GREMLIN Database
YJIH - Uncharacterized protein YjiH
UniProt: P39379 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12569
Length: 227 (207)
Sequences: 130 (81)
Seq/√Len: 5.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
57_Q161_I2.7540.69
42_W46_F2.7240.68
19_I23_L2.6070.64
165_Y170_S2.5810.63
18_G21_G2.5750.63
100_T105_G2.3910.57
28_T113_M2.3700.56
134_N162_F2.3660.56
176_Y194_P2.3160.54
123_I162_F2.3130.54
97_I174_T2.2010.51
32_F109_A2.1590.49
32_F137_N2.1180.48
167_T170_S2.0370.45
134_N165_Y1.9830.43
133_A171_A1.9680.43
127_C150_Q1.9490.42
146_K169_G1.9190.41
25_F91_I1.8880.40
120_L181_V1.8450.39
54_S57_Q1.8350.38
99_I118_K1.8310.38
75_G180_G1.8200.38
103_L141_A1.8150.38
128_S183_V1.7690.36
66_T189_T1.7630.36
72_G83_A1.6920.34
208_I211_V1.6380.32
169_G174_T1.6370.32
116_V128_S1.6310.32
150_Q199_L1.6100.31
50_V199_L1.6070.31
102_G183_V1.6010.31
27_L118_K1.6000.31
101_D192_I1.5890.31
29_I200_V1.5610.30
81_L95_G1.5530.30
164_A205_G1.5380.29
169_G177_F1.5230.29
156_E159_K1.5200.29
26_F157_R1.5120.28
107_R114_T1.4920.28
45_V179_S1.4740.27
110_Q186_F1.4530.27
199_L203_F1.4390.26
149_A161_I1.4310.26
32_F83_A1.4160.26
42_W184_F1.4070.26
93_S137_N1.4000.25
132_I168_S1.3790.25
172_I199_L1.3780.25
134_N207_N1.3780.25
28_T136_Q1.3660.24
183_V204_V1.3460.24
50_V141_A1.3460.24
75_G78_D1.3370.24
81_L114_T1.3350.24
106_L178_S1.3350.24
25_F131_L1.3210.23
14_T118_K1.3150.23
22_Y105_G1.3090.23
101_D162_F1.3050.23
161_I189_T1.2900.23
94_L195_L1.2890.23
69_R133_A1.2740.22
92_L96_I1.2740.22
48_F55_F1.2710.22
26_F46_F1.2680.22
162_F207_N1.2460.22
157_R195_L1.2460.22
36_F196_A1.2350.21
102_G113_M1.2290.21
77_K100_T1.2180.21
134_N170_S1.2160.21
69_R179_S1.2070.21
67_S198_I1.2070.21
38_G191_V1.2000.20
187_L219_R1.1940.20
30_I35_V1.1920.20
41_S155_T1.1890.20
56_G70_G1.1800.20
72_G152_G1.1780.20
16_K30_I1.1760.20
45_V171_A1.1710.20
176_Y184_F1.1560.20
162_F165_Y1.1560.20
138_T191_V1.1540.19
129_L142_A1.1530.19
25_F183_V1.1390.19
22_Y195_L1.1360.19
25_F181_V1.1330.19
91_I102_G1.1320.19
92_L219_R1.1290.19
195_L204_V1.1210.19
87_A213_L1.0990.18
58_L65_T1.0960.18
113_M143_G1.0900.18
45_V69_R1.0880.18
52_N77_K1.0810.18
37_S197_V1.0790.18
84_L203_F1.0600.18
69_R78_D1.0590.18
146_K177_F1.0500.17
136_Q168_S1.0500.17
133_A201_F1.0470.17
23_L150_Q1.0460.17
106_L141_A1.0440.17
120_L219_R1.0360.17
64_A123_I1.0290.17
182_A186_F1.0240.17
136_Q176_Y1.0180.17
67_S150_Q1.0150.17
174_T195_L1.0130.17
113_M176_Y1.0100.17
81_L189_T1.0090.17
131_L165_Y1.0060.16
24_A71_A1.0060.16
132_I213_L1.0040.16
29_I147_E1.0000.16
94_L168_S0.9990.16
23_L64_A0.9970.16
46_F52_N0.9940.16
32_F93_S0.9920.16
174_T197_V0.9860.16
29_I92_L0.9840.16
28_T135_L0.9820.16
105_G110_Q0.9770.16
83_A158_D0.9710.16
140_A182_A0.9700.16
54_S69_R0.9700.16
199_L214_N0.9670.16
25_F134_N0.9630.16
203_F214_N0.9630.16
86_L175_N0.9610.16
146_K190_S0.9600.16
50_V103_L0.9550.16
78_D207_N0.9470.15
135_L177_F0.9430.15
21_G132_I0.9390.15
103_L131_L0.9350.15
172_I189_T0.9310.15
19_I60_G0.9290.15
76_A80_F0.9100.15
35_V180_G0.9060.15
134_N183_V0.9050.15
177_F184_F0.9020.15
24_A151_E0.9010.15
157_R217_E0.8930.14
81_L154_I0.8930.14
105_G143_G0.8870.14
39_T105_G0.8850.14
38_G154_I0.8830.14
21_G121_L0.8820.14
54_S77_K0.8820.14
60_G152_G0.8750.14
64_A146_K0.8700.14
103_L144_M0.8700.14
134_N167_T0.8690.14
118_K130_A0.8590.14
95_G214_N0.8500.14
153_E164_A0.8500.14
41_S105_G0.8500.14
33_S56_G0.8480.14
144_M212_W0.8450.14
83_A137_N0.8450.14
39_T144_M0.8380.14
190_S194_P0.8380.14
131_L195_L0.8350.13
36_F197_V0.8280.13
16_K173_I0.8280.13
80_F104_G0.8270.13
159_K207_N0.8250.13
165_Y186_F0.8220.13
12_L173_I0.8200.13
74_A78_D0.8190.13
104_G130_A0.8190.13
77_K203_F0.8120.13
33_S70_G0.8030.13
129_L180_G0.8020.13
131_L135_L0.8010.13
58_L164_A0.7970.13
169_G198_I0.7940.13
142_A180_G0.7940.13
87_A95_G0.7920.13
121_L187_L0.7810.13
76_A82_F0.7790.13
145_T162_F0.7700.12
104_G145_T0.7670.12
184_F187_L0.7590.12
107_R123_I0.7570.12
128_S167_T0.7550.12
68_F84_L0.7540.12
22_Y33_S0.7540.12
140_A143_G0.7530.12
157_R178_S0.7500.12
173_I214_N0.7450.12
118_K185_A0.7450.12
25_F102_G0.7450.12
98_S195_L0.7440.12
72_G169_G0.7370.12
25_F167_T0.7340.12
166_Q175_N0.7330.12
30_I97_I0.7300.12
44_R219_R0.7290.12
128_S133_A0.7290.12
109_A114_T0.7230.12
182_A194_P0.7210.12
67_S85_E0.7200.12
132_I136_Q0.7180.12
30_I41_S0.7130.12
89_S110_Q0.7130.12
19_I196_A0.7110.12
51_L104_G0.7110.12
146_K194_P0.7090.12
107_R208_I0.7090.12
65_T123_I0.7040.12
165_Y176_Y0.6990.11
152_G211_V0.6980.11
101_D171_A0.6930.11
44_R50_V0.6920.11
165_Y207_N0.6920.11
17_V149_A0.6910.11
25_F160_V0.6840.11
146_K215_F0.6840.11
111_Q127_C0.6830.11
128_S213_L0.6820.11
36_F105_G0.6800.11
211_V219_R0.6700.11
157_R214_N0.6600.11
95_G205_G0.6590.11
116_V216_E0.6530.11
90_V109_A0.6520.11
78_D96_I0.6520.11
168_S184_F0.6470.11
122_G210_R0.6410.11
112_L152_G0.6390.11
19_I153_E0.6330.11
73_G79_G0.6310.11
78_D174_T0.6310.11
106_L110_Q0.6280.11
117_L121_L0.6280.11
77_K81_L0.6270.10
52_N69_R0.6250.10
90_V174_T0.6250.10
106_L174_T0.6240.10
78_D92_L0.6240.10
49_S94_L0.6220.10
75_G197_V0.6220.10
87_A211_V0.6200.10
114_T135_L0.6170.10
26_F195_L0.6150.10
149_A154_I0.6140.10
43_W167_T0.6130.10
27_L106_L0.6090.10
93_S109_A0.6060.10
17_V111_Q0.6040.10
35_V123_I0.6040.10
49_S185_A0.6020.10
121_L189_T0.6010.10
49_S107_R0.6010.10
105_G144_M0.5930.10
99_I158_D0.5860.10
117_L142_A0.5850.10
30_I147_E0.5850.10
58_L118_K0.5840.10
11_E208_I0.5820.10
91_I141_A0.5800.10
31_F94_L0.5800.10
92_L192_I0.5760.10
132_I155_T0.5760.10
87_A191_V0.5740.10
150_Q200_V0.5720.10
50_V198_I0.5720.10
184_F194_P0.5700.10
56_G130_A0.5660.10
123_I161_I0.5620.10
100_T133_A0.5590.10
32_F106_L0.5590.10
83_A111_Q0.5580.10
126_I197_V0.5560.10
11_E204_V0.5550.10
46_F112_L0.5550.10
37_S81_L0.5520.10
158_D208_I0.5440.09
167_T209_L0.5440.09
86_L166_Q0.5430.09
25_F50_V0.5380.09
141_A170_S0.5370.09
94_L146_K0.5300.09
168_S176_Y0.5300.09
24_A46_F0.5270.09
147_E196_A0.5260.09
52_N143_G0.5260.09
25_F113_M0.5250.09
70_G130_A0.5240.09
38_G197_V0.5170.09
87_A151_E0.5170.09
80_F171_A0.5160.09
133_A167_T0.5150.09
89_S206_A0.5110.09
16_K211_V0.5110.09
90_V138_T0.5100.09
105_G141_A0.5100.09
27_L42_W0.5090.09
31_F96_I0.5060.09
168_S201_F0.5050.09
17_V25_F0.5040.09
44_R141_A0.5030.09
99_I130_A0.5010.09
21_G105_G0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4pd6A 3 0.8811 98.3 0.907 Contact Map
2kncB 1 0.2379 10.9 0.974 Contact Map
4pl0A 2 0.8194 4.6 0.978 Contact Map
4r1iA 2 0.8899 4 0.979 Contact Map
3ne5A 3 0.7665 3.7 0.979 Contact Map
2lcnA 1 0.0837 3.4 0.979 Contact Map
2cfqA 1 0.8943 3.4 0.979 Contact Map
2jlnA 1 0.3568 2.8 0.98 Contact Map
1spfA 1 0.1233 2.8 0.98 Contact Map
3w4tA 1 0.3524 2.6 0.981 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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