GARD - ECOLI - GREMLIN Contacts

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GARD - D-galactarate dehydratase

UniProt:	P39829	Sequences: MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12522
Length:	523 (489)
Sequences:	1217 (799)
Seq/√Len:	36.1

ECOLI - GARD UXAA
BACSU - GARD UXAA
SULSO - Q97YR2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
495_D	500_K	6.599	1.00
121_E	276_T	5.372	1.00
124_R	281_E	4.874	1.00
279_A	494_L	4.043	1.00
124_R	275_E	3.936	1.00
76_A	80_I	3.923	1.00
338_N	341_V	3.869	1.00
339_E	343_K	3.808	1.00
33_L	45_L	3.771	1.00
307_S	317_V	3.768	1.00
124_R	277_C	3.593	1.00
25_A	57_L	3.543	1.00
59_D	82_R	3.316	1.00
318_M	431_I	3.297	1.00
303_V	437_T	3.197	1.00
281_E	408_R	3.144	1.00
47_E	84_S	3.123	1.00
458_T	462_N	3.056	1.00
61_P	64_G	3.043	1.00
504_F	507_Q	3.033	1.00
415_T	429_S	3.030	1.00
471_N	477_T	2.946	1.00
470_I	489_L	2.897	1.00
61_P	79_A	2.849	1.00
45_L	55_V	2.759	1.00
62_A	79_A	2.759	1.00
343_K	347_E	2.689	1.00
66_I	91_V	2.661	1.00
118_Y	491_H	2.659	1.00
455_A	468_M	2.641	1.00
130_V	277_C	2.631	1.00
59_D	81_P	2.597	1.00
14_F	29_N	2.574	1.00
316_T	411_I	2.548	1.00
56_A	80_I	2.485	1.00
81_P	84_S	2.434	1.00
205_G	269_L	2.431	1.00
35_A	48_H	2.414	1.00
166_N	270_N	2.391	1.00
123_Y	131_G	2.375	1.00
354_N	358_M	2.360	1.00
433_V	493_I	2.284	0.99
491_H	495_D	2.284	0.99
471_N	474_T	2.273	0.99
277_C	281_E	2.253	0.99
60_I	76_A	2.212	0.99
60_I	80_I	2.164	0.99
452_I	496_V	2.146	0.99
27_I	33_L	2.143	0.99
435_V	454_M	2.125	0.99
474_T	488_K	2.105	0.99
75_Y	94_P	2.091	0.99
29_N	37_T	2.069	0.99
133_K	506_D	2.052	0.99
302_A	489_L	2.033	0.99
454_M	472_A	2.023	0.99
149_V	211_I	2.022	0.99
17_K	41_D	2.018	0.99
118_Y	494_L	2.015	0.98
492_F	500_K	1.996	0.98
34_K	48_H	1.993	0.98
23_N	60_I	1.989	0.98
475_I	482_I	1.965	0.98
121_E	500_K	1.939	0.98
59_D	79_A	1.931	0.98
45_L	49_I	1.924	0.98
257_D	260_Q	1.891	0.98
60_I	64_G	1.890	0.98
302_A	475_I	1.889	0.98
492_F	495_D	1.889	0.98
427_V	446_L	1.886	0.98
458_T	471_N	1.872	0.98
350_E	353_D	1.862	0.97
152_V	258_I	1.851	0.97
337_V	396_V	1.836	0.97
137_G	204_F	1.830	0.97
268_K	271_Q	1.822	0.97
459_E	463_R	1.821	0.97
284_V	306_A	1.807	0.97
396_V	407_K	1.796	0.97
485_V	488_K	1.774	0.97
199_S	223_L	1.772	0.97
206_G	265_H	1.771	0.97
344_R	397_E	1.771	0.97
23_N	58_L	1.763	0.96
33_L	55_V	1.757	0.96
236_E	264_R	1.750	0.96
397_E	407_K	1.747	0.96
309_L	487_W	1.735	0.96
152_V	255_V	1.723	0.96
34_K	37_T	1.716	0.96
459_E	462_N	1.714	0.96
15_Y	25_A	1.706	0.96
492_F	496_V	1.684	0.95
420_F	444_Y	1.681	0.95
46_I	81_P	1.681	0.95
474_T	485_V	1.670	0.95
461_A	468_M	1.657	0.95
136_L	262_A	1.655	0.95
156_I	259_L	1.653	0.95
268_K	272_R	1.640	0.95
423_G	446_L	1.627	0.94
446_L	451_V	1.623	0.94
481_T	484_E	1.601	0.94
132_T	432_T	1.587	0.94
455_A	461_A	1.586	0.94
337_V	341_V	1.575	0.93
309_L	486_G	1.572	0.93
470_I	492_F	1.566	0.93
14_F	37_T	1.564	0.93
310_L	315_A	1.548	0.93
180_G	217_K	1.546	0.93
58_L	64_G	1.527	0.92
344_R	403_Q	1.513	0.92
46_I	84_S	1.511	0.92
337_V	407_K	1.511	0.92
71_E	331_L	1.500	0.92
287_Q	426_Q	1.482	0.91
140_T	149_V	1.479	0.91
306_A	310_L	1.477	0.91
118_Y	279_A	1.455	0.90
78_R	84_S	1.450	0.90
126_A	231_Q	1.449	0.90
305_Y	483_E	1.449	0.90
427_V	449_V	1.445	0.90
154_K	157_E	1.428	0.89
91_V	377_A	1.422	0.89
452_I	492_F	1.406	0.89
199_S	210_V	1.405	0.89
320_S	426_Q	1.382	0.88
30_D	51_Q	1.377	0.88
462_N	465_F	1.367	0.87
129_S	404_R	1.364	0.87
305_Y	482_I	1.360	0.87
51_Q	459_E	1.357	0.87
336_A	345_L	1.355	0.87
341_V	397_E	1.352	0.87
313_C	490_F	1.345	0.86
23_N	67_I	1.332	0.86
393_S	396_V	1.330	0.86
302_A	486_G	1.325	0.85
26_I	68_R	1.324	0.85
487_W	491_H	1.313	0.85
285_G	434_Q	1.308	0.85
260_Q	264_R	1.305	0.85
278_P	281_E	1.292	0.84
136_L	269_L	1.291	0.84
266_L	270_N	1.286	0.84
119_T	276_T	1.286	0.84
192_I	218_L	1.283	0.84
38_R	44_E	1.256	0.82
30_D	48_H	1.255	0.82
400_S	403_Q	1.252	0.82
25_A	55_V	1.248	0.82
345_L	412_Y	1.247	0.82
77_V	92_V	1.245	0.82
318_M	405_P	1.240	0.81
180_G	369_P	1.237	0.81
156_I	170_V	1.235	0.81
309_L	490_F	1.215	0.80
443_P	510_L	1.213	0.80
474_T	479_E	1.211	0.80
118_Y	490_F	1.206	0.80
129_S	283_V	1.205	0.80
399_L	411_I	1.198	0.79
270_N	273_Q	1.195	0.79
465_F	504_F	1.191	0.79
56_A	60_I	1.174	0.78
124_R	130_V	1.173	0.78
429_S	456_T	1.169	0.77
337_V	394_A	1.168	0.77
88_E	381_E	1.165	0.77
257_D	261_I	1.157	0.77
286_M	319_F	1.153	0.76
200_L	404_R	1.148	0.76
456_T	475_I	1.147	0.76
379_V	386_S	1.146	0.76
328_A	387_I	1.143	0.76
135_L	169_G	1.142	0.76
121_E	124_R	1.142	0.76
123_Y	272_R	1.141	0.76
302_A	470_I	1.141	0.76
47_E	85_W	1.139	0.76
87_D	377_A	1.128	0.75
17_K	25_A	1.120	0.74
155_I	259_L	1.120	0.74
286_M	303_V	1.119	0.74
287_Q	423_G	1.118	0.74
37_T	45_L	1.112	0.74
62_A	78_R	1.107	0.73
328_A	384_L	1.097	0.73
152_V	211_I	1.096	0.73
354_N	357_N	1.095	0.73
236_E	261_I	1.093	0.72
120_F	130_V	1.092	0.72
461_A	471_N	1.085	0.72
80_I	86_I	1.083	0.72
331_L	384_L	1.081	0.72
284_V	493_I	1.081	0.72
65_E	72_V	1.079	0.71
415_T	425_Q	1.075	0.71
154_K	158_R	1.065	0.70
65_E	94_P	1.058	0.70
144_C	215_C	1.057	0.70
276_T	494_L	1.055	0.70
461_A	465_F	1.051	0.69
45_L	48_H	1.040	0.69
458_T	473_G	1.031	0.68
222_R	225_T	1.027	0.68
152_V	262_A	1.019	0.67
486_G	489_L	1.015	0.67
475_I	485_V	1.010	0.66
431_I	448_A	1.007	0.66
71_E	384_L	1.004	0.66
192_I	226_G	1.001	0.66
303_V	454_M	1.000	0.66
458_T	477_T	0.996	0.65
144_C	179_C	0.995	0.65
424_T	514_L	0.995	0.65
93_L	362_D	0.994	0.65
176_L	515_A	0.987	0.64
116_E	487_W	0.987	0.64
118_Y	313_C	0.981	0.64
179_C	215_C	0.979	0.64
14_F	28_V	0.977	0.64
17_K	57_L	0.977	0.64
152_V	259_L	0.976	0.64
287_Q	320_S	0.972	0.63
157_E	169_G	0.969	0.63
306_A	489_L	0.967	0.63
150_D	174_N	0.963	0.63
129_S	281_E	0.963	0.63
182_A	217_K	0.963	0.63
340_E	344_R	0.960	0.62
166_N	266_L	0.959	0.62
139_T	199_S	0.956	0.62
166_N	273_Q	0.952	0.62
338_N	491_H	0.950	0.61
333_T	346_L	0.949	0.61
124_R	408_R	0.948	0.61
298_T	476_A	0.946	0.61
194_T	197_N	0.946	0.61
65_E	75_Y	0.945	0.61
283_V	408_R	0.939	0.61
164_Y	270_N	0.939	0.61
132_T	433_V	0.936	0.60
503_T	506_D	0.935	0.60
30_D	34_K	0.934	0.60
198_I	448_A	0.934	0.60
387_I	422_C	0.928	0.60
501_K	507_Q	0.927	0.60
196_H	227_T	0.925	0.59
136_L	153_V	0.925	0.59
261_I	264_R	0.922	0.59
252_Q	466_D	0.919	0.59
435_V	493_I	0.917	0.59
30_D	50_P	0.911	0.58
491_H	494_L	0.909	0.58
138_I	153_V	0.909	0.58
275_E	281_E	0.900	0.57
306_A	317_V	0.898	0.57
86_I	91_V	0.896	0.57
462_N	471_N	0.893	0.57
183_I	217_K	0.891	0.57
356_L	464_W	0.888	0.56
452_I	493_I	0.886	0.56
253_S	256_E	0.886	0.56
126_A	233_I	0.884	0.56
479_E	488_K	0.883	0.56
61_P	81_P	0.882	0.56
258_I	513_Q	0.878	0.55
273_Q	471_N	0.876	0.55
223_L	227_T	0.876	0.55
294_F	476_A	0.876	0.55
121_E	277_C	0.874	0.55
333_T	349_M	0.872	0.55
361_T	364_S	0.871	0.55
35_A	45_L	0.871	0.55
427_V	434_Q	0.871	0.55
102_L	342_G	0.870	0.55
224_L	240_I	0.866	0.54
141_S	212_G	0.865	0.54
167_V	270_N	0.862	0.54
241_V	257_D	0.860	0.54
286_M	393_S	0.856	0.53
256_E	260_Q	0.852	0.53
231_Q	234_P	0.850	0.53
66_I	75_Y	0.849	0.53
423_G	444_Y	0.849	0.53
15_Y	45_L	0.848	0.53
351_W	414_A	0.847	0.53
458_T	461_A	0.843	0.52
156_I	266_L	0.842	0.52
284_V	433_V	0.839	0.52
120_F	497_A	0.839	0.52
326_R	353_D	0.834	0.52
190_V	519_P	0.832	0.51
343_K	350_E	0.832	0.51
285_G	307_S	0.830	0.51
316_T	397_E	0.826	0.51
397_E	406_T	0.825	0.51
405_P	411_I	0.825	0.51
136_L	206_G	0.822	0.51
201_N	432_T	0.822	0.51
302_A	485_V	0.813	0.50
217_K	361_T	0.812	0.50
55_V	58_L	0.806	0.49
504_F	508_W	0.806	0.49
121_E	273_Q	0.804	0.49
305_Y	392_K	0.803	0.49
129_S	408_R	0.798	0.48
220_P	224_L	0.797	0.48
368_S	379_V	0.796	0.48
356_L	363_R	0.795	0.48
339_E	342_G	0.793	0.48
400_S	414_A	0.793	0.48
482_I	486_G	0.792	0.48
147_G	150_D	0.791	0.48
49_I	130_V	0.790	0.48
71_E	330_H	0.790	0.48
21_T	70_G	0.788	0.48
66_I	76_A	0.787	0.47
452_I	503_T	0.786	0.47
56_A	76_A	0.785	0.47
47_E	55_V	0.784	0.47
93_L	367_P	0.783	0.47
279_A	490_F	0.780	0.47
399_L	429_S	0.780	0.47
127_D	432_T	0.779	0.47
137_G	342_G	0.779	0.47
217_K	369_P	0.777	0.47
148_V	251_F	0.776	0.47
15_Y	55_V	0.773	0.46
20_D	60_I	0.771	0.46
87_D	90_M	0.768	0.46
108_V	117_G	0.767	0.46
454_M	470_I	0.767	0.46
64_G	76_A	0.761	0.45
368_S	456_T	0.760	0.45
171_V	512_N	0.759	0.45
97_P	363_R	0.759	0.45
328_A	367_P	0.758	0.45
165_P	270_N	0.756	0.45
100_H	346_L	0.754	0.45
120_F	277_C	0.753	0.45
58_L	61_P	0.753	0.45
376_L	387_I	0.752	0.44
88_E	377_A	0.751	0.44
425_Q	516_V	0.751	0.44
374_G	440_R	0.751	0.44
205_G	272_R	0.749	0.44
194_T	428_A	0.748	0.44
315_A	433_V	0.747	0.44
192_I	390_S	0.747	0.44
404_R	429_S	0.745	0.44
212_G	220_P	0.745	0.44
282_L	497_A	0.745	0.44
66_I	78_R	0.743	0.44
298_T	478_G	0.741	0.44
455_A	458_T	0.741	0.44
316_T	405_P	0.738	0.43
182_A	362_D	0.736	0.43
303_V	489_L	0.735	0.43
347_E	351_W	0.735	0.43
444_Y	451_V	0.733	0.43
505_S	508_W	0.732	0.43
303_V	405_P	0.731	0.43
323_T	363_R	0.730	0.43
58_L	206_G	0.728	0.42
155_I	159_D	0.727	0.42
269_L	272_R	0.725	0.42
320_S	415_T	0.724	0.42
328_A	331_L	0.721	0.42
144_C	213_L	0.719	0.42
201_N	515_A	0.716	0.41
219_Q	415_T	0.715	0.41
330_H	334_P	0.715	0.41
199_S	235_V	0.715	0.41
79_A	461_A	0.713	0.41
120_F	498_S	0.713	0.41
29_N	33_L	0.713	0.41
88_E	91_V	0.712	0.41
41_D	57_L	0.709	0.41
262_A	266_L	0.709	0.41
126_A	232_A	0.708	0.41
472_A	485_V	0.705	0.40
49_I	113_P	0.705	0.40
316_T	415_T	0.705	0.40
444_Y	512_N	0.703	0.40
75_Y	96_A	0.703	0.40
29_N	34_K	0.703	0.40
307_S	393_S	0.702	0.40
271_Q	339_E	0.701	0.40
397_E	411_I	0.700	0.40
51_Q	294_F	0.700	0.40
251_F	255_V	0.699	0.40
148_V	255_V	0.699	0.40
309_L	312_R	0.697	0.40
286_M	456_T	0.697	0.40
20_D	127_D	0.697	0.40
49_I	55_V	0.694	0.40
342_G	379_V	0.694	0.40
191_P	516_V	0.692	0.39
194_T	402_G	0.692	0.39
56_A	91_V	0.691	0.39
489_L	492_F	0.690	0.39
117_G	278_P	0.690	0.39
179_C	213_L	0.689	0.39
402_G	429_S	0.689	0.39
201_N	433_V	0.688	0.39
487_W	490_F	0.685	0.39
196_H	200_L	0.683	0.39
78_R	89_S	0.683	0.39
318_M	413_A	0.682	0.39
159_D	263_E	0.681	0.38
427_V	451_V	0.681	0.38
212_G	384_L	0.679	0.38
131_G	202_P	0.678	0.38
454_M	489_L	0.678	0.38
119_T	278_P	0.678	0.38
34_K	45_L	0.678	0.38
59_D	338_N	0.678	0.38
277_C	432_T	0.677	0.38
306_A	493_I	0.677	0.38
118_Y	309_L	0.676	0.38
140_T	172_G	0.676	0.38
20_D	23_N	0.676	0.38
399_L	405_P	0.671	0.38
120_F	282_L	0.667	0.37
206_G	234_P	0.666	0.37
322_V	386_S	0.666	0.37
318_M	426_Q	0.662	0.37
225_T	406_T	0.661	0.37
225_T	491_H	0.660	0.37
28_V	202_P	0.658	0.37
434_Q	449_V	0.656	0.36
306_A	486_G	0.655	0.36
52_G	141_S	0.655	0.36
311_V	396_V	0.651	0.36
122_G	277_C	0.651	0.36
491_H	500_K	0.650	0.36
359_G	519_P	0.647	0.36
61_P	225_T	0.647	0.36
66_I	80_I	0.645	0.36
306_A	435_V	0.644	0.35
64_G	402_G	0.643	0.35
35_A	61_P	0.642	0.35
456_T	476_A	0.642	0.35
198_I	303_V	0.639	0.35
72_V	75_Y	0.639	0.35
43_L	57_L	0.639	0.35
16_I	28_V	0.638	0.35
336_A	341_V	0.638	0.35
205_G	210_V	0.638	0.35
33_L	211_I	0.631	0.34
212_G	381_E	0.630	0.34
220_P	242_S	0.630	0.34
276_T	279_A	0.629	0.34
302_A	306_A	0.629	0.34
233_I	268_K	0.628	0.34
72_V	471_N	0.628	0.34
387_I	434_Q	0.628	0.34
181_V	217_K	0.627	0.34
93_L	380_V	0.625	0.34
37_T	41_D	0.624	0.34
35_A	46_I	0.624	0.34
460_L	465_F	0.624	0.34
348_E	400_S	0.622	0.34
27_I	55_V	0.621	0.34
302_A	472_A	0.621	0.34
402_G	425_Q	0.620	0.34
164_Y	266_L	0.619	0.33
156_I	159_D	0.619	0.33
381_E	445_G	0.619	0.33
114_P	117_G	0.618	0.33
47_E	78_R	0.616	0.33
381_E	384_L	0.616	0.33
280_S	494_L	0.615	0.33
17_K	59_D	0.615	0.33
518_N	521_P	0.614	0.33
180_G	188_A	0.613	0.33
376_L	466_D	0.613	0.33
16_I	49_I	0.613	0.33
423_G	434_Q	0.612	0.33
113_P	117_G	0.611	0.33
131_G	272_R	0.611	0.33
367_P	379_V	0.610	0.33
132_T	455_A	0.609	0.33
37_T	338_N	0.609	0.33
369_P	464_W	0.608	0.33
183_I	361_T	0.608	0.33
58_L	62_A	0.607	0.33
60_I	82_R	0.607	0.33
80_I	383_A	0.605	0.32
147_G	512_N	0.605	0.32
26_I	55_V	0.603	0.32
405_P	457_R	0.602	0.32
228_D	231_Q	0.602	0.32
325_V	395_I	0.602	0.32
298_T	479_E	0.600	0.32
361_T	379_V	0.600	0.32
182_A	188_A	0.598	0.32
305_Y	310_L	0.598	0.32
475_I	486_G	0.598	0.32
144_C	244_Q	0.596	0.32
470_I	485_V	0.596	0.32
46_I	59_D	0.595	0.32
403_Q	406_T	0.595	0.32
418_S	521_P	0.595	0.32
23_N	94_P	0.594	0.32
344_R	347_E	0.591	0.31
90_M	457_R	0.590	0.31
145_V	413_A	0.590	0.31
43_L	55_V	0.589	0.31
33_L	37_T	0.589	0.31
216_E	244_Q	0.589	0.31
320_S	425_Q	0.589	0.31
284_V	403_Q	0.588	0.31
182_A	185_A	0.588	0.31
204_F	208_V	0.587	0.31
39_F	45_L	0.585	0.31
320_S	423_G	0.584	0.31
241_V	261_I	0.584	0.31
190_V	255_V	0.583	0.31
212_G	332_L	0.583	0.31
283_V	405_P	0.583	0.31
443_P	460_L	0.582	0.31
340_E	501_K	0.581	0.31
278_P	462_N	0.581	0.31
327_D	417_A	0.580	0.31
79_A	84_S	0.579	0.30
460_L	468_M	0.579	0.30
29_N	39_F	0.579	0.30
152_V	156_I	0.578	0.30
169_G	503_T	0.578	0.30
434_Q	510_L	0.578	0.30
163_K	166_N	0.577	0.30
425_Q	517_F	0.577	0.30
147_G	205_G	0.577	0.30
16_I	294_F	0.576	0.30
390_S	410_L	0.576	0.30
182_A	381_E	0.575	0.30
16_I	69_Y	0.574	0.30
286_M	317_V	0.574	0.30
26_I	51_Q	0.574	0.30
170_V	434_Q	0.574	0.30
415_T	421_V	0.573	0.30
45_L	50_P	0.572	0.30
329_I	417_A	0.572	0.30
443_P	464_W	0.572	0.30
215_C	244_Q	0.571	0.30
130_V	432_T	0.571	0.30
342_G	346_L	0.571	0.30
306_A	309_L	0.571	0.30
147_G	198_I	0.570	0.30
211_I	241_V	0.570	0.30
311_V	316_T	0.570	0.30
338_N	487_W	0.569	0.30
484_E	488_K	0.569	0.30
475_I	478_G	0.569	0.30
477_T	483_E	0.568	0.30
139_T	195_I	0.568	0.30
378_N	386_S	0.568	0.30
228_D	234_P	0.568	0.30
72_V	94_P	0.568	0.30
179_C	244_Q	0.568	0.30
15_Y	281_E	0.567	0.30
182_A	443_P	0.566	0.30
185_A	353_D	0.566	0.30
64_G	79_A	0.566	0.30
103_P	333_T	0.565	0.29
208_V	328_A	0.564	0.29
306_A	470_I	0.564	0.29
367_P	372_K	0.564	0.29
80_I	90_M	0.563	0.29
305_Y	487_W	0.563	0.29
68_R	293_A	0.562	0.29
201_N	456_T	0.561	0.29
142_V	179_C	0.560	0.29
179_C	308_D	0.560	0.29
282_L	287_Q	0.560	0.29
199_S	208_V	0.559	0.29
464_W	467_L	0.559	0.29
353_D	363_R	0.558	0.29
70_G	307_S	0.557	0.29
96_A	363_R	0.557	0.29
35_A	64_G	0.557	0.29
217_K	521_P	0.556	0.29
284_V	317_V	0.556	0.29
50_P	193_R	0.555	0.29
445_G	512_N	0.555	0.29
176_L	421_V	0.555	0.29
379_V	521_P	0.554	0.29
35_A	49_I	0.554	0.29
210_V	223_L	0.554	0.29
305_Y	486_G	0.554	0.29
213_L	244_Q	0.553	0.29
328_A	377_A	0.552	0.28
302_A	309_L	0.552	0.28
293_A	520_A	0.551	0.28
353_D	356_L	0.551	0.28
17_K	23_N	0.550	0.28
173_L	204_F	0.550	0.28
58_L	86_I	0.550	0.28
34_K	57_L	0.550	0.28
194_T	425_Q	0.549	0.28
38_R	43_L	0.549	0.28
173_L	266_L	0.549	0.28
284_V	310_L	0.549	0.28
242_S	245_D	0.549	0.28
122_G	130_V	0.548	0.28
347_E	350_E	0.548	0.28
142_V	378_N	0.548	0.28
185_A	443_P	0.548	0.28
137_G	171_V	0.547	0.28
366_N	372_K	0.546	0.28
287_Q	422_C	0.546	0.28
183_I	390_S	0.546	0.28
37_T	48_H	0.545	0.28
175_H	422_C	0.545	0.28
20_D	408_R	0.545	0.28
85_W	89_S	0.544	0.28
38_R	477_T	0.544	0.28
126_A	159_D	0.544	0.28
63_N	66_I	0.543	0.28
138_I	227_T	0.543	0.28
386_S	517_F	0.543	0.28
23_N	461_A	0.543	0.28
293_A	297_V	0.543	0.28
41_D	44_E	0.543	0.28
144_C	308_D	0.543	0.28
43_L	82_R	0.542	0.28
333_T	345_L	0.542	0.28
252_Q	256_E	0.540	0.28
23_N	91_V	0.540	0.28
29_N	62_A	0.540	0.28
190_V	415_T	0.540	0.28
66_I	114_P	0.539	0.28
15_Y	37_T	0.539	0.28
15_Y	57_L	0.539	0.28
376_L	470_I	0.539	0.28
234_P	265_H	0.538	0.28
255_V	422_C	0.538	0.28
422_C	431_I	0.538	0.28
132_T	386_S	0.538	0.28
452_I	505_S	0.537	0.27
413_A	423_G	0.537	0.27
58_L	82_R	0.536	0.27
206_G	210_V	0.536	0.27
23_N	30_D	0.535	0.27
122_G	196_H	0.534	0.27
435_V	472_A	0.534	0.27
169_G	446_L	0.534	0.27
431_I	437_T	0.533	0.27
101_T	350_E	0.532	0.27
200_L	232_A	0.532	0.27
215_C	308_D	0.531	0.27
414_A	517_F	0.531	0.27
322_V	325_V	0.530	0.27
64_G	110_E	0.529	0.27
114_P	118_Y	0.529	0.27
146_A	172_G	0.528	0.27
165_P	266_L	0.528	0.27
46_I	57_L	0.528	0.27
182_A	356_L	0.528	0.27
488_K	504_F	0.527	0.27
337_V	393_S	0.527	0.27
219_Q	241_V	0.526	0.27
363_R	415_T	0.526	0.27
42_G	78_R	0.526	0.27
112_L	117_G	0.526	0.27
326_R	365_A	0.525	0.27
323_T	356_L	0.525	0.27
234_P	272_R	0.525	0.27
348_E	414_A	0.525	0.27
78_R	184_N	0.525	0.27
449_V	463_R	0.525	0.27
189_V	226_G	0.524	0.27
231_Q	256_E	0.524	0.27
288_C	321_E	0.524	0.27
157_E	170_V	0.523	0.26
142_V	215_C	0.522	0.26
136_L	172_G	0.522	0.26
78_R	343_K	0.522	0.26
104_L	334_P	0.522	0.26
177_Y	181_V	0.521	0.26
163_K	263_E	0.521	0.26
196_H	226_G	0.521	0.26
345_L	384_L	0.520	0.26
284_V	287_Q	0.519	0.26
279_A	310_L	0.519	0.26
70_G	378_N	0.518	0.26
23_N	64_G	0.518	0.26
500_K	507_Q	0.518	0.26
177_Y	421_V	0.518	0.26
39_F	43_L	0.516	0.26
503_T	507_Q	0.514	0.26
390_S	519_P	0.513	0.26
217_K	518_N	0.513	0.26
302_A	482_I	0.511	0.26
434_Q	446_L	0.511	0.26
147_G	420_F	0.510	0.26
33_L	61_P	0.510	0.26
58_L	108_V	0.510	0.26
377_A	387_I	0.510	0.26
293_A	423_G	0.510	0.26
426_Q	472_A	0.509	0.26
101_T	342_G	0.509	0.26
35_A	234_P	0.509	0.26
322_V	517_F	0.509	0.26
373_K	429_S	0.509	0.26
52_G	368_S	0.508	0.25
20_D	45_L	0.507	0.25
399_L	403_Q	0.507	0.25
456_T	493_I	0.506	0.25
407_K	494_L	0.506	0.25
177_Y	217_K	0.506	0.25
212_G	331_L	0.505	0.25
174_N	432_T	0.505	0.25
66_I	221_E	0.505	0.25
224_L	262_A	0.505	0.25
390_S	422_C	0.504	0.25
245_D	463_R	0.504	0.25
131_G	192_I	0.504	0.25
153_V	172_G	0.504	0.25
137_G	198_I	0.503	0.25
100_H	334_P	0.502	0.25
140_T	446_L	0.502	0.25
120_F	494_L	0.501	0.25
380_V	464_W	0.501	0.25
352_Y	467_L	0.501	0.25
367_P	388_A	0.501	0.25
365_A	378_N	0.501	0.25
397_E	405_P	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3lazA	2	0.1778	100	0.856	Contact Map
3k3sA	2	0.1568	100	0.868	Contact Map
1vliA	2	0.1702	81.5	0.979	Contact Map
2wqpA	2	0.153	72.4	0.981	Contact Map
1msiA	1	0.1128	66.4	0.982	Contact Map
3g8rA	2	0.1568	62	0.982	Contact Map
1c89A	1	0.1702	56.2	0.983	Contact Map
4ur6A	2	0.1185	55.9	0.983	Contact Map
3teeA	1	0.2677	53	0.983	Contact Map
1ucsA	1	0.1185	52.4	0.983	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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