TTDT - ECOLI - GREMLIN Contacts

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TTDT - L-tartrate/succinate antiporter

UniProt:	P39414	Sequences: MKPSTEWWRYLAPLAVIAIIALLPVPAGLENHTWLYFAVFTGVIVGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSVIWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSARGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLLIGLMKSASHATLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETELQAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSNKAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTMVMVALIVVFYLLRYFFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYGSGYLPTADYWRLGAIFGLIFLVLLVITGLLWMPVVLL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12393
Length:	487 (412)
Sequences:	8858 (6015)
Seq/√Len:	296.3

ECOLI - TTDT CITT YBHI YFBS ARSB YFJV YBIR
BACSU - YFLS YWRK YDFA
HALSA - Q9HMC9
SULSO - Q980X8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
90_S	93_W	4.864	1.00
136_R	139_F	4.575	1.00
361_S	365_K	4.405	1.00
118_K	330_D	4.339	1.00
296_A	316_V	3.602	1.00
93_W	356_N	3.216	1.00
128_I	132_K	3.211	1.00
457_A	461_R	2.947	1.00
209_L	219_I	2.906	1.00
43_V	61_G	2.834	1.00
128_I	131_K	2.823	1.00
148_E	166_I	2.773	1.00
231_S	234_D	2.765	1.00
455_P	458_D	2.742	1.00
327_S	330_D	2.728	1.00
298_V	302_F	2.639	1.00
275_E	278_A	2.536	1.00
287_K	291_G	2.535	1.00
107_F	341_F	2.533	1.00
37_F	359_F	2.521	1.00
138_L	255_Y	2.515	1.00
191_S	458_D	2.473	1.00
329_D	334_N	2.464	1.00
115_G	320_M	2.395	1.00
34_W	38_A	2.390	1.00
302_F	306_Y	2.362	1.00
375_S	378_M	2.349	1.00
194_M	448_Y	2.345	1.00
295_G	299_L	2.338	1.00
292_L	316_V	2.313	1.00
45_V	49_L	2.291	1.00
458_D	461_R	2.283	1.00
111_M	317_V	2.243	1.00
290_L	294_V	2.218	1.00
362_W	366_L	2.191	1.00
149_L	243_S	2.191	1.00
292_L	319_L	2.181	1.00
284_S	288_R	2.165	1.00
237_L	241_P	2.130	1.00
39_V	64_I	2.116	1.00
352_T	356_N	2.042	1.00
195_W	199_V	2.019	1.00
42_G	46_G	1.955	1.00
386_V	471_L	1.941	1.00
115_G	289_M	1.936	1.00
112_F	296_A	1.892	1.00
302_F	305_D	1.883	1.00
233_G	237_L	1.883	1.00
256_V	259_P	1.882	1.00
366_L	370_S	1.876	1.00
388_Y	404_L	1.853	1.00
291_G	295_G	1.849	1.00
389_L	467_G	1.841	1.00
144_V	170_I	1.831	1.00
236_F	240_L	1.818	1.00
468_L	472_V	1.813	1.00
170_I	197_G	1.800	1.00
124_R	128_I	1.798	1.00
62_I	95_V	1.792	1.00
303_G	306_Y	1.768	1.00
252_W	256_V	1.760	1.00
476_I	480_L	1.758	1.00
382_A	475_V	1.746	1.00
282_L	286_E	1.745	1.00
203_V	246_L	1.739	1.00
46_G	49_L	1.711	1.00
108_A	317_V	1.706	1.00
207_I	243_S	1.694	1.00
252_W	255_Y	1.694	1.00
234_D	237_L	1.672	1.00
150_I	154_V	1.666	1.00
33_T	359_F	1.657	1.00
108_A	313_G	1.653	1.00
124_R	286_E	1.653	1.00
39_V	61_G	1.634	1.00
142_Y	251_P	1.630	1.00
114_T	117_E	1.622	1.00
46_G	57_V	1.614	1.00
93_W	96_S	1.613	1.00
292_L	320_M	1.601	1.00
145_M	200_A	1.583	1.00
249_L	469_I	1.573	1.00
64_I	68_L	1.570	1.00
98_F	345_A	1.557	1.00
39_V	65_I	1.549	1.00
148_E	201_D	1.525	1.00
385_V	430_A	1.523	1.00
426_M	478_G	1.519	1.00
282_L	285_R	1.515	1.00
274_T	278_A	1.503	1.00
39_V	68_L	1.502	1.00
35_L	68_L	1.500	1.00
477_T	481_W	1.493	1.00
244_I	248_L	1.478	1.00
65_I	353_G	1.474	1.00
107_F	111_M	1.472	1.00
63_S	318_A	1.462	1.00
276_L	280_G	1.458	1.00
246_L	470_F	1.447	1.00
200_A	204_T	1.445	1.00
299_L	306_Y	1.426	1.00
295_G	319_L	1.424	1.00
52_V	56_V	1.415	1.00
210_T	232_W	1.399	1.00
374_Y	378_M	1.398	1.00
43_V	57_V	1.389	1.00
103_I	341_F	1.389	1.00
253_L	256_V	1.388	1.00
133_M	143_A	1.384	1.00
365_K	369_G	1.381	1.00
460_W	464_A	1.372	1.00
354_L	360_I	1.366	1.00
36_Y	353_G	1.360	1.00
401_T	431_I	1.359	1.00
392_Y	397_A	1.343	1.00
52_V	57_V	1.335	1.00
294_V	298_V	1.326	1.00
35_L	70_P	1.325	1.00
277_Q	280_G	1.324	1.00
474_L	478_G	1.321	1.00
281_P	284_S	1.319	1.00
439_P	449_Y	1.317	1.00
355_N	361_S	1.310	1.00
33_T	362_W	1.303	1.00
135_H	139_F	1.299	1.00
152_A	204_T	1.294	1.00
366_L	369_G	1.290	1.00
55_A	339_N	1.288	1.00
198_I	448_Y	1.286	1.00
276_L	282_L	1.276	1.00
37_F	41_T	1.275	1.00
464_A	468_L	1.272	1.00
253_L	257_L	1.270	1.00
167_Y	447_I	1.251	1.00
269_P	273_E	1.237	1.00
240_L	244_I	1.235	1.00
241_P	477_T	1.234	1.00
390_L	394_F	1.233	1.00
38_A	42_G	1.225	1.00
437_L	467_G	1.215	1.00
299_L	312_V	1.210	1.00
270_R	274_T	1.209	1.00
288_R	291_G	1.209	1.00
476_I	479_L	1.208	1.00
131_K	273_E	1.208	1.00
204_T	247_V	1.208	1.00
207_I	240_L	1.189	1.00
134_G	139_F	1.189	1.00
40_F	354_L	1.184	1.00
144_V	173_L	1.179	1.00
354_L	359_F	1.179	1.00
292_L	299_L	1.177	1.00
457_A	460_W	1.177	1.00
114_T	336_A	1.175	1.00
253_L	469_I	1.173	1.00
393_F	467_G	1.167	1.00
408_M	427_V	1.161	1.00
117_E	335_K	1.151	1.00
471_L	475_V	1.148	1.00
145_M	196_M	1.148	1.00
265_G	268_V	1.146	1.00
371_L	383_L	1.133	1.00
417_E	423_F	1.132	1.00
283_C	286_E	1.124	1.00
362_W	365_K	1.122	1.00
234_D	420_L	1.116	1.00
36_Y	65_I	1.105	1.00
426_M	430_A	1.102	1.00
62_I	346_S	1.100	1.00
352_T	355_N	1.099	1.00
245_L	473_L	1.093	1.00
280_G	283_C	1.092	1.00
58_A	346_S	1.091	1.00
42_G	64_I	1.082	1.00
137_T	192_Y	1.082	1.00
289_M	292_L	1.081	1.00
149_L	247_V	1.074	1.00
157_S	160_A	1.073	1.00
288_R	323_L	1.071	1.00
108_A	314_Y	1.070	1.00
123_R	127_L	1.070	1.00
300_W	303_G	1.070	1.00
145_M	250_V	1.065	1.00
194_M	454_L	1.058	1.00
222_M	424_C	1.052	1.00
114_T	335_K	1.048	1.00
405_A	424_C	1.046	1.00
299_L	303_G	1.044	1.00
292_L	300_W	1.042	1.00
66_A	94_A	1.042	1.00
278_A	282_L	1.034	1.00
39_V	43_V	1.031	1.00
124_R	127_L	1.025	1.00
274_T	277_Q	1.024	1.00
153_P	207_I	1.017	1.00
285_R	288_R	1.016	1.00
276_L	279_M	1.014	1.00
96_S	352_T	1.012	1.00
249_L	473_L	1.011	1.00
409_I	413_L	1.010	1.00
288_R	292_L	1.009	1.00
386_V	390_L	1.005	1.00
450_G	453_Y	1.000	1.00
195_W	462_L	1.000	1.00
396_S	399_A	0.999	1.00
377_T	479_L	0.998	1.00
344_L	398_T	0.985	1.00
272_A	276_L	0.983	1.00
59_M	342_F	0.983	1.00
168_P	172_N	0.979	1.00
60_V	318_A	0.974	1.00
145_M	247_V	0.973	1.00
376_P	379_V	0.970	1.00
267_Q	270_R	0.967	1.00
254_A	258_Y	0.966	1.00
287_K	290_L	0.966	1.00
43_V	47_L	0.966	1.00
289_M	293_M	0.965	1.00
282_L	287_K	0.959	1.00
273_E	276_L	0.958	1.00
97_G	349_T	0.953	1.00
416_P	419_P	0.950	1.00
53_P	57_V	0.948	1.00
174_P	193_I	0.940	1.00
327_S	331_I	0.939	1.00
204_T	211_A	0.938	1.00
284_S	287_K	0.936	1.00
94_A	349_T	0.934	1.00
373_G	376_P	0.933	1.00
384_I	427_V	0.927	1.00
47_L	58_A	0.924	1.00
383_L	387_F	0.922	1.00
393_F	437_L	0.922	1.00
213_A	398_T	0.919	1.00
91_L	94_A	0.918	1.00
41_T	45_V	0.912	1.00
158_N	205_S	0.911	1.00
157_S	398_T	0.903	1.00
116_Y	121_L	0.899	1.00
162_G	201_D	0.896	1.00
62_I	66_A	0.896	1.00
172_N	176_L	0.891	1.00
141_G	193_I	0.890	1.00
280_G	284_S	0.887	1.00
101_S	310_A	0.885	1.00
270_R	273_E	0.884	1.00
281_P	285_R	0.883	1.00
278_A	281_P	0.882	1.00
369_G	372_S	0.880	1.00
337_A	340_V	0.880	1.00
248_L	252_W	0.879	1.00
138_L	251_P	0.876	1.00
250_V	254_A	0.873	1.00
274_T	280_G	0.871	1.00
296_A	299_L	0.871	1.00
472_V	476_I	0.870	1.00
393_F	441_A	0.868	1.00
437_L	464_A	0.866	1.00
413_L	419_P	0.864	1.00
205_S	212_M	0.862	1.00
308_D	311_M	0.861	1.00
385_V	471_L	0.860	1.00
365_K	368_A	0.852	1.00
393_F	434_G	0.848	1.00
203_V	250_V	0.847	1.00
90_S	94_A	0.847	1.00
437_L	460_W	0.847	1.00
281_P	287_K	0.845	1.00
214_P	432_G	0.844	1.00
239_M	429_A	0.843	1.00
292_L	303_G	0.843	1.00
277_Q	282_L	0.842	1.00
106_I	398_T	0.840	1.00
101_S	308_D	0.839	1.00
272_A	275_E	0.839	1.00
438_T	441_A	0.836	1.00
205_S	208_F	0.835	1.00
279_M	282_L	0.835	1.00
315_S	318_A	0.835	1.00
391_R	400_Y	0.833	1.00
410_A	413_L	0.833	1.00
151_L	161_R	0.832	1.00
439_P	446_P	0.831	1.00
242_L	473_L	0.830	1.00
58_A	62_I	0.829	1.00
147_S	166_I	0.829	1.00
396_S	434_G	0.829	1.00
258_Y	462_L	0.828	1.00
218_L	428_G	0.826	1.00
463_G	466_F	0.824	1.00
299_L	315_S	0.824	1.00
217_L	405_A	0.822	1.00
232_W	236_F	0.822	1.00
410_A	414_A	0.821	1.00
288_R	325_I	0.820	1.00
299_L	302_F	0.816	1.00
418_I	421_P	0.816	1.00
123_R	275_E	0.814	1.00
280_G	286_E	0.813	1.00
392_Y	441_A	0.812	1.00
43_V	350_L	0.812	1.00
92_S	96_S	0.811	1.00
163_A	447_I	0.811	1.00
293_M	300_W	0.809	1.00
54_G	57_V	0.808	1.00
275_E	280_G	0.804	1.00
398_T	401_T	0.801	1.00
397_A	434_G	0.800	1.00
288_R	300_W	0.799	1.00
65_I	350_L	0.793	0.99
429_A	474_L	0.791	0.99
296_A	300_W	0.785	0.99
467_G	470_F	0.780	0.99
300_W	313_G	0.780	0.99
275_E	279_M	0.776	0.99
381_V	426_M	0.776	0.99
70_P	353_G	0.775	0.99
206_A	433_L	0.775	0.99
397_A	441_A	0.773	0.99
206_A	243_S	0.772	0.99
235_W	425_L	0.772	0.99
55_A	62_I	0.772	0.99
434_G	441_A	0.768	0.99
458_D	462_L	0.768	0.99
289_M	300_W	0.768	0.99
212_M	215_N	0.766	0.99
194_M	197_G	0.765	0.99
208_F	211_A	0.765	0.99
207_I	236_F	0.763	0.99
265_G	270_R	0.763	0.99
49_L	52_V	0.763	0.99
275_E	281_P	0.760	0.99
384_I	408_M	0.753	0.99
100_N	220_G	0.753	0.99
214_P	398_T	0.753	0.99
179_S	193_I	0.750	0.99
54_G	58_A	0.750	0.99
109_A	296_A	0.747	0.99
90_S	356_N	0.747	0.99
214_P	442_T	0.744	0.99
279_M	283_C	0.743	0.99
218_L	405_A	0.742	0.99
202_C	435_S	0.740	0.99
465_I	469_I	0.739	0.99
385_V	426_M	0.738	0.99
247_V	251_P	0.738	0.99
276_L	284_S	0.736	0.99
60_V	63_S	0.733	0.99
170_I	193_I	0.733	0.99
40_F	350_L	0.732	0.99
130_V	173_L	0.728	0.99
272_A	280_G	0.727	0.99
152_A	211_A	0.726	0.99
280_G	285_R	0.726	0.99
152_A	158_N	0.725	0.99
297_L	300_W	0.721	0.99
370_S	373_G	0.716	0.99
55_A	58_A	0.715	0.99
368_A	372_S	0.715	0.99
292_L	296_A	0.715	0.99
317_V	321_L	0.711	0.99
159_S	212_M	0.711	0.99
62_I	349_T	0.710	0.99
161_R	201_D	0.707	0.99
209_L	236_F	0.707	0.99
398_T	442_T	0.707	0.99
386_V	475_V	0.706	0.99
104_W	345_A	0.706	0.99
382_A	471_L	0.705	0.99
398_T	443_G	0.702	0.99
261_V	264_S	0.702	0.99
65_I	70_P	0.699	0.99
191_S	195_W	0.698	0.99
264_S	268_V	0.696	0.99
47_L	57_V	0.696	0.99
152_A	205_S	0.696	0.99
36_Y	357_T	0.695	0.99
124_R	280_G	0.695	0.99
249_L	253_L	0.691	0.99
105_L	313_G	0.689	0.99
212_M	432_G	0.689	0.99
56_V	60_V	0.689	0.99
158_N	211_A	0.689	0.99
107_F	336_A	0.686	0.98
379_V	423_F	0.686	0.98
307_I	312_V	0.686	0.98
273_E	281_P	0.684	0.98
340_V	398_T	0.683	0.98
442_T	445_S	0.683	0.98
196_M	200_A	0.683	0.98
71_W	349_T	0.683	0.98
60_V	64_I	0.683	0.98
279_M	284_S	0.682	0.98
324_R	327_S	0.682	0.98
276_L	281_P	0.681	0.98
46_G	60_V	0.681	0.98
198_I	444_P	0.680	0.98
94_A	97_G	0.678	0.98
250_V	466_F	0.677	0.98
364_G	368_A	0.677	0.98
268_V	272_A	0.674	0.98
371_L	374_Y	0.673	0.98
277_Q	285_R	0.673	0.98
348_I	402_S	0.673	0.98
406_P	409_I	0.672	0.98
54_G	396_S	0.671	0.98
59_M	346_S	0.671	0.98
62_I	65_I	0.670	0.98
94_A	98_F	0.669	0.98
396_S	400_Y	0.669	0.98
278_A	284_S	0.666	0.98
392_Y	434_G	0.665	0.98
103_I	345_A	0.665	0.98
44_I	47_L	0.665	0.98
301_I	305_D	0.664	0.98
61_G	65_I	0.663	0.98
390_L	467_G	0.663	0.98
115_G	325_I	0.662	0.98
300_W	304_G	0.661	0.98
214_P	401_T	0.661	0.98
409_I	412_A	0.659	0.98
36_Y	70_P	0.657	0.98
240_L	243_S	0.656	0.98
146_F	150_I	0.656	0.98
236_F	241_P	0.654	0.98
392_Y	396_S	0.654	0.98
262_L	265_G	0.653	0.98
171_R	175_P	0.653	0.98
245_L	477_T	0.652	0.98
286_E	299_L	0.651	0.98
45_V	51_P	0.650	0.98
251_P	255_Y	0.649	0.98
215_N	432_G	0.648	0.98
114_T	118_K	0.648	0.98
281_P	286_E	0.645	0.98
46_G	51_P	0.645	0.98
269_P	272_A	0.643	0.98
50_E	449_Y	0.642	0.98
221_L	405_A	0.640	0.98
309_A	313_G	0.635	0.98
325_I	328_W	0.635	0.98
249_L	252_W	0.634	0.97
167_Y	194_M	0.634	0.97
342_F	346_S	0.633	0.97
218_L	401_T	0.631	0.97
242_L	246_L	0.629	0.97
35_L	39_V	0.628	0.97
388_Y	431_I	0.626	0.97
214_P	344_L	0.626	0.97
128_I	276_L	0.624	0.97
222_M	229_T	0.623	0.97
326_I	331_I	0.623	0.97
215_N	235_W	0.622	0.97
309_A	312_V	0.622	0.97
103_I	344_L	0.622	0.97
162_G	448_Y	0.620	0.97
97_G	352_T	0.617	0.97
106_I	110_F	0.616	0.97
66_A	311_M	0.616	0.97
42_G	49_L	0.615	0.97
207_I	211_A	0.613	0.97
217_L	402_S	0.612	0.97
112_F	320_M	0.611	0.97
271_W	275_E	0.611	0.97
219_I	229_T	0.610	0.97
119_T	289_M	0.610	0.97
204_T	208_F	0.609	0.97
238_G	477_T	0.609	0.97
50_E	54_G	0.607	0.97
91_L	95_V	0.605	0.97
96_S	99_S	0.604	0.97
69_S	94_A	0.604	0.97
387_F	391_R	0.603	0.97
209_L	216_L	0.601	0.97
96_S	100_N	0.600	0.97
345_A	349_T	0.599	0.96
429_A	433_L	0.599	0.96
44_I	394_F	0.597	0.96
241_P	245_L	0.597	0.96
382_A	386_V	0.596	0.96
388_Y	427_V	0.591	0.96
241_P	244_I	0.590	0.96
131_K	276_L	0.590	0.96
465_I	468_L	0.590	0.96
389_L	471_L	0.590	0.96
112_F	316_V	0.589	0.96
48_I	51_P	0.588	0.96
148_E	161_R	0.588	0.96
330_D	334_N	0.588	0.96
433_L	470_F	0.586	0.96
106_I	344_L	0.585	0.96
297_L	301_I	0.584	0.96
413_L	416_P	0.584	0.96
50_E	53_P	0.583	0.96
198_I	202_C	0.583	0.96
286_E	290_L	0.582	0.96
202_C	444_P	0.582	0.96
158_N	210_T	0.580	0.96
159_S	205_S	0.580	0.96
242_L	477_T	0.579	0.96
286_E	297_L	0.579	0.96
158_N	201_D	0.577	0.96
161_R	166_I	0.576	0.96
367_L	387_F	0.574	0.96
289_M	296_A	0.574	0.96
162_G	444_P	0.574	0.96
440_Y	456_T	0.573	0.95
263_K	267_Q	0.571	0.95
105_L	157_S	0.570	0.95
330_D	335_K	0.570	0.95
268_V	273_E	0.569	0.95
203_V	247_V	0.568	0.95
38_A	41_T	0.567	0.95
263_K	266_D	0.566	0.95
180_Q	191_S	0.565	0.95
434_G	442_T	0.565	0.95
297_L	303_G	0.564	0.95
118_K	326_I	0.564	0.95
218_L	424_C	0.564	0.95
301_I	306_Y	0.563	0.95
199_V	250_V	0.563	0.95
464_A	467_G	0.562	0.95
157_S	161_R	0.562	0.95
158_N	212_M	0.561	0.95
196_M	254_A	0.561	0.95
44_I	395_A	0.559	0.95
123_R	176_L	0.558	0.95
228_A	234_D	0.558	0.95
375_S	383_L	0.557	0.95
167_Y	451_S	0.557	0.95
315_S	319_L	0.557	0.95
284_S	291_G	0.557	0.95
66_A	69_S	0.556	0.95
145_M	251_P	0.555	0.95
63_S	314_Y	0.552	0.94
102_V	106_I	0.552	0.94
388_Y	400_Y	0.551	0.94
385_V	474_L	0.550	0.94
159_S	396_S	0.548	0.94
46_G	52_V	0.548	0.94
328_W	331_I	0.547	0.94
198_I	445_S	0.546	0.94
370_S	374_Y	0.546	0.94
288_R	302_F	0.545	0.94
238_G	482_M	0.544	0.94
417_E	421_P	0.541	0.94
141_G	192_Y	0.541	0.94
289_M	299_L	0.540	0.94
462_L	465_I	0.538	0.94
47_L	347_L	0.538	0.94
114_T	334_N	0.538	0.94
254_A	462_L	0.538	0.94
217_L	398_T	0.537	0.94
354_L	357_T	0.537	0.94
266_D	269_P	0.537	0.94
288_R	303_G	0.535	0.94
212_M	442_T	0.534	0.93
148_E	200_A	0.534	0.93
425_L	429_A	0.534	0.93
95_V	99_S	0.533	0.93
222_M	228_A	0.533	0.93
428_G	432_G	0.532	0.93
235_W	428_G	0.530	0.93
141_G	251_P	0.530	0.93
377_T	476_I	0.530	0.93
293_M	299_L	0.529	0.93
354_L	403_A	0.528	0.93
272_A	277_Q	0.527	0.93
475_V	479_L	0.527	0.93
219_I	230_L	0.525	0.93
143_A	220_G	0.524	0.93
351_A	449_Y	0.524	0.93
32_H	35_L	0.523	0.93
211_A	214_P	0.523	0.93
152_A	161_R	0.522	0.93
191_S	258_Y	0.522	0.93
289_M	298_V	0.522	0.93
232_W	235_W	0.521	0.93
71_W	94_A	0.521	0.93
160_A	235_W	0.520	0.93
466_F	469_I	0.520	0.93
138_L	142_Y	0.519	0.92
142_Y	146_F	0.519	0.92
148_E	197_G	0.518	0.92
117_E	122_G	0.516	0.92
293_M	297_L	0.516	0.92
397_A	400_Y	0.516	0.92
274_T	284_S	0.515	0.92
467_G	471_L	0.515	0.92
397_A	442_T	0.515	0.92
275_E	284_S	0.514	0.92
471_L	474_L	0.513	0.92
105_L	109_A	0.512	0.92
326_I	329_D	0.512	0.92
71_W	90_S	0.512	0.92
446_P	449_Y	0.512	0.92
144_V	148_E	0.511	0.92
287_K	298_V	0.511	0.92
43_V	46_G	0.510	0.92
277_Q	283_C	0.510	0.92
241_P	481_W	0.509	0.92
254_A	257_L	0.508	0.92
246_L	433_L	0.508	0.92
412_A	415_M	0.507	0.92
245_L	469_I	0.507	0.92
358_G	361_S	0.506	0.92
274_T	279_M	0.506	0.92
388_Y	430_A	0.505	0.91
91_L	311_M	0.505	0.91
36_Y	354_L	0.504	0.91
158_N	214_P	0.503	0.91
112_F	317_V	0.503	0.91
401_T	427_V	0.502	0.91
94_A	99_S	0.501	0.91
152_A	155_T	0.501	0.91
303_G	308_D	0.500	0.91
442_T	446_P	0.500	0.91
116_Y	155_T	0.500	0.91

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4f35D	2	0.8789	100	0.389	Contact Map
4r1iA	2	0.9097	100	0.662	Contact Map
4r0cA	3	0.8563	99.9	0.729	Contact Map
2m20A	2	0.1232	21	0.966	Contact Map
2ksfA	1	0.2197	15.8	0.968	Contact Map
4pd6A	3	0.7721	11.7	0.97	Contact Map
1ldfA	3	0.4517	8.6	0.972	Contact Map
3tdsE	3	0.4682	7.7	0.972	Contact Map
2rddB	1	0.0739	6.2	0.973	Contact Map
3l1lA	2	0.4066	5.9	0.974	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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