RCSD - ECOLI - GREMLIN Contacts

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RCSD - Phosphotransferase RcsD

UniProt:	P39838	Sequences: MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNAWLKDKSYQIVDITHAIQKRVDNWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYLEKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLVLISTLPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNMRRLAWQNGHYFTLRTTFNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDATATGNNDNEKEGTDSVSIHFNSTKIEISSALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFSSRSTENVPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHLNLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQAQRLYEKNQQGRMIFMKNIGDALKEPAQSLAESAAKLNAPESKQLANQADVLVRLVDEIQLANMLADDSWKSETVLFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGDRDALRRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLHFPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPEVEEEEERLLDDVCVMVDVTSAEIRNIVTRQLENWGATCITPDERLISQDYDIFLTDNPSNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLGGDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPGKQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12385
Length:	890 (765)
Sequences:	1023 (903)
Seq/√Len:	32.7

ECOLI - RCSD RCSC BARA TORS ARCB EVGS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
748_L	754_E	6.335	1.00
749_L	754_E	6.271	1.00
721_I	732_Y	6.207	1.00
751_S	754_E	6.030	1.00
700_V	706_R	5.099	1.00
620_M	660_I	4.897	1.00
527_F	565_G	4.664	1.00
725_E	743_L	4.580	1.00
441_E	445_N	4.360	1.00
751_S	755_S	4.248	1.00
748_L	751_S	4.104	1.00
451_A	455_Y	3.929	1.00
441_E	444_V	3.876	1.00
737_T	749_L	3.797	1.00
484_A	495_L	3.697	1.00
615_V	619_E	3.646	1.00
750_L	754_E	3.605	1.00
663_R	666_L	3.601	1.00
748_L	755_S	3.506	1.00
343_S	347_N	3.412	1.00
737_T	764_Q	3.158	1.00
705_I	764_Q	3.148	1.00
584_S	629_N	3.096	1.00
749_L	755_S	3.030	1.00
737_T	750_L	2.930	1.00
748_L	753_D	2.926	1.00
706_R	722_T	2.892	1.00
698_V	709_V	2.892	1.00
565_G	654_L	2.879	1.00
483_S	708_I	2.864	1.00
749_L	753_D	2.816	1.00
659_N	671_S	2.799	1.00
629_N	637_G	2.743	1.00
727_L	743_L	2.706	1.00
700_V	741_S	2.706	1.00
481_A	499_A	2.679	1.00
452_Q	455_Y	2.673	1.00
648_D	652_R	2.621	1.00
340_N	343_S	2.617	1.00
616_S	619_E	2.486	1.00
569_A	650_L	2.473	1.00
466_M	469_I	2.468	1.00
227_T	233_L	2.448	0.99
479_S	483_S	2.400	0.99
514_M	629_N	2.399	0.99
442_V	445_N	2.341	0.99
606_F	672_V	2.287	0.99
635_R	638_K	2.287	0.99
385_A	388_L	2.237	0.99
381_S	385_A	2.234	0.99
770_N	775_M	2.221	0.99
343_S	346_V	2.213	0.99
747_G	754_E	2.197	0.99
764_Q	775_M	2.174	0.99
376_N	382_N	2.152	0.99
470_G	474_K	2.136	0.99
340_N	346_V	2.125	0.99
739_N	764_Q	2.124	0.99
700_V	764_Q	2.122	0.98
473_L	477_A	2.120	0.98
700_V	722_T	2.115	0.98
695_C	719_T	2.097	0.98
750_L	762_P	2.091	0.98
544_I	590_I	2.068	0.98
613_E	637_G	2.061	0.98
736_L	764_Q	2.058	0.98
366_L	436_R	2.023	0.98
739_N	775_M	1.979	0.98
469_I	509_I	1.978	0.98
737_T	751_S	1.975	0.98
593_E	607_R	1.955	0.97
481_A	485_A	1.955	0.97
479_S	498_Q	1.943	0.97
391_H	412_I	1.942	0.97
777_E	795_S	1.928	0.97
438_Q	442_V	1.918	0.97
585_T	611_T	1.913	0.97
767_V	770_N	1.902	0.97
609_L	669_R	1.900	0.97
629_N	638_K	1.892	0.97
741_S	744_T	1.885	0.97
632_Q	635_R	1.883	0.97
474_K	583_T	1.877	0.97
469_I	473_L	1.876	0.97
475_E	502_L	1.866	0.97
369_L	433_F	1.861	0.96
423_R	426_V	1.857	0.96
574_L	606_F	1.851	0.96
470_G	475_E	1.847	0.96
472_A	629_N	1.841	0.96
461_G	654_L	1.835	0.96
768_N	772_S	1.830	0.96
565_G	676_M	1.827	0.96
584_S	638_K	1.827	0.96
382_N	385_A	1.804	0.96
467_K	629_N	1.794	0.96
466_M	473_L	1.784	0.96
633_N	638_K	1.771	0.95
484_A	499_A	1.770	0.95
522_S	654_L	1.768	0.95
573_I	672_V	1.763	0.95
412_I	415_E	1.757	0.95
467_K	635_R	1.756	0.95
701_T	746_S	1.753	0.95
573_I	651_A	1.744	0.95
470_G	502_L	1.743	0.95
766_C	770_N	1.741	0.95
569_A	572_R	1.734	0.95
633_N	637_G	1.726	0.95
508_E	572_R	1.721	0.95
632_Q	638_K	1.718	0.94
475_E	583_T	1.699	0.94
651_A	672_V	1.699	0.94
617_I	663_R	1.693	0.94
584_S	637_G	1.690	0.94
737_T	775_M	1.686	0.94
739_N	770_N	1.682	0.94
605_T	671_S	1.680	0.94
737_T	762_P	1.680	0.94
745_A	748_L	1.671	0.94
594_V	606_F	1.667	0.94
476_P	502_L	1.666	0.94
470_G	583_T	1.660	0.93
709_V	765_L	1.657	0.93
547_K	585_T	1.655	0.93
540_V	575_L	1.644	0.93
357_N	360_I	1.642	0.93
367_G	435_I	1.640	0.93
508_E	569_A	1.638	0.93
340_N	347_N	1.637	0.93
474_K	502_L	1.622	0.93
467_K	506_V	1.620	0.93
622_N	628_I	1.610	0.92
737_T	773_N	1.608	0.92
520_W	569_A	1.590	0.92
479_S	708_I	1.586	0.92
459_Q	463_M	1.546	0.91
502_L	583_T	1.539	0.90
438_Q	441_E	1.537	0.90
619_E	622_N	1.537	0.90
750_L	755_S	1.531	0.90
476_P	583_T	1.529	0.90
700_V	739_N	1.522	0.90
565_G	570_L	1.520	0.90
470_G	511_L	1.508	0.90
438_Q	445_N	1.503	0.89
526_L	564_R	1.502	0.89
630_Q	633_N	1.492	0.89
706_R	741_S	1.491	0.89
712_Q	737_T	1.490	0.89
452_Q	456_E	1.489	0.89
470_G	476_P	1.487	0.89
462_R	470_G	1.471	0.88
764_Q	770_N	1.467	0.88
634_D	637_G	1.466	0.88
695_C	721_I	1.460	0.88
703_A	706_R	1.458	0.88
459_Q	462_R	1.455	0.88
629_N	635_R	1.455	0.88
382_N	398_T	1.454	0.88
705_I	737_T	1.454	0.88
593_E	609_L	1.450	0.88
481_A	645_W	1.450	0.88
472_A	644_F	1.449	0.88
747_G	751_S	1.449	0.88
613_E	633_N	1.442	0.87
578_M	592_L	1.429	0.87
465_F	502_L	1.429	0.87
735_F	760_I	1.416	0.86
461_G	482_E	1.406	0.86
726_R	742_N	1.405	0.86
34_M	39_Q	1.403	0.86
549_L	590_I	1.396	0.86
479_S	704_E	1.388	0.85
462_R	502_L	1.387	0.85
691_L	718_A	1.384	0.85
743_L	749_L	1.380	0.85
523_E	565_G	1.380	0.85
740_P	764_Q	1.379	0.85
616_S	664_D	1.377	0.85
507_D	511_L	1.374	0.85
440_R	443_L	1.373	0.85
479_S	484_A	1.370	0.84
462_R	475_E	1.364	0.84
742_N	746_S	1.362	0.84
762_P	775_M	1.355	0.84
474_K	584_S	1.354	0.84
498_Q	766_C	1.338	0.83
470_G	584_S	1.337	0.83
766_C	778_A	1.337	0.83
741_S	766_C	1.336	0.83
694_V	796_P	1.334	0.83
739_N	778_A	1.332	0.83
585_T	588_G	1.330	0.83
709_V	764_Q	1.328	0.82
465_F	474_K	1.324	0.82
461_G	498_Q	1.324	0.82
475_E	511_L	1.316	0.82
726_R	744_T	1.311	0.82
445_N	448_L	1.307	0.81
634_D	638_K	1.306	0.81
468_N	480_L	1.301	0.81
501_V	505_L	1.296	0.81
463_M	640_D	1.296	0.81
479_S	705_I	1.296	0.81
495_L	499_A	1.293	0.81
630_Q	638_K	1.291	0.81
661_K	669_R	1.290	0.81
455_Y	482_E	1.289	0.81
473_L	501_V	1.284	0.80
465_F	583_T	1.284	0.80
514_M	640_D	1.282	0.80
467_K	585_T	1.274	0.80
455_Y	461_G	1.271	0.80
699_D	741_S	1.267	0.79
750_L	766_C	1.266	0.79
139_E	142_P	1.264	0.79
474_K	511_L	1.256	0.79
705_I	775_M	1.255	0.79
440_R	444_V	1.250	0.78
615_V	644_F	1.244	0.78
455_Y	654_L	1.241	0.78
754_E	762_P	1.241	0.78
739_N	766_C	1.240	0.78
615_V	660_I	1.240	0.78
495_L	670_Y	1.233	0.77
423_R	433_F	1.228	0.77
702_S	705_I	1.228	0.77
468_N	740_P	1.226	0.77
390_P	414_N	1.226	0.77
166_L	169_G	1.224	0.77
737_T	741_S	1.221	0.77
706_R	724_D	1.220	0.77
750_L	775_M	1.213	0.76
701_T	781_Q	1.212	0.76
603_R	675_K	1.211	0.76
737_T	743_L	1.207	0.76
770_N	778_A	1.204	0.76
771_M	775_M	1.200	0.75
539_S	551_L	1.199	0.75
528_S	531_D	1.199	0.75
444_V	447_K	1.198	0.75
458_N	461_G	1.197	0.75
475_E	584_S	1.196	0.75
381_S	384_I	1.191	0.75
726_R	741_S	1.191	0.75
466_M	474_K	1.187	0.75
469_I	515_L	1.181	0.74
699_D	749_L	1.180	0.74
705_I	776_Q	1.176	0.74
774_A	778_A	1.173	0.74
477_A	483_S	1.172	0.74
466_M	511_L	1.167	0.73
572_R	646_L	1.166	0.73
465_F	470_G	1.164	0.73
737_T	740_P	1.163	0.73
480_L	503_V	1.162	0.73
477_A	732_Y	1.161	0.73
573_I	650_L	1.160	0.73
462_R	583_T	1.160	0.73
512_A	702_S	1.160	0.73
698_V	720_C	1.159	0.73
227_T	290_M	1.158	0.73
563_R	676_M	1.153	0.72
370_V	430_T	1.144	0.72
696_V	718_A	1.143	0.72
458_N	466_M	1.141	0.72
506_V	515_L	1.138	0.71
696_V	734_I	1.138	0.71
741_S	745_A	1.136	0.71
474_K	629_N	1.133	0.71
75_Y	80_A	1.131	0.71
382_N	388_L	1.130	0.71
629_N	644_F	1.130	0.71
71_T	75_Y	1.128	0.71
467_K	584_S	1.122	0.70
451_A	461_G	1.119	0.70
462_R	476_P	1.118	0.70
632_Q	637_G	1.118	0.70
476_P	585_T	1.114	0.70
382_N	430_T	1.112	0.70
430_T	433_F	1.112	0.70
451_A	456_E	1.112	0.70
481_A	503_V	1.109	0.69
764_Q	774_A	1.107	0.69
511_L	584_S	1.106	0.69
463_M	516_A	1.103	0.69
467_K	470_G	1.101	0.69
525_V	567_R	1.101	0.69
524_T	565_G	1.099	0.69
478_Q	498_Q	1.099	0.69
754_E	760_I	1.096	0.69
448_L	451_A	1.096	0.69
217_T	227_T	1.095	0.69
767_V	777_E	1.095	0.69
502_L	584_S	1.094	0.68
701_T	742_N	1.091	0.68
695_C	732_Y	1.089	0.68
354_R	357_N	1.087	0.68
468_N	712_Q	1.086	0.68
462_R	474_K	1.086	0.68
466_M	475_E	1.086	0.68
472_A	475_E	1.085	0.68
357_N	381_S	1.082	0.68
573_I	654_L	1.082	0.68
746_S	781_Q	1.082	0.68
699_D	706_R	1.080	0.67
754_E	775_M	1.080	0.67
490_P	698_V	1.077	0.67
650_L	654_L	1.076	0.67
468_N	478_Q	1.075	0.67
477_A	675_K	1.075	0.67
647_S	672_V	1.072	0.67
725_E	737_T	1.071	0.67
414_N	418_E	1.071	0.67
483_S	732_Y	1.068	0.67
420_R	423_R	1.067	0.66
652_R	657_H	1.067	0.66
705_I	739_N	1.066	0.66
513_N	517_D	1.056	0.66
472_A	635_R	1.054	0.65
699_D	737_T	1.053	0.65
473_L	483_S	1.053	0.65
465_F	475_E	1.052	0.65
466_M	470_G	1.050	0.65
705_I	774_A	1.047	0.65
737_T	766_C	1.047	0.65
696_V	713_L	1.047	0.65
735_F	762_P	1.047	0.65
467_K	474_K	1.046	0.65
749_L	775_M	1.044	0.65
465_F	469_I	1.044	0.65
470_G	646_L	1.042	0.65
470_G	629_N	1.042	0.65
473_L	702_S	1.041	0.65
577_L	672_V	1.040	0.64
465_F	629_N	1.040	0.64
472_A	584_S	1.038	0.64
517_D	629_N	1.034	0.64
506_V	516_A	1.032	0.64
585_T	642_L	1.031	0.64
476_P	584_S	1.030	0.64
506_V	512_A	1.030	0.64
705_I	741_S	1.026	0.63
569_A	783_I	1.024	0.63
466_M	477_A	1.021	0.63
531_D	796_P	1.021	0.63
700_V	725_E	1.019	0.63
61_Q	64_V	1.017	0.63
502_L	511_L	1.017	0.63
469_I	477_A	1.015	0.63
737_T	754_E	1.014	0.62
440_R	445_N	1.013	0.62
754_E	776_Q	1.011	0.62
520_W	604_L	1.011	0.62
660_I	670_Y	1.010	0.62
623_L	657_H	1.008	0.62
462_R	466_M	1.006	0.62
584_S	633_N	1.004	0.62
644_F	668_T	1.004	0.62
763_G	767_V	1.000	0.61
411_T	419_I	0.999	0.61
468_N	585_T	0.996	0.61
473_L	505_L	0.995	0.61
583_T	629_N	0.994	0.61
777_E	791_E	0.992	0.61
475_E	629_N	0.992	0.61
605_T	673_H	0.991	0.61
473_L	732_Y	0.990	0.61
475_E	569_A	0.989	0.60
577_L	608_I	0.989	0.60
371_H	385_A	0.987	0.60
752_D	755_S	0.987	0.60
466_M	476_P	0.987	0.60
749_L	764_Q	0.984	0.60
416_L	419_I	0.984	0.60
432_I	435_I	0.978	0.60
583_T	646_L	0.976	0.59
463_M	502_L	0.976	0.59
751_S	775_M	0.975	0.59
777_E	794_E	0.975	0.59
462_R	465_F	0.975	0.59
278_K	295_Q	0.974	0.59
764_Q	773_N	0.964	0.58
709_V	712_Q	0.964	0.58
474_K	646_L	0.963	0.58
64_V	71_T	0.962	0.58
708_I	775_M	0.960	0.58
511_L	520_W	0.960	0.58
437_D	445_N	0.958	0.58
507_D	516_A	0.957	0.58
467_K	583_T	0.956	0.58
540_V	582_V	0.956	0.58
486_K	623_L	0.953	0.58
412_I	419_I	0.953	0.58
472_A	583_T	0.952	0.58
470_G	572_R	0.949	0.57
606_F	647_S	0.948	0.57
584_S	642_L	0.947	0.57
74_I	78_I	0.946	0.57
419_I	423_R	0.944	0.57
471_D	576_L	0.944	0.57
238_L	241_P	0.944	0.57
472_A	615_V	0.943	0.57
642_L	646_L	0.943	0.57
511_L	583_T	0.941	0.57
475_E	508_E	0.941	0.57
510_Q	624_H	0.939	0.56
467_K	475_E	0.936	0.56
501_V	539_S	0.935	0.56
227_T	230_A	0.933	0.56
370_V	385_A	0.933	0.56
472_A	476_P	0.930	0.56
483_S	637_G	0.930	0.56
238_L	242_G	0.929	0.56
584_S	646_L	0.928	0.56
483_S	775_M	0.928	0.56
349_E	353_L	0.924	0.55
644_F	670_Y	0.921	0.55
480_L	704_E	0.918	0.55
747_G	755_S	0.917	0.55
766_C	775_M	0.916	0.55
523_E	635_R	0.915	0.54
474_K	585_T	0.914	0.54
475_E	572_R	0.912	0.54
506_V	741_S	0.912	0.54
607_R	671_S	0.911	0.54
595_D	605_T	0.906	0.54
35_G	39_Q	0.903	0.54
505_L	557_L	0.902	0.53
568_D	615_V	0.901	0.53
354_R	358_E	0.900	0.53
164_K	169_G	0.898	0.53
466_M	547_K	0.897	0.53
471_D	580_Y	0.897	0.53
478_Q	705_I	0.895	0.53
487_L	653_K	0.894	0.53
597_D	605_T	0.891	0.53
472_A	572_R	0.891	0.53
531_D	625_F	0.891	0.53
467_K	472_A	0.890	0.52
713_L	763_G	0.890	0.52
702_S	709_V	0.890	0.52
700_V	765_L	0.886	0.52
465_F	476_P	0.886	0.52
469_I	516_A	0.886	0.52
736_L	788_A	0.885	0.52
448_L	623_L	0.884	0.52
721_I	730_Q	0.881	0.52
473_L	508_E	0.881	0.52
22_F	29_V	0.880	0.52
293_V	297_P	0.879	0.52
757_V	760_I	0.877	0.51
584_S	644_F	0.876	0.51
624_H	639_A	0.875	0.51
706_R	775_M	0.875	0.51
483_S	635_R	0.874	0.51
420_R	426_V	0.872	0.51
467_K	642_L	0.872	0.51
756_G	762_P	0.872	0.51
423_R	427_A	0.871	0.51
414_N	420_R	0.870	0.51
29_V	38_V	0.869	0.51
390_P	412_I	0.869	0.51
473_L	499_A	0.866	0.50
705_I	747_G	0.865	0.50
364_L	368_L	0.865	0.50
716_W	737_T	0.863	0.50
431_Q	434_I	0.863	0.50
726_R	737_T	0.863	0.50
465_F	585_T	0.863	0.50
747_G	750_L	0.862	0.50
469_I	503_V	0.861	0.50
371_H	433_F	0.861	0.50
372_D	439_D	0.861	0.50
502_L	629_N	0.859	0.50
726_R	746_S	0.859	0.50
418_E	433_F	0.857	0.50
616_S	623_L	0.857	0.50
768_N	778_A	0.856	0.50
350_L	579_Q	0.856	0.50
615_V	620_M	0.854	0.49
509_I	516_A	0.854	0.49
31_L	34_M	0.853	0.49
501_V	654_L	0.853	0.49
541_L	545_K	0.852	0.49
479_S	487_L	0.851	0.49
483_S	565_G	0.851	0.49
480_L	487_L	0.851	0.49
520_W	584_S	0.851	0.49
471_D	643_A	0.850	0.49
736_L	765_L	0.850	0.49
584_S	635_R	0.848	0.49
589_K	700_V	0.848	0.49
461_G	469_I	0.848	0.49
740_P	765_L	0.847	0.49
502_L	507_D	0.845	0.49
478_Q	486_K	0.842	0.48
770_N	780_L	0.842	0.48
370_V	433_F	0.841	0.48
745_A	779_V	0.840	0.48
479_S	482_E	0.838	0.48
702_S	740_P	0.837	0.48
466_M	502_L	0.837	0.48
725_E	750_L	0.836	0.48
395_Q	412_I	0.835	0.48
465_F	584_S	0.833	0.48
476_P	511_L	0.833	0.48
479_S	505_L	0.830	0.47
218_T	227_T	0.828	0.47
576_L	580_Y	0.828	0.47
495_L	503_V	0.825	0.47
734_I	796_P	0.825	0.47
741_S	763_G	0.822	0.47
473_L	775_M	0.819	0.47
236_N	240_P	0.819	0.47
572_R	642_L	0.817	0.46
476_P	646_L	0.816	0.46
425_Q	439_D	0.816	0.46
484_A	503_V	0.816	0.46
21_R	24_L	0.816	0.46
576_L	643_A	0.815	0.46
381_S	388_L	0.814	0.46
478_Q	513_N	0.814	0.46
463_M	512_A	0.813	0.46
473_L	718_A	0.812	0.46
475_E	585_T	0.812	0.46
705_I	723_P	0.812	0.46
477_A	505_L	0.811	0.46
646_L	654_L	0.811	0.46
128_M	136_W	0.811	0.46
509_I	578_M	0.810	0.46
742_N	745_A	0.810	0.46
767_V	773_N	0.810	0.46
458_N	462_R	0.808	0.46
447_K	452_Q	0.808	0.46
482_E	575_L	0.804	0.45
88_E	91_Q	0.802	0.45
474_K	572_R	0.801	0.45
415_E	418_E	0.801	0.45
411_T	418_E	0.800	0.45
477_A	506_V	0.799	0.45
475_E	507_D	0.798	0.45
479_S	676_M	0.797	0.45
585_T	646_L	0.797	0.45
508_E	646_L	0.797	0.45
372_D	377_R	0.797	0.45
418_E	423_R	0.796	0.45
201_N	211_H	0.796	0.45
474_K	507_D	0.796	0.45
398_T	413_N	0.795	0.45
372_D	425_Q	0.795	0.45
747_G	753_D	0.794	0.45
466_M	572_R	0.793	0.44
723_P	726_R	0.793	0.44
483_S	739_N	0.793	0.44
70_V	74_I	0.792	0.44
495_L	766_C	0.789	0.44
503_V	506_V	0.789	0.44
712_Q	785_V	0.787	0.44
454_L	457_K	0.785	0.44
364_L	367_G	0.785	0.44
699_D	709_V	0.785	0.44
706_R	764_Q	0.784	0.44
418_E	442_V	0.783	0.44
481_A	508_E	0.782	0.44
481_A	567_R	0.780	0.43
485_A	501_V	0.780	0.43
478_Q	653_K	0.778	0.43
430_T	435_I	0.778	0.43
23_F	26_L	0.778	0.43
251_E	256_A	0.777	0.43
445_N	449_K	0.776	0.43
455_Y	459_Q	0.776	0.43
740_P	775_M	0.776	0.43
740_P	770_N	0.775	0.43
736_L	775_M	0.773	0.43
471_D	510_Q	0.773	0.43
473_L	649_Q	0.772	0.43
511_L	569_A	0.772	0.43
462_R	584_S	0.772	0.43
555_N	559_A	0.771	0.43
573_I	606_F	0.770	0.43
75_Y	78_I	0.769	0.42
432_I	436_R	0.767	0.42
467_K	572_R	0.766	0.42
502_L	585_T	0.766	0.42
470_G	585_T	0.764	0.42
478_Q	704_E	0.763	0.42
630_Q	637_G	0.763	0.42
467_K	637_G	0.761	0.42
149_N	152_D	0.761	0.42
508_E	520_W	0.761	0.42
579_Q	583_T	0.759	0.42
481_A	506_V	0.759	0.42
622_N	763_G	0.757	0.41
360_I	367_G	0.757	0.41
501_V	512_A	0.757	0.41
29_V	32_V	0.756	0.41
452_Q	459_Q	0.755	0.41
653_K	766_C	0.755	0.41
481_A	497_N	0.755	0.41
467_K	505_L	0.755	0.41
645_W	699_D	0.755	0.41
543_A	579_Q	0.753	0.41
764_Q	778_A	0.751	0.41
630_Q	634_D	0.751	0.41
505_L	512_A	0.751	0.41
770_N	774_A	0.750	0.41
734_I	792_V	0.750	0.41
502_L	646_L	0.750	0.41
464_I	479_S	0.749	0.41
359_E	371_H	0.749	0.41
297_P	300_T	0.748	0.41
576_L	624_H	0.748	0.41
467_K	511_L	0.748	0.41
365_P	382_N	0.747	0.41
704_E	764_Q	0.746	0.41
360_I	370_V	0.746	0.41
735_F	768_N	0.746	0.41
470_G	510_Q	0.745	0.41
458_N	463_M	0.743	0.40
693_D	718_A	0.743	0.40
463_M	474_K	0.741	0.40
572_R	584_S	0.741	0.40
458_N	654_L	0.739	0.40
411_T	415_E	0.739	0.40
509_I	638_K	0.738	0.40
486_K	551_L	0.738	0.40
480_L	484_A	0.738	0.40
467_K	476_P	0.737	0.40
26_L	29_V	0.736	0.40
476_P	507_D	0.736	0.40
486_K	711_R	0.735	0.40
501_V	626_P	0.735	0.40
508_E	583_T	0.735	0.40
27_I	34_M	0.734	0.40
619_E	630_Q	0.733	0.40
502_L	514_M	0.733	0.40
510_Q	572_R	0.732	0.40
422_F	551_L	0.732	0.40
475_E	646_L	0.730	0.39
509_I	513_N	0.729	0.39
185_E	188_Q	0.729	0.39
501_V	571_R	0.728	0.39
762_P	776_Q	0.727	0.39
152_D	155_L	0.726	0.39
395_Q	398_T	0.724	0.39
396_N	399_T	0.723	0.39
704_E	775_M	0.722	0.39
455_Y	501_V	0.722	0.39
507_D	583_T	0.722	0.39
737_T	753_D	0.722	0.39
590_I	795_S	0.720	0.39
606_F	653_K	0.720	0.39
705_I	763_G	0.719	0.38
168_S	235_I	0.719	0.38
353_L	356_I	0.719	0.38
739_N	765_L	0.718	0.38
553_I	766_C	0.718	0.38
42_V	46_L	0.717	0.38
472_A	514_M	0.717	0.38
498_Q	704_E	0.717	0.38
585_T	629_N	0.717	0.38
750_L	753_D	0.717	0.38
543_A	546_R	0.717	0.38
615_V	621_D	0.716	0.38
468_N	584_S	0.715	0.38
414_N	433_F	0.715	0.38
461_G	479_S	0.714	0.38
67_W	71_T	0.714	0.38
472_A	647_S	0.713	0.38
736_L	750_L	0.713	0.38
349_E	352_I	0.713	0.38
694_V	718_A	0.713	0.38
48_D	51_Y	0.713	0.38
471_D	624_H	0.713	0.38
472_A	502_L	0.712	0.38
570_L	676_M	0.712	0.38
474_K	514_M	0.712	0.38
482_E	713_L	0.712	0.38
654_L	705_I	0.712	0.38
509_I	633_N	0.711	0.38
762_P	766_C	0.711	0.38
483_S	737_T	0.711	0.38
509_I	515_L	0.711	0.38
463_M	470_G	0.710	0.38
483_S	765_L	0.710	0.38
472_A	619_E	0.709	0.38
499_A	775_M	0.709	0.38
613_E	634_D	0.708	0.38
470_G	569_A	0.708	0.38
515_L	518_D	0.708	0.38
483_S	498_Q	0.707	0.38
580_Y	643_A	0.706	0.37
412_I	416_L	0.704	0.37
566_D	585_T	0.703	0.37
466_M	583_T	0.702	0.37
632_Q	636_Y	0.702	0.37
592_L	606_F	0.702	0.37
699_D	726_R	0.700	0.37
623_L	645_W	0.700	0.37
527_F	674_I	0.700	0.37
469_I	501_V	0.700	0.37
754_E	757_V	0.699	0.37
498_Q	705_I	0.699	0.37
741_S	764_Q	0.697	0.37
287_S	648_D	0.697	0.37
325_F	395_Q	0.696	0.37
502_L	508_E	0.696	0.37
465_F	579_Q	0.696	0.37
499_A	766_C	0.694	0.37
630_Q	766_C	0.693	0.36
616_S	626_P	0.693	0.36
486_K	770_N	0.692	0.36
473_L	675_K	0.691	0.36
737_T	748_L	0.691	0.36
462_R	511_L	0.690	0.36
199_F	202_M	0.690	0.36
60_I	63_R	0.690	0.36
629_N	634_D	0.689	0.36
630_Q	635_R	0.688	0.36
477_A	628_I	0.688	0.36
424_S	427_A	0.687	0.36
573_I	773_N	0.687	0.36
741_S	776_Q	0.687	0.36
517_D	630_Q	0.687	0.36
750_L	773_N	0.686	0.36
519_S	573_I	0.686	0.36
367_G	385_A	0.686	0.36
482_E	705_I	0.685	0.36
705_I	762_P	0.685	0.36
726_R	774_A	0.684	0.36
511_L	515_L	0.684	0.36
371_H	378_T	0.684	0.36
479_S	706_R	0.684	0.36
418_E	426_V	0.683	0.36
701_T	726_R	0.683	0.36
713_L	792_V	0.683	0.36
469_I	478_Q	0.683	0.36
473_L	485_A	0.683	0.36
734_I	765_L	0.683	0.36
572_R	629_N	0.682	0.36
701_T	741_S	0.681	0.36
704_E	708_I	0.681	0.36
468_N	475_E	0.681	0.36
467_K	653_K	0.681	0.36
463_M	467_K	0.681	0.36
701_T	744_T	0.681	0.36
468_N	619_E	0.681	0.36
483_S	704_E	0.681	0.36
466_M	516_A	0.681	0.36
108_K	112_L	0.679	0.35
466_M	584_S	0.679	0.35
467_K	502_L	0.679	0.35
502_L	572_R	0.677	0.35
700_V	740_P	0.677	0.35
483_S	501_V	0.677	0.35
433_F	441_E	0.676	0.35
650_L	736_L	0.675	0.35
572_R	640_D	0.674	0.35
569_A	736_L	0.673	0.35
626_P	737_T	0.673	0.35
420_R	424_S	0.673	0.35
624_H	670_Y	0.672	0.35
569_A	583_T	0.672	0.35
705_I	773_N	0.672	0.35
725_E	741_S	0.672	0.35
699_D	702_S	0.671	0.35
725_E	778_A	0.671	0.35
482_E	510_Q	0.670	0.35
142_P	146_Y	0.670	0.35
466_M	503_V	0.669	0.35
483_S	512_A	0.669	0.35
691_L	708_I	0.669	0.35
791_E	796_P	0.669	0.35
469_I	645_W	0.668	0.35
718_A	792_V	0.666	0.34
392_L	651_A	0.666	0.34
764_Q	780_L	0.665	0.34
458_N	479_S	0.665	0.34
698_V	795_S	0.665	0.34
343_S	353_L	0.663	0.34
463_M	473_L	0.663	0.34
370_V	383_K	0.663	0.34
479_S	506_V	0.662	0.34
384_I	387_H	0.661	0.34
382_N	386_D	0.661	0.34
126_Q	130_T	0.661	0.34
515_L	649_Q	0.661	0.34
701_T	738_D	0.659	0.34
647_S	658_L	0.658	0.34
292_L	317_I	0.658	0.34
489_A	536_V	0.658	0.34
116_S	119_N	0.658	0.34
615_V	618_H	0.657	0.34
740_P	766_C	0.657	0.34
514_M	585_T	0.657	0.34
360_I	430_T	0.656	0.34
507_D	646_L	0.656	0.34
201_N	235_I	0.656	0.34
635_R	740_P	0.655	0.34
340_N	353_L	0.655	0.34
604_L	674_I	0.654	0.34
368_L	376_N	0.654	0.34
702_S	737_T	0.653	0.33
466_M	515_L	0.653	0.33
350_L	354_R	0.653	0.33
501_V	575_L	0.653	0.33
423_R	430_T	0.652	0.33
568_D	571_R	0.652	0.33
625_F	628_I	0.652	0.33
705_I	766_C	0.652	0.33
226_A	230_A	0.651	0.33
647_S	770_N	0.651	0.33
476_P	629_N	0.650	0.33
507_D	584_S	0.649	0.33
469_I	474_K	0.649	0.33
422_F	426_V	0.648	0.33
273_H	278_K	0.648	0.33
506_V	517_D	0.648	0.33
355_A	578_M	0.647	0.33
766_C	776_Q	0.647	0.33
323_A	327_Y	0.645	0.33
620_M	623_L	0.645	0.33
535_E	775_M	0.644	0.33
465_F	507_D	0.644	0.33
556_H	733_D	0.644	0.33
23_F	30_L	0.644	0.33
462_R	585_T	0.643	0.33
788_A	792_V	0.642	0.33
418_E	425_Q	0.641	0.33
423_R	431_Q	0.641	0.33
463_M	475_E	0.641	0.33
732_Y	754_E	0.639	0.32
463_M	466_M	0.639	0.32
489_A	638_K	0.639	0.32
462_R	472_A	0.638	0.32
506_V	509_I	0.637	0.32
99_V	112_L	0.637	0.32
569_A	584_S	0.636	0.32
511_L	646_L	0.636	0.32
416_L	423_R	0.635	0.32
466_M	472_A	0.635	0.32
511_L	516_A	0.635	0.32
511_L	572_R	0.633	0.32
45_W	49_K	0.632	0.32
194_D	200_S	0.632	0.32
572_R	583_T	0.632	0.32
576_L	639_A	0.631	0.32
582_V	705_I	0.631	0.32
437_D	442_V	0.630	0.32
705_I	770_N	0.630	0.32
384_I	388_L	0.630	0.32
659_N	672_V	0.629	0.32
371_H	376_N	0.628	0.32
378_T	381_S	0.628	0.32
473_L	646_L	0.628	0.32
132_L	146_Y	0.627	0.32
369_L	430_T	0.626	0.31
71_T	74_I	0.626	0.31
607_R	728_I	0.626	0.31
514_M	583_T	0.625	0.31
528_S	561_D	0.625	0.31
468_N	472_A	0.625	0.31
473_L	484_A	0.625	0.31
473_L	511_L	0.623	0.31
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423_R	434_I	0.622	0.31
530_Q	674_I	0.622	0.31
35_G	42_V	0.622	0.31
34_M	38_V	0.621	0.31
463_M	469_I	0.621	0.31
518_D	733_D	0.620	0.31
699_D	723_P	0.620	0.31
709_V	718_A	0.620	0.31
739_N	777_E	0.620	0.31
419_I	441_E	0.619	0.31
51_Y	320_L	0.618	0.31
514_M	635_R	0.618	0.31
474_K	579_Q	0.616	0.31
615_V	668_T	0.616	0.31
482_E	572_R	0.616	0.31
478_Q	708_I	0.615	0.31
378_T	431_Q	0.614	0.31
506_V	704_E	0.613	0.31
448_L	452_Q	0.613	0.31
350_L	515_L	0.612	0.30
479_S	568_D	0.611	0.30
651_A	674_I	0.611	0.30
480_L	515_L	0.611	0.30
474_K	510_Q	0.609	0.30
723_P	737_T	0.609	0.30
468_N	503_V	0.608	0.30
544_I	582_V	0.608	0.30
477_A	523_E	0.608	0.30
350_L	353_L	0.607	0.30
465_F	511_L	0.606	0.30
438_Q	444_V	0.606	0.30
391_H	414_N	0.606	0.30
608_I	733_D	0.606	0.30
353_L	369_L	0.605	0.30
578_M	608_I	0.605	0.30
499_A	568_D	0.605	0.30
468_N	476_P	0.604	0.30
771_M	774_A	0.604	0.30
388_L	391_H	0.604	0.30
505_L	656_G	0.603	0.30
619_E	623_L	0.603	0.30
179_V	182_R	0.603	0.30
79_A	85_S	0.603	0.30
740_P	743_L	0.603	0.30
619_E	633_N	0.603	0.30
462_R	506_V	0.601	0.30
512_A	635_R	0.601	0.30
485_A	712_Q	0.601	0.30
478_Q	503_V	0.601	0.30
426_V	434_I	0.601	0.30
529_V	574_L	0.601	0.30
513_N	638_K	0.600	0.30
465_F	624_H	0.600	0.30
469_I	640_D	0.600	0.30
463_M	581_A	0.599	0.30
510_Q	576_L	0.597	0.29
584_S	647_S	0.596	0.29
705_I	725_E	0.596	0.29
466_M	509_I	0.595	0.29
53_I	309_I	0.595	0.29
437_D	441_E	0.594	0.29
625_F	645_W	0.594	0.29
279_I	305_T	0.593	0.29
431_Q	436_R	0.592	0.29
465_F	514_M	0.592	0.29
694_V	733_D	0.591	0.29
503_V	516_A	0.590	0.29
626_P	647_S	0.590	0.29
398_T	430_T	0.589	0.29
482_E	654_L	0.589	0.29
32_V	39_Q	0.587	0.29
470_G	507_D	0.587	0.29
699_D	705_I	0.587	0.29
503_V	606_F	0.586	0.29
501_V	702_S	0.585	0.29
764_Q	795_S	0.585	0.29
702_S	764_Q	0.585	0.29
327_Y	331_R	0.585	0.29
483_S	650_L	0.585	0.29
697_M	723_P	0.585	0.29
23_F	29_V	0.584	0.29
741_S	746_S	0.584	0.29
193_L	199_F	0.584	0.29
203_R	258_G	0.583	0.28
739_N	749_L	0.583	0.28
212_Y	219_F	0.583	0.28
509_I	571_R	0.583	0.28
452_Q	611_T	0.583	0.28
459_Q	501_V	0.582	0.28
644_F	647_S	0.580	0.28
463_M	506_V	0.580	0.28
370_V	382_N	0.580	0.28
543_A	672_V	0.578	0.28
459_Q	467_K	0.577	0.28
431_Q	435_I	0.575	0.28
478_Q	654_L	0.575	0.28
569_A	668_T	0.575	0.28
624_H	643_A	0.575	0.28
468_N	704_E	0.574	0.28
701_T	704_E	0.573	0.28
433_F	438_Q	0.573	0.28
535_E	777_E	0.572	0.28
750_L	792_V	0.572	0.28
390_P	442_V	0.571	0.28
706_R	737_T	0.571	0.28
770_N	777_E	0.570	0.28
466_M	629_N	0.569	0.28
478_Q	627_F	0.568	0.27
508_E	650_L	0.568	0.27
583_T	624_H	0.568	0.27
365_P	370_V	0.568	0.27
485_A	623_L	0.568	0.27
466_M	585_T	0.567	0.27
702_S	736_L	0.567	0.27
478_Q	483_S	0.567	0.27
551_L	559_A	0.566	0.27
638_K	766_C	0.566	0.27
483_S	495_L	0.566	0.27
470_G	579_Q	0.566	0.27
441_E	452_Q	0.565	0.27
628_I	654_L	0.565	0.27
658_L	672_V	0.564	0.27
736_L	786_Q	0.564	0.27
580_Y	639_A	0.564	0.27
765_L	770_N	0.563	0.27
590_I	739_N	0.563	0.27
472_A	511_L	0.563	0.27
33_T	41_A	0.562	0.27
412_I	420_R	0.562	0.27
511_L	585_T	0.562	0.27
590_I	725_E	0.561	0.27
471_D	639_A	0.560	0.27
383_K	390_P	0.560	0.27
616_S	630_Q	0.560	0.27
250_L	529_V	0.560	0.27
473_L	584_S	0.560	0.27
384_I	439_D	0.559	0.27
737_T	763_G	0.558	0.27
533_I	779_V	0.558	0.27
697_M	701_T	0.558	0.27
702_S	708_I	0.556	0.27
549_L	700_V	0.556	0.27
767_V	775_M	0.556	0.27
700_V	761_G	0.555	0.27
471_D	475_E	0.555	0.27
749_L	752_D	0.555	0.27
474_K	569_A	0.555	0.27
467_K	638_K	0.554	0.27
461_G	466_M	0.554	0.27
317_I	325_F	0.553	0.27
237_D	241_P	0.553	0.27
483_S	486_K	0.553	0.27
462_R	478_Q	0.553	0.27
619_E	638_K	0.552	0.26
706_R	725_E	0.552	0.26
511_L	613_E	0.551	0.26
728_I	755_S	0.551	0.26
457_K	522_S	0.551	0.26
146_Y	152_D	0.550	0.26
461_G	478_Q	0.550	0.26
502_L	569_A	0.550	0.26
484_A	785_V	0.550	0.26
465_F	503_V	0.550	0.26
238_L	244_P	0.550	0.26
472_A	569_A	0.549	0.26
779_V	787_L	0.549	0.26
502_L	640_D	0.548	0.26
705_I	740_P	0.548	0.26
412_I	417_Y	0.548	0.26
60_I	64_V	0.548	0.26
741_S	747_G	0.547	0.26
31_L	35_G	0.547	0.26
142_P	150_G	0.547	0.26
519_S	648_D	0.547	0.26
87_G	90_L	0.546	0.26
270_V	275_N	0.545	0.26
741_S	750_L	0.545	0.26
342_P	346_V	0.545	0.26
621_D	660_I	0.544	0.26
500_D	784_E	0.544	0.26
434_I	437_D	0.542	0.26
764_Q	771_M	0.542	0.26
750_L	765_L	0.541	0.26
485_A	778_A	0.541	0.26
207_W	211_H	0.540	0.26
98_D	102_L	0.540	0.26
199_F	203_R	0.539	0.26
321_A	680_D	0.539	0.26
664_D	752_D	0.539	0.26
441_E	458_N	0.538	0.26
629_N	632_Q	0.538	0.26
38_V	53_I	0.537	0.25
506_V	583_T	0.537	0.25
484_A	660_I	0.537	0.25
706_R	709_V	0.536	0.25
457_K	654_L	0.535	0.25
236_N	242_G	0.534	0.25
20_T	24_L	0.534	0.25
171_K	182_R	0.534	0.25
451_A	459_Q	0.533	0.25
540_V	585_T	0.533	0.25
741_S	749_L	0.532	0.25
580_Y	624_H	0.532	0.25
700_V	718_A	0.532	0.25
712_Q	749_L	0.532	0.25
468_N	626_P	0.531	0.25
584_S	632_Q	0.531	0.25
524_T	779_V	0.530	0.25
782_L	788_A	0.530	0.25
483_S	735_F	0.529	0.25
459_Q	475_E	0.529	0.25
523_E	765_L	0.529	0.25
465_F	510_Q	0.528	0.25
747_G	762_P	0.528	0.25
78_I	81_T	0.528	0.25
228_V	232_D	0.527	0.25
508_E	654_L	0.527	0.25
739_N	767_V	0.526	0.25
383_K	442_V	0.526	0.25
542_P	796_P	0.526	0.25
512_A	516_A	0.525	0.25
738_D	746_S	0.524	0.25
760_I	778_A	0.524	0.25
468_N	583_T	0.523	0.25
742_N	774_A	0.523	0.25
466_M	654_L	0.521	0.24
361_V	381_S	0.521	0.24
94_R	100_Y	0.520	0.24
510_Q	580_Y	0.520	0.24
385_A	418_E	0.520	0.24
137_G	147_Y	0.519	0.24
739_N	743_L	0.518	0.24
747_G	766_C	0.518	0.24
554_N	593_E	0.518	0.24
594_V	744_T	0.518	0.24
462_R	468_N	0.518	0.24
517_D	626_P	0.517	0.24
467_K	646_L	0.517	0.24
19_I	698_V	0.517	0.24
519_S	582_V	0.517	0.24
736_L	747_G	0.516	0.24
754_E	770_N	0.516	0.24
512_A	525_V	0.516	0.24
590_I	791_E	0.515	0.24
380_I	384_I	0.515	0.24
483_S	702_S	0.515	0.24
472_A	637_G	0.514	0.24
628_I	631_T	0.513	0.24
736_L	773_N	0.513	0.24
365_P	430_T	0.513	0.24
459_Q	470_G	0.511	0.24
702_S	706_R	0.511	0.24
732_Y	775_M	0.510	0.24
360_I	373_Q	0.510	0.24
482_E	763_G	0.509	0.24
498_Q	513_N	0.507	0.24
456_E	525_V	0.507	0.24
698_V	736_L	0.507	0.24
112_L	238_L	0.506	0.24
29_V	74_I	0.506	0.24
177_D	180_D	0.506	0.24
458_N	572_R	0.506	0.24
513_N	702_S	0.505	0.24
246_D	250_L	0.505	0.24
746_S	766_C	0.505	0.24
510_Q	583_T	0.505	0.24
425_Q	433_F	0.505	0.24
423_R	428_P	0.505	0.24
510_Q	643_A	0.505	0.24
489_A	636_Y	0.504	0.23
706_R	721_I	0.504	0.23
131_Y	146_Y	0.503	0.23
132_L	142_P	0.502	0.23
479_S	770_N	0.502	0.23
151_Q	166_L	0.502	0.23
115_G	131_Y	0.502	0.23
149_N	169_G	0.501	0.23
764_Q	777_E	0.501	0.23
705_I	713_L	0.500	0.23
478_Q	646_L	0.500	0.23

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.364	100	0.701	Contact Map
4gczA	2	0.373	100	0.704	Contact Map
3a0rA	2	0.3371	100	0.721	Contact Map
4r3aA	1	0.3135	100	0.764	Contact Map
4q20A	2	0.2506	100	0.768	Contact Map
4mpcA	2	0.3584	100	0.768	Contact Map
2c2aA	2	0.2528	100	0.769	Contact Map
4e01A	3	0.3169	100	0.77	Contact Map
2q8gA	2	0.3584	100	0.774	Contact Map
3jz3A	2	0.1753	100	0.776	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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