GREMLIN Database
YJIK - Uncharacterized protein YjiK
UniProt: P39382 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12572
Length: 286 (244)
Sequences: 538 (388)
Seq/√Len: 24.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
105_T157_L4.7291.00
228_L260_V4.6211.00
82_I106_I4.1731.00
66_S69_S3.7381.00
167_W179_K3.4001.00
40_S43_N3.3251.00
262_M268_I3.0631.00
232_T236_E3.0261.00
119_E171_E2.7080.99
228_L268_I2.5190.99
46_A50_G2.4620.99
260_V279_R2.4550.99
104_E155_E2.4320.98
73_F84_E2.3500.98
62_S106_I2.3420.98
222_S272_S2.2810.98
126_V161_R2.2670.98
38_A42_Q2.2130.97
84_E93_R2.1680.97
104_E171_E2.1470.97
107_E158_A2.1260.96
48_I51_K2.1040.96
65_W70_N2.0820.96
112_N266_G2.0750.96
115_V219_L2.0030.95
70_N87_T1.9880.95
37_H43_N1.9470.94
177_V240_E1.9100.93
151_N219_L1.8790.93
190_H194_D1.8570.92
209_A240_E1.8220.92
207_S223_H1.7990.91
205_D223_H1.7960.91
104_E119_E1.7710.90
61_S104_E1.7410.90
119_E155_E1.6680.88
151_N171_E1.6440.87
115_V157_L1.6420.87
117_S157_L1.6120.86
263_D267_N1.5940.85
158_A169_F1.5930.85
113_Q128_S1.5920.85
81_A94_T1.5880.85
66_S108_Y1.5500.83
222_S258_E1.5420.83
85_M127_I1.5170.82
155_E256_Q1.4870.81
135_V140_K1.4800.80
56_I74_S1.4620.79
219_L262_M1.4590.79
258_E273_E1.4540.79
56_I73_F1.4260.78
157_L256_Q1.4020.76
177_V186_S1.3880.76
51_K90_D1.3820.75
118_D154_F1.3750.75
165_T179_K1.3700.75
113_Q126_V1.3520.74
104_E258_E1.3390.73
66_S177_V1.3150.72
156_G209_A1.3030.71
117_S270_I1.3000.71
102_D119_E1.2890.70
104_E273_E1.2880.70
37_H42_Q1.2860.70
50_G215_K1.2780.69
155_E171_E1.2650.69
243_L280_F1.2610.68
171_E174_P1.2570.68
61_S155_E1.2480.68
273_E277_F1.2480.68
79_P87_T1.2190.66
104_E151_N1.2180.66
118_D222_S1.2110.65
171_E207_S1.1990.64
53_I56_I1.1960.64
62_S259_G1.1950.64
252_H280_F1.1950.64
39_A98_D1.1920.64
157_L209_A1.1860.64
260_V268_I1.1800.63
56_I60_I1.1770.63
66_S73_F1.1770.63
39_A123_A1.1730.63
37_H40_S1.1710.62
171_E258_E1.1640.62
205_D256_Q1.1610.62
41_F45_H1.1590.62
154_F258_E1.1570.62
154_F222_S1.1560.61
112_N161_R1.1550.61
171_E205_D1.1520.61
74_S162_Q1.1490.61
168_F220_V1.1480.61
155_E207_S1.1400.60
119_E259_G1.1390.60
118_D228_L1.1120.58
119_E268_I1.1050.58
116_I270_I1.1030.58
63_L261_A1.0830.56
124_I229_Q1.0780.56
52_E66_S1.0760.56
160_S212_N1.0730.56
107_E157_L1.0720.56
107_E169_F1.0620.55
85_M269_Y1.0610.55
73_F95_I1.0590.55
82_I115_V1.0580.55
73_F113_Q1.0570.55
155_E258_E1.0560.54
129_L133_S1.0500.54
228_L277_F1.0480.54
77_N117_S1.0470.54
47_T65_W1.0450.54
193_K248_R1.0430.54
171_E273_E1.0370.53
64_T156_G1.0370.53
210_E262_M1.0360.53
37_H41_F1.0240.52
166_F277_F1.0230.52
130_T133_S1.0180.52
116_I193_K1.0110.51
227_A257_A1.0050.51
109_I222_S1.0030.51
258_E274_P0.9930.50
232_T255_K0.9910.50
255_K277_F0.9900.50
243_L249_G0.9850.49
138_L192_S0.9790.49
239_G266_G0.9700.48
165_T220_V0.9680.48
102_D155_E0.9680.48
43_N251_S0.9660.48
189_L234_V0.9610.48
255_K272_S0.9530.47
179_K272_S0.9420.46
95_I130_T0.9390.46
164_H194_D0.9290.45
197_L200_Q0.9290.45
121_D126_V0.9250.45
141_I144_P0.9230.45
155_E223_H0.9190.45
135_V238_I0.9190.45
148_S228_L0.9160.44
157_L183_L0.9120.44
124_I177_V0.9110.44
206_V222_S0.9100.44
38_A41_F0.9090.44
170_K222_S0.9080.44
243_L269_Y0.9070.44
105_T160_S0.8990.43
158_A261_A0.8960.43
119_E151_N0.8930.43
114_F127_I0.8840.42
137_I248_R0.8820.42
190_H262_M0.8790.42
61_S280_F0.8720.41
109_I113_Q0.8720.41
185_S192_S0.8710.41
39_A262_M0.8680.41
118_D170_K0.8590.40
73_F83_V0.8580.40
188_E234_V0.8560.40
59_N105_T0.8470.39
76_I118_D0.8470.39
105_T169_F0.8430.39
250_L256_Q0.8410.39
40_S47_T0.8330.39
167_W210_E0.8300.38
63_L99_F0.8290.38
207_S258_E0.8260.38
188_E228_L0.8250.38
62_S209_A0.8250.38
60_I74_S0.8220.38
167_W208_G0.8200.38
59_N218_L0.8160.37
164_H184_L0.8110.37
119_E172_K0.8110.37
73_F219_L0.8100.37
109_I235_G0.8060.37
224_E228_L0.8060.37
59_N77_N0.8050.37
188_E195_E0.8040.37
117_S229_Q0.8010.36
77_N102_D0.7980.36
247_S251_S0.7970.36
131_P137_I0.7960.36
127_I218_L0.7950.36
56_I79_P0.7940.36
108_Y159_Y0.7880.36
99_F112_N0.7860.35
104_E221_L0.7860.35
45_H48_I0.7850.35
74_S125_Y0.7840.35
218_L268_I0.7840.35
160_S163_D0.7840.35
60_I78_K0.7820.35
217_T232_T0.7820.35
155_E222_S0.7810.35
260_V270_I0.7790.35
142_K185_S0.7740.35
98_D136_K0.7730.35
62_S208_G0.7730.35
117_S184_L0.7700.34
204_D226_R0.7630.34
89_G174_P0.7590.34
170_K205_D0.7570.33
194_D198_Q0.7570.33
77_N258_E0.7540.33
116_I127_I0.7480.33
203_L220_V0.7460.33
206_V255_K0.7440.33
102_D205_D0.7410.32
144_P228_L0.7400.32
103_L149_P0.7360.32
168_F270_I0.7300.32
189_L192_S0.7300.32
197_L208_G0.7260.32
146_Q150_T0.7230.31
120_R145_L0.7210.31
169_F223_H0.7200.31
156_G210_E0.7190.31
216_N259_G0.7170.31
72_L269_Y0.7160.31
135_V199_R0.7140.31
102_D171_E0.7140.31
38_A47_T0.7140.31
210_E261_A0.7130.31
74_S85_M0.7110.31
97_L100_V0.7060.30
101_K275_N0.7030.30
106_I115_V0.7030.30
221_L275_N0.7010.30
154_F179_K0.6910.29
154_F178_Y0.6900.29
115_V182_G0.6900.29
164_H167_W0.6860.29
137_I142_K0.6830.29
66_S160_S0.6790.29
114_F158_A0.6780.29
104_E174_P0.6720.28
64_T105_T0.6720.28
64_T70_N0.6710.28
192_S195_E0.6630.28
243_L257_A0.6610.28
161_R236_E0.6600.28
53_I119_E0.6520.27
144_P248_R0.6500.27
104_E274_P0.6500.27
62_S114_F0.6470.27
139_K192_S0.6470.27
56_I85_M0.6470.27
61_S243_L0.6460.27
222_S235_G0.6440.27
118_D172_K0.6440.27
68_Q108_Y0.6430.27
156_G169_F0.6420.27
86_T90_D0.6410.26
108_Y118_D0.6410.26
229_Q238_I0.6400.26
82_I129_L0.6390.26
183_L269_Y0.6390.26
39_A46_A0.6380.26
69_S95_I0.6370.26
39_A112_N0.6360.26
61_S171_E0.6350.26
230_E239_G0.6330.26
221_L250_L0.6330.26
106_I156_G0.6320.26
37_H45_H0.6310.26
158_A220_V0.6300.26
157_L229_Q0.6300.26
214_Q263_D0.6300.26
157_L253_N0.6290.26
52_E211_F0.6290.26
64_T208_G0.6270.26
67_A208_G0.6260.26
68_Q112_N0.6260.26
71_T84_E0.6250.26
43_N47_T0.6210.25
160_S269_Y0.6190.25
162_Q215_K0.6170.25
166_F185_S0.6140.25
37_H47_T0.6130.25
151_N222_S0.6120.25
221_L228_L0.6100.25
164_H176_E0.6090.25
122_Y206_V0.6080.25
168_F180_V0.6050.24
85_M106_I0.6050.24
41_F46_A0.6050.24
109_I175_I0.6050.24
151_N271_V0.6040.24
77_N118_D0.6040.24
178_Y269_Y0.6040.24
190_H193_K0.6030.24
63_L143_I0.6010.24
41_F48_I0.6000.24
198_Q229_Q0.5990.24
155_E273_E0.5980.24
191_I248_R0.5940.24
172_K230_E0.5930.24
44_Y221_L0.5920.24
170_K206_V0.5910.24
118_D207_S0.5870.24
263_D271_V0.5860.23
60_I80_A0.5860.23
178_Y210_E0.5850.23
79_P134_E0.5840.23
116_I181_N0.5840.23
74_S78_K0.5830.23
161_R195_E0.5800.23
59_N104_E0.5800.23
115_V208_G0.5800.23
148_S166_F0.5790.23
125_Y168_F0.5780.23
221_L260_V0.5760.23
62_S205_D0.5740.23
208_G254_I0.5700.23
261_A267_N0.5700.23
39_A43_N0.5700.23
60_I170_K0.5670.23
44_Y47_T0.5630.22
145_L236_E0.5620.22
115_V125_Y0.5610.22
165_T215_K0.5580.22
206_V272_S0.5560.22
117_S176_E0.5560.22
63_L74_S0.5540.22
156_G274_P0.5520.22
45_H52_E0.5520.22
53_I154_F0.5520.22
119_E156_G0.5470.22
56_I95_I0.5460.21
169_F244_T0.5450.21
89_G222_S0.5430.21
52_E218_L0.5410.21
105_T156_G0.5340.21
42_Q239_G0.5310.21
42_Q96_P0.5300.21
73_F251_S0.5290.21
158_A211_F0.5250.20
109_I160_S0.5230.20
204_D261_A0.5220.20
89_G151_N0.5220.20
119_E273_E0.5200.20
189_L193_K0.5190.20
138_L146_Q0.5180.20
102_D258_E0.5170.20
158_A218_L0.5150.20
123_A183_L0.5120.20
109_I115_V0.5120.20
254_I257_A0.5120.20
263_D266_G0.5090.20
251_S260_V0.5090.20
95_I197_L0.5090.20
179_K268_I0.5080.20
61_S122_Y0.5070.20
240_E253_N0.5070.20
129_L148_S0.5070.20
103_L114_F0.5050.20
179_K270_I0.5050.20
44_Y50_G0.5040.19
127_I209_A0.5040.19
69_S84_E0.5030.19
61_S258_E0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3qqzA 1 0.8497 100 0.405 Contact Map
4a0pA 1 0.8147 99.9 0.522 Contact Map
1ijqA 1 0.8042 99.9 0.535 Contact Map
3v65B 1 0.8566 99.9 0.539 Contact Map
3s94A 1 0.7517 99.9 0.54 Contact Map
3sovA 1 0.8147 99.9 0.541 Contact Map
3v64C 1 0.8636 99.9 0.541 Contact Map
3fvzA 1 0.8671 99.9 0.542 Contact Map
3m0cC 1 0.8811 99.9 0.551 Contact Map
3p5bL 1 0.8846 99.9 0.552 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0087 seconds.