GREMLIN Database
YJIL - Uncharacterized protein YjiL
UniProt: P39383 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12573
Length: 255 (247)
Sequences: 2172 (1390)
Seq/√Len: 88.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
20_A23_V6.2411.00
35_R38_T4.1631.00
17_I24_I4.0861.00
82_L250_R4.0851.00
5_I18_L3.2621.00
151_V180_A3.0921.00
90_A205_P3.0551.00
148_T217_K3.0091.00
27_R238_F2.9501.00
140_S143_Q2.8371.00
149_E179_E2.7331.00
28_F46_T2.5091.00
17_I242_I2.4761.00
139_T147_I2.4571.00
168_A181_I2.4091.00
3_Y25_T2.3891.00
74_V247_I2.3731.00
91_T207_L2.3151.00
18_L47_L2.3071.00
150_N180_A2.2621.00
220_R224_S2.2621.00
80_H240_G2.2341.00
22_G249_Q2.1931.00
143_Q146_S2.1291.00
212_V218_F2.1201.00
22_G86_F2.0891.00
153_P183_A2.0491.00
220_R223_E2.0151.00
223_E229_P1.9981.00
144_L182_L1.9451.00
187_N224_S1.9011.00
41_T45_E1.8271.00
16_G43_A1.8261.00
213_S236_A1.8041.00
84_A94_V1.8041.00
85_R90_A1.7771.00
27_R235_D1.7701.00
204_A228_M1.7671.00
82_L86_F1.7601.00
176_V180_A1.7241.00
187_N225_H1.7211.00
156_I164_A1.6831.00
146_S149_E1.6641.00
202_C206_I1.6621.00
206_I228_M1.6561.00
172_R181_I1.5931.00
88_A207_L1.5911.00
95_I197_I1.5831.00
58_T248_G1.5791.00
38_T42_E1.5751.00
92_R203_E1.5511.00
42_E46_T1.5311.00
58_T72_K1.5271.00
146_S216_Q1.5241.00
5_I57_L1.5061.00
3_Y54_T1.5041.00
56_F248_G1.5031.00
80_H239_A1.5001.00
76_E101_D1.4821.00
132_V161_T1.4740.99
14_T32_T1.4670.99
147_I179_E1.4610.99
58_T244_A1.4550.99
145_D217_K1.4460.99
11_S101_D1.4320.99
16_G47_L1.4060.99
5_I47_L1.3870.99
177_A180_A1.3590.99
106_Q203_E1.3560.99
150_N183_A1.3460.99
78_S247_I1.3450.99
42_E45_E1.3420.99
95_I193_S1.3320.99
40_I67_V1.3280.99
3_Y18_L1.3000.99
205_P231_N1.2970.99
150_N153_P1.2900.99
77_I113_L1.2870.99
190_A225_H1.2810.99
4_S249_Q1.2740.98
99_G103_K1.2680.98
133_I168_A1.2670.98
7_I67_V1.2450.98
19_L242_I1.2350.98
76_E103_K1.2310.98
92_R205_P1.1990.98
32_T75_T1.1980.98
80_H209_T1.1940.98
191_R225_H1.1870.98
148_T186_I1.1850.98
108_D112_N1.1710.97
106_Q201_S1.1620.97
19_L245_A1.1550.97
16_G26_R1.1520.97
153_P184_G1.1410.97
24_I242_I1.1320.97
95_I104_V1.1120.96
62_Y96_D1.1000.96
148_T182_L1.0870.96
152_T180_A1.0860.96
87_L239_A1.0810.96
154_H176_V1.0760.96
145_D215_C1.0720.96
155_A191_R1.0710.96
145_D186_I1.0640.95
217_K221_M1.0580.95
214_H237_Q1.0540.95
101_D118_M1.0510.95
45_E49_E1.0430.95
4_S248_G1.0240.94
76_E99_G1.0190.94
123_A192_R1.0160.94
26_R50_G1.0100.94
26_R47_L1.0080.94
186_I217_K1.0050.94
82_L247_I1.0020.94
219_A232_T1.0010.94
118_M126_T0.9980.94
145_D216_Q0.9980.94
105_I113_L0.9980.94
186_I218_F0.9860.93
62_Y101_D0.9810.93
86_F246_V0.9790.93
155_A187_N0.9700.93
151_V177_A0.9680.92
59_L70_A0.9650.92
233_H236_A0.9640.92
139_T143_Q0.9640.92
103_K118_M0.9490.92
86_F242_I0.9470.92
190_A218_F0.9410.91
134_S148_T0.9330.91
92_R204_A0.9330.91
48_R51_L0.9310.91
88_A205_P0.9300.91
30_V39_A0.9200.90
168_A191_R0.9140.90
190_A221_M0.9080.90
30_V42_E0.9020.90
9_S14_T0.8920.89
108_D114_C0.8820.89
20_A25_T0.8770.88
212_V215_C0.8710.88
77_I118_M0.8660.88
236_A239_A0.8600.87
88_A91_T0.8560.87
84_A207_L0.8520.87
157_T167_E0.8480.87
81_G113_L0.8430.86
91_T107_L0.8380.86
97_I193_S0.8370.86
235_D242_I0.8340.86
7_I59_L0.8330.86
4_S56_F0.8310.85
82_L85_R0.8270.85
91_T231_N0.8190.85
88_A231_N0.8190.85
43_A47_L0.8160.84
133_I182_L0.8140.84
5_I54_T0.8120.84
133_I161_T0.8110.84
62_Y103_K0.8100.84
192_R196_F0.8100.84
7_I16_G0.8100.84
115_D200_L0.8010.83
133_I185_V0.7960.83
62_Y100_Q0.7950.83
64_R118_M0.7880.82
96_D209_T0.7880.82
209_T239_A0.7870.82
99_G126_T0.7860.82
18_L51_L0.7860.82
84_A239_A0.7810.82
87_L242_I0.7810.82
12_T131_E0.7800.82
102_S208_F0.7730.81
21_D45_E0.7690.81
194_A222_L0.7690.81
223_E230_V0.7690.81
133_I172_R0.7650.80
95_I206_I0.7650.80
74_V171_L0.7620.80
11_S103_K0.7570.80
4_S19_L0.7570.80
45_E48_R0.7570.80
121_K196_F0.7530.79
105_I116_F0.7500.79
214_H236_A0.7490.79
186_I215_C0.7420.78
130_L212_V0.7380.78
187_N221_M0.7380.78
194_A206_I0.7370.78
19_L22_G0.7310.77
208_F212_V0.7310.77
83_G121_K0.7270.77
208_F219_A0.7250.77
194_A197_I0.7250.77
133_I136_T0.7210.76
51_L54_T0.7210.76
56_F72_K0.7210.76
29_L238_F0.7160.76
26_R51_L0.7160.76
165_E169_I0.7160.76
6_G10_G0.7150.76
22_G246_V0.7150.76
12_T31_P0.7120.75
106_Q115_D0.7070.75
17_I27_R0.7070.75
46_T50_G0.7050.75
16_G28_F0.7040.74
38_T41_T0.6990.74
51_L224_S0.6950.74
214_H235_D0.6930.73
97_I218_F0.6930.73
64_R73_Q0.6900.73
26_R46_T0.6880.73
120_D196_F0.6790.72
235_D238_F0.6780.72
39_A43_A0.6760.71
216_Q220_R0.6740.71
25_T86_F0.6730.71
83_G239_A0.6720.71
62_Y128_R0.6720.71
133_I189_M0.6710.71
80_H101_D0.6680.71
7_I43_A0.6670.70
129_F181_I0.6670.70
60_T240_G0.6660.70
170_S196_F0.6660.70
67_V70_A0.6630.70
187_N191_R0.6620.70
96_D240_G0.6600.70
81_G107_L0.6590.70
124_A156_I0.6580.69
95_I190_A0.6570.69
100_Q120_D0.6560.69
15_K185_V0.6530.69
227_R250_R0.6530.69
126_T164_A0.6510.69
12_T101_D0.6490.68
40_I44_W0.6480.68
64_R77_I0.6450.68
87_L246_V0.6430.68
30_V43_A0.6420.68
11_S76_E0.6410.67
171_L181_I0.6390.67
85_R107_L0.6340.67
96_D168_A0.6310.66
45_E250_R0.6300.66
62_Y118_M0.6280.66
189_M218_F0.6280.66
144_L185_V0.6260.66
121_K128_R0.6250.65
157_T164_A0.6240.65
183_A221_M0.6220.65
190_A222_L0.6220.65
205_P229_P0.6210.65
167_E170_S0.6210.65
159_M170_S0.6190.65
62_Y99_G0.6190.65
105_I199_R0.6180.65
5_I26_R0.6180.65
48_R52_E0.6180.65
75_T173_S0.6170.65
77_I100_Q0.6160.64
15_K238_F0.6150.64
124_A161_T0.6150.64
171_L184_G0.6120.64
14_T39_A0.6110.64
39_A42_E0.6100.64
64_R126_T0.6100.64
108_D111_G0.6080.63
65_Q68_D0.6060.63
41_T51_L0.6030.63
121_K166_S0.6020.63
94_V207_L0.6000.62
159_M202_C0.5990.62
9_S40_I0.5990.62
136_T185_V0.5990.62
74_V79_C0.5990.62
32_T173_S0.5970.62
23_V152_T0.5960.62
14_T79_C0.5900.61
14_T40_I0.5900.61
238_F242_I0.5900.61
241_A245_A0.5880.61
19_L249_Q0.5880.61
9_S67_V0.5880.61
12_T130_L0.5880.61
100_Q119_N0.5860.61
167_E171_L0.5850.60
37_A41_T0.5840.60
19_L86_F0.5830.60
183_A217_K0.5830.60
23_V48_R0.5820.60
48_R53_T0.5770.59
96_D103_K0.5750.59
92_R108_D0.5730.59
55_P245_A0.5730.59
134_S145_D0.5720.59
190_A194_A0.5720.59
129_F159_M0.5680.58
22_G250_R0.5670.58
79_C244_A0.5660.58
132_V169_I0.5660.58
27_R236_A0.5640.58
100_Q165_E0.5630.58
130_L185_V0.5620.57
97_I173_S0.5560.57
216_Q232_T0.5560.57
121_K170_S0.5550.56
134_S240_G0.5550.56
77_I105_I0.5530.56
232_T236_A0.5510.56
43_A46_T0.5500.56
104_V198_A0.5500.56
120_D169_I0.5480.56
222_L246_V0.5470.55
163_F181_I0.5440.55
14_T43_A0.5430.55
59_L67_V0.5420.55
123_A213_S0.5410.55
104_V196_F0.5410.55
40_I48_R0.5410.55
45_E224_S0.5410.55
42_E149_E0.5400.54
161_T218_F0.5400.54
4_S20_A0.5390.54
221_M224_S0.5370.54
80_H96_D0.5360.54
166_S169_I0.5360.54
132_V165_E0.5350.54
28_F50_G0.5350.54
28_F43_A0.5320.53
153_P180_A0.5320.53
94_V107_L0.5310.53
104_V193_S0.5310.53
161_T184_G0.5300.53
85_R88_A0.5300.53
24_I27_R0.5300.53
90_A231_N0.5300.53
100_Q132_V0.5270.53
23_V151_V0.5270.53
131_E135_R0.5260.53
208_F213_S0.5260.53
104_V199_R0.5240.52
24_I247_I0.5240.52
58_T247_I0.5240.52
225_H228_M0.5210.52
52_E55_P0.5210.52
24_I38_T0.5190.52
64_R100_Q0.5180.51
136_T165_E0.5160.51
18_L54_T0.5160.51
120_D167_E0.5150.51
93_A104_V0.5120.51
157_T196_F0.5090.50
123_A165_E0.5080.50
46_T49_E0.5070.50
142_E249_Q0.5070.50
90_A204_A0.5070.50
120_D199_R0.5060.50
11_S99_G0.5060.50
147_I182_L0.5060.50
62_Y158_S0.5030.49
12_T99_G0.5030.49
69_F108_D0.5030.49
133_I170_S0.5000.49
77_I80_H0.5000.49
104_V113_L0.5000.49
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4m7xA 2 0.9294 100 0.456 Contact Map
2i7nA 2 0.9059 100 0.503 Contact Map
4ehuA 2 0.9961 100 0.555 Contact Map
1huxA 2 0.9882 100 0.578 Contact Map
2ivnA 1 0.9804 100 0.631 Contact Map
3enoA 1 0.9882 100 0.631 Contact Map
3en9A 1 0.9804 100 0.64 Contact Map
3zeuB 1 0.9765 100 0.645 Contact Map
4mo4A 2 0.9529 100 0.673 Contact Map
3cqyA 3 0.9804 100 0.675 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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