GREMLIN Database
YJIP - Putative uncharacterized protein YjiP
UniProt: P39387 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12577
Length: 306 (269)
Sequences: 1435 (1195)
Seq/√Len: 72.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
263_I267_L6.2671.00
267_L271_G4.3431.00
260_E264_L4.3101.00
266_L270_N3.6721.00
261_Q265_R3.6661.00
252_H258_K3.6351.00
265_R269_Q3.4151.00
283_L291_L3.4101.00
257_I261_Q3.3971.00
259_G263_I3.3461.00
256_Y260_E3.2441.00
247_I251_I3.1851.00
262_R266_L3.0871.00
264_L267_L3.0071.00
256_Y262_R3.0041.00
264_L268_L2.8581.00
257_I265_R2.8131.00
273_D276_W2.7791.00
267_L270_N2.7471.00
258_K262_R2.6831.00
261_Q269_Q2.6571.00
248_A251_I2.5871.00
84_Q94_R2.5741.00
46_K67_S2.4771.00
284_S287_Q2.4691.00
260_E266_L2.3051.00
264_L270_N2.2781.00
256_Y264_L2.1191.00
272_A276_W2.0011.00
260_E268_L1.9851.00
263_I271_G1.9551.00
84_Q91_M1.9461.00
278_Q288_M1.8431.00
91_M94_R1.8401.00
263_I268_L1.8391.00
259_G267_L1.8001.00
263_I266_L1.7921.00
287_Q290_A1.7631.00
243_R247_I1.7501.00
275_E279_K1.7351.00
262_R270_N1.7341.00
245_M251_I1.7131.00
277_I281_T1.7041.00
93_F107_I1.6701.00
277_I282_G1.6471.00
269_Q273_D1.6310.99
281_T288_M1.6150.99
246_T251_I1.5980.99
278_Q281_T1.5900.99
164_P167_E1.5800.99
268_L271_G1.5610.99
258_K266_L1.5600.99
260_E263_I1.5530.99
255_G259_G1.5370.99
277_I288_M1.5270.99
279_K283_L1.5220.99
264_L269_Q1.5190.99
249_E252_H1.5140.99
253_N257_I1.5120.99
277_I283_L1.4560.99
272_A280_I1.4520.99
279_K282_G1.4100.99
243_R251_I1.4010.98
265_R271_G1.3900.98
260_E267_L1.3760.98
174_V178_E1.3680.98
274_P277_I1.3670.98
260_E265_R1.3630.98
265_R270_N1.3620.98
278_Q285_A1.3570.98
272_A278_Q1.3540.98
257_I269_Q1.3540.98
96_M100_M1.3510.98
246_T249_E1.2820.97
253_N261_Q1.2810.97
285_A289_Q1.2660.97
274_P284_S1.2600.97
276_W288_M1.2550.97
241_R244_I1.2410.97
266_L269_Q1.2300.96
266_L271_G1.2190.96
103_M118_V1.2180.96
279_K288_M1.2130.96
270_N274_P1.2100.96
25_R29_E1.2080.96
267_L275_E1.2080.96
283_L288_M1.1910.96
80_V120_P1.1850.96
159_D162_V1.1480.95
247_I250_R1.1460.95
272_A288_M1.1290.94
244_I247_I1.1280.94
274_P278_Q1.1210.94
256_Y268_L1.1200.94
275_E285_A1.1190.94
277_I291_L1.1100.94
261_Q264_L1.1080.94
263_I270_N1.1080.94
242_E245_M1.1070.94
44_S69_K1.1040.94
248_A252_H1.1000.93
273_D278_Q1.0990.93
90_H140_E1.0900.93
69_K74_D1.0890.93
258_K270_N1.0850.93
47_L66_W1.0750.93
179_L182_K1.0730.93
281_T291_L1.0710.93
245_M249_E1.0640.92
251_I255_G1.0580.92
11_D15_K1.0580.92
52_F65_L1.0350.91
278_Q282_G1.0320.91
99_S120_P1.0310.91
265_R273_D1.0250.91
97_R104_Q1.0240.91
263_I269_Q1.0230.91
273_D279_K1.0180.91
101_A104_Q1.0160.90
28_M79_V1.0140.90
227_N231_S1.0140.90
136_C152_N1.0130.90
254_D258_K1.0060.90
99_S103_M1.0020.90
274_P279_K1.0010.90
15_K51_S0.9960.90
213_L217_I0.9960.90
99_S118_V0.9890.89
254_D262_R0.9850.89
271_G275_E0.9810.89
264_L271_G0.9780.89
281_T287_Q0.9660.88
67_S74_D0.9560.88
241_R247_I0.9550.87
14_F83_H0.9520.87
10_H14_F0.9420.87
284_S291_L0.9280.86
272_A279_K0.9220.86
244_I251_I0.9210.85
81_I92_A0.9130.85
240_H244_I0.9090.85
62_S65_L0.9080.85
257_I260_E0.9060.85
281_T284_S0.9050.84
134_S139_D0.9040.84
270_N279_K0.8950.84
80_V99_S0.8940.84
87_E133_W0.8900.83
95_L120_P0.8790.83
65_L102_V0.8760.83
93_F100_M0.8760.83
204_C207_D0.8710.82
165_D182_K0.8630.82
274_P287_Q0.8560.81
65_L76_Y0.8490.80
126_G159_D0.8440.80
119_I156_P0.8430.80
106_H116_P0.8420.80
277_I290_A0.8390.80
283_L287_Q0.8260.79
136_C154_A0.8260.79
60_L97_R0.8250.79
258_K261_Q0.8250.79
178_E181_Q0.8250.79
75_G105_R0.8250.79
85_S125_H0.8230.78
274_P288_M0.8220.78
274_P285_A0.8210.78
256_Y266_L0.8160.78
272_A275_E0.8160.78
280_I288_M0.8160.78
136_C139_D0.8130.78
60_L101_A0.8120.77
266_L282_G0.8110.77
282_G291_L0.8100.77
80_V95_L0.8000.76
245_M248_A0.7950.76
24_A66_W0.7940.76
12_A59_A0.7910.76
203_E217_I0.7910.76
285_A290_A0.7840.75
52_F102_V0.7840.75
253_N256_Y0.7820.75
260_E270_N0.7780.74
260_E269_Q0.7750.74
265_R268_L0.7740.74
165_D183_H0.7640.73
248_A254_D0.7640.73
264_L272_A0.7630.73
240_H247_I0.7630.73
210_I214_L0.7590.73
284_S289_Q0.7560.72
145_T154_A0.7530.72
249_E253_N0.7500.72
279_K291_L0.7460.71
242_E247_I0.7450.71
99_S153_A0.7440.71
29_E37_R0.7440.71
252_H256_Y0.7430.71
259_G264_L0.7420.71
228_E232_E0.7410.71
137_W153_A0.7330.70
261_Q266_L0.7320.70
226_F233_L0.7300.70
256_Y259_G0.7270.69
41_D44_S0.7250.69
276_W279_K0.7240.69
262_R267_L0.7230.69
277_I287_Q0.7220.69
122_L131_Y0.7210.69
274_P291_L0.7180.68
237_M240_H0.7180.68
27_F31_H0.7180.68
54_D57_L0.7170.68
267_L273_D0.7160.68
276_W280_I0.7140.68
210_I217_I0.7130.68
262_R265_R0.7130.68
28_M121_M0.7110.68
266_L274_P0.7100.67
18_L81_I0.7070.67
54_D123_F0.7060.67
273_D283_L0.7040.67
25_R40_C0.7040.67
269_Q275_E0.7010.66
181_Q185_R0.7000.66
139_D142_A0.6950.66
273_D277_I0.6940.66
275_E278_Q0.6930.66
273_D288_M0.6930.66
178_E182_K0.6930.66
82_E98_Y0.6910.65
279_K285_A0.6890.65
284_S290_A0.6880.65
267_L281_T0.6880.65
211_T215_N0.6870.65
70_T73_G0.6860.65
273_D290_A0.6840.65
95_L122_L0.6830.64
36_L119_I0.6810.64
133_W155_F0.6790.64
259_G266_L0.6780.64
244_I249_E0.6760.64
254_D257_I0.6750.64
60_L94_R0.6740.63
275_E291_L0.6740.63
131_Y151_Y0.6740.63
131_Y134_S0.6730.63
259_G262_R0.6720.63
243_R246_T0.6700.63
180_I183_H0.6700.63
13_L84_Q0.6620.62
267_L277_I0.6600.62
204_C219_L0.6550.61
89_I133_W0.6540.61
39_L142_A0.6540.61
96_M151_Y0.6510.61
275_E284_S0.6510.61
52_F101_A0.6500.61
282_G285_A0.6500.61
279_K290_A0.6490.61
213_L216_Y0.6430.60
27_F137_W0.6410.60
124_Y159_D0.6410.60
177_L180_I0.6410.60
138_L152_N0.6400.59
203_E206_N0.6370.59
174_V179_L0.6340.59
175_A179_L0.6330.59
284_S288_M0.6330.59
179_L183_H0.6310.58
121_M203_E0.6260.58
277_I284_S0.6220.57
272_A281_T0.6220.57
282_G288_M0.6180.57
15_K80_V0.6150.56
233_L236_R0.6130.56
51_S58_R0.6130.56
84_Q125_H0.6110.56
86_R94_R0.6100.56
278_Q284_S0.6100.56
62_S66_W0.6090.56
268_L272_A0.6090.56
62_S80_V0.6070.55
17_F23_T0.6040.55
278_Q283_L0.6030.55
261_Q268_L0.6030.55
122_L157_L0.6020.55
54_D61_H0.6010.55
35_D38_E0.5990.54
126_G131_Y0.5990.54
97_R101_A0.5990.54
196_L233_L0.5950.54
246_T252_H0.5950.54
277_I280_I0.5940.54
276_W286_E0.5940.54
10_H53_V0.5940.54
53_V59_A0.5930.54
120_P153_A0.5920.54
176_L180_I0.5890.53
51_S80_V0.5880.53
264_L281_T0.5860.53
167_E170_Q0.5840.53
231_S234_T0.5840.53
250_R253_N0.5830.53
99_S151_Y0.5830.53
18_L24_A0.5820.52
275_E283_L0.5810.52
206_N209_Q0.5800.52
228_E231_S0.5800.52
18_L30_I0.5800.52
218_L221_G0.5790.52
28_M38_E0.5780.52
278_Q289_Q0.5760.52
36_L125_H0.5730.51
18_L83_H0.5710.51
238_P242_E0.5710.51
25_R42_L0.5700.51
226_F254_D0.5690.51
271_G279_K0.5690.51
267_L280_I0.5690.51
36_L196_L0.5690.51
106_H155_F0.5690.51
47_L105_R0.5670.51
10_H120_P0.5660.50
240_H245_M0.5660.50
287_Q291_L0.5650.50
125_H181_Q0.5640.50
251_I254_D0.5640.50
269_Q274_P0.5640.50
50_A61_H0.5610.50
256_Y261_Q0.5610.50
234_T284_S0.5600.50
27_F158_V0.5560.49
180_I184_I0.5560.49
260_E271_G0.5550.49
242_E246_T0.5530.49
231_S235_R0.5520.49
33_P36_L0.5490.48
45_L103_M0.5470.48
257_I262_R0.5460.48
199_L203_E0.5450.48
272_A277_I0.5440.48
273_D280_I0.5440.48
102_V118_V0.5440.48
203_E207_D0.5430.48
268_L275_E0.5410.47
65_L160_V0.5410.47
214_L218_L0.5410.47
279_K287_Q0.5390.47
210_I216_Y0.5380.47
96_M153_A0.5370.47
247_I252_H0.5370.47
240_H243_R0.5360.47
260_E272_A0.5360.47
92_A155_F0.5360.47
123_F126_G0.5350.47
99_S137_W0.5340.46
286_E290_A0.5330.46
276_W282_G0.5320.46
68_V162_V0.5320.46
226_F250_R0.5320.46
170_Q228_E0.5290.46
205_A209_Q0.5280.46
93_F158_V0.5260.45
44_S68_V0.5260.45
83_H125_H0.5250.45
14_F18_L0.5240.45
122_L133_W0.5240.45
209_Q213_L0.5240.45
191_G226_F0.5230.45
240_H254_D0.5220.45
204_C215_N0.5210.45
49_S57_L0.5210.45
35_D154_A0.5200.45
230_I234_T0.5200.45
81_I84_Q0.5190.45
68_V108_E0.5180.45
122_L137_W0.5180.45
266_L289_Q0.5180.45
57_L100_M0.5160.44
253_N287_Q0.5160.44
24_A32_L0.5160.44
273_D281_T0.5150.44
175_A181_Q0.5150.44
36_L62_S0.5140.44
270_N275_E0.5140.44
120_P125_H0.5130.44
27_F30_I0.5130.44
117_L131_Y0.5130.44
26_D30_I0.5100.44
117_L141_F0.5100.44
177_L192_L0.5090.43
79_V121_M0.5080.43
26_D29_E0.5070.43
16_T108_E0.5060.43
191_G194_D0.5060.43
274_P290_A0.5040.43
65_L106_H0.5030.43
15_K88_D0.5030.43
35_D145_T0.5030.43
200_L212_A0.5010.42
70_T150_L0.5000.42
274_P283_L0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1jkoC 1 0.1503 23.1 0.956 Contact Map
2m8eA 1 0.1863 23 0.956 Contact Map
4dyqA 5 0.1765 17.3 0.958 Contact Map
2x48A 1 0.1667 17 0.958 Contact Map
1z6rA 3 0.1634 10.9 0.962 Contact Map
3c1dA 2 0.3987 10.1 0.962 Contact Map
3bzcA 1 0.2288 9.9 0.962 Contact Map
2bcqA 1 0.3627 8.7 0.963 Contact Map
1tc3C 1 0.1667 8.5 0.963 Contact Map
1hx8A 1 0.1993 8.3 0.964 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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