GREMLIN Database
YGJH - tRNA-binding protein YgjH
UniProt: P42589 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12719
Length: 110 (106)
Sequences: 2672 (1481)
Seq/√Len: 143.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_R50_V3.5181.00
18_K62_T3.2721.00
21_E35_Q2.9911.00
54_S57_E2.7611.00
28_A75_R2.4641.00
8_D11_R2.3401.00
14_M64_V2.2781.00
18_K105_A2.2231.00
23_K33_I2.1631.00
45_T81_C2.0881.00
17_G36_V2.0791.00
45_T65_V1.9561.00
25_H33_I1.9141.00
46_V77_E1.8871.00
38_V65_V1.7781.00
21_E59_M1.7571.00
12_L66_L1.7231.00
46_V74_M1.7071.00
44_Q77_E1.6701.00
5_A8_D1.6341.00
29_D75_R1.6341.00
15_R67_C1.6141.00
3_T70_Q1.6081.00
61_K98_T1.5881.00
35_Q44_Q1.5731.00
13_E108_R1.5701.00
17_G65_V1.5511.00
19_I63_V1.4591.00
35_Q42_T1.4531.00
62_T102_M1.4531.00
34_V85_C1.4431.00
4_V12_L1.4421.00
32_Y55_E1.3841.00
33_I44_Q1.3671.00
37_D105_A1.3131.00
88_T93_E1.2381.00
73_K78_T1.2361.00
29_D51_P1.2211.00
87_E91_G1.2111.00
33_I77_E1.2111.00
24_R55_E1.1781.00
14_M66_L1.1691.00
20_V37_D1.1480.99
38_V41_K1.1440.99
16_V62_T1.1410.99
22_V34_V1.1210.99
22_V55_E1.1090.99
18_K37_D1.0960.99
25_H77_E1.0920.99
6_Y10_A1.0790.99
64_V97_L1.0640.99
46_V72_A1.0610.99
5_A70_Q1.0580.99
16_V64_V1.0480.99
38_V67_C1.0290.99
34_V47_T1.0070.99
62_T105_A1.0070.99
34_V83_L1.0060.99
22_V32_Y0.9990.99
52_Y94_S0.9380.98
98_T101_R0.9260.98
86_A103_M0.9140.97
36_V63_V0.8940.97
32_Y50_V0.8900.97
47_T85_C0.8750.97
88_T91_G0.8730.97
45_T83_L0.8730.97
63_V83_L0.8670.96
43_L67_C0.8640.96
104_P107_V0.8620.96
34_V58_L0.8450.96
27_N75_R0.8420.96
23_K35_Q0.8390.96
37_D42_T0.8210.95
90_D93_E0.8160.95
17_G38_V0.8080.95
48_S74_M0.8070.95
36_V45_T0.8060.95
28_A50_V0.7980.94
61_K100_E0.7960.94
7_A10_A0.7830.94
22_V59_M0.7820.94
86_A107_V0.7660.93
18_K102_M0.7550.93
69_L82_M0.7520.92
25_H28_A0.7370.92
85_C96_L0.7290.91
64_V109_V0.7170.91
55_E59_M0.7110.90
36_V65_V0.7080.90
95_V101_R0.6990.89
53_Y96_L0.6960.89
103_M107_V0.6900.89
29_D73_K0.6810.88
95_V103_M0.6790.88
19_I58_L0.6790.88
48_S82_M0.6790.88
15_R108_R0.6760.88
16_V99_P0.6710.87
55_E58_L0.6690.87
31_L48_S0.6670.87
43_L81_C0.6660.87
6_Y72_A0.6580.86
29_D50_V0.6540.86
95_V100_E0.6470.85
20_V42_T0.6460.85
4_V66_L0.6460.85
53_Y58_L0.6460.85
95_V99_P0.6450.85
14_M67_C0.6290.84
30_K51_P0.6240.83
58_L96_L0.6170.83
99_P103_M0.6160.83
56_E59_M0.6040.81
54_S58_L0.6030.81
23_K26_E0.6000.81
38_V105_A0.5990.81
26_E29_D0.5990.81
72_A75_R0.5890.80
37_D41_K0.5780.78
84_L109_V0.5770.78
31_L82_M0.5760.78
93_E101_R0.5750.78
62_T104_P0.5740.78
83_L96_L0.5740.78
47_T83_L0.5670.77
19_I96_L0.5600.76
22_V47_T0.5600.76
52_Y87_E0.5580.76
32_Y49_L0.5580.76
37_D40_Q0.5570.76
14_M84_L0.5510.75
87_E94_S0.5490.75
62_T98_T0.5480.75
97_L109_V0.5460.74
62_T99_P0.5440.74
76_G82_M0.5440.74
8_D12_L0.5390.74
70_Q73_K0.5390.74
62_T107_V0.5380.73
20_V35_Q0.5380.73
96_L99_P0.5330.73
65_V83_L0.5280.72
95_V98_T0.5260.72
19_I22_V0.5240.71
25_H46_V0.5220.71
32_Y81_C0.5150.70
24_R54_S0.5150.70
28_A32_Y0.5140.70
13_E67_C0.5140.70
97_L100_E0.5110.70
33_I46_V0.5110.70
61_K96_L0.5100.69
17_G63_V0.5100.69
27_N76_G0.5090.69
25_H75_R0.5090.69
46_V76_G0.5020.68
19_I53_Y0.5000.68
16_V103_M0.5000.68
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ersX 2 1 100 0.189 Contact Map
2cwpA 2 0.9818 100 0.203 Contact Map
1mkhA 2 0.9636 100 0.227 Contact Map
1gd7A 2 0.9727 100 0.237 Contact Map
2q2iA 2 0.9909 100 0.239 Contact Map
1pybA 2 0.9727 100 0.24 Contact Map
2nzhA 5 0.9727 100 0.242 Contact Map
3g48A 2 0.9818 100 0.247 Contact Map
2q2hA 2 0.9909 100 0.249 Contact Map
1rqgA 2 0 100 0.258 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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