GREMLIN Database
YJIN - Uncharacterized protein YjiN
UniProt: P39385 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12575
Length: 426 (397)
Sequences: 1277 (932)
Seq/√Len: 46.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
80_N83_R6.6671.00
75_A78_P4.9271.00
66_P69_I4.5301.00
43_I405_G3.5431.00
283_D286_K3.5321.00
112_A347_N3.4361.00
47_A405_G3.3461.00
389_I393_L3.3091.00
39_G416_Q3.1951.00
25_F415_S2.9791.00
24_T44_A2.8981.00
378_A382_S2.8521.00
107_R351_E2.8461.00
392_D399_N2.7871.00
367_R371_D2.7431.00
38_S412_Y2.7251.00
270_D274_N2.6551.00
370_S374_K2.6211.00
31_L34_N2.5841.00
110_E347_N2.5721.00
86_E374_K2.5051.00
392_D397_R2.3341.00
64_R69_I2.2841.00
64_R70_I2.2831.00
27_V31_L2.1421.00
110_E113_L2.1361.00
26_V30_F2.0851.00
85_G373_V2.0701.00
20_I24_T2.0471.00
116_G333_G2.0200.99
88_L373_V2.0170.99
17_L21_A1.9970.99
174_E273_K1.9880.99
45_E73_H1.9710.99
39_G412_Y1.9640.99
93_Q366_T1.9360.99
17_L20_I1.9220.99
182_H262_D1.9130.99
34_N37_V1.8900.99
198_Q243_N1.8760.99
51_A401_T1.8550.99
64_R72_R1.8460.99
73_H395_F1.8290.99
84_I93_Q1.8280.99
308_E312_V1.8170.99
55_W397_R1.7960.99
105_L108_R1.7870.99
125_A160_I1.7860.99
194_I198_Q1.7810.99
68_P72_R1.7800.99
86_E370_S1.7720.99
12_R16_S1.7280.98
52_L407_I1.7180.98
45_E49_V1.6870.98
329_G332_F1.6630.98
43_I409_L1.6530.98
383_R387_L1.6480.98
35_F39_G1.6390.98
63_R78_P1.6270.97
46_A51_A1.6180.97
241_A245_L1.6100.97
54_D60_A1.6000.97
96_F376_W1.5910.97
20_I23_A1.5900.97
233_H237_L1.5900.97
377_D380_D1.5810.97
395_F398_V1.5700.97
21_A47_A1.5680.97
176_M181_R1.5680.97
54_D397_R1.5470.96
49_V395_F1.5250.96
53_A60_A1.5160.96
45_E96_F1.5130.96
181_R184_V1.5110.96
241_A244_S1.5040.96
399_N411_L1.4960.96
95_K384_Q1.4930.96
16_S20_I1.4780.95
186_L261_F1.4700.95
19_L23_A1.4680.95
53_A397_R1.4560.95
126_R326_A1.4560.95
27_V34_N1.4540.95
227_T231_G1.4470.95
340_D344_A1.4240.94
51_A145_D1.4220.94
50_G57_A1.4220.94
43_I47_A1.4160.94
191_A236_E1.4100.94
55_W393_L1.4080.94
81_K373_V1.4040.94
400_G404_G1.3980.94
39_G43_I1.3870.94
54_D399_N1.3870.94
12_R19_L1.3840.94
164_D283_D1.3830.93
284_A297_R1.3790.93
261_F265_T1.3760.93
389_I397_R1.3710.93
64_R68_P1.3630.93
161_D291_E1.3410.92
46_A392_D1.3340.92
74_T397_R1.3340.92
23_A27_V1.3260.92
187_D258_R1.3250.92
235_A239_S1.3220.92
88_L91_F1.3190.92
54_D74_T1.3160.92
53_A399_N1.3070.91
404_G408_G1.2950.91
218_H231_G1.2920.91
74_T399_N1.2880.91
386_E393_L1.2840.91
49_V368_H1.2730.90
22_A48_M1.2700.90
66_P258_R1.2620.90
313_D316_S1.2600.90
71_S74_T1.2560.90
194_I246_L1.2550.90
376_W395_F1.2530.90
91_F376_W1.2450.89
217_E241_A1.2440.89
55_W60_A1.2420.89
53_A74_T1.2420.89
79_R104_A1.2380.89
284_A288_Y1.2350.89
239_S243_N1.2280.89
30_F37_V1.2230.88
400_G408_G1.2210.88
386_E397_R1.2180.88
68_P71_S1.2180.88
74_T392_D1.2180.88
218_H221_K1.2140.88
190_I246_L1.2130.88
76_I381_M1.2120.88
50_G62_F1.2090.88
89_G362_S1.2080.88
91_F401_T1.2070.88
24_T28_T1.2040.88
116_G120_S1.1970.87
334_E338_A1.1910.87
386_E394_Q1.1890.87
77_I169_S1.1860.87
89_G372_T1.1830.87
56_F60_A1.1810.87
55_W389_I1.1770.86
42_A45_E1.1750.86
46_A56_F1.1740.86
76_I392_D1.1730.86
403_V407_I1.1700.86
391_K395_F1.1660.86
188_T192_Q1.1590.86
25_F32_P1.1560.85
157_H296_N1.1530.85
194_I243_N1.1520.85
60_A74_T1.1510.85
355_H385_I1.1500.85
21_A361_F1.1500.85
386_E390_G1.1440.85
22_A29_L1.1430.85
43_I412_Y1.1410.85
378_A386_E1.1370.84
55_W386_E1.1330.84
254_A259_H1.1300.84
395_F399_N1.1210.84
60_A397_R1.1190.83
101_S105_L1.1150.83
28_T41_K1.1130.83
233_H236_E1.1100.83
267_A271_K1.1060.83
29_L32_P1.1060.83
125_A333_G1.1050.83
213_W241_A1.1010.82
170_A273_K1.0970.82
81_K376_W1.0960.82
39_G409_L1.0940.82
40_V44_A1.0870.82
222_A231_G1.0860.82
401_T412_Y1.0850.81
242_V256_Q1.0820.81
12_R15_L1.0790.81
89_G388_N1.0780.81
60_A399_N1.0780.81
345_S349_H1.0710.81
406_C417_L1.0710.81
99_T359_P1.0680.80
125_A129_G1.0650.80
226_P229_W1.0650.80
20_I297_R1.0650.80
191_A250_S1.0650.80
89_G370_S1.0650.80
158_R413_L1.0620.80
265_T305_D1.0590.80
386_E401_T1.0540.80
76_I79_R1.0430.79
125_A330_Q1.0400.79
53_A56_F1.0390.79
75_A339_D1.0350.78
397_R403_V1.0330.78
140_L244_S1.0310.78
148_I304_G1.0250.78
59_V398_V1.0250.78
130_Q322_K1.0220.77
211_V310_L1.0120.77
280_A287_S1.0100.77
46_A74_T1.0100.77
394_Q399_N1.0080.76
13_L16_S1.0080.76
93_Q363_A1.0020.76
81_K387_L0.9990.76
334_E337_I0.9950.75
72_R75_A0.9860.75
369_I401_T0.9850.75
160_I417_L0.9770.74
54_D392_D0.9760.74
54_D73_H0.9730.74
73_H109_H0.9720.74
84_I386_E0.9720.74
213_W217_E0.9700.74
399_N403_V0.9690.74
303_W376_W0.9660.73
33_P37_V0.9610.73
77_I84_I0.9570.73
247_D251_R0.9540.72
54_D75_A0.9520.72
17_L401_T0.9510.72
386_E399_N0.9480.72
42_A395_F0.9480.72
96_F362_S0.9460.72
90_Q106_I0.9450.72
169_S346_L0.9450.72
74_T386_E0.9350.71
25_F48_M0.9340.71
42_A46_A0.9300.70
49_V56_F0.9260.70
384_Q388_N0.9250.70
56_F390_G0.9240.70
20_I33_P0.9210.70
76_I314_I0.9210.70
70_I75_A0.9200.70
59_V72_R0.9190.69
115_I357_V0.9190.69
74_T382_S0.9180.69
245_L269_I0.9140.69
71_S75_A0.9100.69
46_A399_N0.9100.69
405_G410_I0.9090.69
73_H397_R0.9090.69
53_A73_H0.9070.68
15_L19_L0.9060.68
53_A392_D0.9040.68
73_H392_D0.9040.68
53_A75_A0.9020.68
89_G98_D0.9010.68
339_D344_A0.8970.68
407_I411_L0.8950.67
371_D374_K0.8940.67
385_I392_D0.8940.67
73_H399_N0.8900.67
56_F74_T0.8890.67
396_I404_G0.8880.67
64_R71_S0.8880.67
51_A405_G0.8870.67
364_F367_R0.8870.67
85_G89_G0.8850.67
70_I73_H0.8850.67
54_D58_V0.8780.66
42_A412_Y0.8740.66
86_E347_N0.8730.65
93_Q358_A0.8700.65
56_F73_H0.8680.65
373_V381_M0.8670.65
373_V376_W0.8650.65
32_P41_K0.8620.65
110_E343_R0.8610.64
394_Q397_R0.8520.64
72_R376_W0.8470.63
126_R139_F0.8450.63
121_Q124_N0.8440.63
72_R386_E0.8400.62
81_K293_E0.8400.62
87_N388_N0.8400.62
381_M385_I0.8360.62
42_A73_H0.8360.62
197_L310_L0.8350.62
111_P118_W0.8330.62
73_H382_S0.8310.62
104_A375_S0.8310.62
108_R414_L0.8300.62
57_A62_F0.8290.61
105_L391_K0.8270.61
249_I257_I0.8250.61
396_I399_N0.8200.61
81_K85_G0.8180.60
166_S282_A0.8180.60
45_E56_F0.8170.60
39_G413_L0.8150.60
14_A398_V0.8140.60
158_R410_I0.8130.60
73_H96_F0.8130.60
216_S341_A0.8130.60
55_W59_V0.8110.60
411_L414_L0.8010.59
376_W392_D0.8000.59
412_Y416_Q0.7990.59
88_L210_I0.7980.59
59_V68_P0.7970.58
231_G373_V0.7930.58
69_I72_R0.7930.58
154_R243_N0.7920.58
91_F369_I0.7870.57
66_P74_T0.7870.57
210_I238_V0.7870.57
84_I376_W0.7870.57
406_C410_I0.7860.57
16_S19_L0.7840.57
56_F88_L0.7840.57
90_Q94_E0.7840.57
58_V397_R0.7840.57
273_K278_M0.7820.57
53_A58_V0.7810.57
60_A73_H0.7810.57
96_F401_T0.7800.57
56_F399_N0.7750.56
92_V229_W0.7740.56
301_E365_L0.7710.56
412_Y415_S0.7710.56
21_A380_D0.7690.56
44_A382_S0.7650.55
374_K389_I0.7640.55
197_L210_I0.7630.55
118_W124_N0.7610.55
362_S370_S0.7580.55
330_Q334_E0.7580.55
236_E240_D0.7580.55
39_G66_P0.7570.55
55_W399_N0.7550.54
55_W74_T0.7540.54
189_L220_L0.7540.54
56_F397_R0.7540.54
393_L397_R0.7490.54
385_I399_N0.7480.54
117_N308_E0.7390.53
82_D374_K0.7390.53
236_E248_D0.7390.53
81_K401_T0.7390.53
95_K354_A0.7310.52
115_I198_Q0.7290.52
394_Q401_T0.7270.52
106_I358_A0.7200.51
367_R370_S0.7180.51
32_P35_F0.7170.51
66_P397_R0.7160.50
54_D59_V0.7150.50
46_A394_Q0.7150.50
376_W401_T0.7140.50
115_I118_W0.7100.50
45_E54_D0.7080.50
23_A178_K0.7070.50
95_K373_V0.7060.49
354_A381_M0.7050.49
185_L190_I0.7050.49
46_A54_D0.7040.49
386_E392_D0.7030.49
147_R290_K0.7020.49
392_D395_F0.7010.49
13_L24_T0.7010.49
55_W390_G0.7000.49
95_K237_L0.6980.49
378_A403_V0.6980.49
15_L20_I0.6980.49
304_G340_D0.6960.48
396_I403_V0.6920.48
333_G336_L0.6920.48
100_Q122_P0.6910.48
386_E398_V0.6910.48
392_D411_L0.6910.48
89_G93_Q0.6890.48
46_A388_N0.6880.48
115_I120_S0.6880.48
112_A115_I0.6860.47
373_V388_N0.6860.47
53_A59_V0.6860.47
76_I102_L0.6850.47
228_E231_G0.6850.47
51_A397_R0.6840.47
44_A66_P0.6840.47
289_L295_F0.6840.47
80_N84_I0.6830.47
281_R284_A0.6830.47
84_I398_V0.6810.47
44_A96_F0.6790.47
335_T339_D0.6770.47
42_A51_A0.6770.47
193_L197_L0.6730.46
289_L311_K0.6720.46
192_Q407_I0.6720.46
271_K275_D0.6720.46
312_V383_R0.6720.46
92_V380_D0.6710.46
102_L374_K0.6700.46
200_D231_G0.6670.46
173_L297_R0.6670.46
250_S262_D0.6670.46
80_N381_M0.6650.45
14_A67_I0.6630.45
120_S318_D0.6630.45
369_I393_L0.6610.45
31_L37_V0.6600.45
195_A300_S0.6600.45
28_T31_L0.6600.45
254_A402_L0.6600.45
94_E380_D0.6550.44
162_K189_L0.6540.44
259_H409_L0.6540.44
388_N399_N0.6530.44
120_S337_I0.6530.44
220_L265_T0.6520.44
60_A75_A0.6520.44
163_V169_S0.6520.44
54_D66_P0.6510.44
102_L113_L0.6510.44
55_W91_F0.6500.44
26_V338_A0.6490.44
84_I87_N0.6490.44
96_F384_Q0.6470.44
92_V368_H0.6470.44
358_A372_T0.6450.43
99_T349_H0.6420.43
405_G412_Y0.6420.43
14_A68_P0.6420.43
99_T103_V0.6380.43
74_T403_V0.6380.43
384_Q401_T0.6370.43
100_Q334_E0.6360.43
171_L312_V0.6360.43
288_Y306_L0.6360.43
74_T388_N0.6330.42
51_A392_D0.6330.42
42_A49_V0.6310.42
60_A392_D0.6300.42
237_L373_V0.6280.42
116_G336_L0.6250.42
91_F384_Q0.6250.42
45_E53_A0.6240.41
59_V386_E0.6230.41
396_I400_G0.6220.41
45_E386_E0.6220.41
117_N132_L0.6210.41
237_L241_A0.6210.41
14_A59_V0.6210.41
46_A397_R0.6210.41
214_L232_E0.6190.41
327_R330_Q0.6180.41
54_D382_S0.6170.41
70_I74_T0.6160.41
89_G192_Q0.6150.41
13_L17_L0.6150.41
369_I380_D0.6150.41
132_L135_I0.6140.40
98_D388_N0.6140.40
16_S24_T0.6110.40
177_T266_F0.6110.40
52_L134_Q0.6100.40
29_L49_V0.6080.40
90_Q193_L0.6050.40
34_N43_I0.6050.40
284_A323_E0.6040.40
46_A53_A0.6040.40
46_A73_H0.6010.39
18_L51_A0.5990.39
54_D386_E0.5980.39
55_W392_D0.5980.39
24_T402_L0.5960.39
160_I294_A0.5960.39
194_I250_S0.5940.39
74_T411_L0.5930.38
171_L325_I0.5920.38
287_S334_E0.5920.38
49_V73_H0.5910.38
381_M388_N0.5910.38
51_A412_Y0.5880.38
146_A305_D0.5880.38
76_I395_F0.5880.38
289_L347_N0.5870.38
162_K285_V0.5860.38
297_R300_S0.5840.38
60_A411_L0.5820.37
67_I70_I0.5820.37
54_D411_L0.5800.37
59_V70_I0.5780.37
214_L219_P0.5770.37
84_I388_N0.5750.37
76_I396_I0.5740.37
113_L120_S0.5740.37
220_L229_W0.5730.37
81_K378_A0.5730.37
39_G407_I0.5730.37
196_L213_W0.5730.37
118_W350_L0.5710.36
51_A399_N0.5700.36
110_E284_A0.5700.36
378_A401_T0.5690.36
22_A31_L0.5680.36
250_S365_L0.5680.36
266_F307_R0.5660.36
79_R190_I0.5660.36
188_T231_G0.5650.36
43_I70_I0.5640.36
72_R395_F0.5640.36
56_F392_D0.5630.36
146_A150_R0.5630.36
113_L290_K0.5630.36
82_D378_A0.5610.36
191_A195_A0.5610.36
20_I254_A0.5600.35
237_L243_N0.5590.35
392_D396_I0.5580.35
386_E389_I0.5580.35
358_A361_F0.5560.35
144_D147_R0.5540.35
51_A59_V0.5530.35
388_N407_I0.5530.35
31_L152_L0.5510.35
193_L302_L0.5500.35
382_S403_V0.5500.35
53_A66_P0.5470.34
111_P117_N0.5460.34
235_A292_D0.5450.34
60_A382_S0.5450.34
154_R300_S0.5430.34
82_D279_A0.5420.34
56_F378_A0.5410.34
199_R365_L0.5400.34
272_L295_F0.5390.34
395_F412_Y0.5380.33
141_E414_L0.5380.33
258_R390_G0.5370.33
158_R179_N0.5360.33
113_L343_R0.5350.33
352_Q383_R0.5340.33
294_A310_L0.5340.33
16_S23_A0.5340.33
364_F395_F0.5330.33
398_V403_V0.5330.33
354_A366_T0.5330.33
173_L336_L0.5320.33
33_P280_A0.5320.33
53_A388_N0.5310.33
330_Q333_G0.5310.33
78_P379_R0.5300.33
260_A263_R0.5290.33
176_M182_H0.5280.33
242_V282_A0.5270.32
120_S334_E0.5270.32
123_E208_Q0.5270.32
397_R411_L0.5260.32
14_A29_L0.5250.32
146_A154_R0.5220.32
85_G91_F0.5210.32
30_F199_R0.5210.32
139_F352_Q0.5200.32
46_A408_G0.5190.32
53_A386_E0.5180.32
46_A401_T0.5180.32
113_L117_N0.5180.32
39_G414_L0.5180.32
195_A263_R0.5170.32
54_D388_N0.5170.32
165_L191_A0.5170.32
304_G315_N0.5160.32
359_P365_L0.5150.31
268_L273_K0.5150.31
55_W398_V0.5150.31
24_T382_S0.5150.31
53_A411_L0.5150.31
236_E244_S0.5150.31
283_D414_L0.5140.31
101_S372_T0.5130.31
140_L197_L0.5120.31
11_K365_L0.5120.31
346_L350_L0.5110.31
29_L41_K0.5100.31
15_L21_A0.5100.31
98_D382_S0.5100.31
53_A382_S0.5090.31
102_L134_Q0.5090.31
376_W399_N0.5090.31
118_W319_S0.5090.31
27_V30_F0.5080.31
192_Q229_W0.5080.31
183_Q262_D0.5080.31
93_Q372_T0.5050.31
78_P408_G0.5010.30
73_H85_G0.5010.30
89_G237_L0.5000.30
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4atgA 1 0.3592 46.6 0.962 Contact Map
2vj4A 1 0.554 20.7 0.969 Contact Map
2bnlA 2 0.2958 18.5 0.969 Contact Map
2i2oA 2 0.4742 17.6 0.97 Contact Map
2l0eA 1 0.0728 16.1 0.97 Contact Map
3bwtA 1 0.5164 15.3 0.971 Contact Map
2i68A 2 0.1221 14.8 0.971 Contact Map
2kluA 1 0.0869 14.1 0.971 Contact Map
3vvyA 2 0.4366 11.3 0.972 Contact Map
4dhxB 1 0.216 9.3 0.973 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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