QSEC - ECOLI - GREMLIN Contacts

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QSEC - Sensor protein QseC

UniProt:	P40719	Sequences: MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELFDTQLMLFAKRLSTLDLNEINAADRMAQTPNRLKHGHVDDDALTFAIFTHDGRMVLNDGDNGEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIVAGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRPLVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKIDVRLTLNAHSIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADNFIVRDNGPGVTPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSW	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13027
Length:	449 (422)
Sequences:	46648 (39809)
Seq/√Len:	1937.9

ECOLI - QSEC BARA CUSS YEDV GLRK BAES PHOQ CREC TORS CPXA ATOS ENVZ RCSD RSTB RCSC ZRAS EVGS DCUS DPIB NARX ARCB NARQ BASS KDPD PHOR YPDA
BACSU - YCLK YYCG CSSS YKOH RESE YVRG PHOR DCTS YVCQ MALK KIND YRKQ CITS KINB YXDK YESM YCBM KINE BCES KINA YBDK GLNK KINC LYTS LIAS YWPD COMP
HALSA - Q9HQ15 Q9HQG5 Q9HQ16 Q9HQE9 Q9HRE4 O51970 BAT Q9HRG1 Q9HR10 Q9HNM2 Q9HQB9 Q9HNA6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
386_R	444_E	3.964	1.00
387_D	391_G	3.914	1.00
423_Q	427_K	3.739	1.00
311_I	348_G	3.709	1.00
434_E	446_K	3.302	1.00
259_T	279_L	3.221	1.00
384_I	444_E	2.994	1.00
377_T	384_I	2.940	1.00
397_L	437_N	2.931	1.00
336_R	375_D	2.882	1.00
368_S	388_N	2.813	1.00
348_G	429_H	2.771	1.00
263_Q	280_H	2.727	1.00
310_E	347_T	2.718	1.00
336_R	373_V	2.706	1.00
338_T	377_T	2.633	1.00
256_K	284_D	2.607	1.00
375_D	386_R	2.579	1.00
373_V	388_N	2.576	1.00
426_A	431_M	2.573	1.00
422_V	433_V	2.570	1.00
438_A	441_G	2.563	1.00
263_Q	277_L	2.561	1.00
393_T	396_A	2.535	1.00
384_I	446_K	2.517	1.00
310_E	345_K	2.510	1.00
356_L	426_A	2.487	1.00
392_V	400_I	2.420	1.00
435_F	445_A	2.405	1.00
377_T	386_R	2.360	1.00
401_G	433_V	2.345	1.00
436_G	444_E	2.344	1.00
379_N	384_I	2.338	1.00
312_P	315_D	2.331	1.00
436_G	446_K	2.280	1.00
397_L	435_F	2.245	1.00
396_A	399_R	2.228	1.00
319_S	354_S	2.210	1.00
338_T	375_D	2.160	1.00
309_A	350_P	2.155	1.00
334_D	373_V	2.123	1.00
214_S	217_R	2.108	1.00
256_K	283_I	2.100	1.00
324_I	358_R	2.100	1.00
234_M	237_E	2.068	1.00
256_K	287_T	2.040	1.00
399_R	402_E	2.032	1.00
437_N	443_F	2.021	1.00
239_R	243_D	2.009	1.00
426_A	447_V	2.007	1.00
308_V	347_T	1.983	1.00
356_L	425_I	1.980	1.00
348_G	353_L	1.967	1.00
394_P	397_L	1.922	1.00
287_T	291_D	1.914	1.00
212_V	217_R	1.908	1.00
368_S	372_S	1.904	1.00
328_A	365_V	1.882	1.00
425_I	429_H	1.853	1.00
30_F	34_K	1.845	1.00
356_L	422_V	1.843	1.00
399_R	405_Y	1.833	1.00
396_A	405_Y	1.824	1.00
362_D	366_R	1.805	1.00
372_S	388_N	1.799	1.00
235_V	239_R	1.788	1.00
392_V	396_A	1.765	1.00
260_E	280_H	1.763	1.00
349_Q	352_L	1.749	1.00
198_M	202_D	1.736	1.00
357_V	383_F	1.720	1.00
226_L	230_T	1.701	1.00
427_K	432_N	1.695	1.00
263_Q	273_K	1.673	1.00
314_E	318_Q	1.662	1.00
259_T	280_H	1.655	1.00
383_F	447_V	1.644	1.00
396_A	407_P	1.641	1.00
220_V	224_N	1.609	1.00
401_G	435_F	1.599	1.00
359_N	422_V	1.585	1.00
213_P	217_R	1.574	1.00
280_H	284_D	1.562	1.00
92_T	96_R	1.537	1.00
193_A	218_P	1.532	1.00
375_D	388_N	1.521	1.00
258_Q	275_A	1.520	1.00
262_A	276_L	1.495	1.00
227_F	230_T	1.494	1.00
323_D	354_S	1.486	1.00
255_L	283_I	1.471	1.00
352_L	355_L	1.467	1.00
232_A	236_R	1.458	1.00
319_S	350_P	1.457	1.00
437_N	441_G	1.456	1.00
392_V	443_F	1.451	1.00
193_A	197_R	1.450	1.00
402_E	405_Y	1.444	1.00
312_P	343_S	1.441	1.00
368_S	374_V	1.438	1.00
237_E	241_T	1.437	1.00
233_M	237_E	1.433	1.00
393_T	439_E	1.427	1.00
426_A	433_V	1.422	1.00
397_L	401_G	1.419	1.00
352_L	428_L	1.413	1.00
224_N	227_F	1.410	1.00
216_V	220_V	1.406	1.00
350_P	354_S	1.404	1.00
255_L	279_L	1.394	1.00
424_R	427_K	1.388	1.00
325_Y	329_Q	1.383	1.00
231_H	235_V	1.381	1.00
312_P	345_K	1.376	1.00
256_K	280_H	1.370	1.00
247_E	355_L	1.358	1.00
254_A	258_Q	1.354	1.00
321_V	337_L	1.346	1.00
318_Q	337_L	1.344	1.00
254_A	282_G	1.334	1.00
178_M	182_L	1.326	1.00
437_N	440_Q	1.320	1.00
314_E	378_L	1.310	1.00
265_S	272_R	1.298	1.00
262_A	272_R	1.277	1.00
243_D	403_R	1.274	1.00
268_D	272_R	1.268	1.00
314_E	339_L	1.263	1.00
356_L	447_V	1.259	1.00
352_L	425_I	1.259	1.00
367_Y	406_R	1.257	1.00
316_L	320_S	1.251	1.00
259_T	283_I	1.245	1.00
190_N	193_A	1.237	1.00
223_L	226_L	1.236	1.00
327_T	330_Q	1.233	1.00
258_Q	278_Q	1.228	1.00
288_R	351_L	1.224	1.00
400_I	435_F	1.203	1.00
320_S	358_R	1.201	1.00
240_F	244_A	1.197	1.00
277_L	281_S	1.196	1.00
387_D	442_G	1.193	1.00
401_G	423_Q	1.186	1.00
386_R	438_A	1.184	1.00
320_S	324_I	1.183	1.00
198_M	205_K	1.183	1.00
406_R	412_A	1.181	1.00
31_V	35_Q	1.175	1.00
339_L	378_L	1.174	1.00
314_E	343_S	1.172	1.00
182_L	186_L	1.162	1.00
157_L	161_A	1.157	1.00
161_A	165_I	1.147	1.00
259_T	263_Q	1.136	1.00
185_E	188_P	1.136	1.00
257_V	261_V	1.132	1.00
359_N	362_D	1.129	1.00
62_E	66_A	1.121	1.00
268_D	271_A	1.119	1.00
291_D	295_T	1.115	1.00
410_Q	413_T	1.112	1.00
254_A	257_V	1.111	1.00
394_P	437_N	1.110	1.00
317_L	378_L	1.108	1.00
306_Q	349_Q	1.104	1.00
202_D	205_K	1.100	1.00
37_T	41_D	1.098	1.00
231_H	234_M	1.096	1.00
259_T	276_L	1.095	1.00
308_V	429_H	1.093	1.00
249_R	291_D	1.090	1.00
267_D	272_R	1.086	1.00
320_S	354_S	1.083	1.00
401_G	445_A	1.074	1.00
233_M	236_R	1.072	1.00
435_F	443_F	1.070	1.00
392_V	397_L	1.069	1.00
274_K	278_Q	1.050	1.00
29_S	33_W	1.047	1.00
353_L	429_H	1.047	1.00
273_K	277_L	1.043	1.00
195_A	207_L	1.040	1.00
364_A	374_V	1.039	1.00
217_R	220_V	1.039	1.00
206_P	228_A	1.030	1.00
196_L	223_L	1.029	1.00
315_D	319_S	1.028	1.00
216_V	219_L	1.027	1.00
197_R	218_P	1.024	1.00
222_S	225_Q	1.022	1.00
311_I	316_L	1.021	1.00
354_S	358_R	1.020	1.00
340_N	379_N	1.015	1.00
10_R	183_G	1.013	1.00
256_K	260_E	1.013	1.00
33_W	160_V	1.010	1.00
91_F	97_M	1.008	1.00
344_I	380_A	1.006	1.00
333_I	368_S	1.004	1.00
357_V	385_V	1.000	1.00
49_M	53_K	0.995	1.00
360_L	422_V	0.989	1.00
392_V	435_F	0.989	1.00
323_D	358_R	0.984	1.00
292_Q	352_L	0.980	1.00
403_R	424_R	0.976	1.00
360_L	433_V	0.974	1.00
294_L	297_S	0.972	1.00
183_G	187_A	0.970	1.00
208_N	224_N	0.967	1.00
313_L	383_F	0.965	1.00
209_A	212_V	0.964	1.00
357_V	361_L	0.960	1.00
239_R	403_R	0.958	1.00
234_M	238_R	0.940	1.00
196_L	222_S	0.939	1.00
130_R	135_T	0.936	1.00
45_D	49_M	0.936	1.00
175_L	179_M	0.936	1.00
176_I	180_V	0.934	1.00
324_I	361_L	0.934	1.00
282_G	285_R	0.932	1.00
316_L	348_G	0.929	1.00
321_V	325_Y	0.928	1.00
358_R	362_D	0.928	1.00
288_R	292_Q	0.926	1.00
417_L	421_I	0.923	1.00
188_P	192_L	0.922	1.00
281_S	319_S	0.919	1.00
193_A	222_S	0.916	1.00
266_D	272_R	0.913	1.00
247_E	359_N	0.911	1.00
278_Q	282_G	0.909	1.00
320_S	323_D	0.908	1.00
392_V	398_A	0.905	1.00
232_A	235_V	0.904	1.00
12_R	214_S	0.902	1.00
400_I	445_A	0.893	1.00
48_L	52_A	0.893	1.00
189_L	193_A	0.892	1.00
87_T	100_N	0.891	1.00
367_Y	390_P	0.891	1.00
270_Q	273_K	0.890	1.00
206_P	224_N	0.886	1.00
250_S	254_A	0.884	1.00
220_V	223_L	0.882	1.00
41_D	45_D	0.881	1.00
332_K	371_G	0.881	1.00
422_V	426_A	0.881	1.00
279_L	283_I	0.880	1.00
225_Q	229_R	0.880	1.00
34_K	37_T	0.879	1.00
227_F	231_H	0.877	1.00
312_P	344_I	0.877	1.00
324_I	362_D	0.876	1.00
246_H	250_S	0.874	1.00
51_F	54_R	0.874	1.00
217_R	221_E	0.874	1.00
351_L	354_S	0.873	1.00
197_R	222_S	0.873	1.00
307_D	349_Q	0.872	1.00
241_T	244_A	0.872	1.00
308_V	430_G	0.871	1.00
89_A	144_V	0.869	1.00
117_F	122_L	0.869	1.00
361_L	376_V	0.866	1.00
356_L	429_H	0.864	1.00
43_L	47_Q	0.864	1.00
52_A	56_S	0.863	1.00
431_M	447_V	0.862	1.00
334_D	337_L	0.861	1.00
44_F	47_Q	0.861	1.00
318_Q	322_M	0.860	1.00
209_A	221_E	0.855	1.00
327_T	362_D	0.854	1.00
34_K	38_D	0.852	1.00
179_M	183_G	0.851	1.00
247_E	251_P	0.850	1.00
180_V	184_R	0.848	1.00
142_R	146_G	0.848	1.00
317_L	357_V	0.845	1.00
62_E	65_A	0.845	1.00
63_I	67_D	0.843	1.00
283_I	287_T	0.843	1.00
47_Q	50_L	0.843	1.00
223_L	227_F	0.840	1.00
387_D	443_F	0.836	1.00
360_L	445_A	0.831	1.00
277_L	280_H	0.829	1.00
423_Q	432_N	0.829	1.00
424_R	428_L	0.828	1.00
274_K	277_L	0.828	1.00
160_V	164_L	0.827	1.00
308_V	348_G	0.823	1.00
161_A	164_L	0.821	1.00
190_N	194_L	0.821	1.00
182_L	185_E	0.817	1.00
360_L	426_A	0.816	1.00
392_V	437_N	0.813	1.00
86_L	89_A	0.812	1.00
64_N	67_D	0.809	1.00
292_Q	355_L	0.805	1.00
199_R	203_S	0.805	1.00
206_P	227_F	0.802	1.00
261_V	265_S	0.801	1.00
408_P	411_T	0.798	1.00
46_T	49_M	0.795	1.00
43_L	46_T	0.795	1.00
138_D	141_Y	0.793	1.00
295_T	355_L	0.792	1.00
393_T	407_P	0.790	1.00
355_L	425_I	0.789	1.00
406_R	414_G	0.789	1.00
360_L	447_V	0.788	1.00
320_S	361_L	0.788	1.00
89_A	97_M	0.788	1.00
200_D	204_E	0.787	1.00
39_N	43_L	0.786	1.00
195_A	205_K	0.784	1.00
149_W	153_E	0.784	1.00
207_L	224_N	0.783	1.00
321_V	335_V	0.781	1.00
333_I	337_L	0.780	1.00
248_L	286_A	0.777	1.00
56_S	60_L	0.776	1.00
332_K	370_Q	0.773	1.00
394_P	398_A	0.770	1.00
212_V	220_V	0.769	1.00
258_Q	282_G	0.769	1.00
249_R	287_T	0.768	1.00
253_T	257_V	0.768	1.00
52_A	55_L	0.768	1.00
42_E	45_D	0.766	1.00
284_D	287_T	0.765	1.00
296_L	420_S	0.764	1.00
285_R	354_S	0.763	1.00
47_Q	51_F	0.763	1.00
278_Q	281_S	0.761	1.00
199_R	202_D	0.760	1.00
184_R	187_A	0.760	1.00
194_L	198_M	0.760	1.00
67_D	71_Q	0.759	1.00
229_R	232_A	0.758	1.00
191_K	195_A	0.757	1.00
311_I	350_P	0.757	1.00
135_T	142_R	0.756	1.00
322_M	325_Y	0.754	1.00
252_L	290_V	0.754	1.00
197_R	200_D	0.753	1.00
26_L	30_F	0.753	1.00
295_T	352_L	0.752	1.00
207_L	220_V	0.751	1.00
45_D	48_L	0.751	1.00
157_L	160_V	0.750	1.00
60_L	64_N	0.750	1.00
87_T	146_G	0.750	1.00
97_M	100_N	0.749	1.00
241_T	245_A	0.747	1.00
306_Q	428_L	0.747	1.00
20_L	24_T	0.746	1.00
318_Q	321_V	0.745	1.00
387_D	390_P	0.744	1.00
92_T	98_V	0.744	1.00
328_A	374_V	0.743	1.00
326_H	330_Q	0.743	1.00
384_I	436_G	0.743	1.00
158_A	162_G	0.740	1.00
326_H	329_Q	0.740	1.00
369_P	372_S	0.739	1.00
242_S	245_A	0.736	1.00
397_L	436_G	0.736	1.00
33_W	37_T	0.734	1.00
162_G	165_I	0.734	1.00
434_E	447_V	0.732	1.00
294_L	298_R	0.728	1.00
317_L	376_V	0.727	1.00
156_A	160_V	0.727	1.00
164_L	168_L	0.726	1.00
272_R	275_A	0.726	1.00
342_H	380_A	0.725	1.00
258_Q	279_L	0.725	1.00
200_D	203_S	0.724	1.00
133_W	142_R	0.722	1.00
391_G	443_F	0.721	1.00
214_S	218_P	0.721	1.00
45_D	130_R	0.717	1.00
244_A	293_L	0.716	1.00
352_L	429_H	0.716	1.00
390_P	412_A	0.715	1.00
394_P	438_A	0.715	1.00
376_V	385_V	0.714	1.00
366_R	412_A	0.712	1.00
313_L	346_R	0.711	1.00
306_Q	352_L	0.711	1.00
205_K	209_A	0.709	1.00
213_P	216_V	0.709	1.00
421_I	425_I	0.709	1.00
246_H	359_N	0.709	1.00
130_R	133_W	0.707	1.00
319_S	323_D	0.707	1.00
333_I	365_V	0.705	1.00
187_A	191_K	0.703	1.00
328_A	335_V	0.702	1.00
218_P	222_S	0.702	1.00
219_L	223_L	0.702	1.00
364_A	385_V	0.700	1.00
328_A	331_A	0.696	1.00
236_R	239_R	0.696	1.00
263_Q	276_L	0.692	1.00
318_Q	339_L	0.690	1.00
400_I	420_S	0.689	1.00
196_L	219_L	0.689	1.00
59_D	63_I	0.689	1.00
218_P	221_E	0.687	1.00
221_E	225_Q	0.687	1.00
11_V	15_L	0.686	1.00
40_V	43_L	0.685	1.00
253_T	256_K	0.685	1.00
338_T	379_N	0.685	1.00
196_L	226_L	0.685	1.00
52_A	145_V	0.683	1.00
91_F	144_V	0.682	1.00
199_R	225_Q	0.678	1.00
265_S	268_D	0.678	1.00
220_V	227_F	0.675	1.00
168_L	172_P	0.675	1.00
328_A	333_I	0.674	1.00
141_Y	145_V	0.673	1.00
280_H	283_I	0.672	1.00
315_D	350_P	0.672	1.00
258_Q	262_A	0.672	1.00
324_I	365_V	0.671	1.00
199_R	204_E	0.671	1.00
366_R	414_G	0.668	1.00
38_D	41_D	0.664	1.00
41_D	44_F	0.664	1.00
235_V	238_R	0.664	1.00
63_I	66_A	0.660	1.00
369_P	388_N	0.659	1.00
187_A	190_N	0.659	1.00
322_M	326_H	0.658	1.00
193_A	196_L	0.658	1.00
254_A	278_Q	0.657	1.00
355_L	358_R	0.656	1.00
124_G	127_D	0.656	1.00
209_A	220_V	0.656	1.00
222_S	226_L	0.654	1.00
55_L	58_L	0.651	1.00
275_A	279_L	0.650	1.00
323_D	327_T	0.648	1.00
196_L	199_R	0.647	1.00
50_L	53_K	0.647	1.00
189_L	192_L	0.647	1.00
238_R	300_D	0.646	1.00
311_I	347_T	0.646	1.00
66_A	69_M	0.645	1.00
314_E	344_I	0.644	1.00
329_Q	332_K	0.643	1.00
247_E	289_L	0.642	1.00
46_T	50_L	0.642	1.00
282_G	323_D	0.641	1.00
191_K	194_L	0.640	1.00
42_E	46_T	0.639	1.00
340_N	344_I	0.638	1.00
368_S	371_G	0.637	1.00
352_L	356_L	0.636	1.00
422_V	425_I	0.635	1.00
327_T	331_A	0.635	1.00
284_D	288_R	0.634	1.00
402_E	423_Q	0.634	1.00
10_R	190_N	0.634	1.00
442_G	445_A	0.631	1.00
219_L	222_S	0.629	1.00
378_L	383_F	0.627	1.00
186_L	190_N	0.627	1.00
361_L	374_V	0.627	1.00
92_T	95_G	0.625	1.00
189_L	219_L	0.623	1.00
240_F	247_E	0.622	1.00
30_F	33_W	0.621	1.00
374_V	385_V	0.620	1.00
133_W	144_V	0.619	1.00
420_S	424_R	0.619	1.00
248_L	251_P	0.618	1.00
243_D	247_E	0.618	1.00
35_Q	38_D	0.618	1.00
27_L	31_V	0.617	1.00
321_V	376_V	0.616	1.00
400_I	405_Y	0.613	1.00
390_P	443_F	0.611	1.00
340_N	378_L	0.610	1.00
53_K	56_S	0.609	1.00
247_E	421_I	0.607	1.00
19_I	22_S	0.603	1.00
261_V	275_A	0.603	1.00
321_V	324_I	0.602	1.00
100_N	103_D	0.601	1.00
66_A	70_A	0.601	1.00
275_A	278_Q	0.601	1.00
35_Q	39_N	0.597	1.00
328_A	332_K	0.596	1.00
228_A	232_A	0.595	1.00
246_H	251_P	0.594	1.00
271_A	275_A	0.594	1.00
374_V	378_L	0.593	1.00
50_L	54_R	0.593	1.00
258_Q	283_I	0.593	1.00
240_F	243_D	0.592	1.00
17_F	178_M	0.590	1.00
406_R	413_T	0.590	1.00
316_L	353_L	0.589	1.00
53_K	57_T	0.589	1.00
224_N	228_A	0.588	1.00
201_P	205_K	0.587	1.00
160_V	163_Q	0.585	1.00
331_A	368_S	0.585	1.00
68_R	71_Q	0.585	1.00
238_R	243_D	0.584	1.00
31_V	34_K	0.583	1.00
44_F	48_L	0.583	1.00
393_T	397_L	0.582	1.00
116_G	119_D	0.582	1.00
58_L	62_E	0.580	1.00
195_A	198_M	0.580	1.00
188_P	212_V	0.579	1.00
192_L	196_L	0.579	1.00
306_Q	429_H	0.577	1.00
247_E	250_S	0.576	1.00
226_L	229_R	0.576	1.00
386_R	440_Q	0.576	1.00
272_R	276_L	0.575	1.00
361_L	365_V	0.574	1.00
317_L	320_S	0.573	1.00
16_I	20_L	0.573	1.00
266_D	273_K	0.573	1.00
239_R	424_R	0.573	1.00
316_L	354_S	0.571	1.00
397_L	445_A	0.571	1.00
154_D	158_A	0.568	1.00
122_L	125_E	0.566	1.00
286_A	290_V	0.565	1.00
153_E	157_L	0.565	1.00
398_A	402_E	0.564	1.00
245_A	251_P	0.562	1.00
295_T	298_R	0.561	1.00
276_L	280_H	0.560	1.00
61_N	65_A	0.560	1.00
174_M	178_M	0.559	1.00
129_W	133_W	0.559	1.00
250_S	257_V	0.559	1.00
192_L	220_V	0.559	1.00
287_T	290_V	0.558	1.00
426_A	432_N	0.557	1.00
36_T	39_N	0.556	1.00
324_I	327_T	0.556	1.00
293_L	404_F	0.555	1.00
40_V	44_F	0.553	1.00
314_E	337_L	0.552	1.00
300_D	403_R	0.552	1.00
221_E	224_N	0.552	1.00
158_A	161_A	0.551	1.00
19_I	26_L	0.550	1.00
83_D	86_L	0.550	1.00
38_D	42_E	0.549	1.00
165_I	169_V	0.548	1.00
117_F	120_G	0.547	1.00
209_A	217_R	0.543	1.00
61_N	64_N	0.542	1.00
262_A	275_A	0.542	1.00
48_L	51_F	0.542	1.00
22_S	26_L	0.541	1.00
334_D	371_G	0.540	1.00
39_N	42_E	0.539	1.00
37_T	40_V	0.539	1.00
267_D	271_A	0.537	1.00
238_R	242_S	0.537	1.00
212_V	216_V	0.536	1.00
251_P	286_A	0.536	1.00
18_L	21_A	0.536	1.00
340_N	343_S	0.535	1.00
148_E	151_Y	0.533	1.00
265_S	275_A	0.532	1.00
57_T	61_N	0.532	1.00
392_V	445_A	0.532	1.00
189_L	216_V	0.531	1.00
141_Y	147_Q	0.531	1.00
219_L	224_N	0.531	1.00
10_R	14_T	0.530	1.00
281_S	284_D	0.529	1.00
344_I	347_T	0.528	1.00
331_A	370_Q	0.528	1.00
255_L	259_T	0.528	1.00
65_A	68_R	0.527	1.00
225_Q	228_A	0.526	1.00
230_T	233_M	0.526	1.00
296_L	424_R	0.525	1.00
84_D	87_T	0.524	1.00
249_R	286_A	0.524	1.00
240_F	245_A	0.524	1.00
134_M	137_P	0.523	1.00
253_T	258_Q	0.521	1.00
97_M	101_D	0.521	1.00
74_N	78_H	0.520	1.00
353_L	357_V	0.519	1.00
121_Q	125_E	0.518	1.00
375_D	378_L	0.516	1.00
32_A	36_T	0.515	1.00
12_R	184_R	0.514	1.00
296_L	403_R	0.514	1.00
89_A	100_N	0.513	1.00
369_P	390_P	0.512	1.00
260_E	264_L	0.511	1.00
21_A	174_M	0.511	1.00
238_R	241_T	0.510	1.00
79_G	83_D	0.509	1.00
85_A	88_F	0.509	1.00
292_Q	351_L	0.509	1.00
316_L	319_S	0.508	1.00
315_D	318_Q	0.508	1.00
129_W	146_G	0.507	1.00
255_L	282_G	0.507	1.00
36_T	159_I	0.506	1.00
344_I	378_L	0.506	1.00
57_T	60_L	0.506	1.00
184_R	188_P	0.506	1.00
242_S	403_R	0.505	1.00
312_P	316_L	0.504	1.00
162_G	166_P	0.503	1.00
78_H	82_D	0.503	1.00
248_L	290_V	0.502	1.00
331_A	365_V	0.502	1.00
391_G	400_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.5902	100	0.362	Contact Map
4bixA	2	0.49	100	0.414	Contact Map
4ctiA	2	0.4922	100	0.44	Contact Map
3jz3A	2	0.3541	100	0.454	Contact Map
4q20A	2	0.4967	100	0.467	Contact Map
4mpcA	2	0.6437	100	0.481	Contact Map
4gczA	2	0.7817	100	0.484	Contact Map
3a0rA	2	0.7127	100	0.49	Contact Map
2q8gA	2	0.6459	100	0.498	Contact Map
3d36A	2	0.4744	100	0.5	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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