GREMLIN Database
YGJP - Uncharacterized protein YgjP
UniProt: P42597 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12727
Length: 167 (159)
Sequences: 399 (228)
Seq/√Len: 18.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
116_R143_E5.0081.00
22_I162_L3.3911.00
156_W160_L3.2010.99
75_H79_N3.1630.99
143_E149_L3.0450.99
120_V142_M2.8500.98
107_F118_I2.7550.98
86_A129_K2.7310.98
35_Y152_D2.6020.97
19_R23_N2.5880.97
88_S95_L2.5160.96
61_N64_P2.3180.94
7_L158_T2.2950.94
9_G15_L2.2880.94
128_E132_N2.2770.94
76_V79_N2.2330.93
114_F118_I2.2250.93
86_A99_V2.1770.92
137_Q141_H2.0820.90
74_I83_L2.0200.89
61_N137_Q2.0180.89
99_V129_K1.9940.88
20_T70_Y1.8500.84
107_F114_F1.7780.82
43_T48_W1.7470.80
61_N127_K1.7210.79
5_T158_T1.7030.79
74_I129_K1.6410.76
59_L114_F1.6170.75
28_G159_Q1.5910.74
14_L155_L1.5800.73
51_T83_L1.5370.71
116_R149_L1.5090.69
75_H78_K1.5030.69
89_R95_L1.4620.67
74_I99_V1.4490.66
91_Q98_K1.4390.66
14_L151_F1.4180.64
156_W159_Q1.4160.64
86_A97_A1.3850.63
42_A99_V1.3740.62
34_R59_L1.3700.62
118_I156_W1.3580.61
51_T132_N1.3460.60
30_V151_F1.3260.59
67_K100_E1.3190.59
113_P149_L1.3120.58
51_T119_V1.3120.58
30_V152_D1.3080.58
48_W143_E1.3030.58
67_K102_R1.3030.58
45_K49_Q1.2890.57
22_I25_Q1.2870.57
130_E134_A1.2780.56
18_V155_L1.2650.55
12_E16_S1.2610.55
42_A160_L1.2580.55
106_V160_L1.2400.54
52_Q61_N1.2160.52
32_A42_A1.2090.52
62_A132_N1.1880.51
129_K132_N1.1790.50
56_N83_L1.0920.45
38_T42_A1.0800.44
87_V100_E1.0780.44
45_K73_K1.0750.44
14_L98_K1.0610.43
59_L75_H1.0470.42
32_A38_T1.0380.42
84_H161_S1.0310.41
89_R97_A1.0000.39
114_F153_T0.9940.39
103_V142_M0.9870.39
4_L162_L0.9770.38
70_Y140_C0.9700.38
70_Y107_F0.9380.36
110_A153_T0.9350.36
56_N74_I0.9280.35
107_F144_P0.9270.35
31_L44_D0.9180.35
73_K76_V0.9170.35
120_V134_A0.9050.34
59_L83_L0.9040.34
31_L54_L0.8950.33
80_A84_H0.8900.33
19_R40_D0.8860.33
51_T69_M0.8740.32
119_V141_H0.8730.32
36_P93_G0.8640.32
60_R80_A0.8620.32
66_N98_K0.8590.31
26_R29_D0.8570.31
24_E130_E0.8500.31
22_I109_N0.8450.31
40_D62_A0.8450.31
25_Q159_Q0.8420.30
50_Y112_E0.8400.30
12_E161_S0.8300.30
18_V25_Q0.8290.30
31_L118_I0.8260.30
42_A56_N0.8250.30
85_T95_L0.8230.29
33_K50_Y0.8180.29
16_S45_K0.8160.29
50_Y116_R0.8120.29
41_Y83_L0.8110.29
49_Q53_D0.8030.28
75_H133_K0.7990.28
70_Y110_A0.7950.28
107_F153_T0.7930.28
83_L126_L0.7930.28
31_L114_F0.7900.28
74_I78_K0.7790.27
46_A98_K0.7780.27
15_L158_T0.7770.27
32_A37_G0.7770.27
129_K137_Q0.7740.27
38_T60_R0.7720.27
57_Q137_Q0.7720.27
14_L72_N0.7640.27
77_L144_P0.7610.26
67_K87_V0.7550.26
61_N91_Q0.7440.26
74_I80_A0.7440.26
28_G31_L0.7400.25
34_R72_N0.7370.25
62_A84_H0.7310.25
61_N160_L0.7290.25
77_L116_R0.7290.25
30_V75_H0.7250.25
66_N88_S0.7240.25
25_Q137_Q0.7200.24
52_Q126_L0.7160.24
46_A106_V0.7060.24
22_I155_L0.7050.24
9_G91_Q0.7030.24
32_A112_E0.7030.24
57_Q108_R0.7010.24
44_D137_Q0.6990.24
9_G133_K0.6980.23
89_R98_K0.6960.23
22_I80_A0.6950.23
107_F159_Q0.6940.23
78_K133_K0.6940.23
23_N28_G0.6870.23
52_Q108_R0.6850.23
153_T156_W0.6830.23
18_V22_I0.6800.23
91_Q118_I0.6760.23
34_R94_K0.6730.22
48_W68_V0.6660.22
76_V80_A0.6650.22
52_Q56_N0.6650.22
57_Q141_H0.6650.22
100_E126_L0.6650.22
54_L127_K0.6630.22
28_G85_T0.6530.22
87_V102_R0.6510.21
66_N91_Q0.6480.21
87_V91_Q0.6480.21
48_W116_R0.6460.21
112_E149_L0.6450.21
105_T140_C0.6380.21
102_R151_F0.6350.21
14_L103_V0.6340.21
86_A132_N0.6320.21
73_K94_K0.6270.20
71_D118_I0.6260.20
72_N75_H0.6220.20
72_N137_Q0.6220.20
26_R105_T0.6220.20
137_Q140_C0.6210.20
30_V43_T0.6200.20
26_R141_H0.6150.20
54_L123_L0.6130.20
58_F77_L0.6130.20
41_Y44_D0.6120.20
44_D97_A0.6100.20
8_Q103_V0.6050.20
5_T113_P0.6040.20
102_R126_L0.6020.20
25_Q57_Q0.5980.19
42_A159_Q0.5960.19
104_A109_N0.5930.19
63_P161_S0.5920.19
37_G50_Y0.5910.19
62_A86_A0.5910.19
16_S19_R0.5900.19
48_W61_N0.5880.19
89_R102_R0.5840.19
69_M100_E0.5780.19
70_Y162_L0.5730.18
58_F143_E0.5720.18
75_H93_G0.5670.18
12_E158_T0.5650.18
49_Q52_Q0.5650.18
8_Q93_G0.5630.18
28_G126_L0.5630.18
63_P130_E0.5610.18
56_N66_N0.5600.18
78_K104_A0.5590.18
20_T112_E0.5580.18
68_V101_I0.5580.18
7_L71_D0.5580.18
106_V110_A0.5560.18
9_G43_T0.5560.18
17_Q116_R0.5560.18
56_N94_K0.5540.18
5_T88_S0.5530.18
12_E145_Q0.5510.18
153_T159_Q0.5500.18
31_L132_N0.5500.18
110_A162_L0.5490.18
99_V161_S0.5480.17
68_V97_A0.5480.17
118_I153_T0.5460.17
16_S29_D0.5440.17
34_R37_G0.5410.17
87_V98_K0.5410.17
30_V143_E0.5370.17
29_D33_K0.5360.17
27_L158_T0.5350.17
67_K71_D0.5330.17
75_H161_S0.5320.17
143_E159_Q0.5280.17
61_N66_N0.5260.17
66_N87_V0.5240.17
65_I69_M0.5240.17
76_V107_F0.5230.17
66_N99_V0.5200.17
44_D72_N0.5190.16
7_L157_L0.5150.16
69_M102_R0.5150.16
74_I112_E0.5110.16
13_Q94_K0.5030.16
69_M103_V0.5020.16
73_K161_S0.5010.16
117_M157_L0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4qhjA 2 0.5629 99.1 0.856 Contact Map
4jixA 2 0.6467 99 0.864 Contact Map
4jiuA 1 0.5749 98.8 0.873 Contact Map
3cqbA 4 0.5988 93.3 0.936 Contact Map
3c37A 1 0.7605 83.5 0.947 Contact Map
2lh0A 2 0.3772 25.3 0.965 Contact Map
3thxB 1 0.3114 9.2 0.971 Contact Map
4il3A 1 0.8204 7.7 0.972 Contact Map
3fxhA 2 0.5569 7.4 0.972 Contact Map
3dteA 2 0.7006 6.1 0.973 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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