GREMLIN Database
YRAI - Probable fimbrial chaperone YraI
UniProt: P42914 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12774
Length: 231 (213)
Sequences: 2873 (2169)
Seq/√Len: 148.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
61_V137_M3.2651.00
175_V192_Y3.1751.00
173_Y194_A2.9721.00
36_D39_R2.8961.00
194_A197_E2.8841.00
167_Y198_H2.8771.00
102_K196_G2.8601.00
105_L192_Y2.8411.00
28_L135_I2.7871.00
98_L106_F2.7271.00
55_Y112_A2.5331.00
33_V42_A2.5281.00
157_F166_I2.5171.00
165_N200_Q2.4981.00
165_N198_H2.4851.00
33_V108_I2.4431.00
156_E167_Y2.4391.00
138_F192_Y2.4101.00
38_S142_A2.3561.00
33_V91_I2.3181.00
150_D153_K2.2721.00
166_I201_L2.1731.00
217_N223_S2.1531.00
54_P82_E2.1181.00
138_F173_Y2.1151.00
163_S200_Q2.0701.00
60_W109_N2.0271.00
62_D134_R2.0221.00
158_K165_N1.9631.00
111_R132_K1.8591.00
36_D42_A1.8421.00
59_S89_L1.8301.00
54_P80_R1.7721.00
144_L172_Y1.7481.00
99_P104_S1.7471.00
151_A174_V1.7401.00
62_D109_N1.6781.00
74_I89_L1.6441.00
72_F91_I1.6341.00
28_L110_V1.6011.00
61_V70_A1.5971.00
109_N134_R1.5751.00
82_E85_D1.5531.00
155_L166_I1.5211.00
105_L138_F1.5201.00
174_V215_A1.5161.00
217_N221_G1.4921.00
154_S170_T1.4901.00
44_L108_I1.4811.00
160_S163_S1.4811.00
151_A215_A1.4731.00
93_K96_D1.4621.00
155_L176_F1.4571.00
178_G214_A1.4511.00
37_A100_E1.4461.00
99_P102_K1.4441.00
160_S165_N1.4291.00
147_R150_D1.4101.00
57_L79_F1.3881.00
72_F137_M1.3751.00
157_F213_W1.3531.00
35_Y42_A1.3331.00
74_I91_I1.3201.00
155_L174_V1.3091.00
45_P86_D1.3041.00
193_I199_K1.2971.00
148_V151_A1.2891.00
105_L175_V1.2751.00
163_S202_P1.2661.00
158_K167_Y1.2541.00
41_E90_R1.2521.00
180_A212_K1.2391.00
171_E196_G1.2291.00
50_G112_A1.2221.00
33_V135_I1.2181.00
63_N67_K1.2131.00
159_R162_H1.2091.00
52_E84_G1.2071.00
46_V81_L1.1891.00
175_V215_A1.1821.00
8_V16_F1.1811.00
37_A142_A1.1601.00
152_W174_V1.1581.00
28_L44_L1.1581.00
117_K126_E1.1541.00
65_D68_S1.1511.00
177_A222_S1.1471.00
62_D66_G1.1461.00
93_K97_N1.1411.00
215_A223_S1.1361.00
60_W134_R1.1351.00
176_F193_I1.1351.00
91_I137_M1.1270.99
93_K139_Y1.1210.99
108_I137_M1.0980.99
154_S169_P1.0730.99
164_L203_L1.0660.99
180_A185_D1.0550.99
27_V30_R1.0460.99
117_K128_T1.0370.99
79_F87_S1.0300.99
112_A131_F1.0200.99
35_Y92_I1.0180.99
25_G112_A1.0160.99
107_Y134_R1.0160.99
37_A139_Y1.0040.99
89_L108_I0.9970.99
60_W111_R0.9940.99
26_I81_L0.9910.99
30_R44_L0.9810.99
29_Q45_P0.9770.98
146_G172_Y0.9640.98
87_S111_R0.9580.98
12_L15_S0.9560.98
50_G55_Y0.9540.98
47_A86_D0.9480.98
74_I108_I0.9470.98
89_L110_V0.9310.98
26_I57_L0.9210.98
184_T206_S0.9160.98
156_E169_P0.9140.98
176_F215_A0.9140.98
28_L46_V0.9120.98
62_D107_Y0.9020.97
152_W213_W0.9010.97
46_V57_L0.8910.97
214_A222_S0.8870.97
103_E140_R0.8860.97
61_V74_I0.8670.97
81_L86_D0.8630.97
29_Q86_D0.8630.97
10_L13_L0.8620.97
136_K216_I0.8620.97
50_G53_T0.8560.97
148_V152_W0.8520.96
177_A216_I0.8510.96
87_S112_A0.8510.96
150_D154_S0.8470.96
32_R140_R0.8310.96
35_Y72_F0.8290.96
164_L179_L0.8240.96
157_F179_L0.8200.96
180_A183_K0.8200.96
101_N196_G0.8180.96
167_Y196_G0.8110.95
173_Y195_P0.8090.95
33_V44_L0.8050.95
152_W215_A0.8000.95
107_Y111_R0.8000.95
81_L87_S0.7890.95
59_S74_I0.7840.94
105_L173_Y0.7810.94
59_S110_V0.7810.94
143_H146_G0.7760.94
109_N132_K0.7760.94
182_D209_K0.7730.94
55_Y111_R0.7710.94
8_V13_L0.7630.94
79_F89_L0.7630.94
8_V11_T0.7630.94
63_N69_R0.7630.94
175_V190_I0.7620.93
106_F139_Y0.7560.93
25_G55_Y0.7550.93
30_R33_V0.7530.93
146_G151_A0.7520.93
11_T14_C0.7450.93
100_E143_H0.7360.92
27_V49_K0.7350.92
101_N140_R0.7300.92
13_L16_F0.7280.92
58_Q111_R0.7230.92
110_V135_I0.7220.92
176_F221_G0.7190.91
64_I107_Y0.7170.91
181_V211_V0.7160.91
125_N128_T0.7130.91
55_Y59_S0.7120.91
27_V133_T0.7110.91
34_I140_R0.7110.91
160_S200_Q0.7090.91
19_G23_A0.7060.91
61_V113_I0.7030.90
32_R141_P0.7020.90
45_P78_L0.7020.90
57_L81_L0.7000.90
130_V157_F0.7000.90
91_I108_I0.7000.90
49_K115_A0.7000.90
9_I12_L0.6980.90
146_G150_D0.6980.90
63_N70_A0.6960.90
109_N136_K0.6950.90
163_S203_L0.6940.90
78_L86_D0.6940.90
151_A157_F0.6910.90
13_L20_Q0.6890.90
32_R136_K0.6870.89
20_Q224_G0.6860.89
23_A164_L0.6770.89
35_Y39_R0.6770.89
81_L85_D0.6760.89
142_A145_K0.6750.89
25_G49_K0.6730.88
90_R114_P0.6720.88
164_L211_V0.6720.88
178_G185_D0.6700.88
119_S124_A0.6680.88
136_K140_R0.6610.88
136_K175_V0.6610.88
147_R172_Y0.6600.87
182_D187_T0.6590.87
152_W155_L0.6580.87
112_A130_V0.6580.87
152_W169_P0.6570.87
72_F139_Y0.6560.87
107_Y136_K0.6560.87
72_F104_S0.6550.87
54_P115_A0.6510.87
9_I17_C0.6500.87
179_L201_L0.6500.87
190_I201_L0.6490.87
64_I105_L0.6480.86
35_Y93_K0.6470.86
59_S87_S0.6410.86
28_L49_K0.6400.86
152_W170_T0.6340.85
102_K141_P0.6330.85
155_L215_A0.6300.85
31_T140_R0.6280.85
104_S139_Y0.6280.85
92_I195_P0.6250.84
131_F190_I0.6220.84
199_K202_P0.6200.84
12_L23_A0.6170.84
157_F164_L0.6150.84
18_I22_L0.6150.84
26_I55_Y0.6140.83
56_L111_R0.6140.83
14_C19_G0.6130.83
43_A129_L0.6100.83
35_Y40_K0.6090.83
127_L134_R0.6070.83
107_Y175_V0.6040.82
28_L56_L0.6030.82
149_N153_K0.6000.82
77_P113_I0.6000.82
46_V115_A0.5940.81
101_N104_S0.5930.81
148_V174_V0.5920.81
61_V106_F0.5910.81
14_C17_C0.5890.81
10_L14_C0.5870.81
56_L172_Y0.5850.80
112_A132_K0.5790.80
18_I23_A0.5770.79
193_I197_E0.5760.79
164_L200_Q0.5760.79
71_P104_S0.5730.79
36_D138_F0.5730.79
59_S79_F0.5710.79
184_T187_T0.5700.79
64_I134_R0.5700.79
15_S19_G0.5690.79
181_V210_N0.5620.78
20_Q23_A0.5620.78
107_Y110_V0.5610.78
50_G111_R0.5580.77
112_A175_V0.5550.77
58_Q90_R0.5530.77
60_W133_T0.5520.76
152_W157_F0.5500.76
98_L101_N0.5500.76
176_F213_W0.5480.76
180_A214_A0.5480.76
45_P129_L0.5480.76
173_Y197_E0.5460.76
162_H205_A0.5450.76
150_D224_G0.5420.75
186_L206_S0.5420.75
19_G22_L0.5410.75
189_K222_S0.5410.75
116_K128_T0.5400.75
141_P195_P0.5390.75
62_D129_L0.5390.75
62_D132_K0.5390.75
46_V110_V0.5370.74
42_A137_M0.5360.74
9_I200_Q0.5360.74
107_Y213_W0.5330.74
103_E218_D0.5330.74
214_A224_G0.5300.74
112_A213_W0.5290.73
84_G158_K0.5280.73
8_V12_L0.5280.73
213_W223_S0.5270.73
166_I193_I0.5260.73
56_L80_R0.5250.73
32_R218_D0.5250.73
55_Y81_L0.5240.73
179_L203_L0.5220.72
131_F134_R0.5220.72
205_A210_N0.5200.72
12_L210_N0.5200.72
114_P130_V0.5180.72
18_I158_K0.5180.72
56_L112_A0.5160.72
62_D111_R0.5130.71
20_Q202_P0.5110.71
184_T208_G0.5110.71
18_I67_K0.5090.71
182_D186_L0.5090.71
144_L171_E0.5070.70
140_R144_L0.5060.70
8_V20_Q0.5050.70
26_I46_V0.5030.70
107_Y132_K0.5020.70
28_L133_T0.5020.70
34_I136_K0.5020.70
98_L136_K0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2co7B 1 0.8528 100 0.122 Contact Map
1klfA 1 0.8831 100 0.126 Contact Map
1l4iA 2 0.8225 100 0.133 Contact Map
3q48A 1 0.8052 100 0.164 Contact Map
2xg5A 1 0.8615 100 0.168 Contact Map
4djmA 1 0.8701 100 0.169 Contact Map
4ay0A 2 0.8139 100 0.173 Contact Map
3gfuC 1 0.8442 100 0.178 Contact Map
4ncdA 2 0.8139 100 0.251 Contact Map
1mspA 3 0.4892 91.2 0.917 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0079 seconds.