GREMLIN Database
YRAH - Uncharacterized fimbrial-like protein YraH
UniProt: P42913 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12773
Length: 194 (164)
Sequences: 3290 (2598)
Seq/√Len: 202.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
128_I167_A3.2401.00
124_T179_T3.2181.00
94_F191_L2.8781.00
39_E77_N2.8661.00
61_N64_E2.7991.00
112_L127_G2.7361.00
129_R170_V2.6941.00
72_T162_N2.6531.00
129_R168_Y2.6421.00
131_D168_Y2.5781.00
41_N76_V2.4441.00
113_A141_L2.3941.00
125_G178_I2.3811.00
169_Y183_A2.3061.00
74_P162_N2.1351.00
60_R64_E2.1081.00
132_D137_N2.0311.00
115_V183_A2.0221.00
128_I185_A2.0071.00
72_T164_D1.9671.00
140_P143_A1.8571.00
136_G166_I1.8361.00
129_R138_I1.7441.00
17_A21_A1.7431.00
132_D135_S1.6971.00
113_A187_V1.6891.00
65_R129_R1.6121.00
68_K168_Y1.5821.00
70_P166_I1.5801.00
41_N74_P1.5521.00
32_E53_H1.5521.00
117_S122_A1.5351.00
99_E190_T1.5261.00
52_G69_I1.5091.00
12_L15_L1.4911.00
41_N44_D1.4901.00
54_Y66_S1.4871.00
93_S152_Q1.4701.00
111_N140_P1.4641.00
106_V172_T1.4201.00
44_D47_I1.4131.00
59_F171_S1.4121.00
100_T113_A1.3911.00
70_P164_D1.3761.00
99_E142_N1.3601.00
112_L170_V1.3471.00
47_I73_I1.3451.00
51_L169_Y1.3371.00
44_D74_P1.3361.00
96_L163_V1.3121.00
65_R168_Y1.2961.00
71_F130_I1.2611.00
112_L129_R1.2451.00
153_I161_V1.2451.00
59_F178_I1.2411.00
52_G183_A1.2411.00
106_V109_F1.2251.00
11_G14_A1.2221.00
125_G176_S1.2031.00
93_S150_V1.2031.00
52_G67_P1.1761.00
106_V110_P1.1601.00
28_V186_I1.1561.00
39_E76_V1.1441.00
95_R192_D1.1411.00
10_A13_L1.1121.00
51_L183_A1.1021.00
171_S178_I1.1001.00
59_F126_V1.0931.00
58_Q66_S1.0791.00
65_R170_V1.0721.00
65_R131_D1.0621.00
95_R150_V1.0621.00
97_W144_M1.0611.00
15_L18_G1.0601.00
94_F161_V1.0591.00
117_S182_E1.0531.00
25_G29_F1.0501.00
68_K166_I1.0481.00
133_A164_D1.0311.00
14_A18_G1.0271.00
127_G172_T1.0271.00
59_F172_T1.0231.00
116_G184_D1.0231.00
55_N58_Q0.9971.00
17_A20_A0.9911.00
9_I12_L0.9771.00
20_A23_T0.9711.00
25_G189_V0.9660.99
131_D166_I0.9660.99
171_S177_E0.9550.99
49_V71_F0.9520.99
110_P113_A0.9420.99
122_A182_E0.9370.99
154_P161_V0.9350.99
54_Y169_Y0.9340.99
13_L16_F0.9340.99
33_I178_I0.9220.99
123_A126_V0.9210.99
73_I189_V0.9060.99
61_N171_S0.9050.99
8_A15_L0.9010.99
35_K56_A0.9000.99
60_R171_S0.8990.99
128_I183_A0.8900.99
47_I189_V0.8870.99
51_L128_I0.8830.99
35_K79_P0.8760.99
42_D47_I0.8750.99
7_T10_A0.8740.99
26_E46_K0.8710.99
95_R148_N0.8700.99
97_W192_D0.8510.99
59_F64_E0.8510.99
30_D50_A0.8420.99
126_V169_Y0.8390.99
141_L185_A0.8360.99
62_I176_S0.8330.98
15_L19_N0.8300.98
130_I187_V0.8210.98
59_F176_S0.8150.98
10_A14_A0.8100.98
33_I54_Y0.8090.98
42_D45_K0.8090.98
107_P110_P0.8030.98
116_G186_I0.8010.98
81_T92_A0.7970.98
75_L161_V0.7970.98
54_Y183_A0.7950.98
96_L191_L0.7870.98
130_I141_L0.7830.98
148_N151_Y0.7820.98
54_Y59_F0.7780.98
8_A12_L0.7750.98
7_T11_G0.7730.98
30_D48_E0.7720.98
13_L17_A0.7710.98
98_L165_L0.7520.97
51_L167_A0.7450.97
107_P127_G0.7420.97
106_V112_L0.7400.97
8_A11_G0.7360.97
113_A185_A0.7340.97
106_V111_N0.7330.97
139_M165_L0.7310.97
98_L130_I0.7260.96
131_D136_G0.7200.96
106_V127_G0.7190.96
112_L115_V0.7190.96
56_A178_I0.7180.96
51_L69_I0.7160.96
105_T110_P0.7120.96
118_F122_A0.7090.96
131_D138_I0.7070.96
62_I125_G0.7010.96
50_A69_I0.6880.95
50_A169_Y0.6860.95
66_S169_Y0.6840.95
104_G114_K0.6840.95
6_K13_L0.6800.95
9_I13_L0.6790.95
33_I115_V0.6760.95
100_T105_T0.6670.94
37_A169_Y0.6620.94
8_A17_A0.6600.94
74_P160_I0.6570.94
105_T111_N0.6530.94
79_P131_D0.6490.93
137_N149_T0.6490.93
28_V46_K0.6480.93
141_L165_L0.6460.93
64_E171_S0.6440.93
94_F153_I0.6410.93
154_P159_G0.6410.93
172_T175_P0.6390.93
68_K131_D0.6390.93
56_A180_P0.6360.93
135_S166_I0.6330.93
7_T18_G0.6300.92
148_N153_I0.6290.92
97_W100_T0.6240.92
115_V184_D0.6190.92
123_A185_A0.6130.91
16_F20_A0.6130.91
28_V48_E0.6120.91
149_T152_Q0.6080.91
18_G21_A0.6070.91
7_T14_A0.6050.91
98_L191_L0.6030.91
79_P82_G0.6030.91
75_L191_L0.6020.91
51_L129_R0.6010.91
99_E188_N0.5990.90
62_I171_S0.5930.90
7_T15_L0.5910.90
25_G31_G0.5880.90
11_G19_N0.5840.89
12_L16_F0.5830.89
37_A80_M0.5830.89
126_V171_S0.5810.89
69_I167_A0.5770.89
50_A53_H0.5690.88
141_L187_V0.5660.88
19_N23_T0.5660.88
18_G22_A0.5640.88
132_D136_G0.5640.88
118_F182_E0.5630.88
7_T13_L0.5630.88
10_A22_A0.5630.88
60_R178_I0.5540.87
115_V118_F0.5530.87
20_A24_D0.5510.86
171_S176_S0.5510.86
15_L62_I0.5490.86
65_R68_K0.5470.86
33_I183_A0.5460.86
58_Q67_P0.5450.86
80_M92_A0.5440.86
51_L71_F0.5430.86
76_V160_I0.5420.86
133_A151_Y0.5410.85
11_G15_L0.5390.85
169_Y184_D0.5360.85
108_N172_T0.5350.85
98_L189_V0.5350.85
49_V167_A0.5340.85
9_I21_A0.5330.85
97_W143_A0.5330.85
125_G172_T0.5290.84
126_V178_I0.5280.84
111_N127_G0.5270.84
27_I71_F0.5200.83
59_F63_G0.5190.83
80_M155_A0.5180.83
52_G184_D0.5140.82
109_F112_L0.5140.82
33_I167_A0.5140.82
138_I141_L0.5130.82
15_L50_A0.5110.82
52_G169_Y0.5110.82
43_S46_K0.5100.82
9_I16_F0.5100.82
95_R144_M0.5090.82
115_V169_Y0.5060.81
98_L139_M0.5060.81
135_S149_T0.5000.81
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2jmrA 1 0.799 100 0.253 Contact Map
2xg5B 1 0.7577 100 0.273 Contact Map
2jtyA 1 0.8144 100 0.281 Contact Map
2uy6B 2 0.7938 100 0.306 Contact Map
1pdkB 1 0.7423 100 0.314 Contact Map
3bwuF 1 0.6598 99.9 0.358 Contact Map
2w07B 1 0.6134 99.9 0.386 Contact Map
4dwhB 1 0.7062 99.9 0.388 Contact Map
3bfqG 1 0.6804 99.9 0.395 Contact Map
5afoA 1 0.8814 99.9 0.403 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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