GREMLIN Database
YRAR - Uncharacterized protein YraR
UniProt: P45469 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12783
Length: 211 (192)
Sequences: 48950 (33678)
Seq/√Len: 2430.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
9_A32_A3.3831.00
3_Q29_A2.9581.00
20_M184_R2.6101.00
57_A100_R2.4621.00
85_H89_T2.3941.00
33_P50_P2.2041.00
65_I190_S2.2001.00
109_V186_M2.1321.00
31_A63_I2.0751.00
105_H140_K2.0451.00
20_M24_E1.9811.00
5_L63_I1.9741.00
146_P186_M1.9721.00
79_S82_A1.9551.00
6_I18_L1.9351.00
68_C108_V1.9221.00
31_A46_N1.9141.00
67_F190_S1.8601.00
7_T68_C1.8391.00
3_Q31_A1.8341.00
24_E191_M1.8271.00
29_A46_N1.7741.00
20_M187_L1.7641.00
133_L141_L1.7391.00
53_S85_H1.7371.00
184_R188_A1.7251.00
31_A48_H1.6891.00
144_A189_E1.6841.00
17_L183_A1.6611.00
95_A136_Q1.6471.00
110_S114_A1.6291.00
92_V96_L1.5491.00
69_C109_V1.5471.00
17_L67_F1.5391.00
92_V132_A1.5371.00
64_D104_Q1.5051.00
57_A97_T1.5041.00
17_L69_C1.5001.00
13_V149_L1.4971.00
91_V129_M1.4901.00
89_T92_V1.4811.00
36_R47_P1.4571.00
10_T34_T1.4481.00
127_G131_E1.4331.00
84_I128_E1.4091.00
20_M23_N1.4051.00
157_R160_E1.3951.00
18_L32_A1.3841.00
57_A101_L1.3831.00
105_H142_T1.3811.00
87_D125_V1.3791.00
19_R153_R1.3341.00
144_A186_M1.3081.00
137_N141_L1.3001.00
20_M183_A1.2961.00
98_G106_M1.2951.00
52_L90_L1.2921.00
67_F186_M1.2881.00
68_C91_V1.2781.00
94_T106_M1.2671.00
24_E187_L1.2671.00
150_L178_D1.2631.00
187_L191_M1.2591.00
158_M162_L1.2591.00
4_V28_N1.2481.00
122_Y126_K1.2451.00
66_V98_G1.2431.00
188_A192_R1.2391.00
109_V146_P1.2281.00
28_N191_M1.2271.00
131_E134_I1.2251.00
165_P170_L1.2251.00
107_L144_A1.2071.00
81_E85_H1.2051.00
24_E28_N1.1991.00
61_D101_L1.1951.00
9_A18_L1.1871.00
177_I182_V1.1851.00
130_E145_R1.1751.00
4_V21_L1.1721.00
5_L33_P1.1711.00
4_V65_I1.1671.00
108_V129_M1.1531.00
16_H180_R1.1511.00
32_A45_F1.1501.00
69_C186_M1.1451.00
7_T94_T1.1341.00
22_I45_F1.1301.00
179_A183_A1.1171.00
160_E163_F1.1171.00
98_G103_A1.1081.00
96_L99_R1.1031.00
58_Q61_D1.0981.00
146_P182_V1.0931.00
95_A106_M1.0931.00
134_I143_I1.0911.00
52_L70_L1.0881.00
20_M180_R1.0811.00
108_V133_L1.0801.00
56_L97_T1.0691.00
19_R23_N1.0671.00
60_T66_V1.0621.00
55_A96_L1.0541.00
124_R128_E1.0491.00
156_Q160_E1.0481.00
160_E164_A1.0311.00
25_P28_N1.0291.00
66_V94_T1.0281.00
86_A90_L1.0181.00
178_D181_D1.0181.00
160_E166_L0.9981.00
89_T93_D0.9951.00
31_A62_P0.9941.00
36_R39_G0.9891.00
96_L100_R0.9851.00
161_T165_P0.9811.00
164_A168_R0.9701.00
95_A132_A0.9671.00
106_M133_L0.9651.00
17_L21_L0.9621.00
33_P56_L0.9601.00
21_L187_L0.9601.00
149_L182_V0.9591.00
3_Q28_N0.9571.00
108_V143_I0.9501.00
57_A61_D0.9451.00
22_I44_V0.9411.00
60_T63_I0.9381.00
112_M147_S0.9291.00
110_S130_E0.9261.00
72_T86_A0.9241.00
132_A135_A0.9221.00
3_Q63_I0.9191.00
4_V67_F0.9191.00
157_R161_T0.9141.00
88_Y128_E0.9131.00
34_T47_P0.9101.00
95_A133_L0.9011.00
12_L179_A0.8991.00
96_L136_Q0.8961.00
97_T101_L0.8961.00
84_I89_T0.8941.00
83_F125_V0.8911.00
99_R139_P0.8911.00
93_D96_L0.8831.00
166_L169_L0.8791.00
166_L170_L0.8731.00
60_T101_L0.8711.00
142_T189_E0.8701.00
60_T97_T0.8631.00
35_R51_Q0.8561.00
15_G153_R0.8471.00
33_P59_V0.8411.00
16_H179_A0.8401.00
159_N163_F0.8401.00
99_R136_Q0.8361.00
12_L151_G0.8241.00
163_F166_L0.8141.00
168_R171_P0.8071.00
7_T70_L0.8061.00
3_Q64_D0.8031.00
42_P45_F0.8021.00
37_P49_D0.8011.00
134_I141_L0.7971.00
147_S175_K0.7971.00
60_T98_G0.7901.00
22_I30_I0.7871.00
84_I88_Y0.7871.00
16_H20_M0.7841.00
36_R49_D0.7791.00
144_A185_V0.7741.00
97_T100_R0.7731.00
18_L30_I0.7701.00
152_D178_D0.7681.00
193_P196_E0.7621.00
188_A191_M0.7611.00
25_P44_V0.7611.00
72_T83_F0.7521.00
162_L165_P0.7461.00
48_H59_V0.7451.00
56_L93_D0.7371.00
55_A93_D0.7321.00
184_R187_L0.7321.00
91_V133_L0.7241.00
129_M133_L0.7201.00
4_V190_S0.7201.00
104_Q140_K0.7201.00
131_E135_A0.7181.00
156_Q159_N0.7171.00
28_N64_D0.7161.00
135_A139_P0.7161.00
17_L186_M0.7081.00
66_V106_M0.7071.00
162_L166_L0.7061.00
134_I138_W0.7051.00
157_R162_L0.7021.00
165_P169_L0.7011.00
16_H19_R0.6961.00
82_A85_H0.6961.00
142_T193_P0.6961.00
124_R135_A0.6921.00
120_F123_N0.6911.00
5_L60_T0.6881.00
10_T36_R0.6871.00
105_H193_P0.6871.00
113_G123_N0.6861.00
84_I124_R0.6791.00
161_T164_A0.6761.00
160_E165_P0.6721.00
5_L50_P0.6701.00
167_F170_L0.6661.00
16_H183_A0.6651.00
159_N162_L0.6651.00
115_N145_R0.6651.00
36_R41_M0.6631.00
146_P149_L0.6581.00
156_Q161_T0.6551.00
114_A145_R0.6521.00
162_L169_L0.6461.00
13_V182_V0.6461.00
149_L177_I0.6451.00
72_T87_D0.6381.00
53_S86_A0.6331.00
65_I105_H0.6331.00
21_L190_S0.6331.00
84_I125_V0.6291.00
69_C146_P0.6291.00
160_E170_L0.6281.00
160_E168_R0.6271.00
29_A44_V0.6231.00
128_E131_E0.6221.00
183_A187_L0.6171.00
161_T166_L0.6151.00
59_V63_I0.6131.00
3_Q62_P0.6091.00
158_M161_T0.6081.00
132_A136_Q0.6081.00
90_L93_D0.6021.00
124_R131_E0.6011.00
148_M176_S0.5971.00
128_E132_A0.5961.00
32_A47_P0.5941.00
114_A130_E0.5911.00
135_A138_W0.5911.00
157_R169_L0.5891.00
24_E188_A0.5871.00
72_T82_A0.5871.00
163_F167_F0.5831.00
24_E184_R0.5821.00
92_V136_Q0.5781.00
165_P168_R0.5781.00
96_L132_A0.5761.00
5_L66_V0.5731.00
60_T94_T0.5721.00
93_D97_T0.5701.00
19_R180_R0.5661.00
157_R163_F0.5631.00
107_L189_E0.5621.00
55_A100_R0.5601.00
54_D57_A0.5531.00
80_K124_R0.5531.00
91_V95_A0.5511.00
111_A114_A0.5461.00
41_M49_D0.5451.00
22_I42_P0.5431.00
110_S143_I0.5421.00
134_I137_N0.5411.00
158_M163_F0.5381.00
31_A59_V0.5361.00
177_I181_D0.5351.00
114_A127_G0.5341.00
181_D184_R0.5341.00
16_H153_R0.5321.00
71_G87_D0.5231.00
21_L25_P0.5211.00
6_I21_L0.5211.00
163_F170_L0.5191.00
65_I104_Q0.5181.00
107_L190_S0.5151.00
28_N65_I0.5141.00
65_I107_L0.5141.00
140_K195_H0.5121.00
121_F125_V0.5061.00
160_E169_L0.5051.00
88_Y125_V0.5041.00
133_L143_I0.5041.00
66_V103_A0.5001.00
5_L59_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2x4gA 2 0.9242 100 0.248 Contact Map
2pzmA 2 0.981 100 0.256 Contact Map
2q1wA 2 0.9763 100 0.259 Contact Map
3m2pA 2 0.9621 100 0.26 Contact Map
1sb8A 2 0.9905 100 0.263 Contact Map
3rufA 2 0.9905 100 0.268 Contact Map
4wkgA 5 0.9858 100 0.268 Contact Map
1rkxA 3 0.9905 100 0.269 Contact Map
2q1sA 2 0.9573 100 0.271 Contact Map
1orrA 3 0.9858 100 0.271 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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