GREMLIN Database
YQJC - Protein YqjC
UniProt: P42616 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12742
Length: 122 (113)
Sequences: 326 (237)
Seq/√Len: 22.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
39_E51_N4.0691.00
31_I57_V3.7951.00
52_K56_E3.1121.00
62_S65_Q3.0631.00
28_E58_R2.8810.99
81_V107_L2.8680.99
85_Q111_Q2.7120.99
23_L26_E2.4270.98
80_E103_R2.3780.97
85_Q89_A2.3250.97
78_K118_E2.3040.97
87_D103_R2.1810.96
35_I47_I2.1730.96
89_A92_K2.1600.95
84_R110_A2.0760.94
34_E46_R2.0180.93
84_R103_R1.8140.89
71_Q75_A1.7850.88
108_A111_Q1.5100.78
81_V110_A1.5060.78
31_I49_G1.5050.77
35_I56_E1.5050.77
26_E70_H1.4990.77
80_E87_D1.4910.77
94_K103_R1.4330.74
80_E110_A1.3970.72
74_I81_V1.3660.70
70_H117_L1.3440.69
85_Q115_K1.3340.68
33_K46_R1.3110.67
56_E60_N1.2980.66
80_E91_A1.2910.66
90_E115_K1.2690.64
25_Q70_H1.2670.64
107_L114_L1.2120.61
32_L36_S1.2090.60
8_A40_K1.2080.60
26_E63_D1.1960.60
10_S19_Y1.1450.56
104_E108_A1.1360.56
31_I39_E1.1200.55
27_K109_E1.0960.53
87_D91_A1.0730.51
23_L66_L1.0730.51
8_A11_L1.0710.51
27_K113_E1.0690.51
77_Q103_R1.0590.50
87_D94_K1.0550.50
34_E65_Q1.0390.49
40_K74_I1.0200.48
76_K87_D1.0110.47
9_V14_L1.0030.47
83_E109_E1.0010.46
48_D51_N0.9990.46
51_N55_S0.9820.45
22_T26_E0.9610.44
99_K106_K0.9530.43
40_K72_K0.9530.43
81_V117_L0.9490.43
23_L70_H0.9440.43
103_R110_A0.9420.42
44_Q48_D0.9360.42
59_A64_S0.9310.42
87_D96_D0.9290.42
72_K111_Q0.9230.41
101_A104_E0.9120.40
36_S39_E0.9110.40
35_I39_E0.9110.40
25_Q28_E0.9030.40
84_R95_G0.9020.40
15_S82_A0.8990.40
63_D119_A0.8930.39
92_K104_E0.8820.38
115_K118_E0.8670.37
34_E100_I0.8640.37
82_A111_Q0.8630.37
77_Q87_D0.8570.37
21_T26_E0.8510.36
98_D102_K0.8450.36
71_Q93_Q0.8240.35
35_I40_K0.8200.35
59_A111_Q0.8180.34
7_L68_A0.8050.34
80_E84_R0.7990.33
84_R100_I0.7910.33
31_I51_N0.7870.33
27_K88_L0.7830.32
11_L29_Q0.7700.31
69_D72_K0.7630.31
77_Q117_L0.7540.31
16_A68_A0.7450.30
22_T63_D0.7300.29
57_V60_N0.7220.29
54_L76_K0.7220.29
66_L70_H0.7150.28
52_K60_N0.7110.28
26_E37_Y0.6940.27
28_E86_Q0.6930.27
77_Q80_E0.6880.27
47_I119_A0.6850.27
37_Y45_N0.6850.27
27_K106_K0.6840.27
101_A105_R0.6810.26
14_L18_S0.6800.26
93_Q112_E0.6750.26
75_A78_K0.6750.26
49_G113_E0.6670.26
66_L84_R0.6620.25
82_A85_Q0.6620.25
13_A45_N0.6620.25
32_L58_R0.6600.25
74_I117_L0.6590.25
9_V60_N0.6590.25
22_T65_Q0.6570.25
84_R113_E0.6510.25
14_L30_N0.6460.25
74_I93_Q0.6450.25
19_Y111_Q0.6430.25
69_D98_D0.6380.24
101_A112_E0.6340.24
110_A117_L0.6340.24
107_L110_A0.6330.24
95_G113_E0.6300.24
110_A113_E0.6270.24
103_R113_E0.6250.24
35_I97_A0.6200.23
10_S36_S0.6150.23
52_K55_S0.6140.23
77_Q111_Q0.6130.23
41_H78_K0.6010.22
11_L14_L0.5920.22
79_D119_A0.5890.22
15_S19_Y0.5820.22
36_S51_N0.5780.21
25_Q46_R0.5770.21
23_L117_L0.5740.21
14_L102_K0.5720.21
12_F17_G0.5720.21
65_Q117_L0.5710.21
105_R111_Q0.5700.21
79_D86_Q0.5700.21
33_K37_Y0.5690.21
35_I54_L0.5590.21
79_D118_E0.5530.20
41_H62_S0.5530.20
26_E117_L0.5470.20
56_E78_K0.5440.20
43_N46_R0.5430.20
8_A45_N0.5410.20
81_V103_R0.5390.20
58_R109_E0.5370.20
12_F18_S0.5370.20
55_S59_A0.5360.20
84_R107_L0.5340.19
42_Q47_I0.5320.19
47_I52_K0.5310.19
77_Q83_E0.5300.19
36_S40_K0.5230.19
49_G109_E0.5210.19
66_L117_L0.5190.19
7_L16_A0.5180.19
31_I52_K0.5160.19
81_V116_K0.5150.19
103_R109_E0.5150.19
60_N64_S0.5150.19
28_E57_V0.5140.19
77_Q81_V0.5130.19
67_R97_A0.5130.19
88_L100_I0.5020.18
98_D108_A0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4cgkA 3 0.5656 88.2 0.874 Contact Map
4b6xA 1 0.4754 86.3 0.877 Contact Map
4q4gX 1 0 82.9 0.883 Contact Map
3layA 5 0.5164 72.3 0.894 Contact Map
3ioxA 1 0.6803 49.3 0.908 Contact Map
4y66A 1 0.9262 34.7 0.916 Contact Map
2pmsC 1 0.7705 32.1 0.917 Contact Map
1gp8A 1 0.3279 27.5 0.92 Contact Map
2lf0A 1 0.4672 23.6 0.922 Contact Map
3mq7A 6 0.7049 20.6 0.925 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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