GREMLIN Database
YJJU - Uncharacterized protein YjjU
UniProt: P39407 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12597
Length: 357 (282)
Sequences: 4670 (3485)
Seq/√Len: 207.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
140_R179_I4.5381.00
48_R291_R3.8771.00
45_E295_R3.7701.00
45_E291_R3.7531.00
288_K292_L3.5731.00
64_A163_S3.5061.00
140_R147_N3.1611.00
38_F293_C3.0801.00
68_S160_I2.9991.00
297_F300_T2.9471.00
45_E294_G2.7471.00
67_L134_F2.6821.00
138_A149_F2.5281.00
142_D179_I2.4801.00
175_S180_N2.3151.00
284_R288_K2.2851.00
44_D291_R2.2471.00
45_E48_R2.2091.00
36_G62_A2.1861.00
49_A302_G2.1841.00
82_I86_T2.1671.00
175_S178_G2.1291.00
147_N181_Y2.1201.00
29_C39_T2.1121.00
60_T137_C2.0751.00
241_H245_S2.0201.00
291_R295_R1.9591.00
292_L296_Y1.8371.00
42_V206_I1.7691.00
48_R75_P1.7441.00
288_K291_R1.7421.00
182_L186_I1.7291.00
54_F204_V1.7161.00
79_R83_M1.7061.00
138_A181_Y1.6921.00
263_F301_V1.6891.00
112_A116_Q1.6801.00
268_P293_C1.6731.00
146_P187_S1.6451.00
26_A56_L1.6391.00
80_K84_R1.6281.00
234_P237_N1.6021.00
133_S150_L1.5881.00
114_A157_L1.5791.00
123_T126_R1.5751.00
138_A159_V1.5691.00
235_L238_L1.5681.00
120_Q123_T1.5681.00
298_L302_G1.5621.00
31_G189_A1.5231.00
48_R295_R1.5211.00
140_R143_D1.5101.00
190_I205_V1.5071.00
226_W229_D1.4981.00
26_A195_A1.4881.00
110_V158_D1.4741.00
127_L131_G1.4611.00
45_E49_A1.4591.00
160_I163_S1.4481.00
118_P122_D1.4471.00
294_G298_L1.4411.00
76_G79_R1.4371.00
127_L130_S1.4351.00
78_A81_V1.4281.00
165_A174_V1.4271.00
301_V304_L1.4121.00
34_Q278_S1.3871.00
88_K91_F1.3821.00
277_G282_A1.3721.00
280_I284_R1.3631.00
292_L295_R1.3611.00
194_E197_R1.3601.00
176_L181_Y1.3461.00
102_N172_S1.3441.00
137_C146_P1.3431.00
42_V294_G1.3411.00
146_P188_D1.3351.00
194_E198_Q1.3331.00
135_Y198_Q1.3301.00
265_I293_C1.3271.00
285_E289_L1.3231.00
45_E298_L1.3211.00
30_E190_I1.3201.00
253_I264_E1.3071.00
33_G166_I1.3031.00
29_C57_Y1.2911.00
149_F159_V1.2851.00
188_D193_K1.2831.00
57_Y67_L1.2821.00
57_Y71_I1.2801.00
65_Q113_T1.2771.00
249_I253_I1.2761.00
193_K197_R1.2741.00
110_V161_R1.2731.00
111_E115_S1.2701.00
211_S266_Y1.2581.00
64_A164_S1.2551.00
141_Q182_L1.2541.00
49_A295_R1.2321.00
252_F255_K1.2301.00
242_H245_S1.2191.00
242_H246_Y1.2111.00
47_M76_G1.2081.00
68_S134_F1.2051.00
251_Q255_K1.2031.00
81_V85_Y1.1981.00
242_H247_R1.1971.00
25_I202_T1.1891.00
46_F294_G1.1801.00
83_M86_T1.1791.00
28_V195_A1.1741.00
126_R129_D1.1611.00
243_E247_R1.1531.00
24_R55_D1.1511.00
173_G182_L1.1471.00
139_C187_S1.1461.00
237_N240_Q1.1431.00
268_P296_Y1.1371.00
58_L135_Y1.1301.00
27_L57_Y1.1301.00
158_D174_V1.1301.00
24_R201_K1.1271.00
235_L240_Q1.1261.00
141_Q173_G1.1241.00
230_S233_Q1.1241.00
297_F301_V1.1231.00
78_A85_Y1.1221.00
106_L161_R1.1211.00
246_Y250_Q1.1081.00
279_R282_A1.1051.00
101_G105_D1.1021.00
49_A298_L1.1011.00
118_P121_M1.0961.00
282_A285_E1.0931.00
225_R229_D1.0681.00
89_R92_F1.0641.00
195_A200_A1.0641.00
235_L239_V1.0631.00
71_I134_F1.0601.00
78_A86_T1.0571.00
236_V240_Q1.0551.00
135_Y194_E1.0531.00
29_C67_L1.0391.00
196_A203_L1.0361.00
89_R95_L1.0251.00
61_S183_D1.0061.00
250_Q253_I1.0061.00
53_P73_N0.9931.00
289_L292_L0.9871.00
238_L242_H0.9851.00
26_A200_A0.9731.00
58_L195_A0.9711.00
247_R250_Q0.9581.00
118_P123_T0.9581.00
79_R84_R0.9560.99
111_E114_A0.9510.99
231_S234_P0.9430.99
274_I277_G0.9420.99
202_T206_I0.9380.99
293_C296_Y0.9320.99
138_A147_N0.9290.99
245_S248_D0.9280.99
140_R181_Y0.9250.99
214_Y251_Q0.9240.99
78_A83_M0.9220.99
251_Q254_E0.9210.99
29_C206_I0.9160.99
252_F256_P0.9080.99
39_T208_T0.9080.99
27_L54_F0.9040.99
65_Q160_I0.9030.99
62_A166_I0.9010.99
76_G80_K0.8980.99
148_Y194_E0.8980.99
239_V243_E0.8950.99
79_R85_Y0.8950.99
62_A83_M0.8920.99
273_S286_D0.8850.99
83_M284_R0.8840.99
222_R226_W0.8820.99
121_M126_R0.8810.99
167_P186_I0.8760.99
137_C163_S0.8720.99
249_I252_F0.8700.99
264_E267_P0.8660.99
268_P289_L0.8640.99
88_K92_F0.8630.99
289_L293_C0.8620.99
56_L200_A0.8620.99
241_H244_T0.8610.99
142_D180_N0.8560.99
39_T43_L0.8510.99
255_K259_K0.8500.99
41_G290_G0.8400.99
107_D111_E0.8360.99
110_V114_A0.8350.99
291_R294_G0.8340.99
248_D252_F0.8330.99
78_A82_I0.8300.99
254_E258_G0.8270.99
295_R299_A0.8250.99
72_C117_M0.8230.98
246_Y253_I0.8220.98
40_A66_N0.8210.98
135_Y150_L0.8200.98
257_P267_P0.8190.98
56_L195_A0.8170.98
81_V84_R0.8170.98
149_F181_Y0.8140.98
137_C148_Y0.8080.98
162_A176_L0.8070.98
155_N158_D0.8070.98
44_D48_R0.8030.98
149_F176_L0.7990.98
218_Q221_K0.7950.98
207_R210_P0.7920.98
223_M228_G0.7920.98
185_G189_A0.7910.98
207_R264_E0.7910.98
87_T91_F0.7890.98
246_Y249_I0.7890.98
79_R86_T0.7810.98
273_S277_G0.7810.98
51_F302_G0.7800.98
145_A179_I0.7800.98
62_A287_Y0.7800.98
150_L198_Q0.7780.98
222_R228_G0.7730.98
47_M73_N0.7720.98
300_T303_K0.7720.98
243_E246_Y0.7710.98
265_I297_F0.7620.98
41_G45_E0.7580.97
47_M75_P0.7560.97
128_F153_K0.7550.97
239_V245_S0.7550.97
56_L135_Y0.7530.97
219_W222_R0.7530.97
230_S234_P0.7530.97
44_D80_K0.7520.97
237_N241_H0.7520.97
78_A84_R0.7480.97
29_C43_L0.7480.97
242_H250_Q0.7460.97
58_L194_E0.7430.97
71_I130_S0.7430.97
87_T92_F0.7410.97
138_A162_A0.7370.97
83_M287_Y0.7350.97
231_S235_L0.7350.97
285_E288_K0.7340.97
220_F223_M0.7340.97
93_D96_R0.7330.97
130_S156_W0.7280.97
34_Q87_T0.7280.97
77_Y80_K0.7270.97
248_D251_Q0.7200.97
227_L231_S0.7150.96
262_I267_P0.7140.96
59_G191_P0.7100.96
257_P260_L0.7090.96
263_F267_P0.7060.96
122_D128_F0.7060.96
223_M229_D0.7030.96
64_A160_I0.7010.96
41_G291_R0.7000.96
244_T247_R0.7000.96
28_V192_V0.6990.96
133_S198_Q0.6990.96
150_L153_K0.6980.96
258_G263_F0.6960.96
69_A117_M0.6960.96
166_I182_L0.6930.96
208_T211_S0.6900.96
298_L301_V0.6840.95
238_L245_S0.6820.95
54_F70_F0.6800.95
236_V239_V0.6800.95
99_R103_L0.6790.95
294_G297_F0.6790.95
67_L136_M0.6770.95
37_I286_D0.6770.95
192_V195_A0.6750.95
207_R211_S0.6740.95
39_T206_I0.6730.95
196_A256_P0.6720.95
39_T66_N0.6700.95
135_Y148_Y0.6690.95
88_K93_D0.6670.95
204_V301_V0.6660.95
257_P264_E0.6660.95
220_F224_E0.6650.95
201_K261_R0.6630.94
139_C189_A0.6630.94
60_T188_D0.6590.94
239_V246_Y0.6580.94
248_D255_K0.6580.94
27_L43_L0.6580.94
26_A203_L0.6570.94
29_C208_T0.6530.94
23_G201_K0.6520.94
203_L207_R0.6520.94
219_W223_M0.6510.94
128_F131_G0.6490.94
240_Q243_E0.6460.94
100_G103_L0.6450.94
71_I132_K0.6440.94
47_M79_R0.6430.94
256_P261_R0.6410.93
40_A287_Y0.6410.93
204_V208_T0.6410.93
290_G294_G0.6400.93
181_Y212_Q0.6350.93
136_M151_P0.6340.93
244_T248_D0.6300.93
87_T90_E0.6290.93
95_L99_R0.6290.93
82_I85_Y0.6280.93
261_R264_E0.6280.93
219_W228_G0.6210.92
61_S167_P0.6200.92
56_L133_S0.6190.92
106_L110_V0.6190.92
223_M227_L0.6180.92
205_V208_T0.6140.92
44_D79_R0.6100.92
192_V203_L0.6100.92
46_F204_V0.6100.92
258_G267_P0.6080.92
44_D287_Y0.6060.91
236_V241_H0.6050.91
165_A170_Y0.6040.91
205_V211_S0.6030.91
207_R266_Y0.6030.91
37_I149_F0.6010.91
299_A303_K0.6010.91
29_C66_N0.6000.91
58_L198_Q0.5990.91
235_L243_E0.5950.91
265_I294_G0.5930.91
250_Q254_E0.5920.90
35_R273_S0.5910.90
220_F225_R0.5900.90
239_V242_H0.5890.90
205_V261_R0.5890.90
222_R225_R0.5880.90
50_Q53_P0.5850.90
31_G60_T0.5850.90
251_Q256_P0.5830.90
173_G180_N0.5820.90
30_E207_R0.5790.89
271_L289_L0.5720.89
167_P184_G0.5720.89
218_Q222_R0.5690.89
33_G65_Q0.5640.88
76_G81_V0.5640.88
25_I28_V0.5610.88
253_I262_I0.5600.88
94_P300_T0.5590.88
195_A199_G0.5580.88
238_L241_H0.5580.88
90_E108_W0.5580.88
302_G305_L0.5570.88
219_W225_R0.5560.88
112_A115_S0.5560.88
65_Q109_L0.5560.88
209_V275_A0.5550.87
298_L303_K0.5540.87
41_G294_G0.5540.87
301_V305_L0.5540.87
109_L164_S0.5530.87
56_L198_Q0.5450.86
67_L71_I0.5450.86
257_P266_Y0.5440.86
193_K248_D0.5440.86
177_E180_N0.5420.86
225_R228_G0.5420.86
165_A186_I0.5420.86
43_L70_F0.5420.86
269_K289_L0.5410.86
64_A185_G0.5400.86
76_G85_Y0.5390.86
148_Y188_D0.5380.86
191_P274_I0.5370.86
214_Y221_K0.5370.86
59_G207_R0.5340.85
37_I170_Y0.5340.85
200_A203_L0.5330.85
85_Y88_K0.5310.85
296_Y303_K0.5300.85
259_K262_I0.5270.85
205_V262_I0.5250.84
35_R209_V0.5250.84
60_T146_P0.5230.84
257_P263_F0.5220.84
51_F298_L0.5190.84
213_M216_T0.5190.84
113_T117_M0.5180.84
265_I268_P0.5170.83
136_M197_R0.5150.83
234_P241_H0.5140.83
86_T90_E0.5140.83
44_D76_G0.5140.83
147_N152_T0.5140.83
243_E249_I0.5130.83
122_D127_L0.5130.83
75_P78_A0.5130.83
243_E250_Q0.5130.83
109_L170_Y0.5120.83
90_E93_D0.5100.83
68_S156_W0.5090.83
137_C194_E0.5080.82
61_S189_A0.5080.82
40_A80_K0.5080.82
61_S166_I0.5070.82
114_A155_N0.5070.82
130_S206_I0.5060.82
297_F304_L0.5060.82
136_M160_I0.5050.82
206_I210_P0.5050.82
157_L161_R0.5020.82
71_I75_P0.5010.82
265_I290_G0.5000.81
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4qmkA 2 0.7731 100 0.399 Contact Map
3tu3B 1 0.8291 100 0.401 Contact Map
4akfA 2 0.972 100 0.406 Contact Map
4pk9A 2 0.8263 100 0.413 Contact Map
1cjyA 1 0.8964 99.4 0.804 Contact Map
3ifrA 2 0.3109 42.7 0.952 Contact Map
3hz6A 1 0.2941 34.4 0.954 Contact Map
3h3nX 3 0.3333 30.8 0.955 Contact Map
2w40A 3 0.3305 28.6 0.956 Contact Map
2itmA 2 0.3277 28 0.956 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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