YGJR - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YGJR - Uncharacterized oxidoreductase YgjR

UniProt:	P42599	Sequences: MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFANDFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQTQLFLSHKINVICEKPLASNLAEVDAAIACARENQVVLFEAFKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYLDGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAQGVVVMDYGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHINTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVIFPADSVKL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12729
Length:	328 (303)
Sequences:	25753 (19052)
Seq/√Len:	1094.5

ECOLI - YGJR YCJS YHHX YDGJ YJHC YCEM
BACSU - YULF NTDC YRBE YFII IOLX IOLW IOLG YTET
HALSA - Q9HQT1
SULSO - Q97UH0 Q97UJ6 Q97UK3 Q97UK0 Q97UJ8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
56_E	82_L	3.097	1.00
77_F	105_A	2.870	1.00
124_A	186_A	2.786	1.00
81_Q	109_C	2.769	1.00
197_S	218_D	2.727	1.00
85_S	109_C	2.692	1.00
144_K	243_E	2.657	1.00
36_L	40_Q	2.641	1.00
3_R	27_K	2.636	1.00
131_L	134_Q	2.585	1.00
104_D	304_R	2.579	1.00
71_S	79_Q	2.419	1.00
77_F	102_E	2.418	1.00
81_Q	85_S	2.396	1.00
133_R	137_P	2.389	1.00
196_K	220_G	2.382	1.00
81_Q	105_A	2.353	1.00
5_A	58_M	2.335	1.00
89_N	116_V	2.304	1.00
215_V	313_I	2.207	1.00
30_A	52_F	2.153	1.00
84_L	115_V	2.137	1.00
75_L	79_Q	2.097	1.00
54_S	57_A	2.069	1.00
288_T	292_E	2.054	1.00
108_A	112_E	2.014	1.00
77_F	81_Q	1.994	1.00
131_L	135_A	1.969	1.00
111_R	301_A	1.953	1.00
14_R	45_D	1.923	1.00
80_T	92_C	1.921	1.00
66_A	286_F	1.902	1.00
50_H	61_S	1.837	1.00
40_Q	44_N	1.833	1.00
84_L	110_A	1.829	1.00
142_L	242_G	1.805	1.00
78_S	82_L	1.804	1.00
71_S	75_L	1.803	1.00
109_C	113_N	1.799	1.00
104_D	108_A	1.779	1.00
85_S	113_N	1.762	1.00
89_N	115_V	1.760	1.00
104_D	308_K	1.753	1.00
67_V	83_F	1.727	1.00
5_A	64_I	1.709	1.00
35_S	38_Q	1.706	1.00
100_L	311_T	1.698	1.00
219_Y	224_V	1.673	1.00
4_F	66_A	1.665	1.00
80_T	106_A	1.650	1.00
202_A	317_T	1.634	1.00
99_N	102_E	1.633	1.00
25_K	291_D	1.631	1.00
23_S	284_E	1.629	1.00
20_A	68_Y	1.620	1.00
194_E	305_I	1.617	1.00
26_Y	287_A	1.613	1.00
60_E	86_H	1.577	1.00
133_R	190_A	1.577	1.00
64_I	88_I	1.567	1.00
120_A	282_E	1.560	1.00
59_A	83_F	1.558	1.00
117_L	300_L	1.553	1.00
196_K	218_D	1.553	1.00
53_T	57_A	1.550	1.00
135_A	141_K	1.517	1.00
305_I	308_K	1.502	1.00
55_L	82_L	1.498	1.00
52_F	61_S	1.488	1.00
132_L	247_L	1.483	1.00
107_I	304_R	1.481	1.00
194_E	220_G	1.475	1.00
107_I	300_L	1.472	1.00
85_S	112_E	1.464	1.00
109_C	112_E	1.459	1.00
41_H	45_D	1.447	1.00
98_S	102_E	1.429	1.00
189_V	194_E	1.425	1.00
57_A	60_E	1.418	1.00
36_L	53_T	1.414	1.00
77_F	106_A	1.411	1.00
116_V	293_H	1.407	1.00
149_Y	239_E	1.394	1.00
146_F	243_E	1.391	1.00
56_E	60_E	1.370	1.00
189_V	305_I	1.359	1.00
97_A	106_A	1.345	1.00
84_L	113_N	1.342	1.00
82_L	85_S	1.341	1.00
97_A	103_V	1.335	1.00
52_F	58_M	1.317	1.00
288_T	294_L	1.316	1.00
103_V	304_R	1.310	1.00
100_L	308_K	1.309	1.00
239_E	248_V	1.295	1.00
100_L	104_D	1.293	1.00
9_T	31_V	1.280	1.00
39_A	51_L	1.278	1.00
142_L	245_G	1.275	1.00
201_T	218_D	1.268	1.00
82_L	86_H	1.266	1.00
285_L	289_L	1.263	1.00
285_L	297_H	1.261	1.00
3_R	29_T	1.255	1.00
32_Y	55_L	1.234	1.00
57_A	61_S	1.214	1.00
195_P	219_Y	1.209	1.00
3_R	65_D	1.208	1.00
69_I	80_T	1.205	1.00
87_K	113_N	1.196	1.00
74_S	172_F	1.195	1.00
287_A	291_D	1.188	1.00
83_F	90_V	1.188	1.00
69_I	79_Q	1.184	1.00
237_A	248_V	1.184	1.00
32_Y	58_M	1.184	1.00
41_H	44_N	1.176	1.00
43_A	51_L	1.171	1.00
107_I	301_A	1.163	1.00
105_A	108_A	1.162	1.00
84_L	109_C	1.159	1.00
189_V	219_Y	1.156	1.00
149_Y	227_Q	1.156	1.00
55_L	79_Q	1.156	1.00
22_E	280_L	1.143	1.00
199_Q	216_V	1.141	1.00
185_L	309_L	1.139	1.00
311_T	315_R	1.133	1.00
284_E	288_T	1.122	1.00
299_G	302_V	1.122	1.00
145_V	240_I	1.115	1.00
169_N	172_F	1.113	1.00
96_L	103_V	1.113	1.00
192_F	223_S	1.109	1.00
91_I	120_A	1.108	1.00
37_E	40_Q	1.107	1.00
55_L	59_A	1.104	1.00
91_I	282_E	1.103	1.00
312_E	315_R	1.093	1.00
4_F	26_Y	1.091	1.00
72_P	75_L	1.089	1.00
148_N	192_F	1.087	1.00
58_M	64_I	1.084	1.00
129_F	190_A	1.082	1.00
189_V	302_V	1.077	1.00
105_A	109_C	1.075	1.00
30_A	64_I	1.075	1.00
107_I	111_R	1.073	1.00
62_D	88_I	1.071	1.00
188_A	224_V	1.066	1.00
30_A	58_M	1.065	1.00
108_A	111_R	1.064	1.00
59_A	82_L	1.057	1.00
103_V	307_A	1.055	1.00
312_E	316_Q	1.052	1.00
63_A	88_I	1.033	1.00
281_Y	284_E	1.009	1.00
142_L	247_L	1.006	1.00
248_V	259_C	1.006	1.00
7_I	79_Q	1.004	1.00
102_E	105_A	1.002	1.00
97_A	102_E	0.987	1.00
101_A	104_D	0.982	1.00
39_A	53_T	0.980	1.00
61_S	64_I	0.979	1.00
92_C	117_L	0.975	1.00
81_Q	106_A	0.975	1.00
89_N	293_H	0.974	1.00
148_N	224_V	0.972	1.00
59_A	86_H	0.971	1.00
18_E	22_E	0.965	1.00
16_F	68_Y	0.955	1.00
124_A	302_V	0.952	1.00
125_C	285_L	0.947	1.00
285_L	294_L	0.938	1.00
132_L	249_I	0.937	1.00
38_Q	41_H	0.937	1.00
89_N	290_V	0.935	1.00
285_L	288_T	0.928	1.00
52_F	57_A	0.921	1.00
80_T	90_V	0.921	1.00
100_L	304_R	0.919	1.00
145_V	242_G	0.916	1.00
39_A	43_A	0.915	1.00
101_A	105_A	0.909	1.00
79_Q	82_L	0.909	1.00
301_A	305_I	0.909	1.00
96_L	300_L	0.908	1.00
314_R	318_G	0.907	1.00
106_A	117_L	0.905	1.00
142_L	145_V	0.905	1.00
280_L	284_E	0.893	1.00
96_L	117_L	0.889	1.00
37_E	41_H	0.888	1.00
308_K	312_E	0.887	1.00
315_R	318_G	0.887	1.00
9_T	33_S	0.884	1.00
195_P	217_M	0.877	1.00
77_F	97_A	0.874	1.00
134_Q	137_P	0.873	1.00
145_V	192_F	0.873	1.00
18_E	45_D	0.873	1.00
40_Q	43_A	0.870	1.00
118_F	286_F	0.866	1.00
239_E	246_S	0.866	1.00
110_A	113_N	0.863	1.00
141_K	262_P	0.860	1.00
75_L	78_S	0.857	1.00
137_P	193_G	0.856	1.00
288_T	293_H	0.854	1.00
40_Q	51_L	0.854	1.00
185_L	310_L	0.850	1.00
122_K	278_T	0.848	1.00
36_L	39_A	0.846	1.00
199_Q	316_Q	0.845	1.00
84_L	90_V	0.845	1.00
31_V	42_F	0.844	1.00
149_Y	225_T	0.841	1.00
214_V	225_T	0.840	1.00
5_A	30_A	0.839	1.00
69_I	83_F	0.839	1.00
33_S	39_A	0.831	1.00
2_I	290_V	0.828	1.00
104_D	107_I	0.827	1.00
170_P	208_G	0.827	1.00
4_F	20_A	0.826	1.00
110_A	117_L	0.822	1.00
92_C	96_L	0.820	1.00
29_T	63_A	0.819	1.00
23_S	26_Y	0.818	1.00
151_Q	237_A	0.815	1.00
68_Y	283_A	0.814	1.00
25_K	284_E	0.812	1.00
80_T	84_L	0.811	1.00
14_R	41_H	0.803	1.00
36_L	51_L	0.803	1.00
169_N	208_G	0.800	1.00
116_V	289_L	0.796	1.00
143_R	245_G	0.795	1.00
130_H	134_Q	0.795	1.00
195_P	309_L	0.794	1.00
148_N	240_I	0.790	1.00
289_L	292_E	0.789	1.00
20_A	26_Y	0.788	1.00
110_A	115_V	0.788	1.00
116_V	290_V	0.788	1.00
150_C	238_S	0.785	1.00
33_S	38_Q	0.780	1.00
20_A	283_A	0.777	1.00
148_N	188_A	0.773	1.00
200_A	313_I	0.771	1.00
262_P	265_S	0.770	1.00
25_K	288_T	0.768	1.00
98_S	173_S	0.767	1.00
289_L	296_D	0.765	1.00
92_C	106_A	0.765	1.00
189_V	306_T	0.764	1.00
16_F	283_A	0.762	1.00
295_V	299_G	0.762	1.00
73_N	179_D	0.757	1.00
244_A	263_R	0.756	1.00
289_L	294_L	0.755	1.00
237_A	250_E	0.755	1.00
27_K	49_E	0.754	1.00
110_A	300_L	0.754	1.00
5_A	32_Y	0.753	1.00
6_V	17_V	0.751	1.00
201_T	216_V	0.751	1.00
3_R	64_I	0.747	1.00
279_M	282_E	0.746	1.00
103_V	107_I	0.746	1.00
7_I	55_L	0.745	1.00
217_M	224_V	0.744	1.00
121_F	182_F	0.741	1.00
2_I	66_A	0.740	1.00
12_I	70_A	0.740	1.00
143_R	242_G	0.740	1.00
13_T	70_A	0.739	1.00
43_A	48_V	0.737	1.00
181_G	228_H	0.737	1.00
118_F	289_L	0.736	1.00
136_L	242_G	0.735	1.00
12_I	16_F	0.731	1.00
119_E	303_S	0.730	1.00
84_L	117_L	0.728	1.00
13_T	18_E	0.727	1.00
7_I	71_S	0.726	1.00
50_H	63_A	0.726	1.00
304_R	308_K	0.725	1.00
150_C	184_C	0.724	1.00
176_S	228_H	0.723	1.00
29_T	64_I	0.716	1.00
42_F	45_D	0.712	1.00
96_L	119_E	0.712	1.00
170_P	318_G	0.711	1.00
130_H	281_Y	0.709	1.00
66_A	89_N	0.709	1.00
144_K	244_A	0.706	1.00
175_G	210_D	0.705	1.00
151_Q	227_Q	0.699	1.00
210_D	314_R	0.698	1.00
153_S	227_Q	0.695	1.00
61_S	88_I	0.694	1.00
195_P	220_G	0.692	1.00
182_F	306_T	0.692	1.00
177_I	310_L	0.690	1.00
203_S	218_D	0.690	1.00
76_H	92_C	0.689	1.00
192_F	219_Y	0.688	1.00
177_I	213_G	0.687	1.00
7_I	32_Y	0.685	1.00
123_T	126_L	0.685	1.00
211_A	231_V	0.683	1.00
5_A	67_V	0.681	1.00
194_E	308_K	0.681	1.00
17_V	28_L	0.679	1.00
286_F	290_V	0.678	1.00
12_I	279_M	0.677	1.00
29_T	50_H	0.677	1.00
200_A	215_V	0.677	1.00
81_Q	84_L	0.673	1.00
29_T	61_S	0.670	1.00
302_V	305_I	0.668	1.00
197_S	201_T	0.667	1.00
133_R	191_L	0.666	1.00
2_I	291_D	0.666	1.00
129_F	187_S	0.665	1.00
215_V	226_L	0.665	1.00
4_F	287_A	0.664	1.00
241_Q	246_S	0.663	1.00
77_F	109_C	0.662	1.00
87_K	115_V	0.660	1.00
78_S	105_A	0.655	1.00
80_T	117_L	0.654	1.00
188_A	219_Y	0.653	1.00
186_A	306_T	0.651	1.00
91_I	118_F	0.648	1.00
84_L	106_A	0.648	1.00
300_L	303_S	0.645	1.00
88_I	115_V	0.643	1.00
150_C	188_A	0.641	1.00
130_H	297_H	0.640	1.00
35_S	40_Q	0.640	1.00
174_N	178_M	0.639	1.00
92_C	119_E	0.638	1.00
94_K	183_Y	0.636	1.00
144_K	221_D	0.636	1.00
3_R	63_A	0.636	1.00
179_D	230_K	0.634	1.00
181_G	184_C	0.633	1.00
200_A	317_T	0.632	1.00
307_A	311_T	0.630	1.00
189_V	309_L	0.626	1.00
147_F	241_Q	0.625	1.00
58_M	61_S	0.625	1.00
124_A	190_A	0.625	1.00
9_T	39_A	0.625	1.00
14_R	18_E	0.624	1.00
258_V	261_V	0.620	1.00
191_L	240_I	0.618	1.00
121_F	306_T	0.617	1.00
121_F	186_A	0.617	1.00
116_V	295_V	0.615	1.00
229_S	232_S	0.615	1.00
116_V	296_D	0.613	1.00
11_W	15_Q	0.613	1.00
23_S	287_A	0.608	1.00
200_A	213_G	0.607	1.00
136_L	240_I	0.606	1.00
130_H	190_A	0.604	1.00
67_V	88_I	0.603	1.00
66_A	290_V	0.602	1.00
205_L	211_A	0.597	1.00
185_L	313_I	0.597	1.00
42_F	46_F	0.597	1.00
186_A	190_A	0.595	1.00
270_L	273_P	0.592	1.00
14_R	38_Q	0.590	1.00
25_K	287_A	0.586	1.00
4_F	68_Y	0.584	1.00
56_E	78_S	0.583	1.00
285_L	296_D	0.582	1.00
122_K	279_M	0.582	1.00
9_T	42_F	0.581	1.00
199_Q	218_D	0.581	1.00
14_R	46_F	0.579	1.00
12_I	93_E	0.576	1.00
141_K	144_K	0.574	1.00
55_L	83_F	0.573	1.00
152_Y	180_I	0.571	1.00
216_V	225_T	0.569	1.00
132_L	191_L	0.568	1.00
202_A	213_G	0.568	1.00
68_Y	91_I	0.567	1.00
118_F	285_L	0.565	1.00
26_Y	66_A	0.560	1.00
17_V	42_F	0.559	1.00
262_P	266_Q	0.559	1.00
14_R	42_F	0.558	1.00
135_A	260_F	0.555	1.00
167_T	179_D	0.555	1.00
52_F	62_D	0.550	1.00
23_S	280_L	0.548	1.00
178_M	311_T	0.547	1.00
123_T	186_A	0.546	1.00
277_N	280_L	0.546	1.00
78_S	81_Q	0.545	1.00
10_N	70_A	0.544	1.00
212_Q	229_S	0.542	1.00
93_E	120_A	0.541	1.00
140_G	144_K	0.541	1.00
32_Y	52_F	0.540	1.00
74_S	98_S	0.540	1.00
44_N	51_L	0.538	1.00
80_T	110_A	0.537	1.00
94_K	179_D	0.536	1.00
171_A	208_G	0.534	1.00
34_R	71_S	0.533	1.00
183_Y	186_A	0.533	1.00
154_S	180_I	0.533	1.00
69_I	76_H	0.533	1.00
188_A	226_L	0.532	1.00
107_I	110_A	0.532	1.00
253_S	257_K	0.531	1.00
288_T	291_D	0.529	1.00
118_F	282_E	0.529	1.00
147_F	225_T	0.529	1.00
306_T	310_L	0.527	1.00
65_D	291_D	0.526	1.00
276_I	280_L	0.526	1.00
177_I	215_V	0.524	1.00
70_A	93_E	0.523	1.00
214_V	227_Q	0.521	1.00
147_F	212_Q	0.520	1.00
136_L	191_L	0.519	1.00
13_T	42_F	0.519	1.00
56_E	86_H	0.517	1.00
71_S	76_H	0.516	1.00
166_N	169_N	0.515	1.00
2_I	26_Y	0.514	1.00
173_S	209_V	0.512	1.00
217_M	226_L	0.511	1.00
212_Q	227_Q	0.511	1.00
18_E	21_H	0.509	1.00
85_S	105_A	0.507	1.00
99_N	311_T	0.507	1.00
6_V	28_L	0.505	1.00
127_P	281_Y	0.504	1.00
310_L	314_R	0.503	1.00
6_V	68_Y	0.503	1.00
219_Y	223_S	0.502	1.00
16_F	20_A	0.501	1.00
242_G	247_L	0.500	1.00
147_F	227_Q	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1zh8A	2	0.9604	100	0.163	Contact Map
1h6dA	8	0.9939	100	0.164	Contact Map
2nvwA	3	0.9604	100	0.172	Contact Map
3dtyA	4	0.9512	100	0.177	Contact Map
3db2A	2	0.9848	100	0.185	Contact Map
3v5nA	4	0.9268	100	0.187	Contact Map
4gqaA	4	0.9939	100	0.189	Contact Map
4hadA	4	0.936	100	0.197	Contact Map
3btvA	2	0.9604	100	0.198	Contact Map
3euwA	4	0.9695	100	0.201	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0092 seconds.