GREMLIN Database
YJHR - Putative uncharacterized protein YjhR
UniProt: P39369 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12560
Length: 338 (288)
Sequences: 433 (402)
Seq/√Len: 23.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
63_I83_V5.5061.00
82_T92_A4.5901.00
103_Y111_F3.8541.00
99_F122_A3.6311.00
31_L52_V3.2641.00
87_H118_I3.0491.00
55_P120_N3.0111.00
95_A128_D2.9361.00
49_V95_A2.7420.99
5_H136_M2.5980.99
51_G97_V2.5970.99
189_H193_L2.3700.98
24_A66_S2.3210.98
233_I239_T2.3040.97
24_A62_A2.2340.97
110_R113_D2.1990.97
53_V101_P2.1850.96
231_R256_K2.1760.96
17_S93_E2.1430.96
25_E66_S2.1270.96
51_G94_R2.1240.96
56_F103_Y2.0880.95
135_D148_R2.0850.95
52_V96_I2.0820.95
54_T60_V2.0520.95
154_Y158_S1.9530.93
123_V136_M1.9450.93
5_H85_T1.9380.93
299_W304_R1.9210.93
103_Y113_D1.9150.93
118_I121_V1.8890.92
27_I83_V1.8510.91
30_W98_L1.8190.90
105_K138_L1.7860.90
96_I156_F1.7730.89
53_V89_L1.7580.89
56_F118_I1.7500.89
261_N265_E1.7450.89
87_H121_V1.7440.88
221_F233_I1.7270.88
149_G153_K1.7250.88
51_G55_P1.7010.87
101_P139_I1.6870.87
167_F170_R1.6680.86
265_E269_K1.6400.85
103_Y118_I1.6360.85
82_T94_R1.6180.84
51_G120_N1.6120.84
95_A127_K1.6040.84
204_I208_S1.5880.83
17_S112_L1.5810.83
120_N133_F1.5660.82
56_F87_H1.5590.82
27_I67_L1.5480.82
134_G139_I1.5320.81
298_N302_A1.5160.80
93_E127_K1.5140.80
281_H298_N1.5100.80
267_L271_G1.5000.79
95_A147_P1.4870.79
4_L104_S1.4810.79
94_R101_P1.4750.78
268_N272_I1.4700.78
163_L170_R1.4680.78
60_V63_I1.4620.78
94_R120_N1.4420.77
87_H103_Y1.4260.76
102_V139_I1.4190.75
93_E104_S1.4080.75
51_G139_I1.4050.75
240_D243_C1.3970.74
135_D139_I1.3870.74
19_H65_M1.3860.74
151_L155_L1.3640.72
27_I133_F1.3520.72
62_A66_S1.3500.72
59_Q100_S1.3480.72
17_S20_N1.3470.72
42_Y94_R1.3290.70
55_P151_L1.3190.70
84_G119_L1.3070.69
6_I10_G1.3050.69
267_L274_T1.2860.68
99_F113_D1.2850.68
96_I131_L1.2820.68
184_H193_L1.2750.67
100_S111_F1.2740.67
76_D153_K1.2700.67
92_A117_T1.2690.67
46_L49_V1.2650.67
134_G148_R1.2650.67
55_P94_R1.2640.67
38_I101_P1.2520.66
151_L154_Y1.2460.65
52_V200_A1.2430.65
30_W133_F1.2370.65
4_L30_W1.2340.65
129_S154_Y1.2260.64
101_P155_L1.2220.64
59_Q111_F1.2200.64
23_E100_S1.2190.64
257_Q275_K1.2120.63
42_Y124_S1.1930.62
91_G125_R1.1910.62
20_N23_E1.1900.62
203_K207_I1.1870.62
25_E62_A1.1860.61
189_H204_I1.1760.61
50_V54_T1.1750.61
299_W302_A1.1580.60
6_I92_A1.1540.59
53_V154_Y1.1530.59
147_P151_L1.1520.59
11_M21_P1.1520.59
6_I101_P1.1500.59
205_T210_W1.1460.59
264_V275_K1.1340.58
24_A100_S1.1340.58
103_Y110_R1.1320.58
251_D258_H1.1280.57
151_L158_S1.1260.57
38_I42_Y1.1220.57
282_S295_G1.1210.57
222_L268_N1.1150.57
164_Q167_F1.1150.57
55_P88_S1.1100.56
13_P64_K1.0980.55
6_I53_V1.0840.54
57_S122_A1.0740.54
212_S217_E1.0740.54
258_H262_D1.0600.53
3_Y10_G1.0600.53
6_I51_G1.0570.53
189_H199_G1.0490.52
290_E303_T1.0430.52
15_G109_G1.0360.51
155_L158_S1.0360.51
157_S275_K1.0350.51
18_R135_D1.0320.51
53_V94_R1.0280.51
139_I154_Y1.0240.50
15_G27_I1.0230.50
188_Q192_F1.0200.50
67_L83_V1.0080.49
84_G104_S1.0010.49
35_K81_L1.0010.49
297_F302_A1.0000.49
26_T133_F0.9980.48
87_H90_Q0.9950.48
81_L305_E0.9890.48
4_L29_A0.9830.47
10_G105_K0.9820.47
61_N64_K0.9740.47
100_S103_Y0.9700.46
115_N122_A0.9690.46
247_H253_R0.9680.46
102_V113_D0.9660.46
94_R97_V0.9650.46
34_H67_L0.9640.46
93_E148_R0.9640.46
300_F304_R0.9600.46
56_F113_D0.9590.46
21_P62_A0.9580.46
90_Q121_V0.9490.45
57_S110_R0.9470.45
104_S158_S0.9410.44
102_V111_F0.9400.44
98_L121_V0.9390.44
100_S117_T0.9370.44
289_E300_F0.9320.44
207_I217_E0.9290.44
133_F136_M0.9270.43
64_K100_S0.9200.43
84_G92_A0.9140.43
203_K227_L0.9120.42
105_K108_D0.9110.42
188_Q211_L0.9080.42
206_I247_H0.9050.42
33_A81_L0.9020.42
148_R152_A0.8940.41
56_F59_Q0.8930.41
30_W139_I0.8890.41
242_N246_A0.8870.41
116_S142_Q0.8800.40
302_A305_E0.8790.40
31_L120_N0.8780.40
37_D171_Q0.8740.40
256_K264_V0.8580.39
124_S129_S0.8560.39
123_V151_L0.8470.38
198_A216_V0.8470.38
292_L299_W0.8420.38
30_W131_L0.8370.37
226_A251_D0.8350.37
6_I9_R0.8340.37
129_S151_L0.8330.37
88_S94_R0.8320.37
104_S138_L0.8310.37
279_R283_K0.8280.37
281_H299_W0.8270.37
88_S92_A0.8260.37
101_P148_R0.8260.37
187_E200_A0.8250.37
56_F126_A0.8250.37
67_L123_V0.8160.36
189_H239_T0.8160.36
31_L94_R0.8150.36
90_Q125_R0.8140.36
240_D244_N0.8080.35
129_S155_L0.8030.35
199_G204_I0.8000.35
51_G89_L0.7990.35
8_G11_M0.7990.35
49_V158_S0.7960.35
288_D295_G0.7940.35
180_I208_S0.7930.34
32_V138_L0.7920.34
221_F239_T0.7900.34
123_V130_F0.7900.34
104_S155_L0.7900.34
23_E59_Q0.7840.34
267_L289_E0.7830.34
86_V126_A0.7830.34
296_S299_W0.7820.34
28_A83_V0.7820.34
93_E112_L0.7730.33
187_E193_L0.7730.33
195_K227_L0.7670.33
33_A94_R0.7670.33
221_F229_R0.7670.33
6_I33_A0.7660.33
74_G83_V0.7660.33
5_H119_L0.7650.33
293_C296_S0.7620.33
32_V70_L0.7620.33
208_S212_S0.7610.32
88_S124_S0.7610.32
96_I135_D0.7610.32
93_E135_D0.7610.32
95_A118_I0.7610.32
254_Q272_I0.7590.32
60_V128_D0.7580.32
115_N119_L0.7570.32
24_A86_V0.7540.32
51_G92_A0.7510.32
207_I210_W0.7480.32
23_E134_G0.7480.32
297_F301_S0.7480.32
104_S119_L0.7470.32
58_A129_S0.7470.32
104_S133_F0.7470.32
24_A28_A0.7470.32
202_K217_E0.7420.31
232_G241_K0.7400.31
124_S133_F0.7390.31
270_M274_T0.7390.31
180_I187_E0.7370.31
53_V92_A0.7360.31
117_T130_F0.7360.31
26_T135_D0.7350.31
54_T58_A0.7340.31
30_W130_F0.7340.31
56_F112_L0.7270.30
20_N125_R0.7270.30
20_N91_G0.7270.30
60_V94_R0.7260.30
92_A113_D0.7210.30
117_T136_M0.7190.30
18_R104_S0.7170.30
3_Y139_I0.7150.30
122_A133_F0.7140.30
87_H92_A0.7110.29
89_L98_L0.7100.29
195_K234_D0.7090.29
19_H64_K0.7080.29
202_K209_P0.7080.29
94_R124_S0.7070.29
199_G202_K0.7060.29
186_V194_N0.7050.29
184_H213_W0.7040.29
266_K274_T0.6970.29
292_L295_G0.6960.29
285_V291_L0.6930.28
119_L127_K0.6930.28
99_F132_V0.6930.28
67_L92_A0.6920.28
193_L221_F0.6920.28
285_V300_F0.6860.28
259_L269_K0.6850.28
54_T114_S0.6840.28
298_N301_S0.6830.28
288_D292_L0.6820.28
27_I104_S0.6780.28
286_I290_E0.6780.28
79_G265_E0.6780.28
68_R157_S0.6760.27
42_Y58_A0.6660.27
57_S61_N0.6660.27
103_Y117_T0.6650.27
42_Y121_V0.6640.27
209_P214_Q0.6600.27
86_V99_F0.6590.26
258_H261_N0.6590.26
187_E199_G0.6590.26
59_Q102_V0.6580.26
82_T151_L0.6520.26
301_S304_R0.6510.26
50_V70_L0.6490.26
160_N164_Q0.6480.26
117_T124_S0.6480.26
29_A141_M0.6480.26
235_I245_I0.6450.26
89_L152_A0.6450.26
60_V64_K0.6430.26
292_L305_E0.6410.26
237_V244_N0.6410.26
290_E293_C0.6400.25
51_G84_G0.6380.25
225_M231_R0.6360.25
118_I130_F0.6360.25
181_S241_K0.6360.25
262_D265_E0.6360.25
87_H95_A0.6340.25
31_L88_S0.6320.25
130_F151_L0.6310.25
257_Q270_M0.6290.25
284_I305_E0.6290.25
279_R287_E0.6240.25
5_H158_S0.6230.25
24_A133_F0.6230.25
114_S124_S0.6220.25
266_K277_V0.6200.24
76_D83_V0.6190.24
137_D140_E0.6190.24
203_K218_Q0.6190.24
294_V297_F0.6170.24
199_G221_F0.6170.24
116_S131_L0.6160.24
7_D149_G0.6140.24
225_M233_I0.6140.24
206_I238_V0.6140.24
276_L279_R0.6130.24
87_H129_S0.6130.24
87_H110_R0.6120.24
111_F115_N0.6120.24
89_L118_I0.6120.24
42_Y88_S0.6070.24
3_Y134_G0.6070.24
188_Q209_P0.6040.24
292_L300_F0.6020.23
186_V199_G0.6000.23
87_H117_T0.6000.23
3_Y110_R0.5980.23
191_E253_R0.5970.23
278_N285_V0.5950.23
17_S120_N0.5950.23
104_S135_D0.5950.23
295_G305_E0.5930.23
157_S254_Q0.5910.23
265_E289_E0.5900.23
38_I57_S0.5870.23
279_R282_S0.5860.23
30_W84_G0.5850.23
259_L264_V0.5840.23
15_G62_A0.5820.22
90_Q126_A0.5820.22
109_G112_L0.5790.22
38_I124_S0.5780.22
120_N124_S0.5760.22
177_H180_I0.5740.22
213_W256_K0.5730.22
129_S133_F0.5730.22
225_M240_D0.5720.22
278_N303_T0.5680.22
92_A124_S0.5680.22
280_V287_E0.5680.22
205_T211_L0.5670.22
24_A130_F0.5660.22
121_V126_A0.5650.22
84_G115_N0.5600.21
110_R118_I0.5590.21
293_C298_N0.5580.21
51_G117_T0.5560.21
184_H195_K0.5540.21
101_P118_I0.5520.21
58_A101_P0.5520.21
63_I147_P0.5510.21
34_H95_A0.5490.21
191_E198_A0.5490.21
127_K283_K0.5490.21
259_L262_D0.5480.21
189_H201_Q0.5480.21
51_G131_L0.5470.21
66_S119_L0.5470.21
84_G87_H0.5460.21
64_K68_R0.5440.21
12_K146_S0.5440.21
23_E125_R0.5440.21
23_E91_G0.5440.21
31_L131_L0.5430.21
55_P82_T0.5410.21
75_K95_A0.5390.20
227_L267_L0.5390.20
11_M62_A0.5330.20
93_E118_I0.5330.20
111_F118_I0.5310.20
112_L148_R0.5310.20
146_S150_L0.5280.20
19_H102_V0.5280.20
300_F303_T0.5240.20
5_H104_S0.5220.20
265_E273_A0.5220.20
191_E194_N0.5220.20
63_I68_R0.5170.19
296_S302_A0.5170.19
129_S142_Q0.5150.19
56_F121_V0.5150.19
104_S109_G0.5140.19
38_I129_S0.5140.19
83_V104_S0.5140.19
50_V102_V0.5120.19
187_E233_I0.5120.19
60_V104_S0.5120.19
52_V81_L0.5080.19
264_V271_G0.5080.19
253_R259_L0.5080.19
89_L121_V0.5070.19
28_A101_P0.5050.19
135_D154_Y0.5040.19
87_H136_M0.5030.19
187_E232_G0.5020.19
270_M273_A0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4b3fX 1 0.4497 100 0.483 Contact Map
2xzlA 1 0.497 100 0.509 Contact Map
2wjyA 1 0.4941 100 0.523 Contact Map
2gk6A 1 0.4704 100 0.532 Contact Map
4pj3A 1 0.5888 100 0.592 Contact Map
3vkwA 1 0.4053 99.8 0.733 Contact Map
4n0nA 1 0.2811 99.7 0.759 Contact Map
3dmnA 1 0.4142 99.7 0.762 Contact Map
3e1sA 1 0.4497 99.4 0.807 Contact Map
1w36D 1 0.3432 99.3 0.818 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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