YHBX - ECOLI - GREMLIN Contacts

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YHBX - Putative phosphoethanolamine transferase YhbX

UniProt:	P42640	Sequences: MTVFNKFARTFKSHWLLYLCVIVFGITNLVASSGAHMVQRLLFFVLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDPDEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQFAYKDAKNKKAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVRDTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVPLSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETVYVRGFDELLLPHLSQALQQNTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDACYDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHVPMFIWYSPVLGDGVDRTTENNIFSTAYNNYLINAWMGVTKPEQPQTLEEVIAHYKGDSRVVDANHDVFDYVMLRKEFTEDKQGNPTPEGQG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12793
Length:	541 (476)
Sequences:	5540 (4735)
Seq/√Len:	217.0

ECOLI - YHBX EPTC OPGE EPTA EPTB YEJM YJGX YIDJ
BACSU - LTAS1 LTAS2 YQGS YVGJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
250_Q	405_G	5.929	1.00
262_N	470_N	5.494	1.00
484_A	498_E	4.494	1.00
301_N	329_R	4.409	1.00
250_Q	253_A	3.873	1.00
25_G	28_N	3.849	1.00
352_Q	414_R	3.758	1.00
306_Q	357_Q	3.474	1.00
348_S	410_L	3.473	1.00
331_M	335_Y	3.372	1.00
228_I	420_Y	3.214	1.00
246_S	252_E	3.168	1.00
226_V	418_V	3.154	1.00
405_G	409_E	3.085	1.00
473_F	499_E	2.938	1.00
22_I	25_G	2.922	1.00
409_E	412_K	2.770	1.00
224_T	416_A	2.690	1.00
225_Y	300_A	2.687	1.00
225_Y	486_M	2.682	1.00
481_L	500_V	2.653	1.00
264_A	473_F	2.652	1.00
230_G	233_V	2.636	1.00
223_D	415_R	2.539	1.00
257_Q	412_K	2.490	1.00
36_H	40_R	2.488	1.00
239_S	248_T	2.437	1.00
280_T	295_N	2.420	1.00
411_L	418_V	2.296	1.00
300_A	486_M	2.276	1.00
224_T	359_K	2.199	1.00
25_G	29_L	2.193	1.00
228_I	404_L	2.183	1.00
346_H	349_Q	2.169	1.00
408_F	418_V	2.149	1.00
227_L	360_L	2.126	1.00
333_T	336_V	2.089	1.00
406_Q	409_E	2.048	1.00
409_E	413_D	2.047	1.00
248_T	252_E	2.023	1.00
141_K	144_G	2.002	1.00
226_V	416_A	1.972	1.00
417_S	454_I	1.966	1.00
341_E	406_Q	1.959	1.00
344_L	348_S	1.941	1.00
350_A	353_Q	1.940	1.00
377_P	399_Y	1.914	1.00
241_Y	260_L	1.877	1.00
271_T	364_H	1.871	1.00
127_L	131_I	1.865	1.00
221_G	415_R	1.854	1.00
347_L	363_L	1.826	1.00
249_P	401_D	1.823	1.00
117_C	121_F	1.790	1.00
378_Q	381_A	1.779	1.00
227_L	419_M	1.757	1.00
348_S	414_R	1.714	1.00
20_C	25_G	1.713	1.00
278_S	421_F	1.707	1.00
382_V	398_H	1.703	1.00
24_F	28_N	1.698	1.00
22_I	28_N	1.688	1.00
348_S	352_Q	1.674	1.00
368_S	396_S	1.666	1.00
183_T	186_P	1.649	1.00
19_L	25_G	1.628	1.00
310_L	350_A	1.625	1.00
369_H	423_D	1.616	1.00
160_Q	164_K	1.601	1.00
20_C	28_N	1.590	1.00
341_E	399_Y	1.582	1.00
421_F	475_T	1.571	1.00
125_L	129_V	1.570	1.00
422_A	450_V	1.570	1.00
178_A	184_Y	1.569	1.00
419_M	454_I	1.562	1.00
332_E	335_Y	1.554	1.00
182_A	185_T	1.550	1.00
398_H	402_S	1.541	1.00
78_S	88_T	1.530	1.00
183_T	188_F	1.524	1.00
445_Q	448_Y	1.519	1.00
444_S	447_A	1.513	1.00
340_D	344_L	1.510	1.00
443_A	447_A	1.503	1.00
223_D	417_S	1.503	1.00
239_S	252_E	1.486	1.00
161_F	164_K	1.484	1.00
233_V	397_I	1.478	1.00
344_L	365_L	1.471	1.00
264_A	452_M	1.469	1.00
202_R	205_S	1.464	1.00
229_V	275_V	1.463	1.00
239_S	246_S	1.461	1.00
233_V	400_T	1.452	1.00
402_S	406_Q	1.450	1.00
32_S	36_H	1.443	1.00
159_C	163_Y	1.431	1.00
410_L	413_D	1.429	1.00
160_Q	165_D	1.428	1.00
210_V	214_Q	1.425	1.00
262_N	468_T	1.422	1.00
230_G	420_Y	1.412	1.00
406_Q	410_L	1.408	1.00
26_I	29_L	1.387	1.00
17_L	25_G	1.386	1.00
39_Q	43_F	1.384	1.00
407_V	418_V	1.381	1.00
402_S	405_G	1.364	1.00
251_V	404_L	1.360	1.00
154_S	157_S	1.359	1.00
310_L	361_I	1.353	1.00
33_S	40_R	1.351	1.00
281_A	480_Y	1.349	1.00
410_L	414_R	1.343	1.00
230_G	400_T	1.343	1.00
349_Q	353_Q	1.342	1.00
380_S	402_S	1.340	1.00
456_Y	460_L	1.339	1.00
214_Q	217_V	1.337	1.00
237_N	394_D	1.333	1.00
40_R	43_F	1.329	1.00
308_F	359_K	1.327	1.00
299_M	483_N	1.320	1.00
178_A	181_F	1.319	1.00
250_Q	401_D	1.318	1.00
182_A	186_P	1.304	1.00
452_M	478_N	1.303	1.00
37_M	40_R	1.295	1.00
136_S	139_T	1.293	1.00
203_L	207_A	1.289	1.00
124_L	128_A	1.285	1.00
23_V	26_I	1.285	1.00
296_I	482_I	1.278	1.00
320_G	324_T	1.276	1.00
368_S	397_I	1.275	1.00
120_A	123_S	1.273	1.00
40_R	44_F	1.271	1.00
403_L	406_Q	1.268	1.00
230_G	404_L	1.257	1.00
182_A	187_F	1.249	1.00
229_V	421_F	1.240	1.00
315_A	320_G	1.227	1.00
253_A	405_G	1.225	1.00
225_Y	417_S	1.224	1.00
183_T	189_N	1.223	1.00
117_C	123_S	1.222	1.00
104_E	107_K	1.220	1.00
143_T	147_L	1.215	1.00
258_I	455_W	1.215	1.00
335_Y	338_G	1.208	1.00
180_R	184_Y	1.205	1.00
24_F	27_T	1.200	1.00
161_F	165_D	1.190	1.00
248_T	251_V	1.186	1.00
343_L	363_L	1.186	1.00
182_A	188_F	1.186	1.00
445_Q	449_H	1.185	1.00
180_R	183_T	1.184	1.00
151_I	155_L	1.171	1.00
181_F	186_P	1.166	1.00
116_L	119_F	1.163	1.00
235_V	449_H	1.160	1.00
156_F	160_Q	1.154	1.00
227_L	278_S	1.154	1.00
419_M	482_I	1.148	1.00
101_D	104_E	1.140	1.00
13_S	22_I	1.138	1.00
204_L	208_N	1.135	1.00
123_S	126_F	1.132	1.00
152_S	156_F	1.120	1.00
408_F	412_K	1.120	1.00
128_A	132_K	1.117	1.00
22_I	26_I	1.112	1.00
316_F	320_G	1.112	1.00
261_F	452_M	1.111	1.00
169_K	172_F	1.107	1.00
184_Y	188_F	1.104	1.00
18_Y	25_G	1.103	1.00
140_K	143_T	1.103	1.00
363_L	407_V	1.102	1.00
176_I	181_F	1.098	1.00
308_F	361_I	1.089	1.00
250_Q	402_S	1.088	1.00
250_Q	408_F	1.086	1.00
33_S	36_H	1.085	1.00
142_V	145_I	1.085	1.00
17_L	20_C	1.085	1.00
309_W	323_V	1.085	1.00
271_T	369_H	1.083	1.00
186_P	189_N	1.079	1.00
233_V	251_V	1.077	1.00
368_S	400_T	1.076	1.00
332_E	336_V	1.076	1.00
49_L	52_K	1.073	1.00
225_Y	360_L	1.070	1.00
233_V	238_M	1.069	1.00
20_C	24_F	1.067	1.00
140_K	144_G	1.066	1.00
144_G	161_F	1.065	1.00
227_L	478_N	1.060	1.00
352_Q	410_L	1.060	1.00
245_R	394_D	1.059	1.00
189_N	192_Y	1.059	1.00
118_A	122_L	1.057	1.00
403_L	407_V	1.055	1.00
17_L	21_V	1.055	1.00
18_Y	22_I	1.055	1.00
381_A	386_Q	1.053	1.00
32_S	40_R	1.053	1.00
227_L	362_V	1.052	1.00
344_L	407_V	1.052	1.00
259_K	500_V	1.051	1.00
309_W	364_H	1.051	1.00
179_S	183_T	1.050	1.00
186_P	190_L	1.047	1.00
483_N	488_V	1.044	1.00
135_V	138_P	1.041	1.00
308_F	350_A	1.040	1.00
381_A	384_Q	1.038	1.00
243_Y	394_D	1.037	1.00
347_L	351_L	1.034	1.00
154_S	158_A	1.032	1.00
229_V	362_V	1.031	1.00
373_C	392_C	1.030	1.00
254_Q	404_L	1.029	1.00
311_S	319_N	1.029	1.00
172_F	175_Y	1.025	1.00
183_T	187_F	1.025	1.00
305_F	358_K	1.023	1.00
19_L	22_I	1.023	1.00
147_L	151_I	1.020	1.00
279_L	360_L	1.020	1.00
437_F	440_G	1.018	1.00
259_K	469_E	1.018	1.00
180_R	185_T	1.017	1.00
210_V	213_F	1.015	1.00
192_Y	195_L	1.011	1.00
308_F	330_A	1.010	1.00
376_Y	395_N	1.008	1.00
253_A	257_Q	1.007	1.00
303_A	488_V	1.004	1.00
21_V	25_G	1.004	1.00
417_S	456_Y	1.003	1.00
237_N	397_I	1.002	1.00
119_F	123_S	0.992	1.00
204_L	207_A	0.991	1.00
128_A	131_I	0.990	1.00
254_Q	408_F	0.986	1.00
50_V	55_S	0.986	1.00
52_K	55_S	0.985	1.00
231_E	423_D	0.984	1.00
234_R	425_G	0.982	1.00
233_V	248_T	0.982	1.00
436_Y	439_G	0.981	1.00
294_D	302_Q	0.981	1.00
278_S	478_N	0.980	1.00
185_T	188_F	0.980	1.00
129_V	133_Y	0.977	1.00
178_A	183_T	0.977	1.00
346_H	350_A	0.977	1.00
383_F	395_N	0.977	1.00
185_T	189_N	0.976	1.00
345_P	406_Q	0.974	1.00
309_W	313_Q	0.974	1.00
183_T	193_F	0.974	1.00
205_S	208_N	0.974	1.00
377_P	380_S	0.972	1.00
158_A	161_F	0.970	1.00
17_L	24_F	0.968	1.00
46_L	50_V	0.966	1.00
229_V	278_S	0.965	1.00
214_Q	218_R	0.964	1.00
13_S	24_F	0.961	1.00
267_G	277_L	0.954	1.00
316_F	319_N	0.952	1.00
185_T	192_Y	0.952	1.00
421_F	478_N	0.950	1.00
50_V	53_R	0.944	1.00
182_A	189_N	0.943	1.00
181_F	184_Y	0.937	1.00
150_V	153_G	0.936	1.00
178_A	182_A	0.930	0.99
225_Y	305_F	0.929	0.99
462_D	466_R	0.927	0.99
498_E	501_I	0.927	0.99
19_L	23_V	0.927	0.99
263_Q	472_I	0.925	0.99
300_A	483_N	0.924	0.99
458_P	461_G	0.919	0.99
179_S	182_A	0.917	0.99
120_A	124_L	0.913	0.99
181_F	188_F	0.911	0.99
480_Y	496_T	0.910	0.99
184_Y	189_N	0.910	0.99
151_I	154_S	0.908	0.99
226_V	359_K	0.905	0.99
297_I	328_M	0.903	0.99
265_I	449_H	0.903	0.99
351_L	411_L	0.901	0.99
342_L	345_P	0.899	0.99
222_I	303_A	0.896	0.99
158_A	162_A	0.893	0.99
271_T	423_D	0.892	0.99
267_G	474_S	0.891	0.99
19_L	24_F	0.884	0.99
383_F	398_H	0.884	0.99
47_T	51_V	0.883	0.99
223_D	358_K	0.881	0.99
36_H	39_Q	0.880	0.99
231_E	369_H	0.878	0.99
188_F	192_Y	0.878	0.99
148_L	152_S	0.877	0.99
123_S	127_L	0.875	0.99
233_V	237_N	0.874	0.99
250_Q	254_Q	0.873	0.99
158_A	165_D	0.873	0.99
318_Q	321_T	0.872	0.99
33_S	37_M	0.869	0.99
426_L	438_H	0.868	0.99
345_P	348_S	0.867	0.99
263_Q	449_H	0.865	0.99
180_R	186_P	0.864	0.99
21_V	28_N	0.863	0.99
69_L	73_A	0.863	0.99
160_Q	163_Y	0.861	0.99
144_G	164_K	0.860	0.99
304_G	358_K	0.859	0.99
144_G	156_F	0.859	0.99
184_Y	192_Y	0.856	0.99
225_Y	419_M	0.854	0.99
176_I	179_S	0.854	0.99
46_L	51_V	0.852	0.99
213_F	216_S	0.852	0.99
156_F	164_K	0.851	0.99
230_G	344_L	0.850	0.99
32_S	39_Q	0.849	0.99
345_P	410_L	0.849	0.99
168_N	172_F	0.848	0.99
146_L	153_G	0.845	0.99
450_V	475_T	0.840	0.99
417_S	482_I	0.837	0.99
15_W	25_G	0.836	0.99
365_L	400_T	0.834	0.99
203_L	206_I	0.833	0.99
144_G	159_C	0.832	0.99
33_S	39_Q	0.832	0.99
319_N	323_V	0.828	0.99
151_I	158_A	0.828	0.99
52_K	56_S	0.828	0.99
349_Q	352_Q	0.827	0.99
372_A	426_L	0.826	0.99
215_L	218_R	0.825	0.99
178_A	186_P	0.824	0.99
32_S	38_V	0.824	0.99
227_L	421_F	0.823	0.99
105_V	108_M	0.823	0.99
183_T	191_N	0.822	0.99
178_A	187_F	0.820	0.99
180_R	189_N	0.819	0.99
272_A	317_R	0.816	0.99
332_E	337_R	0.813	0.99
162_A	165_D	0.813	0.99
404_L	420_Y	0.812	0.99
299_M	302_Q	0.812	0.99
250_Q	409_E	0.811	0.99
101_D	105_V	0.811	0.99
126_F	130_I	0.810	0.99
249_P	254_Q	0.810	0.99
51_V	55_S	0.808	0.99
40_R	45_V	0.808	0.99
258_I	453_F	0.807	0.99
156_F	165_D	0.804	0.98
228_I	418_V	0.802	0.98
198_K	203_L	0.802	0.98
184_Y	190_L	0.802	0.98
159_C	164_K	0.800	0.98
169_K	175_Y	0.800	0.98
159_C	162_A	0.800	0.98
233_V	420_Y	0.799	0.98
344_L	400_T	0.797	0.98
347_L	361_I	0.797	0.98
306_Q	330_A	0.797	0.98
14_H	18_Y	0.795	0.98
144_G	148_L	0.794	0.98
239_S	256_K	0.794	0.98
144_G	163_Y	0.793	0.98
228_I	344_L	0.791	0.98
328_M	362_V	0.789	0.98
300_A	360_L	0.788	0.98
341_E	402_S	0.787	0.98
466_R	469_E	0.786	0.98
226_V	407_V	0.784	0.98
149_I	153_G	0.781	0.98
438_H	441_R	0.780	0.98
319_N	322_A	0.780	0.98
367_G	399_Y	0.780	0.98
253_A	256_K	0.779	0.98
179_S	184_Y	0.776	0.98
24_F	29_L	0.772	0.98
103_D	107_K	0.769	0.98
280_T	322_A	0.768	0.98
157_S	162_A	0.767	0.98
15_W	29_L	0.765	0.98
227_L	296_I	0.764	0.98
190_L	193_F	0.762	0.98
124_L	127_L	0.762	0.98
102_P	106_V	0.761	0.98
147_L	158_A	0.760	0.98
38_V	42_L	0.759	0.98
443_A	448_Y	0.758	0.98
342_L	346_H	0.757	0.98
229_V	364_H	0.756	0.98
305_F	486_M	0.755	0.98
36_H	42_L	0.755	0.98
171_A	174_P	0.754	0.98
331_M	337_R	0.753	0.98
180_R	187_F	0.752	0.98
211_P	214_Q	0.751	0.98
255_R	260_L	0.748	0.98
190_L	194_A	0.745	0.98
365_L	403_L	0.743	0.97
191_N	195_L	0.743	0.97
41_L	45_V	0.741	0.97
376_Y	381_A	0.741	0.97
181_F	185_T	0.740	0.97
351_L	361_I	0.738	0.97
226_V	351_L	0.738	0.97
157_S	161_F	0.737	0.97
381_A	385_P	0.736	0.97
408_F	420_Y	0.736	0.97
33_S	38_V	0.735	0.97
181_F	193_F	0.735	0.97
435_V	440_G	0.735	0.97
461_G	466_R	0.734	0.97
333_T	337_R	0.733	0.97
301_N	307_T	0.733	0.97
35_A	40_R	0.733	0.97
23_V	28_N	0.731	0.97
297_I	307_T	0.731	0.97
376_Y	380_S	0.730	0.97
235_V	241_Y	0.730	0.97
104_E	108_M	0.729	0.97
255_R	258_I	0.729	0.97
393_Y	397_I	0.728	0.97
64_A	67_F	0.726	0.97
369_H	424_H	0.722	0.97
39_Q	42_L	0.721	0.97
437_F	441_R	0.719	0.97
34_G	40_R	0.717	0.97
421_F	450_V	0.717	0.97
251_V	453_F	0.717	0.97
48_I	52_K	0.716	0.97
159_C	165_D	0.716	0.97
166_A	173_S	0.716	0.97
443_A	446_Q	0.714	0.97
108_M	112_Y	0.714	0.97
257_Q	261_F	0.712	0.97
50_V	54_I	0.712	0.97
331_M	336_V	0.711	0.97
367_G	396_S	0.709	0.97
317_R	322_A	0.708	0.97
321_T	324_T	0.707	0.97
183_T	190_L	0.705	0.97
254_Q	453_F	0.705	0.97
420_Y	453_F	0.704	0.97
395_N	398_H	0.703	0.96
194_A	197_A	0.702	0.96
331_M	334_V	0.701	0.96
189_N	193_F	0.701	0.96
210_V	216_S	0.700	0.96
13_S	25_G	0.700	0.96
213_F	217_V	0.699	0.96
201_Q	204_L	0.699	0.96
281_A	293_P	0.695	0.96
259_K	467_T	0.694	0.96
198_K	206_I	0.692	0.96
171_A	175_Y	0.692	0.96
31_A	38_V	0.692	0.96
13_S	16_L	0.692	0.96
271_T	275_V	0.689	0.96
344_L	403_L	0.688	0.96
222_I	358_K	0.687	0.96
247_T	394_D	0.686	0.96
319_N	326_I	0.685	0.96
104_E	112_Y	0.683	0.96
484_A	501_I	0.682	0.96
261_F	265_I	0.680	0.96
184_Y	187_F	0.675	0.96
211_P	215_L	0.673	0.96
156_F	163_Y	0.671	0.95
313_Q	364_H	0.669	0.95
200_H	204_L	0.668	0.95
49_L	55_S	0.665	0.95
189_N	194_A	0.663	0.95
334_V	337_R	0.662	0.95
188_F	191_N	0.661	0.95
146_L	159_C	0.660	0.95
170_K	173_S	0.659	0.95
312_S	366_N	0.655	0.95
129_V	134_D	0.655	0.95
235_V	260_L	0.655	0.95
35_A	38_V	0.652	0.95
166_A	172_F	0.649	0.95
380_S	399_Y	0.648	0.94
417_S	460_L	0.646	0.94
153_G	165_D	0.646	0.94
252_E	255_R	0.645	0.94
176_I	180_R	0.645	0.94
176_I	183_T	0.643	0.94
176_I	185_T	0.643	0.94
399_Y	402_S	0.643	0.94
16_L	20_C	0.643	0.94
202_R	206_I	0.642	0.94
116_L	121_F	0.642	0.94
225_Y	482_I	0.641	0.94
313_Q	366_N	0.641	0.94
141_K	145_I	0.640	0.94
236_D	446_Q	0.639	0.94
22_I	29_L	0.638	0.94
40_R	56_S	0.637	0.94
479_N	483_N	0.636	0.94
268_A	287_H	0.636	0.94
188_F	193_F	0.636	0.94
296_I	479_N	0.636	0.94
317_R	323_V	0.636	0.94
119_F	131_I	0.633	0.94
59_L	62_L	0.632	0.94
32_S	35_A	0.632	0.94
388_D	391_A	0.631	0.94
34_G	37_M	0.630	0.94
45_V	49_L	0.628	0.94
400_T	403_L	0.628	0.94
157_S	165_D	0.627	0.93
14_H	21_V	0.625	0.93
379_S	382_V	0.625	0.93
339_F	342_L	0.624	0.93
144_G	155_L	0.624	0.93
170_K	175_Y	0.623	0.93
404_L	418_V	0.623	0.93
180_R	192_Y	0.622	0.93
178_A	185_T	0.620	0.93
14_H	28_N	0.620	0.93
17_L	27_T	0.617	0.93
405_G	408_F	0.617	0.93
125_L	128_A	0.617	0.93
153_G	161_F	0.616	0.93
104_E	109_L	0.616	0.93
155_L	159_C	0.614	0.93
233_V	368_S	0.614	0.93
116_L	123_S	0.613	0.93
31_A	36_H	0.612	0.93
310_L	343_L	0.612	0.93
126_F	129_V	0.609	0.92
50_V	57_L	0.608	0.92
185_T	190_L	0.607	0.92
140_K	163_Y	0.607	0.92
116_L	131_I	0.606	0.92
157_S	164_K	0.606	0.92
297_I	360_L	0.605	0.92
311_S	314_S	0.605	0.92
34_G	42_L	0.604	0.92
426_L	447_A	0.604	0.92
156_F	159_C	0.604	0.92
279_L	362_V	0.602	0.92
240_L	247_T	0.602	0.92
206_I	209_T	0.599	0.92
266_S	425_G	0.597	0.92
180_R	188_F	0.596	0.92
168_N	171_A	0.596	0.92
155_L	158_A	0.596	0.92
16_L	24_F	0.595	0.92
199_E	203_L	0.595	0.92
153_G	156_F	0.594	0.92
143_T	146_L	0.594	0.92
254_Q	420_Y	0.593	0.91
186_P	193_F	0.592	0.91
77_I	89_F	0.592	0.91
277_L	475_T	0.591	0.91
239_S	247_T	0.591	0.91
93_F	96_S	0.591	0.91
436_Y	440_G	0.591	0.91
311_S	317_R	0.591	0.91
319_N	331_M	0.591	0.91
234_R	428_R	0.590	0.91
21_V	24_F	0.590	0.91
446_Q	449_H	0.590	0.91
30_V	35_A	0.589	0.91
78_S	89_F	0.588	0.91
40_R	57_L	0.587	0.91
231_E	365_L	0.587	0.91
191_N	194_A	0.586	0.91
21_V	26_I	0.585	0.91
167_K	171_A	0.584	0.91
321_T	325_S	0.584	0.91
179_S	186_P	0.584	0.91
198_K	202_R	0.583	0.91
143_T	154_S	0.582	0.91
121_F	125_L	0.581	0.91
144_G	160_Q	0.580	0.91
49_L	56_S	0.579	0.90
81_S	90_N	0.579	0.90
153_G	157_S	0.577	0.90
14_H	20_C	0.576	0.90
427_E	447_A	0.574	0.90
223_D	305_F	0.572	0.90
238_M	248_T	0.571	0.90
23_V	27_T	0.571	0.90
185_T	193_F	0.569	0.90
181_F	190_L	0.569	0.90
126_F	133_Y	0.566	0.89
170_K	174_P	0.565	0.89
323_V	328_M	0.565	0.89
496_T	499_E	0.564	0.89
15_W	20_C	0.564	0.89
34_G	38_V	0.562	0.89
17_L	23_V	0.562	0.89
117_C	120_A	0.562	0.89
306_Q	329_R	0.561	0.89
188_F	194_A	0.561	0.89
49_L	53_R	0.559	0.89
340_D	343_L	0.559	0.89
133_Y	136_S	0.559	0.89
145_I	160_Q	0.559	0.89
143_T	148_L	0.558	0.89
178_A	189_N	0.558	0.89
157_S	160_Q	0.557	0.89
457_S	460_L	0.555	0.89
186_P	195_L	0.555	0.89
275_V	311_S	0.553	0.88
186_P	191_N	0.553	0.88
17_L	29_L	0.553	0.88
36_H	43_F	0.551	0.88
271_T	424_H	0.551	0.88
380_S	398_H	0.550	0.88
436_Y	441_R	0.548	0.88
199_E	206_I	0.548	0.88
200_H	203_L	0.548	0.88
16_L	27_T	0.547	0.88
184_Y	193_F	0.547	0.88
258_I	262_N	0.545	0.88
420_Y	455_W	0.544	0.88
387_D	391_A	0.544	0.88
232_S	424_H	0.541	0.87
417_S	485_W	0.541	0.87
276_P	282_D	0.541	0.87
130_I	134_D	0.540	0.87
495_Q	498_E	0.539	0.87
129_V	132_K	0.539	0.87
183_T	192_Y	0.539	0.87
249_P	252_E	0.539	0.87
452_M	473_F	0.537	0.87
69_L	72_A	0.537	0.87
230_G	368_S	0.537	0.87
167_K	173_S	0.535	0.87
380_S	383_F	0.535	0.87
179_S	188_F	0.534	0.87
247_T	252_E	0.534	0.87
65_A	68_V	0.533	0.87
311_S	364_H	0.533	0.87
20_C	26_I	0.533	0.87
101_D	108_M	0.533	0.87
269_P	288_D	0.533	0.87
155_L	165_D	0.533	0.87
102_P	105_V	0.533	0.87
141_K	146_L	0.532	0.86
322_A	327_A	0.532	0.86
158_A	163_Y	0.530	0.86
148_L	151_I	0.530	0.86
16_L	23_V	0.528	0.86
347_L	407_V	0.526	0.86
20_C	23_V	0.526	0.86
21_V	27_T	0.524	0.86
468_T	471_N	0.524	0.86
238_M	241_Y	0.524	0.86
224_T	414_R	0.523	0.85
184_Y	191_N	0.523	0.85
47_T	54_I	0.522	0.85
444_S	448_Y	0.521	0.85
391_A	395_N	0.520	0.85
18_Y	28_N	0.519	0.85
178_A	188_F	0.519	0.85
149_I	156_F	0.516	0.85
341_E	345_P	0.516	0.85
243_Y	247_T	0.516	0.85
179_S	185_T	0.515	0.85
231_E	340_D	0.514	0.85
70_L	74_D	0.514	0.85
316_F	323_V	0.512	0.84
64_A	68_V	0.511	0.84
13_S	19_L	0.511	0.84
201_Q	207_A	0.511	0.84
180_R	191_N	0.510	0.84
232_S	423_D	0.510	0.84
275_V	319_N	0.510	0.84
237_N	247_T	0.509	0.84
234_R	274_S	0.509	0.84
23_V	29_L	0.508	0.84
246_S	398_H	0.507	0.84
305_F	417_S	0.506	0.84
296_I	360_L	0.506	0.84
234_R	393_Y	0.505	0.83
158_A	164_K	0.504	0.83
383_F	391_A	0.504	0.83
251_V	260_L	0.502	0.83
205_S	209_T	0.501	0.83
15_W	19_L	0.501	0.83
31_A	34_G	0.501	0.83
224_T	358_K	0.501	0.83
121_F	133_Y	0.501	0.83
106_V	110_G	0.501	0.83
248_T	401_D	0.500	0.83
232_S	422_A	0.500	0.83
92_G	95_I	0.500	0.83

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2w5qA	1	0.6192	100	0.5	Contact Map
4uorA	3	0.6118	100	0.501	Contact Map
2w8dA	1	0.6211	100	0.511	Contact Map
4upkA	3	0.5693	100	0.518	Contact Map
4kavA	1	0.5527	100	0.521	Contact Map
4tn0A	1	0.5323	100	0.522	Contact Map
2vqrA	3	0.5712	100	0.523	Contact Map
3lxqA	1	0.6063	100	0.524	Contact Map
4uopA	2	0.6229	100	0.525	Contact Map
3b5qA	1	0.5656	100	0.528	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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