_V	298_V	0.607	0.72
504_A	516_S	0.607	0.72
188_L	294_V	0.606	0.72
166_L	287_L	0.606	0.72
135_M	270_L	0.605	0.72
352_G	400_K	0.605	0.72
152_V	160_V	0.604	0.71
409_G	471_T	0.604	0.71
133_Q	137_E	0.604	0.71
75_L	123_L	0.603	0.71
362_V	369_T	0.603	0.71
34_G	72_G	0.603	0.71
161_I	240_A	0.601	0.71
497_R	519_T	0.601	0.71
131_A	332_Q	0.601	0.71
105_L	297_S	0.600	0.71
145_S	326_F	0.600	0.71
162_P	236_G	0.599	0.71
153_L	335_E	0.598	0.71
410_R	413_Q	0.597	0.71
267_K	271_L	0.596	0.70
190_F	194_L	0.595	0.70
242_G	274_F	0.594	0.70
102_L	301_L	0.593	0.70
391_D	397_N	0.593	0.70
92_A	95_V	0.592	0.70
18_V	220_A	0.592	0.70
292_L	295_V	0.592	0.70
126_S	335_E	0.591	0.70
293_W	297_S	0.590	0.70
289_T	292_L	0.589	0.70
217_F	255_Y	0.589	0.70
71_I	357_L	0.588	0.69
63_G	67_L	0.588	0.69
222_L	269_L	0.587	0.69
113_W	117_V	0.587	0.69
8_L	95_V	0.586	0.69
282_L	309_L	0.585	0.69
383_Q	388_E	0.585	0.69
317_G	320_S	0.584	0.69
187_V	195_I	0.584	0.69
80_L	294_V	0.584	0.69
294_V	298_V	0.583	0.69
432_D	446_V	0.582	0.69
134_L	316_Y	0.582	0.69
60_S	63_G	0.582	0.69
31_A	87_I	0.581	0.68
471_T	520_F	0.581	0.68
380_L	388_E	0.581	0.68
207_F	211_S	0.579	0.68
121_I	166_L	0.579	0.68
524_L	531_L	0.579	0.68
109_T	293_W	0.579	0.68
253_S	259_L	0.579	0.68
33_L	344_A	0.578	0.68
429_L	456_L	0.576	0.68
198_R	249_L	0.576	0.68
59_F	418_L	0.574	0.68
410_R	519_T	0.574	0.68
14_L	254_E	0.573	0.67
417_R	442_Y	0.572	0.67
99_A	103_A	0.571	0.67
392_E	399_D	0.571	0.67
392_E	396_V	0.570	0.67
394_P	399_D	0.569	0.67
122_G	340_L	0.568	0.67
434_S	438_L	0.568	0.67
75_L	132_L	0.567	0.67
301_L	327_A	0.567	0.67
63_G	66_F	0.566	0.66
289_T	311_L	0.564	0.66
93_A	316_Y	0.564	0.66
350_F	355_M	0.564	0.66
454_V	458_R	0.564	0.66
289_T	353_D	0.563	0.66
172_G	175_D	0.563	0.66
197_G	228_S	0.562	0.66
451_A	472_C	0.560	0.66
380_L	385_N	0.560	0.66
95_V	241_L	0.559	0.66
331_S	372_L	0.559	0.66
94_Q	153_L	0.557	0.65
386_G	391_D	0.556	0.65
175_D	351_Q	0.555	0.65
311_L	328_G	0.555	0.65
518_E	522_S	0.555	0.65
323_R	327_A	0.554	0.65
209_A	217_F	0.553	0.65
116_A	351_Q	0.552	0.65
178_F	319_R	0.552	0.65
244_F	305_K	0.550	0.64
291_L	294_V	0.549	0.64
85_R	88_F	0.549	0.64
67_L	126_S	0.549	0.64
115_A	354_Q	0.548	0.64
190_F	245_I	0.548	0.64
429_L	449_G	0.548	0.64
60_S	277_S	0.547	0.64
67_L	326_F	0.547	0.64
104_G	117_V	0.546	0.64
395_W	398_D	0.546	0.64
368_T	509_Q	0.545	0.64
348_R	351_Q	0.545	0.64
320_S	388_E	0.545	0.64
294_V	327_A	0.544	0.63
11_V	18_V	0.544	0.63
319_R	322_E	0.543	0.63
37_L	479_M	0.543	0.63
438_L	441_K	0.541	0.63
36_L	42_I	0.539	0.63
496_A	512_V	0.539	0.63
160_V	167_V	0.539	0.63
516_S	519_T	0.539	0.63
126_S	131_A	0.538	0.63
205_F	220_A	0.538	0.63
484_I	487_Q	0.538	0.63
330_L	336_F	0.537	0.62
400_K	425_R	0.537	0.62
504_A	525_E	0.537	0.62
391_D	396_V	0.537	0.62
353_D	458_R	0.537	0.62
235_L	440_R	0.536	0.62
134_L	189_A	0.536	0.62
67_L	128_T	0.535	0.62
329_V	332_Q	0.534	0.62
65_V	239_M	0.533	0.62
138_K	251_A	0.533	0.62
127_S	332_Q	0.532	0.62
129_A	153_L	0.532	0.62
116_A	327_A	0.532	0.62
224_L	228_S	0.531	0.62
90_V	98_S	0.531	0.62
520_F	523_A	0.530	0.61
77_P	81_W	0.530	0.61
524_L	529_K	0.530	0.61
474_E	479_M	0.529	0.61
123_L	333_G	0.528	0.61
37_L	379_W	0.527	0.61
63_G	274_F	0.525	0.61
286_V	290_H	0.525	0.61
260_E	272_G	0.525	0.61
430_E	446_V	0.524	0.61
269_L	340_L	0.523	0.60
91_G	95_V	0.523	0.60
274_F	335_E	0.522	0.60
516_S	520_F	0.522	0.60
374_K	484_I	0.521	0.60
379_W	385_N	0.520	0.60
108_L	319_R	0.520	0.60
516_S	528_R	0.519	0.60
114_Q	117_V	0.519	0.60
524_L	528_R	0.518	0.60
505_H	508_L	0.517	0.60
233_D	259_L	0.517	0.60
70_I	216_V	0.515	0.59
174_A	178_F	0.515	0.59
494_I	513_T	0.515	0.59
501_R	505_H	0.515	0.59
418_L	520_F	0.515	0.59
172_G	180_W	0.514	0.59
154_L	273_L	0.514	0.59
136_R	141_N	0.512	0.59
12_L	42_I	0.512	0.59
291_L	341_F	0.512	0.59
383_Q	391_D	0.511	0.59
24_A	33_L	0.511	0.59
332_Q	340_L	0.511	0.59
96_L	296_I	0.508	0.58
486_Q	489_F	0.508	0.58
60_S	226_L	0.508	0.58
71_I	125_M	0.508	0.58
302_V	529_K	0.507	0.58
132_L	141_N	0.507	0.58
102_L	123_L	0.507	0.58
110_D	113_W	0.506	0.58
63_G	244_F	0.506	0.58
127_S	335_E	0.505	0.58
485_C	490_P	0.505	0.58
463_E	491_H	0.505	0.58
448_Y	498_A	0.504	0.58
190_F	428_V	0.504	0.58
447_Y	456_L	0.503	0.57
134_L	329_V	0.503	0.57
352_G	355_M	0.502	0.57
128_T	156_Q	0.501	0.57
352_G	356_A	0.501	0.57
234_A	459_S	0.500	0.57
178_F	287_L	0.500	0.57

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4bwzA	2	0.6306	100	0.57	Contact Map
4czbA	2	0.6339	100	0.612	Contact Map
4cz8A	2	0.6273	100	0.619	Contact Map
3l9wA	2	0.3012	100	0.771	Contact Map
1zcdA	1	0.5657	100	0.805	Contact Map
4gx0A	3	0.4975	99.9	0.812	Contact Map
1lnqA	6	0.4542	99.9	0.821	Contact Map
2aefA	2	0.3295	99.9	0.837	Contact Map
3c85A	2	0.2479	99.9	0.843	Contact Map
3nafA	3	0.3478	99.9	0.843	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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