GNTT - ECOLI - GREMLIN Contacts

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GNTT - High-affinity gluconate transporter

UniProt:	P39835	Sequences: MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLDKVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVVLTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGPTAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEEMPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFTFGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNISPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSHVNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12380
Length:	438 (415)
Sequences:	5763 (3884)
Seq/√Len:	190.7

ECOLI - GNTT GNTP YJHF GNTU IDNT YGBN DSDX YFCC DCUC
BACSU - GNTP YOJA YXJC CITM YCGA CITN YRAO
HALSA - Q9HNF6 Q9HNR2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
262_P	266_T	3.907	1.00
332_T	335_S	3.761	1.00
294_S	297_K	3.705	1.00
284_S	287_Q	3.465	1.00
87_T	91_K	3.154	1.00
9_G	312_F	3.110	1.00
12_L	34_A	3.096	1.00
314_Q	318_D	2.934	1.00
323_K	327_S	2.907	1.00
190_G	193_Y	2.903	1.00
262_P	265_A	2.872	1.00
9_G	35_V	2.855	1.00
231_V	272_I	2.833	1.00
77_D	291_T	2.825	1.00
408_T	411_E	2.815	1.00
11_I	15_L	2.751	1.00
222_F	226_V	2.751	1.00
338_L	428_L	2.630	1.00
221_S	224_V	2.594	1.00
42_P	45_K	2.526	1.00
87_T	222_F	2.510	1.00
49_S	318_D	2.492	1.00
421_T	425_V	2.490	1.00
87_T	90_A	2.449	1.00
425_V	429_V	2.408	1.00
341_W	424_S	2.406	1.00
15_L	19_R	2.406	1.00
180_I	184_P	2.370	1.00
429_V	433_L	2.328	1.00
327_S	330_H	2.292	1.00
77_D	287_Q	2.268	1.00
223_G	227_W	2.264	1.00
196_V	199_G	2.188	1.00
82_Q	86_T	2.172	1.00
193_Y	196_V	2.127	1.00
344_A	361_A	2.112	1.00
193_Y	197_L	2.084	1.00
52_A	56_G	2.067	1.00
232_P	236_M	1.991	1.00
48_G	52_A	1.981	1.00
45_K	48_G	1.959	1.00
194_A	197_L	1.945	1.00
110_F	113_F	1.854	1.00
414_K	418_M	1.815	1.00
237_A	240_A	1.790	1.00
228_T	232_P	1.789	1.00
222_F	225_S	1.786	1.00
167_F	383_V	1.784	1.00
192_V	196_V	1.746	1.00
140_G	405_F	1.742	1.00
340_A	383_V	1.723	1.00
324_Y	328_M	1.702	1.00
190_G	194_A	1.701	1.00
369_I	379_M	1.697	1.00
12_L	31_V	1.691	1.00
101_V	104_T	1.671	1.00
345_A	389_I	1.653	1.00
225_S	228_T	1.651	1.00
42_P	46_V	1.647	1.00
239_R	243_E	1.644	1.00
73_K	77_D	1.624	1.00
271_L	275_F	1.620	1.00
349_I	390_F	1.617	1.00
418_M	422_I	1.601	1.00
189_A	193_Y	1.595	1.00
163_I	358_A	1.589	1.00
373_G	376_P	1.588	1.00
200_I	204_I	1.584	1.00
113_F	116_V	1.578	1.00
262_P	267_L	1.570	1.00
12_L	16_L	1.570	1.00
114_Y	117_G	1.562	1.00
266_T	270_V	1.561	1.00
200_I	203_P	1.550	1.00
34_A	38_M	1.535	1.00
266_T	269_A	1.534	1.00
130_A	136_L	1.526	1.00
287_Q	290_D	1.523	1.00
188_L	192_V	1.507	1.00
54_V	62_A	1.505	1.00
174_T	377_E	1.503	1.00
5_I	38_M	1.503	1.00
240_A	243_E	1.498	1.00
190_G	197_L	1.495	1.00
229_S	236_M	1.494	1.00
94_K	131_S	1.489	1.00
188_L	426_C	1.482	1.00
83_R	87_T	1.480	1.00
105_G	108_V	1.476	1.00
265_A	270_V	1.475	1.00
176_L	180_I	1.474	1.00
99_W	191_P	1.472	1.00
223_G	226_V	1.453	1.00
104_T	108_V	1.451	1.00
432_L	435_N	1.451	1.00
263_V	267_L	1.441	1.00
13_L	31_V	1.440	1.00
206_E	210_S	1.432	1.00
396_P	400_L	1.418	1.00
290_D	294_S	1.414	1.00
409_I	413_I	1.397	1.00
396_P	401_F	1.396	1.00
69_A	292_L	1.390	1.00
174_T	380_V	1.381	1.00
313_K	317_V	1.376	1.00
101_V	108_V	1.376	1.00
39_Q	42_P	1.375	1.00
227_W	231_V	1.370	1.00
31_V	34_A	1.367	1.00
199_G	203_P	1.363	1.00
269_A	273_A	1.347	1.00
192_V	195_R	1.344	1.00
224_V	227_W	1.343	1.00
152_G	388_V	1.342	1.00
286_D	290_D	1.337	1.00
272_I	276_T	1.335	1.00
238_M	242_A	1.322	1.00
201_D	205_P	1.322	1.00
73_K	291_T	1.314	1.00
57_T	310_G	1.313	1.00
385_S	431_C	1.309	1.00
220_P	224_V	1.297	1.00
22_M	27_A	1.297	1.00
235_L	268_I	1.287	1.00
77_D	294_S	1.285	1.00
101_V	105_G	1.276	1.00
49_S	314_Q	1.276	1.00
265_A	273_A	1.274	1.00
236_M	240_A	1.270	1.00
389_I	424_S	1.259	1.00
410_G	414_K	1.257	1.00
101_V	107_T	1.249	1.00
228_T	236_M	1.249	1.00
104_T	107_T	1.242	1.00
370_A	376_P	1.240	1.00
382_A	386_G	1.237	1.00
198_K	202_K	1.229	1.00
261_D	266_T	1.226	1.00
78_C	277_F	1.224	1.00
338_L	432_L	1.215	1.00
236_M	239_R	1.215	1.00
102_V	105_G	1.214	1.00
81_A	85_A	1.213	1.00
191_P	195_R	1.211	1.00
110_F	114_Y	1.206	1.00
353_S	356_V	1.203	1.00
176_L	179_T	1.200	1.00
419_L	423_I	1.192	1.00
264_M	268_I	1.190	1.00
195_R	198_K	1.185	1.00
306_I	396_P	1.184	1.00
372_T	376_P	1.183	1.00
111_A	115_E	1.170	1.00
242_A	246_L	1.163	1.00
171_M	175_L	1.157	1.00
115_E	396_P	1.156	1.00
109_G	117_G	1.145	1.00
270_V	274_M	1.140	1.00
199_G	202_K	1.138	1.00
274_M	278_G	1.137	1.00
86_T	131_S	1.136	1.00
231_V	235_L	1.127	1.00
273_A	277_F	1.126	1.00
221_S	225_S	1.124	1.00
225_S	232_P	1.121	1.00
219_M	223_G	1.118	1.00
266_T	274_M	1.112	1.00
263_V	266_T	1.112	1.00
179_T	183_I	1.111	1.00
181_L	434_L	1.102	1.00
427_G	431_C	1.102	1.00
430_G	434_L	1.101	1.00
235_L	239_R	1.098	1.00
86_T	90_A	1.096	1.00
53_G	314_Q	1.090	1.00
232_P	235_L	1.087	1.00
192_V	197_L	1.086	1.00
260_G	273_A	1.085	1.00
378_L	434_L	1.085	1.00
320_G	323_K	1.085	1.00
397_G	401_F	1.084	1.00
41_M	49_S	1.083	1.00
171_M	176_L	1.081	1.00
270_V	276_T	1.080	1.00
71_L	269_A	1.077	1.00
389_I	421_T	1.077	1.00
175_L	178_G	1.075	1.00
115_E	306_I	1.075	1.00
274_M	277_F	1.071	1.00
109_G	115_E	1.065	1.00
261_D	264_M	1.063	1.00
234_V	238_M	1.063	1.00
385_S	427_G	1.062	1.00
74_M	273_A	1.061	1.00
402_K	409_I	1.059	1.00
265_A	276_T	1.055	1.00
222_F	227_W	1.051	1.00
113_F	117_G	1.051	1.00
118_F	404_Y	1.048	1.00
241_I	245_I	1.045	1.00
265_A	269_A	1.042	1.00
80_G	225_S	1.041	1.00
381_I	431_C	1.040	1.00
191_P	196_V	1.039	1.00
191_P	194_A	1.035	1.00
35_V	38_M	1.035	1.00
64_I	306_I	1.034	1.00
177_Y	381_I	1.031	1.00
201_D	204_I	1.030	1.00
391_S	395_D	1.028	1.00
261_D	265_A	1.025	1.00
82_Q	217_E	1.022	1.00
239_R	244_M	1.021	1.00
182_A	186_V	1.020	1.00
233_V	237_A	1.020	1.00
141_V	145_A	1.019	1.00
45_K	49_S	1.014	1.00
341_W	428_L	1.013	1.00
402_K	412_T	1.012	1.00
103_L	107_T	1.010	1.00
411_E	414_K	1.008	1.00
6_V	10_V	1.006	1.00
52_A	55_G	1.001	1.00
166_I	362_G	0.999	1.00
206_E	209_Y	0.999	1.00
164_A	167_F	0.999	1.00
181_L	430_G	0.997	0.99
239_R	242_A	0.997	0.99
50_I	311_A	0.986	0.99
219_M	222_F	0.985	0.99
243_E	246_L	0.985	0.99
222_F	236_M	0.983	0.99
220_P	225_S	0.981	0.99
27_A	31_V	0.980	0.99
183_I	187_I	0.976	0.99
162_A	359_I	0.972	0.99
220_P	234_V	0.964	0.99
111_A	116_V	0.961	0.99
197_L	200_I	0.957	0.99
226_V	230_L	0.954	0.99
116_V	119_V	0.948	0.99
225_S	236_M	0.945	0.99
9_G	34_A	0.945	0.99
44_D	48_G	0.943	0.99
332_T	337_L	0.933	0.99
16_L	27_A	0.932	0.99
199_G	204_I	0.932	0.99
420_E	423_I	0.931	0.99
189_A	423_I	0.927	0.99
178_G	181_L	0.927	0.99
224_V	228_T	0.925	0.99
264_M	267_L	0.925	0.99
227_W	234_V	0.925	0.99
40_G	43_L	0.919	0.99
40_G	45_K	0.917	0.99
170_D	173_K	0.915	0.99
260_G	265_A	0.910	0.99
283_R	287_Q	0.908	0.99
314_Q	317_V	0.904	0.99
349_I	389_I	0.904	0.99
222_F	228_T	0.902	0.99
220_P	232_P	0.901	0.99
150_T	157_H	0.895	0.99
175_L	180_I	0.895	0.99
267_L	271_L	0.889	0.99
271_L	277_F	0.888	0.99
187_I	192_V	0.887	0.99
150_T	154_L	0.887	0.99
354_A	391_S	0.887	0.99
228_T	276_T	0.885	0.99
83_R	225_S	0.881	0.99
224_V	232_P	0.880	0.99
232_P	239_R	0.879	0.99
262_P	269_A	0.879	0.99
358_A	387_S	0.878	0.99
417_S	421_T	0.873	0.99
110_F	115_E	0.872	0.99
390_F	417_S	0.872	0.99
240_A	245_I	0.870	0.99
222_F	230_L	0.865	0.99
101_V	106_F	0.863	0.99
71_L	270_V	0.863	0.99
68_G	295_S	0.861	0.99
351_L	360_T	0.860	0.98
96_H	100_A	0.858	0.98
241_I	244_M	0.857	0.98
174_T	178_G	0.854	0.98
205_P	209_Y	0.854	0.98
109_G	113_F	0.852	0.98
391_S	416_W	0.851	0.98
283_R	288_I	0.849	0.98
216_E	219_M	0.848	0.98
416_W	420_E	0.847	0.98
214_F	217_E	0.841	0.98
407_L	411_E	0.839	0.98
202_K	205_P	0.839	0.98
83_R	222_F	0.839	0.98
171_M	180_I	0.836	0.98
348_R	395_D	0.829	0.98
96_H	106_F	0.829	0.98
412_T	416_W	0.827	0.98
428_L	432_L	0.825	0.98
111_A	114_Y	0.823	0.98
174_T	177_Y	0.820	0.98
102_V	106_F	0.820	0.98
287_Q	291_T	0.818	0.98
221_S	226_V	0.814	0.98
133_N	199_G	0.814	0.98
237_A	241_I	0.812	0.98
96_H	108_V	0.810	0.98
266_T	273_A	0.809	0.98
73_K	294_S	0.808	0.98
221_S	228_T	0.808	0.98
148_S	420_E	0.806	0.98
16_L	22_M	0.805	0.98
240_A	244_M	0.804	0.98
93_G	100_A	0.804	0.98
266_T	277_F	0.803	0.98
5_I	9_G	0.802	0.98
25_F	304_L	0.801	0.98
171_M	178_G	0.800	0.98
7_A	11_I	0.800	0.98
35_V	312_F	0.799	0.98
230_L	237_A	0.799	0.98
264_M	269_A	0.799	0.98
261_D	270_V	0.798	0.98
114_Y	397_G	0.797	0.98
164_A	170_D	0.797	0.98
53_G	56_G	0.796	0.98
215_S	219_M	0.796	0.98
366_A	370_A	0.796	0.98
344_A	357_A	0.795	0.97
274_M	292_L	0.791	0.97
332_T	336_P	0.791	0.97
153_F	427_G	0.788	0.97
348_R	354_A	0.788	0.97
377_E	381_I	0.787	0.97
263_V	273_A	0.787	0.97
52_A	318_D	0.787	0.97
378_L	431_C	0.786	0.97
232_P	237_A	0.785	0.97
220_P	223_G	0.784	0.97
220_P	228_T	0.783	0.97
226_V	232_P	0.776	0.97
231_V	234_V	0.776	0.97
182_A	185_T	0.774	0.97
222_F	229_S	0.773	0.97
423_I	427_G	0.771	0.97
340_A	365_A	0.768	0.97
221_S	227_W	0.768	0.97
375_S	378_L	0.767	0.97
214_F	218_E	0.766	0.97
345_A	424_S	0.764	0.97
35_V	315_V	0.761	0.97
129_A	139_V	0.759	0.97
141_V	415_S	0.758	0.97
177_Y	180_I	0.757	0.97
103_L	106_F	0.756	0.97
264_M	270_V	0.756	0.97
391_S	397_G	0.755	0.97
115_E	119_V	0.754	0.97
273_A	276_T	0.754	0.97
12_L	19_R	0.753	0.97
357_A	395_D	0.749	0.96
237_A	244_M	0.746	0.96
351_L	356_V	0.746	0.96
417_S	424_S	0.742	0.96
264_M	277_F	0.741	0.96
262_P	273_A	0.739	0.96
102_V	186_V	0.737	0.96
173_K	176_L	0.737	0.96
223_G	228_T	0.737	0.96
48_G	51_K	0.735	0.96
188_L	191_P	0.735	0.96
357_A	361_A	0.735	0.96
233_V	236_M	0.734	0.96
102_V	108_V	0.734	0.96
299_I	303_L	0.731	0.96
193_Y	422_I	0.727	0.96
160_P	164_A	0.727	0.96
12_L	15_L	0.727	0.96
221_S	232_P	0.725	0.96
63_L	67_F	0.724	0.96
117_G	147_L	0.724	0.96
258_F	261_D	0.723	0.96
211_A	215_S	0.715	0.95
109_G	112_L	0.715	0.95
232_P	240_A	0.714	0.95
354_A	387_S	0.714	0.95
111_A	117_G	0.712	0.95
91_K	94_K	0.712	0.95
262_P	270_V	0.711	0.95
112_L	115_E	0.711	0.95
40_G	44_D	0.710	0.95
381_I	385_S	0.709	0.95
348_R	357_A	0.706	0.95
100_A	107_T	0.704	0.95
26_I	270_V	0.704	0.95
308_G	312_F	0.703	0.95
415_S	418_M	0.703	0.95
223_G	237_A	0.701	0.95
8_I	12_L	0.700	0.95
200_I	205_P	0.698	0.95
284_S	288_I	0.697	0.95
47_I	51_K	0.695	0.95
137_L	203_P	0.695	0.95
73_K	76_A	0.692	0.94
185_T	430_G	0.692	0.94
43_L	46_V	0.691	0.94
185_T	189_A	0.691	0.94
88_L	92_F	0.691	0.94
410_G	413_I	0.690	0.94
348_R	391_S	0.687	0.94
189_A	196_V	0.687	0.94
15_L	18_I	0.684	0.94
80_G	83_R	0.683	0.94
275_F	278_G	0.682	0.94
329_M	343_I	0.682	0.94
177_Y	377_E	0.680	0.94
109_G	150_T	0.680	0.94
16_L	30_L	0.679	0.94
315_V	318_D	0.678	0.94
37_L	43_L	0.678	0.94
369_I	372_T	0.677	0.94
173_K	377_E	0.677	0.94
166_I	363_G	0.676	0.94
109_G	116_V	0.675	0.94
134_I	138_Y	0.674	0.94
345_A	390_F	0.671	0.94
126_F	136_L	0.670	0.93
184_P	430_G	0.669	0.93
39_Q	43_L	0.669	0.93
94_K	132_A	0.669	0.93
32_A	36_G	0.669	0.93
216_E	234_V	0.668	0.93
238_M	243_E	0.668	0.93
148_S	388_V	0.666	0.93
223_G	234_V	0.666	0.93
213_T	216_E	0.665	0.93
340_A	379_M	0.664	0.93
10_V	13_L	0.663	0.93
293_V	297_K	0.661	0.93
138_Y	142_P	0.660	0.93
278_G	288_I	0.659	0.93
227_W	230_L	0.657	0.93
263_V	271_L	0.655	0.93
277_F	288_I	0.655	0.93
91_K	95_K	0.654	0.93
86_T	219_M	0.652	0.93
84_I	225_S	0.651	0.92
216_E	221_S	0.646	0.92
63_L	66_G	0.646	0.92
172_G	176_L	0.646	0.92
263_V	270_V	0.645	0.92
426_C	430_G	0.645	0.92
33_L	264_M	0.645	0.92
229_S	232_P	0.642	0.92
348_R	387_S	0.642	0.92
367_P	372_T	0.641	0.92
96_H	107_T	0.640	0.92
184_P	188_L	0.639	0.92
239_R	245_I	0.634	0.91
116_V	159_G	0.633	0.91
262_P	275_F	0.631	0.91
99_W	103_L	0.631	0.91
96_H	101_V	0.630	0.91
144_A	397_G	0.630	0.91
108_V	182_A	0.629	0.91
5_I	34_A	0.627	0.91
267_L	277_F	0.626	0.91
50_I	53_G	0.626	0.91
135_P	200_I	0.625	0.91
333_N	339_M	0.625	0.91
238_M	244_M	0.623	0.91
198_K	201_D	0.621	0.91
114_Y	118_F	0.621	0.91
396_P	399_W	0.621	0.91
23_N	26_I	0.620	0.91
333_N	337_L	0.620	0.91
52_A	314_Q	0.619	0.90
205_P	208_L	0.619	0.90
231_V	269_A	0.619	0.90
33_L	211_A	0.619	0.90
336_P	379_M	0.618	0.90
216_E	220_P	0.617	0.90
129_A	134_I	0.613	0.90
100_A	106_F	0.613	0.90
106_F	110_F	0.613	0.90
96_H	99_W	0.612	0.90
229_S	233_V	0.610	0.90
154_L	157_H	0.609	0.90
228_T	235_L	0.609	0.90
345_A	349_I	0.607	0.90
222_F	232_P	0.606	0.90
96_H	102_V	0.606	0.90
259_L	263_V	0.605	0.89
273_A	278_G	0.603	0.89
431_C	435_N	0.603	0.89
218_E	221_S	0.601	0.89
125_V	129_A	0.600	0.89
261_D	269_A	0.599	0.89
263_V	277_F	0.597	0.89
218_E	223_G	0.597	0.89
234_V	239_R	0.596	0.89
49_S	53_G	0.595	0.89
228_T	231_V	0.595	0.89
426_C	429_V	0.594	0.89
221_S	236_M	0.594	0.89
223_G	245_I	0.593	0.89
265_A	277_F	0.590	0.88
25_F	29_V	0.589	0.88
367_P	371_T	0.588	0.88
174_T	180_I	0.588	0.88
223_G	232_P	0.588	0.88
227_W	276_T	0.585	0.88
6_V	9_G	0.584	0.88
266_T	278_G	0.584	0.88
344_A	387_S	0.583	0.88
327_S	331_E	0.583	0.88
164_A	174_T	0.582	0.88
305_I	359_I	0.581	0.88
265_A	268_I	0.580	0.87
34_A	37_L	0.579	0.87
324_Y	327_S	0.576	0.87
151_H	155_P	0.574	0.87
390_F	413_I	0.574	0.87
340_A	344_A	0.571	0.87
181_L	185_T	0.571	0.87
392_H	420_E	0.571	0.87
187_I	191_P	0.569	0.86
102_V	107_T	0.568	0.86
356_V	360_T	0.568	0.86
349_I	417_S	0.568	0.86
430_G	433_L	0.566	0.86
227_W	233_V	0.566	0.86
193_Y	418_M	0.566	0.86
31_V	35_V	0.565	0.86
225_S	229_S	0.565	0.86
372_T	375_S	0.564	0.86
354_A	396_P	0.563	0.86
274_M	288_I	0.561	0.86
110_F	150_T	0.561	0.86
145_A	416_W	0.560	0.86
220_P	227_W	0.558	0.85
171_M	182_A	0.558	0.85
221_S	238_M	0.558	0.85
109_G	114_Y	0.557	0.85
227_W	235_L	0.557	0.85
151_H	156_P	0.556	0.85
292_L	295_S	0.556	0.85
102_V	142_P	0.556	0.85
270_V	277_F	0.555	0.85
265_A	271_L	0.552	0.85
112_L	117_G	0.551	0.85
230_L	234_V	0.551	0.85
145_A	419_L	0.550	0.85
262_P	268_I	0.548	0.84
215_S	331_E	0.548	0.84
259_L	264_M	0.548	0.84
9_G	39_Q	0.548	0.84
122_L	405_F	0.545	0.84
140_G	407_L	0.543	0.84
29_V	67_F	0.543	0.84
133_N	201_D	0.543	0.84
153_F	385_S	0.542	0.84
112_L	266_T	0.542	0.84
160_P	354_A	0.540	0.83
190_G	196_V	0.539	0.83
178_G	184_P	0.536	0.83
32_A	315_V	0.536	0.83
113_F	159_G	0.533	0.83
8_I	34_A	0.530	0.82
180_I	189_A	0.530	0.82
141_V	419_L	0.529	0.82
190_G	195_R	0.528	0.82
230_L	236_M	0.527	0.82
379_M	411_E	0.525	0.82
146_A	150_T	0.524	0.82
188_L	194_A	0.524	0.82
272_I	275_F	0.522	0.81
165_T	170_D	0.520	0.81
90_A	198_K	0.520	0.81
196_V	202_K	0.519	0.81
278_G	281_R	0.519	0.81
185_T	426_C	0.518	0.81
65_M	68_G	0.516	0.81
229_S	235_L	0.514	0.80
118_F	122_L	0.514	0.80
9_G	13_L	0.513	0.80
225_S	239_R	0.513	0.80
37_L	41_M	0.512	0.80
296_I	300_A	0.512	0.80
157_H	358_A	0.512	0.80
41_M	45_K	0.510	0.80
5_I	321_V	0.510	0.80
27_A	30_L	0.510	0.80
36_G	46_V	0.510	0.80
117_G	157_H	0.510	0.80
212_K	215_S	0.509	0.80
203_P	206_E	0.508	0.80
223_G	230_L	0.508	0.80
391_S	420_E	0.508	0.80
262_P	277_F	0.508	0.80
221_S	229_S	0.507	0.79
242_A	245_I	0.506	0.79
13_L	17_M	0.506	0.79
100_A	108_V	0.506	0.79
90_A	93_G	0.505	0.79
218_E	222_F	0.505	0.79
5_I	31_V	0.504	0.79
258_F	262_P	0.504	0.79
148_S	397_G	0.504	0.79
290_D	293_V	0.504	0.79
144_A	392_H	0.503	0.79
390_F	421_T	0.503	0.79
226_V	236_M	0.502	0.79
361_A	383_V	0.502	0.79
224_V	272_I	0.502	0.79
169_A	174_T	0.502	0.79
21_K	27_A	0.501	0.79
334_I	338_L	0.500	0.79
30_L	34_A	0.500	0.79

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r1iA	2	0.9795	100	0.556	Contact Map
4r0cA	3	0.9726	100	0.569	Contact Map
4f35D	2	0.9018	100	0.609	Contact Map
4pd6A	3	0.7671	81.4	0.94	Contact Map
3qe7A	2	0.4475	58.3	0.949	Contact Map
2cfqA	1	0.8265	54.2	0.951	Contact Map
4dx5A	3	0.3584	49.5	0.952	Contact Map
3aqpA	1	0.3311	44.2	0.954	Contact Map
3qnqA	2	0.4658	31.1	0.957	Contact Map
2nwlA	3	0.742	23.2	0.96	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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