GREMLIN Database
YJJW - Uncharacterized protein YjjW
UniProt: P39409 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12599
Length: 287 (268)
Sequences: 1041 (861)
Seq/√Len: 52.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
180_S190_D4.8121.00
118_V130_V4.7911.00
8_V28_L3.7921.00
9_S43_T3.7171.00
116_I137_I3.1811.00
212_L240_V3.0711.00
107_R144_R3.0111.00
154_G173_L2.8951.00
136_A139_N2.8931.00
158_E200_L2.8041.00
173_L198_I2.6711.00
134_F148_C2.6411.00
106_V137_I2.6081.00
76_C82_C2.6071.00
147_T170_G2.5961.00
135_T167_V2.4841.00
131_V163_K2.4281.00
180_S192_Q2.4251.00
6_A129_F2.3861.00
12_I15_S2.3681.00
79_C82_C2.3211.00
76_C79_C2.3121.00
99_V136_A2.2891.00
6_A126_Q2.2581.00
138_K169_D2.2351.00
162_E200_L2.1331.00
105_H108_K2.1241.00
186_L218_Q2.1111.00
182_C185_Q2.0931.00
97_M102_V2.0681.00
210_L232_I2.0311.00
39_H151_D2.0021.00
103_L137_I1.9561.00
102_V133_L1.9260.99
57_C79_C1.9170.99
178_W231_F1.9020.99
183_H191_N1.8960.99
171_A201_L1.8830.99
26_L106_V1.8740.99
33_L194_I1.8420.99
158_E196_R1.8320.99
224_H228_L1.7770.99
7_L96_S1.7730.99
184_Q190_D1.7720.99
168_C171_A1.7690.99
100_D136_A1.7220.99
136_A144_R1.6910.99
158_E162_E1.6830.99
62_L69_V1.6550.98
6_A28_L1.6540.98
222_L226_E1.6540.98
151_D209_E1.6260.98
48_N88_Q1.5820.98
59_H77_E1.5750.98
124_T156_L1.5640.98
57_C82_C1.5540.98
102_V106_V1.5530.98
32_N153_N1.5480.98
177_A218_Q1.5170.97
110_V114_E1.5080.97
118_V133_L1.4440.96
71_W91_T1.4430.96
199_Y234_G1.4230.96
195_K231_F1.4190.96
268_L273_K1.4150.96
57_C76_C1.3940.95
25_A151_D1.3870.95
81_T84_K1.3810.95
118_V123_A1.3750.95
137_I148_C1.3690.95
212_L228_L1.3640.95
22_S113_I1.3570.95
183_H189_R1.3480.95
219_V224_H1.3440.94
25_A119_S1.3430.94
268_L272_L1.3260.94
124_T153_N1.3260.94
222_L275_R1.3090.94
131_V135_T1.3080.94
28_L123_A1.2890.93
124_T164_L1.2780.93
199_Y231_F1.2740.93
124_T161_W1.2620.92
171_A206_K1.2600.92
155_M189_R1.2560.92
199_Y203_E1.2560.92
178_W224_H1.2420.92
107_R110_V1.2280.91
214_V242_L1.2110.91
253_E260_A1.1890.90
223_Q227_E1.1840.90
219_V246_H1.1710.89
171_A198_I1.1610.89
72_N75_V1.1560.89
175_L198_I1.1540.89
202_A235_L1.1470.88
209_E241_R1.1420.88
221_Y224_H1.1420.88
150_V171_A1.1110.87
36_K186_L1.1090.86
36_K185_Q1.1060.86
189_R194_I1.1030.86
61_A79_C1.1020.86
131_V164_L1.0920.86
154_G198_I1.0860.85
20_P170_G1.0860.85
196_R199_Y1.0690.84
118_V148_C1.0680.84
155_M193_Q1.0650.84
50_C53_C1.0590.84
24_L109_A1.0580.84
123_A130_V1.0560.84
118_V134_F1.0540.83
138_K167_V1.0500.83
103_L144_R1.0480.83
13_P108_K1.0470.83
172_M244_A1.0460.83
44_M258_A1.0460.83
196_R200_L1.0420.83
272_L276_G1.0360.82
226_E230_A1.0320.82
159_T162_E1.0260.82
40_N252_G1.0230.82
192_Q196_R1.0200.81
130_V134_F0.9950.80
134_F168_C0.9940.80
216_P265_V0.9940.80
32_N155_M0.9900.79
58_P81_T0.9860.79
109_A113_I0.9840.79
182_C221_Y0.9810.79
273_K276_G0.9800.79
155_M190_D0.9660.78
99_V129_F0.9640.78
246_H249_G0.9640.78
10_K29_Q0.9630.78
175_L195_K0.9610.77
152_S171_A0.9590.77
32_N125_T0.9560.77
51_G54_V0.9560.77
95_Q101_E0.9560.77
138_K148_C0.9540.77
127_L160_G0.9490.76
80_D83_L0.9480.76
178_W227_E0.9470.76
10_K95_Q0.9320.75
36_K261_T0.9300.75
28_L118_V0.9280.75
122_E153_N0.9270.75
130_V150_V0.9160.74
249_G260_A0.9140.74
52_E87_P0.9130.74
65_V68_K0.9120.74
39_H44_M0.9050.73
177_A186_L0.9000.73
202_A236_G0.8990.72
152_S173_L0.8950.72
171_A208_A0.8880.72
44_M253_E0.8860.71
151_D172_M0.8850.71
214_V273_K0.8820.71
124_T150_V0.8820.71
182_C223_Q0.8770.71
151_D241_R0.8770.71
128_P163_K0.8750.70
151_D248_H0.8710.70
162_E204_R0.8650.70
103_L136_A0.8610.69
149_L170_G0.8570.69
98_S101_E0.8550.69
157_S193_Q0.8510.68
69_V73_A0.8510.68
61_A75_V0.8500.68
25_A39_H0.8480.68
61_A82_C0.8480.68
13_P29_Q0.8480.68
191_N195_K0.8390.67
198_I210_L0.8360.67
272_L275_R0.8290.66
9_S29_Q0.8280.66
259_S263_E0.8260.66
60_Q65_V0.8220.66
232_I240_V0.8210.65
29_Q94_A0.8200.65
253_E256_S0.8190.65
172_M241_R0.8180.65
180_S184_Q0.8110.65
101_E124_T0.8100.64
181_E185_Q0.8080.64
110_V144_R0.8040.64
196_R203_E0.8010.64
202_A208_A0.7990.63
212_L232_I0.7980.63
156_L161_W0.7860.62
131_V167_V0.7800.62
123_A150_V0.7800.62
100_D104_S0.7740.61
183_H194_I0.7710.61
12_I25_A0.7690.60
220_D276_G0.7680.60
274_V277_V0.7660.60
102_V129_F0.7660.60
222_L272_L0.7650.60
168_C198_I0.7630.60
177_A224_H0.7630.60
124_T130_V0.7600.59
22_S29_Q0.7570.59
68_K150_V0.7550.59
200_L204_R0.7530.59
153_N156_L0.7510.59
198_I201_L0.7490.58
39_H249_G0.7480.58
68_K73_A0.7450.58
28_L130_V0.7440.58
54_V60_Q0.7420.58
251_Y255_Q0.7420.58
154_G161_W0.7410.58
77_E81_T0.7410.58
207_L239_P0.7400.57
232_I237_D0.7380.57
182_C218_Q0.7380.57
62_L67_G0.7350.57
99_V133_L0.7340.57
185_Q218_Q0.7340.57
178_W195_K0.7320.57
240_V246_H0.7270.56
63_Q75_V0.7260.56
150_V156_L0.7260.56
11_I105_H0.7250.56
54_V62_L0.7210.55
172_M211_R0.7190.55
182_C224_H0.7160.55
217_G220_D0.7120.55
152_S246_H0.7100.54
125_T153_N0.7100.54
177_A219_V0.7080.54
214_V225_I0.7070.54
56_Q85_R0.7060.54
198_I235_L0.6960.53
269_A273_K0.6950.53
13_P109_A0.6950.53
26_L102_V0.6930.53
178_W228_L0.6910.52
216_P220_D0.6900.52
8_V97_M0.6890.52
37_N213_L0.6870.52
149_L172_M0.6850.52
99_V132_A0.6840.52
218_Q262_P0.6840.52
109_A252_G0.6830.52
15_S43_T0.6830.52
214_V220_D0.6790.51
22_S245_F0.6790.51
33_L153_N0.6780.51
69_V146_L0.6770.51
10_K13_P0.6770.51
39_H201_L0.6710.50
13_P123_A0.6680.50
200_L203_E0.6680.50
97_M101_E0.6610.49
39_H262_P0.6600.49
236_G239_P0.6580.49
107_R139_N0.6570.49
20_P147_T0.6520.48
47_C53_C0.6500.48
179_G187_T0.6480.48
47_C50_C0.6460.48
34_R55_P0.6450.48
184_Q229_A0.6450.48
212_L224_H0.6420.47
13_P113_I0.6420.47
10_K224_H0.6410.47
106_V116_I0.6400.47
92_P255_Q0.6400.47
175_L228_L0.6390.47
95_Q105_H0.6380.47
230_A272_L0.6360.47
12_I249_G0.6360.47
31_C35_C0.6320.46
107_R137_I0.6290.46
57_C154_G0.6280.46
116_I146_L0.6280.46
135_T166_P0.6260.46
179_G227_E0.6260.46
116_I133_L0.6250.45
245_F262_P0.6250.45
107_R146_L0.6240.45
16_C218_Q0.6220.45
60_Q188_G0.6190.45
52_E55_P0.6170.45
177_A182_C0.6160.44
66_D196_R0.6120.44
12_I16_C0.6110.44
74_V234_G0.6110.44
19_G23_R0.6050.43
90_A94_A0.6050.43
85_R232_I0.6050.43
52_E85_R0.6000.43
99_V106_V0.6000.43
148_C187_T0.5980.43
225_I228_L0.5970.43
197_S213_L0.5960.42
97_M106_V0.5950.42
172_M240_V0.5930.42
11_I26_L0.5930.42
98_S104_S0.5930.42
51_G77_E0.5900.42
165_L204_R0.5860.41
104_S230_A0.5850.41
76_C80_D0.5850.41
14_F144_R0.5840.41
208_A235_L0.5830.41
181_E223_Q0.5830.41
220_D272_L0.5820.41
165_L200_L0.5800.41
54_V64_I0.5790.41
61_A72_N0.5790.41
156_L190_D0.5780.41
219_V249_G0.5770.40
137_I145_H0.5750.40
168_C180_S0.5750.40
191_N194_I0.5750.40
68_K72_N0.5740.40
7_L126_Q0.5730.40
28_L102_V0.5730.40
213_L243_N0.5730.40
106_V133_L0.5730.40
34_R101_E0.5730.40
165_L206_K0.5720.40
69_V152_S0.5720.40
57_C61_A0.5700.40
264_D273_K0.5690.40
35_C38_C0.5680.40
123_A156_L0.5650.39
10_K153_N0.5620.39
134_F254_A0.5590.39
125_T132_A0.5580.39
264_D270_D0.5580.39
130_V137_I0.5570.38
135_T139_N0.5560.38
241_R255_Q0.5560.38
6_A99_V0.5520.38
124_T160_G0.5490.38
270_D273_K0.5490.38
64_I67_G0.5490.38
83_L91_T0.5480.38
59_H239_P0.5480.38
12_I40_N0.5460.37
9_S17_V0.5450.37
164_L167_V0.5420.37
72_N82_C0.5420.37
101_E133_L0.5420.37
164_L168_C0.5400.37
12_I24_L0.5400.37
116_I148_C0.5390.37
28_L97_M0.5370.37
66_D104_S0.5360.36
102_V137_I0.5360.36
215_I221_Y0.5340.36
137_I146_L0.5330.36
6_A9_S0.5320.36
46_R90_A0.5320.36
51_G64_I0.5310.36
16_C33_L0.5290.36
151_D255_Q0.5280.36
130_V148_C0.5280.36
253_E258_A0.5270.36
22_S33_L0.5260.35
162_E166_P0.5260.35
56_Q181_E0.5250.35
199_Y223_Q0.5240.35
218_Q245_F0.5230.35
242_L276_G0.5230.35
6_A191_N0.5230.35
157_S160_G0.5200.35
215_I219_V0.5200.35
131_V166_P0.5200.35
56_Q80_D0.5200.35
13_P154_G0.5200.35
151_D173_L0.5190.35
210_L231_F0.5190.35
154_G244_A0.5170.35
20_P276_G0.5170.35
146_L201_L0.5170.35
62_L71_W0.5140.34
55_P95_Q0.5130.34
18_D23_R0.5130.34
13_P22_S0.5110.34
20_P112_F0.5100.34
68_K103_L0.5090.34
233_K277_V0.5090.34
245_F252_G0.5090.34
78_Q123_A0.5080.34
243_N246_H0.5070.34
39_H248_H0.5060.34
74_V104_S0.5050.33
198_I208_A0.5050.33
210_L253_E0.5030.33
242_L265_V0.5020.33
121_G211_R0.5020.33
247_A250_V0.5010.33
66_D233_K0.5000.33
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3c8fA 1 0.8223 100 0.605 Contact Map
1hfeL 2 0.8467 100 0.71 Contact Map
3canA 2 0.5331 100 0.71 Contact Map
3rfaA 1 0.7666 100 0.752 Contact Map
2yx0A 1 0.7805 100 0.765 Contact Map
2z2uA 1 0.777 99.9 0.77 Contact Map
1q16B 2 0.7875 99.9 0.783 Contact Map
1oltA 1 0.8362 99.9 0.784 Contact Map
4njhA 2 0.6411 99.9 0.788 Contact Map
2vpzB 2 0.5854 99.9 0.791 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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